Year |
Citation |
Score |
2020 |
Singh A, Kazer SW, Roider J, Krista KC, Millar J, Asowata OE, Ngoepe A, Ramsuran D, Fardoos R, Ardain A, Muenchhoff M, Kuhn W, Karim F, Ndung'u T, Shalek AK, et al. Innate Lymphoid Cell Activation and Sustained Depletion in Blood and Tissue of Children Infected with HIV from Birth Despite Antiretroviral Therapy. Cell Reports. 32: 108153. PMID 32937142 DOI: 10.1016/J.Celrep.2020.108153 |
0.303 |
|
2020 |
Sangesland M, Yousif AS, Ronsard L, Kazer SW, Zhu AL, Gatter GJ, Hayward MR, Barnes RM, Quirindongo-Crespo M, Rohrer D, Lonberg N, Kwon D, Shalek AK, Lingwood D. A Single Human V-gene Allows for a Broad-Spectrum Antibody Response Targeting Bacterial Lipopolysaccharides in the Blood. Cell Reports. 32: 108065. PMID 32846123 DOI: 10.1016/J.Celrep.2020.108065 |
0.31 |
|
2020 |
Mitsialis V, Wall S, Liu P, Ordovas-Montanes J, Parmet T, Vukovic M, Spencer D, Field M, McCourt C, Toothaker J, Bousvaros A, Shalek AK, Kean L, et al. Single-Cell Analyses of Colon and Blood Reveal Distinct Immune Cell Signatures of Ulcerative Colitis and Crohn's Disease. Gastroenterology. PMID 32428507 DOI: 10.1053/J.Gastro.2020.04.074 |
0.374 |
|
2020 |
Ziegler CGK, Allon SJ, Nyquist SK, Mbano IM, Miao VN, Tzouanas CN, Cao Y, Yousif AS, Bals J, Hauser BM, Feldman J, Muus C, Wadsworth MH, Kazer SW, Hughes TK, ... ... Shalek AK, et al. SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues. Cell. PMID 32413319 DOI: 10.1016/J.Cell.2020.04.035 |
0.433 |
|
2020 |
Gawel DR, Serra-Musach J, Lilja S, Aagesen J, Arenas A, Asking B, Bengnér M, Björkander J, Biggs S, Ernerudh J, Hjortswang H, Karlsson JE, Köpsen M, Lee EJ, Lentini A, ... ... Shalek AK, et al. Correction to: A validated single-cell-based strategy to identify diagnostic and therapeutic targets in complex diseases. Genome Medicine. 12: 37. PMID 32345376 DOI: 10.1186/S13073-020-00732-7 |
0.34 |
|
2020 |
Ding J, Adiconis X, Simmons SK, Kowalczyk MS, Hession CC, Marjanovic ND, Hughes TK, Wadsworth MH, Burks T, Nguyen LT, Kwon JYH, Barak B, Ge W, Kedaigle AJ, Carroll S, ... ... Shalek AK, et al. Author Correction: Systematic comparison of single-cell and single-nucleus RNA-sequencing methods. Nature Biotechnology. PMID 32341567 DOI: 10.1038/S41587-020-0534-Z |
0.353 |
|
2020 |
Ding J, Adiconis X, Simmons SK, Kowalczyk MS, Hession CC, Marjanovic ND, Hughes TK, Wadsworth MH, Burks T, Nguyen LT, Kwon JYH, Barak B, Ge W, Kedaigle AJ, Carroll S, ... ... Shalek AK, et al. Systematic comparison of single-cell and single-nucleus RNA-sequencing methods. Nature Biotechnology. PMID 32341560 DOI: 10.1038/S41587-020-0465-8 |
0.403 |
|
2020 |
Rozenblatt-Rosen O, Regev A, Oberdoerffer P, Nawy T, Hupalowska A, Rood JE, Ashenberg O, Cerami E, Coffey RJ, Demir E, Ding L, Esplin ED, Ford JM, Goecks J, Ghosh S, ... ... Shalek AK, et al. The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution. Cell. 181: 236-249. PMID 32302568 DOI: 10.1016/J.Cell.2020.03.053 |
0.355 |
|
2020 |
Kazer SW, Aicher TP, Muema DM, Carroll SL, Ordovas-Montanes J, Miao VN, Tu AA, Ziegler CGK, Nyquist SK, Wong EB, Ismail N, Dong M, Moodley A, Berger B, Love JC, ... ... Shalek AK, et al. Integrated single-cell analysis of multicellular immune dynamics during hyperacute HIV-1 infection. Nature Medicine. PMID 32251406 DOI: 10.1038/S41591-020-0799-2 |
0.481 |
|
2020 |
Ordovas-Montanes J, Beyaz S, Rakoff-Nahoum S, Shalek AK. Distribution and storage of inflammatory memory in barrier tissues. Nature Reviews. Immunology. PMID 32015472 DOI: 10.1038/S41577-019-0263-Z |
0.331 |
|
2020 |
Martin-Gayo E, Gao C, Chen HR, Ouyang Z, Kim D, Kolb KE, Shalek AK, Walker BD, Lichterfeld M, Yu XG. Immunological Fingerprints of Controllers Developing Neutralizing HIV-1 Antibodies. Cell Reports. 30: 984-996.e4. PMID 31995767 DOI: 10.1016/J.Celrep.2019.12.087 |
0.348 |
|
2020 |
Waldman BS, Schwarz D, Wadsworth MH, Saeij JP, Shalek AK, Lourido S. Identification of a Master Regulator of Differentiation in Toxoplasma. Cell. 180: 359-372.e16. PMID 31955846 DOI: 10.1016/J.Cell.2019.12.013 |
0.348 |
|
2020 |
