Daniel Dykhuizen - Publications

Affiliations: 
Stony Brook University, Stony Brook, NY, United States 

72 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Spagnolo F, Cristofari P, Tatonetti NP, Ginzburg LR, Dykhuizen DE. Pathogen population structure can explain hospital outbreaks. The Isme Journal. PMID 30046167 DOI: 10.1038/S41396-018-0235-5  0.554
2018 Warsi OM, Andersson DI, Dykhuizen DE. Different adaptive strategies in E. coli populations evolving under macronutrient limitation and metal ion limitation. Bmc Evolutionary Biology. 18: 72. PMID 29776341 DOI: 10.1186/S12862-018-1191-4  0.739
2017 Warsi OM, Dykhuizen DE. Evolutionary implications of Liebig's law of the minimum: Selection under low concentrations of two nonsubstitutable nutrients. Ecology and Evolution. 7: 5296-5309. PMID 28770068 DOI: 10.1002/Ece3.3096  0.74
2016 Dykhuizen D. Thoughts Toward a Theory of Natural Selection: The Importance of Microbial Experimental Evolution. Cold Spring Harbor Perspectives in Biology. PMID 26747663 DOI: 10.1101/cshperspect.a018044  0.414
2015 Spagnolo F, Rinaldi C, Sajorda DR, Dykhuizen DE. Evolution of Resistance to Continuously Increasing Streptomycin Concentrations in Populations of Escherichia coli. Antimicrobial Agents and Chemotherapy. 60: 1336-42. PMID 26666944 DOI: 10.1128/Aac.01359-15  0.552
2014 Monzón J, Kays R, Dykhuizen DE. Assessment of coyote-wolf-dog admixture using ancestry-informative diagnostic SNPs. Molecular Ecology. 23: 182-97. PMID 24148003 DOI: 10.1111/Mec.12570  0.718
2012 Weissman SJ, Johnson JR, Tchesnokova V, Billig M, Dykhuizen D, Riddell K, Rogers P, Qin X, Butler-Wu S, Cookson BT, Fang FC, Scholes D, Chattopadhyay S, Sokurenko E. High-resolution two-locus clonal typing of extraintestinal pathogenic Escherichia coli. Applied and Environmental Microbiology. 78: 1353-60. PMID 22226951 DOI: 10.1128/Aem.06663-11  0.352
2010 Stoebel DM, Dykhuizen DE. Waste and yet want not. Molecular Cell. 38: 625-6. PMID 20541995 DOI: 10.1016/J.Molcel.2010.05.028  0.695
2010 Brisson D, Vandermause MF, Meece JK, Reed KD, Dykhuizen DE. Evolution of northeastern and midwestern Borrelia burgdorferi, United States. Emerging Infectious Diseases. 16: 911-7. PMID 20507740 DOI: 10.3201/Eid1606.090329  0.512
2009 Zhong S, Miller SP, Dykhuizen DE, Dean AM. Transcription, translation, and the evolution of specialists and generalists. Molecular Biology and Evolution. 26: 2661-78. PMID 19706726 DOI: 10.1093/Molbev/Msp187  0.515
2009 Chattopadhyay S, Paranjpye RN, Dykhuizen DE, Sokurenko EV, Strom MS. Comparative evolutionary analysis of the major structural subunit of Vibrio vulnificus type IV pili. Molecular Biology and Evolution. 26: 2185-96. PMID 19556347 DOI: 10.1093/molbev/msp124  0.303
2009 Dykhuizen DE, Dean AM. Experimental evolution from the bottom up Experimental Evolution: Concepts, Methods, and Applications of Selection Experiments. 86-106.  0.475
2008 Dykhuizen DE, Brisson D, Sandigursky S, Wormser GP, Nowakowski J, Nadelman RB, Schwartz I. The propensity of different Borrelia burgdorferi sensu stricto genotypes to cause disseminated infections in humans. The American Journal of Tropical Medicine and Hygiene. 78: 806-10. PMID 18458317 DOI: 10.4269/Ajtmh.2008.78.806  0.508
