Patrick Aebischer - Publications

Affiliations: 
1984-1992 Medical Sciences Brown University, Providence, RI 
 1999- École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland 

65 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Lathuilière A, Cosson S, Lutolf MP, Schneider BL, Aebischer P. A high-capacity cell macroencapsulation system supporting the long-term survival of genetically engineered allogeneic cells. Biomaterials. 35: 779-91. PMID 24103654 DOI: 10.1016/j.biomaterials.2013.09.071  0.318
2013 Kunze A, Lengacher S, Dirren E, Aebischer P, Magistretti PJ, Renaud P. Astrocyte-neuron co-culture on microchips based on the model of SOD mutation to mimic ALS. Integrative Biology : Quantitative Biosciences From Nano to Macro. 5: 964-75. PMID 23695230 DOI: 10.1039/C3Ib40022K  0.672
2007 Consiglio A, Martino S, Dolcetta D, Cusella G, Conese M, Marchesini S, Benaglia G, Wrabetz L, Orlacchio A, Déglon N, Aebischer P, Severini GM, Bordignon C. Metabolic correction in oligodendrocytes derived from metachromatic leukodystrophy mouse model by using encapsulated recombinant myoblasts. Journal of the Neurological Sciences. 255: 7-16. PMID 17341424 DOI: 10.1016/J.Jns.2007.01.010  0.388
2006 Behrstock S, Ebert A, McHugh J, Vosberg S, Moore J, Schneider B, Capowski E, Hei D, Kordower J, Aebischer P, Svendsen CN. Human neural progenitors deliver glial cell line-derived neurotrophic factor to parkinsonian rodents and aged primates. Gene Therapy. 13: 379-88. PMID 16355116 DOI: 10.1038/Sj.Gt.3302679  0.393
2006 Aebischer P, Wahlberg L, Tresco PA, Winn SR. Macroencapsulation of dopamine-secreting cells by coextrusion with an organic polymer solution1 The Biomaterials: Silver Jubilee Compendium. 61-67. DOI: 10.1016/B978-008045154-1.50009-5  0.639
2005 Ahn YH, Bensadoun JC, Aebischer P, Zurn AD, Seiger A, Björklund A, Lindvall O, Wahlberg L, Brundin P, Kaminski Schierle GS. Increased fiber outgrowth from xeno-transplanted human embryonic dopaminergic neurons with co-implants of polymer-encapsulated genetically modified cells releasing glial cell line-derived neurotrophic factor. Brain Research Bulletin. 66: 135-42. PMID 15982530 DOI: 10.1016/J.Brainresbull.2005.04.009  0.36
2005 Sajadi A, Bauer M, Thöny B, Aebischer P. Long-term glial cell line-derived neurotrophic factor overexpression in the intact nigrostriatal system in rats leads to a decrease of dopamine and increase of tetrahydrobiopterin production. Journal of Neurochemistry. 93: 1482-6. PMID 15935064 DOI: 10.1111/j.1471-4159.2005.03139.x  0.309
2004 Bloch J, Bachoud-Lévi AC, Déglon N, Lefaucheur JP, Winkel L, Palfi S, Nguyen JP, Bourdet C, Gaura V, Remy P, Brugières P, Boisse MF, Baudic S, Cesaro P, Hantraye P, ... Aebischer P, et al. Neuroprotective gene therapy for Huntington's disease, using polymer-encapsulated cells engineered to secrete human ciliary neurotrophic factor: results of a phase I study. Human Gene Therapy. 15: 968-75. PMID 15585112 DOI: 10.1089/Hum.2004.15.968  0.309
2004 Schwenter F, Schneider BL, Pralong WF, Déglon N, Aebischer P. Survival of encapsulated human primary fibroblasts and erythropoietin expression under xenogeneic conditions. Human Gene Therapy. 15: 669-80. PMID 15242527 DOI: 10.1089/1043034041361172  0.324
2003 Bjerkvig R, Read TA, Vajkoczy P, Aebischer P, Pralong W, Platt S, Melvik JE, Hagen A, Dornish M. Cell therapy using encapsulated cells producing endostatin. Acta Neurochirurgica. Supplement. 88: 137-41. PMID 14531571 DOI: 10.1007/978-3-7091-6090-9_19  0.333
