Stuart J. Frank - Publications

Affiliations: 
Cell Biology University of Alabama, Birmingham, Birmingham, AL, United States 
Area:
Cell Biology

129 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Sonkar R, Berry R, Latimer MN, Prabhu SD, Young ME, Frank SJ. Augmented Cardiac Growth Hormone Signaling Contributes to Cardiomyopathy Following Genetic Disruption of the Cardiomyocyte Circadian Clock. Frontiers in Pharmacology. 13: 836725. PMID 35250583 DOI: 10.3389/fphar.2022.836725  0.353
2020 Frank SJ. Classical and novel GH receptor signaling pathways. Molecular and Cellular Endocrinology. 110999. PMID 32835785 DOI: 10.1016/J.Mce.2020.110999  0.553
2020 Ren G, Kim T, Kim HS, Young ME, Muccio DD, Atigadda VR, Blum SI, Tse HM, Habegger KM, Bhatnagar S, Coric T, Bjornsti MA, Shalev A, Frank SJ, Kim JA. A Small Molecule, UAB126, Reverses Diet-Induced Obesity and its Associated Metabolic Disorders. Diabetes. PMID 32611548 DOI: 10.2337/Db19-1001  0.368
2020 Mia S, Kane MS, Latimer MN, Reitz CJ, Sonkar R, Benavides GA, Smith SR, Frank SJ, Martino TA, Zhang J, Darley-Usmar V, Young ME. Differential Effects of REV-ERBa/b Agonism on Cardiac Gene Expression, Metabolism, and Contractile Function in a Mouse Model of Circadian Disruption. American Journal of Physiology. Heart and Circulatory Physiology. PMID 32357113 DOI: 10.1152/Ajpheart.00709.2019  0.303
2020 DiToro D, Harbour SN, Bando JK, Benavides G, Witte S, Laufer VA, Moseley C, Singer JR, Frey B, Turner H, Bruning J, Darley-Usmar V, Gao M, Conover C, Hatton RD, ... Frank S, et al. Insulin-Like Growth Factors Are Key Regulators of T Helper 17 Regulatory T Cell Balance in Autoimmunity. Immunity. 52: 650-667.e10. PMID 32294406 DOI: 10.1016/J.Immuni.2020.03.013  0.422
2020 Buckels A, Zhang Y, Jiang J, Athar M, Afaq F, Shevde-Samant L, Frank SJ. Autocrine/paracrine actions of growth hormone in human melanoma cell lines. Biochemistry and Biophysics Reports. 21: 100716. PMID 31890904 DOI: 10.1016/J.Bbrep.2019.100716  0.477
2020 Chen C, Jiang J, Rao TC, Frank SJ, Leier A. Revealing the Mechanistic Details of Growth Hormone Receptor and Prolactin Receptor Interactions on the Cell Membrane Biophysical Journal. 118: 94a-95a. DOI: 10.1016/j.bpj.2019.11.679  0.355
2019 Zhang Y, Gc S, Patel SB, Liu Y, Paterson AJ, Kappes JC, Jiang J, Frank SJ. Growth hormone (GH) receptor (GHR)-specific inhibition of GH-Induced signaling by soluble IGF-1 receptor (sol IGF-1R). Molecular and Cellular Endocrinology. PMID 31100495 DOI: 10.1016/J.Mce.2019.05.004  0.522
2018 Berry R, McGinnis GR, Banerjee RR, Young ME, Frank SJ. Differential tissue response to growth hormone in mice. Febs Open Bio. 8: 1146-1154. PMID 29988606 DOI: 10.1002/2211-5463.12444  0.413
2018 Fang Y, Hill CM, Darcy J, Reyes-Ordoñez A, Arauz E, McFadden S, Zhang C, Osland J, Gao J, Zhang T, Frank SJ, Javors MA, Yuan R, Kopchick JJ, Sun LY, et al. Effects of rapamycin on growth hormone receptor knockout mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 29378959 DOI: 10.1073/Pnas.1717065115  0.435
2017 Liu Y, Jiang J, Lepik B, Zhang Y, Zinn KR, Frank SJ. Subdomain 2, Not the Transmembrane Domain, Determines the Dimerization Partner of Growth Hormone Receptor and Prolactin Receptor. Endocrinology. 158: 3235-3248. PMID 28977606 DOI: 10.1210/En.2017-00469  0.493
2017 McGinnis GR, Tang Y, Brewer RA, Brahma MK, Stanley HL, Shanmugam G, Rajasekaran NS, Rowe GC, Frank SJ, Wende AR, Dale Abel E, Taegtmeyer H, Litovsky S, Darley-Usmar V, Zhang J, et al. Genetic disruption of the cardiomyocyte circadian clock differentially influences insulin-mediated processes in the heart. Journal of Molecular and Cellular Cardiology. PMID 28736261 DOI: 10.1016/J.Yjmcc.2017.07.005  0.356
2017 Sawada T, Arai D, Jing X, Miyajima M, Frank SJ, Sakaguchi K. Molecular interactions of EphA4, growth hormone receptor, Janus kinase 2, and signal transducer and activator of transcription 5B. Plos One. 12: e0180785. PMID 28686668 DOI: 10.1371/Journal.Pone.0180785  0.566
