| Year |
Citation |
Score |
| 2024 |
Wessendorf-Rodriguez K, Ruchhoeft ML, Ashley EL, Galvez HM, Murray CW, McGregor G, Kambhampati S, Shaw RJ, Metallo CM. Modeling compound lipid homeostasis using stable isotope tracing. Biorxiv : the Preprint Server For Biology. PMID 39463985 DOI: 10.1101/2024.10.16.618599 |
0.316 |
|
| 2024 |
Christofk H, Metallo C, Liu G, Rabinowitz J, Sparks L, James D. Metabolic heterogeneity in humans. Cell. 187: 3821-3823. PMID 39059358 DOI: 10.1016/j.cell.2024.06.033 |
0.314 |
|
| 2024 |
Lim EW, Metallo CM. Tracing the Diverse Paths of One-Carbon Metabolism in Cancer and Beyond. Cold Spring Harbor Perspectives in Medicine. PMID 38503499 DOI: 10.1101/cshperspect.a041533 |
0.304 |
|
| 2023 |
Muta Y, Linares JF, Martinez-Ordoñez A, Duran A, Cid-Diaz T, Kinoshita H, Zhang X, Han Q, Nakanishi Y, Nakanishi N, Cordes T, Arora GK, Ruiz-Martinez M, Reina-Campos M, Kasashima H, ... ... Metallo CM, et al. Enhanced SREBP2-driven cholesterol biosynthesis by PKCλ/ι deficiency in intestinal epithelial cells promotes aggressive serrated tumorigenesis. Nature Communications. 14: 8075. PMID 38092754 DOI: 10.1038/s41467-023-43690-5 |
0.309 |
|
| 2023 |
Zhang J, Keibler MA, Dong W, Ghelfi J, Cordes T, Kanashova T, Pailot A, Linster CL, Dittmar G, Metallo CM, Lautenschlaeger T, Hiller K, Stephanopoulos G. Stable Isotope-Assisted Untargeted Metabolomics Identifies ALDH1A1-Driven Erythronate Accumulation in Lung Cancer Cells. Biomedicines. 11. PMID 37893215 DOI: 10.3390/biomedicines11102842 |
0.321 |
|
| 2023 |
Kuna RS, Kumar A, Wessendorf-Rodriguez KA, Galvez H, Green CR, McGregor GH, Cordes T, Shaw RJ, Svensson RU, Metallo CM. Inter-organelle cross-talk supports acetyl-coenzyme A homeostasis and lipogenesis under metabolic stress. Science Advances. 9: eadf0138. PMID 37134162 DOI: 10.1126/sciadv.adf0138 |
0.357 |
|
| 2022 |
Cordes T, Kuna RS, McGregor GH, Khare SV, Gengatharan J, Muthusamy T, Metallo CM. 1-Deoxysphingolipid synthesis compromises anchorage-independent growth and plasma membrane endocytosis in cancer cells. Journal of Lipid Research. 63: 100281. PMID 36115594 DOI: 10.1016/j.jlr.2022.100281 |
0.336 |
|
| 2021 |
Kumar A, Cordes T, Thalacker-Mercer AE, Pajor AM, Murphy AN, Metallo CM. NaCT/SLC13A5 facilitates citrate import and metabolism under nutrient-limited conditions. Cell Reports. 36: 109701. PMID 34525352 DOI: 10.1016/j.celrep.2021.109701 |
0.346 |
|
| 2021 |
Ravi A, Palamiuc L, Loughran RM, Triscott J, Arora GK, Kumar A, Tieu V, Pauli C, Reist M, Lew RJ, Houlihan SL, Fellmann C, Metallo C, Rubin MA, Emerling BM. PI5P4Ks drive metabolic homeostasis through peroxisome-mitochondria interplay. Developmental Cell. PMID 33984270 DOI: 10.1016/j.devcel.2021.04.019 |
0.316 |
|
| 2021 |
Cordes T, Metallo CM. Itaconate Alters Succinate and Coenzyme A Metabolism via Inhibition of Mitochondrial Complex II and Methylmalonyl-CoA Mutase. Metabolites. 11. PMID 33670656 DOI: 10.3390/metabo11020117 |
0.358 |
|
| 2020 |
Cordes T, Metallo CM. Exploring the evolutionary roots and physiological function of itaconate. Current Opinion in Biotechnology. 68: 144-150. PMID 33296743 DOI: 10.1016/j.copbio.2020.11.005 |
0.353 |
|
| 2020 |
Muthusamy T, Cordes T, Handzlik MK, You L, Lim EW, Gengatharan J, Pinto AFM, Badur MG, Kolar MJ, Wallace M, Saghatelian A, Metallo CM. Serine restriction alters sphingolipid diversity to constrain tumour growth. Nature. PMID 32788725 DOI: 10.1038/S41586-020-2609-X |
0.409 |
|
| 2020 |