2008 Stoebel DM, Dean AM, Dykhuizen DE. The cost of expression of Escherichia coli lac operon proteins is in the process, not in the products. Genetics. 178: 1653-60. PMID 18245823 DOI: 10.1534/Genetics.107.085399  0.756
2008 Brisson D, Dykhuizen DE, Ostfeld RS. Conspicuous impacts of inconspicuous hosts on the Lyme disease epidemic. Proceedings. Biological Sciences / the Royal Society. 275: 227-35. PMID 18029304 DOI: 10.1098/Rspb.2007.1208  0.494
2007 Chattopadhyay S, Feldgarden M, Weissman SJ, Dykhuizen DE, van Belle G, Sokurenko EV. Haplotype diversity in "source-sink" dynamics of Escherichia coli urovirulence. Journal of Molecular Evolution. 64: 204-14. PMID 17177088 DOI: 10.1007/S00239-006-0063-5  0.69
2006 Brisson D, Dykhuizen DE. A modest model explains the distribution and abundance of Borrelia burgdorferi strains. The American Journal of Tropical Medicine and Hygiene. 74: 615-22. PMID 16606995 DOI: 10.4269/Ajtmh.2006.74.615  0.534
2006 Weissman SJ, Chattopadhyay S, Aprikian P, Obata-Yasuoka M, Yarova-Yarovaya Y, Stapleton A, Ba-Thein W, Dykhuizen D, Johnson JR, Sokurenko EV. Clonal analysis reveals high rate of structural mutations in fimbrial adhesins of extraintestinal pathogenic Escherichia coli. Molecular Microbiology. 59: 975-88. PMID 16420365 DOI: 10.1111/j.1365-2958.2005.04985.x  0.406
2004 Brisson D, Dykhuizen DE. ospC diversity in Borrelia burgdorferi: different hosts are different niches. Genetics. 168: 713-22. PMID 15514047 DOI: 10.1534/Genetics.104.028738  0.583
2004 Dykhuizen DE, Dean AM. Evolution of specialists in an experimental microcosm. Genetics. 167: 2015-26. PMID 15342537 DOI: 10.1534/Genetics.103.025205  0.56
2004 Zhong S, Khodursky A, Dykhuizen DE, Dean AM. Evolutionary genomics of ecological specialization. Proceedings of the National Academy of Sciences of the United States of America. 101: 11719-24. PMID 15289609 DOI: 10.1073/Pnas.0404397101  0.512
2004 Sokurenko EV, Feldgarden M, Trintchina E, Weissman SJ, Avagyan S, Chattopadhyay S, Johnson JR, Dykhuizen DE. Selection footprint in the FimH adhesin shows pathoadaptive niche differentiation in Escherichia coli. Molecular Biology and Evolution. 21: 1373-83. PMID 15044596 DOI: 10.1093/Molbev/Msh136  0.679
2003 Feldgarden M, Stoebel DM, Brisson D, Dykhuizen DE. SIZE DOESN'T MATTER: MICROBIAL SELECTION EXPERIMENTS ADDRESS ECOLOGICAL PHENOMENA. Ecology. 84: 1679-1687. PMID 21423836 DOI: 10.1890/0012-9658(2003)084[1679:Sdmmse]2.0.Co;2  0.761
2002 Lunzer M, Natarajan A, Dykhuizen DE, Dean AM. Enzyme kinetics, substitutable resources and competition: from biochemistry to frequency-dependent selection in lac. Genetics. 162: 485-99. PMID 12242256  0.553
2002 Qiu WG, Dykhuizen DE, Acosta MS, Luft BJ. Geographic uniformity of the Lyme disease spirochete (Borrelia burgdorferi) and its shared history with tick vector (Ixodes scapularis) in the Northeastern United States. Genetics. 160: 833-49. PMID 11901105  0.488
2001 Wang IN, Dykhuizen DE. Variation of enzyme activities at a branched pathway involved in the utilization of gluconate in Escherichia coli. Evolution; International Journal of Organic Evolution. 55: 897-908. PMID 11430650 DOI: 10.1554/0014-3820(2001)055[0897:Voeaaa]2.0.Co;2  0.549
