Year |
Citation |
Score |
2024 |
An J, Kim K, Lim HJ, Kim HY, Shin J, Park I, Cho I, Kim HY, Kim S, McLean C, Choi KY, Kim Y, Lee KH, Kim JS. Early onset diagnosis in Alzheimer's disease patients via amyloid-β oligomers-sensing probe in cerebrospinal fluid. Nature Communications. 15: 1004. PMID 38307843 DOI: 10.1038/s41467-024-44818-x |
0.564 |
|
2023 |
Cha M, Dagar A, Lee S, Cho I, Lee D, Kim K, Park I, Yoon S, Kim HY, Kim I, Kim Y. Benzo[]imidazole-pyrrolo[1,2-]pyrazine Hybrids Ameliorate Amyloid Aggregates in the Brain of Alzheimer Transgenic Mice. Acs Chemical Neuroscience. PMID 37552840 DOI: 10.1021/acschemneuro.2c00547 |
0.598 |
|
2023 |
Lee D, Ryoo JE, Hong S, Kim HY, Kim Y. Carprofen alleviates Alzheimer-like phenotypes of 5XFAD transgenic mice by targeting the pathological hallmarks induced by amyloid-β aggregation. Scientific Reports. 13: 10889. PMID 37407605 DOI: 10.1038/s41598-023-36167-4 |
0.612 |
|
2023 |
Lee S, Dagar A, Cho I, Kim K, Park IW, Yoon S, Cha M, Shin J, Kim HY, Kim I, Kim Y. 4-Acyl-3,4-dihydropyrrolo[1,2-]pyrazine Derivative Rescued the Hippocampal-Dependent Cognitive Decline of 5XFAD Transgenic Mice by Dissociating Soluble and Insoluble Aβ Aggregates. Acs Chemical Neuroscience. PMID 37171100 DOI: 10.1021/acschemneuro.2c00788 |
0.607 |
|
2023 |
Kim HJ, Kim H, Park D, Yoon DS, San Lee J, Hwang KS. Plasma-based diagnostic and screening platform using a combination of biosensing signals in Alzheimer's disease. Biosensors & Bioelectronics. 230: 115246. PMID 37003061 DOI: 10.1016/j.bios.2023.115246 |
0.371 |
|
2023 |
Cui J, Ye S, Shin D, Cho I, Kim HY, Kwon Y, Park K, Nam SJ, Kim Y, Oh DC. Glycosylated and Succinylated Macrocyclic Lactones with Amyloid-β-Aggregation-Regulating Activity from a Marine sp. Marine Drugs. 21. PMID 36827108 DOI: 10.3390/md21020067 |
0.5 |
|
2023 |
Cho I, Lee H, Lee D, Park IW, Yoon S, Kim HY, Kim Y. Solid-phase synthesis and pathological evaluation of pyroglutamate amyloid-β peptide. Scientific Reports. 13: 505. PMID 36627316 DOI: 10.1038/s41598-022-26616-x |
0.539 |
|
2022 |
Cho I, Yoon S, Park S, Hong SW, Cho E, Kim E, Kim HY, Kim Y. Immobilized Amyloid Hexamer Fragments to Map Active Sites of Amyloid-Targeting Chemicals. Acs Chemical Neuroscience. PMID 36445044 DOI: 10.1021/acschemneuro.2c00449 |
0.541 |
|
2022 |
Lee HY, Yoon S, Lee JH, Park K, Jung Y, Cho I, Lee D, Shin J, Kim K, Kim S, Kim J, Kim K, Han SH, Kim SM, Kim HJ, ... Kim HY, et al. Aryloxypropanolamine targets amyloid aggregates and reverses Alzheimer-like phenotypes in Alzheimer mouse models. Alzheimer's Research & Therapy. 14: 177. PMID 36443837 DOI: 10.1186/s13195-022-01112-6 |
0.49 |
|
2022 |
