| Year |
Citation |
Score |
| 2021 |
Jensen RK, Bajic G, Sen M, Springer TA, Vorup-Jensen T, Andersen GR. Complement Receptor 3 Forms a Compact High-Affinity Complex with iC3b. Journal of Immunology (Baltimore, Md. : 1950). PMID 34117107 DOI: 10.4049/jimmunol.2001208 |
0.61 |
|
| 2020 |
Klug D, Goellner S, Kehrer J, Sattler J, Strauss L, Singer M, Lu C, Springer TA, Frischknecht F. Evolutionarily distant I domains can functionally replace the essential ligand-binding domain of TRAP. Elife. 9. PMID 32648541 DOI: 10.7554/eLife.57572 |
0.394 |
|
| 2020 |
Klug D, Goellner S, Kehrer J, Sattler J, Strauss L, Singer M, Lu C, Springer TA, Frischknecht F. Author response: Evolutionarily distant I domains can functionally replace the essential ligand-binding domain of Plasmodium TRAP Elife. DOI: 10.7554/Elife.57572.Sa2 |
0.37 |
|
| 2020 |
Jo MH, Li J, Springer TA, Ha T. Integrin-Dependent Difference in Cell Adhesion and Force Exertion Biophysical Journal. 118: 96a. DOI: 10.1016/J.Bpj.2019.11.686 |
0.333 |
|
| 2019 |
Wang J, Su Y, Iacob RE, Engen JR, Springer TA. General structural features that regulate integrin affinity revealed by atypical αVβ8. Nature Communications. 10: 5481. PMID 31792290 DOI: 10.1038/S41467-019-13248-5 |
0.365 |
|
| 2019 |
Buß M, Tegtmeyer N, Schnieder J, Dong X, Li J, Springer TA, Backert S, Niemann HH. Specific high affinity interaction of Helicobacter pylori CagL with integrin α β promotes type IV secretion of CagA into human cells. The Febs Journal. PMID 31197920 DOI: 10.1111/febs.14962 |
0.301 |
|
| 2019 |
Jiang Y, Fu H, Springer TA, Wong WP. Electrostatic Steering Enables Flow-Activated von Willebrand Factor to Bind Platelet Glycoprotein, Revealed by Single-Molecule Stretching and Imaging. Journal of Molecular Biology. PMID 30797858 DOI: 10.1016/J.Jmb.2019.02.014 |
0.345 |
|
| 2018 |
Beilin C, Choudhuri K, Bouma G, Malinova D, Llodra J, Stokes DL, Shimaoka M, Springer TA, Dustin ML, Thrasher AJ, Burns SO. Dendritic cell-expressed common gamma-chain recruits IL-15 for trans-presentation at the murine immunological synapse. Wellcome Open Research. 3: 84. PMID 30483599 DOI: 10.12688/wellcomeopenres.14493.2 |
0.428 |
|
| 2018 |
Sen M, Koksal AC, Yuki K, Wang J, Springer TA. Ligand and cation-induced structural alterations of the leukocyte integrin LFA-1. The Journal of Biological Chemistry. PMID 29507098 DOI: 10.1074/Jbc.Ra117.000710 |
0.683 |
|
| 2018 |
Moore TI, Aaron J, Chew TL, Springer TA. Measuring Integrin Conformational Change on the Cell Surface with Super-Resolution Microscopy. Cell Reports. 22: 1903-1912. PMID 29444440 DOI: 10.1016/J.Celrep.2018.01.062 |
0.359 |
|
| 2018 |
Dong X, Zhao B, Lin FY, Lu C, Rogers BN, Springer TA. High integrin αVβ6 affinity reached by hybrid domain deletion slows ligand-binding on-rate. Proceedings of the National Academy of Sciences of the United States of America. PMID 29378937 DOI: 10.1073/pnas.1718662115 |
0.426 |
|
| 2017 |
Nordenfelt P, Moore TI, Mehta SB, Kalappurakkal JM, Swaminathan V, Koga N, Lambert TJ, Baker D, Waters JC, Oldenbourg R, Tani T, Mayor S, Waterman CM, Springer TA. Direction of actin flow dictates integrin LFA-1 orientation during leukocyte migration. Nature Communications. 8: 2047. PMID 29229906 DOI: 10.1038/S41467-017-01848-Y |
0.802 |
|
| 2017 |
Li J, Springer TA. Energy landscape differences among integrins establish the framework for understanding activation. The Journal of Cell Biology. PMID 29122968 DOI: 10.1083/jcb.201701169 |
0.436 |
|
| 2017 |
Zhao B, Xu S, Dong X, Lu C, Springer TA. Prodomain-Growth Factor Swapping in the Structure of pro-TGF-β1. The Journal of Biological Chemistry. PMID 29109152 DOI: 10.1074/jbc.M117.809657 |
0.313 |
|
| 2017 |
Swaminathan V, Kalappurakkal JM, Mehta SB, Nordenfelt P, Moore TI, Koga N, Baker DA, Oldenbourg R, Tani T, Mayor S, Springer TA, Waterman CM. Actin retrograde flow actively aligns and orients ligand-engaged integrins in focal adhesions. Proceedings of the National Academy of Sciences of the United States of America. 114: 10648-10653. PMID 29073038 DOI: 10.1073/Pnas.1701136114 |
0.796 |
|
| 2017 |
Fu H, Jiang Y, Yang D, Scheiflinger F, Wong WP, Springer TA. Flow-induced elongation of von Willebrand factor precedes tension-dependent activation. Nature Communications. 8: 324. PMID 28831047 DOI: 10.1038/S41467-017-00230-2 |
0.349 |
|
| 2017 |
Kotecha A, Wang Q, Dong X, Ilca SL, Ondiviela M, Zihe R, Seago J, Charleston B, Fry EE, Abrescia NGA, Springer TA, Huiskonen JT, Stuart DI. Rules of engagement between αvβ6 integrin and foot-and-mouth disease virus. Nature Communications. 8: 15408. PMID 28534487 DOI: 10.1038/ncomms15408 |
0.347 |
|
| 2017 |
Wang J, Dong X, Zhao B, Li J, Lu C, Springer TA. Atypical interactions of integrin αVβ8 with pro-TGF-β1. Proceedings of the National Academy of Sciences of the United States of America. PMID 28484027 DOI: 10.1073/pnas.1705129114 |
0.33 |
|
| 2017 |
Li J, Springer TA. Integrin extension enables ultrasensitive regulation by cytoskeletal force. Proceedings of the National Academy of Sciences of the United States of America. PMID 28416675 DOI: 10.1073/pnas.1704171114 |
0.385 |
|
| 2017 |
Xu S, Wang J, Wang JH, Springer TA. Distinct recognition of complement iC3b by integrins αXβ2 and αMβ2. Proceedings of the National Academy of Sciences of the United States of America. PMID 28292891 DOI: 10.1073/Pnas.1620881114 |
0.47 |
|
| 2017 |
Li J, Su Y, Xia W, Qin Y, Humphries MJ, Vestweber D, Cabañas C, Lu C, Springer TA. Conformational equilibria and intrinsic affinities define integrin activation. The Embo Journal. PMID 28122868 DOI: 10.15252/Embj.201695803 |
0.408 |
|
| 2017 |
Dong X, Zhao B, Iacob RE, Zhu J, Koksal AC, Lu C, Engen JR, Springer TA. Force interacts with macromolecular structure in activation of TGF-β. Nature. PMID 28117447 DOI: 10.1038/Nature21035 |
0.343 |
|
| 2016 |
Nordenfelt P, Elliott HL, Springer TA. Coordinated integrin activation by actin-dependent force during T-cell migration. Nature Communications. 7: 13119. PMID 27721490 DOI: 10.1038/ncomms13119 |
0.369 |
|
| 2016 |
Hinck AP, Mueller TD, Springer TA. Structural Biology and Evolution of the TGF-β Family. Cold Spring Harbor Perspectives in Biology. PMID 27638177 DOI: 10.1101/Cshperspect.A022103 |
0.323 |
|
| 2016 |
Su Y, Xia W, Li J, Walz T, Humphries MJ, Vestweber D, Cabañas C, Lu C, Springer TA. Relating conformation to function in integrin α5β1. Proceedings of the National Academy of Sciences of the United States of America. PMID 27317747 DOI: 10.1073/Pnas.1605074113 |
0.409 |
|
| 2016 |
Springer TA, Sen M. Leukocyte integrin αLβ2 headpiece structures: The αI domain, the pocket for the internal ligand, and concerted movements of its loops. Proceedings of the National Academy of Sciences of the United States of America. PMID 26936951 DOI: 10.1073/Pnas.1601379113 |
0.649 |
|
| 2016 |
Hudson N, Kim J, Springer TA. On-Rate Switching under Force Increases the Binding of von Willebrand Factor A1 to GPIbα Biophysical Journal. 110: 636a. DOI: 10.1016/J.Bpj.2015.11.3406 |
0.712 |
|
| 2016 |
Fu H, Jiang Y, Yang D, Wong WP, Springer TA. Single-Molecule Activation by Flow: Force-Induced Conformational Transitions Regulate the Ligand Binding Affinity of a Large, Polymeric Mechanosensor Protein Biophysical Journal. 110: 348a. DOI: 10.1016/J.Bpj.2015.11.1873 |
0.374 |
|
| 2015 |
Lin FY, Zhu J, Eng ET, Hudson NE, Springer TA. β-subunit Binding is Sufficient for Ligands to open the Integrin αIIbβ3 Headpiece. The Journal of Biological Chemistry. PMID 26631735 DOI: 10.1074/Jbc.M115.705624 |
0.382 |
|
| 2015 |
Bury L, Falcinelli E, Chiasserini D, Springer TA, Italiano JE, Gresele P. Cytoskeletal perturbation leads to platelet dysfunction and thrombocytopenia in Glanzmann variants. Haematologica. PMID 26452979 DOI: 10.3324/haematol.2015.130849 |
0.306 |
|
| 2015 |
Deforche L, Roose E, Vandenbulcke A, Vandeputte N, Feys HB, Springer TA, Mi LZ, Muia J, Sadler JE, Soejima K, Rottensteiner H, Deckmyn H, De Meyer SF, Vanhoorelbeke K. Linker regions and flexibility around the metalloprotease domain account for conformational activation of ADAMTS-13. Journal of Thrombosis and Haemostasis : Jth. 13: 2063-75. PMID 26391536 DOI: 10.1111/jth.13149 |
0.373 |
|
| 2015 |
Zhu J, Zhu J, Bougie DW, Aster RH, Springer TA. Structural basis for quinine-dependent antibody binding to platelet integrin αIIbβ3. Blood. 126: 2138-45. PMID 26282540 DOI: 10.1182/Blood-2015-04-639351 |
0.352 |
|
| 2015 |
Kim J, Hudson NE, Springer TA. Force-induced on-rate switching and modulation by mutations in gain-of-function von Willebrand diseases. Proceedings of the National Academy of Sciences of the United States of America. 112: 4648-53. PMID 25810255 DOI: 10.1073/Pnas.1501689112 |
0.693 |
|
| 2015 |
Lin L, Liu L, Zhao B, Xie R, Lin W, Li H, Li Y, Shi M, Chen YG, Springer TA, Chen X. Carbon nanotube-assisted optical activation of TGF-β signalling by near-infrared light. Nature Nanotechnology. 10: 465-71. PMID 25775150 DOI: 10.1038/Nnano.2015.28 |
0.673 |
|
| 2015 |
Mi LZ, Brown CT, Gao Y, Tian Y, Le VQ, Walz T, Springer TA. Structure of bone morphogenetic protein 9 procomplex. Proceedings of the National Academy of Sciences of the United States of America. 112: 3710-5. PMID 25751889 DOI: 10.1073/Pnas.1501303112 |
0.309 |
|
| 2014 |
Xia W, Springer TA. Metal ion and ligand binding of integrin α5β1. Proceedings of the National Academy of Sciences of the United States of America. 111: 17863-8. PMID 25475857 DOI: 10.1073/pnas.1420645111 |
0.391 |
|
| 2014 |
Dong X, Hudson NE, Lu C, Springer TA. Structural determinants of integrin β-subunit specificity for latent TGF-β. Nature Structural & Molecular Biology. 21: 1091-6. PMID 25383667 DOI: 10.1038/Nsmb.2905 |
0.346 |
|
| 2014 |
Springer TA. von Willebrand factor, Jedi knight of the bloodstream. Blood. 124: 1412-25. PMID 24928861 DOI: 10.1182/blood-2014-05-378638 |
0.324 |
|
| 2014 |
Song G, Springer TA. Structures of the Toxoplasma gliding motility adhesin. Proceedings of the National Academy of Sciences of the United States of America. 111: 4862-7. PMID 24639528 DOI: 10.1073/pnas.1403059111 |
0.368 |
|
| 2014 |
Kollmann CS, Bai X, Tsai CH, Yang H, Lind KE, Skinner SR, Zhu Z, Israel DI, Cuozzo JW, Morgan BA, Yuki K, Xie C, Springer TA, Shimaoka M, Evindar G. Application of encoded library technology (ELT) to a protein-protein interaction target: discovery of a potent class of integrin lymphocyte function-associated antigen 1 (LFA-1) antagonists. Bioorganic & Medicinal Chemistry. 22: 2353-65. PMID 24593905 DOI: 10.1016/J.Bmc.2014.01.050 |
0.355 |
|
| 2014 |
Zhou YF, Springer TA. Highly reinforced structure of a C-terminal dimerization domain in von Willebrand factor. Blood. 123: 1785-93. PMID 24394662 DOI: 10.1182/blood-2013-11-523639 |
0.338 |
|
| 2014 |
Blenner MA, Dong X, Springer TA. Structural basis of regulation of von Willebrand factor binding to glycoprotein Ib. The Journal of Biological Chemistry. 289: 5565-79. PMID 24391089 DOI: 10.1074/Jbc.M113.511220 |
0.68 |
|
| 2014 |
Jiang Y, Fu H, Yang D, Springer TA, Wong WP. Single-Molecule Imaging of Von Willebrand Factor Activation by Flow Biophysical Journal. 106: 194a. DOI: 10.1016/J.Bpj.2013.11.1150 |
0.323 |
|
| 2013 |
Sen M, Yuki K, Springer TA. An internal ligand-bound, metastable state of a leukocyte integrin, αXβ2. The Journal of Cell Biology. 203: 629-42. PMID 24385486 DOI: 10.1083/Jcb.201308083 |
0.67 |
|
| 2013 |
Yu Y, Schürpf T, Springer TA. How natalizumab binds and antagonizes α4 integrins. The Journal of Biological Chemistry. 288: 32314-25. PMID 24047894 DOI: 10.1074/jbc.M113.501668 |
0.457 |
|
| 2013 |
Zhu J, Zhu J, Springer TA. Complete integrin headpiece opening in eight steps. The Journal of Cell Biology. 201: 1053-68. PMID 23798730 DOI: 10.1083/Jcb.201212037 |
0.389 |
|
| 2013 |
Xu AJ, Springer TA. Mechanisms by which von Willebrand disease mutations destabilize the A2 domain. The Journal of Biological Chemistry. 288: 6317-24. PMID 23322777 DOI: 10.1074/Jbc.M112.422618 |
0.308 |
|
| 2013 |
Yu Y, Zhu J, Huang PS, Wang JH, Pullen N, Springer TA. Domain 1 of mucosal addressin cell adhesion molecule has an I1-set fold and a flexible integrin-binding loop. The Journal of Biological Chemistry. 288: 6284-94. PMID 23297416 DOI: 10.1074/Jbc.M112.413153 |
0.537 |
|
| 2013 |
Sen M, Yuki K, Springer TA. An internal ligand-bound, metastable state of a leukocyte integrin, alpha X beta 2. Journal of Cell Biology. 203: 629-642. DOI: 10.2210/Pdb4Neh/Pdb |
0.629 |
|
| 2012 |
Song G, Koksal AC, Lu C, Springer TA. Shape change in the receptor for gliding motility in Plasmodium sporozoites. Proceedings of the National Academy of Sciences of the United States of America. 109: 21420-5. PMID 23236185 DOI: 10.1073/pnas.1218581109 |
0.396 |
|
| 2012 |
Dong X, Mi LZ, Zhu J, Wang W, Hu P, Luo BH, Springer TA. α(V)β(3) integrin crystal structures and their functional implications. Biochemistry. 51: 8814-28. PMID 23106217 DOI: 10.1021/Bi300734N |
0.352 |
|
| 2012 |
Lu C, Mi LZ, Schürpf T, Walz T, Springer TA. Mechanisms for kinase-mediated dimerization of the epidermal growth factor receptor. The Journal of Biological Chemistry. 287: 38244-53. PMID 22988250 DOI: 10.1074/Jbc.M112.414391 |
0.336 |
|
| 2012 |
Kang S, Kim CU, Gu X, Owens RM, van Rijn SJ, Boonyaleepun V, Mao Y, Springer TA, Jin MM. Complex structure of engineered modular domains defining molecular interaction between ICAM-1 and integrin LFA-1. Plos One. 7: e44124. PMID 22956999 DOI: 10.1371/Journal.Pone.0044124 |
0.361 |
|
| 2012 |
Schürpf T, Chen Q, Liu JH, Wang R, Springer TA, Wang JH. The RGD finger of Del-1 is a unique structural feature critical for integrin binding. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 3412-20. PMID 22601780 DOI: 10.1096/Fj.11-202036 |
0.504 |
|
| 2012 |
Doud MB, Koksal AC, Mi LZ, Song G, Lu C, Springer TA. Unexpected fold in the circumsporozoite protein target of malaria vaccines. Proceedings of the National Academy of Sciences of the United States of America. 109: 7817-22. PMID 22547819 DOI: 10.1073/Pnas.1205737109 |
0.335 |
|
| 2012 |
Zhou YF, Eng ET, Zhu J, Lu C, Walz T, Springer TA. Sequence and structure relationships within von Willebrand factor. Blood. 120: 449-58. PMID 22490677 DOI: 10.1182/Blood-2012-01-405134 |
