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Miklos Guttman, Ph.D. - Publications

Affiliations: 
2009 Chemistry University of California, San Diego, La Jolla, CA 
Area:
Structure, function, dynamics and thermodynamics of protein-protein interactions: NMR, mass spectrometry and kinetics
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44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Mookherjee A, Uppal SS, Murphree TA, Guttman M. Linkage Memory in Underivatized Protonated Carbohydrates. Journal of the American Society For Mass Spectrometry. PMID 33350817 DOI: 10.1021/jasms.0c00440  0.64
2020 Alonge K, Harkewicz R, Guttman M. Rapid differentiation of chondroitin sulfate isomers by gas-phase hydrogen/deuterium exchange. Current Molecular Medicine. PMID 32933460 DOI: 10.2174/1566524020666200915110707  0.321
2020 Guttman M, Padte NN, Huang Y, Yu J, Rocklin GJ, Weitzner BD, Scian M, Ho DD, Lee KK. The influence of proline isomerization on potency and stability of anti-HIV antibody 10E8. Scientific Reports. 10: 14313. PMID 32868832 DOI: 10.1038/S41598-020-71184-7  0.344
2020 Potter ZE, Lau HT, Chakraborty S, Fang L, Guttman M, Ong SE, Fowler DM, Maly DJ. Parallel Chemoselective Profiling for Mapping Protein Structure. Cell Chemical Biology. PMID 32649906 DOI: 10.1016/J.Chembiol.2020.06.014  0.363
2020 Murphree TA, Vorauer C, Brzoska M, Guttman M. Imidazolium Compounds as Internal Exchange Reporters for Hydrogen/Deuterium Exchange by Mass Spectrometry. Analytical Chemistry. PMID 32569457 DOI: 10.1021/Acs.Analchem.0C01328  0.312
2020 Benhaim MA, Mangala Prasad V, Garcia NK, Guttman M, Lee KK. Structural monitoring of a transient intermediate in the hemagglutinin fusion machinery on influenza virions. Science Advances. 6: eaaz8822. PMID 32494683 DOI: 10.1126/Sciadv.Aaz8822  0.342
2020 Uppal SS, Mookherjee A, Harkewicz R, Beasley SE, Bush MF, Guttman M. High-Precision, Gas-Phase Hydrogen/Deuterium Exchange Kinetics by Mass Spectrometry Enabled by Exchange Standards. Analytical Chemistry. PMID 32368904 DOI: 10.1021/Acs.Analchem.0C00749  0.65
2019 Clouser AF, Baughman HE, Basanta B, Guttman M, Nath A, Klevit RE. Interplay of disordered and ordered regions of a human small heat shock protein yields an ensemble of 'quasi-ordered' states. Elife. 8. PMID 31573509 DOI: 10.7554/Elife.50259  0.348
2018 Benhaim M, Lee KK, Guttman M. Tracking Higher Order Protein Structure by Hydrogen-Deuterium Exchange Mass Spectrometry. Protein and Peptide Letters. PMID 30543159 DOI: 10.2174/0929866526666181212165037  0.374
2018 Cook MJ, Delbecq SP, Schweppe TP, Guttman M, Klevit RE, Brzovic PS. The ubiquitin ligase SspH1 from Salmonella uses a modular and dynamic E3 domain to catalyze substrate ubiquitylation. The Journal of Biological Chemistry. PMID 30459234 DOI: 10.1074/Jbc.Ra118.004247  0.332
2018 Mookherjee A, Uppal SS, Guttman M. Dissection of Fragmentation Pathways in Protonated N-acetylhexosamines. Analytical Chemistry. PMID 30216047 DOI: 10.1021/Acs.Analchem.8B01963  0.66
2018 Li MJ, Guttman M, Atkins WM. Conformational dynamics of P-glycoprotein in lipid nanodiscs and detergent micelles reveal complex motions on a wide time scale. The Journal of Biological Chemistry. PMID 29511086 DOI: 10.1074/Jbc.Ra118.002190  0.357
2017 Mookherjee A, Guttman M. Bridging the structural gap of glycoproteomics with ion mobility spectrometry. Current Opinion in Chemical Biology. 42: 86-92. PMID 29202341 DOI: 10.1016/J.Cbpa.2017.11.012  0.324
2017 Torrents de la Peña A, Julien JP, de Taeye SW, Garces F, Guttman M, Ozorowski G, Pritchard LK, Behrens AJ, Go EP, Burger JA, Schermer EE, Sliepen K, Ketas TJ, Pugach P, Yasmeen A, et al. Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization. Cell Reports. 20: 1805-1817. PMID 28834745 DOI: 10.1016/J.Celrep.2017.07.077  0.331