Lee H, Baek S, Cha M, Yang SH, Cho I, Shin H, Lee S, Kim HY, Lee S, Shin J, Lee D, Kim K, Park I, Yoon S, Kim J, ... ... Kim HJ, et al. Amyloid Against Amyloid: Dimeric Amyloid Fragment Ameliorates Cognitive Impairments by Direct Clearance of Oligomers and Plaques. Angewandte Chemie (International Ed. in English). PMID 36316282 DOI: 10.1002/anie.202210209 |
0.579 |
|
2022 |
Lee D, Kim HV, Kim HY, Kim Y. Chemical-Driven Outflow of Dissociated Amyloid Burden from Brain to Blood. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2104542. PMID 35106958 DOI: 10.1002/advs.202104542 |
0.583 |
|
2021 |
Kim K, Lee JH, Kim S, Lee S, Lee D, Kim HY, Kim I, Kim Y. Anti-amyloidogenic indolizino[3,2-]quinolines as imaging probes differentiating dense-core, diffuse, and coronal plaques of amyloid-β. Rsc Medicinal Chemistry. 12: 1926-1934. PMID 34825188 DOI: 10.1039/d1md00030f |
0.565 |
|
2021 |
Kim HJ, Park D, Yun G, Kim H, Kim HG, Lee KM, Hong IK, Park KC, Lee JS, Hwang KS. Screening for cerebral amyloid angiopathy based on serological biomarkers analysis using a dielectrophoretic force-driven biosensor platform. Lab On a Chip. PMID 34724019 DOI: 10.1039/d1lc00742d |
0.405 |
|
2021 |
Park S, Kim HY, Oh HA, Shin J, Park IW, Yoon S, Woo DH, Kim Y. Quinacrine directly dissociates amyloid plaques in the brain of 5XFAD transgenic mouse model of Alzheimer's disease. Scientific Reports. 11: 12043. PMID 34103615 DOI: 10.1038/s41598-021-91563-y |
0.594 |
|
2021 |
Kim D, Lee JH, Kim HY, Shin J, Kim K, Lee S, Park J, Kim I, Kim Y. Correction: Fluorescent indolizine derivative YI-13 detects amyloid-β monomers, dimers, and plaques in the brain of 5XFAD Alzheimer transgenic mouse model. Plos One. 16: e0250194. PMID 33831134 DOI: 10.1371/journal.pone.0250194 |
0.488 |
|
2020 |
Kim D, Lee JH, Kim HY, Shin J, Kim K, Lee S, Park J, Kim J, Kim Y. Fluorescent indolizine derivative YI-13 detects amyloid-β monomers, dimers, and plaques in the brain of 5XFAD Alzheimer transgenic mouse model. Plos One. 15: e0243041. PMID 33362250 DOI: 10.1371/journal.pone.0243041 |
0.583 |
|
2020 |
Kim D, Bae GH, Kim HY, Jeon H, Kim K, Shin J, Lee S, Hong S, Kim I, Kim Y. Orally Administered Benzofuran Derivative Disaggregated Aβ Plaques and Oligomers in the Brain of 5XFAD Alzheimer Transgenic Mouse. Acs Chemical Neuroscience. PMID 33332107 DOI: 10.1021/acschemneuro.0c00606 |
0.613 |
|
2020 |
Kim HY, Lee H, Lee JK, Kim HV, Kim KS, Kim Y. Bicine promotes rapid formation of β-sheet-rich amyloid-β fibrils. Plos One. 15: e0240608. PMID 33048999 DOI: 10.1371/journal.pone.0240608 |
0.553 |
|
2020 |
Lee JC, Kim HY, Lee S, Shin J, Kim HV, Kim K, Baek S, Lee D, Jeon H, Kim D, Yang SH, Han G, Park K, Choi J, Park J, et al. Discovery of chemicals to clear or indicate amyloid aggregates by targeting memory-impairing anti-parallel Aβ dimers. Angewandte Chemie (International Ed. in English). PMID 32233096 DOI: 10.1002/Anie.202002574 |