Winter PS, Raghavan S, Navia AW, Williams H, Galvez-Reyes J, Kalekar R, Borah A, DenAdel A, Raghavan M, Lowder K, Mulugeta N, Wang J, Reilly E, Brais L, Crawford L, ... ... Shalek AK, et al. Abstract PR02: Matched metastatic pancreatic ductal adenocarcinoma biopsies and organoid models reveal tumor cell transcriptional plasticity and subtype-specific microenvironmental crosstalk Cancer Research. 80. DOI: 10.1158/1538-7445.Camodels2020-Pr02 |
0.42 |
|
2019 |
Tu AA, Gierahn TM, Monian B, Morgan DM, Mehta NK, Ruiter B, Shreffler WG, Shalek AK, Love JC. TCR sequencing paired with massively parallel 3' RNA-seq reveals clonotypic T cell signatures. Nature Immunology. 20: 1692-1699. PMID 31745340 DOI: 10.1038/S41590-019-0544-5 |
0.448 |
|
2019 |
Menon M, Mohammadi S, Davila-Velderrain J, Goods BA, Cadwell TD, Xing Y, Stemmer-Rachamimov A, Shalek AK, Love JC, Kellis M, Hafler BP. Single-cell transcriptomic atlas of the human retina identifies cell types associated with age-related macular degeneration. Nature Communications. 10: 4902. PMID 31653841 DOI: 10.1038/S41467-019-12780-8 |
0.41 |
|
2019 |
Farmer JR, Allard-Chamard H, Sun N, Ahmad M, Bertocchi A, Mahajan VS, Aicher T, Arnold J, Benson MD, Morningstar J, Barmettler S, Yuen G, Murphy SJH, Walter JE, Ghebremichael M, ... Shalek AK, et al. Induction of metabolic quiescence defines the transitional to follicular B cell switch. Science Signaling. 12. PMID 31641080 DOI: 10.1126/Scisignal.Aaw5573 |
0.382 |
|
2019 |
Barrett NA, Shalek AK. Revisiting Airway Epithelial Remodeling in Type 2 Immunity: Beyond Goblet Cell Metaplasia. The Journal of Allergy and Clinical Immunology. PMID 31600548 DOI: 10.1016/J.Jaci.2019.09.017 |
0.377 |
|
2019 |
Sangesland M, Ronsard L, Kazer SW, Bals J, Boyoglu-Barnum S, Yousif AS, Barnes R, Feldman J, Quirindongo-Crespo M, McTamney PM, Rohrer D, Lonberg N, Chackerian B, Graham BS, Kanekiyo M, ... Shalek AK, et al. Germline-Encoded Affinity for Cognate Antigen Enables Vaccine Amplification of a Human Broadly Neutralizing Response against Influenza Virus. Immunity. PMID 31563464 DOI: 10.1016/J.Immuni.2019.09.001 |
0.304 |
|
2019 |
Tsankov AM, Wadsworth MH, Akopian V, Charlton J, Allon SJ, Arczewska A, Mead BE, Drake RS, Smith ZD, Mikkelsen TS, Shalek AK, Meissner A. Loss of DNA methyltransferase activity in primed human ES cells triggers increased cell-cell variability and transcriptional repression. Development (Cambridge, England). 146. PMID 31515224 DOI: 10.1242/Dev.174722 |
0.434 |
|
2019 |
Reitman ZJ, Paolella BR, Bergthold G, Pelton K, Becker S, Jones R, Sinai CE, Malkin H, Huang Y, Grimmet L, Herbert ZT, Sun Y, Weatherbee JL, Alberta JA, Daley JF, ... ... Shalek AK, et al. Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells. Nature Communications. 10: 3731. PMID 31427603 DOI: 10.1038/S41467-019-11493-2 |
0.44 |
|
2019 |
Gawel DR, Serra-Musach J, Lilja S, Aagesen J, Arenas A, Asking B, Bengnér M, Björkander J, Biggs S, Ernerudh J, Hjortswang H, Karlsson JE, Köpsen M, Lee EJ, Lentini A, ... ... Shalek AK, et al. A validated single-cell-based strategy to identify diagnostic and therapeutic targets in complex diseases. Genome Medicine. 11: 47. PMID 31358043 DOI: 10.1186/S13073-019-0657-3 |
0.419 |
|
2019 |
Smillie CS, Biton M, Ordovas-Montanes J, Sullivan KM, Burgin G, Graham DB, Herbst RH, Rogel N, Slyper M, Waldman J, Sud M, Andrews E, Velonias G, Haber AL, Jagadeesh K, ... ... Shalek AK, et al. Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis. Cell. 178: 714-730.e22. PMID 31348891 DOI: 10.1016/J.Cell.2019.06.029 |
0.441 |
|
2019 |
Ardain A, Domingo-Gonzalez R, Das S, Kazer SW, Howard NC, Singh A, Ahmed M, Nhamoyebonde S, Rangel-Moreno J, Ogongo P, Lu L, Ramsuran D, de la Luz Garcia-Hernandez M, Ulland TK, Darby M, ... ... Shalek AK, et al. Publisher Correction: Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis. Nature. PMID 31337923 DOI: 10.1038/S41586-019-1458-Y |
0.321 |
|
2019 |
Ardain A, Domingo-Gonzalez R, Das S, Kazer SW, Howard NC, Singh A, Ahmed M, Nhamoyebonde S, Rangel-Moreno J, Ogongo P, Lu L, Ramsuran D, de la Luz Garcia-Hernandez M, K Ulland T, Darby M, ... ... Shalek AK, et al. Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis. Nature. PMID 31168092 DOI: 10.1038/S41586-019-1276-2 |