2017 Hjortebjerg R, Berryman DE, Comisford R, Frank SJ, List EO, Bjerre M, Frystyk J, Kopchick JJ. Insulin, IGF-1, and GH Receptors are Altered in an Adipose Tissue Depot-Specific Manner in Male Mice with Modified GH Action. Endocrinology. PMID 28323915 DOI: 10.1210/En.2017-00084  0.411
2016 Zhang Y, Wang X, Loesch K, May LA, Davis GE, Jiang J, Frank SJ. Tissue Inhibitor of Metalloproteinases 3 (TIMP3) Modulates Growth Hormone Receptor (GHR) Susceptibility to Inducible Proteolysis and Cellular Growth Hormone (GH) Sensitivity. Molecular Endocrinology (Baltimore, Md.). me20151302. PMID 27075707 DOI: 10.1210/Me.2015-1302  0.824
2016 Liu Y, Zhang Y, Jiang J, Lobie PE, Paulmurugan R, Langenheim JF, Chen WY, Zinn KR, Frank SJ. GHR/PRLR Hetero-multimer is Composed of GHR Homodimers and PRLR Homodimers. Molecular Endocrinology (Baltimore, Md.). me20151319. PMID 27003442 DOI: 10.1210/Me.2015-1319  0.547
2015 Chen H, Kleinberger JW, Takane KK, Salim F, Fiaschi-Taesch N, Pappas K, Parsons R, Jiang J, Zhang Y, Liu H, Wang P, Bender AS, Frank SJ, Stewart AF. Augmented Stat5 Signaling Bypasses Multiple Impediments to Lactogen-Mediated Proliferation in Human Beta Cells. Diabetes. PMID 26159175 DOI: 10.2337/Db15-0083  0.393
2015 Cordoba-Chacon J, Majumdar N, List EO, Diaz-Ruiz A, Frank SJ, Manzano A, Bartrons R, Puchowicz M, Kopchick JJ, Kineman RD. Growth hormone inhibits hepatic de novo lipogenesis in adult mice. Diabetes. PMID 26015548 DOI: 10.2337/Db15-0370  0.404
2014 Gan Y, Buckels A, Liu Y, Zhang Y, Paterson AJ, Jiang J, Zinn KR, Frank SJ. Human GH receptor-IGF-1 receptor interaction: implications for GH signaling. Molecular Endocrinology (Baltimore, Md.). 28: 1841-54. PMID 25211187 DOI: 10.1210/Me.2014-1174  0.671
2014 Liu Y, Berry PA, Zhang Y, Jiang J, Lobie PE, Paulmurugan R, Langenheim JF, Chen WY, Zinn KR, Frank SJ. Dynamic analysis of GH receptor conformational changes by split luciferase complementation. Molecular Endocrinology (Baltimore, Md.). 28: 1807-19. PMID 25188449 DOI: 10.1210/Me.2014-1153  0.526
2014 Zhao Y, Xiao X, Frank SJ, Lin HY, Xia Y. Distinct mechanisms of induction of hepatic growth hormone resistance by endogenous IL-6, TNF-α, and IL-1β. American Journal of Physiology. Endocrinology and Metabolism. 307: E186-98. PMID 24895283 DOI: 10.1152/Ajpendo.00652.2013  0.317
2014 Gan Y, Paterson AJ, Zhang Y, Jiang J, Frank SJ. Functional collaboration of insulin-like growth factor-1 receptor (IGF-1R), but not insulin receptor (IR), with acute GH signaling in mouse calvarial cells. Endocrinology. 155: 1000-9. PMID 24302626 DOI: 10.1210/En.2013-1732  0.64
2013 Gan Y, Zhang Y, Buckels A, Paterson AJ, Jiang J, Clemens TL, Zhang ZY, Du K, Chang Y, Frank SJ. IGF-1R modulation of acute GH-induced STAT5 signaling: role of protein tyrosine phosphatase activity. Molecular Endocrinology (Baltimore, Md.). 27: 1969-79. PMID 24030252 DOI: 10.1210/Me.2013-1178  0.648
2013 Zhang Y, Liu Y, Li X, Gao W, Zhang W, Guan Q, Jiang J, Frank SJ, Wang X. Effects of insulin and IGF-I on growth hormone- induced STAT5 activation in 3T3-F442A adipocytes. Lipids in Health and Disease. 12: 56. PMID 23631823 DOI: 10.1186/1476-511X-12-56  0.459
2013 Corrick RM, Li L, Frank SJ, Messina JL. Hepatic growth hormone resistance after acute injury. Endocrinology. 154: 1577-88. PMID 23417424 DOI: 10.1210/En.2012-2134  0.392
2013 List EO, Berryman DE, Funk K, Gosney ES, Jara A, Kelder B, Wang X, Kutz L, Troike K, Lozier N, Mikula V, Lubbers ER, Zhang H, Vesel C, Junnila RK, ... Frank SJ, et al. The role of GH in adipose tissue: lessons from adipose-specific GH receptor gene-disrupted mice. Molecular Endocrinology (Baltimore, Md.). 27: 524-35. PMID 23349524 DOI: 10.1210/Me.2012-1330  0.354
2013 Xu J, Sun D, Jiang J, Deng L, Zhang Y, Yu H, Bahl D, Langenheim JF, Chen WY, Fuchs SY, Frank SJ. The role of prolactin receptor in GH signaling in breast cancer cells. Molecular Endocrinology (Baltimore, Md.). 27: 266-79. PMID 23192981 DOI: 10.1210/Me.2012-1297  0.696