0.596 |
|
2020 |
Heo JY, Nam MH, Yoon HH, Kim J, Hwang YJ, Won W, Woo DH, Lee JA, Park HJ, Jo S, Lee MJ, Kim S, Shim JE, Jang DP, Kim KI, ... ... Kim HY, et al. Aberrant Tonic Inhibition of Dopaminergic Neuronal Activity Causes Motor Symptoms in Animal Models of Parkinson's Disease. Current Biology : Cb. PMID 31928877 DOI: 10.1016/J.Cub.2019.11.079 |
0.312 |
|
2020 |
Kwak DE, Ko T, Koh HS, Ji YW, Shin J, Kim K, Kim HY, Lee HK, Kim Y. Alterations of aqueous humor Aβ levels in Aβ-infused and transgenic mouse models of Alzheimer disease. Plos One. 15: e0227618. PMID 31923257 DOI: 10.1371/Journal.Pone.0227618 |
0.582 |
|
2019 |
Lee H, Kim D, Lee W, Kim HY, Kim Y. Preventive approach for overcoming dementia. Archives of Pharmacal Research. PMID 31187441 DOI: 10.1007/S12272-019-01168-3 |
0.402 |
|
2019 |
Lee D, Kim SM, Kim HY, Kim Y. Fluorescence chemicals to detect insoluble and soluble amyloid-β aggregates. Acs Chemical Neuroscience. PMID 31009195 DOI: 10.1021/Acschemneuro.9B00199 |
0.574 |
|
2019 |
Kim Y, Yoo YK, Kim HY, Roh JH, Kim J, Baek S, Lee JC, Kim HJ, Chae MS, Jeong D, Park D, Lee S, Jang H, Kim K, Lee JH, et al. Comparative analyses of plasma amyloid-β levels in heterogeneous and monomerized states by interdigitated microelectrode sensor system. Science Advances. 5: eaav1388. PMID 31001580 DOI: 10.1126/Sciadv.Aav1388 |
0.56 |
|
2018 |
Shim HG, Jang SS, Kim SH, Hwang EM, Min JO, Kim HY, Kim YS, Ryu C, Chung G, Kim Y, Yoon BE, Kim SJ. TNF-α increases the intrinsic excitability of cerebellar Purkinje cells through elevating glutamate release in Bergmann Glia. Scientific Reports. 8: 11589. PMID 30072733 DOI: 10.1038/S41598-018-29786-9 |
0.329 |
|
2017 |
Jang H, Lee S, Choi SL, Kim HY, Baek S, Kim Y. Taurine Directly Binds to Oligomeric Amyloid-β and Recovers Cognitive Deficits in Alzheimer Model Mice. Advances in Experimental Medicine and Biology. 975: 233-241. PMID 28849459 DOI: 10.1007/978-94-024-1079-2_21 |
0.549 |
|
2017 |
Kim HY, Yang SH, Yoon J, Jang H, Baek S, Shin J, Kim SH, Kim Y. Taurine-Carbohydrate Derivative Stimulates Fibrillogenesis of Amyloid-β and Reduce Alzheimer-Like Behaviors. Advances in Experimental Medicine and Biology. 975: 225-232. PMID 28849458 DOI: 10.1007/978-94-024-1079-2_20 |
0.611 |
|
2017 |
Yoo YK, Kim J, Kim G, Kim YS, Kim HY, Lee S, Cho WW, Kim S, Lee SM, Lee BC, Lee JH, Hwang KS. A highly sensitive plasma-based amyloid-β detection system through medium-changing and noise cancellation system for early diagnosis of the Alzheimer's disease. Scientific Reports. 7: 8882. PMID 28827785 DOI: 10.1038/S41598-017-09370-3 |
0.336 |
|
2017 |
