Christopher J. Pittenger - Publications

Affiliations: 
Yale University, New Haven, CT 
Area:
plasticity; basal ganglia; OCD; habit
Website:
http://info.med.yale.edu/psych/faculty/pittenger.htm

117 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Pittenger C, Jiang C, DiLeone R, Duman R. The endogenous opioid system in the medial prefrontal cortex mediates ketamine's antidepressant-like actions. Research Square. PMID 37886526 DOI: 10.21203/rs.3.rs-3190391/v1  0.626
2023 Vreeland A, Calaprice D, Or-Geva N, Frye RE, Agalliu D, Lachman HM, Pittenger C, Pallanti S, Williams K, Ma M, Thienemann M, Gagliano A, Mellins E, Frankovich J. Post-infectious inflammation, autoimmunity, and OCD: Sydenham Chorea, Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal infection (PANDAS), and Pediatric Acute-onset Neuropsychiatric Disorder (PANS). Developmental Neuroscience. PMID 37742615 DOI: 10.1159/000534261  0.619
2023 Banasr M, Codeluppi S, Xu M, Bansal Y, Lepack A, Duric V, Chow M, Muir J, Bagot R, Licznerski P, Wilber S, Sanacora G, Sibille E, Duman R, Pittenger C. Prefrontal Cortex Astroglia Modulate Anhedonia-like Behavior. Research Square. PMID 37461693 DOI: 10.21203/rs.3.rs-3093428/v1  0.61
2021 Ali F, Gerhard DM, Sweasy K, Pothula S, Pittenger C, Duman RS, Kwan AC. Author Correction: Ketamine disinhibits dendrites and enhances calcium signals in prefrontal dendritic spines. Nature Communications. 12: 370. PMID 33420087 DOI: 10.1038/s41467-020-20634-x  0.373
2020 Xu J, Liu RJ, Fahey S, Frick L, Leckman J, Vaccarino F, Duman RS, Williams K, Swedo S, Pittenger C. Antibodies From Children With PANDAS Bind Specifically to Striatal Cholinergic Interneurons and Alter Their Activity. The American Journal of Psychiatry. appiajp202019070698. PMID 32539528 DOI: 10.1176/Appi.Ajp.2020.19070698  0.768
2020 Ali F, Shao LX, Gerhard DM, Sweasy K, Pothula S, Pittenger C, Duman RS, Kwan AC. Inhibitory regulation of calcium transients in prefrontal dendritic spines is compromise by a nonsense Shank3 mutation. Molecular Psychiatry. PMID 32161363 DOI: 10.1038/S41380-020-0708-6  0.511
2020 van den Heuvel OA, Boedhoe PSW, Bertolin S, Bruin WB, Francks C, Ivanov I, Jahanshad N, Kong XZ, Kwon JS, O'Neill J, Paus T, Patel Y, Piras F, Schmaal L, Soriano-Mas C, ... ... Pittenger C, et al. An overview of the first 5 years of the ENIGMA obsessive-compulsive disorder working group: The power of worldwide collaboration. Human Brain Mapping. PMID 32154629 DOI: 10.1002/Hbm.24972  0.361
2020 Ali F, Gerhard DM, Sweasy K, Pothula S, Pittenger C, Duman RS, Kwan AC. Ketamine disinhibits dendrites and enhances calcium signals in prefrontal dendritic spines. Nature Communications. 11: 72. PMID 31911591 DOI: 10.1038/S41467-019-13809-8  0.496
2020 Pittenger C. The histidine decarboxylase model of tic pathophysiology: a new focus on the histamine H 3 receptor British Journal of Pharmacology. 177: 570-579. PMID 30714121 DOI: 10.1111/Bph.14606  0.316
2020 Pushkarskaya H, Stern E, Tolin DF, Pittenger C. Excessive acquisition of information during simple judgments in individuals with hoarding disorder Journal of Obsessive-Compulsive and Related Disorders. 24: 100505. DOI: 10.1016/J.Jocrd.2020.100505  0.328
2019 Pittenger C, Pushkarskaya H, Gruner P. Animal models of OCD-relevant processes: an RDoC perspective. Journal of Obsessive-Compulsive and Related Disorders. 23. PMID 32322462 DOI: 10.1016/J.Jocrd.2019.03.001  0.323
2019 Maloney G, Koh G, Roberts S, Pittenger C. Imagery rescripting as an adjunct clinical intervention for obsessive compulsive disorder. Journal of Anxiety Disorders. 66: 102110. PMID 31357037 DOI: 10.1016/j.janxdis.2019.102110  0.348
2019 Groman SM, Keistler C, Keip AJ, Hammarlund E, DiLeone RJ, Pittenger C, Lee D, Taylor JR. Orbitofrontal Circuits Control Multiple Reinforcement-Learning Processes. Neuron. PMID 31253468 DOI: 10.1016/J.Neuron.2019.05.042  0.655
2019 Kong XZ, Boedhoe PSW, Abe Y, Alonso P, Ameis SH, Arnold PD, Assogna F, Baker JT, Batistuzzo MC, Benedetti F, Beucke JC, Bollettini I, Bose A, Brem S, Brennan BP, ... ... Pittenger C, et al. Mapping Cortical and Subcortical Asymmetry in Obsessive-Compulsive Disorder: Findings From the ENIGMA Consortium. Biological Psychiatry. PMID 31178097 DOI: 10.1016/J.Biopsych.2019.04.022  0.357