2003 Schneider BL, Schwenter F, Pralong WF, Aebischer P. Prevention of the initial host immuno-inflammatory response determines the long-term survival of encapsulated myoblasts genetically engineered for erythropoietin delivery. Molecular Therapy : the Journal of the American Society of Gene Therapy. 7: 506-14. PMID 12727114 DOI: 10.1016/S1525-0016(03)00055-8  0.316
2003 Bensadoun JC, Pereira de Almeida L, Fine EG, Tseng JL, Déglon N, Aebischer P. Comparative study of GDNF delivery systems for the CNS: polymer rods, encapsulated cells, and lentiviral vectors. Journal of Controlled Release : Official Journal of the Controlled Release Society. 87: 107-15. PMID 12618027 DOI: 10.1016/S0168-3659(02)00353-X  0.404
2002 Ostenfeld T, Tai YT, Martin P, Déglon N, Aebischer P, Svendsen CN. Neurospheres modified to produce glial cell line-derived neurotrophic factor increase the survival of transplanted dopamine neurons. Journal of Neuroscience Research. 69: 955-65. PMID 12205689 DOI: 10.1002/jnr.10396  0.352
2000 Peduto G, Rinsch C, Schneider BL, Rolland E, Aebischer P. Long-term host unresponsiveness to encapsulated xenogeneic myoblasts after transient immunosuppression. Transplantation. 70: 78-85. PMID 10919579  0.336
1999 Boison D, Scheurer L, Tseng JL, Aebischer P, Mohler H. Seizure suppression in kindled rats by intraventricular grafting of an adenosine releasing synthetic polymer Experimental Neurology. 160: 164-174. PMID 10630201 DOI: 10.1006/Exnr.1999.7209  0.308
1999 Lysaght MJ, Aebischer P. Encapsulated cells as therapy. Scientific American. 280: 76-82. PMID 10201119 DOI: 10.1038/Scientificamerican0499-76  0.305
1998 Décosterd I, Buchser E, Gilliard N, Saydoff J, Zurn AD, Aebischer P. Intrathecal implants of bovine chromaffin cells alleviate mechanical allodynia in a rat model of neuropathic pain Pain. 76: 159-166. PMID 9696469 DOI: 10.1016/S0304-3959(98)00044-X  0.303
1998 Tseng JL, Bruhn SL, Zurn AD, Aebischer P. Neurturin protects dopaminergic neurons following medial forebrain bundle axotomy. Neuroreport. 9: 1817-22. PMID 9665607  0.385
1998 Sautter J, Tseng JL, Braguglia D, Aebischer P, Spenger C, Seiler RW, Widmer HR, Zurn AD. Implants of polymer-encapsulated genetically modified cells releasing glial cell line-derived neurotrophic factor improve survival, growth, and function of fetal dopaminergic grafts Experimental Neurology. 149: 230-236. PMID 9454632 DOI: 10.1006/exnr.1997.6718  0.395
1997 Tseng JL, Baetge EE, Zurn AD, Aebischer P. GDNF reduces drug-induced rotational behavior after medial forebrain bundle transection by a mechanism not involving striatal dopamine Journal of Neuroscience. 17: 325-333. PMID 8987758  0.354
1997 Déglon N, Heyd B, Tan SA, Joseph JM, Zurn AD, Aebischer P. Central nervous system delivery of recombinant ciliary neurotrophic factor by polymer encapsulated differentiated C2C12 myoblasts. Human Gene Therapy. 7: 2135-46. PMID 8934227 DOI: 10.1089/hum.1996.7.17-2135  0.391
1997 Aebischer P, Pochon NA, Heyd B, Deglon N, Joseph JM, Zurn AD, Baetge EE, Hammang JP, Goddard M, Lysaght M, Kaplan F, Kato AC, Schluep M, Hirt L, Regli F, et al. Gene therapy for amyotrophic lateral sclerosis (ALS) using a polymer encapsulated xenogenic cell line engineered to secrete hCNTF. Human Gene Therapy. 7: 851-60. PMID 8860837 DOI: 10.1089/hum.1996.7.7-851  0.354
1996 Aebischer P, Schluep M, Déglon N, Joseph JM, Hirt L, Heyd B, Goddard M, Hammang JP, Zurn AD, Kato AC, Regli F, Baetge EE. Intrathecal delivery of CNTF using encapsulated genetically modified xenogeneic cells in amyotrophic lateral sclerosis patients. Nature Medicine. 2: 696-9. PMID 8640564 DOI: 10.1038/nm0696-696  0.313