Feyen DAM, McKeithan WL, Bruyneel AAN, Spiering S, Hörmann L, Ulmer B, Zhang H, Briganti F, Schweizer M, Hegyi B, Liao Z, Pölönen RP, Ginsburg KS, Lam CK, Serrano R, ... ... Metallo CM, et al. Metabolic Maturation Media Improve Physiological Function of Human iPSC-Derived Cardiomyocytes. Cell Reports. 32: 107925. PMID 32697997 DOI: 10.1016/J.Celrep.2020.107925 |
0.364 |
|
| 2020 |
Vaughan ME, Wallace M, Handzlik MK, Chan AB, Metallo CM, Lamia KA. Cryptochromes Suppress HIF1α in Muscles. Iscience. 23: 101338. PMID 32683313 DOI: 10.1016/J.Isci.2020.101338 |
0.347 |
|
| 2020 |
Kudo Y, Sugimoto M, Arias E, Kasashima H, Cordes T, Linares JF, Duran A, Nakanishi Y, Nakanishi N, L'Hermitte A, Campos A, Senni N, Rooslid T, Roberts LR, Cuervo AM, ... Metallo CM, et al. PKCλ/ι Loss Induces Autophagy, Oxidative Phosphorylation, and NRF2 to Promote Liver Cancer Progression. Cancer Cell. PMID 32589943 DOI: 10.1016/J.Ccell.2020.05.018 |
0.309 |
|
| 2020 |
Hong S, Dechaumphai E, Green CR, Lal R, Murphy AN, Metallo CM, Chen R. Sub-nanowatt microfluidic single-cell calorimetry. Nature Communications. 11: 2982. PMID 32532969 DOI: 10.1038/S41467-020-16697-5 |
0.405 |
|
| 2020 |
Liu X, Olszewski K, Zhang Y, Lim EW, Shi J, Zhang X, Zhang J, Lee H, Koppula P, Lei G, Zhuang L, You MJ, Fang B, Li W, Metallo CM, et al. Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer. Nature Cell Biology. PMID 32231310 DOI: 10.1038/S41556-020-0496-X |
0.451 |
|
| 2020 |
Wallace M, Metallo CM. Tracing insights into de novo lipogenesis in liver and adipose tissues. Seminars in Cell & Developmental Biology. PMID 32201132 DOI: 10.1016/J.Semcdb.2020.02.012 |
0.345 |
|
| 2020 |
Cordes T, Lucas A, Divakaruni AS, Murphy AN, Cabrales P, Metallo CM. Itaconate modulates tricarboxylic acid and redox metabolism to mitigate reperfusion injury. Molecular Metabolism. 32: 122-135. PMID 32029222 DOI: 10.1016/J.Molmet.2019.11.019 |
0.327 |
|
| 2020 |
Cordes T, Metallo CM. Statins Limit Coenzyme Q Synthesis and Metabolically Synergize with MEK Inhibition in Pancreatic Tumors. Cancer Research. 80: 151-152. PMID 31941676 DOI: 10.1158/0008-5472.Can-19-3415 |
0.369 |
|
| 2020 |
Lim EW, Parker SJ, Metallo CM. Deuterium Tracing to Interrogate Compartment-Specific NAD(P)H Metabolism in Cultured Mammalian Cells. Methods in Molecular Biology (Clifton, N.J.). 2088: 51-71. PMID 31893370 DOI: 10.1007/978-1-0716-0159-4_4 |
0.439 |
|
| 2019 |
Gao X, Zhao L, Liu S, Li Y, Xia S, Chen D, Wang M, Wu S, Dai Q, Vu H, Zacharias L, DeBerardinis R, Lim E, Metallo C, Boggon TJ, et al. γ-6-Phosphogluconolactone, a Byproduct of the Oxidative Pentose Phosphate Pathway, Contributes to AMPK Activation through Inhibition of PP2A. Molecular Cell. PMID 31586547 DOI: 10.1016/J.Molcel.2019.09.007 |
0.369 |
|
| 2019 |
Gantner ML, Eade K, Wallace M, Handzlik MK, Fallon R, Trombley J, Bonelli R, Giles S, Harkins-Perry S, Heeren TFC, Sauer L, Ideguchi Y, Baldini M, Scheppke L, Dorrell MI, ... ... Metallo CM, et al. Serine and Lipid Metabolism in Macular Disease and Peripheral Neuropathy. The New England Journal of Medicine. PMID 31509666 DOI: 10.1056/Nejmoa1815111 |
0.35 |
|
| 2019 |
Jung SM, Hung CM, Hildebrand SR, Sanchez-Gurmaches J, Martinez-Pastor B, Gengatharan JM, Wallace M, Mukhopadhyay D, Martinez Calejman C, Luciano AK, Hsiao WY, Tang Y, Li H, Daniels DL, Mostoslavsky R, ... Metallo CM, et al. Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1. Molecular Cell. 75: 807-822.e8. PMID 31442424 DOI: 10.1016/J.Molcel.2019.07.023 |
0.363 |
|
| 2019 |
