Charles E. McKenna - Publications

Affiliations: 
University of Southern California, Los Angeles, CA, United States 
Area:
organophosphorus, bioorganic and medicinal chemistry

103 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Jacobs MR, Olivero JE, Ok Choi H, Liao CP, Kashemirov BA, Katz JE, Gross ME, McKenna CE. Synthesis and anti-cancer potential of potent peripheral MAOA inhibitors designed to limit blood:brain penetration. Bioorganic & Medicinal Chemistry. 92: 117425. PMID 37544256 DOI: 10.1016/j.bmc.2023.117425  0.567
2023 Mustafa D, Overhulse JM, Kashemirov BA, McKenna CE. Microwave-Accelerated McKenna Synthesis of Phosphonic Acids: An Investigation. Molecules (Basel, Switzerland). 28. PMID 37110732 DOI: 10.3390/molecules28083497  0.527
2020 Haratipour P, Minard C, Nakhjiri M, Negahbani A, Chamberlain BT, Osuna J, Upton TG, Zhao M, Kashemirov BA, McKenna CE. Completing the β,γ-CXY-dNTP Stereochemical Probe Toolkit: Synthetic Access to the dCTP Diastereomers and P and F NMR Correlations with Absolute Configurations. The Journal of Organic Chemistry. PMID 33125847 DOI: 10.1021/acs.joc.0c01204  0.766
2020 Batra VK, Alnajjar KS, Sweasy JB, McKenna CE, Goodman MF, Wilson SH. Revealing an internal stabilization deficiency in the DNA polymerase β K289M cancer variant through combined use of chemical biology and X-ray crystallography. Biochemistry. PMID 31999437 DOI: 10.1021/Acs.Biochem.9B01072  0.305
2019 Haratipour P, Minard C, Nakhjiri M, Negahbani A, Kashemirov BA, McKenna CE. New Chirally Modified Bisphosphonates for Synthesis of Individual Beta,Gamma-CHX-Deoxynucleotide Diastereomers. Phosphorus, Sulfur, and Silicon and the Related Elements. 194: 329-330. PMID 32377060 DOI: 10.1080/10426507.2018.1540482  0.333
2019 Alnajjar KS, Krylov IS, Negahbani A, Haratipour P, Kashemirov BA, Huang J, Mahmoud M, McKenna CE, Goodman MF, Sweasy JB. A pre-catalytic non-covalent step governs DNA polymerase β fidelity. Nucleic Acids Research. PMID 31732732 DOI: 10.1093/Nar/Gkz1076  0.733
2019 Duro MVV, Alnajjar KS, Sweasy JB, Kashemirov BA, McKenna CE. Synthesis of -Formylphenylphosphonic Acids as Covalent Probes of Active Site Lysines. Phosphorus, Sulfur, and Silicon and the Related Elements. 194: 313-314. PMID 31213749 DOI: 10.1080/10426507.2018.1539996  0.372
2019 Oertell K, Florian J, Haratipour P, Crans DC, Kashemirov BA, Wilson SH, McKenna CE, Goodman MF. A Transition-State Perspective on Y-Family DNA Polymerase η Fidelity in Comparison with X-Family DNA Polymerases λ and β. Biochemistry. PMID 30839203 DOI: 10.1021/Acs.Biochem.9B00087  0.314
2018 Oertell K, Kashemirov BA, Negahbani A, Minard C, Haratipour P, Alnajjar KS, Sweasy JB, Batra VK, Beard WA, Wilson SH, McKenna CE, Goodman MF. Probing DNA base-dependent leaving group kinetic effects on the DNA polymerase transition state. Biochemistry. PMID 29889506 DOI: 10.1021/Acs.Biochem.8B00417  0.329
2018 Batra VK, Oertell K, Beard WA, Kashemirov BA, McKenna CE, Goodman MF, Wilson SH. Mapping functional substrate-enzyme interactions in the pol β active site through chemical biology: Structural responses to acidity modification of incoming dNTPs. Biochemistry. PMID 29874056 DOI: 10.1021/Acs.Biochem.8B00418  0.342
2017 Alnajjar KS, Negahbani A, Nakhjiri M, Krylov I, Kashemirov BA, McKenna CE, Goodman MF, Sweasy JB. DNA polymerase Beta Cancer-Associated Variant I260M Exhibits Nonspecific Selectivity Towards β-γ Bridging Group of the Incoming dNTP. Biochemistry. PMID 28862868 DOI: 10.1021/Acs.Biochem.7B00713  0.741
2017 Ni F, Kung A, Duan Y, Shah V, Amador C, Guo M, Fan X, Chen L, Chen Y, McKenna CE, Zhang C. Remarkably stereospecific utilization of ATP α,β-halomethylene analogues by protein kinases. Journal of the American Chemical Society. PMID 28535041 DOI: 10.1021/Jacs.7B03266  0.304
