Year |
Citation |
Score |
2024 |
Chanez-Paredes SD, Abtahi S, Zha J, Li E, Marsischky G, Zuo L, Grey MJ, He W, Turner JR. Mechanisms underlying distinct subcellular localizations and regulation of epithelial long myosin light chain kinase (MLCK) splice variants. The Journal of Biological Chemistry. 105643. PMID 38199574 DOI: 10.1016/j.jbc.2024.105643 |
0.312 |
|
2022 |
Kaak JL, Lobo de Sá FD, Turner JR, Schulzke JD, Bücker R. Unraveling the intestinal epithelial barrier in cyanotoxin microcystin-treated Caco-2 cell monolayers. Annals of the New York Academy of Sciences. PMID 35883254 DOI: 10.1111/nyas.14870 |
0.311 |
|
2022 |
Kuo WT, Odenwald MA, Turner JR, Zuo L. Tight junction proteins occludin and ZO-1 as regulators of epithelial proliferation and survival. Annals of the New York Academy of Sciences. PMID 35580994 DOI: 10.1111/nyas.14798 |
0.3 |
|
2022 |
Zuo L, Kuo WT, Cao F, Chanez-Paredes SD, Zeve D, Mannam P, Jean-François L, Day A, Vallen Graham W, Sweat YY, Shashikanth N, Breault DT, Turner JR. Tacrolimus-binding protein FKBP8 directs myosin light chain kinase-dependent barrier regulation and is a potential therapeutic target in Crohn's disease. Gut. PMID 35537812 DOI: 10.1136/gutjnl-2021-326534 |
0.32 |
|
2021 |
Shashikanth N, Rizzo HE, Pongkorpsakol P, Heneghan JF, Turner JR. Correction: Electrophysiologic Analysis of Tight Junction Size and Charge Selectivity. Current Protocols. 1: e259. PMID 34495581 DOI: 10.1002/cpz1.259 |
0.662 |
|
2021 |
Shashikanth N, Rizzo HE, Pongkorpsakol P, Heneghan JF, Turner JR. Electrophysiologic Analysis of Tight Junction Size and Charge Selectivity. Current Protocols. 1: e143. PMID 34106526 DOI: 10.1002/cpz1.143 |
0.697 |
|
2020 |
Pongkorpsakol P, Turner JR, Zuo L. Culture of Intestinal Epithelial Cell Monolayers and Their Use in Multiplex Macromolecular Permeability Assays for In Vitro Analysis of Tight Junction Size Selectivity. Current Protocols in Immunology. 131: e112. PMID 33175441 DOI: 10.1002/cpim.112 |
0.731 |
|
2020 |
Cao F, Zhu L, Zhang J, Pongkorpsakol P, Kuo WT, Turner JR, Zhou Q, Wang Y, Chen F, Liu Y, Zuo L. Myosin light chain kinase is a potential target for hypopharyngeal cancer treatment. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 131: 110665. PMID 32920510 DOI: 10.1016/J.Biopha.2020.110665 |
0.719 |
|
2020 |
Labarta-Bajo L, Nilsen SP, Humphrey G, Schwartz T, Sanders K, Swafford A, Knight R, Turner JR, Zúñiga EI. Type I IFNs and CD8 T cells increase intestinal barrier permeability after chronic viral infection. The Journal of Experimental Medicine. 217. PMID 32880630 DOI: 10.1084/Jem.20192276 |
0.363 |
|
2020 |
Pai YC, Weng LT, Wei SC, Wu LL, Shih DQ, Targan SR, Turner JR, Yu LC. Gut microbial transcytosis induced by tumor necrosis factor-like 1A-dependent activation of a myosin light chain kinase splice variant contributes to IBD. Journal of Crohn's & Colitis. PMID 32770194 DOI: 10.1093/Ecco-Jcc/Jjaa165 |
0.45 |
|
2020 |
Kang JW, Yan J, Ranjan K, Zhang X, Turner JR, Abraham C. Myeloid Cell Expression of LACC1 is Required for Bacterial Clearance and Control of Intestinal Inflammation. Gastroenterology. PMID 32693188 DOI: 10.1053/J.Gastro.2020.07.024 |
0.409 |
|
2020 |
Yan J, Pandey SP, Barnes BJ, Turner JR, Abraham C. T Cell-Intrinsic IRF5 Regulates T Cell Signaling, Migration, and Differentiation and Promotes Intestinal Inflammation. Cell Reports. 31: 107820. PMID 32610123 DOI: 10.1016/J.Celrep.2020.107820 |
0.338 |
|
2020 |
Raju P, Shashikanth N, Tsai PY, Pongkorpsakol P, Chanez-Parades S, Steinhagen PR, Kuo WT, Singh G, Tsukita S, Turner JR. Inactivation of paracellular cation-selective claudin-2 channels attenuates immune-mediated experimental colitis in mice. The Journal of Clinical Investigation. PMID 32516134 DOI: 10.1172/Jci138697 |
0.753 |
|
2020 |
Zuo L, Kuo WT, Turner JR. Tight junctions as targets and effectors of mucosal immune homeostasis. Cellular and Molecular Gastroenterology and Hepatology. PMID 32304780 DOI: 10.1016/J.Jcmgh.2020.04.001 |
0.372 |
|
2020 |
Li HS, Xu SF, Sheng JY, Jiang ZH, Wang J, Ding N, Wang T, Odenwald MA, Turner JR, He WQ, Xu H, Zha JM. Quantification of Proliferative and Dead Cells in Enteroids. Journal of Visualized Experiments : Jove. PMID 32065148 DOI: 10.3791/60501 |
0.408 |
|
2020 |
Xie S, Jiang L, Wang M, Sun W, Yu S, Turner JR, Yu Q. Cadmium ingestion exacerbates Salmonella infection, with a loss of goblet cells through activation of Notch signaling pathways by ROS in the intestine. Journal of Hazardous Materials. 391: 122262. PMID 32062544 DOI: 10.1016/J.Jhazmat.2020.122262 |
0.389 |
|
2020 |
He WQ, Wang J, Sheng JY, Zha JM, Graham WV, Turner JR. Contributions of Myosin Light Chain Kinase to Regulation of Epithelial Paracellular Permeability and Mucosal Homeostasis. International Journal of Molecular Sciences. 21. PMID 32028590 DOI: 10.3390/Ijms21030993 |
0.648 |
|
2020 |
Shashikanth N, France MM, Xiao R, Southworth AP, Turner JR. Interclaudin Antagonism: A New Mechanism Of Tight Junction Dependent Barrier Regulation The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.02901 |
0.348 |
|
2020 |
Pai Y, Shih DQ, Targan SR, Turner J, Wei SC, Yu LC. Su1097 TL1A-MEDIATED BACTERIAL TRANSCYTOSIS BY A MLCK SPLICING VARIANT CONTRIBUTES TO INFLAMMATORY BOWEL DISEASE Gastroenterology. 158: S-508. DOI: 10.1016/S0016-5085(20)31949-1 |
0.332 |
|
2019 |
Kuo WT, Shen L, Zuo L, Shashikanth N, Ong MLDM, Wu L, Zha J, Edelblum KL, Wang Y, Wang Y, Nilsen SP, Turner JR. Inflammation-induced Occludin Downregulation Limits Epithelial Apoptosis by Suppressing Caspase 3 Expression. Gastroenterology. PMID 31401143 DOI: 10.1053/J.Gastro.2019.07.058 |
0.586 |
|
2019 |
Pandey SP, Yan J, Turner JR, Abraham C. Correction to: Reducing IRF5 expression attenuates colitis in mice, but impairs the clearance of intestinal pathogens. Mucosal Immunology. PMID 31182816 DOI: 10.1038/S41385-019-0179-8 |
0.332 |
|
2019 |
Richter JF, Hildner M, Schmauder R, Turner JR, Schumann M, Reiche J. Occludin knockdown is not sufficient to induce transepithelial macromolecule passage. Tissue Barriers. 1-14. PMID 31161924 DOI: 10.1080/21688370.2019.1608759 |
0.397 |
|
2019 |
Pandey SP, Yan J, Turner JR, Abraham C. Reducing IRF5 expression attenuates colitis in mice, but impairs the clearance of intestinal pathogens. Mucosal Immunology. PMID 31053739 DOI: 10.1038/S41385-019-0165-1 |
0.409 |
|
2019 |
Graham WV, He W, Marchiando AM, Zha J, Singh G, Li HS, Biswas A, Ong MLDM, Jiang ZH, Choi W, Zuccola H, Wang Y, Griffith J, Wu J, Rosenberg HJ, ... ... Turner JR, et al. Intracellular MLCK1 diversion reverses barrier loss to restore mucosal homeostasis. Nature Medicine. PMID 30936544 DOI: 10.1038/S41591-019-0393-7 |
0.811 |
|
2019 |
Nalle SC, Zuo L, Ong MLDM, Singh G, Worthylake AM, Choi W, Manresa MC, Southworth AP, Edelblum KL, Baker GJ, Joseph NE, Savage PA, Turner JR. Graft-versus-host disease propagation depends on increased intestinal epithelial tight junction permeability. The Journal of Clinical Investigation. PMID 30667372 DOI: 10.1172/Jci98554 |
0.805 |
|
2019 |
Tse CM, Yin J, Singh V, Sarker R, Lin R, Verkman AS, Turner JR, Donowitz M. cAMP stimulates SLC26A3 activity in human colon by a CFTR-dependent mechanism that does not require CFTR activity. Cellular and Molecular Gastroenterology and Hepatology. PMID 30659943 DOI: 10.1016/J.Jcmgh.2019.01.002 |
0.334 |
|
2018 |
Zha JM, Li HS, Lin Q, Kuo WT, Jiang ZH, Tsai PY, Ding N, Wu J, Xu SF, Wang YT, Pan J, Zhou XM, Chen K, Tao M, Odenwald MA, ... ... Turner JR, et al. Interleukin 22 Expands Transit-Amplifying Cells While Depleting Lgr5 Stem Cells via Inhibition of Wnt and Notch Signaling. Cellular and Molecular Gastroenterology and Hepatology. 7: 255-274. PMID 30686779 DOI: 10.1016/J.Jcmgh.2018.09.006 |
0.338 |
|
2018 |
Odenwald MA, Choi W, Kuo WT, Singh G, Sailer A, Wang Y, Shen L, Fanning AS, Turner JR. The scaffolding protein ZO-1 coordinates actomyosin and epithelial apical specializations in vitro and in vivo. The Journal of Biological Chemistry. PMID 30242130 DOI: 10.1074/Jbc.Ra118.003908 |
0.541 |
|
2018 |
Almansour K, Taverner A, Turner JR, Eggleston IM, Mrsny RJ. An intestinal paracellular pathway biased toward positively-charged macromolecules. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 30194947 DOI: 10.1016/J.Jconrel.2018.09.003 |
0.372 |
|
2018 |
Aihara E, Medina-Candelaria NM, Hanyu H, Matthis AL, Engevik KA, Gurniak CB, Witke W, Turner JR, Zhang T, Montrose MH. Cell injury triggers actin polymerization initiating epithelial restitution. Journal of Cell Science. PMID 30072444 DOI: 10.1242/Jcs.216317 |
0.382 |
|
2018 |
Hoffman JM, Sideri A, Ruiz JJ, Stavrakis D, Shih DQ, Turner JR, Pothoulakis C, Karagiannides I. Mesenteric Adipose-derived Stromal Cells From Crohn's Disease Patients Induce Protective Effects in Colonic Epithelial Cells and Mice With Colitis. Cellular and Molecular Gastroenterology and Hepatology. 6: 1-16. PMID 29928668 DOI: 10.1016/J.Jcmgh.2018.02.001 |
0.322 |
|