2012 Deng L, Jiang J, Frank SJ. Growth hormone-induced JAK2 signaling and GH receptor down-regulation: role of GH receptor intracellular domain tyrosine residues. Endocrinology. 153: 2311-22. PMID 22416081 DOI: 10.1210/En.2011-1452  0.72
2012 D'Mello S, Trauernicht A, Ryan A, Bonkowski E, Willson T, Trapnell BC, Frank SJ, Kugasathan S, Denson LA. Innate dysfunction promotes linear growth failure in pediatric Crohn's disease and growth hormone resistance in murine ileitis. Inflammatory Bowel Diseases. 18: 236-45. PMID 21337672 DOI: 10.1002/Ibd.21689  0.355
2011 Ma F, Wei Z, Shi C, Gan Y, Lu J, Frank SJ, Balducci J, Huang Y. Signaling cross talk between growth hormone (GH) and insulin-like growth factor-I (IGF-I) in pancreatic islet β-cells. Molecular Endocrinology (Baltimore, Md.). 25: 2119-33. PMID 22034225 DOI: 10.1210/Me.2011-1052  0.682
2011 Jiang J, Wan Y, Wang X, Xu J, Harris JM, Lobie PE, Zhang Y, Zinn KR, Waters MJ, Frank SJ. Inhibitory GH receptor extracellular domain monoclonal antibodies: three-dimensional epitope mapping. Endocrinology. 152: 4777-88. PMID 21990310 DOI: 10.1210/En.2011-1336  0.426
2011 Zheng Y, Qin H, Frank SJ, Deng L, Litchfield DW, Tefferi A, Pardanani A, Lin FT, Li J, Sha B, Benveniste EN. A CK2-dependent mechanism for activation of the JAK-STAT signaling pathway. Blood. 118: 156-66. PMID 21527517 DOI: 10.1182/Blood-2010-01-266320  0.662
2011 Wang X, Cowan JW, Gerhart M, Zelickson BR, Jiang J, He K, Wolfe MS, Black RA, Frank SJ. γ-Secretase-mediated growth hormone receptor proteolysis: mapping of the intramembranous cleavage site. Biochemical and Biophysical Research Communications. 408: 432-6. PMID 21514282 DOI: 10.1016/J.Bbrc.2011.04.041  0.756
2011 Xu J, Zhang Y, Berry PA, Jiang J, Lobie PE, Langenheim JF, Chen WY, Frank SJ. Growth hormone signaling in human T47D breast cancer cells: potential role for a growth hormone receptor-prolactin receptor complex. Molecular Endocrinology (Baltimore, Md.). 25: 597-610. PMID 21310852 DOI: 10.1210/Jcem.96.3.Zeg872  0.562
2011 Li X, Huang Y, Jiang J, Frank SJ. Synergy in ERK activation by cytokine receptors and tyrosine kinase growth factor receptors. Cellular Signalling. 23: 417-24. PMID 20946955 DOI: 10.1016/J.Cellsig.2010.10.016  0.582
2010 Mavalli MD, DiGirolamo DJ, Fan Y, Riddle RC, Campbell KS, van Groen T, Frank SJ, Sperling MA, Esser KA, Bamman MM, Clemens TL. Distinct growth hormone receptor signaling modes regulate skeletal muscle development and insulin sensitivity in mice. The Journal of Clinical Investigation. 120: 4007-20. PMID 20921627 DOI: 10.1172/Jci42447  0.435
2010 Gan Y, Zhang Y, Digirolamo DJ, Jiang J, Wang X, Cao X, Zinn KR, Carbone DP, Clemens TL, Frank SJ. Deletion of IGF-I receptor (IGF-IR) in primary osteoblasts reduces GH-induced STAT5 signaling. Molecular Endocrinology (Baltimore, Md.). 24: 644-56. PMID 20133448 DOI: 10.1210/Me.2009-0357  0.707
2010 Houghton AM, Rzymkiewicz DM, Ji H, Gregory AD, Egea EE, Metz HE, Stolz DB, Land SR, Marconcini LA, Kliment CR, Jenkins KM, Beaulieu KA, Mouded M, Frank SJ, Wong KK, et al. Neutrophil elastase-mediated degradation of IRS-1 accelerates lung tumor growth. Nature Medicine. 16: 219-23. PMID 20081861 DOI: 10.1038/Nm.2084  0.348
2010 Yang N, Jiang J, Deng L, Waters MJ, Wang X, Frank SJ. Growth hormone receptor targeting to lipid rafts requires extracellular subdomain 2. Biochemical and Biophysical Research Communications. 391: 414-8. PMID 19914217 DOI: 10.1016/J.Bbrc.2009.11.072  0.696
2009 Aalbers AM, Chin D, Pratt KL, Little BM, Frank SJ, Hwa V, Rosenfeld RG. Extreme elevation of serum growth hormone-binding protein concentrations resulting from a novel heterozygous splice site mutation of the growth hormone receptor gene. Hormone Research. 71: 276-84. PMID 19339792 DOI: 10.1159/000208801  0.457
