Manfred Jung
Affiliations: | Albert-Ludwigs-University Freiburg, Freiburg im Breisgau, Baden-Württemberg, Germany |
Area:
Medicinal Chemistry, Chemical EpigeneticsWebsite:
http://www.pharmazie.uni-freiburg.de/chemie/german/professoren/akjunghp/Google:
"Manfred Jung"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Wolfgang Hanefeld | grad student | University of Marburg | |
| Tony Durst | post-doc |
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Publications
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| Wang S, Barthes NPF, Urban S, et al. (2025) Structure-Guided Design of a KMT9 Inhibitor Prodrug with Cellular Activity. Journal of Medicinal Chemistry |
| Baumann A, Papenkordt N, Robaa D, et al. (2024) Aromatic Amino Acid Hydroxylases as Off-Targets of Histone Deacetylase Inhibitors. Acs Chemical Neuroscience. 15: 4143-4155 |
| Seitz J, Auth M, Prinz T, et al. (2024) Soft drug inhibitors for the epigenetic targets lysine-specific demethylase 1 and histone deacetylases. Archiv Der Pharmazie. e2400450 |
| Colcerasa A, Friedrich F, Melesina J, et al. (2024) Structure-Activity Studies of 1,2,4-Oxadiazoles for the Inhibition of the NAD-Dependent Lysine Deacylase Sirtuin 2. Journal of Medicinal Chemistry |
| Wang S, Klein SO, Urban S, et al. (2024) Structure-guided design of a selective inhibitor of the methyltransferase KMT9 with cellular activity. Nature Communications. 15: 43 |
| Abdelsalam M, Zmyslia M, Schmidtkunz K, et al. (2023) Design and synthesis of bioreductive prodrugs of class I histone deacetylase inhibitors and their biological evaluation in virally transfected acute myeloid leukemia cells. Archiv Der Pharmazie. e2300536 |
| Sinatra L, Vogelmann A, Friedrich F, et al. (2023) Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin Deacetylation. Journal of Medicinal Chemistry. 66: 14787-14814 |
| Helmi YY, Papenkordt N, Rennar G, et al. (2023) Melatonin-vorinostat hybrid ligands show higher histone deacetylase and cancer cell growth inhibition than vorinostat. Archiv Der Pharmazie. e2300149 |
| Kohr M, Papenkordt N, Jung M, et al. (2023) Total synthesis and biological evaluation of histone deacetylase inhibitor WF-3161. Organic & Biomolecular Chemistry |
| Darwish S, Heimburg T, Ridinger J, et al. (2022) Synthesis, Biochemical, and Cellular Evaluation of HDAC6 Targeting Proteolysis Targeting Chimeras. Methods in Molecular Biology (Clifton, N.J.). 2589: 179-193 |