Velez DO, Ranamukhaarachchi SK, Kumar A, Modi RN, Lim EW, Engler AJ, Metallo CM, Fraley SI. 3D collagen architecture regulates cell adhesion through degradability, thereby controlling metabolic and oxidative stress. Integrative Biology : Quantitative Biosciences From Nano to Macro. PMID 31251330 DOI: 10.1093/Intbio/Zyz019 |
0.372 |
|
| 2019 |
Fernandez S, Viola JM, Torres A, Wallace M, Trefely S, Zhao S, Affronti HC, Gengatharan JM, Guertin DA, Snyder NW, Metallo CM, Wellen KE. Adipocyte ACLY Facilitates Dietary Carbohydrate Handling to Maintain Metabolic Homeostasis in Females. Cell Reports. 27: 2772-2784.e6. PMID 31141698 DOI: 10.1016/J.Celrep.2019.04.112 |
0.386 |
|
| 2019 |
Cordes T, Metallo CM. Quantifying Intermediary Metabolism and Lipogenesis in Cultured Mammalian Cells Using Stable Isotope Tracing and Mass Spectrometry. Methods in Molecular Biology (Clifton, N.J.). 1978: 219-241. PMID 31119666 DOI: 10.1007/978-1-4939-9236-2_14 |
0.47 |
|
| 2019 |
Reina-Campos M, Linares JF, Duran A, Cordes T, L'Hermitte A, Badur MG, Bhangoo MS, Thorson PK, Richards A, Rooslid T, Garcia-Olmo DC, Nam-Cha SY, Salinas-Sanchez AS, Eng K, Beltran H, ... ... Metallo CM, et al. Increased Serine and One-Carbon Pathway Metabolism by PKCλ/ι Deficiency Promotes Neuroendocrine Prostate Cancer. Cancer Cell. PMID 30827887 DOI: 10.1016/J.Ccell.2019.01.018 |
0.347 |
|
| 2019 |
Garcia D, Hellberg K, Chaix A, Wallace M, Herzig S, Badur MG, Lin T, Shokhirev MN, Pinto AFM, Ross DS, Saghatelian A, Panda S, Dow LE, Metallo CM, Shaw RJ. Genetic Liver-Specific AMPK Activation Protects against Diet-Induced Obesity and NAFLD. Cell Reports. 26: 192-208.e6. PMID 30605676 DOI: 10.1016/J.Celrep.2018.12.036 |
0.336 |
|
| 2019 |
WORTHAM M, LIU F, FLEISCHMAN J, WALLACE M, HARRINGTON AR, CHIOU J, GAULTON K, METALLO C, SANDER M. 4-LB: Feeding-Stimulated Regulation of the Epigenome Controls Adaptive Insulin Secretion Diabetes. 68: 4-LB. DOI: 10.2337/Db19-4-Lb |
0.334 |
|
| 2019 |
Weeks JL, Wells G, Alexander S, Metallo C, Sohl CD. Abstract 4381: Investigating the reversible MDH1 catalytic reaction in squamous non-small cell lung cancer Cancer Research. 79: 4381-4381. DOI: 10.1158/1538-7445.Am2019-4381 |
0.393 |
|
| 2018 |
Wortham M, Benthuysen JR, Wallace M, Savas JN, Mulas F, Divakaruni AS, Liu F, Albert V, Taylor BL, Sui Y, Saez E, Murphy AN, Yates JR, Metallo CM, Sander M. Integrated In Vivo Quantitative Proteomics and Nutrient Tracing Reveals Age-Related Metabolic Rewiring of Pancreatic β Cell Function. Cell Reports. 25: 2904-2918.e8. PMID 30517875 DOI: 10.1016/J.Celrep.2018.11.031 |
0.378 |
|
| 2018 |
Badur MG, Muthusamy T, Parker SJ, Ma S, McBrayer SK, Cordes T, Magana JH, Guan KL, Metallo CM. Oncogenic R132 IDH1 Mutations Limit NADPH for De Novo Lipogenesis through (D)2-Hydroxyglutarate Production in Fibrosarcoma Sells. Cell Reports. 25: 1018-1026.e4. PMID 30355481 DOI: 10.1016/J.Celrep.2018.09.074 |
0.414 |
|
| 2018 |
Wallace M, Green CR, Roberts LS, Lee YM, McCarville JL, Sanchez-Gurmaches J, Meurs N, Gengatharan JM, Hover JD, Phillips SA, Ciaraldi TP, Guertin DA, Cabrales P, Ayres JS, Nomura DK, ... ... Metallo CM, et al. Enzyme promiscuity drives branched-chain fatty acid synthesis in adipose tissues. Nature Chemical Biology. 14: 1021-1031. PMID 30327559 DOI: 10.1038/S41589-018-0132-2 |
0.33 |
|
| 2018 |