1996 Tan S, Déglon N, Zurn A, Baetge E, Bamber B, Kato A, Aebischer P. Rescue of Motoneurons from Axotomy-Induced Cell Death by Polymer Encapsulated Cells Genetically Engineered to Release CNTF Cell Transplantation. 5: 577-587. DOI: 10.1177/096368979600500507  0.34
1996 Joseph JM, Degion N, Schluep M, Hirt L, Martinet O, Baetge E, Goddard M, Zurn A, Regli F, Aebischer P. Transplantation of an encapsulated genetically engineered cell line releasing ciliary neurotrophic factor in LOU gehrig disease Cell Transplantation. 5: 80. DOI: 10.1016/0963-6897(96)82323-2  0.376
1995 Aebischer P, Kato AC. Treatment of amyotrophic lateral sclerosis using a gene therapy approach. European Neurology. 35: 65-8. PMID 7796839 DOI: 10.1159/000117095  0.337
1995 Zurn AD, Baetge EE, Hammang JP, Tan SA, Aebischer P. Glial cell line-derived neurotrophic factor (GDNF), a new neurotrophic factor for motoneurones. Neuroreport. 6: 113-8. PMID 7703397 DOI: 10.1097/00001756-199412300-00030  0.353
1995 Vargo TG, Bekos EJ, Kim YS, Ranieri JP, Bellamkonda R, Aebischer P, Margevich DE, Thompson PM, Bright FV, Gardella JA. Synthesis and characterization of fluoropolymeric substrata with immobilized minimal peptide sequences for cell adhesion studies. I. Journal of Biomedical Materials Research. 29: 767-78. PMID 7593014 DOI: 10.1002/Jbm.820290613  0.556
1995 Sagot Y, Tan SA, Baetge E, Schmalbruch H, Kato AC, Aebischer P. Polymer encapsulated cell lines genetically engineered to release ciliary neurotrophic factor can slow down progressive motor neuronopathy in the mouse. The European Journal of Neuroscience. 7: 1313-22. PMID 7582105 DOI: 10.1111/j.1460-9568.1995.tb01122.x  0.395
1994 Guénard V, Aebischer P, Bunge RP. The astrocyte inhibition of peripheral nerve regeneration is reversed by Schwann cells. Experimental Neurology. 126: 44-60. PMID 8157126 DOI: 10.1006/exnr.1994.1041  0.323
1994 Aebischer P, Goddard M, Signore AP, Timpson RL. Functional Recovery in Hemiparkinsonian Primates Transplanted with Polymer-Encapsulated PC12 Cells Experimental Neurology. 126: 151-158. PMID 7925816 DOI: 10.1006/Exnr.1994.1053  0.543
1994 Zielinski BA, Aebischer P. Chitosan as a matrix for mammalian cell encapsulation. Biomaterials. 15: 1049-56. PMID 7888575 DOI: 10.1016/0142-9612(94)90090-6  0.499
1993 Hoffman D, Breakefield XO, Short MP, Aebischer P. Transplantation of a polymer-encapsulated cell line genetically engineered to release NGF. Experimental Neurology. 122: 100-6. PMID 8339781 DOI: 10.1006/exnr.1993.1111  0.427
1993 Sagen J, Wang H, Tresco PA, Aebischer P. Transplants of immunologically isolated xenogeneic chromaffin cells provide a long-term source of pain-reducing neuroactive substances. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 2415-23. PMID 7684773 DOI: 10.1523/Jneurosci.13-06-02415.1993  0.651
1993 Sanberg PR, Emerich DF, Aebischer P, Amisetti SM, Ouellette W, Koutouzis TK, Cahill DW, Norman AB. Substance P containing polymer implants protect against striatal excitotoxicity. Brain Research. 628: 327-9. PMID 7508810 DOI: 10.1016/0006-8993(93)90974-R  0.374
1992 Tresco PA, Winn SR, Tan S, Jaeger CB, Greene LA, Aebischer P. POLYMER-ENCAPSULATED PC12 CELLS: LONG-TERM SURVIVAL AND ASSOCIATED REDUCTION IN LESION-INDUCED ROTATIONAL BEHAVIOR. Cell Transplantation. 1: 255-264. PMID 28153072  0.701
