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Thomas A. Steitz

Affiliations: 
Molecular Biophysics and Biochemistry Yale University, New Haven, CT 
Area:
Biochemistry, structural chemistry
Website:
https://www.nobelprize.org/prizes/chemistry/2009/steitz/biographical/
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"Thomas A. Steitz"
Bio:

(1940 - 2018)
http://www.nasonline.org/member-directory/deceased-members/8586.html
https://history.aip.org/phn/11811001.html
http://medicine.yale.edu/mbb/faculty/thomas_steitz.profile
http://www.chem.yale.edu/faculty/steitz.html
http://www.yale.edu/steitz/
The Nobel Prize in Chemistry 2009 was awarded jointly to Venkatraman Ramakrishnan, Thomas A. Steitz and Ada E. Yonath "for studies of the structure and function of the ribosome".

Mean distance: 7.13
 		SNBCP
Cross-listing: Crystallography Tree - StructuralBiologyTree

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Parents

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Laszlo Lorand research assistant 1960-1960 Northwestern
 (Kinetic study of the hydrolysis of a variety of para-nitrophenyl ester substrate analogues by chymotrypsin, trypsin and thrombin.)
William N. Lipscomb grad student 1966 Harvard
David M. Blow post-doc 1967-1970 MRC-LMB

Children

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John J. Perona grad student Yale
Timothy J. Richmond grad student 1975 Yale
Adrian Goldman grad student 1980-1985 Yale
Phoebe A. Rice grad student 1992 Yale
David Jeruzalmi grad student 1994 Yale
Chad A. Brautigam grad student 1997 Yale
Daniel L. Kaplan grad student 2000 Yale
Andres E. Leschziner grad student 2000 Yale
Matthew C. Franklin grad student 2001 Yale
Huiming Li grad student 2001 Yale
Min Lu grad student 2001 Yale
Kakoli Mitra grad student 2001 Yale
Fang Li grad student 2002 Yale
Bo-Lu Zhou grad student 2002 Yale
Daniel Joseph Klein grad student 2004 Yale
Weikai Li grad student 2004 Yale
T. Martin Schmeing grad student 2004 Yale
Daqi Tu grad student 2005 Yale
Jennifer M. Kavran grad student 2006 Yale
Andrea J. Berman grad student 2001-2007 Yale
Kimberly J. Durniak grad student 2008 Yale
Hitesh Sharma grad student 2009 Yale
Robin E. Stanley grad student 2009 Yale
Richard A. Wing grad student 2010 Yale
David Bulkley grad student 2013 Yale
Raktim N Roy grad student 2014-2019 Yale
Robert J. Fletterick post-doc Yale
Wekai Li post-doc Yale
Steve C. Schultz post-doc Yale
Bin Liu post-doc 2008- Yale
David Bruce McKay post-doc 1978-1982 Yale
Lorena S. Beese post-doc 1986-1992 Yale
Wei Yang post-doc 1992-1995 Yale
Soo Hyun Eom post-doc 1994-1997 Yale
Jeffrey Lewis Hansen post-doc 2003 Yale (Evolution Tree)

Collaborators

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Publications

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Zuo Y, De S, Feng Y, et al. (2020) Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience. 23: 101445
Lomakin IB, De S, Wang J, et al. (2020) Crystal structure of the C-terminal domain of DENR. Computational and Structural Biotechnology Journal. 18: 696-704
Joseph NN, Roy RN, Steitz TA. (2020) Molecular dynamics analysis of Mg -dependent cleavage of a pistol ribozyme reveals a fail-safe secondary ion for catalysis. Journal of Computational Chemistry
Lomakin IB, Dmitriev SE, Steitz TA. (2018) Crystal structure of the DENR-MCT-1 complex revealed zinc-binding site essential for heterodimer formation. Proceedings of the National Academy of Sciences of the United States of America
Lin J, Zhou D, Steitz TA, et al. (2018) Ribosome-Targeting Antibiotics: Modes of Action, Mechanisms of Resistance, and Implications for Drug Design. Annual Review of Biochemistry
Liu B, Hong C, Huang RK, et al. (2017) Structural basis of bacterial transcription activation. Science (New York, N.Y.). 358: 947-951
Vaidya AT, Lomakin IB, Joseph NN, et al. (2017) Crystal Structure of the C-terminal Domain of Human eIF2D and its Implications on Eukaryotic Translation Initiation. Journal of Molecular Biology
Lomakin IB, Stolboushkina EA, Vaidya AT, et al. (2017) Crystal Structure of the Human Ribosome in Complex with DENR-MCT-1. Cell Reports. 20: 521-528
Nguyen LA, Wang J, Steitz TA. (2017) Crystal structure of Pistol, a class of self-cleaving ribozyme. Proceedings of the National Academy of Sciences of the United States of America
Liu B, Steitz TA. (2016) Structural insights into NusG regulating transcription elongation. Nucleic Acids Research
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