Sergio Iadevaia, Ph.D.

Affiliations: 
2008 Rice University, Houston, TX 
Area:
Chemical Engineering
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"Sergio Iadevaia"

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Kyriacos Zygourakis grad student 2008 Rice University (E-Tree)
 (Design of artificial genetic networks to regulate the biosynthesis of polyhydroxyalkanoate copolymers with desirable structures.)
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Publications

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Camblin AJ, Tan G, Curley MD, et al. (2019) Dual targeting of IGF-1R and ErbB3 as a potential therapeutic regimen for ovarian cancer. Scientific Reports. 9: 16832
Camblin AJ, Pace EA, Adams S, et al. (2018) Dual inhibition of IGF-1R and ErbB3 enhances the activity of gemcitabine and nab-paclitaxel in preclinical models of pancreatic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research
Curley MD, Tan G, Yannatos I, et al. (2016) Abstract 1209: Istiratumab (MM-141), a bispecific antibody targeting IGF-1R and ErbB3, inhibits pro-survival signaling in vitro and potentiates the activity of standard of care chemotherapy in vivo in ovarian cancer models Cancer Research. 76: 1209-1209
Pace E, Adams S, Camblin A, et al. (2015) Effect of MM-141 on gemcitabine and nab-paclitaxel potentiation in preclinical models of pancreatic cancer through induction of IGF-1R and ErbB3 degradation. Journal of Clinical Oncology. 33: 289-289
Masson K, Grantcharova V, Burenkova O, et al. (2015) Abstract LB-243: The ErbB3-targeting antibody MM-121 (seribantumab) reverses heregulin-driven resistance to multiple chemotherapies on tumor cell growth Cancer Research. 75
Lugovskoy AA, Curley M, Baum J, et al. (2015) Abstract CT237: Preclinical characterization and first-in-human study of MM-141, a dual antibody inhibitor of IGF-1R and ErbB3 Cancer Research. 75
Adams S, Curley MD, Camblin AJ, et al. (2015) Abstract A89: Istiratumab (MM-141), a bispecific antibody co-targeting IGF-1R and ErbB3, potentiates the activity of immune checkpoint inhibitors Molecular Cancer Therapeutics. 14
Iadevaia S, Nakhleh LK, Azencott R, et al. (2014) Mapping network motif tunability and robustness in the design of synthetic signaling circuits. Plos One. 9: e91743
Fitzgerald JB, Johnson BW, Baum J, et al. (2014) MM-141, an IGF-IR- and ErbB3-directed bispecific antibody, overcomes network adaptations that limit activity of IGF-IR inhibitors. Molecular Cancer Therapeutics. 13: 410-25
Adams S, Baum J, Sparta B, et al. (2013) Abstract C169: MM-141, a bispecific antibody inhibitor of PI3K/AKT/mTOR, attenuates tumor growth and potentiates everolimus in mouse models of anti-hormonal therapy-resistant ER/PR+ breast cancer. Molecular Cancer Therapeutics. 12
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