0.308 |
|
2019 |
Ndhlovu ZM, Kazer SW, Nkosi T, Ogunshola F, Muema DM, Anmole G, Swann SA, Moodley A, Dong K, Reddy T, Brockman MA, Shalek AK, Ndung'u T, Walker BD. Augmentation of HIV-specific T cell function by immediate treatment of hyperacute HIV-1 infection. Science Translational Medicine. 11. PMID 31118290 DOI: 10.1126/Scitranslmed.Aau0528 |
0.335 |
|
2019 |
Pepe-Mooney BJ, Dill MT, Alemany A, Ordovas-Montanes J, Matsushita Y, Rao A, Sen A, Miyazaki M, Anakk S, Dawson PA, Ono N, Shalek AK, van Oudenaarden A, Camargo FD. Single-Cell Analysis of the Liver Epithelium Reveals Dynamic Heterogeneity and an Essential Role for YAP in Homeostasis and Regeneration. Cell Stem Cell. PMID 31080134 DOI: 10.1016/J.Stem.2019.04.004 |
0.372 |
|
2019 |
Lossos C, Liu Y, Kolb KE, Christie AL, van Scoyk A, Prakadan SM, Shigemori K, Stevenson KE, Morrow S, Plana OD, Fraser C, Jones KL, Liu H, Pallasch CP, Modiste R, ... ... Shalek AK, et al. Mechanisms of lymphoma clearance induced by high-dose alkylating agents. Cancer Discovery. PMID 31040105 DOI: 10.1158/2159-8290.Cd-18-1393 |
0.347 |
|
2019 |
Aicher TP, Carroll S, Raddi G, Gierahn T, Wadsworth MH, Hughes TK, Love C, Shalek AK. Seq-Well: A Sample-Efficient, Portable Picowell Platform for Massively Parallel Single-Cell RNA Sequencing. Methods in Molecular Biology (Clifton, N.J.). 1979: 111-132. PMID 31028635 DOI: 10.1007/978-1-4939-9240-9_8 |
0.427 |
|
2019 |
van Galen P, Hovestadt V, Wadsworth Ii MH, Hughes TK, Griffin GK, Battaglia S, Verga JA, Stephansky J, Pastika TJ, Lombardi Story J, Pinkus GS, Pozdnyakova O, Galinsky I, Stone RM, Graubert TA, ... Shalek AK, et al. Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity. Cell. PMID 30827681 DOI: 10.1016/J.Cell.2019.01.031 |
0.509 |
|
2019 |
Hamza B, Ng SR, Prakadan SM, Delgado FF, Chin CR, King EM, Yang LF, Davidson SM, DeGouveia KL, Cermak N, Navia AW, Winter PS, Drake RS, Tammela T, Li CM, ... ... Shalek AK, et al. Optofluidic real-time cell sorter for longitudinal CTC studies in mouse models of cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 30674677 DOI: 10.1073/Pnas.1814102116 |
0.378 |
|
2019 |
Shalek AK. Baring cellular souls. Science Translational Medicine. 9. PMID 28202776 DOI: 10.1126/Scitranslmed.Aam6064 |
0.301 |
|
2019 |
Jerby L, Shah P, Cuoco MS, Rodman C, Su M, Melms JM, Leeson R, Kanodia A, Mei S, Lin J, Wang S, Rabasha B, Liu D, Zhang G, Margolais C, ... ... Shalek AK, et al. Abstract A082: Single-cell RNA-sequencing of metastatic melanoma identifies a cancer cell-intrinsic program associated with immune checkpoint inhibitor resistance Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-A082 |
0.441 |
|
2019 |
Murakami MA, Winter PS, Navia AW, Bilal LL, Strouf H, Shigemori K, Gupta A, Mirza M, Leahy CS, Calistri N, Jones K, Scoyk AV, Liu H, Powers F, Kimmerling R, ... ... Shalek AK, et al. Abstract 2450: Single-cell profiling reveals programs mediating oncogenic kinase-independence and minimal residual disease in BCR-ABL-rearranged acute lymphoblastic leukemia Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-2450 |
0.328 |
|
2019 |
Raghavan S, Winter PS, Navia A, Kalekar R, Galvez-Reyes J, Prakadan S, Wang J, Reilly E, Brais L, Cleary JM, Nowak J, Wolpin BM, Shalek AK, Aguirre AJ, Hahn WC. Abstract PR15: Assessment of tumor heterogeneity, clonal evolution, and the stromal microenvironment in metastatic pancreatic ductal adenocarcinoma and matched patient-derived organoids Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-Pr15 |
0.377 |
|
2019 |
Reitman ZJ, Paolella B, Bergthold G, Pelton K, Jones R, Becker S, Sinai CE, Malkin H, Huang Y, Grimmett L, Herbert ZT, Sun Y, Weatherbee J, Alberta J, Daley J, ... ... Shalek AK, et al. Abstract 3647: Single cell RNA sequencing reveals mitogenic and progenitor gene programs inBRAF-rearranged pilocytic astrocytomas Cancer Research. 79: 3647-3647. DOI: 10.1158/1538-7445.Am2019-3647 |
0.454 |
|
2019 |
Ocwieja K, Stanton A, Richards A, Antonucci J, Hughes T, Shalek A, Jaenisch R, Gehrke L. 973. Single-cell RNA Sequencing Analysis of Zika Virus Infection in Human Stem Cell-Derived Cerebral Organoids Open Forum Infectious Diseases. 6: S33-S34. DOI: 10.1093/Ofid/Ofz359.075 |