2019 Katrancha SM, Shaw JE, Zhao AY, Myers SA, Cocco AR, Jeng AT, Zhu M, Pittenger C, Greer CA, Carr SA, Xiao X, Koleske AJ. Trio Haploinsufficiency Causes Neurodevelopmental Disease-Associated Deficits. Cell Reports. 26: 2805-2817.e9. PMID 30840899 DOI: 10.1016/j.celrep.2019.02.022  0.383
2019 Pushkarskaya H, Sobowale K, Henick D, Tolin DF, Anticevic A, Pearlson GD, Levy I, Harpaz-Rotem I, Pittenger C. Contrasting contributions of anhedonia to obsessive-compulsive, hoarding, and post-traumatic stress disorders. Journal of Psychiatric Research. 109: 202-213. PMID 30572276 DOI: 10.1016/J.Jpsychires.2018.11.029  0.369
2019 Gruner P, Koller W, Anticevic A, Pittenger C. F16. Aberrant Causal Reasoning in Obsessive-Compulsive Disorder (OCD) Biological Psychiatry. 85: S219. DOI: 10.1016/J.Biopsych.2019.03.553  0.324
2018 Rapanelli M, Frick L, Jindachomthong K, Xu J, Ohtsu H, Nairn A, Pittenger C. Striatal signaling regulated by the H3R histamine receptor in a mouse model of tic pathophysiology. Neuroscience. PMID 30278251 DOI: 10.1016/j.neuroscience.2018.09.035  0.313
2018 Pittenger C, Taylor JR. Distinct but Synergistic Roles for Histone Deacetylase in the Dorsal Striatum During Habit Formation. Biological Psychiatry. 84: 322-323. PMID 30115242 DOI: 10.1016/j.biopsych.2018.06.020  0.467
2018 Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R, Patsopoulos NA, Ripke S, Wei Z, Yu D, ... ... Pittenger C, et al. Analysis of shared heritability in common disorders of the brain. Science (New York, N.Y.). 360. PMID 29930110 DOI: 10.1126/Science.Aap8757  0.383
2018 Brooks H, Kichuk SA, Adams TG, Koller WN, Eken HN, Rance M, Monahan S, Wasylink S, Kelmendi B, Pittenger C, Gruner P, Hampson M. Developing image sets for inducing obsessive-compulsive checking symptoms. Psychiatry Research. 265: 249-255. PMID 29763844 DOI: 10.1016/J.Psychres.2018.04.035  0.31
2018 Rance M, Walsh C, Sukhodolsky DG, Pittman B, Qiu M, Kichuk SA, Wasylink S, Koller WN, Bloch M, Gruner P, Scheinost D, Pittenger C, Hampson M. Time course of clinical change following neurofeedback. Neuroimage. PMID 29729393 DOI: 10.1016/J.Neuroimage.2018.05.001  0.522
2018 Fernandez TV, Leckman JF, Pittenger C. Genetic susceptibility in obsessive-compulsive disorder. Handbook of Clinical Neurology. 148: 767-781. PMID 29478613 DOI: 10.1016/B978-0-444-64076-5.00049-1  0.36
2018 Fernandez TV, State MW, Pittenger C. Tourette disorder and other tic disorders. Handbook of Clinical Neurology. 147: 343-354. PMID 29325623 DOI: 10.1016/B978-0-444-63233-3.00023-3  0.378
2018 Adkinson B, Kolobaric A, Flynn M, Dowiak C, Schleifer C, Santamauro N, Beech C, Lobe J, Zalevsky O, Cho Y, Pittenger C, Anticevic A. T18. Characterizing Reward Responsiveness in Obsessive-Compulsive Disorder and Schizophrenia Through a Probabilistic Reward Task Biological Psychiatry. 83: S135. DOI: 10.1016/J.Biopsych.2018.02.354  0.304
2017 Frick L, Rapanelli M, Jindachomthong K, Grant P, Leckman JF, Swedo S, Williams K, Pittenger C. Differential binding of antibodies in PANDAS patients to cholinergic interneurons in the striatum. Brain, Behavior, and Immunity. PMID 29233751 DOI: 10.1016/J.Bbi.2017.12.004  0.626
2017 Pushkarskaya H, Tolin D, Ruderman L, Henick D, Kelly JM, Pittenger C, Levy I. Value-based decision making under uncertainty in hoarding and obsessive- compulsive disorders. Psychiatry Research. PMID 28864119 DOI: 10.1016/j.psychres.2017.08.058  0.306
2017 Costa DLC, Diniz JB, Requena G, Joaquim MA, Pittenger C, Bloch MH, Miguel EC, Shavitt RG. Randomized, Double-Blind, Placebo-Controlled Trial of N-Acetylcysteine Augmentation for Treatment-Resistant Obsessive-Compulsive Disorder. The Journal of Clinical Psychiatry. PMID 28617566 DOI: 10.4088/Jcp.16M11101  0.565
2017 Rapanelli M, Frick L, Bito H, Pittenger C. Histamine modulation of the basal ganglia circuitry in the development of pathological grooming. Proceedings of the National Academy of Sciences of the United States of America. PMID 28584117 DOI: 10.1073/Pnas.1704547114  0.35
