Hye Yun Kim - Publications

Affiliations: 
2010- Yonsei University, Seoul, South Korea 

48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 An J, Kim K, Lim HJ, Kim HY, Shin J, Park I, Cho I, Kim HY, Kim S, McLean C, Choi KY, Kim Y, Lee KH, Kim JS. Early onset diagnosis in Alzheimer's disease patients via amyloid-β oligomers-sensing probe in cerebrospinal fluid. Nature Communications. 15: 1004. PMID 38307843 DOI: 10.1038/s41467-024-44818-x  0.564
2023 Cha M, Dagar A, Lee S, Cho I, Lee D, Kim K, Park I, Yoon S, Kim HY, Kim I, Kim Y. Benzo[]imidazole-pyrrolo[1,2-]pyrazine Hybrids Ameliorate Amyloid Aggregates in the Brain of Alzheimer Transgenic Mice. Acs Chemical Neuroscience. PMID 37552840 DOI: 10.1021/acschemneuro.2c00547  0.598
2023 Lee D, Ryoo JE, Hong S, Kim HY, Kim Y. Carprofen alleviates Alzheimer-like phenotypes of 5XFAD transgenic mice by targeting the pathological hallmarks induced by amyloid-β aggregation. Scientific Reports. 13: 10889. PMID 37407605 DOI: 10.1038/s41598-023-36167-4  0.612
2023 Lee S, Dagar A, Cho I, Kim K, Park IW, Yoon S, Cha M, Shin J, Kim HY, Kim I, Kim Y. 4-Acyl-3,4-dihydropyrrolo[1,2-]pyrazine Derivative Rescued the Hippocampal-Dependent Cognitive Decline of 5XFAD Transgenic Mice by Dissociating Soluble and Insoluble Aβ Aggregates. Acs Chemical Neuroscience. PMID 37171100 DOI: 10.1021/acschemneuro.2c00788  0.607
2023 Kim HJ, Kim H, Park D, Yoon DS, San Lee J, Hwang KS. Plasma-based diagnostic and screening platform using a combination of biosensing signals in Alzheimer's disease. Biosensors & Bioelectronics. 230: 115246. PMID 37003061 DOI: 10.1016/j.bios.2023.115246  0.371
2023 Cui J, Ye S, Shin D, Cho I, Kim HY, Kwon Y, Park K, Nam SJ, Kim Y, Oh DC. Glycosylated and Succinylated Macrocyclic Lactones with Amyloid-β-Aggregation-Regulating Activity from a Marine sp. Marine Drugs. 21. PMID 36827108 DOI: 10.3390/md21020067  0.5
2023 Cho I, Lee H, Lee D, Park IW, Yoon S, Kim HY, Kim Y. Solid-phase synthesis and pathological evaluation of pyroglutamate amyloid-β peptide. Scientific Reports. 13: 505. PMID 36627316 DOI: 10.1038/s41598-022-26616-x  0.539
2022 Cho I, Yoon S, Park S, Hong SW, Cho E, Kim E, Kim HY, Kim Y. Immobilized Amyloid Hexamer Fragments to Map Active Sites of Amyloid-Targeting Chemicals. Acs Chemical Neuroscience. PMID 36445044 DOI: 10.1021/acschemneuro.2c00449  0.541
2022 Lee HY, Yoon S, Lee JH, Park K, Jung Y, Cho I, Lee D, Shin J, Kim K, Kim S, Kim J, Kim K, Han SH, Kim SM, Kim HJ, ... Kim HY, et al. Aryloxypropanolamine targets amyloid aggregates and reverses Alzheimer-like phenotypes in Alzheimer mouse models. Alzheimer's Research & Therapy. 14: 177. PMID 36443837 DOI: 10.1186/s13195-022-01112-6  0.49
2022 Lee H, Baek S, Cha M, Yang SH, Cho I, Shin H, Lee S, Kim HY, Lee S, Shin J, Lee D, Kim K, Park I, Yoon S, Kim J, ... ... Kim HJ, et al. Amyloid Against Amyloid: Dimeric Amyloid Fragment Ameliorates Cognitive Impairments by Direct Clearance of Oligomers and Plaques. Angewandte Chemie (International Ed. in English). PMID 36316282 DOI: 10.1002/anie.202210209  0.579
2022 Lee D, Kim HV, Kim HY, Kim Y. Chemical-Driven Outflow of Dissociated Amyloid Burden from Brain to Blood. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2104542. PMID 35106958 DOI: 10.1002/advs.202104542  0.583