2001 Baranton G, Seinost G, Theodore G, Postic D, Dykhuizen D. Distinct levels of genetic diversity of Borrelia burgdorferi are associated with different aspects of pathogenicity. Research in Microbiology. 152: 149-56. PMID 11316368 DOI: 10.1016/S0923-2508(01)01186-X  0.301
2000 Rannala B, Qiu WG, Dykhuizen DE. Methods for estimating gene frequencies and detecting selection in bacterial populations. Genetics. 155: 499-508. PMID 10835376  0.478
1999 Tuomanen E, Sokurenko EV, Dykhuizen DE. Divergence in the background: Hard to measure but the key to being the best of the best Trends in Microbiology. 7: 271-272. PMID 10390635 DOI: 10.1016/S0966-842X(99)01528-0  0.309
1999 Seinost G, Dykhuizen DE, Dattwyler RJ, Golde WT, Dunn JJ, Wang IN, Wormser GP, Schriefer ME, Luft BJ. Four clones of Borrelia burgdorferi sensu stricto cause invasive infection in humans. Infection and Immunity. 67: 3518-24. PMID 10377134 DOI: 10.1128/Iai.67.7.3518-3524.1999  0.512
1999 Wang IN, Dykhuizen DE, Qiu W, Dunn JJ, Bosler EM, Luft BJ. Genetic diversity of ospC in a local population of Borrelia burgdorferi sensu stricto. Genetics. 151: 15-30. PMID 9872945  0.648
1998 Golde WT, Robinson-Dunn B, Stobierski MG, Dykhuizen D, Wang IN, Carlson V, Stiefel H, Shiflett S, Campbell GL. Culture-confirmed reinfection of a person with different strains of Borrelia burgdorferi sensu stricto. Journal of Clinical Microbiology. 36: 1015-9. PMID 9542928 DOI: 10.1128/Jcm.36.4.1015-1019.1998  0.572
1997 Qiu WG, Bosler EM, Campbell JR, Ugine GD, Wang IN, Luft BJ, Dykhuizen DE. A population genetic study of Borrelia burgdorferi sensu stricto from eastern Long Island, New York, suggested frequency-dependent selection, gene flow and host adaptation. Hereditas. 127: 203-16. PMID 9474903 DOI: 10.1111/J.1601-5223.1997.00203.X  0.673
1996 Guttman DS, Wang PW, Wang IN, Bosler EM, Luft BJ, Dykhuizen DE. Multiple infections of Ixodes scapularis ticks by Borrelia burgdorferi as revealed by single-strand conformation polymorphism analysis. Journal of Clinical Microbiology. 34: 652-6. PMID 8904432 DOI: 10.1128/Jcm.34.3.652-656.1996  0.638
1996 Wang IN, Dykhuizen DE, Slobodkin LB. The evolution of phage lysis timing Evolutionary Ecology. 10: 545-558. DOI: 10.1007/Bf01237884  0.492
1995 McGrath BC, Dunn JJ, Gorgone G, Guttman D, Dykhuizen D, Luft BJ. Identification of an immunologically important hypervariable domain of major outer surface protein A of Borrelia burgdorferi. Infection and Immunity. 63: 1356-61. PMID 7890394 DOI: 10.1128/Iai.63.4.1356-1361.1995  0.553
1994 Guttman DS, Dykhuizen DE. Clonal divergence in Escherichia coli as a result of recombination, not mutation. Science (New York, N.Y.). 266: 1380-3. PMID 7973728 DOI: 10.1126/Science.7973728  0.566
1994 Guttman DS, Dykhuizen DE. Detecting selective sweeps in naturally occurring Escherichia coli. Genetics. 138: 993-1003. PMID 7896119  0.599
1994 Dykhuizen DE, Dean AM. Predicted fitness changes along an environmental gradient Evolutionary Ecology. 8: 524-541. DOI: 10.1007/Bf01238256  0.537
1993 Silva PJN, Dykhuizen DE. THE INCREASED POTENTIAL FOR SELECTION OF THE LAC OPERON OF ESCHERICHIA COLI. Evolution; International Journal of Organic Evolution. 47: 741-749. PMID 28567900 DOI: 10.1111/j.1558-5646.1993.tb01230.x  0.501