2017 Rapanelli M, Frick LR, Pittenger C. The Role of Interneurons in Autism and Tourette Syndrome. Trends in Neurosciences. 40: 397-407. PMID 28578790 DOI: 10.1016/J.Tins.2017.05.004  0.371
2017 Esterlis I, DellaGioia N, Pietrzak RH, Matuskey D, Nabulsi N, Abdallah CG, Yang J, Pittenger C, Sanacora G, Krystal JH, Parsey RV, Carson RE, DeLorenzo C. Ketamine-induced reduction in mGluR5 availability is associated with an antidepressant response: an [(11)C]ABP688 and PET imaging study in depression. Molecular Psychiatry. PMID 28397841 DOI: 10.1038/Mp.2017.58  0.547
2017 Rapanelli M, Frick LR, Xu M, Groman SM, Jindachomthong K, Tamamaki N, Tanahira C, Taylor JR, Pittenger C. Targeted Interneuron Depletion in the Dorsal Striatum Produces Autism-like Behavioral Abnormalities in Male but Not Female Mice. Biological Psychiatry. PMID 28347488 DOI: 10.1016/j.biopsych.2017.01.020  0.571
2017 Keistler CR, Hammarlund E, Barker JM, Bond CW, DiLeone RJ, Pittenger C, Taylor JR. Regulation of alcohol extinction and cue-induced reinstatement by specific projections between medial prefrontal cortex, nucleus accumbens and basolateral amygdala. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28336571 DOI: 10.1523/Jneurosci.3383-16.2017  0.65
2017 Pittenger C. Histidine Decarboxylase Knockout Mice as a Model of the Pathophysiology of Tourette Syndrome and Related Conditions. Handbook of Experimental Pharmacology. 241: 189-215. PMID 28233179 DOI: 10.1007/164_2016_127  0.314
2017 Adams TG, Bloch MH, Pittenger C. Intranasal Ketamine and Cognitive-Behavioral Therapy for Treatment-Refractory Obsessive-Compulsive Disorder. Journal of Clinical Psychopharmacology. PMID 28121735 DOI: 10.1097/Jcp.0000000000000659  0.558
2017 Rapanelli M, Frick L, Pogorelov V, Ohtsu H, Bito H, Pittenger C. Histamine H3R receptor activation in the dorsal striatum triggers stereotypies in a mouse model of tic disorders. Translational Psychiatry. 7: e1013. PMID 28117842 DOI: 10.1038/Tp.2016.290  0.384
2016 Frick L, Pittenger C. Microglial Dysregulation in OCD, Tourette Syndrome, and PANDAS. Clinical & Developmental Immunology. 2016: 8606057-8606057. PMID 28053994 DOI: 10.1155/2016/8606057  0.365
2016 Boedhoe PS, Schmaal L, Abe Y, Ameis SH, Arnold PD, Batistuzzo MC, Benedetti F, Beucke JC, Bollettini I, Bose A, Brem S, Calvo A, Cheng Y, Cho KI, Dallaspezia S, ... ... Pittenger C, et al. Distinct Subcortical Volume Alterations in Pediatric and Adult OCD: A Worldwide Meta- and Mega-Analysis. The American Journal of Psychiatry. appiajp201616020201. PMID 27609241 DOI: 10.1176/Appi.Ajp.2016.16020201  0.331
2016 Gruner P, Pittenger C. Cognitive inflexibility in Obsessive-Compulsive Disorder. Neuroscience. PMID 27491478 DOI: 10.1016/J.Neuroscience.2016.07.030  0.315
2016 Frick L, Rapanelli M, Abbasi E, Ohtsu H, Pittenger C. Histamine regulation of microglia: Gene-environment interaction in the regulation of central nervous system inflammation Brain Behavior and Immunity. 57: 326-337. PMID 27381299 DOI: 10.1016/J.Bbi.2016.07.002  0.302
2016 Issaria Y, Jakubovski E, Bartley CA, Pittenger C, Bloch MH. Early onset of response with selective serotonin reuptake inhibitors in obsessive-compulsive disorder: a meta-analysis. The Journal of Clinical Psychiatry. 77: e605-11. PMID 27249090 DOI: 10.4088/Jcp.14R09758  0.578
2016 Kelmendi B, Adams T, Jakubovski E, Hawkins KA, Coric V, Pittenger C. Probing Implicit Learning in Obsessive-Compulsive Disorder: Moderating Role of Medication on the Weather Prediction Task. Journal of Obsessive-Compulsive and Related Disorders. 9: 90-95. PMID 27134820 DOI: 10.1016/j.jocrd.2016.03.003  0.314
2016 Xu M, Li L, Pittenger C. Ablation of fast-spiking interneurons in the dorsal striatum, recapitulating abnormalities seen post-mortem in Tourette syndrome, produces anxiety and elevated grooming. Neuroscience. PMID 26968763 DOI: 10.1016/j.neuroscience.2016.02.074  0.384
