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Laurie L. Parker - Publications

Affiliations: 
2008-2014 MCMP Purdue University, West Lafayette, IN, United States 
 2014- BMBB University of Minnesota, Twin Cities, Minneapolis, MN 
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56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Widstrom NE, Andrianov GV, Heier JL, Heier C, Karanicolas J, Parker LL. Novel Substrate Prediction for the TAM Family of RTKs Using Phosphoproteomics and Structure-Based Modeling. Acs Chemical Biology. 19: 117-128. PMID 38159292 DOI: 10.1021/acschembio.3c00549  0.477
2022 Boni C, Bonifacio M, Vezzalini M, Scaffidi L, Tomasello L, Parker LL, Boscarino D, Paladin D, Krampera M, Sorio C. Successful Preservation of Native BCR::ABL1 in Chronic Myeloid Leukemia Primary Leukocytes Reveals a Reduced Kinase Activity. Frontiers in Oncology. 12: 904510. PMID 35756686 DOI: 10.3389/fonc.2022.904510  0.425
2022 Widstrom NE, Perez M, Pratt ED, Heier JL, Blankenhorn JF, Breidenbach L, Peterson H, Parker LL. Novel Bruton's Tyrosine Kinase (BTK) Substrates for Time-Resolved Luminescence Assays. Acs Chemical Biology. 17: 1328-1333. PMID 35653784 DOI: 10.1021/acschembio.2c00106  0.792
2022 Jena S, Parker LL. Fluorescence Lifetime Imaging Probes for Cell-Based Measurements of Enzyme Activity. Methods in Molecular Biology (Clifton, N.J.). 2394: 133-162. PMID 35094326 DOI: 10.1007/978-1-0716-1811-0_9  0.429
2021 Karamafrooz A, Brennan J, Thomas DD, Parker LL. Integrated Phosphoproteomics for Identifying Substrates of Human Protein Kinase A () and Its Oncogenic Mutant 1. Journal of Proteome Research. PMID 34436901 DOI: 10.1021/acs.jproteome.1c00500  0.412
2020 Jena S, Damayanti NP, Tan J, Pratt ED, Irudayaraj JMK, Parker LL. Multiplexable fluorescence lifetime imaging (FLIM) probes for Abl and Src-family kinases. Chemical Communications (Cambridge, England). PMID 33035286 DOI: 10.1039/d0cc05030j  0.766
2019 Perez M, Blankenhorn J, Murray KJ, Parker LL. High-throughput Identification of FLT3 Wild-type and Mutant Kinase Substrate Preferences and Application to Design of Sensitive In Vitro Kinase Assay Substrates. Molecular & Cellular Proteomics : McP. 18: 477-489. PMID 33431123 DOI: 10.1074/mcp.RA118.001111  0.43
2019 Joshi MK, Burton RA, Wu H, Lipchik AM, Craddock BP, Mo H, Parker LL, Miller WT, Post CB. Substrate binding to Src: a new perspective on tyrosine kinase substrate recognition from NMR and molecular dynamics. Protein Science : a Publication of the Protein Society. PMID 31697410 DOI: 10.1002/Pro.3777  0.812
2019 Kruk M, Widstrom N, Jena S, Wolter NL, Blankenhorn JF, Abdalla I, Yang TY, Parker LL. Assays for tyrosine phosphorylation in human cells. Methods in Enzymology. 626: 375-406. PMID 31606083 DOI: 10.1016/Bs.Mie.2019.06.026  0.577
2019 Moreno NS, Liu J, Haas KM, Parker LL, Chakraborty C, Kron SJ, Hodges K, Miller LD, Langefeld C, Robinson PJ, Lelièvre SA, Vidi PA. The nuclear structural protein NuMA is a negative regulator of 53BP1 in DNA double-strand break repair. Nucleic Acids Research. PMID 31511892 DOI: 10.1093/Nar/Gkz802  0.519
2019 Salvador Moreno N, Liu J, Haas KM, Parker LL, Chakraborty C, Kron SJ, Hodges K, Miller LD, Langefeld C, Robinson PJ, Lelièvre SA, Vidi PA. The nuclear structural protein NuMA is a negative regulator of 53BP1 in DNA double-strand break repair. Nucleic Acids Research. PMID 30812030 DOI: 10.1093/Nar/Gkz138  0.541
2019 Noel BM, Ouellette SB, Marholz L, Dickey D, Navis C, Yang TY, Nguyen V, Parker SJ, Bernlohr D, Sachs Z, Parker LL. Multi-omic profiling of TKI resistant K562 cells suggests metabolic reprogramming to promote cell survival. Journal of Proteome Research. PMID 30730747 DOI: 10.1021/Acs.Jproteome.9B00028  0.331