0.427 |
|
2019 |
Reitman Z, Paolella B, Bergthold G, Pelton K, Becker S, Jones R, Sinai C, Malkin H, Huang Y, Grimmet L, Herbert Z, Sun Y, Weatherbee J, Qian K, Condurat A, ... ... Shalek A, et al. LGG-05. SINGLE CELL RNA SEQUENCING REVEALS MITOGENIC AND PROGENITOR GENE PROGRAMS IN BRAF-REARRANGED PILOCYTIC ASTROCYTOMAS Neuro-Oncology. 21: ii99-ii99. DOI: 10.1093/Neuonc/Noz036.148 |
0.393 |
|
2019 |
Zheng H, Ordovas-Montanes J, Doran B, Yu A, Betz K, Cribbin K, Tkachev V, Colonna L, Furlan S, Dean C, Bratrude B, Suskind D, Lee D, Wahbeh G, Ambartsumyan L, ... Shalek AK, et al. P154 SINGLE-CELL ANALYSIS OF T CELL PATHOGENESIS IN PEDIATRIC CROHN’S DISEASE Gastroenterology. 156: S100. DOI: 10.1053/J.Gastro.2019.01.233 |
0.389 |
|
2019 |
Dwyer DF, Ordovas-Montanes J, Nyquist SK, Buchheit KM, Katz HR, Bhattacharyya N, Laidlaw TM, Boyce JA, Shalek AK, Barrett NA. Mast cell hyperplasia in human type 2 inflammation: insights from single cell RNA sequencing Journal of Allergy and Clinical Immunology. 143: AB178. DOI: 10.1016/J.Jaci.2018.12.546 |
0.437 |
|
2018 |
Douam F, Ziegler CGK, Hrebikova G, Fant B, Leach R, Parsons L, Wang W, Gaska JM, Winer BY, Heller B, Shalek AK, Ploss A. Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses. Nature Communications. 9: 5031. PMID 30487575 DOI: 10.1038/S41467-018-07478-2 |
0.322 |
|
2018 |
Kimmerling RJ, Prakadan SM, Gupta AJ, Calistri NL, Stevens MM, Olcum S, Cermak N, Drake RS, Pelton K, De Smet F, Ligon KL, Shalek AK, Manalis SR. Linking single-cell measurements of mass, growth rate, and gene expression. Genome Biology. 19: 207. PMID 30482222 DOI: 10.1186/S13059-018-1576-0 |
0.432 |
|
2018 |
Biton M, Haber AL, Rogel N, Burgin G, Beyaz S, Schnell A, Ashenberg O, Su CW, Smillie C, Shekhar K, Chen Z, Wu C, Ordovas-Montanes J, Alvarez D, Herbst RH, ... ... Shalek AK, et al. T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation. Cell. PMID 30392957 DOI: 10.1016/J.Cell.2018.10.008 |
0.47 |
|
2018 |
Jerby-Arnon L, Shah P, Cuoco MS, Rodman C, Su MJ, Melms JC, Leeson R, Kanodia A, Mei S, Lin JR, Wang S, Rabasha B, Liu D, Zhang G, Margolais C, ... ... Shalek AK, et al. A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade. Cell. 175: 984-997.e24. PMID 30388455 DOI: 10.1016/J.Cell.2018.09.006 |
0.431 |
|
2018 |
Ordovas-Montanes J, Dwyer DF, Nyquist SK, Buchheit KM, Vukovic M, Deb C, Wadsworth MH, Hughes TK, Kazer SW, Yoshimoto E, Cahill KN, Bhattacharyya N, Katz HR, Berger B, Laidlaw TM, ... ... Shalek AK, et al. Allergic inflammatory memory in human respiratory epithelial progenitor cells. Nature. PMID 30135581 DOI: 10.1038/S41586-018-0449-8 |
0.462 |
|
2018 |
Mead BE, Ordovas-Montanes J, Braun AP, Levy LE, Bhargava P, Szucs MJ, Ammendolia DA, MacMullan MA, Yin X, Hughes TK, Wadsworth MH, Ahmad R, Rakoff-Nahoum S, Carr SA, Langer R, ... ... Shalek AK, et al. Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types. Bmc Biology. 16: 62. PMID 29871632 DOI: 10.1186/S12915-018-0527-2 |
0.431 |
|
2018 |
Martin-Gayo E, Cole MB, Kolb KE, Ouyang Z, Cronin J, Kazer SW, Ordovas-Montanes J, Lichterfeld M, Walker BD, Yosef N, Shalek AK, Yu XG. A Reproducibility-Based Computational Framework Identifies an Inducible, Enhanced Antiviral State in Dendritic Cells from HIV-1 Elite Controllers. Genome Biology. 19: 10. PMID 29378643 DOI: 10.1186/S13059-017-1385-X |
0.406 |
|
2018 |
Shalek AK. Size no longer matters. Science Translational Medicine. 8: 365ec185. PMID 27856794 DOI: 10.1126/Scitranslmed.Aal0073 |
0.434 |
|
2018 |
Van Galen P, Hovestadt V, Wadsworth II M, Hughes T, Griffin GK, Verga JA, Stephansky J, Pastika TJ, Lombardi Story J, Pinkus GS, Pozdnyakova O, Galinsky I, Stone RM, Graubert TA, Shalek AK, et al. Single-Cell RNA-Seq Reveals AML Cellular Hierarchies Relevant to Clinical Outcomes and Immunity Blood. 132: 542-542. DOI: 10.1182/Blood-2018-99-113502 |
0.487 |
|
2018 |
