Joshua J. Rychak, Ph.D.

2005 University of Virginia, Charlottesville, VA 
Biomedical Engineering
"Joshua Rychak"


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Klaus Ley grad student 2005 UVA
 (Lessons from leukocytes: Engineering efficient retention of targeted ultrasound contrast agents for molecular imaging.)
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Luong A, Smith D, Tai CH, et al. (2019) Development of a Translatable Ultrasound Molecular Imaging Agent for Inflammation. Ultrasound in Medicine & Biology
Alvarez E, Dalton ND, Gu Y, et al. (2017) A Novel Method for Quantitative Myocardial Contrast Echocardiography in Mice. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00568.2017
Wei S, Xu C, Rychak JJ, et al. (2016) Short Hairpin RNA Knockdown of Connective Tissue Growth Factor by Ultrasound-Targeted Microbubble Destruction Improves Renal Fibrosis. Ultrasound in Medicine & Biology
Shekhar H, Awuor I, Thomas K, et al. (2014) The delayed onset of subharmonic and ultraharmonic emissions from a phospholipid-shelled microbubble contrast agent. Ultrasound in Medicine & Biology. 40: 727-38
Kilroy JP, Patil AV, Rychak JJ, et al. (2014) An IVUS transducer for microbubble therapies. Ieee Transactions On Ultrasonics, Ferroelectrics, and Frequency Control. 61: 441-9
Rychak JJ, Klibanov AL. (2014) Nucleic acid delivery with microbubbles and ultrasound. Advanced Drug Delivery Reviews. 72: 82-93
Tlaxca JL, Rychak JJ, Ernst PB, et al. (2014) Corrigendum to “Ultrasound-based molecular imaging and specific gene delivery to mesenteric vasculature by endothelial adhesion molecule targeted microbubbles in a mouse model of Crohn's disease” [J. Control. Release 165 (2013) 216–225] Journal of Controlled Release. 173: 10
Declèves AE, Rychak JJ, Smith DJ, et al. (2013) Effects of high-fat diet and losartan on renal cortical blood flow using contrast ultrasound imaging. American Journal of Physiology. Renal Physiology. 305: F1343-51
Shekhar H, Rychak JJ, Doyley MM. (2013) Modifying the size distribution of microbubble contrast agents for high-frequency subharmonic imaging. Medical Physics. 40: 082903
Hu X, Caskey CF, Mahakian LM, et al. (2013) In vivo validation and 3D visualization of broadband ultrasound molecular imaging. American Journal of Nuclear Medicine and Molecular Imaging. 3: 336-49
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