1992 Valentini RF, Vargo TG, Gardella JA, Aebischer P. Electrically charged polymeric substrates enhance nerve fibre outgrowth In vitro Biomaterials. 13: 183-190. PMID 1567943 DOI: 10.1016/0142-9612(92)90069-Z  0.362
1992 Winn SR, Tresco PA, Zielinski B, Sagen J, Aebischer P. Microencapsulated bovine chromaffin cells in vitro: effect of density and coseeding with a NGF-releasing cell line. Journal of Neural Transplantation & Plasticity. 3: 115-24. PMID 1515479 DOI: 10.1155/Np.1992.115  0.712
1992 Jaeger CB, Aebischer P, Tresco PA, Winn SR, Greene LA. Growth of tumour cell lines in polymer capsules: ultrastructure of encapsulated PC12 cells. Journal of Neurocytology. 21: 469-80. PMID 1500946 DOI: 10.1007/Bf01186951  0.73
1992 Tresco PA, Winn SR, Aebischer P. Polymer encapsulated neurotransmitter secreting cells. Potential treatment for Parkinson's disease. Asaio Journal (American Society For Artificial Internal Organs : 1992). 38: 17-23. PMID 1348191 DOI: 10.1097/00002480-199201000-00006  0.716
1992 Tresco PA, Winn SR, Tan S, Jaeger CB, Greene LA, Aebischer P. Polymer-encapsulated PC12 cells: long-term survival and associated reduction in lesion-induced rotational behavior. Cell Transplantation. 1: 255-64. PMID 1344297 DOI: 10.1177/0963689792001002-307  0.723
1992 Guenard V, Kleitman N, Morrissey T, Bunge R, Aebischer P. Syngeneic Schwann cells derived from adult nerves seeded in semipermeable guidance channels enhance peripheral nerve regeneration The Journal of Neuroscience. 12: 3310-3320. DOI: 10.1523/Jneurosci.12-09-03310.1992  0.356
1991 Aebischer P, Lacy PE, Gerasimidi-Vazeou A, Hauptfeld V. Production of Marked Prolongation of Islet Xenograft Survival (Rat to Mouse) by Local Release of Mouse and Rat Antilymphocyte Sera at Transplant Site Diabetes. 40: 482-485. PMID 2010049 DOI: 10.2337/Diab.40.4.482  0.367
1991 Aebischer P, Wahlberg L, Tresco PA, Winn SR. Macroencapsulation of dopamine-secreting cells by coextrusion with an organic polymer solution. Biomaterials. 12: 50-6. PMID 2009346 DOI: 10.1016/0142-9612(91)90132-T  0.7
1991 Aebischer P, Tresco PA, Winn SR, Greene LA, Jaeger CB. Long-term cross-species brain transplantation of a polymer-encapsulated dopamine-secreting cell line. Experimental Neurology. 111: 269-75. PMID 1999230 DOI: 10.1016/0014-4886(91)90093-R  0.73
1991 Winn SR, Tresco PA, Zielinski B, Greene LA, Jaeger CB, Aebischer P. Behavioral recovery following intrastriatal implantation of microencapsulated PC12 cells. Experimental Neurology. 113: 322-9. PMID 1915723 DOI: 10.1016/0014-4886(91)90022-5  0.727
1991 Jaeger CB, Winn SR, Tresco PA, Aebischer P. Repair of the blood-brain barrier following implantation of polymer capsules. Brain Research. 551: 163-70. PMID 1913150 DOI: 10.1016/0006-8993(91)90929-P  0.634
1991 Guénard V, Valentini RF, Aebischer P. Influence of surface texture of polymeric sheets on peripheral nerve regeneration in a two-compartment guidance system Biomaterials. 12: 259-263. PMID 1878462 DOI: 10.1016/0142-9612(91)90210-2  0.345
1991 Aebischer P, Winn SR, Tresco PA, Jaeger CB, Greene LA. Transplantation of polymer encapsulated neurotransmitter secreting cells: effect of the encapsulation technique. Journal of Biomechanical Engineering. 113: 178-83. PMID 1875690 DOI: 10.1115/1.2891231  0.718
1991 Guénard V, Dinarello CA, Weston PJ, Aebischer P. Peripheral nerve regeneration is impeded by interleukin-1 receptor antagonist released from a polymeric guidance channel. Journal of Neuroscience Research. 29: 396-400. PMID 1833560 DOI: 10.1002/Jnr.490290315  0.308