2017 Alnajjar KS, Garcia-Barboza B, Negahbani A, Nakhjiri M, Kashemirov BA, McKenna CE, Goodman MF, Sweasy JB. A Change in the Rate-Determining Step of Polymerization by the K289M DNA Polymerase Beta Cancer-Associated Variant. Biochemistry. PMID 28326765 DOI: 10.1021/Acs.Biochem.6B01230  0.301
2016 Hwang CS, Xu L, Wang W, Ulrich S, Zhang L, Chong J, Shin JH, Huang X, Kool ET, McKenna CE, Wang D. Functional interplay between NTP leaving group and base pair recognition during RNA polymerase II nucleotide incorporation revealed by methylene substitution. Nucleic Acids Research. PMID 27060150 DOI: 10.1093/Nar/Gkw220  0.514
2015 Hwang CS, Kung A, Kashemirov BA, Zhang C, McKenna CE. 5'-β,γ-CHF-ATP diastereomers: synthesis and fluorine-mediated selective binding by c-Src protein kinase. Organic Letters. 17: 1624-7. PMID 25781066 DOI: 10.1021/Ol503765N  0.31
2014 Oertell K, Chamberlain BT, Wu Y, Ferri E, Kashemirov BA, Beard WA, Wilson SH, McKenna CE, Goodman MF. Transition state in DNA polymerase β catalysis: rate-limiting chemistry altered by base-pair configuration. Biochemistry. 53: 1842-8. PMID 24580380 DOI: 10.1021/Bi500101Z  0.732
2013 Krylov IS, Kashemirov BA, Hilfinger JM, McKenna CE. Evolution of an amino acid based prodrug approach: stay tuned. Molecular Pharmaceutics. 10: 445-58. PMID 23339402 DOI: 10.1021/Mp300663J  0.75
2012 Wu Y, Zakharova VM, Kashemirov BA, Goodman MF, Batra VK, Wilson SH, McKenna CE. β,γ-CHF- and β,γ-CHCl-dGTP diastereomers: synthesis, discrete 31P NMR signatures, and absolute configurations of new stereochemical probes for DNA polymerases. Journal of the American Chemical Society. 134: 8734-7. PMID 22397499 DOI: 10.1021/Ja300218X  0.331
2012 Chamberlain BT, Batra VK, Beard WA, Kadina AP, Shock DD, Kashemirov BA, McKenna CE, Goodman MF, Wilson SH. Stereospecific formation of a ternary complex of (S)-α,β-fluoromethylene-dATP with DNA pol β. Chembiochem : a European Journal of Chemical Biology. 13: 528-30. PMID 22315190 DOI: 10.1002/Cbic.201100738  0.733
2012 Krylov IS, Zakharova VM, Serpi M, Haiges R, Kashemirov BA, McKenna CE. Structure of cyclic nucleoside phosphonate ester prodrugs: An inquiry Journal of Organic Chemistry. 77: 684-689. PMID 22126969 DOI: 10.1021/Jo201735F  0.727
2012 Chamberlain BT, Batra VK, Beard WA, Kadina AP, Shock DD, Kashemirov BA, McKenna CE, Goodman MF, Wilson SH. Stereospecific Formation of a Ternary Complex of (S)-alpha, beta-Fluoromethylene-dATP with DNA Pol beta. Chembiochem. 13: 528-530. DOI: 10.2210/Pdb3Tfr/Pdb  0.716
2011 B?a?ewska KM, Ni F, Haiges R, Kashemirov BA, Coxon FP, Stewart CA, Baron R, Rogers MJ, Seabra MC, Ebetino FH, McKenna CE. Synthesis, stereochemistry and SAR of a series of minodronate analogues as RGGT inhibitors. European Journal of Medicinal Chemistry. 46: 4820-6. PMID 21889236 DOI: 10.1016/J.Ejmech.2011.04.063  0.316
2011 Zakharova VM, Serpi M, Krylov IS, Peterson LW, Breitenbach JM, Borysko KZ, Drach JC, Collins M, Hilfinger JM, Kashemirov BA, McKenna CE. Tyrosine-based 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine and -adenine ((S)-HPMPC and (S)-HPMPA) prodrugs: synthesis, stability, antiviral activity, and in vivo transport studies. Journal of Medicinal Chemistry. 54: 5680-93. PMID 21812420 DOI: 10.1021/Jm2001426  0.777
2011 Peterson LW, Kim JS, Kijek P, Mitchell S, Hilfinger J, Breitenbach J, Borysko K, Drach JC, Kashemirov BA, McKenna CE. Synthesis, transport and antiviral activity of Ala-Ser and Val-Ser prodrugs of cidofovir. Bioorganic & Medicinal Chemistry Letters. 21: 4045-9. PMID 21641218 DOI: 10.1016/J.Bmcl.2011.04.126  0.638