Alvarez-Breckenridge C, Prakadan S, Lee E, Tolaney S, Nayak L, Lin N, Bihun I, Chukwueke U, Oh K, White M, Gerstner E, Lawrence D, Cohen J, Giobbie-Hurder A, Cahill D, ... ... Shalek A, et al. CMET-20. EVIDENCE OF CNS RESPONSE OF PEMBROLIZUMAB FOR LEPTOMENINGEAL CARCINOMATOSIS AT A SINGLE CELL RESOLUTION Neuro-Oncology. 20: vi57-vi58. DOI: 10.1093/Neuonc/Noy148.232 |
0.392 |
|
2018 |
Reitman Z, Paolella B, Bergthold G, Pelton K, Becker S, Jones R, Herbert Z, Grimmett L, Daley J, Filbin M, Suva M, Goumnerova L, Wright K, Chi S, Kieran M, ... ... Shalek A, et al. LGG-13. RESOLVING TRANSCRIPTIONAL PROFILES IN BRAF-REARRANGED PILOCYTIC ASTROCYTOMA USING SINGLE CELL RNA SEQUENCING Neuro-Oncology. 20: i107-i107. DOI: 10.1093/Neuonc/Noy059.355 |
0.396 |
|
2018 |
van Galen P, Hovestadt V, Griffin G, Verga J, Wadsworth M, Hughes T, Stephansky J, Pastika T, Story JL, Pinkus G, Pozdnyakova O, Graubert T, Shalek A, Aster J, Lane A, et al. Single-Cell Analysis of AML Reveals Determinants of Disease Progression and Immune Evasion Experimental Hematology. 64: S47. DOI: 10.1016/J.Exphem.2018.06.060 |
0.408 |
|
2017 |
Gaya M, Barral P, Burbage M, Aggarwal S, Montaner B, Warren Navia A, Aid M, Tsui C, Maldonado P, Nair U, Ghneim K, Fallon PG, Sekaly RP, Barouch DH, Shalek AK, et al. Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells. Cell. PMID 29249358 DOI: 10.1016/J.Cell.2017.11.036 |
0.419 |
|
2017 |
Regev A, Teichmann SA, Lander ES, Amit I, Benoist C, Birney E, Bodenmiller B, Campbell PJ, Carninci P, Clatworthy M, Clevers H, Deplancke B, Dunham I, Eberwine J, Eils R, ... ... Shalek AK, et al. Science Forum: The Human Cell Atlas. Elife. 6. PMID 29206104 DOI: 10.7554/Elife.27041 |
0.423 |
|
2017 |
Shalek AK, Benson M. Single-cell analyses to tailor treatments. Science Translational Medicine. 9. PMID 28931656 DOI: 10.1126/Scitranslmed.Aan4730 |
0.454 |
|
2017 |
Nirschl CJ, Suárez-Fariñas M, Izar B, Prakadan S, Dannenfelser R, Tirosh I, Liu Y, Zhu Q, Devi KSP, Carroll SL, Chau D, Rezaee M, Kim TG, Huang R, Fuentes-Duculan J, ... ... Shalek AK, et al. IFNγ-Dependent Tissue-Immune Homeostasis Is Co-opted in the Tumor Microenvironment. Cell. 170: 127-141.e15. PMID 28666115 DOI: 10.1016/J.Cell.2017.06.016 |
0.368 |
|
2017 |
Prakadan SM, Shalek AK, Weitz DA. Scaling by shrinking: empowering single-cell 'omics' with microfluidic devices. Nature Reviews. Genetics. PMID 28392571 DOI: 10.1038/Nrg.2017.15 |
0.437 |
|
2017 |
Gierahn TM, Wadsworth MH, Hughes TK, Bryson BD, Butler A, Satija R, Fortune S, Love JC, Shalek AK. Seq-Well: portable, low-cost RNA sequencing of single cells at high throughput. Nature Methods. PMID 28192419 DOI: 10.1038/Nmeth.4179 |
0.43 |
|
2017 |
Martin-Gayo E, Cronin J, Hickman T, Ouyang Z, Lindqvist M, Kolb KE, Schulze Zur Wiesch J, Cubas R, Porichis F, Shalek AK, van Lunzen J, Haddad EK, Walker BD, Kaufmann DE, Lichterfeld M, et al. Circulating CXCR5(+)CXCR3(+)PD-1(lo) Tfh-like cells in HIV-1 controllers with neutralizing antibody breadth. Jci Insight. 2: e89574. PMID 28138558 DOI: 10.1172/Jci.Insight.89574 |
0.378 |
|
2017 |
Regev A, Teichmann SA, Lander ES, Amit I, Benoist C, Birney E, Bodenmiller B, Campbell P, Carninci P, Clatworthy M, Clevers H, Deplancke B, Dunham I, Eberwine J, Eils R, ... ... Shalek A, et al. Author response: The Human Cell Atlas Elife. DOI: 10.7554/Elife.27041.011 |
0.362 |
|
2017 |
Miller BC, Wadsworth MH, Bi K, Hughes TK, Sharpe AH, Shalek AK, Haining WN. Abstract PR11: Dissecting mechanisms of PD-1 blockade with single-cell RNA-sequencing Cancer Immunology Research. 5. DOI: 10.1158/2326-6074.Tumimm16-Pr11 |
0.423 |
|
2017 |
Izar B, Stover E, Tirosh I, Rotem A, Shah P, Rodman C, Prakadan S, Wadsworth M, Su M, Leeson R, Palakurthi S, Liu J, Matulonis U, Shalek A, Rozenblatt-Rosen O, et al. Abstract AP19: SINGLE–CELL RNA–SEQUENCING OF PATIENT–DERIVED OVARIAN CANCER CELLS AND PATIENT–DERIVED XENOGRAFT MODELS Clinical Cancer Research. 23. DOI: 10.1158/1557-3265.Ovcasymp16-Ap19 |
0.48 |
|
2017 |
Miller BC, Wadsworth MH, Bi K, Hughes TK, Manguso R, Sharpe AH, Shalek AK, Haining N. Abstract 3027: Dissecting mechanisms of anti-PD-1 therapy with massively parallel single-cell RNA-sequencing Immunology. 77: 3027-3027. DOI: 10.1158/1538-7445.Am2017-3027 |
0.328 |
|
2017 |
