| Year |
Citation |
Score |
| 2017 |
Poi MJ, Knobloch TJ, Li J. Deletion of RD(INK4/ARF) enhancer: A novel mutation to "inactivate" the INK4-ARF locus. Dna Repair. 57: 50-55. PMID 28688373 DOI: 10.1016/J.Dnarep.2017.06.027 |
0.48 |
|
| 2017 |
Poi MJ, Li J, Sborov DW, VanGundy Z, Cho YK, Lamprecht M, Pichiorri F, Phelps MA, Hofmeister CC. Polymorphism in ANRIL is associated with relapse in patients with multiple myeloma after autologous stem cell transplant. Molecular Carcinogenesis. PMID 28150872 DOI: 10.1002/Mc.22626 |
0.37 |
|
| 2015 |
Poi MJ, Knobloch TJ, Sears MT, Warner BM, Uhrig LK, Weghorst CM, Li J. Alterations in RD(INK4/ARF) -mediated en bloc regulation of the INK4-ARF locus in human squamous cell carcinoma of the head and neck. Molecular Carcinogenesis. 54: 532-42. PMID 24302590 DOI: 10.1002/Mc.22119 |
0.449 |
|
| 2014 |
Poi MJ, Drosdeck J, Frankel WL, Muscarella P, Li J. Deletions of RDINK4/ARF enhancer in gastrinomas and nonfunctioning pancreatic neuroendocrine tumors. Pancreas. 43: 1009-13. PMID 25003221 DOI: 10.1097/Mpa.0000000000000165 |
0.427 |
|
| 2014 |
Li J, Knobloch TJ, Poi MJ, Zhang Z, Davis AT, Muscarella P, Weghorst CM. Genetic alterations of RD(INK4/ARF) enhancer in human cancer cells. Molecular Carcinogenesis. 53: 211-8. PMID 23065809 DOI: 10.1002/Mc.21965 |
0.487 |
|
| 2013 |
Yuan C, Guo Y, Zhu L, Guo W, Mahajan A, Weghorst CM, Li J. The study of pH-dependent stability shows that the TPLH-mediated hydrogen-bonding network is important for the conformation and stability of human gankyrin. Biochemistry. 52: 4848-57. PMID 23777370 DOI: 10.1021/Bi4005717 |
0.325 |
|
| 2013 |
Poi MJ, Knobloch TJ, Yuan C, Tsai MD, Weghorst CM, Li J. Evidence that P12, a specific variant of P16(INK4A), plays a suppressive role in human pancreatic carcinogenesis. Biochemical and Biophysical Research Communications. 436: 217-22. PMID 23727582 DOI: 10.1016/J.Bbrc.2013.05.078 |
0.626 |
|
| 2011 |
Li J, Poi MJ, Tsai MD. Regulatory mechanisms of tumor suppressor P16(INK4A) and their relevance to cancer. Biochemistry. 50: 5566-82. PMID 21619050 DOI: 10.1021/Bi200642E |
0.612 |
|
| 2010 |
Li J, Guo Y. Gankyrin Oncoprotein: Structure, Function, and Involvement in Cancer. Current Chemical Biology. 4: 13-19. PMID 32775187 DOI: 10.2174/2212796811004010013 |
0.402 |
|
| 2010 |
Guo Y, Yuan C, Tian F, Huang K, Weghorst CM, Tsai MD, Li J. Contributions of conserved TPLH tetrapeptides to the conformational stability of ankyrin repeat proteins. Journal of Molecular Biology. 399: 168-81. PMID 20398677 DOI: 10.1016/J.Jmb.2010.04.010 |
0.526 |
|
| 2010 |
Guo Y, Yuan C, Weghorst CM, Li J. IKKbeta specifically binds to P16 and phosphorylates Ser8 of P16. Biochemical and Biophysical Research Communications. 393: 504-8. PMID 20152798 DOI: 10.1016/J.Bbrc.2010.02.035 |
0.478 |
|
| 2009 |
Guo Y, Mahajan A, Yuan C, Joo SH, Weghorst CM, Tsai MD, Li J. Comparisons of the conformational stability of cyclin-dependent kinase (CDK) 4-interacting ankyrin repeat (AR) proteins. Biochemistry. 48: 4050-62. PMID 19320462 DOI: 10.1021/Bi802247P |
0.58 |
|
| 2008 |
Muscarella P, Bloomston M, Brewer AR, Mahajan A, Frankel WL, Ellison EC, Farrar WB, Weghorst CM, Li J. Expression of the p16INK4A/Cdkn2a gene is prevalently downregulated in human pheochromocytoma tumor specimens. Gene Expression. 14: 207-16. PMID 19110720 DOI: 10.3727/105221608786883825 |
0.434 |
|
| 2008 |
Li J, Warner B, Casto BC, Knobloch TJ, Weghorst CM. Tumor suppressor p16(INK4A)/Cdkn2a alterations in 7, 12-dimethylbenz(a)anthracene (DMBA)-induced hamster cheek pouch tumors. Molecular Carcinogenesis. 47: 733-8. PMID 18247379 DOI: 10.1002/Mc.20424 |
0.457 |
|
| 2007 |
Mahajan A, Guo Y, Yuan C, Weghorst CM, Tsai MD, Li J. Dissection of protein-protein interaction and CDK4 inhibition in the oncogenic versus tumor suppressing functions of gankyrin and P16. Journal of Molecular Biology. 373: 990-1005. PMID 17881001 DOI: 10.1016/J.Jmb.2007.08.038 |
0.67 |
|
| 2006 |
Li J, Mahajan A, Tsai MD. Ankyrin repeat: a unique motif mediating protein-protein interactions. Biochemistry. 45: 15168-78. PMID 17176038 DOI: 10.1021/Bi062188Q |
0.534 |
|
| 2006 |