2011 Chamberlain BT, Osuna J, Kashemirov BA, McKenna CE. Synthesis and sensing of bisphosphonophosphate alkyl monoesters: A novel class of compounds for the study of nucleoside 5'-triphosphate chemistry. Phosphorus, Sulfur, and Silicon and the Related Elements. 186: 966-967. PMID 21572560 DOI: 10.1080/10426507.2010.526675  0.78
2011 Zakharova VM, Krylov IS, Serpi M, Kashemirov BA, McKenna CE. Approaches to tyrosine-linked peptidomimetic prodrugs of (S)-HPMP-based acyclic nucleoside phosphonates. Phosphorus, Sulfur, and Silicon and the Related Elements. 186: 968-969. PMID 21566698 DOI: 10.1080/10426507.2010.526676  0.731
2011 Ebetino FH, Hogan AM, Sun S, Tsoumpra MK, Duan X, Triffitt JT, Kwaasi AA, Dunford JE, Barnett BL, Oppermann U, Lundy MW, Boyde A, Kashemirov BA, McKenna CE, Russell RG. The relationship between the chemistry and biological activity of the bisphosphonates. Bone. 49: 20-33. PMID 21497677 DOI: 10.1016/J.Bone.2011.03.774  0.323
2011 Chamberlain BT, Upton TG, Kashemirov BA, McKenna CE. α-Azido bisphosphonates: synthesis and nucleotide analogues. The Journal of Organic Chemistry. 76: 5132-6. PMID 21462930 DOI: 10.1021/Jo200045A  0.758
2011 Williams M, Krylov IS, Zakharova VM, Serpi M, Peterson LW, Krečmerová M, Kashemirov BA, McKenna CE. Cyclic and acyclic phosphonate tyrosine ester prodrugs of acyclic nucleoside phosphonates Collection of Czechoslovak Chemical Communications. 12: 167-170. DOI: 10.1135/Css201112167  0.779
2011 Gaidamauskas E, Crans DC, Parker H, Saejueng K, Kashemirov BA, McKenna CE. Quantification of foscarnet with chromogenic and fluorogenic chemosensors: Indicator displacement assays based on metal ion coordination with a catechol ligand moiety New Journal of Chemistry. 35: 2877-2883. DOI: 10.1039/C1Nj20460B  0.765
2011 Mustafa DA, Kashemirov BA, McKenna CE. Microwave-assisted synthesis of nitrogen-containing 1- hydroxymethylenebisphosphonate drugs Tetrahedron Letters. 52: 2285-2287. DOI: 10.1016/J.Tetlet.2011.02.058  0.552
2011 McKenna CE, Kashemirov BA, Zakharova VM, Krylov IS, Williams M, Krečmerová M, Drach JC, Hilfinger JM. Amido tyrosine esters: a promising new approach to antiviral nucleoside phosphonate prodrugs Antiviral Research. 90: A23-A24. DOI: 10.1016/J.Antiviral.2011.03.009  0.732
2010 Serpi M, Krylov IS, Zakharova VM, McKenna CE. Synthesis of peptidomimetic conjugates of cyclic nucleoside phosphonates. Current Protocols in Nucleic Acid Chemistry / Edited by Serge L. Beaucage ... [Et Al.]. Unit15.4. PMID 21154529 DOI: 10.1002/0471142700.Nc1504S43  0.755
2010 Peterson LW, Sala-Rabanal M, Krylov IS, Serpi M, Kashemirov BA, McKenna CE. Serine side chain-linked peptidomimetic conjugates of cyclic HPMPC and HPMPA: synthesis and interaction with hPEPT1. Molecular Pharmaceutics. 7: 2349-61. PMID 20929265 DOI: 10.1021/Mp100186B  0.772
2010 Surya Prakash GK, Zibinsky M, Upton TG, Kashemirov BA, McKenna CE, Oertell K, Goodman MF, Batra VK, Pedersen LC, Beard WA, Shock DD, Wilson SH, Olah GA. Synthesis and biological evaluation of fluorinated deoxynucleotide analogs based on bis-(difluoromethylene)triphosphoric acid. Proceedings of the National Academy of Sciences of the United States of America. 107: 15693-8. PMID 20724659 DOI: 10.1073/Pnas.1007430107  0.761
2010 Batra VK, Pedersen LC, Beard WA, Wilson SH, Kashemirov BA, Upton TG, Goodman MF, McKenna CE. Halogenated beta,gamma-methylene- and ethylidene-dGTP-DNA ternary complexes with DNA polymerase beta: structural evidence for stereospecific binding of the fluoromethylene analogues. Journal of the American Chemical Society. 132: 7617-25. PMID 20465217 DOI: 10.1021/Ja909370K  0.748