2018 |
Hu MD, Ethridge AD, Lipstein R, Kumar S, Wang Y, Jabri B, Turner JR, Edelblum KL. Epithelial IL-15 Is a Critical Regulator of γδ Intraepithelial Lymphocyte Motility within the Intestinal Mucosa. Journal of Immunology (Baltimore, Md. : 1950). PMID 29884699 DOI: 10.4049/Jimmunol.1701603 |
0.315 |
|
2018 |
Garber JJ, Mallick EM, Scanlon KM, Turner JR, Donnenberg MS, Leong JM, Snapper SB. Attaching-and-Effacing Pathogens Exploit Junction Regulatory Activities of N-WASP and SNX9 to Disrupt the Intestinal Barrier. Cellular and Molecular Gastroenterology and Hepatology. 5: 273-288. PMID 29675452 DOI: 10.1016/J.Jcmgh.2017.11.015 |
0.36 |
|
2018 |
Drolia R, Tenguria S, Durkes AC, Turner JR, Bhunia AK. Listeria Adhesion Protein Induces Intestinal Epithelial Barrier Dysfunction for Bacterial Translocation. Cell Host & Microbe. PMID 29606495 DOI: 10.1016/J.Chom.2018.03.004 |
0.438 |
|
2018 |
Krugliak Cleveland N, Huo D, Sadiq F, Sofia MA, Marks J, Cohen RD, Hanauer SB, Turner J, Hart J, Rubin DT. Assessment of Peri-Polyp Biopsies of Flat Mucosa in Patients with Inflammatory Bowel Disease. Gastrointestinal Endoscopy. PMID 29307473 DOI: 10.1016/J.Gie.2017.12.016 |
0.334 |
|
2018 |
Bacquie V, Olier M, Robbe-Masselot C, Ellero-Simatos S, Inczefi O, Sharon G, Bétoulières C, Theodorou V, Mazmanian S, Turner J, Mercier-Bonin M, Ferrier L. 136 - Impact of Epithelial Barrier Disruption on Mucus Layer and GUT Microbiota in Mice Gastroenterology. 154: S-37. DOI: 10.1016/S0016-5085(18)30594-8 |
0.308 |
|
2017 |
Shashikanth N, Yeruva S, Ong MLDM, Odenwald MA, Pavlyuk R, Turner JR. Epithelial Organization: The Gut and Beyond. Comprehensive Physiology. 7: 1497-1518. PMID 28915334 DOI: 10.1002/Cphy.C170003 |
0.342 |
|
2017 |
Edelblum KL, Sharon G, Singh G, Odenwald MA, Sailer A, Cao S, Ravens S, Thomsen I, El Bissati K, McLeod R, Dong C, Gurbuxani S, Prinz I, Mazmanian SK, Turner JR. The Microbiome Activates CD4 T-cell-mediated Immunity to Compensate for Increased Intestinal Permeability. Cellular and Molecular Gastroenterology and Hepatology. 4: 285-297. PMID 28795125 DOI: 10.1016/J.Jcmgh.2017.06.001 |
0.437 |
|
2017 |
Tsai PY, Zhang B, He WQ, Zha JM, Odenwald MA, Singh G, Tamura A, Shen L, Sailer A, Yeruva S, Kuo WT, Fu YX, Tsukita S, Turner JR. IL-22 Upregulates Epithelial Claudin-2 to Drive Diarrhea and Enteric Pathogen Clearance. Cell Host & Microbe. 21: 671-681.e4. PMID 28618266 DOI: 10.1016/J.Chom.2017.05.009 |
0.56 |
|
2017 |
Weber CR, Turner JR. Dynamic modeling of the tight junction pore pathway. Annals of the New York Academy of Sciences. PMID 28605031 DOI: 10.1111/Nyas.13374 |
0.318 |
|
2017 |
Ma Y, Yue J, Zhang Y, Shi C, Odenwald M, Liang WG, Wei Q, Goel A, Gou X, Zhang J, Chen SY, Tang WJ, Turner JR, Yang F, Liang H, et al. ACF7 regulates inflammatory colitis and intestinal wound response by orchestrating tight junction dynamics. Nature Communications. 8: 15375. PMID 28541346 DOI: 10.1038/Ncomms15375 |
0.43 |
|
2017 |
Buckley A, Turner JR. Cell Biology of Tight Junction Barrier Regulation and Mucosal Disease. Cold Spring Harbor Perspectives in Biology. PMID 28507021 DOI: 10.1101/Cshperspect.A029314 |
0.434 |
|
2017 |
Wang LC, Yu Q, Edwards V, Lin B, Qiu J, Turner JR, Stein DC, Song W. Neisseria gonorrhoeae infects the human endocervix by activating non-muscle myosin II-mediated epithelial exfoliation. Plos Pathogens. 13: e1006269. PMID 28406994 DOI: 10.1371/Journal.Ppat.1006269 |
0.392 |
|
2017 |
Choi W, Yeruva S, Turner JR. Contributions of intestinal epithelial barriers to health and disease. Experimental Cell Research. PMID 28342899 DOI: 10.1016/J.Yexcr.2017.03.036 |
0.349 |
|
2017 |
Peters SA, Edogawa S, Sundt WJ, Dyer RB, Dalenberg DA, Mazzone A, Singh RJ, Moses N, Smyrk TC, Weber C, Linden DR, MacNaughton WK, Turner JR, Camilleri M, Katzka DA, et al. Constipation-Predominant Irritable Bowel Syndrome Females Have Normal Colonic Barrier and Secretory Function. The American Journal of Gastroenterology. PMID 28323272 DOI: 10.1038/Ajg.2017.48 |
0.31 |
|
2017 |
France MM, Turner JR. The mucosal barrier at a glance. Journal of Cell Science. PMID 28062847 DOI: 10.1242/Jcs.193482 |
0.387 |
|
2017 |
Hoffman JM, Sideri A, Ruiz JJ, Turner JR, Pothoulakis C, Karagiannides I. Mesenteric Adipose Tissue Derived Stromal Cells from Crohn's Disease Patients Induce Lactoferrin-Dependent Protective Responses in Colonic Epithelial Cells and Mice with Colitis Gastroenterology. 152: S86-S87. DOI: 10.1016/S0016-5085(17)30638-8 |
0.351 |
|
2016 |
Blackwood BP, Wood DR, Yuan C, Nicolas J, De Plaen IG, Farrow KN, Chou P, Turner JR, Hunter CJ. A Role for cAMP and Protein Kinase A in Experimental Necrotizing Enterocolitis. The American Journal of Pathology. PMID 27939131 DOI: 10.1016/J.Ajpath.2016.10.014 |
0.388 |
|
2016 |
Wu RL, Vazquez-Roque MI, Carlson P, Burton D, Grover M, Camilleri M, Turner JR. Gluten-induced symptoms in diarrhea-predominant irritable bowel syndrome are associated with increased myosin light chain kinase activity and claudin-15 expression. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 27869798 DOI: 10.1038/Labinvest.2016.118 |
0.39 |
|
2016 |
Odenwald MA, Turner JR. The intestinal epithelial barrier: a therapeutic target? Nature Reviews. Gastroenterology & Hepatology. PMID 27848962 DOI: 10.1038/Nrgastro.2016.169 |
0.428 |
|
2016 |
Odenwald MA, Choi W, Buckley A, Shashikanth N, Joseph NE, Wang Y, Warren MH, Buschmann MM, Pavlyuk R, Hildebrand J, Margolis B, Fanning AS, Turner JR. ZO-1 interactions with F-actin and occludin direct epithelial polarization and single lumen specification in 3D culture. Journal of Cell Science. PMID 27802160 DOI: 10.1242/Jcs.188185 |
0.312 |
|
2016 |
Ronaghan NJ, Shang J, Iablokov V, Zaheer R, Colarusso P, Turner JR, MacNaughton WK. The serine protease-mediated increase in intestinal epithelial barrier function is dependent on occludin and requires an intact tight junction. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00441.2015. PMID 27492333 DOI: 10.1152/Ajpgi.00441.2015 |
0.441 |
|
2016 |
Choi VM, Herrou J, Hecht AL, Teoh WP, Turner JR, Crosson S, Wardenburg JB. Activation of Bacteroides fragilis toxin by a novel bacterial protease contributes to anaerobic sepsis in mice. Nature Medicine. PMID 27089515 DOI: 10.1038/Nm.4077 |
0.327 |
|
2016 |
Zha J, He W, Odenwald M, Turner J. Tu1831 MYPT1 Is a Critical Regulator of Intestinal Epithelial Cell Survival Gastroenterology. 150: S955. DOI: 10.1016/S0016-5085(16)33225-5 |
0.37 |
|
2016 |
Bacquié V, Olier M, Robbe-Masselot C, Inczefi O, Bétoulières C, Harkat C, Turner J, Theodorou V, Mercier-Bonin M, Ferrier L. Sa1418 Targeted Epithelial Disruption Impacts Colonic Mucus and Microbiota in Mice Gastroenterology. 150: S310. DOI: 10.1016/S0016-5085(16)31087-3 |
0.324 |
|
2015 |
Mir H, Meena AS, Chaudhry KK, Shukla PK, Gangwar R, Manda B, Padala MK, Shen L, Turner JR, Dietrich P, Dragatsis I, Rao R. Occludin deficiency promotes ethanol-induced disruption of colonic epithelial junctions, gut barrier dysfunction and liver damage in mice. Biochimica Et Biophysica Acta. PMID 26721332 DOI: 10.1016/J.Bbagen.2015.12.013 |
0.512 |
|
2015 |
Weber CR, Liang GH, Wang Y, Das S, Shen L, Yu AS, Nelson DJ, Turner JR. Claudin-2-dependent paracellular channels are dynamically gated. Elife. 4. PMID 26568313 DOI: 10.7554/Elife.09906 |
0.498 |
|
2015 |
Luther J, Garber JJ, Khalili H, Dave M, Bale SS, Jindal R, Motola DL, Luther S, Bohr S, Jeoung SW, Deshpande V, Singh G, Turner JR, Yarmush ML, Chung RT, et al. Hepatic Injury in Nonalcoholic Steatohepatitis Contributes to Altered Intestinal Permeability. Cellular and Molecular Gastroenterology and Hepatology. 1: 222-232. PMID 26405687 DOI: 10.1016/J.Jcmgh.2015.01.001 |
0.359 |
|
2015 |
Powers ME, Becker RE, Sailer A, Turner JR, Bubeck Wardenburg J. Synergistic Action of Staphylococcus aureus α-Toxin on Platelets and Myeloid Lineage Cells Contributes to Lethal Sepsis. Cell Host & Microbe. 17: 775-87. PMID 26067604 DOI: 10.1016/J.Chom.2015.05.011 |
0.31 |
|
2015 |
Lingaraju A, Long TM, Wang Y, Austin JR, Turner JR. Conceptual barriers to understanding physical barriers. Seminars in Cell & Developmental Biology. PMID 26003050 DOI: 10.1016/J.Semcdb.2015.04.008 |
0.356 |
|
2015 |
Setty M, Discepolo V, Abadie V, Kamhawi S, Mayassi T, Kent A, Ciszewski C, Maglio M, Kistner E, Bhagat G, Semrad C, Kupfer SS, Green PH, Guandalini S, Troncone R, ... ... Turner JR, et al. Distinct and Synergistic Contributions of Epithelial Stress and Adaptive Immunity to Functions of Intraepithelial Killer Cells and Active Celiac Disease. Gastroenterology. PMID 26001928 DOI: 10.1053/J.Gastro.2015.05.013 |
0.318 |
|
2015 |
Nalle SC, Turner JR. Intestinal barrier loss as a critical pathogenic link between inflammatory bowel disease and graft-versus-host disease. Mucosal Immunology. 8: 720-30. PMID 25943273 DOI: 10.1038/Mi.2015.40 |
0.794 |
|
2015 |
