James E. Bear, Ph.D.
Affiliations: | Cell and Developmental Biology | University of North Carolina, Chapel Hill, Chapel Hill, NC |
Area:
cell migrationWebsite:
http://www.med.unc.edu/cellbiophysio/faculty/bearGoogle:
"james bear"Parents
Sign in to add mentor| Charles Saxe | grad student | 1993-1998 | Emory |
| Frank B. Gertler | post-doc | 2002 | MIT (Neurotree) |
Children
Sign in to add trainee| Liang Cai | grad student | 2003-2007 | UNC Chapel Hill |
| Thomas W. Marshall | grad student | 2009 | UNC Chapel Hill |
| Andrea C. Uetrecht | grad student | 2009 | UNC Chapel Hill |
| Congying Wu | grad student | 2013 | UNC Chapel Hill |
| Elizabeth M Haynes | grad student | 2011-2015 | UNC Chapel Hill (danioTree) |
BETA: Related publications
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Publications
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| Cisterna BA, Skruber K, Jane ML, et al. (2024) Prolonged depletion of profilin 1 or F-actin causes an adaptive response in microtubules. The Journal of Cell Biology. 223 |
| Quintanilla MA, Patel H, Wu H, et al. (2024) Local monomer levels and established filaments potentiate non-muscle myosin 2 assembly. The Journal of Cell Biology. 223 |
| Appalabhotla R, Butler MT, Bear JE, et al. (2023) G-actin diffusion is insufficient to achieve F-actin assembly in fast-treadmilling protrusions. Biophysical Journal |
| Quintanilla MA, Patel H, Wu H, et al. (2023) Local Monomer Levels and Established Filaments Potentiate Non-Muscle Myosin 2 Assembly. Biorxiv : the Preprint Server For Biology |
| Hakeem RM, Subramanian BC, Hockenberry MA, et al. (2022) A Photopolymerized Hydrogel System with Dual Stiffness Gradients Reveals Distinct Actomyosin-Based Mechano-Responses in Fibroblast Durotaxis. Acs Nano |
| King ZT, Butler MT, Hockenberry MA, et al. (2022) Coro1B and Coro1C regulate lamellipodia dynamics and cell motility by tuning branched actin turnover. The Journal of Cell Biology. 221 |
| Chandra A, Butler MT, Bear JE, et al. (2022) Modeling cell protrusion predicts how myosin II and actin turnover affect adhesion-based signaling. Biophysical Journal. 121: 102-118 |
| Eckly A, Scandola C, Oprescu A, et al. (2020) Megakaryocytes use in vivo podosome-like structures working collectively to penetrate the endothelial barrier of bone marrow sinusoids. Journal of Thrombosis and Haemostasis : Jth |
| Tagliatela AC, Hempstead SC, Hibshman PS, et al. (2020) Coronin 1C inhibits melanoma metastasis through regulation of MT1-MMP-containing extracellular vesicle secretion. Scientific Reports. 10: 11958 |
| Nosbisch JL, Rahman A, Mohan K, et al. (2020) Mechanistic models of PLC/PKC signaling implicate phosphatidic acid as a key amplifier of chemotactic gradient sensing. Plos Computational Biology. 16: e1007708 |