2010 Roelofs AJ, Coxon FP, Ebetino FH, Lundy MW, Henneman ZJ, Nancollas GH, Sun S, Blazewska KM, Bala JL, Kashemirov BA, Khalid AB, McKenna CE, Rogers MJ. Fluorescent risedronate analogues reveal bisphosphonate uptake by bone marrow monocytes and localization around osteocytes in vivo. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 25: 606-16. PMID 20422624 DOI: 10.1359/Jbmr.091009  0.746
2010 McKenna CE, Kashemirov BA, B?azewska KM, Mallard-Favier I, Stewart CA, Rojas J, Lundy MW, Ebetino FH, Baron RA, Dunford JE, Kirsten ML, Seabra MC, Bala JL, Marma MS, Rogers MJ, et al. Synthesis, chiral high performance liquid chromatographic resolution and enantiospecific activity of a potent new geranylgeranyl transferase inhibitor, 2-hydroxy-3-imidazo[1,2-a]pyridin-3-yl-2-phosphonopropionic acid. Journal of Medicinal Chemistry. 53: 3454-64. PMID 20394422 DOI: 10.1021/Jm900232U  0.779
2010 McKenna CE, Kashemirov BA, Peterson LW, Goodman MF. Modifications to the dNTP triphosphate moiety: from mechanistic probes for DNA polymerases to antiviral and anti-cancer drug design. Biochimica Et Biophysica Acta. 1804: 1223-30. PMID 20079885 DOI: 10.1016/J.Bbapap.2010.01.005  0.643
2010 Pan JJ, Kashemirov BA, Lee J, McKenna CE, Devlin FJ, Stephens PJ. Electronic circular dichroism of monomethyl [16O,17O,18O]-phosphate and [16O,17O,18O]-thiophosphate revisited. Bioorganic Chemistry. 38: 7-16. PMID 20018339 DOI: 10.1016/J.Bioorg.2009.02.001  0.601
2010 Tehler U, Nelson CH, Peterson LW, Provoda CJ, Hilfinger JM, Lee KD, McKenna CE, Amidon GL. Puromycin-sensitive aminopeptidase: an antiviral prodrug activating enzyme. Antiviral Research. 85: 482-9. PMID 19969024 DOI: 10.1016/J.Antiviral.2009.12.003  0.644
2010 Bala JLF, Kashemirov BA, McKenna CE. Synthesis of a novel bisphosphonic acid alkene monomer Synthetic Communications. 40: 3577-3584. DOI: 10.1080/00397910903531706  0.312
2010 Zhang H, Pang W, Marma MS, Lee CY, Kamal-Bahl S, Kim ES, McKenna CE. Label-free detection of protein-ligand interactions in real time using micromachined bulk acoustic resonators Applied Physics Letters. 96. DOI: 10.1063/1.3358118  0.746
2009 Gaidamauskas E, Parker H, Kashemirov BA, Holder AA, Saejueng K, McKenna CE, Crans DC. Complexation of bisphosphonates with ytterbium(III): application of phosphate and ATP detection assay based on Yb(3+)-pyrocatechol violet. Journal of Inorganic Biochemistry. 103: 1652-7. PMID 19850352 DOI: 10.1016/J.Jinorgbio.2009.09.006  0.775
2009 Kamerlin SC, McKenna CE, Goodman MF, Goondman MF, Warshel A. A computational study of the hydrolysis of dGTP analogues with halomethylene-modified leaving groups in solution: implications for the mechanism of DNA polymerases. Biochemistry. 48: 5963-71. PMID 19391628 DOI: 10.1021/Bi900140C  0.327
2009 Peterson LW, McKenna CE. Prodrug approaches to improving the oral absorption of antiviral nucleotide analogues. Expert Opinion On Drug Delivery. 6: 405-20. PMID 19382883 DOI: 10.1517/17425240902824808  0.633
2009 Upton TG, Kashemirov BA, McKenna CE, Goodman MF, Prakash GK, Kultyshev R, Batra VK, Shock DD, Pedersen LC, Beard WA, Wilson SH. Alpha,beta-difluoromethylene deoxynucleoside 5'-triphosphates: a convenient synthesis of useful probes for DNA polymerase beta structure and function. Organic Letters. 11: 1883-6. PMID 19351147 DOI: 10.1021/Ol701755K  0.729
2009 Baron RA, Tavaré R, Figueiredo AC, B?azewska KM, Kashemirov BA, McKenna CE, Ebetino FH, Taylor A, Rogers MJ, Coxon FP, Seabra MC. Phosphonocarboxylates inhibit the second geranylgeranyl addition by Rab geranylgeranyl transferase. The Journal of Biological Chemistry. 284: 6861-8. PMID 19074143 DOI: 10.1074/Jbc.M806952200  0.305