0.339 |
|
| 2012 |
Sage PT, Varghese LM, Martinelli R, Sciuto TE, Kamei M, Dvorak AM, Springer TA, Sharpe AH, Carman CV. Antigen recognition is facilitated by invadosome-like protrusions formed by memory/effector T cells. Journal of Immunology (Baltimore, Md. : 1950). 188: 3686-99. PMID 22442443 DOI: 10.4049/Jimmunol.1102594 |
0.346 |
|
| 2012 |
Zhu J, Choi WS, McCoy JG, Negri A, Zhu J, Naini S, Li J, Shen M, Huang W, Bougie D, Rasmussen M, Aster R, Thomas CJ, Filizola M, Springer TA, et al. Structure-guided design of a high-affinity platelet integrin αIIbβ3 receptor antagonist that disrupts Mg²⺠binding to the MIDAS. Science Translational Medicine. 4: 125ra32. PMID 22422993 DOI: 10.1126/Scitranslmed.3003576 |
0.386 |
|
| 2012 |
Chen X, Yu Y, Mi LZ, Walz T, Springer TA. Molecular basis for complement recognition by integrin αXβ2. Proceedings of the National Academy of Sciences of the United States of America. 109: 4586-91. PMID 22393018 DOI: 10.1073/Pnas.1202051109 |
0.478 |
|
| 2012 |
Wang R, Zhu J, Dong X, Shi M, Lu C, Springer TA. GARP regulates the bioavailability and activation of TGFβ. Molecular Biology of the Cell. 23: 1129-39. PMID 22278742 DOI: 10.1091/Mbc.E11-12-1018 |
0.353 |
|
| 2012 |
Yu Y, Zhu J, Mi LZ, Walz T, Sun H, Chen J, Springer TA. Structural specializations of α(4)β(7), an integrin that mediates rolling adhesion. The Journal of Cell Biology. 196: 131-46. PMID 22232704 DOI: 10.1083/Jcb.201110023 |
0.439 |
|
| 2012 |
Springer TA, Dustin ML. Integrin inside-out signaling and the immunological synapse. Current Opinion in Cell Biology. 24: 107-15. PMID 22129583 DOI: 10.1016/J.Ceb.2011.10.004 |
0.6 |
|
| 2012 |
Dong X, Mi LZ, Zhu J, Wang W, Hu P, Luo BH, Springer TA. Alpha V Beta 3 Integrin Crystal Structures and their Functional Implications Biochemistry. 51: 8814-8828. DOI: 10.2210/Pdb4G1E/Pdb |
0.312 |
|
| 2012 |
Springer TA, Kim J. Activation of A1 Domain Adhesiveness in von Willebrand Factor by Elongational Force Blood. 120: SCI-16-SCI-16. DOI: 10.1182/BLOOD.V120.21.SCI-16.SCI-16 |
0.711 |
|
| 2011 |
Weitz-Schmidt G, Schürpf T, Springer TA. The C-terminal αI domain linker as a critical structural element in the conformational activation of αI integrins. The Journal of Biological Chemistry. 286: 42115-22. PMID 21965670 DOI: 10.1074/jbc.M111.282830 |
0.362 |
|
| 2011 |
Schürpf T, Springer TA. Regulation of integrin affinity on cell surfaces. The Embo Journal. 30: 4712-27. PMID 21946563 DOI: 10.1038/emboj.2011.333 |
0.478 |
|
| 2011 |
Zhou YF, Eng ET, Nishida N, Lu C, Walz T, Springer TA. A pH-regulated dimeric bouquet in the structure of von Willebrand factor. The Embo Journal. 30: 4098-111. PMID 21857647 DOI: 10.1038/Emboj.2011.297 |
0.306 |
|
| 2011 |
Eng ET, Smagghe BJ, Walz T, Springer TA. Intact alphaIIbbeta3 integrin is extended after activation as measured by solution X-ray scattering and electron microscopy. The Journal of Biological Chemistry. 286: 35218-26. PMID 21832081 DOI: 10.1074/Jbc.M111.275107 |
0.353 |
|
| 2011 |
Mi LZ, Lu C, Li Z, Nishida N, Walz T, Springer TA. Simultaneous visualization of the extracellular and cytoplasmic domains of the epidermal growth factor receptor. Nature Structural & Molecular Biology. 18: 984-9. PMID 21822280 DOI: 10.1038/Nsmb.2092 |
0.338 |
|
| 2011 |
Springer TA. Biology and physics of von Willebrand factor concatamers. Journal of Thrombosis and Haemostasis : Jth. 9: 130-43. PMID 21781248 DOI: 10.1111/j.1538-7836.2011.04320.x |
0.353 |
|
| 2011 |
Shi M, Zhu J, Wang R, Chen X, Mi L, Walz T, Springer TA. Latent TGF-β structure and activation. Nature. 474: 343-9. PMID 21677751 DOI: 10.1038/Nature10152 |
0.462 |
|
| 2011 |
Rothlein R, Dustin ML, Marlin SD, Springer TA. A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1. J. Immunol. 1986. 137: 1270-1274. Journal of Immunology (Baltimore, Md. : 1950). 186: 5034-8. PMID 21505215 |
0.44 |
|
| 2011 |
Dustin ML, Rothlein R, Bhan AK, Dinarello CA, Springer TA. Induction by IL 1 and interferon-γ: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1). J. Immunol. 1986. 137: 245-254. Journal of Immunology (Baltimore, Md. : 1950). 186: 5024-33. PMID 21505214 |
0.376 |
|
| 2011 |
Zhou M, Dong X, Baldauf C, Chen H, Zhou Y, Springer TA, Luo X, Zhong C, Gräter F, Ding J. A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13. Blood. 117: 4623-31. PMID 21385852 DOI: 10.1182/Blood-2010-11-321596 |
0.324 |
|
| 2011 |
Wang W, Zhu J, Springer TA, Luo BH. Tests of integrin transmembrane domain homo-oligomerization during integrin ligand binding and signaling. The Journal of Biological Chemistry. 286: 1860-7. PMID 21081497 DOI: 10.1074/Jbc.M110.193797 |
0.411 |
|
| 2011 |
Zhu J, Choi W, McCoy JG, Negri A, Zhu J, Naini S, Li J, Shen M, Huang W, Thomas CJ, Filizola M, Springer T, Coller BS. Structure-Guided Design of A Novel High Affinity Integrin αIIbβ3 Receptor Antagonist (RUC-2) That Displaces Mg2+ From the β3 MIDAS, Blood. 118: 3255-3255. DOI: 10.1182/Blood.V118.21.3255.3255 |
0.378 |
|
| 2010 |
Pan Y, Zhang K, Qi J, Yue J, Springer TA, Chen J. Cation-pi interaction regulates ligand-binding affinity and signaling of integrin alpha4beta7. Proceedings of the National Academy of Sciences of the United States of America. 107: 21388-93. PMID 21098296 DOI: 10.1073/pnas.1015487107 |
0.389 |
|
| 2010 |
Lu C, Mi LZ, Grey MJ, Zhu J, Graef E, Yokoyama S, Springer TA. Structural evidence for loose linkage between ligand binding and kinase activation in the epidermal growth factor receptor. Molecular and Cellular Biology. 30: 5432-43. PMID 20837704 DOI: 10.1128/Mcb.00742-10 |
0.369 |
|
| 2010 |
Kim J, Zhang CZ, Zhang X, Springer TA. A mechanically stabilized receptor-ligand flex-bond important in the vasculature. Nature. 466: 992-5. PMID 20725043 DOI: 10.1038/nature09295 |
0.715 |
|
| 2010 |
Zhu J, Zhu J, Negri A, Provasi D, Filizola M, Coller BS, Springer TA. Closed headpiece of integrin αIIbβ3 and its complex with an αIIbβ3-specific antagonist that does not induce opening. Blood. 116: 5050-9. PMID 20679525 DOI: 10.1182/Blood-2010-04-281154 |
0.404 |
|
| 2010 |
Chen X, Xie C, Nishida N, Li Z, Walz T, Springer TA. Requirement of open headpiece conformation for activation of leukocyte integrin alphaXbeta2. Proceedings of the National Academy of Sciences of the United States of America. 107: 14727-32. PMID 20679211 DOI: 10.1073/Pnas.1008663107 |
0.487 |
|
| 2010 |
Smagghe BJ, Huang PS, Ban YE, Baker D, Springer TA. Modulation of integrin activation by an entropic spring in the {beta}-knee. The Journal of Biological Chemistry. 285: 32954-66. PMID 20670939 DOI: 10.1074/Jbc.M110.145177 |
0.378 |
|
| 2010 |
Owens RM, Gu X, Shin M, Springer TA, Jin MM. Engineering of single Ig superfamily domain of intercellular adhesion molecule 1 (ICAM-1) for native fold and function. The Journal of Biological Chemistry. 285: 15906-15. PMID 20304924 DOI: 10.1074/Jbc.M110.104349 |
0.403 |
|
| 2010 |
Xie C, Zhu J, Chen X, Mi L, Nishida N, Springer TA. Structure of an integrin with an alphaI domain, complement receptor type 4. The Embo Journal. 29: 666-79. PMID 20033057 DOI: 10.1038/Emboj.2009.367 |
0.515 |
|
| 2010 |
Zhu J, Negri A, Provasi D, Filizola M, Coller BS, Springer TA. Closed headpiece of integrin {alpha}IIb{beta}3 and its complex with an {alpha}IIb{beta}3-specific antagonist that does not induce opening. Blood. 116: 5050-5059. DOI: 10.2210/Pdb3Nid/Pdb |
0.366 |
|
| 2010 |
Negri A, Provasi D, Zhu J, Zhu J, Coller BS, Springer TA, Filizola M. Computational Prediction and Experimental Validation of a Novel Binding Site for Platelet Integrin AlphaIIb-Beta3 Biophysical Journal. 98: 40a. DOI: 10.1016/J.Bpj.2009.12.229 |
0.398 |
|
| 2009 |
Zhang H, Liu JH, Yang W, Springer T, Shimaoka M, Wang JH. Structural basis of activation-dependent binding of ligand-mimetic antibody AL-57 to integrin LFA-1. Proceedings of the National Academy of Sciences of the United States of America. 106: 18345-50. PMID 19805116 DOI: 10.1073/Pnas.0909301106 |
0.515 |
|
| 2009 |
Zhang X, Halvorsen K, Zhang CZ, Wong WP, Springer TA. Mechanoenzymatic cleavage of the ultralarge vascular protein von Willebrand factor. Science (New York, N.Y.). 324: 1330-4. PMID 19498171 DOI: 10.1126/Science.1170905 |
0.311 |
|
| 2009 |
Zhang Q, Zhou YF, Zhang CZ, Zhang X, Lu C, Springer TA. Structural specializations of A2, a force-sensing domain in the ultralarge vascular protein von Willebrand factor. Proceedings of the National Academy of Sciences of the United States of America. 106: 9226-31. PMID 19470641 DOI: 10.1073/pnas.0903679106 |
0.365 |
|
| 2009 |
Zhu J, Luo BH, Barth P, Schonbrun J, Baker D, Springer TA. The structure of a receptor with two associating transmembrane domains on the cell surface: integrin alphaIIbbeta3. Molecular Cell. 34: 234-49. PMID 19394300 DOI: 10.1016/J.Molcel.2009.02.022 |
0.415 |
|
| 2009 |
Vanhoorelbeke K, De Meyer SF, Pareyn I, Melchior C, Plançon S, Margue C, Pradier O, Fondu P, Kieffer N, Springer TA, Deckmyn H. The novel S527F mutation in the integrin beta3 chain induces a high affinity alphaIIbbeta3 receptor by hindering adoption of the bent conformation. The Journal of Biological Chemistry. 284: 14914-20. PMID 19329429 DOI: 10.1074/jbc.M809167200 |
0.38 |
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| 2009 |
Waldron TT, Springer TA. Transmission of allostery through the lectin domain in selectin-mediated cell adhesion. Proceedings of the National Academy of Sciences of the United States of America. 106: 85-90. PMID 19118202 DOI: 10.1073/pnas.0810620105 |
0.401 |
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| 2009 |
Springer TA. Structural basis for selectin mechanochemistry. Proceedings of the National Academy of Sciences of the United States of America. 106: 91-6. PMID 19118197 DOI: 10.1073/pnas.0810784105 |
0.433 |
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| 2009 |
Luo BH, Karanicolas J, Harmacek LD, Baker D, Springer TA. Rationally designed integrin beta3 mutants stabilized in the high affinity conformation. The Journal of Biological Chemistry. 284: 3917-24. PMID 19019827 DOI: 10.1074/Jbc.M806312200 |
0.418 |
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| 2009 |
Zhu J, Zhu J, Negri A, Provasi D, Filizola M, Coller BS, Springer TA. Structural, Functional, and Dynamic Characterization of the Binding Site of RUC-1, a Novel αIIb-Specific Inhibitor of Integrin αIIbβ3. Blood. 114: 151-151. DOI: 10.1182/Blood.V114.22.151.151 |
0.39 |
|
| 2009 |
Zhang X, Halvorsen K, Wong WP, Springer TA. Unfolding, refolding and proteolysis of the von Willebrand Factor A2 domain under tensile force Biophysical Journal. 96: 37a. DOI: 10.1016/J.Bpj.2008.12.083 |
0.303 |
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| 2008 |
Zhu J, Luo BH, Xiao T, Zhang C, Nishida N, Springer TA. Structure of a complete integrin ectodomain in a physiologic resting state and activation and deactivation by applied forces. Molecular Cell. 32: 849-61. PMID 19111664 DOI: 10.1016/J.Molcel.2008.11.018 |
0.698 |
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| 2008 |
Mi LZ, Grey MJ, Nishida N, Walz T, Lu C, Springer TA. Functional and structural stability of the epidermal growth factor receptor in detergent micelles and phospholipid nanodiscs. Biochemistry. 47: 10314-23. PMID 18771282 DOI: 10.1021/Bi801006S |
0.352 |
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| 2008 |
Springer TA, Zhu J, Xiao T. Structural basis for distinctive recognition of fibrinogen gammaC peptide by the platelet integrin alphaIIbbeta3. The Journal of Cell Biology. 182: 791-800. PMID 18710925 DOI: 10.1083/Jcb.200801146 |
0.687 |
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| 2008 |
Zhang H, Casasnovas JM, Jin M, Liu JH, Gahmberg CG, Springer TA, Wang JH. An unusual allosteric mobility of the C-terminal helix of a high-affinity alphaL integrin I domain variant bound to ICAM-5. Molecular Cell. 31: 432-7. PMID 18691975 DOI: 10.1016/J.Molcel.2008.06.022 |
0.517 |
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| 2008 |
Carman CV, Springer TA. Trans-cellular migration: cell-cell contacts get intimate. Current Opinion in Cell Biology. 20: 533-40. PMID 18595683 DOI: 10.1016/j.ceb.2008.05.007 |
0.328 |
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| 2008 |
Morin NA, Oakes PW, Hyun YM, Lee D, Chin YE, Chin EY, King MR, Springer TA, Shimaoka M, Tang JX, Reichner JS, Kim M. Nonmuscle myosin heavy chain IIA mediates integrin LFA-1 de-adhesion during T lymphocyte migration. The Journal of Experimental Medicine. 205: 195-205. PMID 18195072 DOI: 10.1084/Jem.20071543 |
0.374 |
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| 2008 |
Milstein C, Galfre G, Secher DS, Springer T. Monoclonal Antibodies and Cell Surface Antigens Human Genetics: Possibilities and Realities. 251-281. DOI: 10.1002/9780470720486.ch11 |
0.462 |
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| 2007 |
Chen X, Kim TD, Carman CV, Mi LZ, Song G, Springer TA. Structural plasticity in Ig superfamily domain 4 of ICAM-1 mediates cell surface dimerization. Proceedings of the National Academy of Sciences of the United States of America. 104: 15358-63. PMID 17881562 DOI: 10.1073/Pnas.0707406104 |
0.375 |
|
| 2007 |
Bonasio R, Carman CV, Kim E, Sage PT, Love KR, Mempel TR, Springer TA, von Andrian UH. Specific and covalent labeling of a membrane protein with organic fluorochromes and quantum dots. Proceedings of the National Academy of Sciences of the United States of America. 104: 14753-8. PMID 17785425 DOI: 10.1073/Pnas.0705201104 |
0.307 |
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| 2007 |
Vorup-Jensen T, Waldron TT, Astrof N, Shimaoka M, Springer TA. The connection between metal ion affinity and ligand affinity in integrin I domains. Biochimica Et Biophysica Acta. 1774: 1148-55. PMID 17702677 DOI: 10.1016/j.bbapap.2007.06.014 |
0.394 |
|
| 2007 |
Vorup-Jensen T, Chi L, Gjelstrup LC, Jensen UB, Jewett CA, Xie C, Shimaoka M, Linhardt RJ, Springer TA. Binding between the integrin alphaXbeta2 (CD11c/CD18) and heparin. The Journal of Biological Chemistry. 282: 30869-77. PMID 17699512 DOI: 10.1074/Jbc.M706114200 |
0.441 |
|
| 2007 |