Edelblum KL, Singh G, Odenwald MA, Lingaraju A, El Bissati K, McLeod R, Sperling AI, Turner JR. γδ Intraepithelial Lymphocyte Migration Limits Transepithelial Pathogen Invasion and Systemic Disease in Mice. Gastroenterology. 148: 1417-26. PMID 25747597 DOI: 10.1053/J.Gastro.2015.02.053 |
0.391 |
|
2015 |
Pan J, Zhang L, Odenwald MA, Shen L, Turner JR, Bergelson JM. Expression of human decay-accelerating factor on intestinal epithelium of transgenic mice does not facilitate infection by the enteral route. Journal of Virology. 89: 4311-8. PMID 25653430 DOI: 10.1128/Jvi.03468-14 |
0.528 |
|
2015 |
Chen P, Stärkel P, Turner JR, Ho SB, Schnabl B. Dysbiosis-induced intestinal inflammation activates tumor necrosis factor receptor I and mediates alcoholic liver disease in mice. Hepatology (Baltimore, Md.). 61: 883-94. PMID 25251280 DOI: 10.1002/Hep.27489 |
0.378 |
|
2015 |
Weber CR, Liang GH, Wang Y, Das S, Shen L, Yu ASL, Nelson DJ, Turner JR. Author response: Claudin-2-dependent paracellular channels are dynamically gated Elife. DOI: 10.7554/Elife.09906.012 |
0.451 |
|
2015 |
Freddo AM, Grosse AS, Taniguchi K, Guysinger MN, Margolis B, Turner JR, Gumucio DL. 349 Villus Morphogenesis Re-Examined: Unique Cell Divisions Carve out Intestinal Villi Gastroenterology. 148: S-75. DOI: 10.1016/S0016-5085(15)30261-4 |
0.362 |
|
2014 |
Turner JR, Buschmann MM, Romero-Calvo I, Sailer A, Shen L. The role of molecular remodeling in differential regulation of tight junction permeability. Seminars in Cell & Developmental Biology. 36: 204-12. PMID 25263012 DOI: 10.1016/J.Semcdb.2014.09.022 |
0.571 |
|
2014 |
Chen MM, Zahs A, Brown MM, Ramirez L, Turner JR, Choudhry MA, Kovacs EJ. An alteration of the gut-liver axis drives pulmonary inflammation after intoxication and burn injury in mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. 307: G711-8. PMID 25104501 DOI: 10.1152/Ajpgi.00185.2014 |
0.311 |
|
2014 |
Nalle SC, Kwak HA, Edelblum KL, Joseph NE, Singh G, Khramtsova GF, Mortenson ED, Savage PA, Turner JR. Recipient NK cell inactivation and intestinal barrier loss are required for MHC-matched graft-versus-host disease. Science Translational Medicine. 6: 243ra87. PMID 24990882 DOI: 10.1126/Scitranslmed.3008941 |
0.8 |
|
2014 |
Wu LL, Peng WH, Kuo WT, Huang CY, Ni YH, Lu KS, Turner JR, Yu LC. Commensal bacterial endocytosis in epithelial cells is dependent on myosin light chain kinase-activated brush border fanning by interferon-γ. The American Journal of Pathology. 184: 2260-74. PMID 24911373 DOI: 10.1016/J.Ajpath.2014.05.003 |
0.42 |
|
2014 |
Ma K, Malhotra P, Soni V, Hedroug O, Annaba F, Dudeja A, Shen L, Turner JR, Khramtsova EA, Saksena S, Dudeja PK, Gill RK, Alrefai WA. Overactivation of intestinal SREBP2 in mice increases serum cholesterol. Plos One. 9: e84221. PMID 24465397 DOI: 10.1371/Journal.Pone.0084221 |
0.714 |
|
2014 |
He W, Zha J, Wang Y, Graham W, Rosenberg H, Turner JR. Tu1206 Unique Domains Within Long MLCK1 Direct Basal and TNF-Induced Trafficking to the Perijunctional Actomyosin Ring of Intestinal Epithelial Cells Gastroenterology. 146: S-783-S-784. DOI: 10.1016/S0016-5085(14)62827-4 |
0.585 |
|
2014 |
Krug SM, Bojarski C, Dames P, Turner JR, Fromm M, Schulzke JD. 410 Impaired Epithelial Barrier for Macromolecules in Ulcerative Colitis Is Caused by Downregulation of the Tricellular Tight Junction Protein Tricellulin, Mediated by the Interleukin-13 Receptor α2-Activated Pathway Gastroenterology. 146: S-88. DOI: 10.1016/S0016-5085(14)60318-8 |
0.357 |
|
2014 |
Khramtsova EA, Liang G, Weber CR, Tamura A, Shen L, Tsukita S, Turner JR. 362 Casein Kinase 2 (CK2) Inhibition Limits Damage-Induced and Immune-Mediated Colitis by Distinct Mechanisms Gastroenterology. 146: S-80. DOI: 10.1016/S0016-5085(14)60288-2 |
0.731 |
|
2014 |
Shen L, Lingaraju A, Wang Y, Edelblum KL, Khramtsova GF, Turner JR. 322 Occludin Limits Epithelial Survival by Inducing Caspase-3 Expression Gastroenterology. 146. DOI: 10.1016/S0016-5085(14)60263-8 |
0.482 |
|
2014 |
Freddo AM, Taniguchi K, Grosse AS, Margolis B, Turner JR, Gumucio DL. 250 Ezrin, an Apical Surface Protein, Functions in a Distinct Type of Cell Division in the Early Intestinal Epithelium to Aid Expansion of Luminal Surface Gastroenterology. 146: S-60. DOI: 10.1016/S0016-5085(14)60209-2 |
0.326 |
|
2014 |
He W, Zha J, Zhu M, Turner JR. 133 Myosin Phosphatase Is a Critical Regulator of Epithelial Homeostasis and Survival Whose Expression Is Downregulated in IBD Gastroenterology. 146: S-37. DOI: 10.1016/S0016-5085(14)60128-1 |
0.313 |
|
2014 |
Odenwald MA, Hecht AL, Turner JR. 130 A Dynamic Actin Cytoskeleton Promotes Tight Junction Reorganization and Epithelial Wound Closure In Vivo Gastroenterology. 146: S-36. DOI: 10.1016/S0016-5085(14)60125-6 |
0.316 |
|
2013 |
Buschmann MM, Shen L, Rajapakse H, Raleigh DR, Wang Y, Wang Y, Lingaraju A, Zha J, Abbott E, McAuley EM, Breskin LA, Wu L, Anderson K, Turner JR, Weber CR. Occludin OCEL-domain interactions are required for maintenance and regulation of the tight junction barrier to macromolecular flux. Molecular Biology of the Cell. 24: 3056-68. PMID 23924897 DOI: 10.1091/Mbc.E12-09-0688 |
0.675 |
|
2013 |
Odenwald MA, Turner JR. Intestinal permeability defects: is it time to treat? Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 11: 1075-83. PMID 23851019 DOI: 10.1016/J.Cgh.2013.07.001 |
0.412 |
|
2013 |
Su L, Nalle SC, Shen L, Turner ES, Singh G, Breskin LA, Khramtsova EA, Khramtsova G, Tsai PY, Fu YX, Abraham C, Turner JR. TNFR2 activates MLCK-dependent tight junction dysregulation to cause apoptosis-mediated barrier loss and experimental colitis. Gastroenterology. 145: 407-15. PMID 23619146 DOI: 10.1053/J.Gastro.2013.04.011 |
0.818 |
|
2013 |
Bergmann KR, Liu SX, Tian R, Kushnir A, Turner JR, Li HL, Chou PM, Weber CR, De Plaen IG. Bifidobacteria stabilize claudins at tight junctions and prevent intestinal barrier dysfunction in mouse necrotizing enterocolitis. The American Journal of Pathology. 182: 1595-606. PMID 23470164 DOI: 10.1016/J.Ajpath.2013.01.013 |
0.392 |
|
2013 |
Bouyer PG, Tang X, Weber CR, Shen L, Turner JR, Matthews JB. Capsaicin induces NKCC1 internalization and inhibits chloride secretion in colonic epithelial cells independently of TRPV1. American Journal of Physiology. Gastrointestinal and Liver Physiology. 304: G142-56. PMID 23139219 DOI: 10.1152/Ajpgi.00483.2011 |
0.568 |
|
2012 |
Nalle SC, Turner JR. Endothelial and epithelial barriers in graft-versus-host disease. Advances in Experimental Medicine and Biology. 763: 105-31. PMID 23397621 DOI: 10.1007/978-1-4614-4711-5_5 |
0.789 |
|
2012 |
Zahs A, Bird MD, Ramirez L, Turner JR, Choudhry MA, Kovacs EJ. Inhibition of long myosin light-chain kinase activation alleviates intestinal damage after binge ethanol exposure and burn injury. American Journal of Physiology. Gastrointestinal and Liver Physiology. 303: G705-12. PMID 22790598 DOI: 10.1152/Ajpgi.00157.2012 |
0.319 |
|
2012 |
Cunningham KE, Turner JR. Myosin light chain kinase: pulling the strings of epithelial tight junction function. Annals of the New York Academy of Sciences. 1258: 34-42. PMID 22731713 DOI: 10.1111/J.1749-6632.2012.06526.X |
0.436 |
|
2012 |
Hwang S, Zimmerman NP, Agle KA, Turner JR, Kumar SN, Dwinell MB. E-cadherin is critical for collective sheet migration and is regulated by the chemokine CXCL12 protein during restitution. The Journal of Biological Chemistry. 287: 22227-40. PMID 22549778 DOI: 10.1074/Jbc.M112.367979 |
0.373 |
|
2012 |
Edelblum KL, Shen L, Weber CR, Marchiando AM, Clay BS, Wang Y, Prinz I, Malissen B, Sperling AI, Turner JR. Dynamic migration of γδ intraepithelial lymphocytes requires occludin. Proceedings of the National Academy of Sciences of the United States of America. 109: 7097-102. PMID 22511722 DOI: 10.1073/Pnas.1112519109 |
0.806 |
|
2012 |
Zimmerman NP, Kumar SN, Turner JR, Dwinell MB. Cyclic AMP dysregulates intestinal epithelial cell restitution through PKA and RhoA. Inflammatory Bowel Diseases. 18: 1081-91. PMID 21993975 DOI: 10.1002/Ibd.21898 |
0.428 |
|
2012 |
Weber CR, Shen L, Nelson D, Yu A, Wang Y, Wang Y, Turner JR. 518 Patch Clamp Recordings Reveal Paracellular (Tight Junction) Ion Channels Gastroenterology. 142. DOI: 10.1016/S0016-5085(12)60409-0 |
0.453 |
|
2012 |
Gluth M, Weber CR, Mukai H, Baumgart DC, Turner JR, Theuring F, Fischer A. 212 The RHOA Effector Kinase PKN1 Modulates TNF-Induced Barrier Dysfunction in Intestinal Epithelial Cells Gastroenterology. 142: S-52. DOI: 10.1016/S0016-5085(12)60201-7 |
0.412 |
|
2012 |
Turner JR, Edelblum KL. 210 Intestinal Epithelial Barrier Dysfunction Induces IL-17 Production by γd Intraepithelial Lymphocytes Gastroenterology. 142: S-51-S-52. DOI: 10.1016/S0016-5085(12)60199-1 |
0.307 |
|
2012 |
Bradford EM, Turner ES, Turner JR. Understanding the epithelial barrierin inflammatory bowel disease Crohn's Disease and Ulcerative Colitis: From Epidemiology and Immunobiology to a Rational Diagnostic and Therapeutic Approach. 75-84. DOI: 10.1007/978-1-4614-0998-4_4 |
0.304 |
|
2011 |