Skorobogatko Y, Dragan M, Cordon C, Reilly SM, Hung CW, Xia W, Zhao P, Wallace M, Lackey DE, Chen XW, Osborn O, Bogner-Strauss JG, Theodorescu D, Metallo CM, Olefsky JM, et al. RalA controls glucose homeostasis by regulating glucose uptake in brown fat. Proceedings of the National Academy of Sciences of the United States of America. PMID 29915037 DOI: 10.1073/Pnas.1801050115 |
0.311 |
|
| 2018 |
Zhao D, Badur MG, Luebeck J, Magaña JH, Birmingham A, Sasik R, Ahn CS, Ideker T, Metallo CM, Mali P. Combinatorial CRISPR-Cas9 Metabolic Screens Reveal Critical Redox Control Points Dependent on the KEAP1-NRF2 Regulatory Axis. Molecular Cell. 69: 699-708.e7. PMID 29452643 DOI: 10.1016/J.Molcel.2018.01.017 |
0.428 |
|
| 2017 |
Badur MG, Metallo CM. Reverse engineering the cancer metabolic network using flux analysis to understand drivers of human disease. Metabolic Engineering. 45: 95-108. PMID 29199104 DOI: 10.1016/J.Ymben.2017.11.013 |
0.426 |
|
| 2017 |
Sanchez-Gurmaches J, Tang Y, Jespersen NZ, Wallace M, Martinez Calejman C, Gujja S, Li H, Edwards YJK, Wolfrum C, Metallo CM, Nielsen S, Scheele C, Guertin DA. Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis. Cell Metabolism. PMID 29153407 DOI: 10.1016/J.Cmet.2017.10.008 |
0.406 |
|
| 2017 |
Linares JF, Cordes T, Duran A, Reina-Campos M, Valencia T, Ahn CS, Castilla EA, Moscat J, Metallo CM, Diaz-Meco MT. ATF4-Induced Metabolic Reprograming Is a Synthetic Vulnerability of the p62-Deficient Tumor Stroma. Cell Metabolism. PMID 28988820 DOI: 10.1016/J.Cmet.2017.09.001 |
0.359 |
|
| 2017 |
Metallo CM, Deberardinis RJ. Engineering approaches to study cancer metabolism. Metabolic Engineering. 43: 93. PMID 28918847 DOI: 10.1016/J.Ymben.2017.09.002 |
0.372 |
|
| 2017 |
Zarei M, Lal S, Parker SJ, Nevler A, Vaziri-Gohar A, Dukleska K, Mambelli-Lisboa NC, Moffat C, Blanco FF, Chand SN, Jimbo M, Cozzitorto JA, Jiang W, Yeo CJ, Londin E, ... ... Metallo CM, et al. Posttranscriptional upregulation of IDH1 by HuR establishes a powerful survival phenotype in pancreatic cancer cells. Cancer Research. PMID 28652247 DOI: 10.1158/0008-5472.Can-17-0015 |
0.357 |
|
| 2017 |
Divakaruni AS, Wallace M, Buren C, Martyniuk K, Andreyev AY, Li E, Fields JA, Cordes T, Reynolds IJ, Bloodgood BL, Raymond LA, Metallo CM, Murphy AN. Inhibition of the mitochondrial pyruvate carrier protects from excitotoxic neuronal death. The Journal of Cell Biology. PMID 28254829 DOI: 10.1083/Jcb.201612067 |
0.332 |
|
| 2016 |
Cordes T, Metallo CM. Tracing insights into human metabolism using chemical engineering approaches. Current Opinion in Chemical Engineering. 14: 72-81. PMID 28480159 DOI: 10.1016/J.Coche.2016.08.019 |
0.445 |
|
| 2016 |
Parker SJ, Svensson RU, Divakaruni AS, Lefebvre AE, Murphy AN, Shaw RJ, Metallo CM. LKB1 promotes metabolic flexibility in response to energy stress. Metabolic Engineering. PMID 28034771 DOI: 10.1016/J.Ymben.2016.12.010 |
0.464 |
|
| 2016 |
Huber AL, Papp SJ, Chan AB, Henriksson E, Jordan SD, Kriebs A, Nguyen M, Wallace M, Li Z, Metallo CM, Lamia KA. CRY2 and FBXL3 Cooperatively Degrade c-MYC. Molecular Cell. PMID 27840026 DOI: 10.1016/J.Molcel.2016.10.012 |
0.322 |
|
| 2016 |
Zhao S, Torres A, Henry RA, Trefely S, Wallace M, Lee JV, Carrer A, Sengupta A, Campbell SL, Kuo YM, Frey AJ, Meurs N, Viola JM, Blair IA, Weljie AM, ... Metallo CM, et al. ATP-Citrate Lyase Controls a Glucose-to-Acetate Metabolic Switch. Cell Reports. 17: 1037-1052. PMID 27760311 DOI: 10.1016/J.Celrep.2016.09.069 |
0.453 |
|
| 2016 |
Svensson RU, Parker SJ, Eichner LJ, Kolar MJ, Wallace M, Brun SN, Lombardo PS, Van Nostrand JL, Hutchins A, Vera L, Gerken L, Greenwood J, Bhat S, Harriman G, Westlin WF, ... ... Metallo CM, et al. Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models. Nature Medicine. PMID 27643638 DOI: 10.1038/Nm.4181 |
