| Year |
Citation |
Score |
| 2023 |
Maroto IB, Costas-Insua C, Berthoux C, Moreno E, Ruiz-Calvo A, Montero-Fernández C, Macías-Camero A, Martín R, García-Font N, Sánchez-Prieto J, Marsicano G, Bellocchio L, Canela EI, Casadó V, Galve-Roperh I, et al. Control of a hippocampal recurrent excitatory circuit by cannabinoid receptor-interacting protein Gap43. Nature Communications. 14: 2303. PMID 37085487 DOI: 10.1038/s41467-023-38026-2 |
0.42 |
|
| 2021 |
Costas-Insua C, Moreno E, Maroto IB, Ruiz-Calvo A, Bajo-Grañeras R, Martín-Gutiérrez D, Diez-Alarcia R, Vilaró MT, Cortés R, García-Font N, Martín R, Espina M, Botta J, Ginés S, McCormick PJ, ... ... Canela EI, et al. Identification of BiP as a CB receptor-interacting protein that fine-tunes cannabinoid signaling in the mouse brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 34353897 DOI: 10.1523/JNEUROSCI.0821-21.2021 |
0.433 |
|
| 2021 |
Casadó-Anguera V, Moreno E, Sánchez-Soto M, Cai NS, Bonaventura J, Homar-Ruano P, Rubinstein M, Cortés A, Canela EI, Ferré S, Casadó V. Heteromerization between α adrenoceptors and different polymorphic variants of the dopamine D receptor determines pharmacological and functional differences. Implications for impulsive-control disorders. Pharmacological Research. 105745. PMID 34182128 DOI: 10.1016/j.phrs.2021.105745 |
0.383 |
|
| 2021 |
Moreno E, Cavic M, Canela EI. Functional Fine-Tuning of Metabolic Pathways by the Endocannabinoid System-Implications for Health and Disease. International Journal of Molecular Sciences. 22. PMID 33915889 DOI: 10.3390/ijms22073661 |
0.322 |
|
| 2020 |
Moreno-Delgado D, Puigdellívol M, Moreno E, Rodríguez-Ruiz M, Botta J, Gasperini P, Chiarlone A, Howell LA, Scarselli M, Casadó V, Cortés A, Ferré S, Guzmán M, Lluís C, Alberch J, ... Canela EI, et al. Modulation of dopamine D receptors via histamine H receptors is a novel therapeutic target for Huntington's disease. Elife. 9. PMID 32513388 DOI: 10.7554/Elife.51093 |
0.411 |
|
| 2020 |
Franco R, Castelló J, Canela EI. The Kinetic Component in Drug Discovery: Using the Most Basic Pharmacological Concepts to Advance in Selecting Drugs to Combat CNS Diseases. Current Neuropharmacology. 18: 250-257. PMID 31573886 DOI: 10.2174/1570159X17666191001144309 |
0.348 |
|
| 2019 |
Franco R, Reyes-Resina I, Aguinaga D, Lillo A, Jiménez J, Raïch I, Borroto-Escuela DO, Ferreiro-Vera C, Canela EI, Sánchez de Medina V, Del Ser-Badia A, Fuxe K, Saura CA, Navarro G. Potentiation of cannabinoid signaling in microglia by adenosine A receptor antagonists. Glia. PMID 31429130 DOI: 10.1002/Glia.23694 |
0.399 |
|
| 2019 |
Moreno E, Cavic M, Krivokuca A, Casadó V, Canela E. The Endocannabinoid System as a Target in Cancer Diseases: Are We There Yet? Frontiers in Pharmacology. 10: 339. PMID 31024307 DOI: 10.3389/fphar.2019.00339 |
0.436 |
|
| 2019 |
Guitart X, Moreno E, Rea W, Sánchez-Soto M, Cai NS, Quiroz C, Kumar V, Bourque L, Cortés A, Canela EI, Bishop C, Newman AH, Casadó V, Ferré S. Biased G Protein-Independent Signaling of Dopamine D-D Receptor Heteromers in the Nucleus Accumbens. Molecular Neurobiology. PMID 30919214 DOI: 10.1007/S12035-019-1564-8 |
0.387 |
|
| 2018 |
Casadó-Anguera V, Moreno E, Mallol J, Ferré S, Canela EI, Cortés A, Casadó V. Reinterpreting anomalous competitive binding experiments within G protein-coupled receptor homodimers using a dimer receptor model. Pharmacological Research. 139: 337-347. PMID 30472462 DOI: 10.1016/j.phrs.2018.11.032 |
0.477 |
|
| 2018 |
Navarro G, Medrano M, Aguinaga D, Vega-Quiroga I, Lillo A, Jiménez J, Casanovas M, Canela EI, Mallol J, Gysling K, Franco R. Differential effect of amphetamine over the corticotropin-releasing factor CRF receptor, the orexin OX receptor and the CRF-OX heteroreceptor complex. Neuropharmacology. PMID 30465812 DOI: 10.1016/j.neuropharm.2018.11.014 |
0.627 |
|
| 2018 |