2018 Perez M, Blankenhorn J, Murray KJ, Parker LL. High-throughput identification of FLT3 wild-type and mutant kinase substrate preferences and application to design of sensitive in vitro kinase assay substrates. Molecular & Cellular Proteomics : McP. PMID 30541869 DOI: 10.1074/Mcp.Ra118.001111  0.522
2018 Marholz LJ, Zeringo NA, Lou HJ, Turk BE, Parker LL. In Silico Design and in Vitro Characterization of Universal Tyrosine Kinase Peptide Substrates. Biochemistry. PMID 29528224 DOI: 10.1021/Acs.Biochem.8B00044  0.511
2017 Kigar SL, Chang L, Guerrero CR, Sehring JR, Cuarenta A, Parker LL, Bakshi VP, Auger AP. N6-methyladenine is an epigenetic marker of mammalian early life stress. Scientific Reports. 7: 18078. PMID 29273787 DOI: 10.1038/S41598-017-18414-7  0.721
2016 Ouellette SB, Noel BM, Parker LL. A Cell-Based Assay for Measuring Endogenous BcrAbl Kinase Activity and Inhibitor Resistance. Plos One. 11: e0161748. PMID 27598410 DOI: 10.1371/Journal.Pone.0161748  0.549
2016 Cui W, Parker LL. Modular, Antibody-free Time-Resolved LRET Kinase Assay Enabled by Quantum Dots and Tb(3+)-sensitizing Peptides. Scientific Reports. 6: 28971. PMID 27426233 DOI: 10.1038/Srep28971  0.54
2015 Wang L, Yang L, Pan L, Kadasala N, Xue L, Schuster RJ, Parker LL, Wei A, Tao WA. Time-resolved Proteomic Visualization of Dendrimer Cellular Entry and Trafficking. Journal of the American Chemical Society. PMID 26425924 DOI: 10.1021/Jacs.5B07875  0.307
2015 Lipchik AM, Perez M, Cui W, Parker LL. Multicolored, Tb³⁺-Based Antibody-Free Detection of Multiple Tyrosine Kinase Activities. Analytical Chemistry. 87: 7555-8. PMID 26207839 DOI: 10.1021/Acs.Analchem.5B02233  0.81
2015 Lipchik AM, Perez M, Bolton S, Dumrongprechachan V, Ouellette SB, Cui W, Parker LL. KINATEST-ID: a pipeline to develop phosphorylation-dependent terbium sensitizing kinase assays. Journal of the American Chemical Society. 137: 2484-94. PMID 25689372 DOI: 10.1021/Ja507164A  0.816
2015 Cui W, Parker LL. A time-resolved luminescence biosensor assay for anaplastic lymphoma kinase (ALK) activity. Chemical Communications (Cambridge, England). 51: 362-5. PMID 25406835 DOI: 10.1039/C4Cc07453J  0.57
2015 Lipchik AM, Perez M, Cui W, Parker LL. Multicolored, Tb3+-Based Antibody-Free Detection of Multiple Tyrosine Kinase Activities Analytical Chemistry. 87: 7555-7558. DOI: 10.1021/acs.analchem.5b02233  0.779
2014 Gui J, Liu B, Cao G, Lipchik AM, Perez M, Dekan Z, Mobli M, Daly NL, Alewood PF, Parker LL, King GF, Zhou Y, Jordt SE, Nitabach MN. A tarantula-venom peptide antagonizes the TRPA1 nociceptor ion channel by binding to the S1-S4 gating domain. Current Biology : Cb. 24: 473-83. PMID 24530065 DOI: 10.1016/J.Cub.2014.01.013  0.728
2013 Hu L, Yang L, Lipchik AM, Geahlen RL, Parker LL, Tao WA. A quantitative proteomics-based competition binding assay to characterize pITAM-protein interactions. Analytical Chemistry. 85: 5071-7. PMID 23611696 DOI: 10.1021/Ac400359T  0.76
2013 Damayanti NP, Parker LL, Irudayaraj JM. Fluorescence lifetime imaging of biosensor peptide phosphorylation in single live cells. Angewandte Chemie (International Ed. in English). 52: 3931-4. PMID 23450802 DOI: 10.1002/Anie.201209303  0.594
2013 Yang TY, Eissler CL, Hall MC, Parker LL. A multiple reaction monitoring (MRM) method to detect Bcr-Abl kinase activity in CML using a peptide biosensor. Plos One. 8: e56627. PMID 23437189 DOI: 10.1371/Journal.Pone.0056627  0.524
2013 Lipchik AM, Parker LL. Time-resolved luminescence detection of spleen tyrosine kinase activity through terbium sensitization. Analytical Chemistry. 85: 2582-8. PMID 23414415 DOI: 10.1021/Ac3023422  0.822