2009 Wang X, Yang N, Deng L, Li X, Jiang J, Gan Y, Frank SJ. Interruption of growth hormone signaling via SHC and ERK in 3T3-F442A preadipocytes upon knockdown of insulin receptor substrate-1. Molecular Endocrinology (Baltimore, Md.). 23: 486-96. PMID 19164446 DOI: 10.1210/Me.2008-0407  0.784
2009 DiGirolamo DJ, Mukherjee A, Fulzele K, Gan Y, Cao X, Frank SJ, Clemens TL. Mode of growth hormone action in osteoblasts. VOLUME 282 (2007) PAGES 31666-31674 Journal of Biological Chemistry. 284: 10992-10992. DOI: 10.1074/Jbc.A705219200  0.511
2008 Li X, Huang Y, Jiang J, Frank SJ. ERK-dependent threonine phosphorylation of EGF receptor modulates receptor downregulation and signaling. Cellular Signalling. 20: 2145-55. PMID 18762250 DOI: 10.1016/J.Cellsig.2008.08.006  0.46
2008 Frank SJ, Fuchs SY. Modulation of growth hormone receptor abundance and function: roles for the ubiquitin-proteasome system. Biochimica Et Biophysica Acta. 1782: 785-94. PMID 18586085 DOI: 10.1016/J.Bbadis.2008.06.001  0.531
2008 Wang X, Jiang J, Warram J, Baumann G, Gan Y, Menon RK, Denson LA, Zinn KR, Frank SJ. Endotoxin-induced proteolytic reduction in hepatic growth hormone (GH) receptor: a novel mechanism for GH insensitivity. Molecular Endocrinology (Baltimore, Md.). 22: 1427-37. PMID 18323468 DOI: 10.1210/Me.2007-0561  0.681
2008 Swaminathan G, Varghese B, Thangavel C, Carbone CJ, Plotnikov A, Kumar KG, Jablonski EM, Clevenger CV, Goffin V, Deng L, Frank SJ, Fuchs SY. Prolactin stimulates ubiquitination, initial internalization, and degradation of its receptor via catalytic activation of Janus kinase 2. The Journal of Endocrinology. 196: R1-7. PMID 18252943 DOI: 10.1677/Joe-07-0554  0.687
2008 Frank SJ. Mechanistic aspects of crosstalk between GH and PRL and ErbB receptor family signaling. Journal of Mammary Gland Biology and Neoplasia. 13: 119-29. PMID 18236142 DOI: 10.1007/S10911-008-9065-9  0.519
2008 Yang N, Langenheim JF, Wang X, Jiang J, Chen WY, Frank SJ. Activation of growth hormone receptors by growth hormone and growth hormone antagonist dimers: insights into receptor triggering. Molecular Endocrinology (Baltimore, Md.). 22: 978-88. PMID 18096690 DOI: 10.1210/Me.2007-0424  0.627
2007 Rhoads RP, Kim JW, Van Amburgh ME, Ehrhardt RA, Frank SJ, Boisclair YR. Effect of nutrition on the GH responsiveness of liver and adipose tissue in dairy cows Journal of Endocrinology. 195: 49-58. PMID 17911396 DOI: 10.1677/Joe-07-0068  0.362
2007 Srinivasan B, Wang Z, Brun-Zinkernagel AM, Collier RJ, Black RA, Frank SJ, Barker PA, Roque RS. Photic injury promotes cleavage of p75NTR by TACE and nuclear trafficking of the p75 intracellular domain. Molecular and Cellular Neurosciences. 36: 449-61. PMID 17904861 DOI: 10.1016/J.Mcn.2007.08.005  0.398
2007 Loesch K, Deng L, Wang X, He K, Jiang J, Frank SJ. Endoplasmic reticulum-associated degradation of growth hormone receptor in Janus kinase 2-deficient cells. Endocrinology. 148: 5955-65. PMID 17761766 DOI: 10.1210/En.2007-0455  0.824
2007 DiGirolamo DJ, Mukherjee A, Fulzele K, Gan Y, Cao X, Frank SJ, Clemens TL. Mode of growth hormone action in osteoblasts. The Journal of Biological Chemistry. 282: 31666-74. PMID 17698843 DOI: 10.1074/Jbc.M705219200  0.602
2007 Asa SL, Digiovanni R, Jiang J, Ward ML, Loesch K, Yamada S, Sano T, Yoshimoto K, Frank SJ, Ezzat S. A growth hormone receptor mutation impairs growth hormone autofeedback signaling in pituitary tumors. Cancer Research. 67: 7505-11. PMID 17671221 DOI: 10.1158/0008-5472.Can-07-0219  0.783
2007 Deng L, He K, Wang X, Yang N, Thangavel C, Jiang J, Fuchs SY, Frank SJ. Determinants of growth hormone receptor down-regulation. Molecular Endocrinology (Baltimore, Md.). 21: 1537-51. PMID 17488973 DOI: 10.1210/Me.2007-0138  0.743
2007 Rojas-Gil AP, Ziros PG, Kanetsis E, Papathanassopoulou V, Nikolakopoulou NM, He K, Frank SJ, Papavassiliou AG, Spiliotis BE. Combined effect of mutations of the GH1 gene and its proximal promoter region in a child with growth hormone neurosecretory dysfunction (GHND). Journal of Molecular Medicine (Berlin, Germany). 85: 1005-13. PMID 17479231 DOI: 10.1007/S00109-007-0200-7  0.381