2016 Pittenger C, Adams TG, Gallezot JD, Crowley MJ, Nabulsi N, James Ropchan, Gao H, Kichuk SA, Simpson R, Billingslea E, Hannestad J, Bloch M, Mayes L, Bhagwagar Z, Carson RE. OCD is associated with an altered association between sensorimotor gating and cortical and subcortical 5-HT1b receptor binding. Journal of Affective Disorders. 196: 87-96. PMID 26919057 DOI: 10.1016/J.Jad.2016.02.021  0.553
2016 Rapanelli M, Pittenger C. Histamine and histamine receptors in Tourette syndrome and other neuropsychiatric conditions Neuropharmacology. 106: 85-90. PMID 26282120 DOI: 10.1016/J.Neuropharm.2015.08.019  0.382
2016 Pittenger C. 37.5 Pathophysiologically Grounded Models Of Tic Disorders: Histamine Dysregulation In Tourette'S Disorder Journal of the American Academy of Child and Adolescent Psychiatry. 55. DOI: 10.1016/J.Jaac.2016.07.338  0.36
2015 Pushkarskaya H, Tolin D, Ruderman L, Kirshenbaum A, Kelly JM, Pittenger C, Levy I. Decision-making under uncertainty in obsessive-compulsive disorder. Journal of Psychiatric Research. 69: 166-73. PMID 26343609 DOI: 10.1016/J.Jpsychires.2015.08.011  0.308
2015 Pittenger C. Glutamatergic agents for OCD and related disorders Current Treatment Options in Psychiatry. 2: 271-283. PMID 26301176 DOI: 10.1007/S40501-015-0051-8  0.371
2015 Pittenger C. Glutamate modulators in the treatment of obsessive-compulsive disorder. Psychiatric Annals. 45: 308-315. PMID 26236057 DOI: 10.3928/00485713-20150602-06  0.397
2015 Pittenger C, Bloch MH, Wasylink S, Billingslea E, Simpson R, Jakubovski E, Kelmendi B, Sanacora G, Coric V. Riluzole augmentation in treatment-refractory obsessive-compulsive disorder: a pilot randomized placebo-controlled trial. The Journal of Clinical Psychiatry. 76: 1075-84. PMID 26214725 DOI: 10.4088/Jcp.14M09123  0.688
2015 Van Schalkwyk GI, Bhalla IP, Griepp M, Kelmendi B, Davidson L, Pittenger C. Toward understanding the heterogeneity in obsessive-compulsive disorder: Evidence from narratives in adult patients. The Australian and New Zealand Journal of Psychiatry. PMID 25855685 DOI: 10.1177/0004867415579919  0.378
2015 Xu M, Li L, Ohtsu H, Pittenger C. Histidine decarboxylase knockout mice, a genetic model of Tourette syndrome, show repetitive grooming after induced fear. Neuroscience Letters. 595: 50-3. PMID 25841792 DOI: 10.1016/j.neulet.2015.03.067  0.335
2015 Gruner P, Anticevic A, Lee D, Pittenger C. Arbitration between Action Strategies in Obsessive-Compulsive Disorder. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. PMID 25605642 DOI: 10.1177/1073858414568317  0.325
2015 Xu M, Kobets A, Du JC, Lennington J, Li L, Banasr M, Duman RS, Vaccarino FM, DiLeone RJ, Pittenger C. Targeted ablation of cholinergic interneurons in the dorsolateral striatum produces behavioral manifestations of Tourette syndrome. Proceedings of the National Academy of Sciences of the United States of America. 112: 893-8. PMID 25561540 DOI: 10.1073/Pnas.1419533112  0.778
2015 Fernandez TV, King RA, Pittenger C. Tourette's syndrome and translational clinical science. Journal of the American Academy of Child and Adolescent Psychiatry. 54: 6-8. PMID 25524784 DOI: 10.1016/j.jaac.2014.11.004  0.322
2015 Yu D, Mathews CA, Scharf JM, Neale BM, Davis LK, Gamazon ER, Derks EM, Evans P, Edlund CK, Crane J, Fagerness JA, Osiecki L, Gallagher P, Gerber G, Haddad S, ... ... Pittenger C, et al. Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD. The American Journal of Psychiatry. 172: 82-93. PMID 25158072 DOI: 10.1176/Appi.Ajp.2014.13101306  0.573
2014 Rapanelli M, Frick LR, Pogorelov V, Ota KT, Abbasi E, Ohtsu H, Pittenger C. Dysregulated intracellular signaling in the striatum in a pathophysiologically grounded model of Tourette syndrome. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 24: 1896-906. PMID 25464894 DOI: 10.1016/J.Euroneuro.2014.10.007  0.368
2014 Scheinost D, Stoica T, Wasylink S, Gruner P, Saksa J, Pittenger C, Hampson M. Resting state functional connectivity predicts neurofeedback response. Frontiers in Behavioral Neuroscience. 8: 338. PMID 25309375 DOI: 10.3389/Fnbeh.2014.00338  0.342
2014 Pittenger C, Bloch MH. Pharmacological treatment of obsessive-compulsive disorder. The Psychiatric Clinics of North America. 37: 375-91. PMID 25150568 DOI: 10.1016/J.Psc.2014.05.006  0.584
