Thanashan Rajakulendran, Ph.D. - Publications
Affiliations: | 2011 | Molecular and Medical Genetics | University of Toronto, Toronto, ON, Canada |
Area:
protein kinase regulationYear | Citation | Score | |||
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2016 | Spencer-Smith R, Koide A, Zhou Y, Eguchi RR, Sha F, Gajwani P, Santana D, Gupta A, Jacobs M, Herrero-Garcia E, Cobbert J, Lavoie H, Smith M, Rajakulendran T, Dowdell E, et al. Inhibition of RAS function through targeting an allosteric regulatory site. Nature Chemical Biology. PMID 27820802 DOI: 10.1038/Nchembio.2231 | 0.465 | |||
2014 | Rajakulendran T, Adam DN. Bench to bedside: mechanistic principles of targeting the RAF kinase in melanoma. International Journal of Dermatology. 53: 1428-33. PMID 25311997 DOI: 10.1111/Ijd.12724 | 0.465 | |||
2011 | Udell CM, Rajakulendran T, Sicheri F, Therrien M. Mechanistic principles of RAF kinase signaling. Cellular and Molecular Life Sciences : Cmls. 68: 553-65. PMID 20820846 DOI: 10.1007/S00018-010-0520-6 | 0.636 | |||
2010 | Rajakulendran T, Sicheri F. Allosteric Protein kinase regulation by pseudokinases: Insights from STRAD Science Signaling. 3: pe8. PMID 20197543 DOI: 10.1126/Scisignal.3111Pe8 | 0.596 | |||
2009 | Rajakulendran T, Sahmi M, Lefrançois M, Sicheri F, Therrien M. A dimerization-dependent mechanism drives RAF catalytic activation. Nature. 461: 542-5. PMID 19727074 DOI: 10.1038/Nature08314 | 0.633 | |||
2008 | Rajakulendran T, Sahmi M, Kurinov I, Tyers M, Therrien M, Sicheri F. CNK and HYP form a discrete dimer by their SAM domains to mediate RAF kinase signaling. Proceedings of the National Academy of Sciences of the United States of America. 105: 2836-41. PMID 18287031 DOI: 10.1073/Pnas.0709705105 | 0.604 | |||
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