Zhu J, Carman CV, Kim M, Shimaoka M, Springer TA, Luo BH. Requirement of alpha and beta subunit transmembrane helix separation for integrin outside-in signaling. Blood. 110: 2475-83. PMID 17615290 DOI: 10.1182/Blood-2007-03-080077 |
0.461 |
|
| 2007 |
Carman CV, Sage PT, Sciuto TE, de la Fuente MA, Geha RS, Ochs HD, Dvorak HF, Dvorak AM, Springer TA. Transcellular diapedesis is initiated by invasive podosomes. Immunity. 26: 784-97. PMID 17570692 DOI: 10.1016/J.Immuni.2007.04.015 |
0.335 |
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| 2007 |
Zhu J, Boylan B, Luo BH, Newman PJ, Springer TA. Tests of the extension and deadbolt models of integrin activation. The Journal of Biological Chemistry. 282: 11914-20. PMID 17301049 DOI: 10.1074/Jbc.M700249200 |
0.428 |
|
| 2007 |
Luo BH, Carman CV, Springer TA. Structural basis of integrin regulation and signaling. Annual Review of Immunology. 25: 619-47. PMID 17201681 DOI: 10.1146/Annurev.Immunol.25.022106.141618 |
0.456 |
|
| 2006 |
Nishida N, Walz T, Springer TA. Structural transitions of complement component C3 and its activation products. Proceedings of the National Academy of Sciences of the United States of America. 103: 19737-42. PMID 17172439 DOI: 10.1073/Pnas.0609791104 |
0.317 |
|
| 2006 |
Astrof NS, Salas A, Shimaoka M, Chen J, Springer TA. Importance of force linkage in mechanochemistry of adhesion receptors. Biochemistry. 45: 15020-8. PMID 17154539 DOI: 10.1021/bi061566o |
0.436 |
|
| 2006 |
Springer TA. Complement and the multifaceted functions of VWA and integrin I domains. Structure (London, England : 1993). 14: 1611-6. PMID 17098186 DOI: 10.1016/j.str.2006.10.001 |
0.384 |
|
| 2006 |
Nishida N, Xie C, Shimaoka M, Cheng Y, Walz T, Springer TA. Activation of leukocyte beta2 integrins by conversion from bent to extended conformations. Immunity. 25: 583-94. PMID 17045822 DOI: 10.1016/J.Immuni.2006.07.016 |
0.363 |
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| 2006 |
Swers JS, Widom A, Phan U, Springer TA, Wittrup KD. A high affinity human antibody antagonist of P-selectin mediated rolling. Biochemical and Biophysical Research Communications. 350: 508-13. PMID 17027652 DOI: 10.1016/J.Bbrc.2006.08.197 |
0.34 |
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| 2006 |
Yang W, Carman CV, Kim M, Salas A, Shimaoka M, Springer TA. A small molecule agonist of an integrin, alphaLbeta2. The Journal of Biological Chemistry. 281: 37904-12. PMID 17023419 DOI: 10.1074/Jbc.M606888200 |
0.376 |
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| 2006 |
Shimaoka M, Kim M, Cohen EH, Yang W, Astrof N, Peer D, Salas A, Ferrand A, Springer TA. AL-57, a ligand-mimetic antibody to integrin LFA-1, reveals chemokine-induced affinity up-regulation in lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 103: 13991-6. PMID 16963559 DOI: 10.1073/Pnas.0605716103 |
0.436 |
|
| 2006 |
Chen J, Yang W, Kim M, Carman CV, Springer TA. Regulation of outside-in signaling and affinity by the beta2 I domain of integrin alphaLbeta2. Proceedings of the National Academy of Sciences of the United States of America. 103: 13062-7. PMID 16920795 DOI: 10.1073/Pnas.0605666103 |
0.412 |
|
| 2006 |
Luo BH, Springer TA. Integrin structures and conformational signaling. Current Opinion in Cell Biology. 18: 579-86. PMID 16904883 DOI: 10.1016/J.Ceb.2006.08.005 |
0.417 |
|
| 2006 |
Huang L, Shimaoka M, Rondon IJ, Roy I, Chang Q, Po M, Dransfield DT, Ladner RC, Edge AS, Salas A, Wood CR, Springer TA, Cohen EH. Identification and characterization of a human monoclonal antagonistic antibody AL-57 that preferentially binds the high-affinity form of lymphocyte function-associated antigen-1. Journal of Leukocyte Biology. 80: 905-14. PMID 16888085 DOI: 10.1189/jlb.1105649 |
0.438 |
|
| 2006 |
Phan UT, Waldron TT, Springer TA. Remodeling of the lectin-EGF-like domain interface in P- and L-selectin increases adhesiveness and shear resistance under hydrodynamic force. Nature Immunology. 7: 883-9. PMID 16845394 DOI: 10.1038/ni1366 |
0.399 |
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| 2006 |
Jin M, Song G, Carman CV, Kim YS, Astrof NS, Shimaoka M, Wittrup DK, Springer TA. Directed evolution to probe protein allostery and integrin I domains of 200,000-fold higher affinity. Proceedings of the National Academy of Sciences of the United States of America. 103: 5758-63. PMID 16595626 DOI: 10.1073/Pnas.0601164103 |
0.442 |
|
| 2006 |
Salas A, Shimaoka M, Phan U, Kim M, Springer TA. Transition from rolling to firm adhesion can be mimicked by extension of integrin alphaLbeta2 in an intermediate affinity state. The Journal of Biological Chemistry. 281: 10876-82. PMID 16505487 DOI: 10.1074/Jbc.M512472200 |
0.452 |
|
| 2006 |
Song G, Lazar GA, Kortemme T, Shimaoka M, Desjarlais JR, Baker D, Springer TA. Rational design of intercellular adhesion molecule-1 (ICAM-1) variants for antagonizing integrin lymphocyte function-associated antigen-1-dependent adhesion. The Journal of Biological Chemistry. 281: 5042-9. PMID 16354667 DOI: 10.1074/Jbc.M510454200 |
0.443 |
|
| 2005 |
Zhang F, Marcus WD, Goyal NH, Selvaraj P, Springer TA, Zhu C. Two-dimensional kinetics regulation of alphaLbeta2-ICAM-1 interaction by conformational changes of the alphaL-inserted domain. The Journal of Biological Chemistry. 280: 42207-18. PMID 16234238 DOI: 10.1074/Jbc.M510407200 |
0.411 |
|
| 2005 |
Luo BH, Carman CV, Takagi J, Springer TA. Disrupting integrin transmembrane domain heterodimerization increases ligand binding affinity, not valency or clustering. Proceedings of the National Academy of Sciences of the United States of America. 102: 3679-84. PMID 15738420 DOI: 10.1073/Pnas.0409440102 |
0.433 |
|
| 2005 |
Song G, Yang Y, Liu JH, Casasnovas JM, Shimaoka M, Springer TA, Wang JH. An atomic resolution view of ICAM recognition in a complex between the binding domains of ICAM-3 and integrin alphaLbeta2. Proceedings of the National Academy of Sciences of the United States of America. 102: 3366-71. PMID 15728350 DOI: 10.1073/Pnas.0500200102 |
0.5 |
|
| 2005 |
Vorup-Jensen T, Carman CV, Shimaoka M, Schuck P, Svitel J, Springer TA. Exposure of acidic residues as a danger signal for recognition of fibrinogen and other macromolecules by integrin alphaXbeta2. Proceedings of the National Academy of Sciences of the United States of America. 102: 1614-9. PMID 15665082 DOI: 10.1073/pnas.0409057102 |
0.412 |
|
| 2005 |
Jiménez D, Roda-Navarro P, Springer TA, Casasnovas JM. Contribution of N-linked glycans to the conformation and function of intercellular adhesion molecules (ICAMs). The Journal of Biological Chemistry. 280: 5854-61. PMID 15545280 DOI: 10.1074/jbc.M412104200 |
0.432 |
|
| 2004 |
Kim M, Carman CV, Yang W, Salas A, Springer TA. The primacy of affinity over clustering in regulation of adhesiveness of the integrin {alpha}L{beta}2. The Journal of Cell Biology. 167: 1241-53. PMID 15611342 DOI: 10.1083/jcb.200404160 |
0.434 |
|
| 2004 |
Jin M, Andricioaei I, Springer TA. Conversion between three conformational states of integrin I domains with a C-terminal pull spring studied with molecular dynamics. Structure (London, England : 1993). 12: 2137-47. PMID 15576028 DOI: 10.1016/J.Str.2004.10.005 |
0.369 |
|
| 2004 |
Shimaoka M, Springer TA. Therapeutic antagonists and the conformational regulation of the beta2 integrins. Current Topics in Medicinal Chemistry. 4: 1485-95. PMID 15544539 DOI: 10.2174/1568026043387575 |
0.408 |
|
| 2004 |
Carman CV, Springer TA. A transmigratory cup in leukocyte diapedesis both through individual vascular endothelial cells and between them. The Journal of Cell Biology. 167: 377-88. PMID 15504916 DOI: 10.1083/jcb.200404129 |
0.335 |
|
| 2004 |
Springer TA, Wang JH. The three-dimensional structure of integrins and their ligands, and conformational regulation of cell adhesion. Advances in Protein Chemistry. 68: 29-63. PMID 15500858 DOI: 10.1016/S0065-3233(04)68002-8 |
0.514 |
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| 2004 |
Xie C, Shimaoka M, Xiao T, Schwab P, Klickstein LB, Springer TA. The integrin alpha-subunit leg extends at a Ca2+-dependent epitope in the thigh/genu interface upon activation. Proceedings of the National Academy of Sciences of the United States of America. 101: 15422-7. PMID 15494438 DOI: 10.1073/pnas.0406680101 |
0.7 |
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| 2004 |
Lafuente EM, van Puijenbroek AA, Krause M, Carman CV, Freeman GJ, Berezovskaya A, Constantine E, Springer TA, Gertler FB, Boussiotis VA. RIAM, an Ena/VASP and Profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion. Developmental Cell. 7: 585-95. PMID 15469846 DOI: 10.1016/J.Devcel.2004.07.021 |
0.388 |
|
| 2004 |
Chen J, Takagi J, Xie C, Xiao T, Luo BH, Springer TA. The relative influence of metal ion binding sites in the I-like domain and the interface with the hybrid domain on rolling and firm adhesion by integrin alpha4beta7. The Journal of Biological Chemistry. 279: 55556-61. PMID 15448154 DOI: 10.1074/jbc.M407773200 |
0.7 |
|
| 2004 |
Xiao T, Takagi J, Coller BS, Wang JH, Springer TA. Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics. Nature. 432: 59-67. PMID 15378069 DOI: 10.1038/Nature02976 |
0.729 |
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| 2004 |
Lu C, Shimaoka M, Salas A, Springer TA. The binding sites for competitive antagonistic, allosteric antagonistic, and agonistic antibodies to the I domain of integrin LFA-1. Journal of Immunology (Baltimore, Md. : 1950). 173: 3972-8. PMID 15356146 DOI: 10.4049/Jimmunol.173.6.3972 |
0.434 |
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| 2004 |
Artoni A, Li J, Mitchell B, Ruan J, Takagi J, Springer TA, French DL, Coller BS. Integrin beta3 regions controlling binding of murine mAb 7E3: implications for the mechanism of integrin alphaIIbbeta3 activation. Proceedings of the National Academy of Sciences of the United States of America. 101: 13114-20. PMID 15277669 DOI: 10.1073/pnas.0404201101 |
0.388 |
|
| 2004 |
Luo BH, Springer TA, Takagi J. A specific interface between integrin transmembrane helices and affinity for ligand. Plos Biology. 2: e153. PMID 15208712 DOI: 10.1371/Journal.Pbio.0020153 |
0.415 |
|
| 2004 |
Luo BH, Strokovich K, Walz T, Springer TA, Takagi J. Allosteric beta1 integrin antibodies that stabilize the low affinity state by preventing the swing-out of the hybrid domain. The Journal of Biological Chemistry. 279: 27466-71. PMID 15123676 DOI: 10.1074/Jbc.M404354200 |
0.43 |
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| 2004 |
Yang Y, Jun CD, Liu JH, Zhang R, Joachimiak A, Springer TA, Wang JH. Structural basis for dimerization of ICAM-1 on the cell surface. Molecular Cell. 14: 269-76. PMID 15099525 DOI: 10.1016/S1097-2765(04)00204-7 |
0.455 |
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| 2004 |
Salas A, Shimaoka M, Kogan AN, Harwood C, von Andrian UH, Springer TA. Rolling adhesion through an extended conformation of integrin alphaLbeta2 and relation to alpha I and beta I-like domain interaction. Immunity. 20: 393-406. PMID 15084269 DOI: 10.1016/S1074-7613(04)00082-2 |
0.406 |
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| 2004 |
Culi J, Springer TA, Mann RS. Boca-dependent maturation of beta-propeller/EGF modules in low-density lipoprotein receptor proteins. The Embo Journal. 23: 1372-80. PMID 15014448 DOI: 10.1038/Sj.Emboj.7600132 |
0.365 |
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| 2004 |
Yang W, Shimaoka M, Chen J, Springer TA. Activation of integrin beta-subunit I-like domains by one-turn C-terminal alpha-helix deletions. Proceedings of the National Academy of Sciences of the United States of America. 101: 2333-8. PMID 14983010 DOI: 10.1073/Pnas.0307291101 |
0.395 |
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| 2004 |
Yang W, Shimaoka M, Salas A, Takagi J, Springer TA. Intersubunit signal transmission in integrins by a receptor-like interaction with a pull spring. Proceedings of the National Academy of Sciences of the United States of America. 101: 2906-11. PMID 14978279 DOI: 10.1073/Pnas.0307340101 |
0.432 |
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| 2004 |
Luo BH, Takagi J, Springer TA. Locking the beta3 integrin I-like domain into high and low affinity conformations with disulfides. The Journal of Biological Chemistry. 279: 10215-21. PMID 14681220 DOI: 10.1074/Jbc.M312732200 |
0.427 |
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| 2004 |
Shimaoka M, Salas A, Yang W, Weitz-Schmidt G, Springer TA. A Small-Molecule Antagonist to Integrin LFA-1 Reveals a Crucial Inter-Domain Communication as a Novel Therapeutic Target. Blood. 104: 650-650. DOI: 10.1182/Blood.V104.11.650.650 |
0.433 |
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| 2004 |
Lafuente EM, Carman CV, Krause M, Springer TA, Gertler FB, Boussiotis VA. RIAM, a New Rap1 Effector, Functions Downstream of Rap1 and Regulates Rap1 Localization at the Plasma Membrane and Rap1-Induced Adhesion. Blood. 104: 510-510. DOI: 10.1182/Blood.V104.11.510.510 |
0.417 |
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| 2004 |
Springer TA, Takagi J, Coller BS, Wang J, Xiao T. Crystal Structure of the Integrin αIIBβ3 Headpiece at 2.7–3.1 Å: Structure, Mechanisms of Activation and Ligand Binding, Inhibition by Eptifibatide, Tirofiban, and mAb 10E5, and Structure of the HPA-1 Alloantigen Epitope. Blood. 104: 327-327. DOI: 10.1182/Blood.V104.11.327.327 |
0.465 |
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| 2003 |
Carman CV, Jun CD, Salas A, Springer TA. Endothelial cells proactively form microvilli-like membrane projections upon intercellular adhesion molecule 1 engagement of leukocyte LFA-1. Journal of Immunology (Baltimore, Md. : 1950). 171: 6135-44. PMID 14634129 DOI: 10.4049/Jimmunol.171.11.6135 |
0.383 |
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| 2003 |
Chen J, Salas A, Springer TA. Bistable regulation of integrin adhesiveness by a bipolar metal ion cluster. Nature Structural Biology. 10: 995-1001. PMID 14608374 DOI: 10.1038/nsb1011 |
0.348 |
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| 2003 |
Carman CV, Springer TA. Integrin avidity regulation: are changes in affinity and conformation underemphasized? Current Opinion in Cell Biology. 15: 547-56. PMID 14519389 DOI: 10.1016/j.ceb.2003.08.003 |
0.325 |