Paolella B, Bandopadhayay P, Bergthold G, Shalek A, Pelton K, Ramkissoon S, Sinai C, Malkin H, Herbert Z, Sun Y, Alberta J, Brown M, Daley J, Lazo-Kallanian S, Goumnerova L, et al. LGG-05. SINGLE-CELL RNA SEQUENCING OF PEDIATRIC LOW-GRADE GLIOMAS REVEALS INTRATUMORAL HETEROGENEITY Neuro-Oncology. 19: iv33-iv34. DOI: 10.1093/Neuonc/Nox083.138 |
0.384 |
|
2016 |
Ranasinghe S, Lamothe PA, Soghoian DZ, Kazer SW, Cole MB, Shalek AK, Yosef N, Jones RB, Donaghey F, Nwonu C, Jani P, Clayton GM, Crawford F, White J, Montoya A, et al. Antiviral CD8(+) T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion. Immunity. 45: 917-930. PMID 27760342 DOI: 10.1016/J.Immuni.2016.09.015 |
0.343 |
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2016 |
Genshaft AS, Li S, Gallant CJ, Darmanis S, Prakadan SM, Ziegler CG, Lundberg M, Fredriksson S, Hong J, Regev A, Livak KJ, Landegren U, Shalek AK. Multiplexed, targeted profiling of single-cell proteomes and transcriptomes in a single reaction. Genome Biology. 17: 188. PMID 27640647 DOI: 10.1186/S13059-016-1045-6 |
0.41 |
|
2016 |
Tirosh I, Izar B, Prakadan SM, Wadsworth MH, Treacy D, Trombetta JJ, Rotem A, Rodman C, Lian C, Murphy G, Fallahi-Sichani M, Dutton-Regester K, Lin JR, Cohen O, Shah P, ... ... Shalek AK, et al. Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq. Science (New York, N.Y.). 352: 189-196. PMID 27124452 DOI: 10.1126/Science.Aad0501 |
0.482 |
|
2016 |
Wong AS, Choi GC, Cui CH, Pregernig G, Milani P, Adam M, Perli SD, Kazer SW, Gaillard A, Hermann M, Shalek AK, Fraenkel E, Lu TK. Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM. Proceedings of the National Academy of Sciences of the United States of America. PMID 26864203 DOI: 10.1073/Pnas.1517883113 |
0.385 |
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2016 |
Kløverpris HN, Kazer SW, Mjösberg J, Mabuka JM, Wellmann A, Ndhlovu Z, Yadon MC, Nhamoyebonde S, Muenchhoff M, Simoni Y, Andersson F, Kuhn W, Garrett N, Burgers WA, Kamya P, ... ... Shalek AK, et al. Innate Lymphoid Cells Are Depleted Irreversibly during Acute HIV-1 Infection in the Absence of Viral Suppression. Immunity. PMID 26850658 DOI: 10.1016/J.Immuni.2016.01.006 |
0.326 |
|
2016 |
Kimmerling RJ, Lee Szeto G, Li JW, Genshaft AS, Kazer SW, Payer KR, de Riba Borrajo J, Blainey PC, Irvine DJ, Shalek AK, Manalis SR. A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages. Nature Communications. 7: 10220. PMID 26732280 DOI: 10.1038/Ncomms10220 |
0.495 |
|
2016 |
Izar B, Tirosh I, Prakadan S, Wadsworth M, Rotem A, Trombetta J, Shah P, Dutton-Regester K, Fallahi M, Ren-Lin J, Murphy G, Lian C, Sorger P, Bertagnolli MM, Rozenblatt-Rosen O, ... ... Shalek A, et al. Implementation of single-cell genomics as a translational tool in patients with metastatic melanoma. Journal of Clinical Oncology. 34: 11503-11503. DOI: 10.1200/Jco.2016.34.15_Suppl.11503 |
0.319 |
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2016 |
Izar B, Tirsh I, Prakadan S, Wadsworth M, Treacy D, Trombetta J, Rotem A, Lian C, Murphy G, Fallahi-Sichani M, Dutton-Regester K, Lin J, Jane-Valbuena J, Rozenblatt-Rosen O, Yoon C, ... Shalek A, et al. Abstract 4380: Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-sequencing Cancer Research. 76: 4380-4380. DOI: 10.1158/1538-7445.Am2016-4380 |
0.506 |
|
2016 |
Shalek AK. A basic strategy for detecting CD8 T cell specificity Science Translational Medicine. 8: 359ec161-359ec161. DOI: 10.1126/Scitranslmed.Aai8748 |
0.38 |
|
2016 |
Shalek AK. On the right track Science Translational Medicine. 8: 353ec136-353ec136. DOI: 10.1126/Scitranslmed.Aah5500 |
0.343 |
|
2016 |
Shalek AK. Made-by-measure Science Translational Medicine. 8: 341ec89-341ec89. DOI: 10.1126/Scitranslmed.Aag1705 |
0.4 |
|
2016 |
Miller B, Wadsworth M, Bi K, Hughes T, Sharpe A, Shalek A, Haining W. Single-Cell RNA-Seq Allows Deep Analysis of the Tumor Immune Microenvironment and Alterations Induced by Anti-PD-1 Treatment Clinical Lymphoma Myeloma and Leukemia. 16: S127. DOI: 10.1016/J.Clml.2016.07.187 |
0.364 |
|
2015 |