2009 Boyde A, Lundy M, Coxon F, McKenna C, Roelofs A, Bala J, Rogers M, Blazewska K, Russell R, Ebetino F. The differential distribution in vivo of fluorescently-labeled bisphosphonate analogues with different mineral affinity to bone surfaces Bone. 44: S57. DOI: 10.1016/J.Bone.2009.01.016  0.739
2009 McKenna CE, Peterson LW, Kashemirov BA, Serpi M, Mitchell S, Kim JS, Hilfinger JM, Drach JC. New peptidomimetic prodrugs of acyclic and cyclic cidofovir: sar studies of chemical and enzymatic activation mechanisms Antiviral Research. 82: A75. DOI: 10.1016/J.Antiviral.2009.02.206  0.626
2009 Krylov IS, Peterson LW, Kashemirov BA, Breitenbach J, Borysco K, Drach JC, Kim JS, Hilfinger JM, McKenna CE. In vitro transport, activation and antiviral evaluation of new HPMPA prodrugs synthesized on a solid support Antiviral Research. 82: A75. DOI: 10.1016/J.Antiviral.2009.02.205  0.766
2009 Sala-Rabanal M, Peterson LW, Serpi M, Krylov IS, Kashemirov BA, Kim JS, Mitchell S, Hilfinger JM, McKenna CE. Interactions Between the Human Oligopeptide Transporter, hPepT1 and Serine Side-chain-linked Cidofovir Prodrugs Antiviral Research. 82: A53-A54. DOI: 10.1016/J.Antiviral.2009.02.124  0.754
2008 Kashemirov BA, Bala JL, Chen X, Ebetino FH, Xia Z, Russell RG, Coxon FP, Roelofs AJ, Rogers MJ, McKenna CE. Fluorescently labeled risedronate and related analogues: "magic linker" synthesis. Bioconjugate Chemistry. 19: 2308-10. PMID 19032080 DOI: 10.1021/Bc800369C  0.752
2008 Gaidamauskas E, Saejueng K, Holder AA, Bharuah S, Kashemirov BA, Crans DC, McKenna CE. Metal complexation chemistry used for phosphate and nucleotide determination: an investigation of the Yb3+-pyrocatechol violet sensor. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 13: 1291-9. PMID 18704521 DOI: 10.1007/S00775-008-0415-2  0.771
2008 Eriksson U, Peterson LW, Kashemirov BA, Hilfinger JM, Drach JC, Borysko KZ, Breitenbach JM, Kim JS, Mitchell S, Kijek P, McKenna CE. Serine peptide phosphoester prodrugs of cyclic cidofovir: synthesis, transport, and antiviral activity. Molecular Pharmaceutics. 5: 598-609. PMID 18481868 DOI: 10.1021/Mp8000099  0.715
2008 Deprèle S, Kashemirov BA, Hogan JM, Ebetino FH, Barnett BL, Evdokimov A, McKenna CE. Farnesyl pyrophosphate synthase enantiospecificity with a chiral risedronate analog, [6,7-dihydro-5H-cyclopenta[c]pyridin-7-yl(hydroxy)methylene]bis(phosphonic acid) (NE-10501): Synthetic, structural, and modeling studies. Bioorganic & Medicinal Chemistry Letters. 18: 2878-82. PMID 18434151 DOI: 10.1016/J.Bmcl.2008.03.088  0.347
2008 Sucato CA, Upton TG, Kashemirov BA, Osuna J, Oertell K, Beard WA, Wilson SH, Florián J, Warshel A, McKenna CE, Goodman MF. DNA polymerase beta fidelity: halomethylene-modified leaving groups in pre-steady-state kinetic analysis reveal differences at the chemical transition state. Biochemistry. 47: 870-9. PMID 18161950 DOI: 10.1021/Bi7014162  0.781
2008 Alfonsov VA, McKenna CE, Bayandina EV, Kashemirov B, Yarmieva LN, Kataeva ON, Punegova LN. Diastereoselective synthesis of enantiopure cyclic α-aminophosphonic acids Phosphorus, Sulfur and Silicon and the Related Elements. 183: 2647-2648. DOI: 10.1080/10426500802344568  0.31
2008 Stewart CA, Baron R, Marma MS, Blazewska KM, Kashemirov BA, Ebetino FH, McKenna CE, Rogers MJ, Coxon FP. Structure activity relationships of phosphonocarboxylate inhibitors of rab geranylgeranyl transferase Bone. 42: S86-S87. DOI: 10.1016/J.Bone.2007.12.163  0.743
2008 Coxon FP, Bala JL, Kashemirov BA, Lundy MW, Chen X, Xia Z, Dunford JE, Russell GG, Roelofs AJ, Rogers MJ, McKenna CE, Ebetino FH. Fluorescently labeled risedronate and related analogs: Design and evaluation as imaging probes Bone. 42: S36. DOI: 10.1016/J.Bone.2007.12.054  0.733