0.341 |
|
| 2016 |
Zhang H, Badur MG, Divakaruni AS, Parker SJ, Jäger C, Hiller K, Murphy AN, Metallo CM. Distinct Metabolic States Can Support Self-Renewal and Lipogenesis in Human Pluripotent Stem Cells under Different Culture Conditions. Cell Reports. PMID 27477285 DOI: 10.1016/J.Celrep.2016.06.102 |
0.481 |
|
| 2016 |
Wallace M, Metallo CM. PGC1α drives a metabolic block on prostate cancer progression. Nature Cell Biology. 18: 589-90. PMID 27230528 DOI: 10.1038/Ncb3365 |
0.357 |
|
| 2016 |
Cordes T, Wallace M, Michelucci A, Divakaruni AS, Sapcariu SC, Sousa C, Koseki H, Cabrales P, Murphy AN, Hiller K, Metallo CM. Immunoresponsive gene 1 and itaconate inhibit succinate dehydrogenase to modulate intracellular succinate levels. The Journal of Biological Chemistry. PMID 27189937 DOI: 10.1074/Jbc.M115.685792 |
0.332 |
|
| 2016 |
Tang Y, Wallace M, Sanchez-Gurmaches J, Hsiao WY, Li H, Lee PL, Vernia S, Metallo CM, Guertin DA. Adipose tissue mTORC2 regulates ChREBP-driven de novo lipogenesis and hepatic glucose metabolism. Nature Communications. 7: 11365. PMID 27098609 DOI: 10.1038/Ncomms11365 |
0.303 |
|
| 2016 |
Jiang L, Shestov AA, Swain P, Yang C, Parker SJ, Wang QA, Terada LS, Adams ND, McCabe MT, Pietrak B, Schmidt S, Metallo CM, Dranka BP, Schwartz B, DeBerardinis RJ. Reductive carboxylation supports redox homeostasis during anchorage-independent growth. Nature. PMID 27049945 DOI: 10.1038/Nature17393 |
0.412 |
|
| 2016 |
Parker SJ, Metallo CM. Chasing One-Carbon Units to Understand the Role of Serine in Epigenetics. Molecular Cell. 61: 185-6. PMID 26799763 DOI: 10.1016/J.Molcel.2016.01.006 |
0.314 |
|
| 2016 |
Metallo C. Abstract PR07: Functional identification of a mitochondrial glutamine carrier using isotope tracers Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Metca15-Pr07 |
0.472 |
|
| 2015 |
Green CR, Wallace M, Divakaruni AS, Phillips SA, Murphy AN, Ciaraldi TP, Metallo CM. Branched-chain amino acid catabolism fuels adipocyte differentiation and lipogenesis. Nature Chemical Biology. PMID 26571352 DOI: 10.1038/Nchembio.1961 |
0.424 |
|
| 2015 |
Lussey-Lepoutre C, Hollinshead KE, Ludwig C, Menara M, Morin A, Castro-Vega LJ, Parker SJ, Janin M, Martinelli C, Ottolenghi C, Metallo C, Gimenez-Roqueplo AP, Favier J, Tennant DA. Loss of succinate dehydrogenase activity results in dependency on pyruvate carboxylation for cellular anabolism. Nature Communications. 6: 8784. PMID 26522426 DOI: 10.1038/Ncomms9784 |
0.49 |
|
| 2015 |
Metallo CM. Metabolic Analysis Using Stable Isotopes. Preface. Methods in Enzymology. 561: xv-xvi. PMID 26358911 DOI: 10.1016/S0076-6879(15)00482-6 |
0.381 |
|
| 2015 |
Badur MG, Zhang H, Metallo CM. Enzymatic passaging of human embryonic stem cells alters central carbon metabolism and glycan abundance. Biotechnology Journal. 10: 1600-11. PMID 26289220 DOI: 10.1002/Biot.201400749 |
0.501 |
|
| 2015 |
Parker SJ, Metallo CM. Metabolic consequences of oncogenic IDH mutations. Pharmacology & Therapeutics. PMID 25956465 DOI: 10.1016/J.Pharmthera.2015.05.003 |
0.348 |
|
| 2015 |
Buescher JM, Antoniewicz MR, Boros LG, Burgess SC, Brunengraber H, Clish CB, DeBerardinis RJ, Feron O, Frezza C, Ghesquiere B, Gottlieb E, Hiller K, Jones RG, Kamphorst JJ, Kibbey RG, ... ... Metallo CM, et al. A roadmap for interpreting (13)C metabolite labeling patterns from cells. Current Opinion in Biotechnology. 34: 189-201. PMID 25731751 DOI: 10.1016/J.Copbio.2015.02.003 |