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| 2003 |
Kim M, Carman CV, Springer TA. Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins. Science (New York, N.Y.). 301: 1720-5. PMID 14500982 DOI: 10.1126/science.1084174 |
0.397 |
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| 2003 |
Shimaoka M, Salas A, Yang W, Weitz-Schmidt G, Springer TA. Small molecule integrin antagonists that bind to the beta2 subunit I-like domain and activate signals in one direction and block them in the other. Immunity. 19: 391-402. PMID 14499114 DOI: 10.1016/S1074-7613(03)00238-3 |
0.429 |
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| 2003 |
Takagi J, Strokovich K, Springer TA, Walz T. Structure of integrin alpha5beta1 in complex with fibronectin. The Embo Journal. 22: 4607-15. PMID 12970173 DOI: 10.1093/Emboj/Cdg445 |
0.432 |
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| 2003 |
Shimaoka M, Springer TA. Therapeutic antagonists and conformational regulation of integrin function. Nature Reviews. Drug Discovery. 2: 703-16. PMID 12951577 DOI: 10.1038/nrd1174 |
0.382 |
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| 2003 |
Takagi J, Yang Y, Liu JH, Wang JH, Springer TA. Complex between nidogen and laminin fragments reveals a paradigmatic beta-propeller interface. Nature. 424: 969-74. PMID 12931195 DOI: 10.1038/Nature01873 |
0.491 |
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| 2003 |
Tohyama Y, Katagiri K, Pardi R, Lu C, Springer TA, Kinashi T. The critical cytoplasmic regions of the alphaL/beta2 integrin in Rap1-induced adhesion and migration. Molecular Biology of the Cell. 14: 2570-82. PMID 12808052 DOI: 10.1091/mbc.E02-09-0615 |
0.398 |
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| 2003 |
Luo BH, Springer TA, Takagi J. Stabilizing the open conformation of the integrin headpiece with a glycan wedge increases affinity for ligand. Proceedings of the National Academy of Sciences of the United States of America. 100: 2403-8. PMID 12604783 DOI: 10.1073/Pnas.0438060100 |
0.435 |
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| 2003 |
Luo BH, Springer TA, Takagi J. High affinity ligand binding by integrins does not involve head separation. The Journal of Biological Chemistry. 278: 17185-9. PMID 12600996 DOI: 10.1074/Jbc.M301516200 |
0.429 |
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| 2003 |
Vorup-Jensen T, Ostermeier C, Shimaoka M, Hommel U, Springer TA. Structure and allosteric regulation of the alpha X beta 2 integrin I domain. Proceedings of the National Academy of Sciences of the United States of America. 100: 1873-8. PMID 12554829 DOI: 10.1073/pnas.0237387100 |
0.397 |
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| 2003 |
Shimaoka M, Xiao T, Liu JH, Yang Y, Dong Y, Jun CD, McCormack A, Zhang R, Joachimiak A, Takagi J, Wang JH, Springer TA. Structures of the alpha L I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation. Cell. 112: 99-111. PMID 12526797 DOI: 10.1016/S0092-8674(02)01257-6 |
0.731 |
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| 2002 |
Springer TA. Predicted and experimental structures of integrins and beta-propellers. Current Opinion in Structural Biology. 12: 802-13. PMID 12504686 DOI: 10.1016/S0959-440X(02)00384-6 |
0.375 |
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| 2002 |
Shimaoka M, Lu C, Salas A, Xiao T, Takagi J, Springer TA. Stabilizing the integrin alpha M inserted domain in alternative conformations with a range of engineered disulfide bonds. Proceedings of the National Academy of Sciences of the United States of America. 99: 16737-41. PMID 12466503 DOI: 10.1073/pnas.252633099 |
0.693 |
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| 2002 |
Jing H, Takagi J, Liu JH, Lindgren S, Zhang RG, Joachimiak A, Wang JH, Springer TA. Archaeal surface layer proteins contain beta propeller, PKD, and beta helix domains and are related to metazoan cell surface proteins. Structure (London, England : 1993). 10: 1453-64. PMID 12377130 DOI: 10.1016/S0969-2126(02)00840-7 |
0.462 |
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| 2002 |
Salas A, Shimaoka M, Chen S, Carman CV, Springer T. Transition from rolling to firm adhesion is regulated by the conformation of the I domain of the integrin lymphocyte function-associated antigen-1. The Journal of Biological Chemistry. 277: 50255-62. PMID 12368274 DOI: 10.1074/jbc.M209822200 |
0.421 |
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| 2002 |
Takagi J, Springer TA. Integrin activation and structural rearrangement. Immunological Reviews. 186: 141-63. PMID 12234369 DOI: 10.1034/j.1600-065X.2002.18613.x |
0.467 |
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| 2002 |
Takagi J, Petre BM, Walz T, Springer TA. Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling. Cell. 110: 599-11. PMID 12230977 DOI: 10.1016/S0092-8674(02)00935-2 |
0.422 |
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| 2002 |
Hirose J, Kawashima H, Swope Willis M, Springer TA, Hasegawa H, Yoshie O, Miyasaka M. Chondroitin sulfate B exerts its inhibitory effect on secondary lymphoid tissue chemokine (SLC) by binding to the C-terminus of SLC. Biochimica Et Biophysica Acta. 1571: 219-24. PMID 12090936 DOI: 10.1016/S0304-4165(02)00232-5 |
0.337 |
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| 2002 |
Shimaoka M, Takagi J, Springer TA. Conformational regulation of integrin structure and function. Annual Review of Biophysics and Biomolecular Structure. 31: 485-516. PMID 11988479 DOI: 10.1146/annurev.biophys.31.101101.140922 |
0.446 |
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| 2002 |
Takagi J, DeBottis DP, Erickson HP, Springer TA. The role of the specificity-determining loop of the integrin beta subunit I-like domain in autonomous expression, association with the alpha subunit, and ligand binding. Biochemistry. 41: 4339-47. PMID 11914080 DOI: 10.1021/bi016047u |
0.398 |
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| 2002 |
Beglova N, Blacklow SC, Takagi J, Springer TA. Cysteine-rich module structure reveals a fulcrum for integrin rearrangement upon activation. Nature Structural Biology. 9: 282-7. PMID 11896403 DOI: 10.1038/Nsb779 |
0.403 |
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| 2002 |
Ueno T, Hara K, Willis MS, Malin MA, Höpken UE, Gray DH, Matsushima K, Lipp M, Springer TA, Boyd RL, Yoshie O, Takahama Y. Role for CCR7 ligands in the emigration of newly generated T lymphocytes from the neonatal thymus. Immunity. 16: 205-18. PMID 11869682 DOI: 10.1016/S1074-7613(02)00267-4 |
0.308 |
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| 2002 |
Ma Q, Shimaoka M, Lu C, Jing H, Carman CV, Springer TA. Activation-induced conformational changes in the I domain region of lymphocyte function-associated antigen 1. The Journal of Biological Chemistry. 277: 10638-41. PMID 11792712 DOI: 10.1074/jbc.M112417200 |
0.445 |
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| 2001 |
Bonifacino JS, Dell'Angelica EC, Springer TA. Immunoprecipitation. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit 8.3. PMID 18432858 DOI: 10.1002/0471142735.Im0803S41 |
0.323 |
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| 2001 |
Springer TA. Immunoaffinity chromatography. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit 8.2. PMID 18432857 DOI: 10.1002/0471142735.im0802s18 |
0.309 |
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| 2001 |
Bonifacino JS, Dell'Angelica EC, Springer TA. Immunoprecipitation. Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.]. Unit 9.8. PMID 18429217 DOI: 10.1002/0471140864.Ps0908S18 |
0.307 |
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| 2001 |
Springer TA. Immunoaffinity chromatography. Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.]. Unit 9.5. PMID 18429214 DOI: 10.1002/0471140864.ps0905s03 |
0.338 |
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| 2001 |
Takagi J, Beglova N, Yalamanchili P, Blacklow SC, Springer TA. Definition of EGF-like, closely interacting modules that bear activation epitopes in integrin beta subunits. Proceedings of the National Academy of Sciences of the United States of America. 98: 11175-80. PMID 11572973 DOI: 10.1073/Pnas.201420198 |
0.413 |
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| 2001 |
Manjunath N, Shankar P, Wan J, Weninger W, Crowley MA, Hieshima K, Springer TA, Fan X, Shen H, Lieberman J, von Andrian UH. Effector differentiation is not prerequisite for generation of memory cytotoxic T lymphocytes. The Journal of Clinical Investigation. 108: 871-8. PMID 11560956 DOI: 10.1172/Jci13296 |
0.312 |
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| 2001 |
Kamata T, Tieu KK, Irie A, Springer TA, Takada Y. Amino acid residues in the alpha IIb subunit that are critical for ligand binding to integrin alpha IIbbeta 3 are clustered in the beta-propeller model. The Journal of Biological Chemistry. 276: 44275-83. PMID 11557768 DOI: 10.1074/jbc.M107021200 |
0.403 |
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| 2001 |
Jun CD, Shimaoka M, Carman CV, Takagi J, Springer TA. Dimerization and the effectiveness of ICAM-1 in mediating LFA-1-dependent adhesion. Proceedings of the National Academy of Sciences of the United States of America. 98: 6830-5. PMID 11391003 DOI: 10.1073/pnas.121186998 |
0.372 |
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| 2001 |
Jun CD, Carman CV, Redick SD, Shimaoka M, Erickson HP, Springer TA. Ultrastructure and function of dimeric, soluble intercellular adhesion molecule-1 (ICAM-1). The Journal of Biological Chemistry. 276: 29019-27. PMID 11390397 DOI: 10.1074/jbc.M103394200 |
0.405 |
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| 2001 |
Jeon H, Meng W, Takagi J, Eck MJ, Springer TA, Blacklow SC. Implications for familial hypercholesterolemia from the structure of the LDL receptor YWTD-EGF domain pair. Nature Structural Biology. 8: 499-504. PMID 11373616 DOI: 10.1038/88556 |
0.341 |
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| 2001 |
Shimaoka M, Lu C, Palframan RT, von Andrian UH, McCormack A, Takagi J, Springer TA. Reversibly locking a protein fold in an active conformation with a disulfide bond: integrin alphaL I domains with high affinity and antagonist activity in vivo. Proceedings of the National Academy of Sciences of the United States of America. 98: 6009-14. PMID 11353828 DOI: 10.1073/pnas.101130498 |
0.425 |
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| 2001 |
Takagi J, Erickson HP, Springer TA. C-terminal opening mimics 'inside-out' activation of integrin alpha5beta1. Nature Structural Biology. 8: 412-6. PMID 11323715 DOI: 10.1038/87569 |
0.439 |
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| 2001 |
Lu C, Ferzly M, Takagi J, Springer TA. Epitope mapping of antibodies to the C-terminal region of the integrin beta 2 subunit reveals regions that become exposed upon receptor activation. Journal of Immunology (Baltimore, Md. : 1950). 166: 5629-37. PMID 11313403 DOI: 10.4049/Jimmunol.166.9.5629 |
0.372 |
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| 2001 |
Lu C, Takagi J, Springer TA. Association of the membrane proximal regions of the alpha and beta subunit cytoplasmic domains constrains an integrin in the inactive state. The Journal of Biological Chemistry. 276: 14642-8. PMID 11279101 DOI: 10.1074/jbc.M100600200 |
0.384 |
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| 2001 |
Lu C, Shimaoka M, Zang Q, Takagi J, Springer TA. Locking in alternate conformations of the integrin alphaLbeta2 I domain with disulfide bonds reveals functional relationships among integrin domains. Proceedings of the National Academy of Sciences of the United States of America. 98: 2393-8. PMID 11226250 DOI: 10.1073/pnas.041618598 |
0.411 |
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| 2001 |
Lu C, Shimaoka M, Ferzly M, Oxvig C, Takagi J, Springer TA. An isolated, surface-expressed I domain of the integrin alphaLbeta2 is sufficient for strong adhesive function when locked in the open conformation with a disulfide bond. Proceedings of the National Academy of Sciences of the United States of America. 98: 2387-92. PMID 11226249 DOI: 10.1073/pnas.041606398 |
0.422 |
|
| 2001 |
Zang Q, Springer TA. Amino acid residues in the PSI domain and cysteine-rich repeats of the integrin beta2 subunit that restrain activation of the integrin alpha(X)beta(2). The Journal of Biological Chemistry. 276: 6922-9. PMID 11096074 DOI: 10.1074/jbc.M005868200 |
0.399 |
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| 2000 |
Springer TA, Jing H, Takagi J. A novel Ca2+ binding beta hairpin loop better resembles integrin sequence motifs than the EF hand. Cell. 102: 275-7. PMID 10975518 DOI: 10.1016/S0092-8674(00)00033-7 |
0.319 |
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| 2000 |
Shimaoka M, Shifman JM, Jing H, Takagi J, Mayo SL, Springer TA. Computational design of an integrin I domain stabilized in the open high affinity conformation. Nature Structural Biology. 7: 674-8. PMID 10932253 DOI: 10.1038/77978 |
0.379 |
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| 2000 |
Zang Q, Lu C, Huang C, Takagi J, Springer TA. The top of the inserted-like domain of the integrin lymphocyte function-associated antigen-1 beta subunit contacts the alpha subunit beta -propeller domain near beta-sheet 3. The Journal of Biological Chemistry. 275: 22202-12. PMID 10781608 DOI: 10.1074/jbc.M002883200 |
0.388 |
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| 2000 |
Huang C, Zang Q, Takagi J, Springer TA. Structural and functional studies with antibodies to the integrin beta 2 subunit. A model for the I-like domain. The Journal of Biological Chemistry. 275: 21514-24. PMID 10779511 DOI: 10.1074/jbc.M002286200 |
0.402 |
|
| 2000 |
Yalamanchili P, Lu C, Oxvig C, Springer TA. Folding and function of I domain-deleted Mac-1 and lymphocyte function-associated antigen-1. The Journal of Biological Chemistry. 275: 21877-82. PMID 10764808 DOI: 10.1074/jbc.M908868199 |
0.445 |
|
| 1999 |
Green N, Rosebrook J, Cochran N, Tan K, Wang JH, Springer TA, Briskin MJ. Mutational analysis of MAdCAM-1/alpha4beta7 interactions reveals significant binding determinants in both the first and second immunuglobulin domains. Cell Adhesion and Communication. 7: 167-81. PMID 10626902 DOI: 10.3109/15419069909010800 |