2007 Yang N, Wang X, Jiang J, Frank SJ. Role of the growth hormone (GH) receptor transmembrane domain in receptor predimerization and GH-induced activation. Molecular Endocrinology (Baltimore, Md.). 21: 1642-55. PMID 17456794 DOI: 10.1210/Me.2006-0458  0.648
2007 Jiang H, Wang Y, Wu M, Gu Z, Frank SJ, Torres-Diaz R. Growth hormone stimulates hepatic expression of bovine growth hormone receptor messenger ribonucleic acid through signal transducer and activator of transcription 5 activation of a major growth hormone receptor gene promoter. Endocrinology. 148: 3307-15. PMID 17412814 DOI: 10.1210/En.2006-1738  0.453
2007 Frank SJ. Growth hormone, insulin-like growth factor I, and growth: local knowledge. Endocrinology. 148: 1486-8. PMID 17369499 DOI: 10.1210/En.2007-0064  0.394
2007 Reddy GR, Pushpanathan MJ, Ransom RF, Holzman LB, Brosius FC, Diakonova M, Mathieson P, Saleem MA, List EO, Kopchick JJ, Frank SJ, Menon RK. Identification of the glomerular podocyte as a target for growth hormone action. Endocrinology. 148: 2045-55. PMID 17272398 DOI: 10.1210/En.2006-1285  0.466
2007 Han X, Benight N, Osuntokun B, Loesch K, Frank SJ, Denson LA. Tumour necrosis factor α blockade induces an anti-inflammatory growth hormone signalling pathway in experimental colitis Gut. 56: 73-81. PMID 16777921 DOI: 10.1136/Gut.2006.094490  0.809
2006 Han X, Osuntokun B, Benight N, Loesch K, Frank SJ, Denson LA. Signal transducer and activator of transcription 5b promotes mucosal tolerance in pediatric Crohn's disease and murine colitis. The American Journal of Pathology. 169: 1999-2013. PMID 17148664 DOI: 10.2353/Ajpath.2006.060186  0.795
2006 Rojas-Gil AP, Ziros PG, Diaz L, Kletsas D, Basdra EK, Alexandrides TK, Zadik Z, Frank SJ, Papathanassopoulou V, Beratis NG, Papavassiliou AG, Spiliotis BE. Growth hormone/JAK-STAT axis signal-transduction defect. A novel treatable cause of growth failure. The Febs Journal. 273: 3454-66. PMID 16884491 DOI: 10.1111/J.1742-4658.2006.05347.X  0.512
2006 Frank SJ, Wang X, He K, Yang N, Fang P, Rosenfeld RG, Hwa V, Chaudhuri TR, Deng L, Zinn KR. In vivo imaging of hepatic growth hormone signaling. Molecular Endocrinology (Baltimore, Md.). 20: 2819-30. PMID 16803867 DOI: 10.1210/Me.2005-0532  0.687
2006 Huang Y, Li X, Jiang J, Frank SJ. Prolactin modulates phosphorylation, signaling and trafficking of epidermal growth factor receptor in human T47D breast cancer cells Oncogene. 25: 7565-7576. PMID 16785991 DOI: 10.1038/Sj.Onc.1209740  0.512
2006 Loesch K, Deng L, Cowan JW, Wang X, He K, Jiang J, Black RA, Frank SJ. Janus kinase 2 influences growth hormone receptor metalloproteolysis. Endocrinology. 147: 2839-49. PMID 16497804 DOI: 10.1210/En.2005-1484  0.816
2006 Fang P, Kofoed EM, Little BM, Wang X, Ross RJ, Frank SJ, Hwa V, Rosenfeld RG. A mutant signal transducer and activator of transcription 5b, associated with growth hormone insensitivity and insulin-like growth factor-I deficiency, cannot function as a signal transducer or transcription factor. The Journal of Clinical Endocrinology and Metabolism. 91: 1526-34. PMID 16464942 DOI: 10.1210/Jc.2005-2558  0.484
2006 Xu J, Keeton AB, Franklin JL, Li X, Venable DY, Frank SJ, Messina JL. Insulin enhances growth hormone induction of the MEK/ERK signaling pathway. The Journal of Biological Chemistry. 281: 982-92. PMID 16272159 DOI: 10.1074/Jbc.M505484200  0.503
2005 He K, Loesch K, Cowan JW, Li X, Deng L, Wang X, Jiang J, Frank SJ. Janus kinase 2 enhances the stability of the mature growth hormone receptor. Endocrinology. 146: 4755-65. PMID 16081639 DOI: 10.1210/En.2005-0514  0.802
2005 Wang J, Cawley NX, Voutetakis A, Rodriguez YM, Goldsmith CM, Nieman LK, Hoque AT, Frank SJ, Snell CR, Loh YP, Baum BJ. Partial redirection of transgenic human growth hormone secretion from rat salivary glands. Human Gene Therapy. 16: 571-83. PMID 15916482 DOI: 10.1089/Hum.2005.16.571  0.461