Franco R, Aguinaga D, Reyes I, Canela EI, Lillo J, Tarutani A, Hasegawa M, Del Ser-Badia A, Del Rio JA, Kreutz MR, Saura CA, Navarro G. -Methyl-D-Aspartate Receptor Link to the MAP Kinase Pathway in Cortical and Hippocampal Neurons and Microglia Is Dependent on Calcium Sensors and Is Blocked by α-Synuclein, Tau, and Phospho-Tau in Non-transgenic and Transgenic APP Mice. Frontiers in Molecular Neuroscience. 11: 273. PMID 30233307 DOI: 10.3389/fnmol.2018.00273 |
0.314 |
|
| 2018 |
Navarro G, Varani K, Reyes-Resina I, Sánchez de Medina V, Rivas-Santisteban R, Sánchez-Carnerero Callado C, Vincenzi F, Casano S, Ferreiro-Vera C, Canela EI, Borea PA, Nadal X, Franco R. Cannabigerol Action at Cannabinoid CB and CB Receptors and at CB-CB Heteroreceptor Complexes. Frontiers in Pharmacology. 9: 632. PMID 29977202 DOI: 10.3389/fphar.2018.00632 |
0.565 |
|
| 2018 |
Aguinaga D, Medrano M, Cordomí A, Jiménez-Rosés M, Angelats E, Casanovas M, Vega-Quiroga I, Canela EI, Petrovic M, Gysling K, Pardo L, Franco R, Navarro G. Cocaine Blocks Effects of Hunger Hormone, Ghrelin, Via Interaction with Neuronal Sigma-1 Receptors. Molecular Neurobiology. PMID 29876881 DOI: 10.1007/s12035-018-1140-7 |
0.339 |
|
| 2018 |
Reyes-Resina I, Navarro G, Aguinaga D, Canela EI, Schoeder CT, Zaluski M, Kiec-Kononowicz K, Saura CA, Müller CE, Franco R. Molecular and functional interaction between GPR18 and cannabinoid CB G-protein-coupled receptors. Relevance in neurodegenerative diseases. Biochemical Pharmacology. PMID 29870711 DOI: 10.1016/J.Bcp.2018.06.001 |
0.62 |
|
| 2018 |
Rivera-Oliver M, Moreno E, Álvarez-Bagnarol Y, Ayala-Santiago C, Cruz-Reyes N, Molina-Castro GC, Clemens S, Canela EI, Ferré S, Casadó V, Díaz-Ríos M. Adenosine A-Dopamine D Receptor Heteromers Control the Excitability of the Spinal Motoneuron. Molecular Neurobiology. PMID 29797183 DOI: 10.1007/S12035-018-1120-Y |
0.338 |
|
| 2018 |
Navarro G, Cordomí A, Casadó-Anguera V, Moreno E, Cai NS, Cortés A, Canela EI, Dessauer CW, Casadó V, Pardo L, Lluís C, Ferré S. Evidence for functional pre-coupled complexes of receptor heteromers and adenylyl cyclase. Nature Communications. 9: 1242. PMID 29593213 DOI: 10.1038/S41467-018-03522-3 |
0.404 |
|
| 2018 |
Sánchez-Soto M, Casadó-Anguera V, Yano H, Bender BJ, Cai NS, Moreno E, Canela EI, Cortés A, Meiler J, Casadó V, Ferré S. α- and α-Adrenoceptors as Potential Targets for Dopamine and Dopamine Receptor Ligands. Molecular Neurobiology. PMID 29552726 DOI: 10.1007/S12035-018-1004-1 |
0.371 |
|
| 2018 |
Moreno E, Canet J, Gracia E, Lluís C, Mallol J, Canela EI, Cortés A, Casadó V. Molecular Evidence of Adenosine Deaminase Linking Adenosine A Receptor and CD26 Proteins. Frontiers in Pharmacology. 9: 106. PMID 29497379 DOI: 10.3389/fphar.2018.00106 |
0.371 |
|
| 2018 |
Navarro G, Cordomí A, Brugarolas M, Moreno E, Aguinaga D, Pérez-Benito L, Ferre S, Cortés A, Casadó V, Mallol J, Canela EI, Lluís C, Pardo L, McCormick PJ, Franco R. Cross-communication between Gand Gin a G-protein-coupled receptor heterotetramer guided by a receptor C-terminal domain. Bmc Biology. 16: 24. PMID 29486745 DOI: 10.1186/S12915-018-0491-X |
0.57 |
|
| 2018 |
Aguinaga D, Medrano M, Vega-Quiroga I, Gysling K, Canela EI, Navarro G, Franco R. Cocaine Effects on Dopaminergic Transmission Depend on a Balance between Sigma-1 and Sigma-2 Receptor Expression. Frontiers in Molecular Neuroscience. 11: 17. PMID 29483862 DOI: 10.3389/fnmol.2018.00017 |
0.315 |
|
| 2017 |
Martínez-Pinilla E, Varani K, Reyes-Resina I, Angelats E, Vincenzi F, Ferreiro-Vera C, Oyarzabal J, Canela EI, Lanciego JL, Nadal X, Navarro G, Borea PA, Franco R. Binding and Signaling Studies Disclose a Potential Allosteric Site for Cannabidiol in Cannabinoid CB2 Receptors. Frontiers in Pharmacology. 8: 744. PMID 29109685 DOI: 10.3389/fphar.2017.00744 |
0.409 |
|
| 2017 |
