Raylene J. Sanchez, Ph.D.

Affiliations: 
2003 University of California, Los Angeles, Los Angeles, CA 
Area:
Copper-Zinc Superoxide Dismutase and ALS, Redox Balance, Oxidative Stress, and Metal Ion Metabolism in Eukaryotic Cells
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"Raylene Sanchez"
Mean distance: 8.81
 
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Joan Selverstone Valentine grad student 2003 UCLA
 (Investigation of the beneficial and toxic roles of transition metals in yeast lacking copper-zinc superoxide dismutase.)
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Publications

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Sanchez RJ, Srinivasan C, Munroe WH, et al. (2005) Exogenous manganous ion at millimolar levels rescues all known dioxygen-sensitive phenotypes of yeast lacking CuZnSOD. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 10: 913-23
Jensen LT, Sanchez RJ, Srinivasan C, et al. (2004) Mutations in Saccharomyces cerevisiae iron-sulfur cluster assembly genes and oxidative stress relevant to Cu,Zn superoxide dismutase. The Journal of Biological Chemistry. 279: 29938-43
Zhu H, Shipp E, Sanchez RJ, et al. (2000) Cobalt(2+) binding to human and tomato copper chaperone for superoxide dismutase: implications for the metal ion transfer mechanism. Biochemistry. 39: 5413-21
Hall LT, Sanchez RJ, Holloway SP, et al. (2000) X-ray crystallographic and analytical ultracentrifugation analyses of truncated and full-length yeast copper chaperones for SOD (LYS7): a dimer-dimer model of LYS7-SOD association and copper delivery. Biochemistry. 39: 3611-23
Goto JJ, Zhu H, Sanchez RJ, et al. (2000) Loss of in vitro metal ion binding specificity in mutant copper-zinc superoxide dismutases associated with familial amyotrophic lateral sclerosis. The Journal of Biological Chemistry. 275: 1007-14
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