Kolodziej LE, Lodolce JP, Chang JE, Schneider JR, Grimm WA, Bartulis SJ, Zhu X, Messer JS, Murphy SF, Reddy N, Turner JR, Boone DL. TNFAIP3 maintains intestinal barrier function and supports epithelial cell tight junctions. Plos One. 6: e26352. PMID 22031828 DOI: 10.1371/Journal.Pone.0026352 |
0.488 |
|
2011 |
Zahavi EE, Lieberman JA, Donnenberg MS, Nitzan M, Baruch K, Rosenshine I, Turner JR, Melamed-Book N, Feinstein N, Zlotkin-Rivkin E, Aroeti B. Bundle-forming pilus retraction enhances enteropathogenic Escherichia coli infectivity. Molecular Biology of the Cell. 22: 2436-47. PMID 21613538 DOI: 10.1091/Mbc.E11-01-0001 |
0.337 |
|
2011 |
Raleigh DR, Boe DM, Yu D, Weber CR, Marchiando AM, Bradford EM, Wang Y, Wu L, Schneeberger EE, Shen L, Turner JR. Occludin S408 phosphorylation regulates tight junction protein interactions and barrier function. The Journal of Cell Biology. 193: 565-82. PMID 21536752 DOI: 10.1083/Jcb.201010065 |
0.805 |
|
2011 |
Piontek J, Fritzsche S, Cording J, Richter S, Hartwig J, Walter M, Yu D, Turner JR, Gehring C, Rahn HP, Wolburg H, Blasig IE. Elucidating the principles of the molecular organization of heteropolymeric tight junction strands. Cellular and Molecular Life Sciences : Cmls. 68: 3903-18. PMID 21533891 DOI: 10.1007/S00018-011-0680-Z |
0.454 |
|
2011 |
Fu J, Wei B, Wen T, Johansson ME, Liu X, Bradford E, Thomsson KA, McGee S, Mansour L, Tong M, McDaniel JM, Sferra TJ, Turner JR, Chen H, Hansson GC, et al. Loss of intestinal core 1-derived O-glycans causes spontaneous colitis in mice. The Journal of Clinical Investigation. 121: 1657-66. PMID 21383503 DOI: 10.1172/Jci45538 |
0.313 |
|
2011 |
Guan Y, Watson AJ, Marchiando AM, Bradford E, Shen L, Turner JR, Montrose MH. Redistribution of the tight junction protein ZO-1 during physiological shedding of mouse intestinal epithelial cells. American Journal of Physiology. Cell Physiology. 300: C1404-14. PMID 21346149 DOI: 10.1152/Ajpcell.00270.2010 |
0.794 |
|
2011 |
Graham WV, Magis AT, Bailey KM, Turner JR, Ostrov DA. Crystallization and preliminary X-ray analysis of the human long myosin light-chain kinase 1-specific domain IgCAM3. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 221-3. PMID 21301090 DOI: 10.1107/S1744309110050323 |
0.588 |
|
2011 |
Marchiando AM, Shen L, Graham WV, Edelblum KL, Duckworth CA, Guan Y, Montrose MH, Turner JR, Watson AJ. The epithelial barrier is maintained by in vivo tight junction expansion during pathologic intestinal epithelial shedding. Gastroenterology. 140: 1208-1218.e1-2. PMID 21237166 DOI: 10.1053/J.Gastro.2011.01.004 |
0.82 |
|
2011 |
Paschoud S, Yu D, Pulimeno P, Jond L, Turner JR, Citi S. Cingulin and paracingulin show similar dynamic behaviour, but are recruited independently to junctions. Molecular Membrane Biology. 28: 123-35. PMID 21166484 DOI: 10.3109/09687688.2010.538937 |
0.481 |
|
2011 |
Lin R, Murtazina R, Cha B, Chakraborty M, Sarker R, Chen TE, Lin Z, Hogema BM, de Jonge HR, Seidler U, Turner JR, Li X, Kovbasnjuk O, Donowitz M. D-glucose acts via sodium/glucose cotransporter 1 to increase NHE3 in mouse jejunal brush border by a Na+/H+ exchange regulatory factor 2-dependent process. Gastroenterology. 140: 560-71. PMID 20977906 DOI: 10.1053/J.Gastro.2010.10.042 |
0.344 |
|
2011 |
Shen L, Weber CR, Raleigh DR, Yu D, Turner JR. Tight junction pore and leak pathways: a dynamic duo. Annual Review of Physiology. 73: 283-309. PMID 20936941 DOI: 10.1146/annurev-physiol-012110-142150 |
0.701 |
|
2011 |
Zimmerman NP, Turner JR, Dwinell MB. CAMP Abrogates Intestinal Epithelial Restitution Through PKA-Dependent Inhibition of Actin Remodeling Gastroenterology. 140: S-652. DOI: 10.1016/S0016-5085(11)62702-9 |
0.377 |
|
2011 |
Nalle SC, Joseph NE, Savage PA, Turner JR. Intestinal Damage and Myosin Light Chain Kinase (MLCK)-Dependent Epithelial Barrier Dysfunction Are Vital to Minor Mismatch Graft-Versus-Host Disease Gastroenterology. 140: S-167. DOI: 10.1016/S0016-5085(11)60677-X |
0.792 |
|
2011 |
Edelblum KL, Shen L, Marchiando AM, Wang Y, Sperling AI, Turner JR. Occludin Regulates γδ Intraepithelial Lymphocyte Migration In Vivo Gastroenterology. 140: S-132. DOI: 10.1016/S0016-5085(11)60540-4 |
0.782 |
|
2011 |
Weber CR, Shen L, Wu L, Wang Y, Turner JR. Occludin is Required for Tumor Necrosis Factor (TNF)-Mediated Regulation of Tight Junction (TJ) Barrier Function Gastroenterology. 140: S-64. DOI: 10.1016/S0016-5085(11)60262-X |
0.531 |
|
2010 |
Turner HL, Turner JR. Good fences make good neighbors: Gastrointestinal mucosal structure. Gut Microbes. 1: 22-29. PMID 21327113 DOI: 10.4161/Gmic.1.1.11427 |
0.317 |
|
2010 |
Royan SV, Jones RM, Koutsouris A, Roxas JL, Falzari K, Weflen AW, Kim A, Bellmeyer A, Turner JR, Neish AS, Rhee KJ, Viswanathan VK, Hecht GA. Enteropathogenic E. coli non-LEE encoded effectors NleH1 and NleH2 attenuate NF-κB activation. Molecular Microbiology. 78: 1232-45. PMID 21091507 DOI: 10.1111/J.1365-2958.2010.07400.X |
0.345 |
|
2010 |
Li H, Liu XS, Yang X, Wang Y, Wang Y, Turner JR, Liu X. Phosphorylation of CLIP-170 by Plk1 and CK2 promotes timely formation of kinetochore-microtubule attachments. The Embo Journal. 29: 2953-65. PMID 20664522 DOI: 10.1038/Emboj.2010.174 |
0.323 |
|
2010 |
Rajapakse HE, Gahlaut N, Mohandessi S, Yu D, Turner JR, Miller LW. Time-resolved luminescence resonance energy transfer imaging of protein-protein interactions in living cells. Proceedings of the National Academy of Sciences of the United States of America. 107: 13582-7. PMID 20643966 DOI: 10.1073/Pnas.1002025107 |
0.444 |
|
2010 |
Lissner S, Nold L, Hsieh CJ, Turner JR, Gregor M, Graeve L, Lamprecht G. Activity and PI3-kinase dependent trafficking of the intestinal anion exchanger downregulated in adenoma depend on its PDZ interaction and on lipid rafts. American Journal of Physiology. Gastrointestinal and Liver Physiology. 299: G907-20. PMID 20634435 DOI: 10.1152/Ajpgi.00191.2010 |
0.381 |
|
2010 |
Lee G, Goretsky T, Managlia E, Dirisina R, Singh AP, Brown JB, May R, Yang GY, Ragheb JW, Evers BM, Weber CR, Turner JR, He XC, Katzman RB, Li L, et al. Phosphoinositide 3-kinase signaling mediates beta-catenin activation in intestinal epithelial stem and progenitor cells in colitis. Gastroenterology. 139: 869-81, 881.e1-9. PMID 20580720 DOI: 10.1053/J.Gastro.2010.05.037 |
0.333 |
|
2010 |
Yu D, Marchiando AM, Weber CR, Raleigh DR, Wang Y, Shen L, Turner JR. MLCK-dependent exchange and actin binding region-dependent anchoring of ZO-1 regulate tight junction barrier function. Proceedings of the National Academy of Sciences of the United States of America. 107: 8237-41. PMID 20404178 DOI: 10.1073/Pnas.0908869107 |
0.816 |
|
2010 |
Marchiando AM, Shen L, Graham WV, Weber CR, Schwarz BT, Austin JR, Raleigh DR, Guan Y, Watson AJ, Montrose MH, Turner JR. Caveolin-1-dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo. The Journal of Cell Biology. 189: 111-26. PMID 20351069 DOI: 10.1083/Jcb.200902153 |
0.818 |
|
2010 |
Weber CR, Raleigh DR, Su L, Shen L, Sullivan EA, Wang Y, Turner JR. Epithelial myosin light chain kinase activation induces mucosal interleukin-13 expression to alter tight junction ion selectivity. The Journal of Biological Chemistry. 285: 12037-46. PMID 20177070 DOI: 10.1074/Jbc.M109.064808 |
0.715 |
|
2010 |
Raleigh DR, Marchiando AM, Zhang Y, Shen L, Sasaki H, Wang Y, Long M, Turner JR. Tight junction-associated MARVEL proteins marveld3, tricellulin, and occludin have distinct but overlapping functions. Molecular Biology of the Cell. 21: 1200-13. PMID 20164257 DOI: 10.1091/Mbc.E09-08-0734 |
0.793 |
|
2010 |
Marchiando AM, Graham WV, Turner JR. Epithelial barriers in homeostasis and disease. Annual Review of Pathology. 5: 119-44. PMID 20078218 DOI: 10.1146/Annurev.Pathol.4.110807.092135 |
0.817 |
|
2010 |
Chen L, Park SM, Turner JR, Peter ME. Cell death in the colonic epithelium during inflammatory bowel diseases: CD95/Fas and beyond. Inflammatory Bowel Diseases. 16: 1071-6. PMID 20049945 DOI: 10.1002/Ibd.21191 |
0.328 |
|
2010 |
Park SM, Chen L, Zhang M, Ashton-Rickardt P, Turner JR, Peter ME. CD95 is cytoprotective for intestinal epithelial cells in colitis. Inflammatory Bowel Diseases. 16: 1063-70. PMID 20049944 DOI: 10.1002/Ibd.21195 |
0.329 |
|
2010 |
Tang Y, Clayburgh DR, Mittal N, Goretsky T, Dirisina R, Zhang Z, Kron M, Ivancic D, Katzman RB, Grimm G, Lee G, Fryer J, Nusrat A, Turner JR, Barrett TA. Epithelial NF-kappaB enhances transmucosal fluid movement by altering tight junction protein composition after T cell activation. The American Journal of Pathology. 176: 158-67. PMID 20008138 DOI: 10.2353/Ajpath.2010.090548 |
0.676 |
|
2010 |
Mykoniatis A, Shen L, Fedor-Chaiken M, Tang J, Tang X, Worrell RT, Delpire E, Turner JR, Matlin KS, Bouyer P, Matthews JB. Phorbol 12-myristate 13-acetate-induced endocytosis of the Na-K-2Cl cotransporter in MDCK cells is associated with a clathrin-dependent pathway. American Journal of Physiology. Cell Physiology. 298: C85-97. PMID 19864322 DOI: 10.1152/Ajpcell.00118.2009 |