0.529 |
|
| 1999 |
Fedyk ER, Ryyan DH, Ritterman I, Springer TA. Maturation decreases responsiveness of human bone marrow B lineage cells to stromal-derived factor 1 (SDF-1). Journal of Leukocyte Biology. 66: 667-73. PMID 10534124 DOI: 10.1002/Jlb.66.4.667 |
0.305 |
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| 1999 |
Casasnovas JM, Pieroni C, Springer TA. Lymphocyte function-associated antigen-1 binding residues in intercellular adhesion molecule-2 (ICAM-2) and the integrin binding surface in the ICAM subfamily. Proceedings of the National Academy of Sciences of the United States of America. 96: 3017-22. PMID 10077629 DOI: 10.1073/Pnas.96.6.3017 |
0.46 |
|
| 1999 |
Oxvig C, Lu C, Springer TA. Conformational changes in tertiary structure near the ligand binding site of an integrin I domain. Proceedings of the National Academy of Sciences of the United States of America. 96: 2215-20. PMID 10051621 DOI: 10.1073/Pnas.96.5.2215 |
0.4 |
|
| 1999 |
Issekutz AC, Rowter D, Springer TA. Role of ICAM-1 and ICAM-2 and alternate CD11/CD18 ligands in neutrophil transendothelial migration. Journal of Leukocyte Biology. 65: 117-26. PMID 9886254 DOI: 10.1002/Jlb.65.1.117 |
0.332 |
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| 1998 |
Springer TA. An extracellular beta-propeller module predicted in lipoprotein and scavenger receptors, tyrosine kinases, epidermal growth factor precursor, and extracellular matrix components. Journal of Molecular Biology. 283: 837-62. PMID 9790844 DOI: 10.1006/jmbi.1998.2115 |
0.365 |
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| 1998 |
Alon R, Chen S, Fuhlbrigge R, Puri KD, Springer TA. The kinetics and shear threshold of transient and rolling interactions of L-selectin with its ligand on leukocytes. Proceedings of the National Academy of Sciences of the United States of America. 95: 11631-6. PMID 9751717 DOI: 10.1073/Pnas.95.20.11631 |
0.331 |
|
| 1998 |
Wang J, Springer TA. Structural specializations of immunoglobulin superfamily members for adhesion to integrins and viruses. Immunological Reviews. 163: 197-215. PMID 9700512 DOI: 10.1111/J.1600-065X.1998.Tb01198.X |
0.553 |
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| 1998 |
Ma Q, Jones D, Borghesani PR, Segal RA, Nagasawa T, Kishimoto T, Bronson RT, Springer TA. Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 95: 9448-53. PMID 9689100 DOI: 10.1073/Pnas.95.16.9448 |
0.319 |
|
| 1998 |
Tan K, Casasnovas JM, Liu JH, Briskin MJ, Springer TA, Wang JH. The structure of immunoglobulin superfamily domains 1 and 2 of MAdCAM-1 reveals novel features important for integrin recognition. Structure (London, England : 1993). 6: 793-801. PMID 9655832 DOI: 10.1016/S0969-2126(98)00080-X |
0.532 |
|
| 1998 |
Casasnovas JM, Bickford JK, Springer TA. The domain structure of ICAM-1 and the kinetics of binding to rhinovirus. Journal of Virology. 72: 6244-6. PMID 9621098 DOI: 10.1128/Jvi.72.7.6244-6246.1998 |
0.4 |
|
| 1998 |
Lu C, Oxvig C, Springer TA. The structure of the beta-propeller domain and C-terminal region of the integrin alphaM subunit. Dependence on beta subunit association and prediction of domains. The Journal of Biological Chemistry. 273: 15138-47. PMID 9614126 DOI: 10.1074/jbc.273.24.15138 |
0.358 |
|
| 1998 |
Puri KD, Chen S, Springer TA. Modifying the mechanical property and shear threshold of L-selectin adhesion independently of equilibrium properties. Nature. 392: 930-3. PMID 9582074 DOI: 10.1038/31954 |
0.346 |
|
| 1998 |
Kitayama J, Mackay CR, Ponath PD, Springer TA. The C-C chemokine receptor CCR3 participates in stimulation of eosinophil arrest on inflammatory endothelium in shear flow. The Journal of Clinical Investigation. 101: 2017-24. PMID 9576767 DOI: 10.1172/JCI2688 |
0.396 |
|
| 1998 |
Petruzzelli L, Maduzia L, Springer TA. Differential requirements for LFA-1 binding to ICAM-1 and LFA-1-mediated cell aggregation. Journal of Immunology (Baltimore, Md. : 1950). 160: 4208-16. PMID 9574521 |
0.319 |
|
| 1998 |
Oxvig C, Springer TA. Experimental support for a beta-propeller domain in integrin alpha-subunits and a calcium binding site on its lower surface. Proceedings of the National Academy of Sciences of the United States of America. 95: 4870-5. PMID 9560195 DOI: 10.1073/Pnas.95.9.4870 |
0.43 |
|
| 1998 |
Piali L, Weber C, LaRosa G, Mackay CR, Springer TA, Clark-Lewis I, Moser B. The chemokine receptor CXCR3 mediates rapid and shear-resistant adhesion-induction of effector T lymphocytes by the chemokines IP10 and Mig. European Journal of Immunology. 28: 961-72. PMID 9541591 DOI: 10.1002/(SICI)1521-4141(199803)28:03<961::AID-IMMU961>3.0.CO;2-4 |
0.354 |
|
| 1998 |
Casasnovas JM, Stehle T, Liu JH, Wang JH, Springer TA. A dimeric crystal structure for the N-terminal two domains of intercellular adhesion molecule-1. Proceedings of the National Academy of Sciences of the United States of America. 95: 4134-9. PMID 9539702 DOI: 10.1073/Pnas.95.8.4134 |
0.496 |
|
| 1998 |
Roth SJ, Diacovo TG, Brenner MB, Rosat JP, Buccola J, Morita CT, Springer TA. Transendothelial chemotaxis of human alpha/beta and gamma/delta T lymphocytes to chemokines. European Journal of Immunology. 28: 104-13. PMID 9485190 DOI: 10.1002/(Sici)1521-4141(199801)28:01<104::Aid-Immu104>3.0.Co;2-F |
0.541 |
|
| 1998 |
Bleul CC, Schultze JL, Springer TA. B lymphocyte chemotaxis regulated in association with microanatomic localization, differentiation state, and B cell receptor engagement. The Journal of Experimental Medicine. 187: 753-62. PMID 9480985 DOI: 10.1084/Jem.187.5.753 |
0.324 |
|
| 1998 |
Clark RA, Fuhlbrigge RC, Springer TA. L-Selectin ligands that are O-glycoprotease resistant and distinct from MECA-79 antigen are sufficient for tethering and rolling of lymphocytes on human high endothelial venules. The Journal of Cell Biology. 140: 721-31. PMID 9456330 DOI: 10.1083/Jcb.140.3.721 |
0.383 |
|
| 1997 |
Pujades C, Alon R, Yauch RL, Masumoto A, Burkly LC, Chen C, Springer TA, Lobb RR, Hemler ME. Defining extracellular integrin alpha-chain sites that affect cell adhesion and adhesion strengthening without altering soluble ligand binding. Molecular Biology of the Cell. 8: 2647-57. PMID 9398682 DOI: 10.1091/Mbc.8.12.2647 |
0.42 |
|
| 1997 |
Weber C, Springer TA. Neutrophil accumulation on activated, surface-adherent platelets in flow is mediated by interaction of Mac-1 with fibrinogen bound to alphaIIbbeta3 and stimulated by platelet-activating factor. The Journal of Clinical Investigation. 100: 2085-93. PMID 9329974 DOI: 10.1172/JCI119742 |
0.319 |
|
| 1997 |
Lu CF, Springer TA. The alpha subunit cytoplasmic domain regulates the assembly and adhesiveness of integrin lymphocyte function-associated antigen-1. Journal of Immunology (Baltimore, Md. : 1950). 159: 268-78. PMID 9200463 |
0.324 |
|
| 1997 |
Casasnovas JM, Springer TA, Liu JH, Harrison SC, Wang JH. Crystal structure of ICAM-2 reveals a distinctive integrin recognition surface. Nature. 387: 312-5. PMID 9153399 DOI: 10.1038/387312A0 |
0.524 |
|
| 1997 |
Clark RA, Erickson HP, Springer TA. Tenascin supports lymphocyte rolling. The Journal of Cell Biology. 137: 755-65. PMID 9151679 DOI: 10.1083/jcb.137.3.755 |
0.441 |
|
| 1997 |
Chen S, Alon R, Fuhlbrigge RC, Springer TA. Rolling and transient tethering of leukocytes on antibodies reveal specializations of selectins. Proceedings of the National Academy of Sciences of the United States of America. 94: 3172-7. PMID 9096365 DOI: 10.1073/Pnas.94.7.3172 |
0.343 |
|
| 1997 |
Huang C, Springer TA. Folding of the beta-propeller domain of the integrin alphaL subunit is independent of the I domain and dependent on the beta2 subunit. Proceedings of the National Academy of Sciences of the United States of America. 94: 3162-7. PMID 9096363 DOI: 10.1073/PNAS.94.7.3162 |
0.346 |
|
| 1997 |
Huang C, Lu C, Springer TA. Folding of the conserved domain but not of flanking regions in the integrin beta2 subunit requires association with the alpha subunit. Proceedings of the National Academy of Sciences of the United States of America. 94: 3156-61. PMID 9096362 DOI: 10.1073/PNAS.94.7.3156 |
0.36 |
|
| 1997 |
Bleul CC, Wu L, Hoxie JA, Springer TA, Mackay CR. The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 94: 1925-30. PMID 9050881 DOI: 10.1073/Pnas.94.5.1925 |
0.343 |
|
| 1997 |
Springer TA. Folding of the N-terminal, ligand-binding region of integrin alpha-subunits into a beta-propeller domain. Proceedings of the National Academy of Sciences of the United States of America. 94: 65-72. PMID 8990162 DOI: 10.1073/PNAS.94.1.65 |
0.348 |
|
| 1996 |
Bleul CC, Fuhlbrigge RC, Casasnovas JM, Aiuti A, Springer TA. A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1) The Journal of Experimental Medicine. 184: 1101-9. PMID 9064327 DOI: 10.1084/Jem.184.3.1101 |
0.351 |
|
| 1996 |
Nagasawa T, Nakajima T, Tachibana K, Iizasa H, Bleul CC, Yoshie O, Matsushima K, Yoshida N, Springer TA, Kishimoto T. Molecular cloning and characterization of a murine pre-B-cell growth-stimulating factor/stromal cell-derived factor 1 receptor, a murine homolog of the human immunodeficiency virus 1 entry coreceptor fusin. Proceedings of the National Academy of Sciences of the United States of America. 93: 14726-9. PMID 8962122 DOI: 10.1073/Pnas.93.25.14726 |
0.316 |
|
| 1996 |
Alon R, Fuhlbrigge RC, Finger EB, Springer TA. Interactions through L-selectin between leukocytes and adherent leukocytes nucleate rolling adhesions on selectins and VCAM-1 in shear flow. The Journal of Cell Biology. 135: 849-65. PMID 8909556 DOI: 10.1083/Jcb.135.3.849 |
0.37 |
|
| 1996 |
Fuhlbrigge RC, Alon R, Puri KD, Lowe JB, Springer TA. Sialylated, fucosylated ligands for L-selectin expressed on leukocytes mediate tethering and rolling adhesions in physiologic flow conditions. The Journal of Cell Biology. 135: 837-48. PMID 8909555 DOI: 10.1083/Jcb.135.3.837 |
0.345 |
|
| 1996 |
Weber C, Kitayama J, Springer TA. Differential regulation of beta 1 and beta 2 integrin avidity by chemoattractants in eosinophils. Proceedings of the National Academy of Sciences of the United States of America. 93: 10939-44. PMID 8855287 DOI: 10.1073/Pnas.93.20.10939 |
0.396 |
|
| 1996 |
Parkos CA, Colgan SP, Diamond MS, Nusrat A, Liang TW, Springer TA, Madara JL. Expression and polarization of intercellular adhesion molecule-1 on human intestinal epithelia: consequences for CD11b/CD18-mediated interactions with neutrophils. Molecular Medicine (Cambridge, Mass.). 2: 489-505. PMID 8827719 DOI: 10.1007/Bf03401908 |
0.479 |
|
| 1996 |
Klickstein LB, York MR, Fougerolles AR, Springer TA. Localization of the binding site on intercellular adhesion molecule-3 (ICAM-3) for lymphocyte function-associated antigen 1 (LFA-1). The Journal of Biological Chemistry. 271: 23920-7. PMID 8798624 DOI: 10.1074/Jbc.271.39.23920 |
0.46 |
|
| 1996 |
Clark RA, Alon R, Springer TA. CD44 and hyaluronan-dependent rolling interactions of lymphocytes on tonsillar stroma. The Journal of Cell Biology. 134: 1075-87. PMID 8769428 DOI: 10.1083/Jcb.134.4.1075 |
0.366 |
|
| 1996 |
Weber C, Alon R, Moser B, Springer TA. Sequential regulation of alpha 4 beta 1 and alpha 5 beta 1 integrin avidity by CC chemokines in monocytes: implications for transendothelial chemotaxis. The Journal of Cell Biology. 134: 1063-73. PMID 8769427 DOI: 10.1083/Jcb.134.4.1063 |
0.408 |
|
| 1996 |
Bruehl RE, Springer TA, Bainton DF. Quantitation of L-selectin distribution on human leukocyte microvilli by immunogold labeling and electron microscopy. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 44: 835-44. PMID 8756756 DOI: 10.1177/44.8.8756756 |
0.317 |
|
| 1996 |
Diacovo TG, Roth SJ, Buccola JM, Bainton DF, Springer TA. Neutrophil rolling, arrest, and transmigration across activated, surface-adherent platelets via sequential action of P-selectin and the beta 2-integrin CD11b/CD18. Blood. 88: 146-57. PMID 8704169 DOI: 10.1182/Blood.V88.1.146.Bloodjournal881146 |
0.38 |
|
| 1996 |
Wong DA, Davis EM, LeBeau M, Springer TA. Cloning and chromosomal localization of a novel gene-encoding a human beta 2-integrin alpha subunit. Gene. 171: 291-4. PMID 8666289 DOI: 10.1016/0378-1119(95)00869-1 |
0.301 |
|
| 1996 |
Diacovo TG, Puri KD, Warnock RA, Springer TA, von Andrian UH. Platelet-mediated lymphocyte delivery to high endothelial venules. Science (New York, N.Y.). 273: 252-5. PMID 8662511 DOI: 10.1126/science.273.5272.252 |
0.335 |
|
| 1996 |
Diacovo TG, Roth SJ, Morita CT, Rosat JP, Brenner MB, Springer TA. Interactions of human alpha/beta and gamma/delta T lymphocyte subsets in shear flow with E-selectin and P-selectin. The Journal of Experimental Medicine. 183: 1193-203. PMID 8642261 DOI: 10.1084/Jem.183.3.1193 |
0.569 |
|
| 1996 |
Dustin ML, Ferguson LM, Chan PY, Springer TA, Golan DE. Visualization of CD2 interaction with LFA-3 and determination of the two-dimensional dissociation constant for adhesion receptors in a contact area. The Journal of Cell Biology. 132: 465-74. PMID 8636222 DOI: 10.1083/Jcb.132.3.465 |
0.546 |
|
| 1996 |
Girard JP, Springer TA. Modulation of endothelial cell adhesion by hevin, an acidic protein associated with high endothelial venules. The Journal of Biological Chemistry. 271: 4511-7. PMID 8626806 DOI: 10.1074/Jbc.271.8.4511 |
0.348 |
|
| 1996 |
Carr MW, Alon R, Springer TA. The C-C chemokine MCP-1 differentially modulates the avidity of beta 1 and beta 2 integrins on T lymphocytes. Immunity. 4: 179-87. PMID 8624808 DOI: 10.1016/S1074-7613(00)80682-2 |
0.391 |
|
| 1996 |
Puri KD, Springer TA. A schiff base with mildly oxidized carbohydrate ligands stabilizes L-selectin and not P-selectin or E-selectin rolling adhesions in shear flow. The Journal of Biological Chemistry. 271: 5404-13. PMID 8621395 DOI: 10.1074/Jbc.271.10.5404 |
0.336 |
|
| 1996 |
Finger EB, Puri KD, Alon R, Lawrence MB, von Andrian UH, Springer TA. Adhesion through L-selectin requires a threshold hydrodynamic shear. Nature. 379: 266-9. PMID 8538793 DOI: 10.1038/379266A0 |
0.37 |
|
| 1996 |
Wang J, Casanovas J, Springer T, Liu JH, Harrison SC. The crystal structure of ICAM-2, its comparison to other integrin-binding proteins Acta Crystallographica Section a Foundations of Crystallography. 52: C216-C216. DOI: 10.1107/S010876739609071X |