Finak G, McDavid A, Yajima M, Deng J, Gersuk V, Shalek AK, Slichter CK, Miller HW, McElrath MJ, Prlic M, Linsley PS, Gottardo R. MAST: a flexible statistical framework for assessing transcriptional changes and characterizing heterogeneity in single-cell RNA sequencing data. Genome Biology. 16: 278. PMID 26653891 DOI: 10.1186/S13059-015-0844-5 |
0.404 |
|
2015 |
Gaublomme JT, Yosef N, Lee Y, Gertner RS, Yang LV, Wu C, Pandolfi PP, Mak T, Satija R, Shalek AK, Kuchroo VK, Park H, Regev A. Single-Cell Genomics Unveils Critical Regulators of Th17 Cell Pathogenicity. Cell. PMID 26607794 DOI: 10.1016/J.Cell.2015.11.009 |
0.573 |
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2015 |
Shakya A, Goren A, Shalek A, German CN, Snook J, Kuchroo VK, Yosef N, Chan RC, Regev A, Williams MA, Tantin D. Oct1 and OCA-B are selectively required for CD4 memory T cell function. The Journal of Experimental Medicine. PMID 26481684 DOI: 10.1084/Jem.20150363 |
0.316 |
|
2015 |
Avraham R, Haseley N, Brown D, Penaranda C, Jijon HB, Trombetta JJ, Satija R, Shalek AK, Xavier RJ, Regev A, Hung DT. Pathogen Cell-to-Cell Variability Drives Heterogeneity in Host Immune Responses. Cell. 162: 1309-21. PMID 26343579 DOI: 10.1016/J.Cell.2015.08.027 |
0.396 |
|
2015 |
Wadsworth MH, Hughes TK, Shalek AK. Marrying microfluidics and microwells for parallel, high-throughput single-cell genomics. Genome Biology. 16: 129. PMID 26087845 DOI: 10.1186/S13059-015-0695-0 |
0.39 |
|
2015 |
Macosko EZ, Basu A, Satija R, Nemesh J, Shekhar K, Goldman M, Tirosh I, Bialas AR, Kamitaki N, Martersteck EM, Trombetta JJ, Weitz DA, Sanes JR, Shalek AK, Regev A, et al. Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets. Cell. 161: 1202-14. PMID 26000488 DOI: 10.1016/J.Cell.2015.05.002 |
0.495 |
|
2015 |
Tirosh I, Izar B, Prakadan SM, Wadsworth MH, Treacy D, Trombetta JJ, Lu D, Rotem A, Lian C, Murphy G, Cohen O, Allen Ev, Bertagnolli M, Genshaft A, Hughes TK, ... ... Shalek AK, et al. Abstract CN07-04: Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-Cn07-04 |
0.468 |
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2015 |
Avraham R, Haseley N, Brown D, Penaranda C, Jijon HB, Trombetta JJ, Satija R, Shalek AK, Xavier RJ, Regev A, Hung DT. Erratum: Pathogen cell-to-cell variability drives heterogeneity in host immune responses ((Cell (2015) 162 (1309-1321)) Cell. 163. DOI: 10.1016/J.Cell.2015.09.044 |
0.424 |
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2014 |
Kumar RM, Cahan P, Shalek AK, Satija R, DaleyKeyser AJ, Li H, Zhang J, Pardee K, Gennert D, Trombetta JJ, Ferrante TC, Regev A, Daley GQ, Collins JJ. Deconstructing transcriptional heterogeneity in pluripotent stem cells. Nature. 516: 56-61. PMID 25471879 DOI: 10.1038/Nature13920 |
0.368 |
|
2014 |
Trombetta JJ, Gennert D, Lu D, Satija R, Shalek AK, Regev A. Preparation of Single-Cell RNA-Seq Libraries for Next Generation Sequencing. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. 107: 4.22.1-4.22.17. PMID 24984854 DOI: 10.1002/0471142727.Mb0422S107 |
0.418 |
|
2014 |
Patel AP, Tirosh I, Trombetta JJ, Shalek AK, Gillespie SM, Wakimoto H, Cahill DP, Nahed BV, Curry WT, Martuza RL, Louis DN, Rozenblatt-Rosen O, Suvà ML, Regev A, Bernstein BE. Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma. Science (New York, N.Y.). 344: 1396-401. PMID 24925914 DOI: 10.1126/Science.1254257 |
0.469 |
|
2014 |
Shalek AK, Satija R, Shuga J, Trombetta JJ, Gennert D, Lu D, Chen P, Gertner RS, Gaublomme JT, Yosef N, Schwartz S, Fowler B, Weaver S, Wang J, Wang X, et al. Single-cell RNA-seq reveals dynamic paracrine control of cellular variation. Nature. 510: 363-9. PMID 24919153 DOI: 10.1038/Nature13437 |
0.612 |
|
2014 |
Wang L, Shalek AK, Lawrence M, Ding R, Gaublomme JT, Pochet N, Stojanov P, Sougnez C, Shukla SA, Stevenson KE, Zhang W, Wong J, Sievers QL, MacDonald BT, Vartanov AR, et al. Somatic mutation as a mechanism of Wnt/β-catenin pathway activation in CLL. Blood. 124: 1089-98. PMID 24778153 DOI: 10.1182/Blood-2014-01-552067 |
0.466 |
|
2014 |
Lohr JG, Adalsteinsson VA, Cibulskis K, Choudhury AD, Rosenberg M, Cruz-Gordillo P, Francis JM, Zhang CZ, Shalek AK, Satija R, Trombetta JJ, Lu D, Tallapragada N, Tahirova N, Kim S, et al. Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer. Nature Biotechnology. 32: 479-84. PMID 24752078 DOI: 10.1038/Nbt.2892 |