Navarro G, Borroto-Escuela D, Angelats E, Etayo Í, Reyes-Resina I, Pulido-Salgado M, Rodriguez-Perez AI, Canela EI, Saura J, Lanciego JL, Labandeira-García JL, Saura CA, Fuxe K, Franco R. Receptor-heteromer mediated regulation of endocannabinoid signaling in activated microglia. Role of CB1 and CB2 receptors and relevance for Alzheimer's disease and levodopa-induced dyskinesia. Brain, Behavior, and Immunity. PMID 28843453 DOI: 10.1016/J.Bbi.2017.08.015 |
0.475 |
|
| 2017 |
Medrano M, Aguinaga D, Reyes-Resina I, Canela EI, Mallol J, Navarro G, Franco R. Orexin A/Hypocretin Modulates Leptin Receptor-Mediated Signaling by Allosteric Modulations Mediated by the Ghrelin GHS-R1A Receptor in Hypothalamic Neurons. Molecular Neurobiology. PMID 28717967 DOI: 10.1007/s12035-017-0670-8 |
0.518 |
|
| 2017 |
Moreno E, Chiarlone A, Medrano M, Puigdellívol M, Bibic L, Howell LA, Resel E, Puente N, Casarejos MJ, Perucho J, Botta J, Suelves N, Ciruela F, Ginés S, Galve-Roperh I, ... ... Canela EI, et al. Singular Location and Signaling Profile of Adenosine A2A-Cannabinoid CB1 Receptor Heteromers in the Dorsal Striatum. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28102227 DOI: 10.1038/Npp.2017.12 |
0.663 |
|
| 2016 |
Moreno E, Quiroz C, Rea W, Cai NS, Mallol J, Cortés A, Lluís C, Canela EI, Casadó V, Ferré S. Functional μ-opioid-galanin receptor heteromers in the ventral tegmental area. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28007761 DOI: 10.1523/JNEUROSCI.2442-16.2016 |
0.395 |
|
| 2016 |
Rodríguez-Ruiz M, Moreno E, Moreno-Delgado D, Navarro G, Mallol J, Cortés A, Lluís C, Canela EI, Casadó V, McCormick PJ, Franco R. Heteroreceptor Complexes Formed by Dopamine D1, Histamine H3, and N-Methyl-D-Aspartate Glutamate Receptors as Targets to Prevent Neuronal Death in Alzheimer's Disease. Molecular Neurobiology. PMID 27370794 DOI: 10.1007/S12035-016-9995-Y |
0.552 |
|
| 2016 |
Cortés A, Moreno E, Rodríguez-Ruiz M, Canela EI, Casadó V. Targeting the dopamine D3 receptor: an overview of drug design strategies. Expert Opinion On Drug Discovery. 11: 641-64. PMID 27135354 DOI: 10.1080/17460441.2016.1185413 |
0.412 |
|
| 2016 |
Brugal G, Aguinaga D, Angelats E, Medrano M, Moreno E, Mallol J, Cortés A, Canela EI, Casadó V, McCormick PJ, Lluís C, Ferré S. Significant Role of the Truncated Ghrelin Receptor GHS-1Rb in Ghrelin-Induced Signaling in Neurons. The Journal of Biological Chemistry. PMID 27129257 DOI: 10.1074/Jbc.M116.715144 |
0.311 |
|
| 2016 |
Navarro G, Cordomí A, Zelman-Femiak M, Brugarolas M, Moreno E, Aguinaga D, Perez-Benito L, Cortés A, Casadó V, Mallol J, Canela EI, Lluís C, Pardo L, García-Sáez AJ, McCormick PJ, et al. Quaternary structure of a G-protein-coupled receptor heterotetramer in complex with Gi and Gs. Bmc Biology. 14: 26. PMID 27048449 DOI: 10.1186/S12915-016-0247-4 |
0.444 |
|
| 2015 |
Viñals X, Moreno E, Lanfumey L, Cordomí A, Pastor A, de La Torre R, Gasperini P, Navarro G, Howell LA, Pardo L, Lluís C, Canela EI, McCormick PJ, Maldonado R, Robledo P. Cognitive Impairment Induced by Delta9-tetrahydrocannabinol Occurs through Heteromers between Cannabinoid CB1 and Serotonin 5-HT2A Receptors. Plos Biology. 13: e1002194. PMID 26158621 DOI: 10.1371/Journal.Pbio.1002194 |
0.507 |
|
| 2015 |
Bonaventura J, Navarro G, Casadó-Anguera V, Azdad K, Rea W, Moreno E, Brugarolas M, Mallol J, Canela EI, Lluís C, Cortés A, Volkow ND, Schiffmann SN, Ferré S, Casadó V. Allosteric interactions between agonists and antagonists within the adenosine A2A receptor-dopamine D2 receptor heterotetramer. Proceedings of the National Academy of Sciences of the United States of America. 112: E3609-18. PMID 26100888 DOI: 10.1073/pnas.1507704112 |
0.575 |
|
| 2015 |
Pérez-Gómez E, Andradas C, Blasco-Benito S, Caffarel MM, García-Taboada E, Villa-Morales M, Moreno E, Hamann S, Martín-Villar E, Flores JM, Wenners A, Alkatout I, Klapper W, Röcken C, Bronsert P, ... ... Canela EI, et al. Role of cannabinoid receptor CB2 in HER2 pro-oncogenic signaling in breast cancer. Journal of the National Cancer Institute. 107: djv077. PMID 25855725 DOI: 10.1093/Jnci/Djv077 |