2005 Sandberg EM, Ma X, He K, Frank SJ, Ostrov DA, Sayeski PP. Identification of 1,2,3,4,5,6-hexabromocyclohexane as a small molecule inhibitor of jak2 tyrosine kinase autophosphorylation [correction of autophophorylation]. Journal of Medicinal Chemistry. 48: 2526-33. PMID 15801842 DOI: 10.1021/Jm049470K  0.404
2005 Cowan JW, Wang X, Guan R, He K, Jiang J, Baumann G, Black RA, Wolfe MS, Frank SJ. Growth hormone receptor is a target for presenilin-dependent gamma-secretase cleavage. The Journal of Biological Chemistry. 280: 19331-42. PMID 15743767 DOI: 10.1074/Jbc.M500621200  0.788
2004 Jiang J, Wang X, He K, Li X, Chen C, Sayeski PP, Waters MJ, Frank SJ. A conformationally sensitive GHR [growth hormone (GH) receptor] antibody: impact on GH signaling and GHR proteolysis. Molecular Endocrinology (Baltimore, Md.). 18: 2981-96. PMID 15345746 DOI: 10.1210/Me.2004-0102  0.496
2004 Wallace TA, VonDerLinden D, He K, Frank SJ, Sayeski PP. Microarray analyses identify JAK2 tyrosine kinase as a key mediator of ligand-independent gene expression. American Journal of Physiology. Cell Physiology. 287: C981-91. PMID 15189810 DOI: 10.1152/Ajpcell.00085.2004  0.381
2004 Wook Kim J, Rhoads RP, Block SS, Overton TR, Frank SJ, Boisclair YR. Dairy cows experience selective reduction of the hepatic growth hormone receptor during the periparturient period. The Journal of Endocrinology. 181: 281-90. PMID 15128276 DOI: 10.1677/Joe.0.1810281  0.403
2004 Rhoads RP, Kim JW, Leury BJ, Baumgard LH, Segoale N, Frank SJ, Bauman DE, Boisclair YR. Insulin increases the abundance of the growth hormone receptor in liver and adipose tissue of periparturient dairy cows. The Journal of Nutrition. 134: 1020-7. PMID 15113939 DOI: 10.1093/Jn/134.5.1020  0.424
2004 Huang Y, Chang Y, Wang X, Jiang J, Frank SJ. Growth hormone alters epidermal growth factor receptor binding affinity via activation of extracellular signal-regulated kinases in 3T3-F442A cells. Endocrinology. 145: 3297-306. PMID 15070853 DOI: 10.1210/En.2003-1658  0.548
2004 Huang Y, Kim SO, Yang N, Jiang J, Frank SJ. Physical and functional interaction of growth hormone and insulin-like growth factor-I signaling elements. Molecular Endocrinology (Baltimore, Md.). 18: 1471-85. PMID 15044591 DOI: 10.1210/Me.2003-0418  0.649
2004 Yang N, Huang Y, Jiang J, Frank SJ. Caveolar and lipid raft localization of the growth hormone receptor and its signaling elements: impact on growth hormone signaling. The Journal of Biological Chemistry. 279: 20898-905. PMID 15010456 DOI: 10.1074/Jbc.M400625200  0.624
2003 Badger TM, Ronis MJJ, Frank SJ, Chen Y, He L. Effects of chronic ethanol on hepatic and renal CYP2C11 in the male rat: Interactions with the Janus-kinase 2-signal transducer and activators of transcription proteins 5b pathway Endocrinology. 144: 3969-3976. PMID 12933671 DOI: 10.1210/En.2002-0163  0.35
2003 He K, Wang X, Jiang J, Guan R, Bernstein KE, Sayeski PP, Frank SJ. Janus kinase 2 determinants for growth hormone receptor association, surface assembly, and signaling. Molecular Endocrinology (Baltimore, Md.). 17: 2211-27. PMID 12920237 DOI: 10.1210/Me.2003-0256  0.542
2003 Biener E, Martin C, Daniel N, Frank SJ, Centonze VE, Herman B, Djiane J, Gertler A. Ovine placental lactogen-induced heterodimerization of ovine growth hormone and prolactin receptors in living cells is demonstrated by fluorescence resonance energy transfer microscopy and leads to prolonged phosphorylation of signal transducer and activator of transcription (STAT)1 and STAT3. Endocrinology. 144: 3532-40. PMID 12865335 DOI: 10.1210/En.2003-0096  0.516
2003 Wang X, He K, Gerhart M, Jiang J, Paxton RJ, Menon RK, Black RA, Baumann G, Frank SJ. Reduced proteolysis of rabbit growth hormone (GH) receptor substituted with mouse GH receptor cleavage site. Molecular Endocrinology (Baltimore, Md.). 17: 1931-43. PMID 12829808 DOI: 10.1210/Me.2003-0120  0.473