2014 McGrath LM, Yu D, Marshall C, Davis LK, Thiruvahindrapuram B, Li B, Cappi C, Gerber G, Wolf A, Schroeder FA, Osiecki L, O'Dushlaine C, Kirby A, Illmann C, Haddad S, ... ... Pittenger C, et al. Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study. Journal of the American Academy of Child and Adolescent Psychiatry. 53: 910-9. PMID 25062598 DOI: 10.1016/J.Jaac.2014.04.022  0.575
2014 Bloch MH, Bartley CA, Zipperer L, Jakubovski E, Landeros-Weisenberger A, Pittenger C, Leckman JF. Meta-analysis: hoarding symptoms associated with poor treatment outcome in obsessive-compulsive disorder. Molecular Psychiatry. 19: 1025-30. PMID 24912494 DOI: 10.1038/Mp.2014.50  0.579
2014 Lee AS, André JM, Pittenger C. Lesions of the dorsomedial striatum delay spatial learning and render cue-based navigation inflexible in a water maze task in mice. Frontiers in Behavioral Neuroscience. 8: 42. PMID 24592223 DOI: 10.3389/Fnbeh.2014.00042  0.414
2014 Castellan Baldan L, Williams KA, Gallezot JD, Pogorelov V, Rapanelli M, Crowley M, Anderson GM, Loring E, Gorczyca R, Billingslea E, Wasylink S, Panza KE, Ercan-Sencicek AG, Krusong K, Leventhal BL, ... ... Pittenger C, et al. Histidine decarboxylase deficiency causes tourette syndrome: parallel findings in humans and mice. Neuron. 81: 77-90. PMID 24411733 DOI: 10.1016/J.Neuron.2013.10.052  0.673
2014 Anticevic A, Hu S, Zhang S, Savic A, Billingslea E, Wasylink S, Repovs G, Cole MW, Bednarski S, Krystal JH, Bloch MH, Li CS, Pittenger C. Global resting-state functional magnetic resonance imaging analysis identifies frontal cortex, striatal, and cerebellar dysconnectivity in obsessive-compulsive disorder. Biological Psychiatry. 75: 595-605. PMID 24314349 DOI: 10.1016/J.Biopsych.2013.10.021  0.556
2013 Davis LK, Yu D, Keenan CL, Gamazon ER, Konkashbaev AI, Derks EM, Neale BM, Yang J, Lee SH, Evans P, Barr CL, Bellodi L, Benarroch F, Berrio GB, Bienvenu OJ, ... ... Pittenger C, et al. Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture. Plos Genetics. 9: e1003864. PMID 24204291 DOI: 10.1371/Journal.Pgen.1003864  0.553
2013 Frick LR, Williams K, Pittenger C. Microglial dysregulation in psychiatric disease. Clinical & Developmental Immunology. 2013: 608654. PMID 23690824 DOI: 10.1155/2013/608654  0.62
2013 Niciu MJ, Grunschel BD, Corlett PR, Pittenger C, Bloch MH. Two cases of delayed-onset suicidal ideation, dysphoria and anxiety after ketamine infusion in patients with obsessive-compulsive disorder and a history of major depressive disorder. Journal of Psychopharmacology (Oxford, England). 27: 651-4. PMID 23676198 DOI: 10.1177/0269881113486718  0.579
2013 Bloch MH, Green C, Kichuk SA, Dombrowski PA, Wasylink S, Billingslea E, Landeros-Weisenberger A, Kelmendi B, Goodman WK, Leckman JF, Coric V, Pittenger C. Long-term outcome in adults with obsessive-compulsive disorder. Depression and Anxiety. 30: 716-22. PMID 23532944 DOI: 10.1002/da.22103  0.512
2013 Panza KE, Pittenger C, Bloch MH. Age and gender correlates of pulling in pediatric trichotillomania. Journal of the American Academy of Child and Adolescent Psychiatry. 52: 241-9. PMID 23452681 DOI: 10.1016/J.Jaac.2012.12.019  0.536
2013 Bloch MH, Panza KE, Grant JE, Pittenger C, Leckman JF. N-Acetylcysteine in the treatment of pediatric trichotillomania: a randomized, double-blind, placebo-controlled add-on trial. Journal of the American Academy of Child and Adolescent Psychiatry. 52: 231-40. PMID 23452680 DOI: 10.1016/J.Jaac.2012.12.020  0.535
2013 Kichuk SA, Torres AR, Fontenelle LF, Rosário MC, Shavitt RG, Miguel EC, Pittenger C, Bloch MH. Symptom dimensions are associated with age of onset and clinical course of obsessive-compulsive disorder. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 44: 233-9. PMID 23410525 DOI: 10.1016/J.Pnpbp.2013.02.003  0.536
2013 Quinn JJ, Pittenger C, Lee AS, Pierson JL, Taylor JR. Striatum-dependent habits are insensitive to both increases and decreases in reinforcer value in mice. The European Journal of Neuroscience. 37: 1012-21. PMID 23298231 DOI: 10.1111/Ejn.12106  0.596