0.396 |
|
| 2015 |
Cortés A, Gracia E, Moreno E, Mallol J, Lluís C, Canela EI, Casadó V. Moonlighting adenosine deaminase: a target protein for drug development. Medicinal Research Reviews. 35: 85-125. PMID 24933472 DOI: 10.1002/med.21324 |
0.392 |
|
| 2014 |
Navarro G, Aguinaga D, Moreno E, Hradsky J, Reddy PP, Cortés A, Mallol J, Casadó V, Mikhaylova M, Kreutz MR, Lluís C, Canela EI, McCormick PJ, Ferré S. Intracellular calcium levels determine differential modulation of allosteric interactions within G protein-coupled receptor heteromers. Chemistry & Biology. 21: 1546-56. PMID 25457181 DOI: 10.1016/J.Chembiol.2014.10.004 |
0.428 |
|
| 2014 |
Farré D, Muñoz A, Moreno E, Reyes-Resina I, Canet-Pons J, Dopeso-Reyes IG, Rico AJ, Lluís C, Mallol J, Navarro G, Canela EI, Cortés A, Labandeira-García JL, Casadó V, Lanciego JL, et al. Stronger Dopamine D1 Receptor-Mediated Neurotransmission in Dyskinesia. Molecular Neurobiology. PMID 25344317 DOI: 10.1007/s12035-014-8936-x |
0.466 |
|
| 2014 |
Guitart X, Navarro G, Moreno E, Yano H, Cai NS, Sánchez-Soto M, Kumar-Barodia S, Naidu YT, Mallol J, Cortés A, Lluís C, Canela EI, Casadó V, McCormick PJ, Ferré S. Functional selectivity of allosteric interactions within G protein-coupled receptor oligomers: the dopamine D1-D3 receptor heterotetramer. Molecular Pharmacology. 86: 417-29. PMID 25097189 DOI: 10.1124/Mol.114.093096 |
0.536 |
|
| 2014 |
Moreno E, Andradas C, Medrano M, Caffarel MM, Pérez-Gómez E, Blasco-Benito S, Gómez-Cañas M, Pazos MR, Irving AJ, Lluís C, Canela EI, Fernández-Ruiz J, Guzmán M, McCormick PJ, Sánchez C. Targeting CB2-GPR55 receptor heteromers modulates cancer cell signaling. The Journal of Biological Chemistry. 289: 21960-72. PMID 24942731 DOI: 10.1074/Jbc.M114.561761 |
0.41 |
|
| 2014 |
Moreno E, Moreno-Delgado D, Navarro G, Hoffmann HM, Fuentes S, Rosell-Vilar S, Gasperini P, Rodríguez-Ruiz M, Medrano M, Mallol J, Cortés A, Casadó V, Lluís C, Ferré S, Ortiz J, ... Canela E, et al. Cocaine disrupts histamine H3 receptor modulation of dopamine D1 receptor signaling: σ1-D1-H3 receptor complexes as key targets for reducing cocaine's effects. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 3545-58. PMID 24599455 DOI: 10.1523/JNEUROSCI.4147-13.2014 |
0.499 |
|
| 2014 |
Pinna A, Bonaventura J, Farré D, Sánchez M, Simola N, Mallol J, Lluís C, Costa G, Baqi Y, Müller CE, Cortés A, McCormick P, Canela EI, Martínez-Pinilla E, Lanciego JL, et al. L-DOPA disrupts adenosine A(2A)-cannabinoid CB(1)-dopamine D(2) receptor heteromer cross-talk in the striatum of hemiparkinsonian rats: biochemical and behavioral studies. Experimental Neurology. 253: 180-91. PMID 24412491 DOI: 10.1016/J.Expneurol.2013.12.021 |
0.476 |
|
| 2014 |
Bonaventura J, Rico AJ, Moreno E, Sierra S, Sánchez M, Luquin N, Farré D, Müller CE, Martínez-Pinilla E, Cortés A, Mallol J, Armentero MT, Pinna A, Canela EI, Lluís C, et al. L-DOPA-treatment in primates disrupts the expression of A(2A) adenosine-CB(1) cannabinoid-D(2) dopamine receptor heteromers in the caudate nucleus. Neuropharmacology. 79: 90-100. PMID 24230991 DOI: 10.1016/J.Neuropharm.2013.10.036 |
0.428 |
|
| 2013 |
Navarro G, Moreno E, Bonaventura J, Brugarolas M, Farré D, Aguinaga D, Mallol J, Cortés A, Casadó V, Lluís C, Ferre S, Franco R, Canela E, McCormick PJ. Cocaine inhibits dopamine D2 receptor signaling via sigma-1-D2 receptor heteromers. Plos One. 8: e61245. PMID 23637801 DOI: 10.1371/Journal.Pone.0061245 |
0.485 |
|
| 2013 |
Gracia E, Moreno E, Cortés A, Lluís C, Mallol J, McCormick PJ, Canela EI, Casadó V. Homodimerization of adenosine A₁ receptors in brain cortex explains the biphasic effects of caffeine. Neuropharmacology. 71: 56-69. PMID 23523559 DOI: 10.1016/J.Neuropharm.2013.03.005 |
0.493 |
|
| 2013 |