2017 Plotnik D, Guo W, Cleveland B, von Haller P, Eng JK, Guttman M, Lee KK, Arthos J, Hu SL. Extracellular Matrix Proteins Mediate HIV-1 gp120 Interactions with α4β7. Journal of Virology. PMID 28814519 DOI: 10.1128/Jvi.01005-17  0.345
2017 Uppal SS, Beasley SE, Scian M, Guttman M. Gas-phase hydrogen/deuterium exchange for distinguishing isomeric carbohydrate ions. Analytical Chemistry. PMID 28304155 DOI: 10.1021/Acs.Analchem.7B00683  0.668
2016 Verkerke HP, Williams JA, Guttman M, Simonich CA, Liang Y, Filipavicius M, Hu SL, Overbaugh J, Lee KK. Epitope-independent purification of native-like envelope trimers from diverse HIV-1 isolates. Journal of Virology. PMID 27512064 DOI: 10.1128/Jvi.01351-16  0.387
2016 Liang Y, Guttman M, Williams JA, Verkerke H, Alvarado D, Hu SL, Lee KK. Changes in structure and antigenicity of HIV-1 Env trimers resulting from removal of a conserved CD4 binding site-proximal glycan. Journal of Virology. PMID 27489265 DOI: 10.1128/Jvi.01116-16  0.381
2016 Davenport TM, Gorman J, Joyce MG, Zhou T, Soto C, Guttman M, Moquin S, Yang Y, Zhang B, Doria-Rose NA, Hu SL, Mascola JR, Kwong PD, Lee KK. Somatic Hypermutation-Induced Changes in the Structure and Dynamics of HIV-1 Broadly Neutralizing Antibodies. Structure (London, England : 1993). PMID 27477385 DOI: 10.1016/J.Str.2016.06.012  0.326
2016 Guttman M, Lee KK. Site-specific mapping of sialic acid linkage isomers by ion mobility spectrometry. Analytical Chemistry. PMID 27089023 DOI: 10.1021/Acs.Analchem.6B00265  0.351
2016 Liang Y, Guttman M, Davenport TM, Hu SL, Lee KK. Probing the impact of local structural dynamics of conformational epitopes on antibody recognition. Biochemistry. PMID 27003615 DOI: 10.1021/Acs.Biochem.5B01354  0.379
2016 Treuheit NA, Redhair M, Kwon H, McClary WD, Guttman M, Sumida JP, Atkins WM. Membrane Interactions, Ligand-dependent Dynamics, and Stability of Cytochrome P4503A4 in Lipid Nanodiscs. Biochemistry. PMID 26814638 DOI: 10.1021/Acs.Biochem.5B01313  0.704
2016 Guttman M, Wales TE, Whittington D, Engen JR, Brown JM, Lee KK. Tuning a High Transmission Ion Guide to Prevent Gas-Phase Proton Exchange During H/D Exchange MS Analysis. Journal of the American Society For Mass Spectrometry. PMID 26810432 DOI: 10.1007/S13361-015-1330-8  0.332
2016 Guttman M, Lee KK. Isotope Labeling of Biomolecules: Structural Analysis of Viruses by HDX-MS. Methods in Enzymology. 566: 405-26. PMID 26791988 DOI: 10.1016/Bs.Mie.2015.05.021  0.356
2015 de Taeye SW, Ozorowski G, Torrents de la Peña A, Guttman M, Julien JP, van den Kerkhof TL, Burger JA, Pritchard LK, Pugach P, Yasmeen A, Crampton J, Hu J, Bontjer I, Torres JL, Arendt H, et al. Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes. Cell. 163: 1702-15. PMID 26687358 DOI: 10.1016/J.Cell.2015.11.056  0.324
2015 Gupta S, Guttman M, Leverenz RL, Zhumadilova K, Pawlowski EG, Petzold CJ, Lee KK, Ralston CY, Kerfeld CA. Local and global structural drivers for the photoactivation of the orange carotenoid protein. Proceedings of the National Academy of Sciences of the United States of America. PMID 26385969 DOI: 10.1073/Pnas.1512240112  0.335
2015 Ringe RP, Yasmeen A, Ozorowski G, Go EP, Pritchard LK, Guttman M, Ketas TA, Cottrell CA, Wilson IA, Sanders RW, Cupo A, Crispin M, Lee KK, Desaire H, Ward AB, et al. Influences on the design and purification of soluble, recombinant native-like HIV-1 envelope glycoprotein trimers. Journal of Virology. PMID 26311893 DOI: 10.1128/Jvi.01768-15  0.337
2015 Do Kwon Y, Pancera M, Acharya P, Georgiev IS, Crooks ET, Gorman J, Joyce MG, Guttman M, Ma X, Narpala S, Soto C, Terry DS, Yang Y, Zhou T, Ahlsen G, et al. Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env. Nature Structural & Molecular Biology. 22: 522-31. PMID 26098315 DOI: 10.1038/Nsmb.3051  0.371