0.32 |
|
| 1995 |
de Fougerolles A, Springer TA. Ideas crystallized on immunoglobulin superfamily-integrin interactions. Chemistry & Biology. 2: 639-43. PMID 9383469 DOI: 10.1016/1074-5521(95)90024-1 |
0.353 |
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| 1995 |
Roth SJ, Carr MW, Springer TA. C-C chemokines, but not the C-X-C chemokines interleukin-8 and interferon-gamma inducible protein-10, stimulate transendothelial chemotaxis of T lymphocytes. European Journal of Immunology. 25: 3482-8. PMID 8566041 DOI: 10.1002/eji.1830251241 |
0.317 |
|
| 1995 |
Gonzalo JA, Martinez C, Springer TA, Gutierrez-Ramos JC. ICAM-1 is required for T cell proliferation but not for anergy or apoptosis induced by Staphylococcus aureus enterotoxin B in vivo. International Immunology. 7: 1691-8. PMID 8562515 DOI: 10.1093/Intimm/7.10.1691 |
0.373 |
|
| 1995 |
Roth SJ, Carr MW, Rose SS, Springer TA. Characterization of transendothelial chemotaxis of T lymphocytes. Journal of Immunological Methods. 188: 97-116. PMID 8551044 DOI: 10.1016/0022-1759(95)00208-1 |
0.418 |
|
| 1995 |
Kinashi T, Springer TA. Regulation of cell-matrix adhesion by receptor tyrosine kinases. Leukemia & Lymphoma. 18: 203-8. PMID 8535183 DOI: 10.3109/10428199509059608 |
0.354 |
|
| 1995 |
Casasnovas JM, Springer TA. Kinetics and thermodynamics of virus binding to receptor. Studies with rhinovirus, intercellular adhesion molecule-1 (ICAM-1), and surface plasmon resonance. The Journal of Biological Chemistry. 270: 13216-24. PMID 7768920 DOI: 10.1074/JBC.270.22.13216 |
0.393 |
|
| 1995 |
de Fougerolles AR, Diamond MS, Springer TA. Heterogenous glycosylation of ICAM-3 and lack of interaction with Mac-1 and p150,95. European Journal of Immunology. 25: 1008-12. PMID 7737271 DOI: 10.1002/Eji.1830250422 |
0.543 |
|
| 1995 |
Huang C, Springer TA. A binding interface on the I domain of lymphocyte function-associated antigen-1 (LFA-1) required for specific interaction with intercellular adhesion molecule 1 (ICAM-1). The Journal of Biological Chemistry. 270: 19008-16. PMID 7642561 DOI: 10.1074/Jbc.270.32.19008 |
0.466 |
|
| 1995 |
Petruzzelli L, Maduzia L, Springer TA. Activation of lymphocyte function-associated molecule-1 (CD11a/CD18) and Mac-1 (CD11b/CD18) mimicked by an antibody directed against CD18. Journal of Immunology (Baltimore, Md. : 1950). 155: 854-66. PMID 7608563 |
0.31 |
|
| 1995 |
Girard JP, Springer TA. Cloning from purified high endothelial venule cells of hevin, a close relative of the antiadhesive extracellular matrix protein SPARC. Immunity. 2: 113-23. PMID 7600298 DOI: 10.1016/1074-7613(95)90083-7 |
0.34 |
|
| 1995 |
Kassner PD, Alon R, Springer TA, Hemler ME. Specialized functional properties of the integrin alpha 4 cytoplasmic domain. Molecular Biology of the Cell. 6: 661-74. PMID 7579686 DOI: 10.1091/Mbc.6.6.661 |
0.367 |
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| 1995 |
Puri KD, Finger EB, Gaudernack G, Springer TA. Sialomucin CD34 is the major L-selectin ligand in human tonsil high endothelial venules. The Journal of Cell Biology. 131: 261-70. PMID 7559783 DOI: 10.1083/Jcb.131.1.261 |
0.302 |
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| 1995 |
Diamond MS, Alon R, Parkos CA, Quinn MT, Springer TA. Heparin is an adhesive ligand for the leukocyte integrin Mac-1 (CD11b/CD1). The Journal of Cell Biology. 130: 1473-82. PMID 7559767 DOI: 10.1083/Jcb.130.6.1473 |
0.575 |
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| 1995 |
Sugie K, Nakamura K, Teshigawara K, Diamond MS, Springer TA, Nakamura Y, Leonard WJ, Uchida A, Yodoi J. Activation of natural killer cells by the mAb YTA-1 that recognizes leukocyte function-associated antigen-1. International Immunology. 7: 763-9. PMID 7547703 DOI: 10.1093/intimm/7.5.763 |
0.464 |
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| 1995 |
Lawrence MB, Berg EL, Butcher EC, Springer TA. Rolling of lymphocytes and neutrophils on peripheral node addressin and subsequent arrest on ICAM-1 in shear flow. European Journal of Immunology. 25: 1025-31. PMID 7537667 DOI: 10.1002/eji.1830250425 |
0.354 |
|
| 1995 |
Alon R, Kassner PD, Carr MW, Finger EB, Hemler ME, Springer TA. The integrin VLA-4 supports tethering and rolling in flow on VCAM-1. The Journal of Cell Biology. 128: 1243-53. PMID 7534768 DOI: 10.1083/Jcb.128.6.1243 |
0.383 |
|
| 1995 |
Kinashi T, St Pierre Y, Springer TA. Expression of glycophosphatidylinositol-anchored and -non-anchored isoforms of vascular cell adhesion molecule 1 in murine stromal and endothelial cells. Journal of Leukocyte Biology. 57: 168-73. PMID 7530279 DOI: 10.1002/Jlb.57.1.168 |
0.393 |
|
| 1994 |
Carr MW, Roth SJ, Luther E, Rose SS, Springer TA. Monocyte chemoattractant protein 1 acts as a T-lymphocyte chemoattractant. Proceedings of the National Academy of Sciences of the United States of America. 91: 3652-6. PMID 8170963 DOI: 10.1073/Pnas.91.9.3652 |
0.33 |
|
| 1994 |
Diacovo TG, deFougerolles AR, Bainton DF, Springer TA. A functional integrin ligand on the surface of platelets: intercellular adhesion molecule-2. The Journal of Clinical Investigation. 94: 1243-51. PMID 8083366 DOI: 10.1172/JCI117442 |
0.397 |
|
| 1994 |
Diamond MS, Springer TA. The dynamic regulation of integrin adhesiveness. Current Biology : Cb. 4: 506-17. PMID 7922371 DOI: 10.1016/S0960-9822(00)00111-1 |
0.486 |
|
| 1994 |
Butini L, De Fougerolles AR, Vaccarezza M, Graziosi C, Cohen DI, Montroni M, Springer TA, Pantaleo G, Fauci AS. Intercellular adhesion molecules (ICAM)-1 ICAM-2 and ICAM-3 function as counter-receptors for lymphocyte function-associated molecule 1 in human immunodeficiency virus-mediated syncytia formation. European Journal of Immunology. 24: 2191-5. PMID 7916296 DOI: 10.1002/eji.1830240939 |
0.354 |
|
| 1994 |
Xu H, Gonzalo JA, St Pierre Y, Williams IR, Kupper TS, Cotran RS, Springer TA, Gutierrez-Ramos JC. Leukocytosis and resistance to septic shock in intercellular adhesion molecule 1-deficient mice. The Journal of Experimental Medicine. 180: 95-109. PMID 7911822 DOI: 10.1084/jem.180.1.95 |
0.312 |
|
| 1994 |
Bilsland CA, Springer TA. Cloning and expression of the chicken CD18 cDNA. Journal of Leukocyte Biology. 55: 501-6. PMID 7908319 DOI: 10.1002/Jlb.55.4.501 |
0.405 |
|
| 1994 |
de Fougerolles AR, Qin X, Springer TA. Characterization of the function of intercellular adhesion molecule (ICAM)-3 and comparison with ICAM-1 and ICAM-2 in immune responses. The Journal of Experimental Medicine. 179: 619-29. PMID 7905020 DOI: 10.1084/Jem.179.2.619 |
0.386 |
|
| 1994 |
Lawrence MB, Bainton DF, Springer TA. Neutrophil tethering to and rolling on E-selectin are separable by requirement for L-selectin. Immunity. 1: 137-45. PMID 7534197 DOI: 10.1016/1074-7613(94)90107-4 |
0.327 |
|
| 1994 |
Alon R, Rossiter H, Wang X, Springer TA, Kupper TS. Distinct cell surface ligands mediate T lymphocyte attachment and rolling on P and E selectin under physiological flow. The Journal of Cell Biology. 127: 1485-95. PMID 7525609 DOI: 10.1083/Jcb.127.5.1485 |
0.376 |
|
| 1994 |
Borregaard N, Kjeldsen L, Sengeløv H, Diamond MS, Springer TA, Anderson HC, Kishimoto TK, Bainton DF. Changes in subcellular localization and surface expression of L-selectin, alkaline phosphatase, and Mac-1 in human neutrophils during stimulation with inflammatory mediators. Journal of Leukocyte Biology. 56: 80-7. PMID 7517990 DOI: 10.1002/Jlb.56.1.80 |
0.49 |
|
| 1994 |
Bilsland CA, Diamond MS, Springer TA. The leukocyte integrin p150,95 (CD11c/CD18) as a receptor for iC3b. Activation by a heterologous beta subunit and localization of a ligand recognition site to the I domain. Journal of Immunology (Baltimore, Md. : 1950). 152: 4582-9. PMID 7512600 |
0.495 |
|
| 1994 |
Vonderheide RH, Tedder TF, Springer TA, Staunton DE. Residues within a conserved amino acid motif of domains 1 and 4 of VCAM-1 are required for binding to VLA-4. The Journal of Cell Biology. 125: 215-22. PMID 7511143 DOI: 10.1083/Jcb.125.1.215 |
0.45 |
|
| 1994 |
Kinashi T, Springer TA. Steel factor and c-kit regulate cell-matrix adhesion. Blood. 83: 1033-8. PMID 7509207 DOI: 10.1182/Blood.V83.4.1033.Bloodjournal8341033 |
0.338 |
|
| 1993 |
Hondalus MK, Diamond MS, Rosenthal LA, Springer TA, Mosser DM. The intracellular bacterium Rhodococcus equi requires Mac-1 to bind to mammalian cells. Infection and Immunity. 61: 2919-29. PMID 8514396 DOI: 10.1128/Iai.61.7.2919-2929.1993 |
0.543 |
|
| 1993 |
de Fougerolles AR, Klickstein LB, Springer TA. Cloning and expression of intercellular adhesion molecule 3 reveals strong homology to other immunoglobulin family counter-receptors for lymphocyte function-associated antigen 1. The Journal of Experimental Medicine. 177: 1187-92. PMID 8459213 DOI: 10.1084/JEM.177.4.1187 |
0.397 |
|
| 1993 |
Sengeløv H, Kjeldsen L, Diamond MS, Springer TA, Borregaard N. Subcellular localization and dynamics of Mac-1 (alpha m beta 2) in human neutrophils. The Journal of Clinical Investigation. 92: 1467-76. PMID 8376598 DOI: 10.1172/Jci116724 |
0.473 |
|
| 1993 |
Martin S, Martin A, Staunton DE, Springer TA. Functional studies of truncated soluble intercellular adhesion molecule 1 expressed in Escherichia coli. Antimicrobial Agents and Chemotherapy. 37: 1278-84. PMID 8101071 DOI: 10.1128/AAC.37.6.1278 |
0.419 |
|
| 1993 |
Martin S, Casasnovas JM, Staunton DE, Springer TA. Efficient neutralization and disruption of rhinovirus by chimeric ICAM-1/immunoglobulin molecules. Journal of Virology. 67: 3561-8. PMID 8098781 DOI: 10.1128/JVI.67.6.3561-3568.1993 |
0.365 |
|
| 1993 |
Kirchhausen T, Staunton DE, Springer TA. Location of the domains of ICAM-1 by immunolabeling and single-molecule electron microscopy Journal of Leukocyte Biology. 53: 342-346. PMID 8095966 DOI: 10.1002/Jlb.53.3.342 |
0.356 |
|
| 1993 |
Diamond MS, Garcia-Aguilar J, Bickford JK, Corbi AL, Springer TA. The I domain is a major recognition site on the leukocyte integrin Mac-1 (CD11b/CD18) for four distinct adhesion ligands. The Journal of Cell Biology. 120: 1031-43. PMID 7679388 DOI: 10.1083/Jcb.120.4.1031 |
0.577 |
|
| 1993 |
Diamond MS, Springer TA. A subpopulation of Mac-1 (CD11b/CD18) molecules mediates neutrophil adhesion to ICAM-1 and fibrinogen. The Journal of Cell Biology. 120: 545-56. PMID 7678422 DOI: 10.1083/Jcb.120.2.545 |
0.551 |
|
| 1992 |
Springer TA. The next cluster of differentiation (CD) workshop. Nature. 354: 415-6. PMID 1956408 DOI: 10.1038/354415A0 |
0.342 |
|
| 1992 |
de Fougerolles AR, Springer TA. Intercellular adhesion molecule 3, a third adhesion counter-receptor for lymphocyte function-associated molecule 1 on resting lymphocytes. The Journal of Experimental Medicine. 175: 185-90. PMID 1730916 DOI: 10.1084/JEM.175.1.185 |
0.442 |
|
| 1992 |
Mosser DM, Springer TA, Diamond MS. Leishmania promastigotes require opsonic complement to bind to the human leukocyte integrin Mac-1 (CD11b/CD18). The Journal of Cell Biology. 116: 511-20. PMID 1730765 DOI: 10.1083/jcb.116.2.511 |
0.546 |
|
| 1992 |
Staunton DE, Ockenhouse CF, Springer TA. Soluble intercellular adhesion molecule 1-immunoglobulin G1 immunoadhesin mediates phagocytosis of malaria-infected erythrocytes. The Journal of Experimental Medicine. 176: 1471-6. PMID 1383388 DOI: 10.1084/JEM.176.5.1471 |
0.337 |
|
| 1992 |
Vonderheide RH, Springer TA. Lymphocyte adhesion through very late antigen 4: Evidence for a novel binding site in the alternatively spliced domain of vascular cell adhesion molecule 1 and an additional α4 integrin counter-receptor on stimulated endothelium Journal of Experimental Medicine. 175: 1433-1442. PMID 1375259 DOI: 10.1084/Jem.175.6.1433 |
0.415 |
|
| 1992 |
Tözeren A, Sung KL, Sung LA, Dustin ML, Chan PY, Springer TA, Chien S. Micromanipulation of adhesion of a Jurkat cell to a planar bilayer membrane containing lymphocyte function-associated antigen 3 molecules. The Journal of Cell Biology. 116: 997-1006. PMID 1370839 DOI: 10.1083/Jcb.116.4.997 |
0.563 |
|
| 1992 |
Tözeren A, Mackie LH, Lawrence MB, Chan PY, Dustin ML, Springer TA. Micromanipulation of adhesion of phorbol 12-myristate-13-acetate-stimulated T lymphocytes to planar membranes containing intercellular adhesion molecule-1. Biophysical Journal. 63: 247-58. PMID 1358239 DOI: 10.1016/S0006-3495(92)81578-3 |
0.543 |
|
| 1992 |
Carpén O, Pallai P, Staunton DE, Springer TA. Association of intercellular adhesion molecule-1 (ICAM-1) with actin-containing cytoskeleton and alpha-actinin. The Journal of Cell Biology. 118: 1223-34. PMID 1355095 DOI: 10.1083/JCB.118.5.1223 |
0.412 |
|
| 1992 |
Chan PY, Springer TA. Effect of lengthening lymphocyte function-associated antigen 3 on adhesion to CD2. Molecular Biology of the Cell. 3: 157-66. PMID 1348006 DOI: 10.1091/MBC.3.2.157 |
0.464 |
|
| 1992 |
Ockenhouse CF, Betageri R, Springer TA, Staunton DE. Plasmodium falciparum-infected erythrocytes bind ICAM-1 at a site distinct from LFA-1, Mac-1, and human rhinovirus. Cell. 68: 63-9. PMID 1346257 DOI: 10.1016/0092-8674(92)90206-R |
0.36 |
|
| 1992 |
Springer TA. The next human leukocyte differentiation antigen workshop Immunology Today. 13: 6. DOI: 10.1016/0167-5699(92)90196-E |
0.362 |
|
| 1991 |
Springer TA. The sensation and regulation of interactions with the extracellular environment: the cell biology of lymphocyte adhesion receptors. Annual Review of Cell Biology. 6: 359-402. PMID 2275817 DOI: 10.1146/ANNUREV.CB.06.110190.002043 |
0.414 |
|
| 1991 |
Springer TA, Lasky LA. Cell adhesion. Sticky sugars for selectins. Nature. 349: 196-7. PMID 1987472 DOI: 10.1038/349196A0 |
0.346 |
|
| 1991 |
Springer TA. Cell adhesion. A birth certificate for CD2. Nature. 353: 704-5. PMID 1719420 DOI: 10.1038/353704A0 |
0.3 |
|
| 1991 |
Carpén O, Dustin ML, Springer TA, Swafford JA, Beckett LA, Caulfield JP. Motility and ultrastructure of large granular lymphocytes on lipid bilayers reconstituted with adhesion receptors LFA-1, ICAM-1, and two isoforms of LFA-3. The Journal of Cell Biology. 115: 861-71. PMID 1717493 DOI: 10.1083/Jcb.115.3.861 |
0.569 |
|
| 1991 |