0.349 |
|
| 2015 |
Ahn CS, Metallo CM. Mitochondria as biosynthetic factories for cancer proliferation. Cancer & Metabolism. 3: 1. PMID 25621173 DOI: 10.1186/S40170-015-0128-2 |
0.435 |
|
| 2015 |
Moscat J, Linares JF, Duran A, Valencia T, Ahn CS, Metallo C, Diaz-Meco MT. Abstract SY01-02: Autophagy and metabolic reprogramming in the tumor stroma Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Sy01-02 |
0.415 |
|
| 2014 |
Vacanti NM, Divakaruni AS, Green CR, Parker SJ, Henry RR, Ciaraldi TP, Murphy AN, Metallo CM. Regulation of substrate utilization by the mitochondrial pyruvate carrier. Molecular Cell. 56: 425-35. PMID 25458843 DOI: 10.1016/J.Molcel.2014.09.024 |
0.406 |
|
| 2014 |
Valencia T, Kim JY, Abu-Baker S, Moscat-Pardos J, Ahn CS, Reina-Campos M, Duran A, Castilla EA, Metallo CM, Diaz-Meco MT, Moscat J. Metabolic reprogramming of stromal fibroblasts through p62-mTORC1 signaling promotes inflammation and tumorigenesis. Cancer Cell. 26: 121-35. PMID 25002027 DOI: 10.1016/J.Ccr.2014.05.004 |
0.392 |
|
| 2014 |
Lewis CA, Parker SJ, Fiske BP, McCloskey D, Gui DY, Green CR, Vokes NI, Feist AM, Vander Heiden MG, Metallo CM. Tracing compartmentalized NADPH metabolism in the cytosol and mitochondria of mammalian cells. Molecular Cell. 55: 253-63. PMID 24882210 DOI: 10.1016/J.Molcel.2014.05.008 |
0.444 |
|
| 2014 |
Grassian AR, Parker SJ, Davidson SM, Divakaruni AS, Green CR, Zhang X, Slocum KL, Pu M, Lin F, Vickers C, Joud-Caldwell C, Chung F, Yin H, Handly ED, Straub C, ... ... Metallo CM, et al. IDH1 mutations alter citric acid cycle metabolism and increase dependence on oxidative mitochondrial metabolism. Cancer Research. 74: 3317-31. PMID 24755473 DOI: 10.1158/0008-5472.Can-14-0772-T |
0.452 |
|
| 2014 |
Heinrichsen ET, Zhang H, Robinson JE, Ngo J, Diop S, Bodmer R, Joiner WJ, Metallo CM, Haddad GG. Metabolic and transcriptional response to a high-fat diet in Drosophila melanogaster. Molecular Metabolism. 3: 42-54. PMID 24567903 DOI: 10.1016/J.Molmet.2013.10.003 |
0.39 |
|
| 2014 |
Grassian AR, Parker S, Davidson S, Divakaruni A, Green C, Zhang X, Slocum K, Pu M, Lin F, Vickers C, Joud-Caldwell C, Chung F, Yin H, Handly E, Straub C, ... ... Metallo C, et al. Abstract LB-139: IDH1 mutations alter citric acid cycle metabolism and increase dependence on oxidative mitochondrial metabolism Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-139 |
0.464 |
|
| 2014 |
Metallo CM, Zhang H. Metabolic impact of culture media on pluripotent stem cell growth and differentiation 4th International Conference On Stem Cell Engineering 2014. 297-298. |
0.345 |
|
| 2013 |
Commisso C, Davidson SM, Soydaner-Azeloglu RG, Parker SJ, Kamphorst JJ, Hackett S, Grabocka E, Nofal M, Drebin JA, Thompson CB, Rabinowitz JD, Metallo CM, Vander Heiden MG, Bar-Sagi D. Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells. Nature. 497: 633-7. PMID 23665962 DOI: 10.1038/Nature12138 |
0.37 |
|
| 2013 |
Hiller K, Wegner A, Weindl D, Cordes T, Metallo CM, Kelleher JK, Stephanopoulos G. NTFD--a stand-alone application for the non-targeted detection of stable isotope-labeled compounds in GC/MS data. Bioinformatics (Oxford, England). 29: 1226-8. PMID 23479350 DOI: 10.1093/Bioinformatics/Btt119 |
0.318 |
|
| 2013 |
Metallo CM, Vander Heiden MG. Understanding Metabolic Regulation and Its Influence on Cell Physiology Molecular Cell. 49: 388-398. PMID 23395269 DOI: 10.1016/J.Molcel.2013.01.018 |
0.46 |
|