2013 Stewart SE, Yu D, Scharf JM, Neale BM, Fagerness JA, Mathews CA, Arnold PD, Evans PD, Gamazon ER, Davis LK, Osiecki L, McGrath L, Haddad S, Crane J, Hezel D, ... ... Pittenger C, et al. Genome-wide association study of obsessive-compulsive disorder. Molecular Psychiatry. 18: 788-98. PMID 22889921 DOI: 10.1038/Mp.2012.85  0.525
2013 Stewart SE, Yu D, Scharf JM, Neale BM, Fagerness JA, Mathews CA, Arnold PD, Evans PD, Gamazon ER, Osiecki L, McGrath L, Haddad S, Crane J, Hezel D, Illman C, ... ... Pittenger C, et al. Erratum: Genome-wide association study of obsessive-compulsive disorder Molecular Psychiatry. 18: 843-843. DOI: 10.1038/Mp.2013.15  0.518
2012 Bloch MH, Wasylink S, Landeros-Weisenberger A, Panza KE, Billingslea E, Leckman JF, Krystal JH, Bhagwagar Z, Sanacora G, Pittenger C. Effects of ketamine in treatment-refractory obsessive-compulsive disorder. Biological Psychiatry. 72: 964-70. PMID 22784486 DOI: 10.1016/J.Biopsych.2012.05.028  0.669
2012 Carty NC, Xu J, Kurup P, Brouillette J, Goebel-Goody SM, Austin DR, Yuan P, Chen G, Correa PR, Haroutunian V, Pittenger C, Lombroso PJ. The tyrosine phosphatase STEP: implications in schizophrenia and the molecular mechanism underlying antipsychotic medications. Translational Psychiatry. 2: e137. PMID 22781170 DOI: 10.1038/Tp.2012.63  0.327
2012 Hampson M, Stoica T, Saksa J, Scheinost D, Qiu M, Bhawnani J, Pittenger C, Papademetris X, Constable T. Real-time fMRI biofeedback targeting the orbitofrontal cortex for contamination anxiety. Journal of Visualized Experiments : Jove. PMID 22297729 DOI: 10.3791/3535  0.35
2011 Pittenger C. Pathophysiological Modeling of Obsessive-Compulsive Disorder: Challenges, and Progress Biological Psychiatry. 70: 1002-1003. PMID 22045035 DOI: 10.1016/J.Biopsych.2011.10.005  0.364
2011 Pittenger C, Bloch MH, Williams K. Glutamate abnormalities in obsessive compulsive disorder: neurobiology, pathophysiology, and treatment. Pharmacology & Therapeutics. 132: 314-32. PMID 21963369 DOI: 10.1016/J.Pharmthera.2011.09.006  0.725
2011 Jakubovski E, Pittenger C, Torres AR, Fontenelle LF, do Rosario MC, Ferrão YA, de Mathis MA, Miguel EC, Bloch MH. Dimensional correlates of poor insight in obsessive-compulsive disorder. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 35: 1677-81. PMID 21640153 DOI: 10.1016/J.Pnpbp.2011.05.012  0.594
2011 Kelmendi B, Holsbach-Beltrame M, McIntosh AM, Hilt L, George ED, Kitchen RR, Carlyle BC, Pittenger C, Coric V, Nolen-Hoeksema S, Sanacora G, Simen AA. Association of polymorphisms in HCN4 with mood disorders and obsessive compulsive disorder. Neuroscience Letters. 496: 195-9. PMID 21529705 DOI: 10.1016/J.Neulet.2011.04.026  0.574
2011 Bloch M, State M, Pittenger C. Recent advances in Tourette syndrome Current Opinion in Neurology. 24: 119-125. PMID 21386676 DOI: 10.1097/Wco.0B013E328344648C  0.561
2011 Ramsey LCB, Xu M, Wood N, Pittenger C. Lesions of the dorsomedial striatum disrupt prepulse inhibition. Neuroscience. 180: 222-228. PMID 21315809 DOI: 10.1016/J.Neuroscience.2011.01.041  0.321
2010 Bloch MH, Pittenger C. The Genetics of Obsessive-Compulsive Disorder. Current Psychiatry Reviews. 6: 91-103. PMID 23970845 DOI: 10.2174/157340010791196439  0.589
2010 Gourley SL, Lee AS, Howell JL, Pittenger C, Taylor JR. Dissociable regulation of instrumental action within mouse prefrontal cortex. The European Journal of Neuroscience. 32: 1726-34. PMID 21044173 DOI: 10.1111/J.1460-9568.2010.07438.X  0.581
2010 Zhang Y, Kurup P, Xu J, Carty N, Fernandez SM, Nygaard HB, Pittenger C, Greengard P, Strittmatter SM, Nairn AC, Lombroso PJ. Genetic reduction of striatal-enriched tyrosine phosphatase (STEP) reverses cognitive and cellular deficits in an Alzheimer's disease mouse model. Proceedings of the National Academy of Sciences of the United States of America. 107: 19014-9. PMID 20956308 DOI: 10.1073/pnas.1013543107  0.318
2010 Landeros-Weisenberger A, Bloch MH, Kelmendi B, Wegner R, Nudel J, Dombrowski P, Pittenger C, Krystal JH, Goodman WK, Leckman JF, Coric V. Dimensional predictors of response to SRI pharmacotherapy in obsessive-compulsive disorder. Journal of Affective Disorders. 121: 175-9. PMID 19577308 DOI: 10.1016/J.Jad.2009.06.010  0.577