0.568 |
|
2010 |
Nalle SC, Savage PA, Turner JR. Total Body Irradiation Creates a Proinflammatory Milieu That Is Required for Minor, but Not Major, Mismatch Graft-Versus-Host-Disease. Blood. 116: 3736-3736. DOI: 10.1182/Blood.V116.21.3736.3736 |
0.763 |
|
2010 |
Qi W, Wasland K, Weber CR, Wali RK, Turner JR, Roy HK, Savkovic SD. M1944 Tumor Suppressor FOXO3 Regulates Proliferation of Intestinal Epithelial Cells Gastroenterology. 138: S-444. DOI: 10.1016/S0016-5085(10)62054-9 |
0.328 |
|
2010 |
Qi W, Jarrar A, Weber CR, Turner JR, Savkovic SD. M1840 Activity of Foxo Family Transcriptional Factors is Diminished in Inflamed Intestinal Epithelia Gastroenterology. 138: S-430. DOI: 10.1016/S0016-5085(10)61983-X |
0.396 |
|
2010 |
Lodolce JP, Kolodziej L, Chang J, Schneider JR, Messer JS, Turner JR, Boone DL. M1817 Regulation of Intestinal Permeability and Epithelial Cell Tight Junctions by the Ubiquitin-Editing Enzyme TNFAIP3 Gastroenterology. 138: S-425. DOI: 10.1016/S0016-5085(10)61960-9 |
0.342 |
|
2010 |
Samak G, Turner JR, Rao R(. S1778 Intracellular Calcium and Myosin Light Chain Kinase (MLCK) Activation are Involved in the Mechanism of Dextran Sodium Sulfate (DSS)-Induced Tight Junction (TJ) Disruption in CACO-2 Cell Monolayers Gastroenterology. 138: S-272. DOI: 10.1016/S0016-5085(10)61249-8 |
0.354 |
|
2010 |
Edelblum KL, Marchiando AM, Shen L, Wang Y, Sperling AI, Turner JR. 578 Tight Junction Protein Expression by γδ IELs Regulates Gastrointestinal Lymphocyte-Epithelial Interactions Gastroenterology. 138: S-82. DOI: 10.1016/S0016-5085(10)60373-3 |
0.792 |
|
2009 |
Nalle SC, Turner JR. Menetrier's disease therapy: rebooting mucosal signaling. Science Translational Medicine. 1: 8ps10. PMID 20368184 DOI: 10.1126/Scitranslmed.3000438 |
0.758 |
|
2009 |
Shen L, Su L, Turner JR. Mechanisms and functional implications of intestinal barrier defects. Digestive Diseases (Basel, Switzerland). 27: 443-9. PMID 19897958 DOI: 10.1159/000233282 |
0.583 |
|
2009 |
Turner JR. Intestinal mucosal barrier function in health and disease. Nature Reviews. Immunology. 9: 799-809. PMID 19855405 DOI: 10.1038/Nri2653 |
0.394 |
|
2009 |
Chen B, Yates E, Huang Y, Kogut P, Ma L, Turner JR, Tao Y, Camoretti-Mercado B, Lang D, Svensson EC, Garcia JG, Gruber PJ, Morrisey EE, Solway J. Alternative promoter and GATA5 transcripts in mouse. American Journal of Physiology. Gastrointestinal and Liver Physiology. 297: G1214-22. PMID 19779014 DOI: 10.1152/Ajpgi.00165.2009 |
0.303 |
|
2009 |
Esmaili A, Nazir SF, Borthakur A, Yu D, Turner JR, Saksena S, Singla A, Hecht GA, Alrefai WA, Gill RK. Enteropathogenic Escherichia coli Infection Inhibits Intestinal Serotonin Transporter Function and Expression Gastroenterology. 137: 2074-2083. PMID 19747920 DOI: 10.1053/J.Gastro.2009.09.002 |
0.485 |
|
2009 |
Snoeks L, Weber CR, Wasland K, Turner JR, Vainder C, Qi W, Savkovic SD. Tumor suppressor FOXO3 participates in the regulation of intestinal inflammation. Laboratory Investigation; a Journal of Technical Methods and Pathology. 89: 1053-62. PMID 19636295 DOI: 10.1038/Labinvest.2009.66 |
0.439 |
|
2009 |
Graham WV, Marchiando AM, Shen L, Turner JR. No static at all. Annals of the New York Academy of Sciences. 1165: 314-22. PMID 19538322 DOI: 10.1111/J.1749-6632.2009.04050.X |
0.815 |
|
2009 |
Lamprecht G, Gaco V, Turner JR, Natour D, Gregor M. Regulation of the intestinal anion exchanger DRA (downregulated in adenoma). Annals of the New York Academy of Sciences. 1165: 261-6. PMID 19538314 DOI: 10.1111/J.1749-6632.2009.04044.X |
0.399 |
|
2009 |
Lamprecht G, Hsieh CJ, Lissner S, Nold L, Heil A, Gaco V, Schäfer J, Turner JR, Gregor M. Intestinal anion exchanger down-regulated in adenoma (DRA) is inhibited by intracellular calcium. The Journal of Biological Chemistry. 284: 19744-53. PMID 19447883 DOI: 10.1074/Jbc.M109.004127 |
0.371 |
|
2009 |
Nalle SC, Turner JR. Epithelium, tear down this wall! Cell Host & Microbe. 5: 1-2. PMID 19154980 DOI: 10.1016/J.Chom.2008.12.008 |
0.773 |
|
2009 |
Mukherjee A, Morosky SA, Shen L, Weber CR, Turner JR, Kim KS, Wang T, Coyne CB. Retinoic acid-induced gene-1 (RIG-I) associates with the actin cytoskeleton via caspase activation and recruitment domain-dependent interactions. The Journal of Biological Chemistry. 284: 6486-94. PMID 19122199 DOI: 10.1074/Jbc.M807547200 |
0.573 |
|
2009 |
Suzuki T, Elias BC, Seth A, Shen L, Turner JR, Giorgianni F, Desiderio D, Guntaka R, Rao R. PKC eta regulates occludin phosphorylation and epithelial tight junction integrity. Proceedings of the National Academy of Sciences of the United States of America. 106: 61-6. PMID 19114660 DOI: 10.1073/Pnas.0802741106 |
0.561 |
|
2009 |
Liu S, Yang W, Shen L, Turner JR, Coyne CB, Wang T. Tight junction proteins claudin-1 and occludin control hepatitis C virus entry and are downregulated during infection to prevent superinfection. Journal of Virology. 83: 2011-4. PMID 19052094 DOI: 10.1128/Jvi.01888-08 |
0.477 |
|
2009 |
Su L, Shen L, Clayburgh DR, Nalle SC, Sullivan EA, Meddings JB, Abraham C, Turner JR. Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis. Gastroenterology. 136: 551-63. PMID 19027740 DOI: 10.1053/J.Gastro.2008.10.081 |
0.811 |
|
2009 |
Elias BC, Suzuki T, Seth A, Giorgianni F, Kale G, Shen L, Turner JR, Naren A, Desiderio DM, Rao R. Phosphorylation of Tyr-398 and Tyr-402 in occludin prevents its interaction with ZO-1 and destabilizes its assembly at the tight junctions. The Journal of Biological Chemistry. 284: 1559-69. PMID 19017651 DOI: 10.1074/Jbc.M804783200 |
0.539 |
|
2009 |
Wroblewski LE, Shen L, Ogden S, Romero-Gallo J, Lapierre LA, Israel DA, Turner JR, Peek RM. Helicobacter pylori dysregulation of gastric epithelial tight junctions by urease-mediated myosin II activation. Gastroenterology. 136: 236-46. PMID 18996125 DOI: 10.1053/J.Gastro.2008.10.011 |
0.544 |
|
2009 |
Cooney R, Jewell D, Papadakis KA, Skrypnyk IN, Zeitz M, Shen L, Su L, Turner JR, Hering NA, Schulzke J, Blumberg RS, Siegmund B, Vatn MH, Dietrich CF, Marth T, et al. Contents Vol. 27, 2009 Digestive Diseases. 27. DOI: 10.1159/000257418 |
0.415 |
|
2009 |
Cooney R, Jewell D, Papadakis KA, Skrypnyk IN, Zeitz M, Shen L, Su L, Turner JR, Hering NA, Schulzke J, Blumberg RS, Siegmund B, Vatn MH, Dietrich CF, Marth T, et al. Subject Index Vol. 27, 2009 Digestive Diseases. 27: 597-598. DOI: 10.1159/000257417 |
0.414 |
|
2009 |
Snoeks L, Wasland K, Weber CR, Turner JR, Savkovic SD. W1668 Tumor Suppressor FOXO3A Participates in the Regulation of Intestinal Inflammation Gastroenterology. 136: A-713-A-714. DOI: 10.1016/S0016-5085(09)63292-3 |
0.315 |
|
2009 |
Lissner S, Graeve L, Turner JR, Gregor M, Lamprecht G. T1733 The Intestinal Anion Exchanger DRA (Down Regulated in Adenoma) Is Partially Localised Within Lipid Rafts Gastroenterology. 136: A-568. DOI: 10.1016/S0016-5085(09)62614-7 |
0.303 |
|
2009 |
Weber CR, Raleigh DR, Wang Y, Turner JR. T1725 Interleukin 13 (IL-13) and Tumor Necrosis Factor (TNF) Affect Distinct Components of the Tight Junction Barrier By Differing Mechanisms Gastroenterology. 136: A-566-A-567. DOI: 10.1016/S0016-5085(09)62606-8 |
0.541 |
|
2009 |
Graham W, Rosenberg HJ, Turner JR. S1768 Multiple Protein Domains Direct Myosin Light Chain Kinase Isoform 1 (MLCK1) to the Tight Junction in Epithelial Cells Gastroenterology. 136: A-266. DOI: 10.1016/S0016-5085(09)61211-7 |
0.595 |
|
2009 |
Raleigh DR, Zhang Y, Marchiando AM, Wang Y, Shen L, Long M, Turner JR. S1757 TAMPs: A Tight Junction Protein Family with Non-Redundant Functions Gastroenterology. 136: A-264. DOI: 10.1016/S0016-5085(09)61201-4 |
0.764 |
|
2009 |
Mykoniatis A, Shen L, Tang J, Tang X, Turner JR, Matlin KS, Bouyer P, Matthews JB. 884 Regulation of NKCC1 Surface Expression By PKC Involves Dynamin II and Clathrin-Dependent Endocytic Machinery Gastroenterology. 136: A-136. DOI: 10.1016/S0016-5085(09)60613-2 |
0.47 |
|
2009 |
Su L, Nalle SC, Sullivan EA, Fu Y, Turner JR. 499 Genetic Ablation of Myosin Light Chain Kinase (MLCK) Limits Epithelial Barrier Dysfunction and Attenuates Experimental Inflammatory Bowel Disease (IBD) Gastroenterology. 136: A-81. DOI: 10.1016/S0016-5085(09)60365-6 |
0.79 |
|
2009 |
Hecht AL, Marchiando AM, Turner JR. 483 Cytoskeletal Regulation and Tight Junction Reorganization During Epithelial Wound Closure In Vivo Gastroenterology. 136: A-78. DOI: 10.1016/S0016-5085(09)60349-8 |
0.759 |
|
2009 |
Shen L, Yu D, Turner JR. 478 ZO-1 C-Terminal Domains Are Essential for Tight Junction Assembly and Maintenance Gastroenterology. 136: A-77. DOI: 10.1016/S0016-5085(09)60344-9 |
0.607 |
|
2009 |
Yu D, Marchiando AM, Shen L, Turner JR. 396 The ZO-1 Actin Binding Region (ABR) Is Required for Cytoskeletal Tight Junction Regulation Gastroenterology. 136: A-66. DOI: 10.1016/S0016-5085(09)60299-7 |
0.803 |
|
2009 |
Mykoniatis A, Shen L, Tang J, Tang X, Turner J, Matlin K, Bouyer P, Matthews J. QS490. Phorbol 12-Myristate 13-Acetate Induced Endocytosis of the NA-K-2CL Cotransporter in MDCK Cells is Mediated by a Clathrin Dependent Pathway Journal of Surgical Research. 151: 304. DOI: 10.1016/J.Jss.2008.11.805 |