Navarro G, McCormick PJ, Mallol J, Lluís C, Franco R, Cortés A, Casadó V, Canela EI, Ferré S. Detection of receptor heteromers involving dopamine receptors by the sequential BRET-FRET technology. Methods in Molecular Biology (Clifton, N.J.). 964: 95-105. PMID 23296780 DOI: 10.1007/978-1-62703-251-3_7 |
0.633 |
|
| 2013 |
Gracia E, Farré D, Cortés A, Ferrer-Costa C, Orozco M, Mallol J, Lluís C, Canela EI, McCormick PJ, Franco R, Fanelli F, Casadó V. The catalytic site structural gate of adenosine deaminase allosterically modulates ligand binding to adenosine receptors. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 1048-61. PMID 23193172 DOI: 10.1096/Fj.12-212621 |
0.463 |
|
| 2012 |
Canela L, Selga E, GarcÃa-MartÃnez JM, Amaral OB, Fernández-Dueñas V, Alberch J, Canela EI, Franco R, Noé V, LluÃs C, Ciudad CJ, Ciruela F. Transcriptional profiling of striatal neurons in response to single or concurrent activation of dopamine D2, adenosine A(2A) and metabotropic glutamate type 5 receptors: focus on beta-synuclein expression. Gene. 508: 199-205. PMID 22892378 DOI: 10.1016/J.Gene.2012.07.074 |
0.719 |
|
| 2012 |
González S, Moreno-Delgado D, Moreno E, Pérez-Capote K, Franco R, Mallol J, Cortés A, Casadó V, Lluís C, Ortiz J, Ferré S, Canela E, McCormick PJ. Circadian-related heteromerization of adrenergic and dopamine D₄ receptors modulates melatonin synthesis and release in the pineal gland. Plos Biology. 10: e1001347. PMID 22723743 DOI: 10.1371/Journal.Pbio.1001347 |
0.489 |
|
| 2012 |
Callén L, Moreno E, Barroso-Chinea P, Moreno-Delgado D, Cortés A, Mallol J, Casadó V, Lanciego JL, Franco R, Lluis C, Canela EI, McCormick PJ. Cannabinoid receptors CB1 and CB2 form functional heteromers in brain. The Journal of Biological Chemistry. 287: 20851-65. PMID 22532560 DOI: 10.1074/Jbc.M111.335273 |
0.638 |
|
| 2011 |
Ferré S, Quiroz C, Orru M, Guitart X, Navarro G, Cortés A, Casadó V, Canela EI, Lluis C, Franco R. Adenosine A(2A) Receptors and A(2A) Receptor Heteromers as Key Players in Striatal Function. Frontiers in Neuroanatomy. 5: 36. PMID 21731559 DOI: 10.3389/fnana.2011.00036 |
0.358 |
|
| 2011 |
Cavić M, Lluís C, Moreno E, Bakešová J, Canela EI, Navarro G. Production of functional recombinant G-protein coupled receptors for heteromerization studies. Journal of Neuroscience Methods. 199: 258-64. PMID 21658412 DOI: 10.1016/j.jneumeth.2011.05.021 |
0.637 |
|
| 2011 |
Moreno E, Vaz SH, Cai NS, Ferrada C, Quiroz C, Barodia SK, Kabbani N, Canela EI, McCormick PJ, Lluis C, Franco R, Ribeiro JA, Sebastião AM, Ferré S. Dopamine-galanin receptor heteromers modulate cholinergic neurotransmission in the rat ventral hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 7412-23. PMID 21593325 DOI: 10.1523/Jneurosci.0191-11.2011 |
0.574 |
|
| 2011 |
Gracia E, Pérez-Capote K, Moreno E, Barkešová J, Mallol J, Lluís C, Franco R, Cortés A, Casadó V, Canela EI. A2A adenosine receptor ligand binding and signalling is allosterically modulated by adenosine deaminase. The Biochemical Journal. 435: 701-9. PMID 21306300 DOI: 10.1042/BJ20101749 |
0.556 |
|
| 2011 |
Moreno E, Hoffmann H, Gonzalez-Sepúlveda M, Navarro G, Casadó V, Cortés A, Mallol J, Vignes M, McCormick PJ, Canela EI, LluÃs C, Moratalla R, Ferré S, Ortiz J, Franco R. Dopamine D1-histamine H3 receptor heteromers provide a selective link to MAPK signaling in GABAergic neurons of the direct striatal pathway. The Journal of Biological Chemistry. 286: 5846-54. PMID 21173143 DOI: 10.1074/Jbc.M110.161489 |
0.545 |
|
| 2010 |
Ferré S, Navarro G, Casadó V, Cortés A, Mallol J, Canela EI, Lluís C, Franco R. G protein-coupled receptor heteromers as new targets for drug development. Progress in Molecular Biology and Translational Science. 91: 41-52. PMID 20691958 DOI: 10.1016/S1877-1173(10)91002-8 |
0.495 |
|
| 2010 |