2010 Bloch MH, McGuire J, Landeros-Weisenberger A, Leckman JF, Pittenger C. Meta-analysis of the dose-response relationship of SSRI in obsessive-compulsive disorder. Molecular Psychiatry. 15: 850-5. PMID 19468281 DOI: 10.1038/Mp.2009.50  0.565
2009 Fasano S, Pittenger C, Brambilla R. Inhibition of CREB activity in the dorsal portion of the striatum potentiates behavioral responses to drugs of abuse. Frontiers in Behavioral Neuroscience. 3: 29. PMID 19826621 DOI: 10.3389/Neuro.08.029.2009  0.31
2008 Lee AS, Duman RS, Pittenger C. A double dissociation revealing bidirectional competition between striatum and hippocampus during learning. Proceedings of the National Academy of Sciences of the United States of America. 105: 17163-8. PMID 18955704 DOI: 10.1073/Pnas.0807749105  0.568
2008 Bloch MH, Landeros-Weisenberger A, Rosario MC, Pittenger C, Leckman JF. Meta-analysis of the symptom structure of obsessive-compulsive disorder. The American Journal of Psychiatry. 165: 1532-42. PMID 18923068 DOI: 10.1176/Appi.Ajp.2008.08020320  0.537
2008 Pittenger C, Coric V, Banasr M, Bloch M, Krystal JH, Sanacora G. Riluzole in the treatment of mood and anxiety disorders. Cns Drugs. 22: 761-86. PMID 18698875 DOI: 10.2165/00023210-200822090-00004  0.704
2008 Town T, Laouar Y, Pittenger C, Mori T, Szekely CA, Tan J, Duman RS, Flavell RA. Blocking TGF-beta-Smad2/3 innate immune signaling mitigates Alzheimer-like pathology. Nature Medicine. 14: 681-7. PMID 18516051 DOI: 10.1038/Nm1781  0.45
2008 Pittenger C, Kelmendi B, Wasylink S, Bloch MH, Coric V. Riluzole augmentation in treatment-refractory obsessive-compulsive disorder: a series of 13 cases, with long-term follow-up. Journal of Clinical Psychopharmacology. 28: 363-7. PMID 18480706 DOI: 10.1097/Jcp.0B013E3181727548  0.583
2008 Bloch MH, Landeros-Weisenberger A, Sen S, Dombrowski P, Kelmendi B, Coric V, Pittenger C, Leckman JF. Association of the serotonin transporter polymorphism and obsessive-compulsive disorder: systematic review. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 147: 850-8. PMID 18186076 DOI: 10.1002/Ajmg.B.30699  0.549
2008 Pittenger C, Duman RS. Stress, depression, and neuroplasticity: a convergence of mechanisms. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 88-109. PMID 17851537 DOI: 10.1038/sj.npp.1301574  0.503
2008 Town T, Laouar Y, Pittenger C, Mori T, Szekely CA, Tan J, Duman RS, Flavell RA. O4-02-06: Blocking Tgf-β-smad 2/3 innate immune signaling mitigates Alzheimer-like pathology in transgenic mice Alzheimer's & Dementia. 4: T187-T188. DOI: 10.1016/J.Jalz.2008.05.514  0.442
2008 Bloch MH, Landeros-Weisenberger A, Dombrowski P, Nudel J, Pittenger C, Leckman JF, Kelmendi B, Wegner R, Coric V. Response to Chamberlain et al. Re: Systematic Review: Pharmacological and Behavioral Treatments for Trichotillomania Biological Psychiatry. 63: e34-e35. DOI: 10.1016/J.Biopsych.2008.01.022  0.489
2007 Bloch MH, Landeros-Weisenberger A, Dombrowski P, Kelmendi B, Wegner R, Nudel J, Pittenger C, Leckman JF, Coric V. Systematic review: pharmacological and behavioral treatment for trichotillomania. Biological Psychiatry. 62: 839-46. PMID 17727824 DOI: 10.1016/J.Biopsych.2007.05.019  0.53
2007 Pittenger C, Sanacora G, Krystal JH. The NMDA receptor as a therapeutic target in major depressive disorder. Cns & Neurological Disorders Drug Targets. 6: 101-15. PMID 17430148 DOI: 10.2174/187152707780363267  0.559
2007 Coric V, Kelmendi B, Pittenger C, Wasylink S, Bloch MH, Green J. Beneficial effects of the antiglutamatergic agent riluzole in a patient diagnosed with trichotillomania. The Journal of Clinical Psychiatry. 68: 170-1. PMID 17284151 DOI: 10.4088/Jcp.V68N0123F  0.488
2006 Sasso DA, Kalanithi PS, Trueblood KV, Pittenger C, Kelmendi B, Wayslink S, Malison RT, Krystal JH, Coric V. Beneficial effects of the glutamate-modulating agent riluzole on disordered eating and pathological skin-picking behaviors. Journal of Clinical Psychopharmacology. 26: 685-7. PMID 17110840 DOI: 10.1097/01.Jcp.0000245567.29531.D6  0.338