Kim HY, Lee D, Ryu KY, Choi I. A gold nanoparticle-mediated rapid in vitro assay of anti-aggregation reagents for amyloid β and its validation. Chemical Communications (Cambridge, England). PMID 28338146 DOI: 10.1039/c7cc00358g |
0.319 |
|
2016 |
Kim HY, Kim HV, Lee DK, Yang SH, Kim Y. Rapid and sustained cognitive recovery in APP/PS1 transgenic mice by co-administration of EPPS and donepezil. Scientific Reports. 6: 34165. PMID 27796293 DOI: 10.1038/Srep34165 |
0.554 |
|
2016 |
Kim HY, Lee DK, Chung BR, Kim HV, Kim Y. Intracerebroventricular Injection of Amyloid-β Peptides in Normal Mice to Acutely Induce Alzheimer-like Cognitive Deficits. Journal of Visualized Experiments : Jove. PMID 27023127 DOI: 10.3791/53308 |
0.591 |
|
2016 |
Kim HY, Kim HV, Jo S, Lee CJ, Choi SY, Kim DJ, Kim Y. Corrigendum: EPPS rescues hippocampus-dependent cognitive deficits in APP/PS1 mice by disaggregation of amyloid-β oligomers and plaques. Nature Communications. 7: 10755. PMID 26877163 DOI: 10.1038/Ncomms10755 |
0.428 |
|
2016 |
Cho SM, Lee S, Yang SH, Kim HY, Lee MJ, Kim HV, Kim J, Baek S, Yun J, Kim D, Kim YK, Cho Y, Woo J, Kim TS, Kim Y. Age-dependent inverse correlations in CSF and plasma amyloid-β(1-42) concentrations prior to amyloid plaque deposition in the brain of 3xTg-AD mice. Scientific Reports. 6: 20185. PMID 26830653 DOI: 10.1038/Srep20185 |
0.565 |
|
2015 |
Kim HY, Kim HV, Jo S, Lee CJ, Choi SY, Kim DJ, Kim Y. EPPS rescues hippocampus-dependent cognitive deficits in APP/PS1 mice by disaggregation of amyloid-β oligomers and plaques. Nature Communications. 6: 8997. PMID 26646366 DOI: 10.1038/Ncomms9997 |
0.612 |
|
2015 |
Yang Y, Kim J, Kim HY, Ryoo N, Lee S, Kim Y, Rhim H, Shin YK. Amyloid-β Oligomers May Impair SNARE-Mediated Exocytosis by Direct Binding to Syntaxin 1a. Cell Reports. PMID 26279571 DOI: 10.1016/J.Celrep.2015.07.044 |
0.561 |
|
2014 |
Kim HY, Kim HV, Yoon JH, Kang BR, Cho SM, Lee S, Kim JY, Kim JW, Cho Y, Woo J, Kim Y. Taurine in drinking water recovers learning and memory in the adult APP/PS1 mouse model of Alzheimer's disease. Scientific Reports. 4: 7467. PMID 25502280 DOI: 10.1038/srep07467 |
0.512 |
|
2014 |
Cho SM, Kim HV, Lee S, Kim HY, Kim W, Kim TS, Kim DJ, Kim Y. Correlations of amyloid-β concentrations between CSF and plasma in acute Alzheimer mouse model. Scientific Reports. 4: 6777. PMID 25345439 DOI: 10.1038/srep06777 |
0.567 |
|
2014 |
Jo S, Yarishkin O, Hwang YJ, Chun YE, Park M, Woo DH, Bae JY, Kim T, Lee J, Chun H, Park HJ, Lee da Y, Hong J, Kim HY, Oh SJ, et al. GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease. Nature Medicine. 20: 886-96. PMID 24973918 DOI: 10.1038/Nm.3639 |
0.427 |
|
2014 |
Lee HR, Shin HK, Park SY, Kim HY, Lee WS, Rhim BY, Hong KW, Kim CD. Cilostazol suppresses β-amyloid production by activating a disintegrin and metalloproteinase 10 via the upregulation of SIRT1-coupled retinoic acid receptor-β. Journal of Neuroscience Research. 92: 1581-90. PMID 24903973 DOI: 10.1002/jnr.23421 |
