Michael C Wendl, PhD
Affiliations: | 1994- | Genetics (McDonnell Genome Institute) | Washington University, Saint Louis, St. Louis, MO |
| 1999- | Mechanical Engineering | Washington University, Saint Louis, St. Louis, MO | |
| 2010- | Mathematics | Washington University, Saint Louis, St. Louis, MO |
Area:
differential equations, combinatorial probability, fluid mechanics, statistical geneticsWebsite:
wendl.weebly.comGoogle:
"Michael Wendl"Cross-listing: Physics Tree - E-Tree - GenetiTree
Parents
Sign in to add mentor| Ramesh Agarwal | grad student | 1990-1994 | (E-Tree) |
| Robert Waterston | post-doc | 1994-2001 | (GenetiTree) |
Collaborators
Sign in to add collaborator| Nathan D. Dees | collaborator | Washington University (Neurotree) | |
| Li Ding | collaborator | Washington University (Neurotree) | |
| David Larson | collaborator | Washington University (FlyTree) | |
| Adam D. Scott | collaborator | Washington University (Neurotree) |
BETA: Related publications
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Publications
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| Wu Y, Chen S, Yang X, et al. (2023) Combining the Tyrosine Kinase Inhibitor Cabozantinib and the mTORC1/2 Inhibitor Sapanisertib Blocks ERK Pathway Activity and Suppresses Tumor Growth in Renal Cell Carcinoma. Cancer Research. 83: 4161-4178 |
| Iglesia MD, Jayasinghe RG, Chen S, et al. (2023) Differential chromatin accessibility and transcriptional dynamics define breast cancer subtypes and their lineages. Biorxiv : the Preprint Server For Biology |
| Terekhanova NV, Karpova A, Liang WW, et al. (2023) Epigenetic regulation during cancer transitions across 11 tumour types. Nature |
| Liang WW, Lu RJ, Jayasinghe RG, et al. (2023) Integrative multi-omic cancer profiling reveals DNA methylation patterns associated with therapeutic vulnerability and cell-of-origin. Cancer Cell |
| Li Y, Porta-Pardo E, Tokheim C, et al. (2023) Pan-cancer proteogenomics connects oncogenic drivers to functional states. Cell |
| Wu Y, Terekhanova NV, Caravan W, et al. (2023) Epigenetic and transcriptomic characterization reveals progression markers and essential pathways in clear cell renal cell carcinoma. Nature Communications. 14: 1681 |
| Yao L, Wang JT, Jayasinghe RG, et al. (2023) Single-cell discovery and multi-omic characterization of therapeutic targets in multiple myeloma. Cancer Research |
| Yao L, Jayasinghe RG, Lee BH, et al. (2022) Comprehensive Characterization of the Multiple Myeloma Immune Microenvironment Using Integrated scRNA-seq, CyTOF, and CITE-seq Analysis. Cancer Research Communications. 2: 1255-1265 |
| Li Y, Lih TM, Dhanasekaran SM, et al. (2022) Histopathologic and proteogenomic heterogeneity reveals features of clear cell renal cell carcinoma aggressiveness. Cancer Cell |
| Cui Zhou D, Jayasinghe RG, Chen S, et al. (2022) Spatially restricted drivers and transitional cell populations cooperate with the microenvironment in untreated and chemo-resistant pancreatic cancer. Nature Genetics |