Ferré S, Lluís C, Justinova Z, Quiroz C, Orru M, Navarro G, Canela EI, Franco R, Goldberg SR. Adenosine-cannabinoid receptor interactions. Implications for striatal function. British Journal of Pharmacology. 160: 443-53. PMID 20590556 DOI: 10.1111/j.1476-5381.2010.00723.x |
0.599 |
|
| 2010 |
Navarro G, Ferré S, Cordomi A, Moreno E, Mallol J, Casadó V, Cortés A, Hoffmann H, Ortiz J, Canela EI, LluÃs C, Pardo L, Franco R, Woods AS. Interactions between intracellular domains as key determinants of the quaternary structure and function of receptor heteromers. The Journal of Biological Chemistry. 285: 27346-59. PMID 20562103 DOI: 10.1074/Jbc.M110.115634 |
0.641 |
|
| 2010 |
Casadó V, Barrondo S, Spasic M, Callado LF, Mallol J, Canela E, Lluís C, Meana J, Cortés A, Sallés J, Franco R. Gi protein coupling to adenosine A1-A2A receptor heteromers in human brain caudate nucleus. Journal of Neurochemistry. 114: 972-80. PMID 20477947 DOI: 10.1111/j.1471-4159.2010.06810.x |
0.628 |
|
| 2009 |
Soriano A, Vendrell M, Gonzalez S, Mallol J, Albericio F, Royo M, Lluís C, Canela EI, Franco R, Cortés A, Casadó V. A hybrid indoloquinolizidine peptide as allosteric modulator of dopamine D1 receptors. The Journal of Pharmacology and Experimental Therapeutics. 332: 876-85. PMID 20026675 DOI: 10.1124/Jpet.109.158824 |
0.437 |
|
| 2009 |
Canela L, Fernández-Dueñas V, Albergaria C, Watanabe M, Lluís C, Mallol J, Canela EI, Franco R, Luján R, Ciruela F. The association of metabotropic glutamate receptor type 5 with the neuronal Ca2+-binding protein 2 modulates receptor function. Journal of Neurochemistry. 111: 555-67. PMID 19694902 DOI: 10.1111/J.1471-4159.2009.06348.X |
0.738 |
|
| 2009 |
Casadó V, Cortés A, Mallol J, Pérez-Capote K, Ferré S, Lluis C, Franco R, Canela EI. GPCR homomers and heteromers: a better choice as targets for drug development than GPCR monomers? Pharmacology & Therapeutics. 124: 248-57. PMID 19664655 DOI: 10.1016/j.pharmthera.2009.07.005 |
0.393 |
|
| 2009 |
Casadó V, Ferrada C, Bonaventura J, Gracia E, Mallol J, Canela EI, Lluís C, Cortés A, Franco R. Useful pharmacological parameters for G-protein-coupled receptor homodimers obtained from competition experiments. Agonist-antagonist binding modulation. Biochemical Pharmacology. 78: 1456-63. PMID 19643089 DOI: 10.1016/j.bcp.2009.07.012 |
0.601 |
|
| 2009 |
Navarro G, Aymerich MS, Marcellino D, Cortés A, Casadó V, Mallol J, Canela EI, Agnati L, Woods AS, Fuxe K, LluÃs C, Lanciego JL, Ferré S, Franco R. Interactions between calmodulin, adenosine A2A, and dopamine D2 receptors. The Journal of Biological Chemistry. 284: 28058-68. PMID 19632986 DOI: 10.1074/Jbc.M109.034231 |
0.552 |
|
| 2009 |
Vendrell M, Soriano A, Casadó V, Díaz JL, Lavilla R, Canela EI, Lluís C, Franco R, Albericio F, Royo M. Indoloquinolizidine-peptide hybrids as multiple agonists for D1 and D2 dopamine receptors. Chemmedchem. 4: 1514-22. PMID 19557804 DOI: 10.1002/Cmdc.200900149 |
0.445 |
|
| 2009 |
Ferrada C, Moreno E, Casadó V, Bongers G, Cortés A, Mallol J, Canela EI, Leurs R, Ferré S, Lluís C, Franco R. Marked changes in signal transduction upon heteromerization of dopamine D1 and histamine H3 receptors. British Journal of Pharmacology. 157: 64-75. PMID 19413572 DOI: 10.1111/J.1476-5381.2009.00152.X |
0.588 |
|
| 2008 |
Navarro G, Carriba P, Gandía J, Ciruela F, Casadó V, Cortés A, Mallol J, Canela EI, Lluis C, Franco R. Detection of heteromers formed by cannabinoid CB1, dopamine D2, and adenosine A2A G-protein-coupled receptors by combining bimolecular fluorescence complementation and bioluminescence energy transfer. Thescientificworldjournal. 8: 1088-97. PMID 18956124 DOI: 10.1100/Tsw.2008.136 |
0.674 |
|
| 2008 |
Gracia E, Cortés A, Meana JJ, García-Sevilla J, Herhsfield MS, Canela EI, Mallol J, Lluís C, Franco R, Casadó V. Human adenosine deaminase as an allosteric modulator of human A1 adenosine receptor: abolishment of negative cooperativity for [3H](R)‐pia binding to the caudate nucleus Journal of Neurochemistry. 107: 161-170. PMID 18680557 DOI: 10.1111/J.1471-4159.2008.05602.X |