Chan PY, Lawrence MB, Dustin ML, Ferguson LM, Golan DE, Springer TA. Influence of receptor lateral mobility on adhesion strengthening between membranes containing LFA-3 and CD2. The Journal of Cell Biology. 115: 245-55. PMID 1717480 DOI: 10.1083/Jcb.115.1.245 |
0.568 |
|
| 1991 |
Bevilacqua M, Butcher E, Furie B, Furie B, Gallatin M, Gimbrone M, Harlan J, Kishimoto K, Lasky L, McEver R, Paulson J, Rosen S, Seed B, Siegelman M, Springer T, et al. Selectins: A family of adhesion receptors Cell. 67: 233-233. PMID 1717161 DOI: 10.1016/0092-8674(91)90174-W |
0.358 |
|
| 1991 |
Dustin ML, Springer TA. Role of lymphocyte adhesion receptors in transient interactions and cell locomotion. Annual Review of Immunology. 9: 27-66. PMID 1716919 DOI: 10.1146/Annurev.Iy.09.040191.000331 |
0.564 |
|
| 1991 |
Schwartz MA, Ingber DE, Lawrence M, Springer TA, Lechene C. Multiple integrins share the ability to induce elevation of intracellular pH. Experimental Cell Research. 195: 533-5. PMID 1712734 DOI: 10.1016/0014-4827(91)90407-L |
0.442 |
|
| 1991 |
Larson RS, Hibbs ML, Springer TA. The leukocyte integrin LFA-1 reconstituted by cDNA transfection in a nonhematopoietic cell line is functionally active and not transiently regulated. Cell Regulation. 1: 359-67. PMID 1712636 DOI: 10.1091/MBC.1.4.359 |
0.412 |
|
| 1991 |
Lawrence MB, Springer TA. Leukocytes roll on a selectin at physiologic flow rates: distinction from and prerequisite for adhesion through integrins. Cell. 65: 859-73. PMID 1710173 DOI: 10.1016/0092-8674(91)90393-D |
0.347 |
|
| 1991 |
Hibbs ML, Jakes S, Stacker SA, Wallace RW, Springer TA. The cytoplasmic domain of the integrin lymphocyte function-associated antigen 1 beta subunit: sites required for binding to intercellular adhesion molecule 1 and the phorbol ester-stimulated phosphorylation site. The Journal of Experimental Medicine. 174: 1227-38. PMID 1682411 DOI: 10.1084/JEM.174.5.1227 |
0.427 |
|
| 1991 |
De Fougerolles AR, Stacker SA, Schwarting R, Springer TA. Characterization of ICAM-2 and evidence for a third counter-receptor for LFA-1 Journal of Experimental Medicine. 174: 253-267. PMID 1676048 DOI: 10.1084/JEM.174.1.253 |
0.404 |
|
| 1991 |
Diamond MS, Staunton DE, Marlin SD, Springer TA. Binding of the integrin Mac-1 (CD11b/CD18) to the third immunoglobulin-like domain of ICAM-1 (CD54) and its regulation by glycosylation. Cell. 65: 961-71. PMID 1675157 DOI: 10.1016/0092-8674(91)90548-D |
0.554 |
|
| 1991 |
Hibbs ML, Xu H, Stacker SA, Springer TA. Regulation of adhesion of ICAM-1 by the cytoplasmic domain of LFA-1 integrin beta subunit. Science (New York, N.Y.). 251: 1611-3. PMID 1672776 DOI: 10.1126/SCIENCE.1672776 |
0.48 |
|
| 1990 |
Hibbs ML, Selvaraj P, Carpén O, Springer TA, Kuster H, Jouvin MH, Kinet JP. Mechanisms for regulating expression of membrane isoforms of Fc gamma RIII (CD16). Science (New York, N.Y.). 246: 1608-11. PMID 2531918 DOI: 10.1126/SCIENCE.2531918 |
0.377 |
|
| 1990 |
Diamond MS, Staunton DE, de Fougerolles AR, Stacker SA, Garcia-Aguilar J, Hibbs ML, Springer TA. ICAM-1 (CD54): a counter-receptor for Mac-1 (CD11b/CD18). The Journal of Cell Biology. 111: 3129-39. PMID 1980124 DOI: 10.1083/Jcb.111.6.3129 |
0.583 |
|
| 1990 |
Springer TA. Adhesion receptors of the immune system. Nature. 346: 425-34. PMID 1974032 DOI: 10.1038/346425A0 |
0.351 |
|
| 1990 |
Staunton DE, Dustin ML, Erickson HP, Springer TA. The arrangement of the immunoglobulin-like domains of ICAM-1 and the binding sites for LFA-1 and rhinovirus. Cell. 61: 243-54. PMID 1970514 DOI: 10.1016/0092-8674(90)90805-O |
0.596 |
|
| 1990 |
Hibbs ML, Wardlaw AJ, Stacker SA, Anderson DC, Lee A, Roberts TM, Springer TA. Transfection of cells from patients with leukocyte adhesion deficiency with an integrin beta subunit (CD18) restores lymphocyte function-associated antigen-1 expression and function. The Journal of Clinical Investigation. 85: 674-81. PMID 1968909 DOI: 10.1172/Jci114491 |
0.381 |
|
| 1990 |
Marlin SD, Staunton DE, Springer TA, Stratowa C, Sommergruber W, Merluzzi VJ. A soluble form of intercellular adhesion molecule-1 inhibits rhinovirus infection. Nature. 344: 70-2. PMID 1968231 DOI: 10.1038/344070A0 |
0.403 |
|
| 1990 |
Wardlaw AJ, Hibbs ML, Stacker SA, Springer TA. Distinct mutations in two patients with leukocyte adhesion deficiency and their functional correlates. The Journal of Experimental Medicine. 172: 335-45. PMID 1694220 DOI: 10.1084/JEM.172.1.335 |
0.332 |
|
| 1989 |
Dustin ML, Garcia-Aguilar J, Hibbs ML, Larson RS, Stacker SA, Staunton DE, Wardlaw AJ, Springer TA. Structure and regulation of the leukocyte adhesion receptor LFA-1 and its counterreceptors, ICAM-1 and ICAM-2. Cold Spring Harbor Symposia On Quantitative Biology. 54: 753-65. PMID 2577025 DOI: 10.1101/Sqb.1989.054.01.089 |
0.519 |
|
| 1989 |
Kishimoto TK, Larson RS, Corbi AL, Dustin ML, Staunton DE, Springer TA. The leukocyte integrins. Advances in Immunology. 46: 149-82. PMID 2551146 DOI: 10.1016/S0065-2776(08)60653-7 |
0.536 |
|
| 1989 |
Staunton DE, Merluzzi VJ, Rothlein R, Barton R, Marlin SD, Springer TA. A cell adhesion molecule, ICAM-1, is the major surface receptor for rhinoviruses. Cell. 56: 849-53. PMID 2538244 DOI: 10.1016/0092-8674(89)90689-2 |
0.434 |
|
| 1989 |
Larson RS, Corbi AL, Berman L, Springer T. Primary structure of the leukocyte function-associated molecule-1 alpha subunit: an integrin with an embedded domain defining a protein superfamily. The Journal of Cell Biology. 108: 703-12. PMID 2537322 DOI: 10.1083/JCB.108.2.703 |
0.412 |
|
| 1989 |
Tonnesen MG, Anderson DC, Springer TA, Knedler A, Avdi N, Henson PM. Adherence of neutrophils to cultured human microvascular endothelial cells. Stimulation by chemotactic peptides and lipid mediators and dependence upon the Mac-1, LFA-1, p150,95 glycoprotein family. The Journal of Clinical Investigation. 83: 637-46. PMID 2521491 DOI: 10.1172/Jci113928 |
0.367 |
|
| 1989 |
Staunton DE, Dustin ML, Springer TA. Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1. Nature. 339: 61-4. PMID 2497351 DOI: 10.1038/339061A0 |
0.619 |
|
| 1989 |
Dustin ML, Springer TA. T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1. Nature. 341: 619-24. PMID 2477710 DOI: 10.1038/341619A0 |
0.572 |
|
| 1989 |
Hale LP, Martin ME, McCollum DE, Nunley JA, Springer TA, Singer KH, Haynes BF. Immunohistologic analysis of the distribution of cell adhesion molecules within the inflammatory synovial microenvironment. Arthritis and Rheumatism. 32: 22-30. PMID 2463839 DOI: 10.1002/ANR.1780320105 |
0.41 |
|
| 1989 |
Dustin ML, Olive D, Springer TA. Correlation of CD2 binding and functional properties of multimeric and monomeric lymphocyte function-associated antigen 3. The Journal of Experimental Medicine. 169: 503-17. PMID 2463330 DOI: 10.1084/Jem.169.2.503 |
0.541 |
|
| 1988 |
Staunton DE, Marlin SD, Stratowa C, Dustin ML, Springer TA. Primary structure of ICAM-1 demonstrates interaction between members of the immunoglobulin and integrin supergene families. Cell. 52: 925-33. PMID 3349522 DOI: 10.1016/0092-8674(88)90434-5 |
0.606 |
|
| 1988 |
Marlin SD, Springer TA. Purified intercellular adhesion molecule-1 (ICAM-1) is a ligand for lymphocyte function-associated antigen 1 (LFA-1). Cell. 51: 813-9. PMID 3315233 DOI: 10.1016/0092-8674(87)90104-8 |
0.451 |
|
| 1988 |
Corbi AL, Larson RS, Kishimoto TK, Springer TA, Morton CC. Chromosomal location of the genes encoding the leukocyte adhesion receptors LFA-1, Mac-1 and p150,95. Identification of a gene cluster involved in cell adhesion. The Journal of Experimental Medicine. 167: 1597-607. PMID 3284962 DOI: 10.1084/JEM.167.5.1597 |
0.314 |
|
| 1988 |
Makgoba MW, Sanders ME, Ginther Luce GE, Dustin ML, Springer TA, Clark EA, Mannoni P, Shaw S. ICAM-1 a ligand for LFA-1-dependent adhesion of B, T and myeloid cells. Nature. 331: 86-8. PMID 3277059 DOI: 10.1038/331086A0 |
0.594 |
|
| 1988 |
Dustin ML, Springer TA. Lymphocyte function-associated antigen-1 (LFA-1) interaction with intercellular adhesion molecule-1 (ICAM-1) is one of at least three mechanisms for lymphocyte adhesion to cultured endothelial cells. The Journal of Cell Biology. 107: 321-31. PMID 3134364 DOI: 10.1083/Jcb.107.1.321 |
0.563 |
|
| 1988 |
Dustin ML, Singer KH, Tuck DT, Springer TA. Adhesion of T lymphoblasts to epidermal keratinocytes is regulated by interferon gamma and is mediated by intercellular adhesion molecule 1 (ICAM-1). The Journal of Experimental Medicine. 167: 1323-40. PMID 3128630 DOI: 10.1084/Jem.167.4.1323 |
0.551 |
|
| 1988 |
Dustin ML, Staunton DE, Springer TA. Supergene families meet in the immune system. Immunology Today. 9: 213-5. PMID 3076418 DOI: 10.1016/0167-5699(88)91216-9 |
0.585 |
|
| 1988 |
Mentzer SJ, Rothlein R, Springer TA, Faller DV. Intercellular adhesion molecule-1 (ICAM-1) is involved in the cytolytic T lymphocyte interaction with a human synovial cell line. Journal of Cellular Physiology. 137: 173-8. PMID 3049628 DOI: 10.1002/jcp.1041370121 |
0.374 |
|
| 1988 |
Selvaraj P, Rosse WF, Silber R, Springer TA. The major Fc receptor in blood has a phosphatidylinositol anchor and is deficient in paroxysmal nocturnal haemoglobinuria. Nature. 333: 565-7. PMID 2967435 DOI: 10.1038/333565A0 |
0.372 |
|
| 1988 |
Makgoba MW, Sanders ME, Ginther Luce GE, Gugel EA, Dustin ML, Springer TA, Shaw S. Functional evidence that intercellular adhesion molecule-1 (ICAM-1) is a ligand for LFA-1-dependent adhesion in T cell-mediated cytotoxicity. European Journal of Immunology. 18: 637-40. PMID 2896596 DOI: 10.1002/Eji.1830180423 |
0.576 |
|
| 1988 |
Wang D, Liebowitz D, Wang F, Gregory C, Rickinson A, Larson R, Springer T, Kieff E. Epstein-Barr virus latent infection membrane protein alters the human B-lymphocyte phenotype: deletion of the amino terminus abolishes activity. Journal of Virology. 62: 4173-4184. PMID 2845129 DOI: 10.1128/Jvi.62.11.4173-4184.1988 |
0.347 |
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| 1988 |
SANDERS ME, MAKGOBA MW, SUSSMAN EH, LUCE GEG, SPRINGER TA, COSSMAN J, SHAW S. Spontaneous Rosetting of T Lymphocytes to Reed-Sternberg Cells Is Mediated by the CD2/LFA-3 and LFA-1/ICAM-1 Pathways of Antigen-Independent Adhesion Annals of the New York Academy of Sciences. 532: 436-438. DOI: 10.1111/j.1749-6632.1988.tb36367.x |
0.349 |
|
| 1988 |
MAKGOBA MW, SANDERS ME, LUCE GEG, GUGEL EA, DUSTIN ML, SPRINGER TA, SHAW S. Intercellular Adhesion Molecule-1 (ICAM-1) Monoclonal Antibody Inhibits Cytotoxic T Lymphocyte Recognition Annals of the New York Academy of Sciences. 532: 427-428. DOI: 10.1111/J.1749-6632.1988.Tb36364.X |
0.532 |
|
| 1987 |
Anderson DC, Springer TA. Leukocyte adhesion deficiency: an inherited defect in the Mac-1, LFA-1, and p150,95 glycoproteins. Annual Review of Medicine. 38: 175-94. PMID 3555290 DOI: 10.1146/ANNUREV.ME.38.020187.001135 |
0.388 |
|
| 1987 |
Dustin ML, Selvaraj P, Mattaliano RJ, Springer TA. Anchoring mechanisms for LFA-3 cell adhesion glycoprotein at membrane surface. Nature. 329: 846-8. PMID 3313053 DOI: 10.1038/329846A0 |
0.515 |
|
| 1987 |
Wallner BP, Frey AZ, Tizard R, Mattaliano RJ, Hession C, Sanders ME, Dustin ML, Springer TA. Primary structure of lymphocyte function-associated antigen 3 (LFA-3). The ligand of the T lymphocyte CD2 glycoprotein. The Journal of Experimental Medicine. 166: 923-32. PMID 3309127 DOI: 10.1084/Jem.166.4.923 |
0.553 |
|
| 1987 |
Selvaraj P, Dustin ML, Silber R, Low MG, Springer TA. Deficiency of lymphocyte function-associated antigen 3 (LFA-3) in paroxysmal nocturnal hemoglobinuria. Functional correlates and evidence for a phosphatidylinositol membrane anchor. The Journal of Experimental Medicine. 166: 1011-25. PMID 3309123 DOI: 10.1084/Jem.166.4.1011 |
0.564 |
|
| 1987 |
Springer TA, Dustin ML, Kishimoto TK, Marlin SD. The lymphocyte function-associated LFA-1, CD2, and LFA-3 molecules: cell adhesion receptors of the immune system. Annual Review of Immunology. 5: 223-52. PMID 3109455 DOI: 10.1146/Annurev.Iy.05.040187.001255 |
0.554 |
|
| 1987 |
Dustin ML, Sanders ME, Shaw S, Springer TA. Purified lymphocyte function-associated antigen 3 binds to CD2 and mediates T lymphocyte adhesion. The Journal of Experimental Medicine. 165: 677-92. PMID 3102676 DOI: 10.1084/Jem.165.3.677 |
0.535 |
|
| 1987 |
Plunkett ML, Sanders ME, Selvaraj P, Dustin ML, Springer TA. Rosetting of activated human T lymphocytes with autologous erythrocytes. Definition of the receptor and ligand molecules as CD2 and lymphocyte function-associated antigen 3 (LFA-3). The Journal of Experimental Medicine. 165: 664-76. PMID 3102675 DOI: 10.1084/Jem.165.3.664 |
0.545 |
|
| 1987 |
Miller LJ, Bainton DF, Borregaard N, Springer TA. Stimulated mobilization of monocyte Mac-1 and p150,95 adhesion proteins from an intracellular vesicular compartment to the cell surface. The Journal of Clinical Investigation. 80: 535-44. PMID 3038962 DOI: 10.1172/JCI113102 |
0.321 |
|
| 1987 |
Kishimoto TK, O'Connor K, Lee A, Roberts TM, Springer TA. Cloning of the beta subunit of the leukocyte adhesion proteins: homology to an extracellular matrix receptor defines a novel supergene family. Cell. 48: 681-90. PMID 3028646 DOI: 10.1016/0092-8674(87)90246-7 |
0.329 |
|
| 1987 |
Selvaraj P, Plunkett ML, Dustin M, Sanders ME, Shaw S, Springer TA. The T lymphocyte glycoprotein CD2 binds the cell surface ligand LFA-3. Nature. 326: 400-3. PMID 2951597 DOI: 10.1038/326400A0 |
0.565 |
|
| 1987 |
Tiefenthaler G, Hünig T, Dustin ML, Springer TA, Meuer SC. Purified lymphocyte function-associated antigen-3 and T11 target structure are active in CD2-mediated T cell stimulation. European Journal of Immunology. 17: 1847-50. PMID 2891540 DOI: 10.1002/Eji.1830171227 |
0.544 |
|
| 1987 |
Bainton DF, Miller LJ, Kishimoto TK, Springer TA. Leukocyte adhesion receptors are stored in peroxidase-negative granules of human neutrophils. The Journal of Experimental Medicine. 166: 1641-53. PMID 2824654 DOI: 10.1084/JEM.166.6.1641 |
0.334 |
|
| 1987 |
Pischel KD, Marlin SD, Springer TA, Woods VL, Bluestein HG. Polymorphism of lymphocyte function-associated antigen-1 demonstrated by a lupus patient's alloantiserum. The Journal of Clinical Investigation. 79: 1607-14. PMID 2438304 DOI: 10.1172/Jci112996 |
0.356 |
|
| 1987 |
Corbi AL, Miller LJ, O'Connor K, Larson RS, Springer TA. cDNA cloning and complete primary structure of the alpha subunit of a leukocyte adhesion glycoprotein, p150,95. The Embo Journal. 6: 4023-4028. DOI: 10.1002/j.1460-2075.1987.tb02746.x |