2012 Lipchik AM, Killins RL, Geahlen RL, Parker LL. A peptide-based biosensor assay to detect intracellular Syk kinase activation and inhibition. Biochemistry. 51: 7515-24. PMID 22920457 DOI: 10.1021/Bi300970H  0.814
2012 Tang J, Wang JY, Parker LL. Detection of early Abl kinase activation after ionizing radiation by using a peptide biosensor. Chembiochem : a European Journal of Chemical Biology. 13: 665-73. PMID 22334513 DOI: 10.1002/Cbic.201100763  0.535
2012 Martin VA, Wang WH, Lipchik AM, Parker LL, He Y, Zhang S, Zhang ZY, Geahlen RL. Akt2 inhibits the activation of NFAT in lymphocytes by modulating calcium release from intracellular stores. Cellular Signalling. 24: 1064-73. PMID 22261254 DOI: 10.1016/J.Cellsig.2012.01.001  0.753
2012 Bremmer SC, Hall H, Martinez JS, Eissler CL, Hinrichsen TH, Rossie S, Parker LL, Hall MC, Charbonneau H. Cdc14 phosphatases preferentially dephosphorylate a subset of cyclin-dependent kinase (Cdk) sites containing phosphoserine. The Journal of Biological Chemistry. 287: 1662-9. PMID 22117071 DOI: 10.1074/Jbc.M111.281105  0.488
2012 Lipchik AM, Parker LL. Abstract A18: Time-resolved luminescence detection of spleen tyrosine kinase activity through terbium sensitization Cancer Research. 72. DOI: 10.1158/1538-7445.Csb12-A18  0.821
2011 Eissler CL, Bremmer SC, Martinez JS, Parker LL, Charbonneau H, Hall MC. A general strategy for studying multisite protein phosphorylation using label-free selected reaction monitoring mass spectrometry. Analytical Biochemistry. 418: 267-75. PMID 21810403 DOI: 10.1016/J.Ab.2011.07.015  0.509
2011 Tang J, Wang JY, Parker L. Abstract 2479: Detecting Abelson tyrosine kinase activation by ATM and DNA-PK after exposure to ionizing radiation using a peptide biosensor Cancer Research. 71: 2479-2479. DOI: 10.1158/1538-7445.Am2011-2479  0.549
2010 Wu D, Sylvester JE, Parker LL, Zhou G, Kron SJ. Peptide reporters of kinase activity in whole cell lysates. Biopolymers. 94: 475-86. PMID 20593469 DOI: 10.1002/Bip.21401  0.805
2010 Placzek EA, Plebanek MP, Lipchik AM, Kidd SR, Parker LL. A peptide biosensor for detecting intracellular Abl kinase activity using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Analytical Biochemistry. 397: 73-8. PMID 19818327 DOI: 10.1016/J.Ab.2009.09.048  0.817
2008 Parker LL, Kron SJ. Kinase activation in circulating cells: opportunities for biomarkers for diagnosis and therapeutic monitoring. Expert Opinion On Medical Diagnostics. 2: 33-46. PMID 23485115 DOI: 10.1517/17530059.2.1.33  0.683
2008 Wu D, Mand MR, Veach DR, Parker LL, Clarkson B, Kron SJ. A solid-phase Bcr-Abl kinase assay in 96-well hydrogel plates. Analytical Biochemistry. 375: 18-26. PMID 18194660 DOI: 10.1016/J.Ab.2007.12.023  0.729
2008 Parker L, Engel-Hall A, Drew K, Steinhardt G, Helseth DL, Jabon D, McMurry T, Angulo DS, Kron SJ. Investigating quantitation of phosphorylation using MALDI-TOF mass spectrometry. Journal of Mass Spectrometry : Jms. 43: 518-27. PMID 18064576 DOI: 10.1002/Jms.1342  0.641
2006 Parker LL, Brueggemeier SB, Rhee WJ, Wu D, Kent SB, Kron SJ, Palecek SP. Photocleavable peptide hydrogel arrays for MALDI-TOF analysis of kinase activity. The Analyst. 131: 1097-104. PMID 17003856 DOI: 10.1039/B607180E  0.747
2006 Parker LL, Kurutz JW, Kent SB, Kron SJ. Control of the yeast cell cycle with a photocleavable alpha-factor analogue. Angewandte Chemie (International Ed. in English). 45: 6322-5. PMID 16937420 DOI: 10.1002/Anie.200602439  0.685