1990 Dykhuizen DE, Dean AM. Enzyme activity and fitness: Evolution in solution. Trends in Ecology & Evolution. 5: 257-62. PMID 21232368 DOI: 10.1016/0169-5347(90)90067-N  0.538
1989 Lawrence JG, Dykhuizen DE, DuBose RF, Hartl DL. Phylogenetic analysis using insertion sequence fingerprinting in Escherichia coli. Molecular Biology and Evolution. 6: 1-14. PMID 2564160 DOI: 10.1093/Oxfordjournals.Molbev.A040531  0.675
1988 Dean AM, Dykhuizen DE, Hartl DL. Fitness effects of amino acid replacements in the beta-galactosidase of Escherichia coli. Molecular Biology and Evolution. 5: 469-85. PMID 3143044 DOI: 10.1093/Oxfordjournals.Molbev.A040513  0.7
1988 DuBose RF, Dykhuizen DE, Hartl DL. Genetic exchange among natural isolates of bacteria: recombination within the phoA gene of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 85: 7036-40. PMID 3045828 DOI: 10.1073/Pnas.85.18.7036  0.628
1988 Miller RD, Dykhuizen DE, Hartl DL. Fitness effects of a deletion mutation increasing transcription of the 6-phosphogluconate dehydrogenase gene in Escherichia coli. Molecular Biology and Evolution. 5: 691-703. PMID 2464736 DOI: 10.1093/Oxfordjournals.Molbev.A040522  0.641
1987 Sawyer SA, Dykhuizen DE, Hartl DL. Confidence interval for the number of selectively neutral amino acid polymorphisms. Proceedings of the National Academy of Sciences of the United States of America. 84: 6225-8. PMID 3306673 DOI: 10.1073/Pnas.84.17.6225  0.602
1987 Dykhuizen DE, Dean AM, Hartl DL. Metabolic flux and fitness. Genetics. 115: 25-31. PMID 3104135  0.711
1987 Sawyer SA, Dykhuizen DE, DuBose RF, Green L, Mutangadura-Mhlanga T, Wolczyk DF, Hartl DL. Distribution and abundance of insertion sequences among natural isolates of Escherichia coli. Genetics. 115: 51-63. PMID 3030884  0.608
1986 Hartl DL, Dean AM, Dykhuizen DE. The molecular biology of natural selection: reply to burton and place. Genetics. 114: 1037-9. PMID 17246353  0.679
1986 Dean AM, Dykhuizen DE, Hartl DL. Fitness as a function of beta-galactosidase activity in Escherichia coli. Genetical Research. 48: 1-8. PMID 3096817 DOI: 10.1017/S0016672300024587  0.654
1986 Hartl DL, Medhora M, Green L, Dykhuizen DE. The evolution of DNA sequences in Escherichia coli. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 312: 191-204. PMID 2870515 DOI: 10.1098/Rstb.1986.0001  0.596
1985 Dykhuizen DE, Mudd C, Honeycutt A, Hartl DL. POLYMORPHIC POSTTRANSLATIONAL MODIFICATION OF ALKALINE PHOSPHATASE IN ESCHERICHIA COLI. Evolution; International Journal of Organic Evolution. 39: 1-7. PMID 28563640 DOI: 10.1111/J.1558-5646.1985.Tb04075.X  0.607
1985 Hartl DL, Dykhuizen DE, Dean AM. Limits of adaptation: the evolution of selective neutrality. Genetics. 111: 655-74. PMID 3932127  0.704
1985 Dykhuizen DE, Sawyer SA, Green L, Miller RD, Hartl DL. Joint distribution of insertion elements IS4 and IS5 in natural isolates of Escherichia coli. Genetics. 111: 219-31. PMID 2996976  0.6
1984 Dykhuizen DE, de Framond J, Hartl DL. Selective neutrality of glucose-6-phosphate dehydrogenase allozymes in Escherichia coli. Molecular Biology and Evolution. 1: 162-70. PMID 6400649 DOI: 10.1093/Oxfordjournals.Molbev.A040309  0.631