0.404 |
|
| 1986 |
Cardosa MJ, Gordon S, Hirsch S, Springer TA, Porterfield JS. Interaction of West Nile virus with primary murine macrophages: role of cell activation and receptors for antibody and complement. Journal of Virology. 57: 952-9. PMID 3951020 DOI: 10.1128/Jvi.57.3.952-959.1986 |
0.326 |
|
| 1986 |
Mentzer SJ, Bierer BE, Anderson DC, Springer TA, Burakoff SJ. Abnormal cytolytic activity of lymphocyte function-associated antigen-1-deficient human cytolytic T lymphocyte clones. The Journal of Clinical Investigation. 78: 1387-91. PMID 3534001 DOI: 10.1172/Jci112725 |
0.362 |
|
| 1986 |
Marlin SD, Morton CC, Anderson DC, Springer TA. LFA-1 immunodeficiency disease. Definition of the genetic defect and chromosomal mapping of alpha and beta subunits of the lymphocyte function-associated antigen 1 (LFA-1) by complementation in hybrid cells. The Journal of Experimental Medicine. 164: 855-67. PMID 3528378 DOI: 10.1084/JEM.164.3.855 |
0.361 |
|
| 1986 |
Rothlein R, Springer TA. The requirement for lymphocyte function-associated antigen 1 in homotypic leukocyte adhesion stimulated by phorbol ester. The Journal of Experimental Medicine. 163: 1132-49. PMID 3517218 DOI: 10.1084/JEM.163.5.1132 |
0.389 |
|
| 1986 |
Shaw S, Luce GE, Quinones R, Gress RE, Springer TA, Sanders ME. Two antigen-independent adhesion pathways used by human cytotoxic T-cell clones. Nature. 323: 262-4. PMID 3093887 DOI: 10.1038/323262a0 |
0.378 |
|
| 1986 |
Strassmann G, Somers SD, Springer TA, Adams DO, Hamilton TA. Biochemical models of interferon-γ-mediated macrophage activation: Independent regulation of lymphocyte function associated antigen (LFA)-1 and I-A antigen on murine peritoneal macrophages Cellular Immunology. 97: 110-120. PMID 3017574 DOI: 10.1016/0008-8749(86)90380-1 |
0.324 |
|
| 1986 |
Sastre L, Roman JM, Teplow DB, Dreyer WJ, Gee CE, Larson RS, Roberts TM, Springer TA. A partial genomic DNA clone for the alpha subunit of the mouse complement receptor type 3 and cellular adhesion molecule Mac-1. Proceedings of the National Academy of Sciences of the United States of America. 83: 5644-8. PMID 2942940 DOI: 10.1073/Pnas.83.15.5644 |
0.321 |
|
| 1985 |
Gaulton GN, Bangs J, Maddock S, Springer T, Eardley DD, Strom TB. Characterization of a monoclonal rat anti-mouse interleukin 2 (IL-2) receptor antibody and its use in the biochemical characterization of the murine IL-2 receptor. Clinical Immunology and Immunopathology. 36: 18-29. PMID 3924455 DOI: 10.1016/0090-1229(85)90035-2 |
0.316 |
|
| 1985 |
Anderson DC, Schmalsteig FC, Finegold MJ, Hughes BJ, Rothlein R, Miller LJ, Kohl S, Tosi MF, Jacobs RL, Waldrop TC, Goldman AS, Shearer WT, Springer TA. The Severe and Moderate Phenotypes of Heritable Mac-1, LFA-1 Deficiency: Their Quantitative Definition and Relation to Leukocyte Dysfunction and Clinical Features The Journal of Infectious Diseases. 152: 668-689. PMID 3900232 DOI: 10.1093/Infdis/152.4.668 |
0.323 |
|
| 1985 |
Springer TA, Rothlein R, Anderson DC, Burakoff SJ, Krensky AM. The function of LFA-1 in cell-mediated killing and adhesion: studies on heritable LFA-1, Mac-1 deficiency and on lymphoid cell self-aggregation. Advances in Experimental Medicine and Biology. 184: 311-22. PMID 3898754 DOI: 10.1007/978-1-4684-8326-0_21 |
0.385 |
|
| 1985 |
Strassmann G, Springer TA, Haskill SJ, Miraglia CC, Lanier LL, Adams DO. Antigens associated with the activation of murine mononuclear phagocytes in vivo: differential expression of lymphocyte function-associated antigen in the several stages of development. Cellular Immunology. 94: 265-75. PMID 3893748 DOI: 10.1016/0008-8749(85)90103-0 |
0.305 |
|
| 1985 |
Springer TA, Teplow DB, Dreyer WJ. Sequence homology of the LFA-1 and Mac-1 leukocyte adhesion glycoproteins and unexpected relation to leukocyte interferon. Nature. 314: 540-2. PMID 3887182 DOI: 10.1038/314540A0 |
0.39 |
|
| 1985 |
Hogarth PM, Walker ID, McKenzie IFC, Springer TA. The Ly-15 alloantigenic system: A genetically determined polymorphism of the murine lymphocyte function-associated antigen-1 molecule Proceedings of the National Academy of Sciences of the United States of America. 82: 526-530. PMID 3881766 DOI: 10.1073/PNAS.82.2.526 |
0.393 |
|
| 1985 |
Ross G, Thompson R, Walport M, Springer T, Watson J, Ward R, Lida J, Newman S, Harrison R, Lachmann P. Characterization of patients with an increased susceptibility to bacterial infections and a genetic deficiency of leukocyte membrane complement receptor type 3 and the related membrane antigen LFA-1 Blood. 66: 882-890. DOI: 10.1182/blood.v66.4.882.882 |
0.33 |
|
| 1984 |
Springer TA, Unkeless JC. Analysis of macrophage differentiation and function with monoclonal antibodies. Contemporary Topics in Immunobiology. 13: 1-31. PMID 6375951 DOI: 10.1007/978-1-4757-1445-6_1 |
0.307 |
|
| 1984 |
Dana N, Todd RF, Pitt J, Springer TA, Arnaout MA. Deficiency of a surface membrane glycoprotein (Mo1) in man. The Journal of Clinical Investigation. 73: 153-9. PMID 6361068 DOI: 10.1172/JCI111186 |
0.367 |
|
| 1984 |
Hemler ME, Sanchez-Madrid F, Flotte TJ, Krensky AM, Burakoff SJ, Bhan AK, Springer TA, Strominger JL. Glycoproteins of 210,000 and 130,000 m.w. on activated T cells: cell distribution and antigenic relation to components on resting cells and T cell lines. Journal of Immunology (Baltimore, Md. : 1950). 132: 3011-8. PMID 6327814 |
0.407 |
|
| 1984 |
Springer TA, Bhattacharya A, Cardoza JT, Sanchez-Madrid F. Monoclonal antibodies specific for rat IgG1, IgG2a, and IgG2b subclasses, and kappa chain monotypic and allotypic determinants: reagents for use with rat monoclonal antibodies. Hybridoma. 1: 257-73. PMID 6208128 DOI: 10.1089/HYB.1.1982.1.257 |
0.318 |
|
| 1984 |
Sanchez-Madrid F, Nagy JA, Robbins E, Simon P, Springer TA. A human leukocyte differentiation antigen family with distinct alpha-subunits and a common beta-subunit: the lymphocyte function-associated antigen (LFA-1), the C3bi complement receptor (OKM1/Mac-1), and the p150,95 molecule. The Journal of Experimental Medicine. 158: 1785-1803. PMID 6196430 DOI: 10.1084/JEM.158.6.1785 |
0.359 |
|
| 1984 |
Springer TA, Thompson WS, Miller LJ, Schmalstieg FC, Anderson DC. Inherited deficiency of the Mac-1, LFA-1, p150,95 glycoprotein family and its molecular basis. The Journal of Experimental Medicine. 160: 1901-18. PMID 6096477 DOI: 10.1084/jem.160.6.1901 |
0.355 |
|
| 1984 |
Ho MK, Springer TA. Preparation and use of monoclonal antimacrophage antibodies. Methods in Enzymology. 108: 313-24. PMID 6084796 DOI: 10.1016/S0076-6879(84)08098-8 |
0.309 |
|
| 1983 |
Beller DI, Springer TA, Schreiber RD. Anti-Mac-1 selectively inhibits the mouse and human type three complement receptor. The Journal of Experimental Medicine. 156: 1000-9. PMID 7153706 DOI: 10.1084/Jem.156.4.1000 |
0.32 |
|
| 1983 |
Sanchez-Madrid F, Davignon D, Martz E, Springer TA. Antigens involved in mouse cytolytic T-lymphocyte (CTL)-mediated killing: functional screening and topographic relationship. Cellular Immunology. 73: 1-11. PMID 6983917 DOI: 10.1016/0008-8749(82)90431-2 |
0.381 |
|
| 1983 |
Haines KA, Flotte TJ, Springer TA, Gigli I, Thorbecke GJ. Staining of Langerhans cells with monoclonal antibodies to macrophages and lymphoid cells Proceedings of the National Academy of Sciences of the United States of America. 80: 3448-3451. PMID 6574493 DOI: 10.1073/PNAS.80.11.3448 |
0.351 |
|
| 1983 |
Burakoff SJ, Clayberger C, Hemler M, Krensky AM, Reiss CS, Robbins E, Sanchez-Madrid F, Springer TA, Strominger JL, Ware CF. Cytotoxic T cells directed against HLA-DR antigens and their surface proteins. Diagnostic Immunology. 1: 116-9. PMID 6238749 |
0.41 |
|
| 1983 |
Sanchez-Madrid F, Simon P, Thompson S, Springer TA. Mapping of antigenic and functional epitopes on the alpha- and beta-subunits of two related mouse glycoproteins involved in cell interactions, LFA-1 and Mac-1. The Journal of Experimental Medicine. 158: 586-602. PMID 6193226 DOI: 10.1084/JEM.158.2.586 |
0.389 |
|
| 1983 |
Ware CF, Sanchez-Madrid F, Krensky AM, Burakoff SJ, Strominger JL, Springer TA. Human lymphocyte function associated antigen-1 (LFA-1): identification of multiple antigenic epitopes and their relationship to CTL-mediated cytotoxicity. Journal of Immunology (Baltimore, Md. : 1950). 131: 1182-8. PMID 6193178 |
0.454 |
|
| 1983 |
Ralph P, Harris P, Punjabi C, Welte K, Litcofsky P, Ho M, Rubin B, Moore M, Springer T. Lymphokine inducing "terminal differentiation" of the human monoblast leukemia line U937: a role for gamma interferon Blood. 62: 1169-1175. DOI: 10.1182/blood.v62.6.1169.1169 |
0.345 |
|
| 1982 |
Sanchez-Madrid F, Krensky AM, Ware CF, Robbins E, Strominger JL, Burakoff SJ, Springer TA. Three distinct antigens associated with human T-lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3. Proceedings of the National Academy of Sciences of the United States of America. 79: 7489-93. PMID 6984191 DOI: 10.1073/Pnas.79.23.7489 |
0.531 |
|
| 1982 |
Martz E, Davignon D, Kürzinger K, Springer TA. The molecular basis for cytolytic T lymphocyte function: analysis with blocking monoclonal antibodies. Advances in Experimental Medicine and Biology. 146: 447-68. PMID 6980570 DOI: 10.1007/978-1-4684-8959-0_27 |
0.401 |
|
| 1982 |
Springer TA, Davignon D, Ho MK, Kürzinger K, Martz E, Sanchez-Madrid F. LFA-1 and Lyt-2,3, molecules associated with T lymphocyte-mediated killing; and Mac-1, an LFA-1 homologue associated with complement receptor function. Immunological Reviews. 68: 171-95. PMID 6184305 DOI: 10.1111/J.1600-065X.1982.Tb01064.X |
0.32 |
|
| 1982 |
Kürzinger K, Ho MK, Springer TA. Structural homology of a macrophage differentiation antigen and an antigen involved in T-cell-mediated killing. Nature. 296: 668-70. PMID 6175907 DOI: 10.1038/296668A0 |
0.361 |
|
| 1981 |
Davignon D, Martz E, Reynolds T, Kürzinger K, Springer TA. Lymphocyte function-associated antigen 1 (LFA-1): a surface antigen distinct from Lyt-2,3 that participates in T lymphocyte-mediated killing. Proceedings of the National Academy of Sciences of the United States of America. 78: 4535-9. PMID 7027264 DOI: 10.1073/PNAS.78.7.4535 |
0.394 |
|
| 1979 |
Springer T, Galfré G, Secher DS, Milstein C. Mac-1: a macrophage differentiation antigen identified by monoclonal antibody. European Journal of Immunology. 9: 301-6. PMID 89034 DOI: 10.1002/Eji.1830090410 |
0.541 |
|
| 1979 |
Milstein C, Galfre G, Secher DS, Springer T. Monoclonal antibodies and cell surface antigens. Cell Biology International Reports. 3: 1-16. PMID 88272 DOI: 10.1016/0309-1651(79)90063-8 |
0.523 |
|
| 1978 |
Springer T, Galfre G, Secher D, Milstein C. Monoclonal xenogeneic antibodies to mouse leukocyte antigens: identification of macrophage-specific and other differentiation antigens. Current Topics in Microbiology and Immunology. 81: 45-50. PMID 688760 DOI: 10.1007/978-3-642-67448-8_7 |
0.551 |
|
| 1978 |
Springer T, Galfrè G, Secher DS, Milstein C. Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leukocyte differentiation antigens. European Journal of Immunology. 8: 539-51. PMID 81133 DOI: 10.1002/eji.1830080802 |
0.562 |
|
| 1977 |
Springer TA, Robb RJ, Terhorst C, Strominger JL. Submit and disulfide structure of monomeric and dimeric forms of detergent-soluble HLA antigens. The Journal of Biological Chemistry. 252: 4694-700. PMID 873911 |
0.559 |
|
| 1977 |
Strominger JL, Mann DL, Parham P, Robb R, Springer T, Terhorst C. Structure of HL-A A and B antigens isolated from cultured human lymphocytes. Cold Spring Harbor Symposia On Quantitative Biology. 41: 323-9. PMID 330091 DOI: 10.1101/Sqb.1977.041.01.038 |
0.624 |
|
| 1977 |
Springer TA, Kaufman JF, Siddoway LA, Mann DL, Strominger JL. Purification of HLA-linked B lymphocyte alloantigens in immunologically active form by preparative sodium dodecyl sulfate-gel electrophoresis and studies on their subunit association. The Journal of Biological Chemistry. 252: 6201-7. PMID 302259 |
0.368 |
|
| 1977 |
Springer TA, Kaufman JF, Terhorst C, Strominger JL. Purification and structural characterisation of human HLA-linked B-cell antigens. Nature. 268: 213-8. PMID 301990 DOI: 10.1038/268213A0 |
0.581 |
|
| 1977 |
Springer TA, Strominger JL. Detergent-soluble products of the HLA region. Transplantation Proceedings. 9: 21-8. PMID 300928 |
0.309 |
|
| 1977 |
Springer TA, Kaufman JF, Siddoway LA, Giphart M, Mann DL, Terhorst C, Strominger JL. Chemical and immunological characterization of HL-A linked B-lymphocyte alloantigens. Cold Spring Harbor Symposia On Quantitative Biology. 41: 387-96. PMID 70316 DOI: 10.1101/Sqb.1977.041.01.046 |
0.596 |
|
| 1977 |
Springer TA, Mann DL, DeFranco AL, Strominger JL. Detergent solubilization, purification, and separation of specificities of HLA antigens from a cultured human lymphoblastoid line, RPMI 4265. The Journal of Biological Chemistry. 252: 4682-93. PMID 68955 |
0.39 |
|
| 1976 |
Springer TA, Strominger JL. Detergent-soluble HLA antigens contain a hydrophilic region at the COOH-terminus and a penultimate hydrophobic region. Proceedings of the National Academy of Sciences of the United States of America. 73: 2481-5. PMID 781677 DOI: 10.1073/Pnas.73.7.2481 |
0.447 |
|
| 1974 |
Springer TA, Strominger JL, Mann D. Partial purification of detergent-soluble HL-A antigen and its cleavage by papain. Proceedings of the National Academy of Sciences of the United States of America. 71: 1539-43. PMID 4208551 DOI: 10.1073/Pnas.71.4.1539 |
0.434 |
|
| 1974 |
Strominger JL, Cresswell P, Grey H, Humphreys RE, Mann D, McCuneJ, Parham P, Robb R, Sanderson AR, Springer TA, Terhorst C, Turner MJ. The immunoglobulin-like structure of human histocompatibility antigens. Transplantation Reviews. 21: 126-43. PMID 4139785 DOI: 10.1111/J.1600-065X.1974.Tb01549.X |
0.727 |
|
| 1974 |
Cresswell P, Springer T, Strominger JL, Turner MJ, Grey HM, Kubo RT. Immunological identity of the small subunit of HL-A antigens and beta2-microglobulin and its turnover on the cell membrane. Proceedings of the National Academy of Sciences of the United States of America. 71: 2123-7. PMID 4134761 DOI: 10.1073/Pnas.71.5.2123 |
0.633 |
|
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