2021 Kim K, Lee JH, Kim S, Lee S, Lee D, Kim HY, Kim I, Kim Y. Anti-amyloidogenic indolizino[3,2-]quinolines as imaging probes differentiating dense-core, diffuse, and coronal plaques of amyloid-β. Rsc Medicinal Chemistry. 12: 1926-1934. PMID 34825188 DOI: 10.1039/d1md00030f  0.565
2021 Kim HJ, Park D, Yun G, Kim H, Kim HG, Lee KM, Hong IK, Park KC, Lee JS, Hwang KS. Screening for cerebral amyloid angiopathy based on serological biomarkers analysis using a dielectrophoretic force-driven biosensor platform. Lab On a Chip. PMID 34724019 DOI: 10.1039/d1lc00742d  0.405
2021 Park S, Kim HY, Oh HA, Shin J, Park IW, Yoon S, Woo DH, Kim Y. Quinacrine directly dissociates amyloid plaques in the brain of 5XFAD transgenic mouse model of Alzheimer's disease. Scientific Reports. 11: 12043. PMID 34103615 DOI: 10.1038/s41598-021-91563-y  0.594
2021 Kim D, Lee JH, Kim HY, Shin J, Kim K, Lee S, Park J, Kim I, Kim Y. Correction: Fluorescent indolizine derivative YI-13 detects amyloid-β monomers, dimers, and plaques in the brain of 5XFAD Alzheimer transgenic mouse model. Plos One. 16: e0250194. PMID 33831134 DOI: 10.1371/journal.pone.0250194  0.488
2020 Kim D, Lee JH, Kim HY, Shin J, Kim K, Lee S, Park J, Kim J, Kim Y. Fluorescent indolizine derivative YI-13 detects amyloid-β monomers, dimers, and plaques in the brain of 5XFAD Alzheimer transgenic mouse model. Plos One. 15: e0243041. PMID 33362250 DOI: 10.1371/journal.pone.0243041  0.583
2020 Kim D, Bae GH, Kim HY, Jeon H, Kim K, Shin J, Lee S, Hong S, Kim I, Kim Y. Orally Administered Benzofuran Derivative Disaggregated Aβ Plaques and Oligomers in the Brain of 5XFAD Alzheimer Transgenic Mouse. Acs Chemical Neuroscience. PMID 33332107 DOI: 10.1021/acschemneuro.0c00606  0.613
2020 Kim HY, Lee H, Lee JK, Kim HV, Kim KS, Kim Y. Bicine promotes rapid formation of β-sheet-rich amyloid-β fibrils. Plos One. 15: e0240608. PMID 33048999 DOI: 10.1371/journal.pone.0240608  0.553
2020 Lee JC, Kim HY, Lee S, Shin J, Kim HV, Kim K, Baek S, Lee D, Jeon H, Kim D, Yang SH, Han G, Park K, Choi J, Park J, et al. Discovery of chemicals to clear or indicate amyloid aggregates by targeting memory-impairing anti-parallel Aβ dimers. Angewandte Chemie (International Ed. in English). PMID 32233096 DOI: 10.1002/Anie.202002574  0.596
2020 Heo JY, Nam MH, Yoon HH, Kim J, Hwang YJ, Won W, Woo DH, Lee JA, Park HJ, Jo S, Lee MJ, Kim S, Shim JE, Jang DP, Kim KI, ... ... Kim HY, et al. Aberrant Tonic Inhibition of Dopaminergic Neuronal Activity Causes Motor Symptoms in Animal Models of Parkinson's Disease. Current Biology : Cb. PMID 31928877 DOI: 10.1016/J.Cub.2019.11.079  0.312
2020 Kwak DE, Ko T, Koh HS, Ji YW, Shin J, Kim K, Kim HY, Lee HK, Kim Y. Alterations of aqueous humor Aβ levels in Aβ-infused and transgenic mouse models of Alzheimer disease. Plos One. 15: e0227618. PMID 31923257 DOI: 10.1371/Journal.Pone.0227618  0.582
2019 Lee H, Kim D, Lee W, Kim HY, Kim Y. Preventive approach for overcoming dementia. Archives of Pharmacal Research. PMID 31187441 DOI: 10.1007/S12272-019-01168-3  0.402
2019 Lee D, Kim SM, Kim HY, Kim Y. Fluorescence chemicals to detect insoluble and soluble amyloid-β aggregates. Acs Chemical Neuroscience. PMID 31009195 DOI: 10.1021/Acschemneuro.9B00199  0.574
2019 Kim Y, Yoo YK, Kim HY, Roh JH, Kim J, Baek S, Lee JC, Kim HJ, Chae MS, Jeong D, Park D, Lee S, Jang H, Kim K, Lee JH, et al. Comparative analyses of plasma amyloid-β levels in heterogeneous and monomerized states by interdigitated microelectrode sensor system. Science Advances. 5: eaav1388. PMID 31001580 DOI: 10.1126/Sciadv.Aav1388  0.56
