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Beth A. Weaver, Ph.D. - Publications

Affiliations: 
University of California, San Diego, La Jolla, CA 
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54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Zhou AS, Tucker JB, Scribano CM, Lynch AR, Carlsen CL, Pop-Vicas ST, Pattaswamy SM, Burkard ME, Weaver BA. Diverse microtubule-targeted anticancer agents kill cells by inducing chromosome missegregation on multipolar spindles. Plos Biology. 21: e3002339. PMID 37883329 DOI: 10.1371/journal.pbio.3002339  0.367
2023 Lynch AR, Bradford S, Zhou AS, Oxendine K, Henderson L, Horner VL, Weaver BA, Burkard ME. A survey of CIN measures across mechanistic models. Biorxiv : the Preprint Server For Biology. PMID 37398147 DOI: 10.1101/2023.06.15.544840  0.383
2023 Cosper PF, Hrycyniak LCF, Paracha M, Lee DL, Wan J, Jones K, Bice SA, Nickel K, Mallick S, Taylor AM, Kimple RJ, Lambert PF, Weaver BA. HPV16 E6 induces chromosomal instability due to polar chromosomes caused by E6AP-dependent degradation of the mitotic kinesin CENP-E. Proceedings of the National Academy of Sciences of the United States of America. 120: e2216700120. PMID 36989302 DOI: 10.1073/pnas.2216700120  0.387
2023 Tucker JB, Bonema SC, García-Varela R, Denu RA, Hu Y, McGregor SM, Burkard ME, Weaver BA. Misaligned Chromosomes are a Major Source of Chromosomal Instability in Breast Cancer. Cancer Research Communications. 3: 54-65. PMID 36968230 DOI: 10.1158/2767-9764.CRC-22-0302  0.41
2022 Lynch AR, Arp NL, Zhou AS, Weaver BA, Burkard ME. Quantifying chromosomal instability from intratumoral karyotype diversity using agent-based modeling and Bayesian inference. Elife. 11. PMID 35380536 DOI: 10.7554/eLife.69799  0.4
2022 Cosper PF, Copeland SE, Tucker JB, Weaver BA. Chromosome Missegregation as a Modulator of Radiation Sensitivity. Seminars in Radiation Oncology. 32: 54-63. PMID 34861996 DOI: 10.1016/j.semradonc.2021.09.002  0.408
2021 Scribano CM, Wan J, Esbona K, Tucker JB, Lasek A, Zhou AS, Zasadil LM, Molini R, Fitzgerald J, Lager AM, Laffin JJ, Correia-Staudt K, Wisinski KB, Tevaarwerk AJ, O'Regan R, ... ... Weaver BA, et al. Chromosomal instability sensitizes patient breast tumors to multipolar divisions induced by paclitaxel. Science Translational Medicine. 13: eabd4811. PMID 34516829 DOI: 10.1126/scitranslmed.abd4811  0.347
2020 Funk LC, Wan J, Ryan SD, Kaur C, Sullivan R, Roopra A, Weaver BA. p53 is not required for cell death and tumor suppression caused by high chromosomal instability. Molecular Cancer Research : McR. PMID 32948674 DOI: 10.1158/1541-7786.Mcr-20-0488  0.483
2020 Jin N, Lera RF, Yan RE, Guo F, Oxendine K, Horner VL, Hu Y, Wan J, Mattison RJ, Weaver BA, Burkard ME. Chromosomal instability upregulates interferon in acute myeloid leukemia. Genes, Chromosomes & Cancer. PMID 32557940 DOI: 10.1002/Gcc.22880  0.474
2020 Singh A, Denu RA, Wolfe SK, Sperger JM, Schehr J, Witkowsky T, Esbona K, Chappell RJ, Weaver BA, Burkard ME, Lang JM. Centrosome amplification is a frequent event in circulating tumor cells from subjects with metastatic breast cancer. Molecular Oncology. PMID 32255253 DOI: 10.1002/1878-0261.12687  0.337
2020 Johnson JM, Hebert AS, Drane QH, Lera RF, Wan J, Weaver BA, Coon JJ, Burkard ME. A Genetic Toggle for Chemical Control of Individual Plk1 Substrates. Cell Chemical Biology. PMID 32017920 DOI: 10.1016/J.Chembiol.2020.01.007  0.348