2008 Pham CV, Kashemirov BA, Osuna J, Saejueng K, Hilfinger JM, McKenna CE. Synthesis of P–O–C-linked Foscarnet–Peptide Conjugates and Sensitive Methods to Detect the Released Drug in Biological Samples Antiviral Research. 78: A62. DOI: 10.1016/J.Antiviral.2008.01.133  0.753
2008 Peterson LW, Kashemirov BA, Eriksson U, Kim J, Mitchell S, Kijek P, Lee K, Hilfinger JM, McKenna CE. Serine Side-Chain-linked Peptidomimetic Prodrugs of Cidofovir and Cyclic Cidofovir: C-Ester Effects on Transport and Activation Antiviral Research. 78: A46. DOI: 10.1016/J.Antiviral.2008.01.091  0.707
2008 Alfonsov VA, McKenna CE, Bayandina EV, Kashemirov BA, Yarmieva LN, Punegova LN, Kataeva ON. Stereoselective synthesis of enantiopure cyclic α-aminophosphonic acids: Direct observation of inversion at phosphorus in phosphonate ester silyldealkylation by bromotrimethylsilane Heteroatom Chemistry. 19: 575-582. DOI: 10.1002/Hc.20480  0.318
2007 McKenna CE, Kashemirov BA, Upton TG, Batra VK, Goodman MF, Pedersen LC, Beard WA, Wilson SH. (R)-beta,gamma-fluoromethylene-dGTP-DNA ternary complex with DNA polymerase beta. Journal of the American Chemical Society. 129: 15412-3. PMID 18031037 DOI: 10.1021/Ja072127V  0.757
2007 Marma MS, Xia Z, Stewart C, Coxon F, Dunford JE, Baron R, Kashemirov BA, Ebetino FH, Triffitt JT, Russell RG, McKenna CE. Synthesis and biological evaluation of alpha-halogenated bisphosphonate and phosphonocarboxylate analogues of risedronate. Journal of Medicinal Chemistry. 50: 5967-75. PMID 17975902 DOI: 10.1021/Jm0702884  0.749
2007 Zhang H, Marma MS, Kim ES, McKenna CE, Thompson ME. Mercuric ion sensing by a film bulk acoustic resonator. Ieee Transactions On Ultrasonics, Ferroelectrics, and Frequency Control. 54: 1723-5. PMID 17941378 DOI: 10.1109/Tuffc.2007.456  0.74
2007 Sucato CA, Upton TG, Kashemirov BA, Batra VK, Martínek V, Xiang Y, Beard WA, Pedersen LC, Wilson SH, McKenna CE, Florián J, Warshel A, Goodman MF. Modifying the beta,gamma leaving-group bridging oxygen alters nucleotide incorporation efficiency, fidelity, and the catalytic mechanism of DNA polymerase beta. Biochemistry. 46: 461-71. PMID 17209556 DOI: 10.1021/Bi061517B  0.751
2007 Eriksson U, Hilfinger JM, Kim JS, Mitchell S, Kijek P, Borysko KZ, Breitenbach JM, Drach JC, Kashemirov BA, McKenna CE. Synthesis and biological activation of an ethylene glycol-linked amino acid conjugate of cyclic cidofovir. Bioorganic & Medicinal Chemistry Letters. 17: 583-6. PMID 17161946 DOI: 10.1016/J.Bmcl.2006.11.012  0.566
2007 Zhang H, Marma MS, Bahl SK, Kim ES, McKenna CE. Sequence specific label-free DNA sensing using film-bulk-acoustic- resonators Ieee Sensors Journal. 7: 1587-1588. DOI: 10.1109/Jsen.2007.905035  0.746
2007 PETERSON L, KASHEMIROV B, BLAZEWSKA K, BREITENBACK J, BORYSKO K, DRACH J, KIM J, KIJEK P, HILFINGER J, MCKENNA C. Synthesis and Structure–Activity Aspects of Some Cyclic Cidofovir Peptidomimetic Prodrugs Antiviral Research. 74: A33-A33. DOI: 10.1016/J.Antiviral.2007.01.023  0.626
2006 Xia Z, Lawson M, Triffitt J, Ebetino F, McKenna C, Marma M, Kashimirov B, Russell R. Substitution of the R1 hydroxyl and C1 phosphate of risedronate produces differences in elution profiles on hydroxyapatite ceramic chromatographic columns Bone. 38: 63-64. DOI: 10.1016/J.Bone.2005.12.076  0.737
2006 Coxon F, Navea JR, Stewart C, Thompson K, Roelofs A, Ebetino F, McKenna C, Kashemirov B, Bala J, Rogers M. Target enzyme specificity, potency and potential lack of side-effects of novel phosphonocarboxylate analogues of bisphosphonates Bone. 38: 46-47. DOI: 10.1016/J.Bone.2005.12.034  0.742
2005 Zhang H, Marma MS, Kim ES, McKenna CE, Thompson ME. Mercury ion sensing by film-bulk-acoustic-resonator mass sensor Proceedings of Ieee Sensors. 2005: 203-206. DOI: 10.1109/ICSENS.2005.1597671  0.72