0.325 |
|
2014 |
Satija R, Shalek AK. Heterogeneity in immune responses: from populations to single cells. Trends in Immunology. 35: 219-29. PMID 24746883 DOI: 10.1016/J.It.2014.03.004 |
0.396 |
|
2014 |
Suvà ML, Rheinbay E, Gillespie SM, Patel AP, Wakimoto H, Rabkin SD, Riggi N, Chi AS, Cahill DP, Nahed BV, Curry WT, Martuza RL, Rivera MN, Rossetti N, Kasif S, ... ... Shalek AK, et al. Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells. Cell. 157: 580-94. PMID 24726434 DOI: 10.1016/J.Cell.2014.02.030 |
0.373 |
|
2014 |
Adalsteinsson VA, Lohr JG, Cibulskis K, Choudhury AD, Rosenberg M, Cruz-Gordillo P, Francis J, Zhang C, Shalek AK, Satija R, Trombetta JT, Lu D, Tallapragada N, Tahirova NT, Kim S, et al. Abstract 993: Whole exome sequencing of CTCs as a window into metastatic cancer Cancer Research. 74: 993-993. DOI: 10.1158/1538-7445.Am2014-993 |
0.306 |
|
2013 |
Shalek AK, Satija R, Adiconis X, Gertner RS, Gaublomme JT, Raychowdhury R, Schwartz S, Yosef N, Malboeuf C, Lu D, Trombetta JJ, Gennert D, Gnirke A, Goren A, Hacohen N, et al. Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells. Nature. 498: 236-40. PMID 23685454 DOI: 10.1038/Nature12172 |
0.609 |
|
2013 |
Gifford CA, Ziller MJ, Gu H, Trapnell C, Donaghey J, Tsankov A, Shalek AK, Kelley DR, Shishkin AA, Issner R, Zhang X, Coyne M, Fostel JL, Holmes L, Meldrim J, et al. Transcriptional and epigenetic dynamics during specification of human embryonic stem cells. Cell. 153: 1149-63. PMID 23664763 DOI: 10.1016/J.Cell.2013.04.037 |
0.497 |
|
2013 |
Gat-Viks I, Chevrier N, Wilentzik R, Eisenhaure T, Raychowdhury R, Steuerman Y, Shalek AK, Hacohen N, Amit I, Regev A. Deciphering molecular circuits from genetic variation underlying transcriptional responsiveness to stimuli. Nature Biotechnology. 31: 342-9. PMID 23503680 DOI: 10.1038/Nbt.2519 |
0.326 |
|
2013 |
Yosef N, Shalek AK, Gaublomme JT, Jin H, Lee Y, Awasthi A, Wu C, Karwacz K, Xiao S, Jorgolli M, Gennert D, Satija R, Shakya A, Lu DY, Trombetta JJ, et al. Dynamic regulatory network controlling TH17 cell differentiation. Nature. 496: 461-8. PMID 23467089 DOI: 10.1038/Nature11981 |
0.531 |
|
2013 |
Na YR, Kim SY, Gaublomme JT, Shalek AK, Jorgolli M, Park H, Yang EG. Probing enzymatic activity inside living cells using a nanowire-cell "sandwich" assay. Nano Letters. 13: 153-8. PMID 23244056 DOI: 10.1021/Nl3037068 |
0.505 |
|
2012 |
Shalek AK, Gaublomme JT, Wang L, Yosef N, Chevrier N, Andersen MS, Robinson JT, Pochet N, Neuberg D, Gertner RS, Amit I, Brown JR, Hacohen N, Regev A, Wu CJ, et al. Nanowire-mediated delivery enables functional interrogation of primary immune cells: application to the analysis of chronic lymphocytic leukemia. Nano Letters. 12: 6498-504. PMID 23190424 DOI: 10.1021/Nl3042917 |
0.693 |
|
2012 |
Robinson JT, Jorgolli M, Shalek AK, Yoon MH, Gertner RS, Park H. Vertical nanowire electrode arrays as a scalable platform for intracellular interfacing to neuronal circuits. Nature Nanotechnology. 7: 180-4. PMID 22231664 DOI: 10.1038/Nnano.2011.249 |
0.602 |
|
2011 |
Chevrier N, Mertins P, Artyomov MN, Shalek AK, Iannacone M, Ciaccio MF, Gat-Viks I, Tonti E, DeGrace MM, Clauser KR, Garber M, Eisenhaure TM, Yosef N, Robinson J, Sutton A, et al. Systematic discovery of TLR signaling components delineates viral-sensing circuits. Cell. 147: 853-67. PMID 22078882 DOI: 10.1016/J.Cell.2011.10.022 |
0.643 |
|
2011 |
Wang L, Shalek AK, Gaublomme J, Yosef N, Brown JR, Neuberg D, Hacohen N, Park H, Wu CJ. Sensitivity to Wnt Pathway Inhibition in CLL Is Associated with Specific Gene Expression Signatures Blood. 118: 801-801. DOI: 10.1182/Blood.V118.21.801.801 |
0.551 |
|
2010 |
Shalek AK, Robinson JT, Karp ES, Lee JS, Ahn DR, Yoon MH, Sutton A, Jorgolli M, Gertner RS, Gujral TS, MacBeath G, Yang EG, Park H. Vertical silicon nanowires as a universal platform for delivering biomolecules into living cells. Proceedings of the National Academy of Sciences of the United States of America. 107: 1870-5. PMID 20080678 DOI: 10.1073/Pnas.0909350107 |
0.674 |
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