0.498 |
|
2008 |
Shen L, Turner JR. Intercellular junctions: actin the PARt. Current Biology : Cb. 18: R1014-7. PMID 19000799 DOI: 10.1016/J.Cub.2008.10.010 |
0.505 |
|
2008 |
Weber CR, Nalle SC, Tretiakova M, Rubin DT, Turner JR. Claudin-1 and claudin-2 expression is elevated in inflammatory bowel disease and may contribute to early neoplastic transformation. Laboratory Investigation; a Journal of Technical Methods and Pathology. 88: 1110-20. PMID 18711353 DOI: 10.1038/Labinvest.2008.78 |
0.787 |
|
2008 |
Snoeks L, Weber CR, Turner JR, Bhattacharyya M, Wasland K, Savkovic SD. Tumor suppressor Foxo3a is involved in the regulation of lipopolysaccharide-induced interleukin-8 in intestinal HT-29 cells. Infection and Immunity. 76: 4677-85. PMID 18678662 DOI: 10.1128/Iai.00227-08 |
0.368 |
|
2008 |
Gill RK, Shen L, Turner JR, Saksena S, Alrefai WA, Pant N, Esmaili A, Dwivedi A, Ramaswamy K, Dudeja PK. Serotonin modifies cytoskeleton and brush-border membrane architecture in human intestinal epithelial cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 295: G700-8. PMID 18669621 DOI: 10.1152/Ajpgi.90362.2008 |
0.49 |
|
2008 |
Purohit V, Bode JC, Bode C, Brenner DA, Choudhry MA, Hamilton F, Kang YJ, Keshavarzian A, Rao R, Sartor RB, Swanson C, Turner JR. Alcohol, intestinal bacterial growth, intestinal permeability to endotoxin, and medical consequences: Summary of a symposium Alcohol. 42: 349-361. PMID 18504085 DOI: 10.1016/J.Alcohol.2008.03.131 |
0.319 |
|
2008 |
Shen L, Weber CR, Turner JR. The tight junction protein complex undergoes rapid and continuous molecular remodeling at steady state. The Journal of Cell Biology. 181: 683-95. PMID 18474622 DOI: 10.1083/Jcb.200711165 |
0.531 |
|
2008 |
Zaborina O, Holbrook C, Chen Y, Long J, Zaborin A, Morozova I, Fernandez H, Wang Y, Turner JR, Alverdy JC. Structure-function aspects of PstS in multi-drug-resistant Pseudomonas aeruginosa. Plos Pathogens. 4: e43. PMID 18282104 DOI: 10.1371/Journal.Ppat.0040043 |
0.37 |
|
2008 |
Gill RK, Pant N, Saksena S, Singla A, Nazir TM, Vohwinkel L, Turner JR, Goldstein J, Alrefai WA, Dudeja PK. Function, expression, and characterization of the serotonin transporter in the native human intestine. American Journal of Physiology. Gastrointestinal and Liver Physiology. 294: G254-62. PMID 17991706 DOI: 10.1152/Ajpgi.00354.2007 |
0.318 |
|
2008 |
Yu D, Turner JR. Stimulus-induced reorganization of tight junction structure: the role of membrane traffic. Biochimica Et Biophysica Acta. 1778: 709-16. PMID 17915190 DOI: 10.1016/J.Bbamem.2007.07.027 |
0.508 |
|
2008 |
Wroblewski LE, Shen L, Nagy T, Ogden SR, Allen SS, Turner JR, Peek RM. T1808 Helicobacter pylori Alters Gastric Epithelial Tight Junctions in a Myosin Light Chain Kinase-Dependent Manner Gastroenterology. 134: A-567-A-568. DOI: 10.1016/S0016-5085(08)62649-9 |
0.521 |
|
2008 |
Seth A, Guntaka S, LaRusso NF, Turner JR, Rao R(. M1741a SRC Kinase-Dependent MLCK Activation Mediates Tight Junction (TJ) Disruption By Hydrogen Peroxide and TNFα in Bile Duct Epithelium Gastroenterology. 134: A-409. DOI: 10.1016/S0016-5085(08)61912-5 |
0.326 |
|
2008 |
YU D, TURNER J. 827 Actomyosin-Dependent ZO-1 Stabilization At the Tight Junction Regulates Barrier Function Gastroenterology. 134: A-118-A-118. DOI: 10.1016/S0016-5085(08)60552-1 |
0.486 |
|
2008 |
ELIAS B, AGGARWAL S, SHEN L, TURNER J, RAO R. 826 T403/404d Mutation of Occludin Attenuates PKCη-Mediated Regulation of Epithelial Tight Junctions (TJS) Gastroenterology. 134: A-118-A-118. DOI: 10.1016/S0016-5085(08)60551-X |
0.501 |
|
2008 |
Marchiando AM, Guan Y, Hecht AL, Angus EM, Montrose MH, Turner JR, Watson AJ. 823 TNF-Induced Cell Shedding in the Small Intestine Causes Novel Reorganization of Tight Junctional Proteins Gastroenterology. 134: A-117-A-118. DOI: 10.1016/S0016-5085(08)60548-X |
0.78 |
|
2008 |
Esmaili A, Borthakur A, Nazir S, Yu D, Turner JR, Alrefai WA, Hecht G, Dudeja PK, Gill RK. 719 Mechanisms of Inhibition of Serotonin Transporter (SERT) in Response to Infection By Enteropathogenic E. coli (EPEC) Gastroenterology. 134: A-103. DOI: 10.1016/S0016-5085(08)60481-3 |
0.414 |
|
2007 |
Coyne CB, Shen L, Turner JR, Bergelson JM. Coxsackievirus entry across epithelial tight junctions requires occludin and the small GTPases Rab34 and Rab5. Cell Host & Microbe. 2: 181-92. PMID 18005733 DOI: 10.1016/J.Chom.2007.07.003 |
0.561 |
|
2007 |
Treede I, Braun A, Sparla R, Kühnel M, Giese T, Turner JR, Anes E, Kulaksiz H, Füllekrug J, Stremmel W, Griffiths G, Ehehalt R. Anti-inflammatory effects of phosphatidylcholine. The Journal of Biological Chemistry. 282: 27155-64. PMID 17636253 DOI: 10.1074/Jbc.M704408200 |
0.356 |
|
2007 |
Moyer RA, Wendt MK, Johanesen PA, Turner JR, Dwinell MB. Rho activation regulates CXCL12 chemokine stimulated actin rearrangement and restitution in model intestinal epithelia. Laboratory Investigation; a Journal of Technical Methods and Pathology. 87: 807-17. PMID 17572689 DOI: 10.1038/Labinvest.3700595 |
0.423 |
|
2007 |
Schwarz BT, Wang F, Shen L, Clayburgh DR, Su L, Wang Y, Fu YX, Turner JR. LIGHT signals directly to intestinal epithelia to cause barrier dysfunction via cytoskeletal and endocytic mechanisms. Gastroenterology. 132: 2383-94. PMID 17570213 DOI: 10.1053/J.Gastro.2007.02.052 |
0.752 |
|
2007 |
Gill RK, Borthakur A, Hodges K, Turner JR, Clayburgh DR, Saksena S, Zaheer A, Ramaswamy K, Hecht G, Dudeja PK. Mechanism underlying inhibition of intestinal apical Cl-/OH- exchange following infection with enteropathogenic E. coli Journal of Clinical Investigation. 117: 428-437. PMID 17256057 DOI: 10.1172/Jci29625 |
0.652 |
|
2007 |
Weber CR, Turner JR. Inflammatory bowel disease: is it really just another break in the wall? Gut. 56: 6-8. PMID 17172583 DOI: 10.1136/Gut.2006.104182 |
0.418 |
|
2007 |
Patel NJ, Zaborina O, Wu L, Wang Y, Wolfgeher DJ, Valuckaite V, Ciancio MJ, Kohler JE, Shevchenko O, Colgan SP, Chang EB, Turner JR, Alverdy JC. Recognition of intestinal epithelial HIF-1alpha activation by Pseudomonas aeruginosa. American Journal of Physiology. Gastrointestinal and Liver Physiology. 292: G134-42. PMID 16901993 DOI: 10.1152/Ajpgi.00276.2006 |
0.317 |
|
2007 |
Mirzapoiazova T, Sammani S, Moreno L, Dudek SM, Turner JR, Garcia JG. 52 A NOVEL MYOSIN LIGHT CHAIN KINASE INHIBITOR, PIK, PROTECTS FROM LIPOPOLYSACCHARIDE-INDUCED ACUTE LUNG INJURY. Journal of Investigative Medicine. 55: S357.1-S357. DOI: 10.1136/Jim-55-02-52 |
0.335 |
|
2007 |
Gill R, Turner J, Saksena S, Alrefai W, Annaba F, Pant N, Ramaswamy K, Dudeja P. Serotonin Modifies Actin Cytoskeleton In Human Intestinal Epithelial Cells via Involvement of PKCα The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A588 |
0.365 |
|
2007 |
Graham WV, Wang Y, Schwarz BT, Marchiando AM, Turner JR. Tumor necrosis factor (TNF) increases myosin light chain kinase isoform 1 (MLCK1) transcription and targets MLCK1 to the perijunctional actomyosin ring
in vitro
and
in vivo
. The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A587 |
0.782 |
|
2007 |
Marchiando AM, Shen L, Guan Y, Watson AJM, Montrose MH, Turner JR. Real time analysis of TNF‐induced occludin internalization within jejunal epithelia of living mice The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A585-C |
0.754 |
|
2007 |
Yu D, Shen L, Turner JR. Actomyosin‐dependent tight junction (TJ) barrier regulation: Roles of ZO‐1 and actin exchange. The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A585 |
0.622 |
|
2006 |
Turner JR. Molecular basis of epithelial barrier regulation: from basic mechanisms to clinical application. The American Journal of Pathology. 169: 1901-9. PMID 17148655 DOI: 10.2353/Ajpath.2006.060681 |
0.429 |
|
2006 |
Zhang J, Owen CR, Sanders MA, Turner JR, Basson MD. The motogenic effects of cyclic mechanical strain on intestinal epithelial monolayer wound closure are matrix dependent. Gastroenterology. 131: 1179-89. PMID 17030187 DOI: 10.1053/J.Gastro.2006.08.007 |
0.366 |
|
2006 |
Wang F, Schwarz BT, Graham WV, Wang Y, Su L, Clayburgh DR, Abraham C, Turner JR. IFN-gamma-induced TNFR2 expression is required for TNF-dependent intestinal epithelial barrier dysfunction. Gastroenterology. 131: 1153-63. PMID 17030185 DOI: 10.1053/J.Gastro.2006.08.022 |
0.766 |
|
2006 |
Clayburgh DR, Musch MW, Leitges M, Fu YX, Turner JR. Coordinated epithelial NHE3 inhibition and barrier dysfunction are required for TNF-mediated diarrhea in vivo. The Journal of Clinical Investigation. 116: 2682-94. PMID 17016558 DOI: 10.1172/Jci29218 |
0.682 |
|
2006 |
Bullen TF, Forrest S, Campbell F, Dodson AR, Hershman MJ, Pritchard DM, Turner JR, Montrose MH, Watson AJ. Characterization of epithelial cell shedding from human small intestine. Laboratory Investigation; a Journal of Technical Methods and Pathology. 86: 1052-63. PMID 16909128 DOI: 10.1038/Labinvest.3700464 |
