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Albert Dorfman, Ph.D., M.D.

Affiliations: 
University of Chicago, Chicago, IL 
Area:
Polysaccharides
Website:
http://www.nap.edu/readingroom.php?book=biomems&page=adorfman.html
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"Albert Dorfman"
Bio:

(1916 - 1982)
http://www.nasonline.org/member-directory/deceased-members/56247.html
ALBERT DORFMAN's research for more than thirty-five years on the biosynthesis and chemistry of bacterial and connective tissue polysaccharides provided the basis for many medical advances in human biochemical genetics, as well as in prenatal diagnosis of genetic diseases that cause mental retardation. One of his many scientific accomplishments was discovering the cause of Hurler's syndrome, a genetic disease that affects the bones and cartilage and results in mental retardation.

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Parents

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Felix Wadsworth Saunders grad student 1939 Chicago
 (Studies on the essential growth requirements of the dysentery bacillus)

Children

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Robert L. Perlman grad student 1963 Chicago
Saul Roseman post-doc 1953 Chicago

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Publications

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Dorfman A, Lorincz AE. (2006) OCCURRENCE OF URINARY ACID MUCOPOLYSACCHARIDES IN THE HURLER SYNDROME. Proceedings of the National Academy of Sciences of the United States of America. 43: 443-6
KULONEN E, MATHEWS MB, DORFMAN A. (2003) Studies in procollagen. I. Solubility. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 84: 424-8
SCHILLER S, SLOVER GA, DORFMAN A. (1998) Effect of the thyroid gland on metabolism of acid mucopolysaccharides in skin. Biochimica Et Biophysica Acta. 58: 27-33
SIREK OV, SCHILLER S, DORFMAN A. (1996) ACID MUCOPOLYSACCHARIDES IN AORTIC TISSUE OF THE DOG. Biochimica Et Biophysica Acta. 83: 148-51
Horwitz AL, Hancock L, Dawson G, et al. (1981) 727 GENERALIZED SIALIC ACID STORAGE DISEASE Pediatric Research. 15: 563-563
Underhill C, Dorfman A. (1978) The role of hyaluronic acid in intercellular adhesion of cultured mouse cells Experimental Cell Research. 117: 155-164
Hopwood JJ, Dorfman A. (1978) Glycosaminoglycan synthesis by wilms’ tumor Pediatric Research. 12: 52-56
Morris JE, Hopwood JJ, Dorfman A. (1977) Biosynthesis of glycosaminoglycans in the developing retina. Developmental Biology. 58: 313-27
Ho PL, Levitt D, Dorfman A. (1977) A radioimmune study of the effect of bromodeoxyuridine on the synthesis of proteoglycan by differentiating limb bud cultures Developmental Biology. 55: 233-243
Morris JE, Dorfman A. (1976) Inhibition by 5-bromo-2′-deoxyuridine of differentiation-dependent changes in glycosaminoglycans of the retina Biochemical and Biophysical Research Communications. 69: 1065-1072
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