| 2013 |
Hiller K, Metallo CM. Profiling metabolic networks to study cancer metabolism. Current Opinion in Biotechnology. 24: 60-8. PMID 23206561 DOI: 10.1016/J.Copbio.2012.11.001 |
0.449 |
|
| 2013 |
Vacanti NM, Metallo CM. Exploring metabolic pathways that contribute to the stem cell phenotype. Biochimica Et Biophysica Acta. 1830: 2361-9. PMID 22917650 DOI: 10.1016/J.Bbagen.2012.08.007 |
0.506 |
|
| 2013 |
Grassian AR, Parker S, Davidson S, Green C, Lin F, Joud-Caldwell C, Yin H, Chung F, Straub C, Heiden MV, Pagliarini R, Metallo C. Abstract B159: Heterozygous IDH1 mutations modify the citric acid (TCA) cycle metabolism and sensitize cells to inhibition of mitochondrial respiration/oxidative phosphorylation. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-B159 |
0.43 |
|
| 2012 |
Metallo CM. Expanding the reach of cancer metabolomics. Cancer Prevention Research (Philadelphia, Pa.). 5: 1337-40. PMID 23151806 DOI: 10.1158/1940-6207.Capr-12-0433 |
0.383 |
|
| 2012 |
Anastasiou D, Yu Y, Israelsen WJ, Jiang JK, Boxer MB, Hong BS, Tempel W, Dimov S, Shen M, Jha A, Yang H, Mattaini KR, Metallo CM, Fiske BP, Courtney KD, et al. Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis. Nature Chemical Biology. 8: 839-47. PMID 22922757 DOI: 10.1038/Nchembio.1060 |
0.382 |
|
| 2012 |
Walther JL, Metallo CM, Zhang J, Stephanopoulos G. Optimization of 13C isotopic tracers for metabolic flux analysis in mammalian cells. Metabolic Engineering. 14: 162-71. PMID 22198197 DOI: 10.1016/J.Ymben.2011.12.004 |
0.43 |
|
| 2012 |
Metallo CM, Gameiro PA, Bell EL, Mattaini KR, Yang J, Hiller K, Jewell CM, Johnson ZR, Irvine DJ, Guarente L, Kelleher JK, Vander Heiden MG, Iliopoulos O, Stephanopoulos G. Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia Nature. 481: 380-384. PMID 22101433 DOI: 10.1038/Nature10602 |
0.478 |
|
| 2012 |
Commisso C, Davidson SM, Soydaner-Azeloglu RG, Parker SJ, Metallo CM, Heiden MGV, Bar-Sagi D. Abstract PR5: Macropinocytosis as a mechanism of amino acid supply. Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-Pr5 |
0.385 |
|
| 2012 |
Metallo C, Gameiro P, Heiden MV, Ilioupoulos O, Stephanopoulos G. Abstract 1001: Reductive tricarboxylic acid metabolism of glutamine mediates lipogenesis under hypoxia Cancer Research. 72: 1001-1001. DOI: 10.1158/1538-7445.Am2012-1001 |
0.474 |
|
| 2012 |
Gameiro PA, Metallo CM, Stephanopoulos G. Systems-level analysis of cancer metabolism Systems Metabolic Engineering. 2147483647: 349-381. DOI: 10.1007/978-94-007-4534-6_11 |
0.304 |
|
| 2011 |
Vander Heiden MG, Lunt SY, Dayton TL, Fiske BP, Israelsen WJ, Mattaini KR, Vokes NI, Stephanopoulos G, Cantley LC, Metallo CM, Locasale JW. Metabolic pathway alterations that support cell proliferation. Cold Spring Harbor Symposia On Quantitative Biology. 76: 325-34. PMID 22262476 DOI: 10.1101/Sqb.2012.76.010900 |
0.513 |
|
| 2011 |
Grassian AR, Metallo CM, Coloff JL, Stephanopoulos G, Brugge JS. Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation. Genes & Development. 25: 1716-33. PMID 21852536 DOI: 10.1101/Gad.16771811 |
0.465 |
|
| 2011 |
Gaglio D, Metallo CM, Gameiro PA, Hiller K, Danna LS, Balestrieri C, Alberghina L, Stephanopoulos G, Chiaradonna F. Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth. Molecular Systems Biology. 7: 523. PMID 21847114 DOI: 10.1038/Msb.2011.56 |
0.429 |
|
| 2011 |