0.376 |
|
2006 |
Yu LC, Turner JR, Buret AG. LPS/CD14 activation triggers SGLT-1-mediated glucose uptake and cell rescue in intestinal epithelial cells via early apoptotic signals upstream of caspase-3. Experimental Cell Research. 312: 3276-86. PMID 16860318 DOI: 10.1016/J.Yexcr.2006.06.023 |
0.319 |
|
2006 |
Graham WV, Wang F, Clayburgh DR, Cheng JX, Yoon B, Wang Y, Lin A, Turner JR. Tumor necrosis factor-induced long myosin light chain kinase transcription is regulated by differentiation-dependent signaling events. Characterization of the human long myosin light chain kinase promoter. The Journal of Biological Chemistry. 281: 26205-15. PMID 16835238 DOI: 10.1074/Jbc.M602164200 |
0.717 |
|
2006 |
Hu Z, Wang Y, Graham WV, Su L, Musch MW, Turner JR. MAPKAPK-2 is a critical signaling intermediate in NHE3 activation following Na+-glucose cotransport. The Journal of Biological Chemistry. 281: 24247-53. PMID 16793766 DOI: 10.1074/Jbc.M602898200 |
0.567 |
|
2006 |
Zaborina O, Kohler JE, Wang Y, Bethel C, Shevchenko O, Wu L, Turner JR, Alverdy JC. Identification of multi-drug resistant Pseudomonas aeruginosa clinical isolates that are highly disruptive to the intestinal epithelial barrier. Annals of Clinical Microbiology and Antimicrobials. 5: 14. PMID 16762075 DOI: 10.1186/1476-0711-5-14 |
0.302 |
|
2006 |
Shen L, Black ED, Witkowski ED, Lencer WI, Guerriero V, Schneeberger EE, Turner JR. Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structure. Journal of Cell Science. 119: 2095-106. PMID 16638813 DOI: 10.1242/Jcs.02915 |
0.586 |
|
2006 |
Shen L, Turner JR. Role of epithelial cells in initiation and propagation of intestinal inflammation. Eliminating the static: tight junction dynamics exposed. American Journal of Physiology. Gastrointestinal and Liver Physiology. 290: G577-82. PMID 16537969 DOI: 10.1152/Ajpgi.00439.2005 |
0.579 |
|
2006 |
Blair SA, Kane SV, Clayburgh DR, Turner JR. Epithelial myosin light chain kinase expression and activity are upregulated in inflammatory bowel disease. Laboratory Investigation; a Journal of Technical Methods and Pathology. 86: 191-201. PMID 16402035 DOI: 10.1038/Labinvest.3700373 |
0.681 |
|
2006 |
Turner JR, Clayburgh DR, Musch MW, Leitges M, Fu YX. Response to field [2] Journal of Clinical Investigation. 116: 3088-3089. DOI: 10.1172/Jci30738 |
0.649 |
|
2006 |
Hu Z, Clayburgh DR, Turner JR. Mechanisms of Ion Transport Regulation by Microfilaments Advances in Molecular and Cell Biology. 37: 285-305. DOI: 10.1016/S1569-2558(06)37013-0 |
0.638 |
|
2005 |
Clayburgh DR, Barrett TA, Tang Y, Meddings JB, Van Eldik LJ, Watterson DM, Clarke LL, Mrsny RJ, Turner JR. Epithelial myosin light chain kinase-dependent barrier dysfunction mediates T cell activation-induced diarrhea in vivo. The Journal of Clinical Investigation. 115: 2702-15. PMID 16184195 DOI: 10.1172/Jci24970 |
0.719 |
|
2005 |
Wu LR, Zaborina O, Zaborin A, Chang EB, Musch M, Holbrook C, Turner JR, Alverdy JC. Surgical injury and metabolic stress enhance the virulence of the human opportunistic pathogen Pseudomonas aeruginosa. Surgical Infections. 6: 185-95. PMID 16128625 DOI: 10.1089/Sur.2005.6.185 |
0.327 |
|
2005 |
Shifflett DE, Clayburgh DR, Koutsouris A, Turner JR, Hecht GA. Enteropathogenic E. coli disrupts tight junction barrier function and structure in vivo. Laboratory Investigation; a Journal of Technical Methods and Pathology. 85: 1308-24. PMID 16127426 DOI: 10.1038/Labinvest.3700330 |
0.664 |
|
2005 |
Utech M, Ivanov AI, Samarin SN, Bruewer M, Turner JR, Mrsny RJ, Parkos CA, Nusrat A. Mechanism of IFN-gamma-induced endocytosis of tight junction proteins: myosin II-dependent vacuolarization of the apical plasma membrane. Molecular Biology of the Cell. 16: 5040-52. PMID 16055505 DOI: 10.1091/Mbc.E05-03-0193 |
0.36 |
|
2005 |
Wu L, Estrada O, Zaborina O, Bains M, Shen L, Kohler JE, Patel N, Musch MW, Chang EB, Fu YX, Jacobs MA, Nishimura MI, Hancock RE, Turner JR, Alverdy JC. Recognition of host immune activation by Pseudomonas aeruginosa. Science (New York, N.Y.). 309: 774-7. PMID 16051797 DOI: 10.1126/Science.1112422 |
0.503 |
|
2005 |
Kimura Y, Turner JR, Braasch DA, Buddington RK. Lumenal adenosine and AMP rapidly increase glucose transport by intact small intestine. American Journal of Physiology. Gastrointestinal and Liver Physiology. 289: G1007-14. PMID 16020657 DOI: 10.1152/Ajpgi.00085.2005 |
0.345 |
|
2005 |
Shen L, Turner JR. Actin depolymerization disrupts tight junctions via caveolae-mediated endocytosis. Molecular Biology of the Cell. 16: 3919-36. PMID 15958494 DOI: 10.1091/Mbc.E04-12-1089 |
0.565 |
|
2005 |
Wang J, Anders RA, Wang Y, Turner JR, Abraham C, Pfeffer K, Fu YX. The critical role of LIGHT in promoting intestinal inflammation and Crohn's disease. Journal of Immunology (Baltimore, Md. : 1950). 174: 8173-82. PMID 15944326 DOI: 10.4049/Jimmunol.174.12.8173 |
0.374 |
|
2005 |
Owens SE, Graham WV, Siccardi D, Turner JR, Mrsny RJ. A strategy to identify stable membrane-permeant peptide inhibitors of myosin light chain kinase. Pharmaceutical Research. 22: 703-9. PMID 15906163 DOI: 10.1007/S11095-005-2584-9 |
0.601 |
|
2005 |
Russo JM, Florian P, Shen L, Graham WV, Tretiakova MS, Gitter AH, Mrsny RJ, Turner JR. Distinct temporal-spatial roles for rho kinase and myosin light chain kinase in epithelial purse-string wound closure. Gastroenterology. 128: 987-1001. PMID 15825080 DOI: 10.1053/J.Gastro.2005.01.004 |
0.665 |
|
2005 |
Gill RK, Saksena S, Tyagi S, Alrefai WA, Malakooti J, Sarwar Z, Turner JR, Ramaswamy K, Dudeja PK. Serotonin inhibits Na+/H+ exchange activity via 5-HT4 receptors and activation of PKC alpha in human intestinal epithelial cells. Gastroenterology. 128: 962-74. PMID 15825078 DOI: 10.1053/J.Gastro.2005.02.011 |
0.306 |
|
2005 |
Wang F, Graham WV, Wang Y, Witkowski ED, Schwarz BT, Turner JR. Interferon-gamma and tumor necrosis factor-alpha synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression. The American Journal of Pathology. 166: 409-19. PMID 15681825 DOI: 10.1016/S0002-9440(10)62264-X |
0.59 |
|
2005 |
Savkovic SD, Villanueva J, Turner JR, Matkowskyj KA, Hecht G. Mouse model of enteropathogenic Escherichia coli infection. Infection and Immunity. 73: 1161-70. PMID 15664959 DOI: 10.1128/Iai.73.2.1161-1170.2005 |
0.326 |
|
2005 |
Siccardi D, Turner JR, Mrsny RJ. Regulation of intestinal epithelial function: a link between opportunities for macromolecular drug delivery and inflammatory bowel disease. Advanced Drug Delivery Reviews. 57: 219-35. PMID 15555739 DOI: 10.1016/J.Addr.2004.08.005 |
0.381 |
|
2005 |
Kohler JE, Zaborina O, Wu L, Wang Y, Bethel C, Chen Y, Shapiro J, Turner JR, Alverdy JC. Components of intestinal epithelial hypoxia activate the virulence circuitry of Pseudomonas. American Journal of Physiology. Gastrointestinal and Liver Physiology. 288: G1048-54. PMID 15550562 DOI: 10.1152/Ajpgi.00241.2004 |
0.333 |
|
2005 |
Shiue H, Musch MW, Wang Y, Chang EB, Turner JR. Akt2 phosphorylates ezrin to trigger NHE3 translocation and activation. The Journal of Biological Chemistry. 280: 1688-95. PMID 15531580 DOI: 10.1074/Jbc.M409471200 |
0.326 |
|
2005 |
Arvans DL, Vavricka SR, Ren H, Musch MW, Kang L, Rocha FG, Lucioni A, Turner JR, Alverdy J, Chang EB. Luminal bacterial flora determines physiological expression of intestinal epithelial cytoprotective heat shock proteins 25 and 72. American Journal of Physiology. Gastrointestinal and Liver Physiology. 288: G696-704. PMID 15528251 DOI: 10.1152/Ajpgi.00206.2004 |
0.331 |
|
2004 |
Clayburgh DR, Rosen S, Witkowski ED, Wang F, Blair S, Dudek S, Garcia JG, Alverdy JC, Turner JR. A differentiation-dependent splice variant of myosin light chain kinase, MLCK1, regulates epithelial tight junction permeability. The Journal of Biological Chemistry. 279: 55506-13. PMID 15507455 DOI: 10.1074/Jbc.M408822200 |
0.693 |
|
2004 |
Tomson FL, Koutsouris A, Viswanathan VK, Turner JR, Savkovic SD, Hecht G. Differing roles of protein kinase C-zeta in disruption of tight junction barrier by enteropathogenic and enterohemorrhagic Escherichia coli. Gastroenterology. 127: 859-69. PMID 15362041 DOI: 10.1053/J.Gastro.2004.06.014 |
0.319 |
|
2004 |
Zhao H, Shiue H, Palkon S, Wang Y, Cullinan P, Burkhardt JK, Musch MW, Chang EB, Turner JR. Ezrin regulates NHE3 translocation and activation after Na+-glucose cotransport. Proceedings of the National Academy of Sciences of the United States of America. 101: 9485-90. PMID 15197272 DOI: 10.1073/Pnas.0308400101 |
0.33 |
|
2004 |
Wang J, Anders RA, Wu Q, Peng D, Cho JH, Sun Y, Karaliukas R, Kang HS, Turner JR, Fu YX. Dysregulated LIGHT expression on T cells mediates intestinal inflammation and contributes to IgA nephropathy. The Journal of Clinical Investigation. 113: 826-35. PMID 15067315 DOI: 10.1172/Jci20096 |
0.404 |
|
2004 |
Clayburgh DR, Shen L, Turner JR. A porous defense: the leaky epithelial barrier in intestinal disease. Laboratory Investigation; a Journal of Technical Methods and Pathology. 84: 282-91. PMID 14767487 DOI: 10.1038/Labinvest.3700050 |