2020 Cosper P, Funk L, Yin Q, Wan J, Kimple R, Weaver B. Characterization of Chromosomal Instability and its Effect on Radiation Sensitivity in Head and Neck Cancer International Journal of Radiation Oncology*Biology*Physics. 106: 1186. DOI: 10.1016/J.Ijrobp.2019.11.121  0.391
2019 Denomy C, Germain S, Haave B, Vizeacoumar FS, Freywald A, Weaver BA, Vizeacoumar FJ. Banding Together: A Systematic Comparison of The Cancer Genome Atlas and the Mitelman Database. Cancer Research. PMID 31416843 DOI: 10.1158/0008-5472.Can-19-0585  0.439
2019 Wan J, Block S, Scribano CM, Thiry R, Esbona K, Audhya A, Weaver BA. Mad1 destabilizes p53 by preventing PML from sequestering MDM2. Nature Communications. 10: 1540. PMID 30948704 DOI: 10.1038/S41467-019-09471-9  0.399
2019 Cosper P, Funk L, Kimple R, Weaver B. Chromosomal Instability Increases Radiation Sensitivity in Head and Neck Cancer International Journal of Radiation Oncology*Biology*Physics. 105: S166. DOI: 10.1016/J.Ijrobp.2019.06.191  0.393
2018 Esbona K, Jin N, Correia-Staudt K, Lager A, Heidke T, Laffin J, Weaver B, Burkard M. Abstract P4-03-09: Chromosomal instability predicts taxane sensitivity in breast cancer Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P4-03-09  0.451
2018 Wan J, Weaver BA. Abstract 4290: Mad1 promotes tumor progression through destabilization of p53 Cancer Research. 78: 4290-4290. DOI: 10.1158/1538-7445.Am2018-4290  0.443
2018 Singh A, Denu RA, Sperger JM, Weaver BA, Burkard ME, Lang JM. Abstract 3604: Centrosome amplification in epcam-captured circulating tumor cells from metastatic cancer patients Cancer Research. 78: 3604-3604. DOI: 10.1158/1538-7445.Am2018-3604  0.351
2018 Funk LC, Lee DL, Kimple RJ, Lambert PF, Weaver BA. Abstract 1846: HPV oncoproteins cause specific types of chromosomal instability in head and neck cancer Cancer Research. 78: 1846-1846. DOI: 10.1158/1538-7445.Am2018-1846  0.411
2018 Lasek AL, Britigan EM, Weaver BA. Abstract 1844: Centriole amplification sensitizes cells to paclitaxel Cancer Research. 78: 1844-1844. DOI: 10.1158/1538-7445.Am2018-1844  0.548
2017 Burkard ME, Weaver BA. Tuning Chromosomal Instability to Optimize Tumor Fitness. Cancer Discovery. 7: 134-136. PMID 28167614 DOI: 10.1158/2159-8290.Cd-16-1415  0.54
2017 Singh A, Sperger JM, Schehr J, Witkowski T, Weaver BA, Burkard ME, Lang JM. Abstract 3784: Expression of estrogen receptor specific signaling transcriptome in epithelial cell adhesion molecule (EpCAM) captured circulating tumor cells from patients with breast cancer Cancer Research. 77: 3784-3784. DOI: 10.1158/1538-7445.Am2017-3784  0.34
2016 Funk LC, Zasadil LM, Weaver BA. Living in CIN: Mitotic Infidelity and Its Consequences for Tumor Promotion and Suppression. Developmental Cell. 39: 638-652. PMID 27997823 DOI: 10.1016/J.Devcel.2016.10.023  0.559
2016 Cunningham CE, Li S, Vizeacoumar FS, Bhanumathy KK, Lee JS, Parameswaran S, Furber L, Abuhussein O, Paul JM, McDonald M, Templeton SD, Shukla H, El Zawily AM, Boyd F, Alli N, ... ... Weaver BA, et al. Therapeutic relevance of the protein phosphatase 2A in cancer. Oncotarget. PMID 27557495 DOI: 10.18632/Oncotarget.11399  0.456
2016 Zasadil LM, Britigan EM, Ryan SD, Kaur C, Guckenberger DJ, Beebe DJ, Moser AR, Weaver BA. High rates of chromosome missegregation suppress tumor progression, but do not inhibit tumor initiation. Molecular Biology of the Cell. PMID 27146113 DOI: 10.1091/Mbc.E15-10-0747  0.559