1991 Fine EG, Valentini RF, Bellamkonda R, Aebischer P. Improved nerve regeneration through piezoelectric vinylidenefluoride-trifluoroethylene copolymer guidance channels Biomaterials. 12: 775-780. PMID 1799653 DOI: 10.1016/0142-9612(91)90029-A  0.551
1991 Christenson L, Wahlberg L, Aebischer P. Mast cells and tissue reaction to intraperitoneally implanted polymer capsules Journal of Biomedical Materials Research. 25: 1119-1131. PMID 1778997 DOI: 10.1002/Jbm.820250906  0.424
1991 Aebischer P, Tresco PA, Sagen J, Winn SR. Transplantation of microencapsulated bovine chromaffin cells reduces lesion-induced rotational asymmetry in rats. Brain Research. 560: 43-9. PMID 1760745 DOI: 10.1016/0006-8993(91)91212-J  0.735
1990 Ip TK, Galletti PM, Aebischer P. Effects of attachment substrates on the growth and differentiation of LLC-PK1 cells. In Vitro Cellular & Developmental Biology : Journal of the Tissue Culture Association. 26: 162-8. PMID 2312499 DOI: 10.1007/Bf02624108  0.35
1990 Jaeger CB, Greene LA, Tresco PA, Winn SR, Aebischer P. Polymer encapsulated dopaminergic cell lines as "alternative neural grafts". Progress in Brain Research. 82: 41-6. PMID 2290954  0.676
1990 Hoffman D, Wahlberg L, Aebischer P. NGF released from a polymer matrix prevents loss of ChAT expression in basal forebrain neurons following a fimbria-fornix lesion. Experimental Neurology. 110: 39-44. PMID 2209780 DOI: 10.1016/0014-4886(90)90049-X  0.441
1990 Jaeger CB, Greene LA, Tresco PA, Winn SR, Aebischer P. Polymer encapsulated dopaminergic cell lines as 'alternative neural grafts' Progress in Brain Research. 82: 41-46. DOI: 10.1016/S0079-6123(08)62588-1  0.715
1989 Aebischer P, Salessiotis AN, Winn SR. Basic fibroblast growth factor released from synthetic guidance channels facilitates peripheral nerve regeneration across long nerve gaps. Journal of Neuroscience Research. 23: 282-289. PMID 2769793 DOI: 10.1002/Jnr.490230306  0.366
1989 Christenson L, Aebischer P, McMillan P, Galletti PM. Tissue reaction to intraperitoneal polymer implants: species difference and effects of corticoid and doxorubicin. Journal of Biomedical Materials Research. 23: 705-18. PMID 2661559 DOI: 10.1002/Jbm.820230704  0.366
1989 Winn SR, Wahlberg L, Tresco PA, Aebischer P. An encapsulated dopamine-releasing polymer alleviates experimental parkinsonism in rats. Experimental Neurology. 105: 244-50. PMID 2504616 DOI: 10.1016/0014-4886(89)90126-X  0.668
1989 Winn SR, Aebischer P, Galletti PM. Brain tissue reaction to permselective polymer capsules. Journal of Biomedical Materials Research. 23: 31-44. PMID 2468675 DOI: 10.1002/Jbm.820230104  0.427
1989 Aebischer P, Guenard V, Brace S. Peripheral nerve regeneration through blind-ended semipermeable guidance channels: effect of the molecular weight cutoff The Journal of Neuroscience. 9: 3590-3595. DOI: 10.1523/Jneurosci.09-10-03590.1989  0.318
1988 Aebischer P, Winn SR, Galletti PM. Transplantation of neural tissue in polymer capsules. Brain Research. 448: 364-8. PMID 3378159 DOI: 10.1016/0006-8993(88)91278-4  0.384
1988 Aebischer P, Goddard MB, Sasken HF, Hunter TJ, Galletti PM. Tissue reaction to fabrics coated with turbostratic carbon: subcutaneous versus vascular implants. Biomaterials. 9: 80-85. PMID 2964876 DOI: 10.1016/0142-9612(88)90075-0  0.334
1988 Galletti PM, Aebischer P, Sasken HF, Goddard MB, Chiu T. Experience with fully bioresorbable aortic grafts in the dog. Surgery. 103: 231-241. DOI: 10.5555/Uri:Pii:0039606088902279  0.386
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