Charles Heidelberger
Affiliations: | Southern California Comprehensive Cancer Center | University of Southern California, Los Angeles, CA, United States |
Area:
5-fluorouracil, fluorinated pyrimidinesWebsite:
http://www.nasonline.org/member-directory/deceased-members/54708.htmlGoogle:
"Charles Heidelberger"Bio:
(1920 - 1983)
https://www.nap.edu/read/1645/chapter/11
http://resource.nlm.nih.gov/101418238
Mean distance: 7.52 | S | N | B | C | P |
Parents
Sign in to add mentor| Louis Frederick Fieser | grad student | 1946 | Harvard | |
| (I. Some derivatives of p,p'-diaminodiphenyl sulfone. II. The synthesis and antimalarial activity of some naphthoquinones. III. A preliminary study of the mechanism of the peroxide alkylation of quinones.) | ||||
| Melvin Calvin | post-doc | 1946-1948 | UC Berkeley | |
Children
Sign in to add trainee| John William Keller | grad student | 1971-1976 | UW Madison |
| George Wolf | post-doc | 1950-1951 | UW Madison |
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Publications
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| HEIDELBERGER C, BOOHAR J, BIRNIE GD. (1996) FLUORINATED PYRIMIDINES. XXII. EFFECTS OF VARIOUS COMPOUNDS ON THE INCORPORATION OF (14C)FORMATE INTO DNA THYMINE IN SUSPENSIONS OF EHRLICH ASCITES CELLS. Biochimica Et Biophysica Acta. 91: 636-8 |
| Billings PC, Heidelberger C, Landolph JR. (1985) S-9 metabolic activation enhances aflatoxin-mediated transformation of C3H/10T1/2 cells. Toxicology and Applied Pharmacology. 77: 58-65 |
| Heidelberger C, Freeman AE, Pienta RJ, et al. (1983) Cell transformation by chemical agents--a review and analysis of the literature. A report of the U.S. Environmental Protection Agency Gene-Tox Program. Mutation Research. 114: 283-385 |
| Danenberg PV, Heidelberger C, Mulkins MA, et al. (1981) The incorporation of 5-fluoro-2'-deoxyuridine into DNA of mammalian tumor cells. Biochemical and Biophysical Research Communications. 102: 654-8 |
| Bhatt RS, Kundu NG, Chwang TL, et al. (1981) Synthesis of 5-ethynylorotic acid (Ia) Journal of Heterocyclic Chemistry. 18: 771-774 |
| Peterson AR, Fisher MS, Heidelberger C. (1980) Association between the cytotoxicity of thymidine and tumorigenicity of clones derived from C3H/10T1/2 mouse embryo fibroblasts. Biochemical and Biophysical Research Communications. 95: 182-6 |
| Fernandez A, Mondal S, Heidelberger C. (1980) Probabilistic view of the transformation of cultured C3H/10T1/2 mouse embryo fibroblasts by 3-methylcholanthrene. Proceedings of the National Academy of Sciences of the United States of America. 77: 7272-6 |
| Woodman PW, Sarrif AM, Heidelberger C. (1980) Inhibition of nucleoside phosphorylase cleavage of 5-fluoro-2'-deoxyuridine by 2,4-pyrimidinedione derivatives. Biochemical Pharmacology. 29: 1059-63 |
| Hannon SJ, Kundu NG, Hertzberg RP, et al. (1980) A new synthesis of n-blocked dihydrouracil and dihydroorotic acid derivatives using lithium tri-sec-butyl borohydride as reducing agent Tetrahedron Letters. 21: 1105-1108 |
| Heidelberger C, Gehly EB, Fahl WE, et al. (1980) Metabolism Of Benzo(A)Pyrene And Oncogenic Transformation Of C3H/10T1/2 Mouse Embryo Fibroblasts Microsomes, Drug Oxidations and Chemical Carcinogenesis. 1013-1024 |