2016 Cavalcante L, Denu R, Zasadil L, Weaver B, Burkard M. Abstract P3-07-53: Chromosomal instability as a predictor of sensitivity to paclitaxel Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-P3-07-53  0.444
2015 Choudhary A, Zachek B, Lera RF, Zasadil LM, Lasek A, Denu RA, Kim H, Kanugh C, Laffin J, Harter JM, Wisinski KB, Saha S, Weaver BA, Burkard ME. Identification of selective lead compounds for treatment of high-ploidy breast cancer. Molecular Cancer Therapeutics. PMID 26586723 DOI: 10.1158/1535-7163.Mct-15-0527  0.396
2015 Wan J, Weaver BA. Mad1 at the Golgi apparatus: a story beyond kinetochores. Cell Cycle (Georgetown, Tex.). 14: 1763-4. PMID 26017778 DOI: 10.1080/15384101.2015.1032639  0.491
2014 Wan J, Zhu F, Zasadil LM, Yu J, Wang L, Johnson A, Berthier E, Beebe DJ, Audhya A, Weaver BA. A Golgi-localized pool of the mitotic checkpoint component Mad1 controls integrin secretion and cell migration. Current Biology : Cb. 24: 2687-92. PMID 25447996 DOI: 10.1016/J.Cub.2014.09.052  0.504
2014 Weaver BA. How Taxol/paclitaxel kills cancer cells. Molecular Biology of the Cell. 25: 2677-81. PMID 25213191 DOI: 10.1091/Mbc.E14-04-0916  0.352
2014 Britigan EM, Wan J, Zasadil LM, Ryan SD, Weaver BA. The ARF tumor suppressor prevents chromosomal instability and ensures mitotic checkpoint fidelity through regulation of Aurora B. Molecular Biology of the Cell. 25: 2761-73. PMID 25057018 DOI: 10.1091/Mbc.E14-05-0966  0.564
2014 Zasadil LM, Andersen KA, Yeum D, Rocque GB, Wilke LG, Tevaarwerk AJ, Raines RT, Burkard ME, Weaver BA. Cytotoxicity of paclitaxel in breast cancer is due to chromosome missegregation on multipolar spindles. Science Translational Medicine. 6: 229ra43. PMID 24670687 DOI: 10.1126/Scitranslmed.3007965  0.526
2014 Burkard ME, Choudhary A, Lera RF, Fedenia R, Kanugh C, Laffin JJ, Zasadil LM, Weaver BA, Wisinski KB. Abstract 2526: Polyploidy: A new breast cancer subtype and a lead compound that targets it with high selectivity Cancer Research. 74: 2526-2526. DOI: 10.1158/1538-7445.Am2014-2526  0.361
2013 Silk AD, Zasadil LM, Holland AJ, Vitre B, Cleveland DW, Weaver BA. Chromosome missegregation rate predicts whether aneuploidy will promote or suppress tumors. Proceedings of the National Academy of Sciences of the United States of America. 110: E4134-41. PMID 24133140 DOI: 10.1073/Pnas.1317042110  0.79
2013 Choudhary A, Lera RF, Martowicz ML, Oxendine K, Laffin JJ, Weaver BA, Burkard ME. Interphase cytofission maintains genomic integrity of human cells after failed cytokinesis. Proceedings of the National Academy of Sciences of the United States of America. 110: 13026-31. PMID 23878225 DOI: 10.1073/Pnas.1308203110  0.403
2013 Zasadil LM, Britigan EM, Weaver BA. 2n or not 2n: Aneuploidy, polyploidy and chromosomal instability in primary and tumor cells. Seminars in Cell & Developmental Biology. 24: 370-9. PMID 23416057 DOI: 10.1016/J.Semcdb.2013.02.001  0.579
2013 Harkness T, Weaver BA, Alexander CM, Ogle BM. Cell fusion in tumor development: accelerated genetic evolution. Critical Reviews in Oncogenesis. 18: 19-42. PMID 23237551 DOI: 10.1615/Critrevoncog.V18.I1-2.30  0.474
2013 Zasadil LM, Burkard M, Weaver BA. Abstract 1750: Clinically relevant paclitaxel concentrations cause chromosome missegregation rather than mitotic arrest. Cancer Research. 73: 1750-1750. DOI: 10.1158/1538-7445.Am2013-1750  0.538