2015 Garcia NK, Guttman M, Ebner JL, Lee KK. Dynamic changes during acid-induced activation of influenza hemagglutinin. Structure (London, England : 1993). 23: 665-76. PMID 25773144 DOI: 10.1016/J.Str.2015.02.006  0.314
2015 Guttman M, Cupo A, Julien JP, Sanders RW, Wilson IA, Moore JP, Lee KK. Antibody potency relates to the ability to recognize the closed, pre-fusion form of HIV Env. Nature Communications. 6: 6144. PMID 25652336 DOI: 10.1038/Ncomms7144  0.383
2014 Guttman M, Garcia NK, Cupo A, Matsui T, Julien JP, Sanders RW, Wilson IA, Moore JP, Lee KK. CD4-induced activation in a soluble HIV-1 Env trimer. Structure (London, England : 1993). 22: 974-84. PMID 24931470 DOI: 10.1016/J.Str.2014.05.001  0.315
2013 Guttman M, Weis DD, Engen JR, Lee KK. Analysis of overlapped and noisy hydrogen/deuterium exchange mass spectra. Journal of the American Society For Mass Spectrometry. 24: 1906-12. PMID 24018862 DOI: 10.1007/S13361-013-0727-5  0.303
2013 Guttman M, Lee KK. A functional interaction between gp41 and gp120 is observed for monomeric but not oligomeric, uncleaved HIV-1 Env gp140. Journal of Virology. 87: 11462-75. PMID 23966389 DOI: 10.1128/Jvi.01681-13  0.324
2013 Davenport TM, Guttman M, Guo W, Cleveland B, Kahn M, Hu SL, Lee KK. Isolate-specific differences in the conformational dynamics and antigenicity of HIV-1 gp120. Journal of Virology. 87: 10855-73. PMID 23903848 DOI: 10.1128/Jvi.01535-13  0.357
2012 Guttman M, Kahn M, Garcia NK, Hu SL, Lee KK. Solution structure, conformational dynamics, and CD4-induced activation in full-length, glycosylated, monomeric HIV gp120. Journal of Virology. 86: 8750-64. PMID 22674993 DOI: 10.1128/Jvi.07224-11  0.385
2011 Guttman M, Komives EA. The structure, dynamics, and binding of the LA45 module pair of the low-density lipoprotein receptor suggest an important role for LA4 in ligand release. Biochemistry. 50: 11001-8. PMID 22091758 DOI: 10.1021/Bi2014486  0.593
2011 Guttman M, Scian M, Lee KK. Tracking hydrogen/deuterium exchange at glycan sites in glycoproteins by mass spectrometry. Analytical Chemistry. 83: 7492-9. PMID 21863800 DOI: 10.1021/Ac201729V  0.313
2011 Mulvihill MM, Guttman M, Komives EA. Protein interactions among Fe65, the low-density lipoprotein receptor-related protein, and the amyloid precursor protein. Biochemistry. 50: 6208-16. PMID 21650223 DOI: 10.1021/Bi200508F  0.704
2010 Guttman M, Prieto JH, Handel TM, Domaille PJ, Komives EA. Structure of the minimal interface between ApoE and LRP. Journal of Molecular Biology. 398: 306-19. PMID 20303980 DOI: 10.1016/J.Jmb.2010.03.022  0.76
2010 Guttman M, Prieto JH, Croy JE, Komives EA. Decoding of lipoprotein-receptor interactions: properties of ligand binding modules governing interactions with apolipoprotein E. Biochemistry. 49: 1207-16. PMID 20030366 DOI: 10.1021/Bi9017208  0.7
2010 Guttman M, Komives E. Fusion construct of CR17 from LRP-1 and ApoE residues 130-149 Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Kny/Pdb  0.527
2010 Guttman M, Komives E. Solution Structure of complement repeat CR17 from LRP-1 Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Knx/Pdb  0.52
2009 Guttman M, Betts GN, Barnes H, Ghassemian M, van der Geer P, Komives EA. Interactions of the NPXY microdomains of the low density lipoprotein receptor-related protein 1. Proteomics. 9: 5016-28. PMID 19771558 DOI: 10.1002/Pmic.200900457  0.565
2009 Gertsman I, Gan L, Guttman M, Lee K, Speir JA, Duda RL, Hendrix RW, Komives EA, Johnson JE. An unexpected twist in viral capsid maturation. Nature. 458: 646-50. PMID 19204733 DOI: 10.1038/Nature07686  0.548
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