0.526 |
|
| 2008 |
Franco R, Casadó V, Cortés A, Pérez-Capote K, Mallol J, Canela E, Ferré S, Lluis C. Novel pharmacological targets based on receptor heteromers. Brain Research Reviews. 58: 475-82. PMID 18620000 DOI: 10.1016/j.brainresrev.2008.06.002 |
0.631 |
|
| 2008 |
Carriba P, Navarro G, Ciruela F, Ferré S, Casadó V, Agnati L, Cortés A, Mallol J, Fuxe K, Canela EI, LluÃs C, Franco R. Detection of heteromerization of more than two proteins by sequential BRET-FRET. Nature Methods. 5: 727-33. PMID 18587404 DOI: 10.1038/Nmeth.1229 |
0.583 |
|
| 2008 |
Ferrada C, Ferré S, Casadó V, Cortés A, Justinova Z, Barnes C, Canela EI, Goldberg SR, Leurs R, Lluis C, Franco R. Interactions between histamine H3 and dopamine D2 receptors and the implications for striatal function. Neuropharmacology. 55: 190-7. PMID 18547596 DOI: 10.1016/J.Neuropharm.2008.05.008 |
0.569 |
|
| 2007 |
Franco R, Casadó V, Cortés A, Ferrada C, Mallol J, Woods A, Lluis C, Canela EI, Ferré S. Basic concepts in G-protein-coupled receptor homo- and heterodimerization. Thescientificworldjournal. 7: 48-57. PMID 17982576 DOI: 10.1100/Tsw.2007.197 |
0.62 |
|
| 2007 |
Casadó V, Cortés A, Ciruela F, Mallol J, Ferré S, Lluis C, Canela EI, Franco R. Old and new ways to calculate the affinity of agonists and antagonists interacting with G-protein-coupled monomeric and dimeric receptors: the receptor-dimer cooperativity index. Pharmacology & Therapeutics. 116: 343-54. PMID 17935788 DOI: 10.1016/J.Pharmthera.2007.05.010 |
0.732 |
|
| 2007 |
Canela L, Luján R, Lluís C, Burgueño J, Mallol J, Canela EI, Franco R, Ciruela F. The neuronal Ca(2+) -binding protein 2 (NECAB2) interacts with the adenosine A(2A) receptor and modulates the cell surface expression and function of the receptor. Molecular and Cellular Neurosciences. 36: 1-12. PMID 17689978 DOI: 10.1016/J.Mcn.2007.05.007 |
0.711 |
|
| 2007 |
Carriba P, Ortiz O, Patkar K, Justinova Z, Stroik J, Themann A, Müller C, Woods AS, Hope BT, Ciruela F, Casadó V, Canela EI, Lluis C, Goldberg SR, Moratalla R, et al. Striatal adenosine A2A and cannabinoid CB1 receptors form functional heteromeric complexes that mediate the motor effects of cannabinoids. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 2249-59. PMID 17356572 DOI: 10.1038/Sj.Npp.1301375 |
0.695 |
|
| 2007 |
Cabello N, Remelli R, Canela L, Soriguera A, Mallol J, Canela EI, Robbins MJ, Lluis C, Franco R, McIlhinney RA, Ciruela F. Actin-binding protein alpha-actinin-1 interacts with the metabotropic glutamate receptor type 5b and modulates the cell surface expression and function of the receptor. The Journal of Biological Chemistry. 282: 12143-53. PMID 17311919 DOI: 10.1074/Jbc.M608880200 |
0.739 |
|
| 2006 |
Franco R, Casadó V, Mallol J, Ferrada C, Ferré S, Fuxe K, Cortés A, Ciruela F, Lluis C, Canela EI. The two-state dimer receptor model: a general model for receptor dimers. Molecular Pharmacology. 69: 1905-12. PMID 16501032 DOI: 10.1124/Mol.105.020685 |
0.694 |
|
| 2006 |
Ciruela F, Casadó V, Rodrigues RJ, Luján R, Burgueño J, Canals M, Borycz J, Rebola N, Goldberg SR, Mallol J, Cortés A, Canela EI, López-Giménez JF, Milligan G, Lluis C, et al. Presynaptic control of striatal glutamatergic neurotransmission by adenosine A1-A2A receptor heteromers. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 2080-7. PMID 16481441 DOI: 10.1523/Jneurosci.3574-05.2006 |
0.684 |
|
| 2005 |
Ciruela F, Canela L, Burgueño J, Soriguera A, Cabello N, Canela EI, Casadó V, Cortés A, Mallol J, Woods AS, Ferré S, Lluis C, Franco R. Heptaspanning membrane receptors and cytoskeletal/scaffolding proteins: focus on adenosine, dopamine, and metabotropic glutamate receptor function. Journal of Molecular Neuroscience : Mn. 26: 277-92. PMID 16012201 DOI: 10.1385/Jmn:26:2-3:277 |
0.699 |
|
| 2005 |