1984 Miller RD, Dykhuizen DE, Green L, Hartl DL. Specific deletion occurring in the directed evolution of 6-phosphogluconate dehydrogenase in Escherichia coli. Genetics. 108: 765-72. PMID 6392014  0.62
1984 Dykhuizen DE, de Framond J, Hartl DL. Potential for hitchhiking in the eda-edd-zwf gene cluster of Escherichia coli. Genetical Research. 43: 229-39. PMID 6381229 DOI: 10.1017/S0016672300026021  0.547
1984 Hartl DL, Dykhuizen DE, Berg DE. Accessory DNAs in the bacterial gene pool: playground for coevolution. Ciba Foundation Symposium. 102: 233-45. PMID 6319094 DOI: 10.1002/9780470720837.ch15  0.623
1984 Hartl DL, Dykhuizen DE. The population genetics of Escherichia coli. Annual Review of Genetics. 18: 31-68. PMID 6099090 DOI: 10.1146/Annurev.Ge.18.120184.000335  0.645
1984 Green L, Miller RD, Dykhuizen DE, Hartl DL. Distribution of DNA insertion element IS5 in natural isolates of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 81: 4500-4. PMID 6087327 DOI: 10.1073/Pnas.81.14.4500  0.601
1983 Dykhuizen DE, Hartl DL. Functional effects of PGI allozymes in Escherichia coli. Genetics. 105: 1-18. PMID 6352406  0.639
1983 Hartl DL, Dykhuizen DE, Miller RD, Green L, de Framond J. Transposable element IS50 improves growth rate of E. coli cells without transposition. Cell. 35: 503-10. PMID 6317194 DOI: 10.1016/0092-8674(83)90184-8  0.619
1983 Dykhuizen DE, Hartl DL. Selection in chemostats. Microbiological Reviews. 47: 150-68. PMID 6308409 DOI: 10.1128/Mmbr.47.2.150-168.1983  0.577
1981 Dykhuizen D, Hartl D. EVOLUTION OF COMPETITIVE ABILITY IN ESCHERICHIA COLI. Evolution; International Journal of Organic Evolution. 35: 581-594. PMID 28563589 DOI: 10.1111/J.1558-5646.1981.Tb04919.X  0.681
1981 Hartl DL, Dykhuizen DE. Potential for selection among nearly neutral allozymes of 6-phosphogluconate dehydrogenase in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 78: 6344-8. PMID 7031648 DOI: 10.1073/Pnas.78.10.6344  0.639
1980 Dykhuizen D, Hartl DL. Selective neutrality of 6PGD allozymes in E. coli and the effects of genetic background. Genetics. 96: 801-17. PMID 7021316  0.653
1980 Dykhuizen D, Davies M. An Experimental Model: Bacterial Specialists and Generalists Competing in Chemostats Ecology. 61: 1213-1227. DOI: 10.2307/1936839  0.385
1980 Dykhuizen D, Hartl D. Molecular clockwork (reply) Nature. 287: 90. DOI: 10.1038/287090A0  0.554
1979 Hartl D, Dykhuizen D. A selectively driven molecular clock. Nature. 281: 230-1. PMID 384266 DOI: 10.1038/281230A0  0.648
1978 Dykhuizen D, Hartl D. Transport by the lactose permease of Escherichia coli as the basis of lactose killing. Journal of Bacteriology. 135: 876-82. PMID 99437 DOI: 10.1128/JB.135.3.876-882.1978  0.549
1973 Dykhuizen D. Genetic analysis of the system that reduces biotin-d-sulfoxide in Escherichia coli. Journal of Bacteriology. 115: 662-7. PMID 4579877 DOI: 10.1128/Jb.115.2.662-667.1973  0.326
1972 Shizuya H, Dykhuizen D. Conditional lethality of deletions which include uvrB in strains of Escherichia coli lacking deoxyribonucleic acid polymerase I. Journal of Bacteriology. 112: 676-81. PMID 4563970 DOI: 10.1128/Jb.112.2.676-681.1972  0.334
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