2006 Pittenger C, Naungayan C, Kendell SF, Coric V, Malison R, Krystal JH, Sanacora GS. Visual hallucinations from the addition of riluzole to memantine and bupropion. Journal of Clinical Psychopharmacology. 26: 218-20. PMID 16633160 DOI: 10.1097/01.Jcp.0000203228.64117.9F  0.468
2006 Pittenger C, Fasano S, Mazzocchi-Jones D, Dunnett SB, Kandel ER, Brambilla R. Impaired bidirectional synaptic plasticity and procedural memory formation in striatum-specific cAMP response element-binding protein-deficient mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 2808-13. PMID 16525060 DOI: 10.1523/Jneurosci.5406-05.2006  0.473
2006 Pittenger C, Krystal JH, Coric V. Glutamate-modulating drugs as novel pharmacotherapeutic agents in the treatment of obsessive-compulsive disorder. Neurorx : the Journal of the American Society For Experimental Neurotherapeutics. 3: 69-81. PMID 16490414 DOI: 10.1016/J.Nurx.2005.12.006  0.394
2006 Lafleur DL, Pittenger C, Kelmendi B, Gardner T, Wasylink S, Malison RT, Sanacora G, Krystal JH, Coric V. N-acetylcysteine augmentation in serotonin reuptake inhibitor refractory obsessive-compulsive disorder. Psychopharmacology. 184: 254-6. PMID 16374600 DOI: 10.1007/S00213-005-0246-6  0.618
2005 Pittenger C, Krystal JH, Coric V. Initial evidence of the beneficial effects of glutamate-modulating agents in the treatment of self-injurious behavior associated with borderline personality disorder. The Journal of Clinical Psychiatry. 66: 1492-3. PMID 16420092 DOI: 10.4088/Jcp.V66N1121D  0.332
2005 Coric V, Taskiran S, Pittenger C, Wasylink S, Mathalon DH, Valentine G, Saksa J, Wu YT, Gueorguieva R, Sanacora G, Malison RT, Krystal JH. Riluzole augmentation in treatment-resistant obsessive-compulsive disorder: an open-label trial. Biological Psychiatry. 58: 424-8. PMID 15993857 DOI: 10.1016/J.Biopsych.2005.04.043  0.586
2005 Etkin A, Pittenger C, Polan HJ, Kandel ER. Toward a neurobiology of psychotherapy: basic science and clinical applications. The Journal of Neuropsychiatry and Clinical Neurosciences. 17: 145-58. PMID 15939967 DOI: 10.1176/Jnp.17.2.145  0.595
2004 Huang YY, Pittenger C, Kandel ER. A form of long-lasting, learning-related synaptic plasticity in the hippocampus induced by heterosynaptic low-frequency pairing. Proceedings of the National Academy of Sciences of the United States of America. 101: 859-64. PMID 14711997 DOI: 10.1073/pnas.2237201100  0.45
2003 Kandel ER, Pittenger C. [Past and future studies of memory]. Kos. 38-43. PMID 12760381  0.331
2003 Pittenger C, Kandel ER. In search of general mechanisms for long-lasting plasticity: Aplysia and the hippocampus. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 358: 757-63. PMID 12740123 DOI: 10.1098/rstb.2002.1247  0.446
2003 Barco A, Pittenger C, Kandel ER. CREB, memory enhancement and the treatment of memory disorders: promises, pitfalls and prospects. Expert Opinion On Therapeutic Targets. 7: 101-14. PMID 12556206 DOI: 10.1517/14728222.7.1.101  0.671
2002 Pittenger C, Huang YY, Paletzki RF, Bourtchouladze R, Scanlin H, Vronskaya S, Kandel ER. Reversible inhibition of CREB/ATF transcription factors in region CA1 of the dorsal hippocampus disrupts hippocampus-dependent spatial memory. Neuron. 34: 447-62. PMID 11988175 DOI: 10.1016/S0896-6273(02)00684-0  0.477
2001 Patterson SL, Pittenger C, Morozov A, Martin KC, Scanlin H, Drake C, Kandel ER. Some forms of cAMP-mediated long-lasting potentiation are associated with release of BDNF and nuclear translocation of phospho-MAP kinase. Neuron. 32: 123-40. PMID 11604144 DOI: 10.1016/S0896-6273(01)00443-3  0.745
1999 Kandel ER, Pittenger C. The past, the future and the biology of memory storage. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 354: 2027-52. PMID 10670023 DOI: 10.1098/rstb.1999.0542  0.428
1998 Pittenger C, Kandel E. A genetic switch for long-term memory. Comptes Rendus De L'Acadã©Mie Des Sciences. Sã©Rie Iii, Sciences De La Vie. 321: 91-6. PMID 9759326 DOI: 10.1016/S0764-4469(97)89807-1  0.455
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