Locasale JW, Grassian AR, Melman T, Lyssiotis CA, Mattaini KR, Bass AJ, Heffron G, Metallo CM, Muranen T, Sharfi H, Sasaki AT, Anastasiou D, Mullarky E, Vokes NI, Sasaki M, et al. Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis. Nature Genetics. 43: 869-74. PMID 21804546 DOI: 10.1038/Ng.890 |
0.458 |
|
| 2011 |
Hiller K, Metallo C, Stephanopoulos G. Elucidation of cellular metabolism via metabolomics and stable-isotope assisted metabolomics Current Pharmaceutical Biotechnology. 12: 1075-1086. PMID 21466455 DOI: 10.2174/138920111795909096 |
0.371 |
|
| 2011 |
Grassian AR, Metallo CM, Stephanopoulos G, Brugge JS. Abstract 2802: Evaluation of metabolic changes induced by loss of extracellular matrix attachment using 13C Flux analysis Cancer Research. 71: 2802-2802. DOI: 10.1158/1538-7445.Am2011-2802 |
0.456 |
|
| 2010 |
Metallo CM, Vander Heiden MG. Metabolism strikes back: Metabolic flux regulates cell signaling Genes and Development. 24: 2717-2722. PMID 21159812 DOI: 10.1101/Gad.2010510 |
0.459 |
|
| 2010 |
Hiller K, Metallo CM, Kelleher JK, Stephanopoulos G. Nontargeted elucidation of metabolic pathways using stable-isotope tracers and mass spectrometry. Analytical Chemistry. 82: 6621-8. PMID 20608743 DOI: 10.1021/Ac1011574 |
0.375 |
|
| 2010 |
Metallo CM, Ji L, de Pablo JJ, Palecek SP. Directed differentiation of human embryonic stem cells to epidermal progenitors. Methods in Molecular Biology (Clifton, N.J.). 585: 83-92. PMID 19907998 DOI: 10.1007/978-1-60761-380-0_7 |
0.559 |
|
| 2010 |
Metallo CM, Azarin SM, Moses LE, Ji L, de Pablo JJ, Palecek SP. Human embryonic stem cell-derived keratinocytes exhibit an epidermal transcription program and undergo epithelial morphogenesis in engineered tissue constructs. Tissue Engineering. Part A. 16: 213-23. PMID 19686061 DOI: 10.1089/Ten.Tea.2009.0325 |
0.71 |
|
| 2010 |
Stephanopoulos G, Metallo C. Developing an integrated picture of tumor cell physiology using isotope tracer data and metabolic flux analysis Journal of Biotechnology. 150: 91-92. DOI: 10.1016/J.Jbiotec.2010.08.236 |
0.403 |
|
| 2009 |
Metallo CM, Walther JL, Stephanopoulos G. Evaluation of 13C isotopic tracers for metabolic flux analysis in mammalian cells. Journal of Biotechnology. 144: 167-74. PMID 19622376 DOI: 10.1016/J.Jbiotec.2009.07.010 |
0.419 |
|
| 2008 |
Metallo CM, Vodyanik MA, de Pablo JJ, Slukvin II, Palecek SP. The response of human embryonic stem cell-derived endothelial cells to shear stress. Biotechnology and Bioengineering. 100: 830-7. PMID 18306423 DOI: 10.1002/Bit.21809 |
0.523 |
|
| 2008 |
Metallo CM, Azarin SM, Ji L, de Pablo JJ, Palecek SP. Engineering tissue from human embryonic stem cells. Journal of Cellular and Molecular Medicine. 12: 709-29. PMID 18194458 DOI: 10.1111/J.1582-4934.2008.00228.X |
0.709 |
|
| 2008 |
Metallo CM, Ji L, de Pablo JJ, Palecek SP. Retinoic acid and bone morphogenetic protein signaling synergize to efficiently direct epithelial differentiation of human embryonic stem cells. Stem Cells (Dayton, Ohio). 26: 372-80. PMID 17962700 DOI: 10.1634/Stemcells.2007-0501 |
0.534 |
|
| 2007 |
Metallo CM, Mohr JC, Detzel CJ, de Pablo JJ, Van Wie BJ, Palecek SP. Engineering the stem cell microenvironment. Biotechnology Progress. 23: 18-23. PMID 17269664 DOI: 10.1021/Bp060350A |
0.725 |
|
| 2002 |
Xie L, Pilbrough W, Metallo C, Zhong T, Pikus L, Leung J, Auniņš JG, Zhou W. Serum-free suspension cultivation of PER.C6® cells and recombinant adenovirus production under different pH conditions Biotechnology and Bioengineering. 80: 569-579. PMID 12355468 DOI: 10.1002/Bit.10443 |
0.326 |
|
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