2003 Huang Y, Kim SO, Jiang J, Frank SJ. Growth hormone-induced phosphorylation of epidermal growth factor (EGF) receptor in 3T3-F442A cells. Modulation of EGF-induced trafficking and signaling. The Journal of Biological Chemistry. 278: 18902-13. PMID 12642595 DOI: 10.1074/Jbc.M300939200  0.552
2003 Denson LA, Held MA, Menon RK, Frank SJ, Parlow AF, Arnold DL. Interleukin-6 inhibits hepatic growth hormone signaling via upregulation of Cis and Socs-3. American Journal of Physiology. Gastrointestinal and Liver Physiology. 284: G646-54. PMID 12519742 DOI: 10.1152/Ajpgi.00178.2002  0.402
2002 Beauloye VR, Willems B, de Coninck V, Frank SJ, Edery M, Thissen JP. Impairment of Liver GH Receptor Signaling by Fasting. Endocrinology. 143: 792-800. PMID 28201563 DOI: 10.1210/endo.143.3.8692  0.307
2002 Frank SJ. Minireview: Receptor Dimerization in GH and Erythropoietin Action-It Takes Two to Tango, But How? Endocrinology. 143: 2-10. PMID 28201434 DOI: 10.1210/endo.143.1.8607  0.335
2002 Kim SO, Loesch K, Wang X, Jiang J, Mei L, Cunnick JM, Wu J, Frank SJ. A role for Grb2-associated binder-1 in growth hormone signaling. Endocrinology. 143: 4856-67. PMID 12446613 DOI: 10.1210/En.2002-220565  0.826
2002 Wang X, He K, Gerhart M, Huang Y, Jiang J, Paxton RJ, Yang S, Lu C, Menon RK, Black RA, Baumann G, Frank SJ. Metalloprotease-mediated GH receptor proteolysis and GHBP shedding. Determination of extracellular domain stem region cleavage site. The Journal of Biological Chemistry. 277: 50510-9. PMID 12403792 DOI: 10.1074/Jbc.M208738200  0.513
2002 Baumann G, Frank SJ. Metalloproteinases and the modulation of GH signaling Journal of Endocrinology. 174: 361-368. PMID 12208655 DOI: 10.1677/Joe.0.1740361  0.549
2002 Ji S, Frank SJ, Messina JL. Growth hormone-induced differential desensitization of STAT5, ERK, and Akt phosphorylation. The Journal of Biological Chemistry. 277: 28384-93. PMID 12161450 DOI: 10.1074/Jbc.M111723200  0.568
2002 Beauloye V, Willems B, de Coninck V, Frank SJ, Edery M, Thissen JP. Impairment of liver GH receptor signaling by fasting. Endocrinology. 143: 792-800. PMID 11861499 DOI: 10.1210/Endo.143.3.8692  0.465
2002 Frank SJ. Receptor dimerization in GH and erythropoietin action--it takes two to tango, but how? Endocrinology. 143: 2-10. PMID 11751584 DOI: 10.1210/Endo.143.1.8607  0.452
2001 Frank SJ. Growth hormone signalling and its regulation: Preventing too much of a good thing Growth Hormone and Igf Research. 11: 201-212. PMID 11735235 DOI: 10.1054/Ghir.2001.0237  0.585
2001 Zhang Y, Guan R, Jiang J, Kopchick JJ, Black RA, Baumann G, Frank SJ. Growth Hormone (GH)-induced Dimerization Inhibits Phorbol Ester-stimulated GH Receptor Proteolysis Journal of Biological Chemistry. 276: 24565-24573. PMID 11309389 DOI: 10.1074/Jbc.M101281200  0.595
2001 Lu C, Schwartzbauer G, Sperling MA, Devaskar SU, Thamotharan S, Robbins PD, McTiernan CF, Liu JL, Jiang J, Frank SJ, Menon RK. Demonstration of direct effects of growth hormone on neonatal cardiomyocytes. The Journal of Biological Chemistry. 276: 22892-900. PMID 11303022 DOI: 10.1074/Jbc.M011647200  0.494
2001 Zhao J, Chen H, Peschon JJ, Shi W, Zhang Y, Frank SJ, Warburton D. Pulmonary hypoplasia in mice lacking tumor necrosis factor-α converting enzyme indicates an indispensable role for cell surface protein shedding during embryonic lung branching morphogenesis Developmental Biology. 232: 204-218. PMID 11254358 DOI: 10.1006/Dbio.2001.0176  0.308
2001 Lopez-Perez E, Zhang Y, Frank SJ, Creemers J, Seidah N, Checler F. Constitutive α-secretase cleavage of the β-amyloid precursor protein in the furin-deficient LoVo cell line: Involvement of the pro-hormone convertase 7 and the disintegrin metalloprotease ADAM10 Journal of Neurochemistry. 76: 1532-1539. PMID 11238737 DOI: 10.1046/J.1471-4159.2001.00180.X  0.401