2005 Wu D, Nair-Gill E, Sher DA, Parker LL, Campbell JM, Siddiqui M, Stock W, Kron SJ. Assaying Bcr-Abl kinase activity and inhibition in whole cell extracts by phosphorylation of substrates immobilized on agarose beads. Analytical Biochemistry. 347: 67-76. PMID 16236241 DOI: 10.1016/J.Ab.2005.09.001  0.725
2005 Parker LL, Schilling AB, Kron SJ, Kent SB. Optimizing thiophosphorylation in the presence of competing phosphorylation with MALDI-TOF-MS detection. Journal of Proteome Research. 4: 1863-6. PMID 16212443 DOI: 10.1021/Pr050150E  0.728
2005 Parker LL, Anderson FM, O'Hare CC, Lacy SM, Bingham JP, Robins DJ, Hartley JA. Synthesis of novel DNA cross-linking antitumour agents based on polyazamacrocycles. Bioorganic & Medicinal Chemistry. 13: 2389-95. PMID 15755641 DOI: 10.1016/J.Bmc.2005.01.055  0.526
2004 Parker LL, Lacy SM, Farrugia LJ, Evans C, Robins DJ, O'Hare CC, Hartley JA, Jaffar M, Stratford IJ. A novel design strategy for stable metal complexes of nitrogen mustards as bioreductive prodrugs. Journal of Medicinal Chemistry. 47: 5683-9. PMID 15509167 DOI: 10.1021/Jm049866W  0.533
2003 Parker LL, Gowans ND, Jones SW, Robins DJ. A practical method for building linear and cyclic triamines from (2-trimethylsilyl)ethanesulfonamides (SES-amides) Tetrahedron. 59: 10165-10171. DOI: 10.1016/J.Tet.2003.10.067  0.517
2000 Liu M, Parker LL, Wadzinski BE, Shieh BH. Reversible phosphorylation of the signal transduction complex in Drosophila photoreceptors. The Journal of Biological Chemistry. 275: 12194-9. PMID 10766855 DOI: 10.1074/Jbc.275.16.12194  0.329
1995 Parker LL, Sylvestre PJ, Byrnes MJ, Liu F, Piwnica-Worms H. Identification of a 95-kDa WEE1-like tyrosine kinase in HeLa cells. Proceedings of the National Academy of Sciences of the United States of America. 92: 9638-42. PMID 7568188 DOI: 10.1073/Pnas.92.21.9638  0.346
1993 Parker LL, Walter SA, Young PG, Piwnica-Worms H. Phosphorylation and inactivation of the mitotic inhibitor Wee1 by the nim1/cdr1 kinase. Nature. 363: 736-8. PMID 8515817 DOI: 10.1038/363736A0  0.452
1993 Peeper DS, Parker LL, Ewen ME, Toebes M, Hall FL, Xu M, Zantema A, van der Eb AJ, Piwnica-Worms H. A- and B-type cyclins differentially modulate substrate specificity of cyclin-cdk complexes. The Embo Journal. 12: 1947-54. PMID 8491188  0.318
1993 Atherton-Fessler S, Parker LL, Geahlen RL, Piwnica-Worms H. Mechanisms of p34cdc2 regulation. Molecular and Cellular Biology. 13: 1675-85. PMID 8441405 DOI: 10.1128/Mcb.13.3.1675  0.386
1992 Parker LL, Piwnica-Worms H. Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase. Science (New York, N.Y.). 257: 1955-7. PMID 1384126 DOI: 10.1126/Science.1384126  0.401
1992 Parker LL, Atherton-Fessler S, Piwnica-Worms H. p107wee1 is a dual-specificity kinase that phosphorylates p34cdc2 on tyrosine 15. Proceedings of the National Academy of Sciences of the United States of America. 89: 2917-21. PMID 1372994 DOI: 10.1073/Pnas.89.7.2917  0.482
1992 Lee MS, Ogg S, Xu M, Parker LL, Donoghue DJ, Maller JL, Piwnica-Worms H. cdc25+ encodes a protein phosphatase that dephosphorylates p34cdc2. Molecular Biology of the Cell. 3: 73-84. PMID 1312880 DOI: 10.1091/Mbc.3.1.73  0.302
1991 Parker LL, Atherton-Fessler S, Lee MS, Ogg S, Falk JL, Swenson KI, Piwnica-Worms H. Cyclin promotes the tyrosine phosphorylation of p34cdc2 in a wee1+ dependent manner. The Embo Journal. 10: 1255-63. PMID 1850698 DOI: 10.1002/J.1460-2075.1991.Tb08067.X  0.435
1991 Piwnica-Worms H, Atherton-Fessler S, Lee MS, Ogg S, Swenson KI, Parker LL. p107wee1 is a serine/threonine and tyrosine kinase that promotes the tyrosine phosphorylation of the cyclin/p34cdc2 complex. Cold Spring Harbor Symposia On Quantitative Biology. 56: 567-76. PMID 1840265 DOI: 10.1101/Sqb.1991.056.01.064  0.407
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