2005 Zhang H, Marma MS, Kim ES, McKenna CE, Thompson ME. A film bulk acoustic resonator in liquid environments Journal of Micromechanics and Microengineering. 15: 1911-1916. DOI: 10.1088/0960-1317/15/10/017  0.736
2005 McKenna CE, Kashemirov BA, Eriksson U, Amidon GL, Kish PE, Mitchell S, Kim JS, Hilfinger JM. Cidofovir peptide conjugates as prodrugs Journal of Organometallic Chemistry. 690: 2673-2678. DOI: 10.1016/j.jorganchem.2005.03.004  0.428
2005 Kunikeev SD, Taylor HS, Pan JJ, Kershaw A, McKenna CE. A new signal processing method to observe weak 31P and 17O NMR peaks Journal of Organometallic Chemistry. 690: 2644-2650. DOI: 10.1016/J.Jorganchem.2004.10.015  0.495
2005 Marma MS, Khawli LA, Harutunian V, Kashemirov BA, McKenna CE. Synthesis of α-fluorinated phosphonoacetate derivatives using electrophilic fluorine reagents: Perchloryl fluoride versus 1-chloromethyl-4- fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(tetrafluoroborate) (Selectfluor®) Journal of Fluorine Chemistry. 126: 1467-1475. DOI: 10.1016/J.Jfluchem.2005.04.002  0.77
2004 Marma MS, Kashemirov BA, McKenna CE. Synthesis and stability studies of phosphonoformate-amino acid conjugates: a new class of slowly releasing foscarnet prodrugs. Bioorganic & Medicinal Chemistry Letters. 14: 1787-90. PMID 15026072 DOI: 10.1016/J.Bmcl.2004.01.016  0.767
2004 Zhang H, Marma MS, Kim ES, McKenna CE, Thompson ME. Implantable resonant mass sensor for liquid biochemical sensing Proceedings of the Ieee International Conference On Micro Electro Mechanical Systems (Mems). 347-350.  0.717
2002 McKenna CE, Kashemirov BA, Rozé CN. Carbonylbisphosphonate and (diazomethylene)bisphosphonate analogues of AZT 5(')-diphosphate. Bioorganic Chemistry. 30: 383-95. PMID 12642124 DOI: 10.1016/S0045-2068(02)00521-7  0.342
2002 Ju J, McKenna CE. Synthesis of oligodeoxyribonucleoside phosphorothioates using Lawesson's reagent for the sulfur transfer step. Bioorganic & Medicinal Chemistry Letters. 12: 1643-5. PMID 12039581 DOI: 10.1016/S0960-894X(02)00233-0  0.546
2002 Kashemirov BA, Rozé CN, McKenna CE. Carbonylbisphosphonate analogues of nucleoside 5′-diphosphates Phosphorus, Sulfur and Silicon and Related Elements. 177: 2275. DOI: 10.1080/10426500214129  0.309
2002 Kashemirov BA, Carrick JM, Bau R, McKenna CE. Troika acid derivatives: Multifunctional ligands for metal complexation in solution and on solid supports. A novel, linear trinickel ("troitsa") complex Phosphorus, Sulfur and Silicon and Related Elements. 177: 2273. DOI: 10.1080/10426500214110  0.765
2000 Carrick JM, Kashemirov BA, McKenna CE. Indirect photo-induced phosphorylation via a photolabile troika acid C- ester: O-nitrobenzyl (E)-(hydroxyimino)(dihydroxyphosphinyl)acetate Tetrahedron. 56: 2391-2396. DOI: 10.1016/S0040-4020(00)00138-1  0.764
1999 Krause SO, Gutheil WG, Simeonov AM, Matsunaga TO, Stauber MJ, Kenyon GL, Mckenna CE. Perspectives on the mechanism of ATP hydrolysis by nitrogenase Phosphorus, Sulfur and Silicon and Related Elements. 144: 513-516. DOI: 10.1080/10426509908546294  0.695
1999 Liu X, Li Z, McKenna CE. The Preparation of Sulfur-Containing Phosphonoformate Derivatives Phosphorus, Sulfur, and Silicon and the Related Elements. 147: 213-213. DOI: 10.1080/10426509908053587  0.31
1999 Carrick JM, Kashemirov BA, McKenna CE. Indirect Photo-Induced Phosphorylation Via a C-Ester Caged Troika Acid Phosphorus, Sulfur, and Silicon and the Related Elements. 147: 65-65. DOI: 10.1080/10426509908053513  0.77
1996 McKenna C, Kashemirov B, Fujimolo M. (Hydroxyimino)Phosphonoacetic Acids: Synthesis, Stereochemistry and Reactivity Phosphorus, Sulfur, and Silicon and the Related Elements. 111: 158-158. DOI: 10.1080/10426509608054787  0.318