2012 Ryan SD, Britigan EM, Zasadil LM, Witte K, Audhya A, Roopra A, Weaver BA. Up-regulation of the mitotic checkpoint component Mad1 causes chromosomal instability and resistance to microtubule poisons. Proceedings of the National Academy of Sciences of the United States of America. 109: E2205-14. PMID 22778409 DOI: 10.1073/Pnas.1201911109  0.553
2012 Britigan EM, Weaver BA. Abstract LB-289: A novel role for the p19ARF tumor suppressor in chromosome segregation Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-289  0.562
2012 Zasadil LM, Weaver BA. Abstract 3064: An alternative mechanism of action for paclitaxel in breast cancer Cancer Research. 72: 3064-3064. DOI: 10.1158/1538-7445.Am2012-3064  0.494
2009 Weaver BA, Cleveland DW. The role of aneuploidy in promoting and suppressing tumors. The Journal of Cell Biology. 185: 935-7. PMID 19528293 DOI: 10.1083/jcb.200905098  0.53
2008 Weaver BA, Cleveland DW. The aneuploidy paradox in cell growth and tumorigenesis. Cancer Cell. 14: 431-3. PMID 19061834 DOI: 10.1016/J.Ccr.2008.11.011  0.646
2008 Weaver BA, Silk AD, Cleveland DW. Low rates of aneuploidy promote tumorigenesis while high rates of aneuploidy cause cell death and tumor suppression. Cellular Oncology : the Official Journal of the International Society For Cellular Oncology. 30: 453. PMID 18791276 DOI: 10.3233/Clo-2008-0445  0.706
2007 Weaver BA, Cleveland DW. Aneuploidy: instigator and inhibitor of tumorigenesis. Cancer Research. 67: 10103-5. PMID 17974949 DOI: 10.1158/0008-5472.CAN-07-2266  0.65
2007 Weaver BA, Cleveland DW. Comment on "A centrosome-independent role for gamma-TuRC proteins in the spindle assembly checkpoint". Science (New York, N.Y.). 316: 982; author reply 98. PMID 17510348 DOI: 10.1126/science.1139523  0.513
2007 Weaver BA, Silk AD, Montagna C, Verdier-Pinard P, Cleveland DW. Aneuploidy acts both oncogenically and as a tumor suppressor. Cancer Cell. 11: 25-36. PMID 17189716 DOI: 10.1016/J.Ccr.2006.12.003  0.776
2007 Weaver BA, Cleveland DW. Does aneuploidy cause cancer? [Current Opinion in Cell Biology 2006, 18:658-667] (DOI:10.1016/j.ceb.2006.10.002) Current Opinion in Cell Biology. 19: 246. DOI: 10.1016/J.Ceb.2007.02.017  0.51
2006 Weaver BA, Cleveland DW. Does aneuploidy cause cancer? Current Opinion in Cell Biology. 18: 658-67. PMID 17046232 DOI: 10.1016/j.ceb.2006.10.002  0.596
2006 Weaver BA, Silk AD, Cleveland DW. Cell biology: nondisjunction, aneuploidy and tetraploidy. Nature. 442: E9-10; discussion E1. PMID 16915240 DOI: 10.1038/Nature05139  0.754
2005 Kops GJ, Weaver BA, Cleveland DW. On the road to cancer: aneuploidy and the mitotic checkpoint. Nature Reviews. Cancer. 5: 773-85. PMID 16195750 DOI: 10.1038/nrc1714  0.615
2005 Weaver BA, Cleveland DW. Decoding the links between mitosis, cancer, and chemotherapy: The mitotic checkpoint, adaptation, and cell death. Cancer Cell. 8: 7-12. PMID 16023594 DOI: 10.1016/j.ccr.2005.06.011  0.588
2005 Kops GJ, Kim Y, Weaver BA, Mao Y, McLeod I, Yates JR, Tagaya M, Cleveland DW. ZW10 links mitotic checkpoint signaling to the structural kinetochore. The Journal of Cell Biology. 169: 49-60. PMID 15824131 DOI: 10.1083/Jcb.200411118  0.713
2003 Weaver BA, Bonday ZQ, Putkey FR, Kops GJ, Silk AD, Cleveland DW. Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss. The Journal of Cell Biology. 162: 551-63. PMID 12925705 DOI: 10.1083/Jcb.200303167  0.611
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