0.365 |
|
2014 |
Lee SH, Kim Y, Kim HY, Kim YH, Kim MS, Kong JY, Lee MH, Kim DJ, Ahn YG. Aminostyrylbenzofuran directly reduces oligomeric amyloid-β and reverses cognitive deficits in Alzheimer transgenic mice. Plos One. 9: e95733. PMID 24760018 DOI: 10.1371/Journal.Pone.0095733 |
0.533 |
|
2013 |
Lee YS, Kim HY, Youn HM, Seo JH, Kim Y, Shin KJ. 2-Phenylbenzofuran derivatives alleviate mitochondrial damage via the inhibition of β-amyloid aggregation. Bioorganic & Medicinal Chemistry Letters. 23: 5882-6. PMID 24076170 DOI: 10.1016/J.Bmcl.2013.08.087 |
0.476 |
|
2013 |
Byeon SR, Kim HV, Jeon M, Ahn YG, Kim MS, Kong JY, Kim HY, Kim YS, Kim DJ. Therapeutic and pharmacokinetic characterizations of an anti-amyloidogenic bis-styrylbenzene derivative for Alzheimer's disease treatment. Bioorganic & Medicinal Chemistry Letters. 23: 3467-9. PMID 23601707 DOI: 10.1016/J.Bmcl.2013.02.104 |
0.363 |
|
2013 |
Kim HV, Kim HY, Ehrlich HY, Choi SY, Kim DJ, Kim Y. Amelioration of Alzheimer's disease by neuroprotective effect of sulforaphane in animal model. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 20: 7-12. PMID 23253046 DOI: 10.3109/13506129.2012.751367 |
0.564 |
|
2012 |
Lee YS, Kim HY, Kim Y, Seo JH, Roh EJ, Han H, Shin KJ. Small molecules that protect against β-amyloid-induced cytotoxicity by inhibiting aggregation of β-amyloid. Bioorganic & Medicinal Chemistry. 20: 4921-35. PMID 22831802 DOI: 10.1016/J.Bmc.2012.06.045 |
0.577 |
|
2012 |
Choi JW, Kim HY, Jeon M, Kim DJ, Kim Y. Efficient access to highly pure β-amyloid peptide by optimized solid-phase synthesis. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 19: 133-7. PMID 22799493 DOI: 10.3109/13506129.2012.700287 |
0.475 |
|
2010 |
Kim HY, Kim Y, Han G, Kim DJ. Regulation of in vitro Aβ1-40 aggregation mediated by small molecules. Journal of Alzheimer's Disease : Jad. 22: 73-85. PMID 20847447 DOI: 10.3233/Jad-2010-100183 |
0.587 |
|
2010 |
Hong MC, Kim YK, Choi JY, Yang SQ, Rhee H, Ryu YH, Choi TH, Cheon GJ, An GI, Kim HY, Kim Y, Kim DJ, Lee JS, Chang YT, Lee KC. Synthesis and evaluation of stilbene derivatives as a potential imaging agent of amyloid plaques. Bioorganic & Medicinal Chemistry. 18: 7724-30. PMID 20621493 DOI: 10.1016/J.Bmc.2010.06.044 |
0.497 |
|
2007 |
Li Q, Min J, Ahn YH, Namm J, Kim EM, Lui R, Kim HY, Ji Y, Wu H, Wisniewski T, Chang YT. Styryl-based compounds as potential in vivo imaging agents for beta-amyloid plaques. Chembiochem : a European Journal of Chemical Biology. 8: 1679-87. PMID 17705341 DOI: 10.1002/Cbic.200700154 |
0.318 |
|
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