Year |
Citation |
Score |
2021 |
Ningoo M, Plant LD, Greka A, Logothetis DE. PIP regulation of TRPC5 channel activation and desensitization. The Journal of Biological Chemistry. 100726. PMID 33933453 DOI: 10.1016/j.jbc.2021.100726 |
0.585 |
|
2019 |
Pablo JL, Greka A. Charting a TRP to Novel Therapeutic Destinations for Kidney Diseases. Trends in Pharmacological Sciences. PMID 31704171 DOI: 10.1016/J.Tips.2019.10.001 |
0.424 |
|
2019 |
Dvela-Levitt M, Kost-Alimova M, Emani M, Kohnert E, Thompson R, Sidhom EH, Rivadeneira A, Sahakian N, Roignot J, Papagregoriou G, Montesinos MS, Clark AR, McKinney D, Gutierrez J, Roth M, ... ... Greka A, et al. Small Molecule Targets TMED9 and Promotes Lysosomal Degradation to Reverse Proteinopathy. Cell. 178: 521-535.e23. PMID 31348885 DOI: 10.1016/J.Cell.2019.07.002 |
0.367 |
|
2019 |
Sharma SH, Pablo JL, Montesinos MS, Greka A, Hopkins CR. Design, synthesis and characterization of novel N-heterocyclic-1-benzyl-1H-benzo[d]imidazole-2-amines as selective TRPC5 inhibitors leading to the identification of the selective compound, AC1903. Bioorganic & Medicinal Chemistry Letters. 29: 155-159. PMID 30538066 DOI: 10.1016/J.Bmcl.2018.12.007 |
0.321 |
|
2018 |
Wang L, Fu TM, Zhou Y, Xia S, Greka A, Wu H. Structures and gating mechanism of human TRPM2. Science (New York, N.Y.). PMID 30467180 DOI: 10.1126/Science.Aav4809 |
0.416 |
|
2018 |
Christov M, Clark AR, Corbin B, Hakroush S, Rhee EP, Saito H, Brooks D, Hesse E, Bouxsein M, Galjart N, Jung JY, Mundel P, Jüppner H, Weins A, Greka A. Inducible podocyte-specific deletion of CTCF drives progressive kidney disease and bone abnormalities. Jci Insight. 3. PMID 29467330 DOI: 10.1172/Jci.Insight.95091 |
0.301 |
|
2017 |
Sieber J, Wieder N, Clark A, Reitberger M, Matan S, Schoenfelder J, Zhang J, Mandinova A, Bittker JA, Gutierrez J, Aygün O, Udeshi N, Carr S, Mundel P, Jehle AW, ... Greka A, et al. GDC-0879, a BRAFV600E Inhibitor, Protects Kidney Podocytes from Death. Cell Chemical Biology. PMID 29249695 DOI: 10.1016/J.Chembiol.2017.11.006 |
0.317 |
|
2017 |
Zhou Y, Castonguay P, Sidhom EH, Clark AR, Dvela-Levitt M, Kim S, Sieber J, Wieder N, Jung JY, Andreeva S, Reichardt J, Dubois F, Hoffmann SC, Basgen JM, Montesinos MS, ... ... Greka A, et al. A small-molecule inhibitor of TRPC5 ion channels suppresses progressive kidney disease in animal models. Science (New York, N.Y.). 358: 1332-1336. PMID 29217578 DOI: 10.1126/Science.Aal4178 |
0.399 |
|
2016 |
Buvall L, Wallentin H, Sieber J, Andreeva S, Choi HY, Mundel P, Greka A. Synaptopodin Is a Coincidence Detector of Tyrosine versus Serine/Threonine Phosphorylation for the Modulation of Rho Protein Crosstalk in Podocytes. Journal of the American Society of Nephrology : Jasn. PMID 27628902 DOI: 10.1681/Asn.2016040414 |
0.343 |
|
2016 |
Zhou Y, Greka A. Calcium Signaling in the Kidney. American Journal of Physiology. Renal Physiology. ajprenal.00117.2016. PMID 27029425 DOI: 10.1152/Ajprenal.00117.2016 |
0.342 |
|
2016 |
Greka A. Human genetics of nephrotic syndrome and the quest for precision medicine. Current Opinion in Nephrology and Hypertension. PMID 26808706 DOI: 10.1097/Mnh.0000000000000204 |
0.36 |
|
2015 |