2018 Shim HG, Jang SS, Kim SH, Hwang EM, Min JO, Kim HY, Kim YS, Ryu C, Chung G, Kim Y, Yoon BE, Kim SJ. TNF-α increases the intrinsic excitability of cerebellar Purkinje cells through elevating glutamate release in Bergmann Glia. Scientific Reports. 8: 11589. PMID 30072733 DOI: 10.1038/S41598-018-29786-9  0.329
2017 Jang H, Lee S, Choi SL, Kim HY, Baek S, Kim Y. Taurine Directly Binds to Oligomeric Amyloid-β and Recovers Cognitive Deficits in Alzheimer Model Mice. Advances in Experimental Medicine and Biology. 975: 233-241. PMID 28849459 DOI: 10.1007/978-94-024-1079-2_21  0.549
2017 Kim HY, Yang SH, Yoon J, Jang H, Baek S, Shin J, Kim SH, Kim Y. Taurine-Carbohydrate Derivative Stimulates Fibrillogenesis of Amyloid-β and Reduce Alzheimer-Like Behaviors. Advances in Experimental Medicine and Biology. 975: 225-232. PMID 28849458 DOI: 10.1007/978-94-024-1079-2_20  0.611
2017 Yoo YK, Kim J, Kim G, Kim YS, Kim HY, Lee S, Cho WW, Kim S, Lee SM, Lee BC, Lee JH, Hwang KS. A highly sensitive plasma-based amyloid-β detection system through medium-changing and noise cancellation system for early diagnosis of the Alzheimer's disease. Scientific Reports. 7: 8882. PMID 28827785 DOI: 10.1038/S41598-017-09370-3  0.336
2017 Kim HY, Lee D, Ryu KY, Choi I. A gold nanoparticle-mediated rapid in vitro assay of anti-aggregation reagents for amyloid β and its validation. Chemical Communications (Cambridge, England). PMID 28338146 DOI: 10.1039/c7cc00358g  0.319
2016 Kim HY, Kim HV, Lee DK, Yang SH, Kim Y. Rapid and sustained cognitive recovery in APP/PS1 transgenic mice by co-administration of EPPS and donepezil. Scientific Reports. 6: 34165. PMID 27796293 DOI: 10.1038/Srep34165  0.554
2016 Kim HY, Lee DK, Chung BR, Kim HV, Kim Y. Intracerebroventricular Injection of Amyloid-β Peptides in Normal Mice to Acutely Induce Alzheimer-like Cognitive Deficits. Journal of Visualized Experiments : Jove. PMID 27023127 DOI: 10.3791/53308  0.591
2016 Kim HY, Kim HV, Jo S, Lee CJ, Choi SY, Kim DJ, Kim Y. Corrigendum: EPPS rescues hippocampus-dependent cognitive deficits in APP/PS1 mice by disaggregation of amyloid-β oligomers and plaques. Nature Communications. 7: 10755. PMID 26877163 DOI: 10.1038/Ncomms10755  0.428
2016 Cho SM, Lee S, Yang SH, Kim HY, Lee MJ, Kim HV, Kim J, Baek S, Yun J, Kim D, Kim YK, Cho Y, Woo J, Kim TS, Kim Y. Age-dependent inverse correlations in CSF and plasma amyloid-β(1-42) concentrations prior to amyloid plaque deposition in the brain of 3xTg-AD mice. Scientific Reports. 6: 20185. PMID 26830653 DOI: 10.1038/Srep20185  0.565
2015 Kim HY, Kim HV, Jo S, Lee CJ, Choi SY, Kim DJ, Kim Y. EPPS rescues hippocampus-dependent cognitive deficits in APP/PS1 mice by disaggregation of amyloid-β oligomers and plaques. Nature Communications. 6: 8997. PMID 26646366 DOI: 10.1038/Ncomms9997  0.612
2015 Yang Y, Kim J, Kim HY, Ryoo N, Lee S, Kim Y, Rhim H, Shin YK. Amyloid-β Oligomers May Impair SNARE-Mediated Exocytosis by Direct Binding to Syntaxin 1a. Cell Reports. PMID 26279571 DOI: 10.1016/J.Celrep.2015.07.044  0.561
2014 Kim HY, Kim HV, Yoon JH, Kang BR, Cho SM, Lee S, Kim JY, Kim JW, Cho Y, Woo J, Kim Y. Taurine in drinking water recovers learning and memory in the adult APP/PS1 mouse model of Alzheimer's disease. Scientific Reports. 4: 7467. PMID 25502280 DOI: 10.1038/srep07467  0.512