0.746 |
|
2004 |
Wu L, Zaborina O, Zaborin A, Chang EB, Musch M, Holbrook C, Shapiro J, Turner JR, Wu G, Lee KY, Alverdy JC. High-molecular-weight polyethylene glycol prevents lethal sepsis due to intestinal Pseudomonas aeruginosa. Gastroenterology. 126: 488-98. PMID 14762786 DOI: 10.1053/J.Gastro.2003.11.011 |
0.364 |
|
2003 |
Lahav M, Musch MW, Ren H, Turner JR, Chang EB. Downregulation of cytoprotective intestinal heat shock proteins in inflamed mucosa and by inflammatory cytokines Gastroenterology. 124: A497. DOI: 10.1016/S0016-5085(03)82514-3 |
0.357 |
|
2003 |
Arvans DL, Ren H, Kang LH, Turner JR, Alverdy J, Chang EB. Luminal bacterial flora determine physiological expression of intestinal epithelial cytoprotective heat shock protein 25 and 72 expression Gastroenterology. 124: A484. DOI: 10.1016/S0016-5085(03)82451-4 |
0.319 |
|
2003 |
Shen L, Mrsny RJ, Turner JR. Real-time imaging of occludin and actin in live cells reveals early events associated with loss of tight junction barrier properties Gastroenterology. 124: A88. DOI: 10.1016/S0016-5085(03)80433-X |
0.507 |
|
2003 |
Clayburgh DR, Rosen S, Palkon S, Alverdy JA, Turner JR. Myosin light chain kinase isoform expression is regulated during crypt-villus maturation Gastroenterology. 124: A87. DOI: 10.1016/S0016-5085(03)80429-8 |
0.644 |
|
2002 |
Abner SR, Hill DE, Turner JR, Black ED, Bartlett P, Urban JF, Mansfield LS. Response of intestinal epithelial cells to Trichuris suis excretory-secretory products and the influence on Campylobacter jejuni invasion under in vitro conditions. The Journal of Parasitology. 88: 738-45. PMID 12197123 DOI: 10.1645/0022-3395(2002)088[0738:Roiect]2.0.Co;2 |
0.329 |
|
2002 |
Zolotarevsky Y, Hecht G, Koutsouris A, Gonzalez DE, Quan C, Tom J, Mrsny RJ, Turner JR. A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease. Gastroenterology. 123: 163-72. PMID 12105845 DOI: 10.1053/Gast.2002.34235 |
0.387 |
|
2002 |
Edens HA, Levi BP, Jaye DL, Walsh S, Reaves TA, Turner JR, Nusrat A, Parkos CA. Neutrophil transepithelial migration: evidence for sequential, contact-dependent signaling events and enhanced paracellular permeability independent of transjunctional migration. Journal of Immunology (Baltimore, Md. : 1950). 169: 476-86. PMID 12077279 DOI: 10.4049/Jimmunol.169.1.476 |
0.428 |
|
2002 |
Kles K, Turner J, Tappenden K. Enteral nutrients alter enterocyte function within an in vitro model similar to an acute in vivo rat model during hypoxia Journal of Parenteral and Enteral Nutrition. 26: 71-76. PMID 11871739 DOI: 10.1177/014860710202600271 |
0.307 |
|
2001 |
Berglund JJ, Riegler M, Zolotarevsky Y, Wenzl E, Turner JR. Regulation of human jejunal transmucosal resistance and MLC phosphorylation by Na(+)-glucose cotransport. American Journal of Physiology. Gastrointestinal and Liver Physiology. 281: G1487-93. PMID 11705754 DOI: 10.1152/Ajpgi.2001.281.6.G1487 |
0.357 |
|
2001 |
Turner JR, Black ED. NHE3-dependent cytoplasmic alkalinization is triggered by Na+-glucose cotransport in intestinal epithelia American Journal of Physiology - Cell Physiology. 281: C1533-C1541. PMID 11600416 DOI: 10.1152/Ajpcell.2001.281.5.C1533 |
0.305 |
|
2001 |
Furuta GT, Turner JR, Taylor CT, Hershberg RM, Comerford K, Narravula S, Podolsky DK, Colgan SP. Hypoxia-inducible factor 1-dependent induction of intestinal trefoil factor protects barrier function during hypoxia Journal of Experimental Medicine. 193: 1027-1034. PMID 11342587 DOI: 10.1084/Jem.193.9.1027 |
0.403 |
|
2001 |
Yu Y, Rishi AK, Turner JR, Liu D, Black ED, Moshier JA, Majumdar APN. Cloning of a novel EGFR-related peptide: A putative negative regulator of EGFR American Journal of Physiology - Cell Physiology. 280: C1083-C1089. PMID 11287320 DOI: 10.1152/Ajpcell.2001.280.5.C1083 |
0.31 |
|
2001 |
Black ED, Guerriero V, Turner JR. Increases in perijunctional actomyosin ring area and tight junction permeability parallel myosin light chain phosphorylation following expression of the myosin light chain kinase catalytic domain Gastroenterology. 120: A110. DOI: 10.1016/S0016-5085(08)80538-0 |
0.316 |
|
2000 |
Turner JR, Black ED, Ward J, Tse CM, Uchwat FA, Alli HA, Donowitz M, Madara JL, Angle JM. Transepithelial resistance can be regulated by the intestinal brush-border Na(+)/H(+) exchanger NHE3. American Journal of Physiology. Cell Physiology. 279: C1918-24. PMID 11078707 DOI: 10.1152/Ajpcell.2000.279.6.C1918 |
0.307 |
|
2000 |
Nusrat A, Turner JR, Madara JL. Molecular physiology and pathophysiology of tight junctions. IV. Regulation of tight junctions by extracellular stimuli: nutrients, cytokines, and immune cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 279: G851-7. PMID 11052980 DOI: 10.1152/Ajpgi.2000.279.5.G851 |
0.411 |
|
2000 |
Turner JR. 'Putting the squeeze' on the tight junction: Understanding cytoskeletal regulation Seminars in Cell and Developmental Biology. 11: 301-308. PMID 10966864 DOI: 10.1006/Scdb.2000.0180 |
0.36 |
|
2000 |
Turner JR. Show me the pathway! Regulation of paracellular permeability by Na+- glucose cotransport Advanced Drug Delivery Reviews. 41: 265-281. PMID 10854686 DOI: 10.1016/S0169-409X(00)00046-6 |
0.387 |
|
2000 |
Furuta GT, Turner JR, Black ED, Podolsky DK, Colgan SP. Intestinal epithelial barrier function is uniquely resistant to changes elicited by hypoxia; critical role for hypoxia inducible factor-1 (HIF-1)-dependent induction of intestinal trefoil factor (ITF) Gastroenterology. 118: A671. DOI: 10.1016/S0016-5085(00)84820-9 |
0.348 |
|
2000 |
Turner JR, Black ED, Guerriero V, Haelewyn K. Regulated expression of the myosin light chain kinase catalytic domain increases paracellular permeability and alters tight junction structure Gastroenterology. 118: A432-A433. DOI: 10.1016/S0016-5085(00)83843-3 |
0.343 |
|
1999 |
Turner JR, Angle JM, Black ED, Joyal JL, Sacks DB, Madara JL. PKC-dependent regulation of transepithelial resistance: roles of MLC and MLC kinase. The American Journal of Physiology. 277: C554-62. PMID 10484342 DOI: 10.1152/Ajpcell.1999.277.3.C554 |
0.315 |
|
1999 |
Saubermann LJ, Probert CS, Christ AD, Chott A, Turner JR, Stevens AC, Balk SP, Blumberg RS. Evidence of T cell receptor beta-chain patterns in inflammatory and noninflammatory bowel disease states. The American Journal of Physiology. 276: G613-21. PMID 10070037 DOI: 10.1152/Ajpgi.1999.276.3.G613 |
0.338 |
|
1998 |
Turner J, Black E, Angle J, Alli H, Madara J. Inhibition of intestinal epithelial Na+-H+ exchange results in increased transepithelial resistance and decreased myosin light chain phosphorylation Gastroenterology. 114: A425. DOI: 10.1016/S0016-5085(98)81723-X |
0.346 |
|
1998 |
Angle J, Joyal J, Black E, Alli H, Sacks D, Madara J, Turner J. Protein kinase c-mediated phosphorylation of myosin light chain kinase (MLCK) inhibits myosin light chain (MLC) phosphorylation and results in increased transepithelial resistance (TER) Gastroenterology. 114: A348. DOI: 10.1016/S0016-5085(98)81411-X |
0.318 |
|
1997 |
Turner JR, Rill BK, Carlson SL, Carnes D, Kerner R, Mrsny RJ, Madara JL. Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylation. American Journal of Physiology. Cell Physiology. 273: C1378-C1385. PMID 29584994 DOI: 10.1152/ajpcell.1997.273.4.C1378 |
0.311 |
|
1997 |
Turner JR, Rill BK, Carlson SL, Carnes D, Kerner R, Mrsny RJ, Madara JL. Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylation. The American Journal of Physiology. 273: C1378-85. PMID 9357784 DOI: 10.1152/Ajpcell.1997.273.4.C1378 |
0.428 |
|
1997 |
Aster JC, Robertson ES, Hasserjian RP, Turner JR, Kieff E, Sklar J. Oncogenic forms of NOTCH1 lacking either the primary binding site for RBP-Jκ or nuclear localization sequences retain the ability to associate with RBP-Jκ and activate transcription Journal of Biological Chemistry. 272: 11336-11343. PMID 9111040 DOI: 10.1074/Jbc.272.17.11336 |
0.307 |
|
1996 |
Turner JR, Lencer WI, Carlson S, Madara JL. Carboxy-terminal vesicular stomatitis virus G protein-tagged intestinal Na+-dependent glucose cotransporter (SGLT1): maintenance of surface expression and global transport function with selective perturbation of transport kinetics and polarized expression. The Journal of Biological Chemistry. 271: 7738-44. PMID 8631815 DOI: 10.1074/Jbc.271.13.7738 |
0.359 |
|
1995 |
Turner JR, Madara JL. Physiological regulation of intestinal epithelial tight junctions as a consequence of Na(+)-coupled nutrient transport. Gastroenterology. 109: 1391-6. PMID 7557112 DOI: 10.1016/0016-5085(95)90605-3 |
0.346 |
|
1995 |
Nusrat A, Giry M, Turner JR, Colgan SP, Parkos CA, Carnes D, Lemichez E, Boquet P, Madara JL. Rho protein regulates tight junctions and perijunctional actin organization in polarized epithelia. Proceedings of the National Academy of Sciences of the United States of America. 92: 10629-33. PMID 7479854 DOI: 10.1073/Pnas.92.23.10629 |
0.37 |
|
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