Franco R, Ciruela F, Casadó V, Cortes A, Canela EI, Mallol J, Agnati LF, Ferré S, Fuxe K, Lluis C. Partners for adenosine A1 receptors. Journal of Molecular Neuroscience : Mn. 26: 221-32. PMID 16012195 DOI: 10.1385/Jmn:26:2-3:221 |
0.735 |
|
| 2005 |
Franco R, Casadó V, Mallol J, Ferré S, Fuxe K, Cortés A, Ciruela F, Lluis C, Canela EI. Dimer-based model for heptaspanning membrane receptors. Trends in Biochemical Sciences. 30: 360-6. PMID 15951182 DOI: 10.1016/J.Tibs.2005.05.010 |
0.666 |
|
| 2005 |
Canals M, Angulo E, Casadó V, Canela EI, Mallol J, Viñals F, Staines W, Tinner B, Hillion J, Agnati L, Fuxe K, Ferré S, Lluis C, Franco R. Molecular mechanisms involved in the adenosine A and A receptor-induced neuronal differentiation in neuroblastoma cells and striatal primary cultures. Journal of Neurochemistry. 92: 337-48. PMID 15663481 DOI: 10.1111/j.1471-4159.2004.02856.x |
0.454 |
|
| 2004 |
Burgueño J, Canela EI, Mallol J, Lluis C, Franco R, Ciruela F. Mutual regulation between metabotropic glutamate type 1alpha receptor and caveolin proteins: from traffick to constitutive activity. Experimental Cell Research. 300: 23-34. PMID 15383311 DOI: 10.1016/J.Yexcr.2004.06.013 |
0.74 |
|
| 2004 |
Agnati LF, Ferré S, Leo G, Lluis C, Canela EI, Franco R, Fuxe K. On the molecular basis of the receptor mosaic hypothesis of the engram. Cellular and Molecular Neurobiology. 24: 501-16. PMID 15233375 |
0.567 |
|
| 2004 |
Canals M, Burgueño J, Marcellino D, Cabello N, Canela EI, Mallol J, Agnati L, Ferré S, Bouvier M, Fuxe K, Ciruela F, Lluis C, Franco R. Homodimerization of adenosine A2A receptors: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer. Journal of Neurochemistry. 88: 726-34. PMID 14720222 DOI: 10.1046/J.1471-4159.2003.02200.X |
0.713 |
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| 2004 |
Angulo E, Casadó V, Mallol J, Canela EI, Viñals F, Ferrer I, Lluis C, Franco R. A1 adenosine receptors accumulate in neurodegenerative structures in Alzheimer disease and mediate both amyloid precursor protein processing and tau phosphorylation and translocation. Brain Pathology (Zurich, Switzerland). 13: 440-51. PMID 14655750 DOI: 10.1111/j.1750-3639.2003.tb00475.x |
0.487 |
|
| 2003 |
Burgueño J, Enrich C, Canela EI, Mallol J, Lluis C, Franco R, Ciruela F. Metabotropic glutamate type 1α receptor localizes in low-density caveolin-rich plasma membrane fractions Journal of Neurochemistry. 86: 785-791. PMID 12887677 DOI: 10.1046/J.1471-4159.2003.01842.X |
0.706 |
|
| 2003 |
Burgueño J, Blake DJ, Benson MA, Tinsley CL, Esapa CT, Canela EI, Penela P, Mallol J, Mayor F, Lluis C, Franco R, Ciruela F. The adenosine A2A receptor interacts with the actin-binding protein alpha-actinin. The Journal of Biological Chemistry. 278: 37545-52. PMID 12837758 DOI: 10.1074/Jbc.M302809200 |
0.717 |
|
| 2003 |
Franco R, Canals M, Marcellino D, Ferré S, Agnati L, Mallol J, Casadó V, Ciruela F, Fuxe K, Lluis C, Canela EI. Regulation of heptaspanning-membrane-receptor function by dimerization and clustering. Trends in Biochemical Sciences. 28: 238-43. PMID 12765835 DOI: 10.1016/S0968-0004(03)00065-3 |
0.728 |
|
| 2003 |
Escriche M, Burgueño J, Ciruela F, Canela EI, Mallol J, Enrich C, Lluís C, Franco R. Ligand-induced caveolae-mediated internalization of A1 adenosine receptors: Morphological evidence of endosomal sorting and receptor recycling Experimental Cell Research. 285: 72-90. PMID 12681288 DOI: 10.1016/S0014-4827(02)00090-3 |
0.707 |
|
| 2002 |
Hillion J, Canals M, Torvinen M, Casado V, Scott R, Terasmaa A, Hansson A, Watson S, Olah ME, Mallol J, Canela EI, Zoli M, Agnati LF, Ibanez CF, Lluis C, et al. Coaggregation, cointernalization, and codesensitization of adenosine A2A receptors and dopamine D2 receptors. The Journal of Biological Chemistry. 277: 18091-7. PMID 11872740 DOI: 10.1074/jbc.M107731200 |
0.589 |
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