2014 Cho SM, Kim HV, Lee S, Kim HY, Kim W, Kim TS, Kim DJ, Kim Y. Correlations of amyloid-β concentrations between CSF and plasma in acute Alzheimer mouse model. Scientific Reports. 4: 6777. PMID 25345439 DOI: 10.1038/srep06777  0.567
2014 Jo S, Yarishkin O, Hwang YJ, Chun YE, Park M, Woo DH, Bae JY, Kim T, Lee J, Chun H, Park HJ, Lee da Y, Hong J, Kim HY, Oh SJ, et al. GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease. Nature Medicine. 20: 886-96. PMID 24973918 DOI: 10.1038/Nm.3639  0.427
2014 Lee HR, Shin HK, Park SY, Kim HY, Lee WS, Rhim BY, Hong KW, Kim CD. Cilostazol suppresses β-amyloid production by activating a disintegrin and metalloproteinase 10 via the upregulation of SIRT1-coupled retinoic acid receptor-β. Journal of Neuroscience Research. 92: 1581-90. PMID 24903973 DOI: 10.1002/jnr.23421  0.365
2014 Lee SH, Kim Y, Kim HY, Kim YH, Kim MS, Kong JY, Lee MH, Kim DJ, Ahn YG. Aminostyrylbenzofuran directly reduces oligomeric amyloid-β and reverses cognitive deficits in Alzheimer transgenic mice. Plos One. 9: e95733. PMID 24760018 DOI: 10.1371/Journal.Pone.0095733  0.533
2013 Lee YS, Kim HY, Youn HM, Seo JH, Kim Y, Shin KJ. 2-Phenylbenzofuran derivatives alleviate mitochondrial damage via the inhibition of β-amyloid aggregation. Bioorganic & Medicinal Chemistry Letters. 23: 5882-6. PMID 24076170 DOI: 10.1016/J.Bmcl.2013.08.087  0.476
2013 Byeon SR, Kim HV, Jeon M, Ahn YG, Kim MS, Kong JY, Kim HY, Kim YS, Kim DJ. Therapeutic and pharmacokinetic characterizations of an anti-amyloidogenic bis-styrylbenzene derivative for Alzheimer's disease treatment. Bioorganic & Medicinal Chemistry Letters. 23: 3467-9. PMID 23601707 DOI: 10.1016/J.Bmcl.2013.02.104  0.363
2013 Kim HV, Kim HY, Ehrlich HY, Choi SY, Kim DJ, Kim Y. Amelioration of Alzheimer's disease by neuroprotective effect of sulforaphane in animal model. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 20: 7-12. PMID 23253046 DOI: 10.3109/13506129.2012.751367  0.564
2012 Lee YS, Kim HY, Kim Y, Seo JH, Roh EJ, Han H, Shin KJ. Small molecules that protect against β-amyloid-induced cytotoxicity by inhibiting aggregation of β-amyloid. Bioorganic & Medicinal Chemistry. 20: 4921-35. PMID 22831802 DOI: 10.1016/J.Bmc.2012.06.045  0.577
2012 Choi JW, Kim HY, Jeon M, Kim DJ, Kim Y. Efficient access to highly pure β-amyloid peptide by optimized solid-phase synthesis. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 19: 133-7. PMID 22799493 DOI: 10.3109/13506129.2012.700287  0.475
2010 Kim HY, Kim Y, Han G, Kim DJ. Regulation of in vitro Aβ1-40 aggregation mediated by small molecules. Journal of Alzheimer's Disease : Jad. 22: 73-85. PMID 20847447 DOI: 10.3233/Jad-2010-100183  0.587
2010 Hong MC, Kim YK, Choi JY, Yang SQ, Rhee H, Ryu YH, Choi TH, Cheon GJ, An GI, Kim HY, Kim Y, Kim DJ, Lee JS, Chang YT, Lee KC. Synthesis and evaluation of stilbene derivatives as a potential imaging agent of amyloid plaques. Bioorganic & Medicinal Chemistry. 18: 7724-30. PMID 20621493 DOI: 10.1016/J.Bmc.2010.06.044  0.497
2007 Li Q, Min J, Ahn YH, Namm J, Kim EM, Lui R, Kim HY, Ji Y, Wu H, Wisniewski T, Chang YT. Styryl-based compounds as potential in vivo imaging agents for beta-amyloid plaques. Chembiochem : a European Journal of Chemical Biology. 8: 1679-87. PMID 17705341 DOI: 10.1002/Cbic.200700154  0.318
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