Li J, Zhu J, Melvin WS, Bekaii-Saab TS, Chen CS, Muscarella P. A structurally optimized celecoxib derivative inhibits human pancreatic cancer cell growth. Journal of Gastrointestinal Surgery : Official Journal of the Society For Surgery of the Alimentary Tract. 10: 207-14. PMID 16455452 DOI: 10.1016/J.Gassur.2005.07.025 |
0.357 |
|
| 2005 |
Li J, Muscarella P, Joo SH, Knobloch TJ, Melvin WS, Weghorst CM, Tsai MD. Dissection of CDK4-binding and transactivation activities of p34(SEI-1) and comparison between functions of p34(SEI-1) and p16(INK4A). Biochemistry. 44: 13246-56. PMID 16201750 DOI: 10.1021/Bi0504658 |
0.626 |
|
| 2004 |
Yuan C, Li J, Mahajan A, Poi MJ, Byeon IJ, Tsai MD. Solution structure of the human oncogenic protein gankyrin containing seven ankyrin repeats and analysis of its structure--function relationship. Biochemistry. 43: 12152-61. PMID 15379554 DOI: 10.1021/Bi049116O |
0.587 |
|
| 2004 |
Li J, Melvin WS, Tsai MD, Muscarella P. The nuclear protein p34SEI-1 regulates the kinase activity of cyclin-dependent kinase 4 in a concentration-dependent manner. Biochemistry. 43: 4394-9. PMID 15065884 DOI: 10.1021/Bi035601S |
0.628 |
|
| 2004 |
Li J, Weghorst CM, Tsutsumi M, Poi MJ, Knobloch TJ, Casto BC, Melvin WS, Tsai MD, Muscarella P. Frequent p16INK4A/CDKN2A alterations in chemically induced Syrian golden hamster pancreatic tumors. Carcinogenesis. 25: 263-8. PMID 14604895 DOI: 10.1093/Carcin/Bgh007 |
0.585 |
|
| 2003 |
Li J, Joo SH, Tsai MD. An NF-kappaB-specific inhibitor, IkappaBalpha, binds to and inhibits cyclin-dependent kinase 4. Biochemistry. 42: 13476-83. PMID 14621993 DOI: 10.1021/Bi035390R |
0.58 |
|
| 2003 |
Li J, Li H, Tsai MD. Direct binding of the N-terminus of HTLV-1 tax oncoprotein to cyclin-dependent kinase 4 is a dominant path to stimulate the kinase activity. Biochemistry. 42: 6921-8. PMID 12779347 DOI: 10.1021/Bi034369N |
0.678 |
|
| 2003 |
Li J, Qin D, Knobloch TJ, Tsai MD, Weghorst CM, Melvin WS, Muscarella P. Expression and characterization of Syrian golden hamster p16, a homologue of human tumor suppressor p16 INK4A. Biochemical and Biophysical Research Communications. 304: 241-7. PMID 12711305 DOI: 10.1016/S0006-291X(03)00577-1 |
0.705 |
|
| 2002 |
Li J, Tsai MD. Novel insights into the INK4-CDK4/6-Rb pathway: counter action of gankyrin against INK4 proteins regulates the CDK4-mediated phosphorylation of Rb. Biochemistry. 41: 3977-83. PMID 11900540 DOI: 10.1021/bi011550s |
0.552 |
|
| 2001 |
Poi MJ, Yen T, Li J, Song H, Lang JC, Schuller DE, Pearl DK, Casto BC, Tsai MD, Weghorst CM. Somatic INK4a-ARF locus mutations: a significant mechanism of gene inactivation in squamous cell carcinomas of the head and neck. Molecular Carcinogenesis. 30: 26-36. PMID 11255261 DOI: 10.1002/1098-2744(200101)30:1<26::Aid-Mc1010>3.0.Co;2-E |
0.679 |
|
| 2000 |
Yuan C, Selby TL, Li J, Byeon IJ, Tsai MD. Tumor suppressor INK4: refinement of p16INK4A structure and determination of p15INK4B structure by comparative modeling and NMR data. Protein Science : a Publication of the Protein Society. 9: 1120-8. PMID 10892805 DOI: 10.1110/Ps.9.6.1120 |
0.569 |
|
| 2000 |
Li J, Poi MJ, Qin D, Selby TL, Byeon IJ, Tsai MD. Tumor suppressor INK4: quantitative structure-function analyses of p18INK4C as an inhibitor of cyclin-dependent kinase 4. Biochemistry. 39: 649-57. PMID 10651629 DOI: 10.1021/Bi991281U |
0.713 |
|
| 1999 |
Yuan C, Li J, Selby TL, Byeon IJ, Tsai MD. Tumor suppressor INK4: comparisons of conformational properties between p16(INK4A) and p18(INK4C). Journal of Molecular Biology. 294: 201-11. PMID 10556039 DOI: 10.1006/Jmbi.1999.3231 |
0.621 |
|
| 1999 |
Li J, Byeon IJ, Ericson K, Poi MJ, O'Maille P, Selby T, Tsai MD. Tumor suppressor INK4: determination of the solution structure of p18INK4C and demonstration of the functional significance of loops in p18INK4C and p16INK4A. Biochemistry. 38: 2930-40. PMID 10074345 DOI: 10.1021/Bi982286E |
0.742 |
|
| 1998 |
Byeon IJ, Li J, Ericson K, Selby TL, Tevelev A, Kim HJ, O'Maille P, Tsai MD. Tumor suppressor p16INK4A: determination of solution structure and analyses of its interaction with cyclin-dependent kinase 4. Molecular Cell. 1: 421-31. PMID 9660926 DOI: 10.1016/S1097-2765(00)80042-8 |
0.724 |
|
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