Wieder N, Greka A. Calcium, TRPC channels, and regulation of the actin cytoskeleton in podocytes: towards a future of targeted therapies. Pediatric Nephrology (Berlin, Germany). PMID 26490951 DOI: 10.1007/S00467-015-3224-1 |
0.413 |
|
2013 |
Buvall L, Rashmi P, Lopez-Rivera E, Andreeva S, Weins A, Wallentin H, Greka A, Mundel P. Proteasomal degradation of Nck1 but not Nck2 regulates RhoA activation and actin dynamics. Nature Communications. 4: 2863. PMID 24287595 DOI: 10.1038/Ncomms3863 |
0.326 |
|
2013 |
Schaldecker T, Kim S, Tarabanis C, Tian D, Hakroush S, Castonguay P, Ahn W, Wallentin H, Heid H, Hopkins CR, Lindsley CW, Riccio A, Buvall L, Weins A, Greka A. Inhibition of the TRPC5 ion channel protects the kidney filter. The Journal of Clinical Investigation. 123: 5298-309. PMID 24231357 DOI: 10.1172/Jci71165 |
0.417 |
|
2012 |
Carrasquillo R, Tian D, Krishna S, Pollak MR, Greka A, Schlöndorff J. SNF8, a member of the ESCRT-II complex, interacts with TRPC6 and enhances its channel activity. Bmc Cell Biology. 13: 33. PMID 23171048 DOI: 10.1186/1471-2121-13-33 |
0.434 |
|
2012 |
Greka A, Mundel P. Calcium regulates podocyte actin dynamics. Seminars in Nephrology. 32: 319-26. PMID 22958486 DOI: 10.1016/J.Semnephrol.2012.06.003 |
0.344 |
|
2012 |
Greka A, Mundel P. Cell biology and pathology of podocytes. Annual Review of Physiology. 74: 299-323. PMID 22054238 DOI: 10.1146/Annurev-Physiol-020911-153238 |
0.36 |
|
2011 |
Greka A, Mundel P. Balancing calcium signals through TRPC5 and TRPC6 in podocytes. Journal of the American Society of Nephrology : Jasn. 22: 1969-80. PMID 21980113 DOI: 10.1681/Asn.2011040370 |
0.406 |
|
2010 |
Tian D, Jacobo SM, Billing D, Rozkalne A, Gage SD, Anagnostou T, Pavenstädt H, Pavenstaedt H, Hsu HH, Schlondorff J, Ramos A, Greka A. Antagonistic regulation of actin dynamics and cell motility by TRPC5 and TRPC6 channels. Science Signaling. 3: ra77. PMID 20978238 DOI: 10.1126/Scisignal.2001200 |
0.419 |
|
2007 |
Möller CC, Wei C, Altintas MM, Li J, Greka A, Ohse T, Pippin JW, Rastaldi MP, Wawersik S, Schiavi S, Henger A, Kretzler M, Shankland SJ, Reiser J. Induction of TRPC6 channel in acquired forms of proteinuric kidney disease. Journal of the American Society of Nephrology : Jasn. 18: 29-36. PMID 17167110 DOI: 10.1681/Asn.2006091010 |
0.451 |
|
2005 |
Moore JE, Runnels LW, Greka A, Navarro B, Clapham DE. 225 THE CALCIUM-PERMEABLE ION CHANNEL TRPM7 MAY PLAY A ROLE IN CELL MOTILITY AND WOUND REPAIR IN RAT CARDIAC FIBROBASTS Journal of Investigative Medicine. 53: S292.4-S292. DOI: 10.2310/6650.2005.00006.224 |
0.445 |
|
2004 |
Bezzerides VJ, Ramsey IS, Kotecha S, Greka A, Clapham DE. Rapid vesicular translocation and insertion of TRP channels. Nature Cell Biology. 6: 709-20. PMID 15258588 DOI: 10.1038/Ncb1150 |
0.69 |
|
2003 |
Greka A, Navarro B, Oancea E, Duggan A, Clapham DE. TRPC5 is a regulator of hippocampal neurite length and growth cone morphology. Nature Neuroscience. 6: 837-45. PMID 12858178 DOI: 10.1038/Nn1092 |
0.67 |
|
2003 |
Oancea E, Bezzerides VJ, Greka A, Clapham DE. Mechanism of persistent protein kinase D1 translocation and activation. Developmental Cell. 4: 561-74. PMID 12689594 DOI: 10.1016/S1534-5807(03)00087-X |
0.645 |
|
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