1995 Peng ZY, Mansour JM, Araujo F, Ju JY, McKenna CE, Mansour TE. Some phosphonic acid analogs as inhibitors of pyrophosphate-dependent phosphofructokinase, a novel target in Toxoplasma gondii. Biochemical Pharmacology. 49: 105-13. PMID 7840776 DOI: 10.1016/0006-2952(94)00437-Q  0.576
1992 Gutheil WG, McKenna CE. Unique and independent parameters (UIP) formulation for thermodynamic models of complex protein-ligand systems. Biophysical Chemistry. 45: 171-9. PMID 1286150 DOI: 10.1016/0301-4622(92)87009-8  0.633
1991 McKenna CE, Gutheil WG, Song W. A method for preparing analytically pure sodium dithionite. Dithionite quality and observed nitrogenase-specific activities. Biochimica Et Biophysica Acta. 1075: 109-17. PMID 1892862 DOI: 10.1016/0304-4165(91)90082-R  0.633
1990 Mckenna CE, Ye T-, Levy JN, Pham P, Wen T, Bongartz J-, Starnes MC, Cheng Y-. Design and Synthesis of Organophosphorus Compounds with Antiviral and Other Bioactivities Phosphorus Sulfur and Silicon and the Related Elements. 183-186. DOI: 10.1080/10426509008038936  0.321
1989 McKenna CE, Gutheil WG, Kenyon GL, Matsunaga TO. Mass spectrometric analysis of phosphate from β,γ-[18O]ATP hydrolyzed by Azotobacter vinelandii nitrogenase: Direct evidence for PγOPβ bond cleavage Bioorganic Chemistry. 17: 377-384. DOI: 10.1016/0045-2068(89)90039-4  0.718
1981 Stephens PJ, McKenna CE, McKenna MC, Nguyen HT, Devlin F. Circular dichroism and magnetic circular dichroism of reduced molybdenum-iron protein of Azotobacter vinelandii nitrogenase. Biochemistry. 20: 2857-64. PMID 6941811 DOI: 10.1021/Bi00513A023  0.431
1979 McKenna CE, Huang CW. In vivo reduction of cyclopropane by Azotobacter vinelandii nitrogenase [23] Nature. 280: 609-611. DOI: 10.1038/280609A0  0.3
1979 McKenna CE, Schmidhuser J. Functional selectivity in phosphonate ester dealkylation with bromotrimethylsilane Journal of the Chemical Society, Chemical Communications. 739. DOI: 10.1002/Chin.198002274  0.306
1977 GOLDSTEIN JA, MCKENNA C, WESTHEIMER FH. ChemInform Abstract: α-DIAZOBENZYLPHOSPHONATE DIANIONS Chemischer Informationsdienst. 8: no-no. DOI: 10.1002/Chin.197706222  0.498
1976 Goldstein JA, McKenna C, Westheimer FH. .alpha.-Diazobenzylphosphonate dianions Journal of the American Chemical Society. 98: 7327-7332. DOI: 10.1021/Ja00439A037  0.48
1972 Benemann JR, McKenna CE, Lie RF, Traylor TG, Kamen MD. The vanadium effect in nitrogen fixation by azotobacter. Biochimica Et Biophysica Acta. 264: 25-38. PMID 5021990 DOI: 10.1016/0304-4165(72)90113-4  0.501
1971 MCKENNA CE, TRAYLOR TG. ChemInform Abstract: DIREKTE BEOBACHTUNG VON DIAZEN-ZWISCHENSTUFEN BEI DER BORHYDRID-RED. VON DIAZONIUMSALZEN, NEUER WEG ZU ARYLDIAZENEN Chemischer Informationsdienst. Organische Chemie. 2: no-no. DOI: 10.1002/Chin.197130220  0.484
1971 McKenna CE, Traylor TG. Direct observation of diazene intermediates in borohydride reduction of diazonium salts. A new route to aryldiazenes [4] Journal of the American Chemical Society. 93: 2313-2314.  0.451
1970 McKenna CE, Benemann JR, Traylor TG. A vanadium containing nitrogenase preparation: implications for the role of molybdenum in nitrogen fixation. Biochemical and Biophysical Research Communications. 41: 1501-8. PMID 5487874 DOI: 10.1016/0006-291X(70)90557-7  0.521
1967 Hanstein WG, Lett JB, McKenna CE, Traylor TG. Heme protein-diimide complex- es: possible intermediates in biological nitrogen fixation. Proceedings of the National Academy of Sciences of the United States of America. 58: 1314-6. PMID 5238804 DOI: 10.1073/Pnas.58.4.1314  0.442
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