2001 Guan R, Zhang Y, Jiang J, Baumann CA, Black RA, Baumann G, Frank SJ. Phorbol ester- and growth factor-induced growth hormone (GH) receptor proteolysis and GH-binding protein shedding: relationship to GH receptor down-regulation. Endocrinology. 142: 1137-47. PMID 11181529 DOI: 10.1210/Endo.142.3.8030  0.568
2001 Tu Y, Liang L, Frank SJ, Wu C. Src homology 3 domain-dependent interaction of Nck-2 with insulin receptor substrate-1 Biochemical Journal. 354: 315-322. PMID 11171109 DOI: 10.1042/0264-6021:3540315  0.397
2001 Sayeski PP, Showkat Ali M, Frank SJ, Bernstein KE. The Angiotensin II-dependent Nuclear Translocation of Stat1 is Mediated by the Jak2 Protein Motif 231YRFRR Journal of Biological Chemistry. 276: 10556-10563. PMID 11152457 DOI: 10.1074/Jbc.M008856200  0.443
2000 Zhang Y, Jiang J, Black RA, Baumann G, Frank SJ. Tumor Necrosis Factor-α Converting Enzyme (TACE) Is a Growth Hormone Binding Protein (GHBP) Sheddase: The Metalloprotease TACE/ADAM-17 Is Critical for (PMA-Induced) GH Receptor Proteolysis and GHBP Generation. Endocrinology. 141: 4342-4348. PMID 28200876 DOI: 10.1210/endo.141.12.7858  0.341
2000 Zhang Y, Jiang J, Black RA, Baumann G, Frank SJ. Tumor necrosis factor-α converting enzyme (TACE) is a growth hormone binding protein (GHBP) sheddase: The metalloprotease TACE/ADAM-17 is critical for (PMA-induced) GH receptor proteolysis and GHBP generation Endocrinology. 141: 4342-4348. PMID 11108241 DOI: 10.1210/Endo.141.12.7858  0.437
2000 Liang L, Jiang J, Frank SJ. Insulin receptor substrate-1-mediated enhancement of growth hormone-induced mitogen-activated protein kinase activation Endocrinology. 141: 3328-3336. PMID 10965905 DOI: 10.1210/Endo.141.9.7673  0.493
2000 Frank SJ, Messina JL, Baumann G, Black RA, Bertics PJ. Insights into modulation of (and by) growth hormone signaling Journal of Laboratory and Clinical Medicine. 136: 14-20. PMID 10882223 DOI: 10.1067/Mlc.2000.107300  0.454
1999 Kim SO, Houtman JCD, Jiang J, Ruppert JM, Bertics PJ, Frank SJ. Growth hormone-induced alteration in ErbB-2 phosphorylation status in 3T3-F442A fibroblasts Journal of Biological Chemistry. 274: 36015-86024. PMID 10585492 DOI: 10.1074/Jbc.274.50.36015  0.519
1999 Sayeski PP, Ali MS, Safavi A, Lyles M, Kim SO, Frank SJ, Bernstein KE. A catalytically active Jak2 is required for the angiotensin II-dependent activation of Fyn Journal of Biological Chemistry. 274: 33131-33142. PMID 10551884 DOI: 10.1074/jbc.274.46.33131  0.34
1999 Zhang Y, Jiang J, Kopchick JJ, Frank SJ. Disulfide linkage of growth hormone (GH) receptors (GHR) reflects GH- induced GHR dimerization. Association of JAK2 with the GHR is enhanced by receptor dimerization Journal of Biological Chemistry. 274: 33072-33084. PMID 10551877 DOI: 10.1074/Jbc.274.46.33072  0.592
1999 Shoba L, An MR, Frank SJ, Lowe WL. Developmental regulation of insulin-like growth factor-I and growth hormone receptor gene expression Molecular and Cellular Endocrinology. 152: 125-136. PMID 10432230 DOI: 10.1016/S0303-7207(99)00045-3  0.459
1999 Benbassat C, Shoba LNN, Newman M, Adamo ML, Frank SJ, Lowe WL. Growth hormone-mediated regulation of insulin-like growth factor I promoter activity in C6 glioma cells Endocrinology. 140: 3073-3081. PMID 10385399 DOI: 10.1210/Endo.140.7.6762  0.467
1999 Sayeski PP, Ali MS, Hawks K, Frank SJ, Bernstein KE. The angiotensin II-dependent association of Jak2 and c-Src requires the N-terminus of Jak2 and the SH2 domain of c-Src Circulation Research. 84: 1332-1338. PMID 10364571 DOI: 10.1161/01.Res.84.11.1332  0.362
1999 Ji S, Guan R, Frank SJ, Messina JL. Insulin inhibits growth hormone signaling via the growth hormone receptor/JAK2/STAT5B pathway Journal of Biological Chemistry. 274: 13434-13442. PMID 10224108 DOI: 10.1074/Jbc.274.19.13434  0.473
1999 Liang L, Zhou T, Jiang J, Pierce JH, Gustafson TA, Frank SJ. Insulin receptor substrate-1 enhances growth hormone-induced proliferation Endocrinology. 140: 1972-1983. PMID 10218944 DOI: 10.1210/Endo.140.5.6724  0.563
1998 Jiang J, Liang L, Kim SO, Zhang Y, Mandler R, Frank SJ. Growth hormone-dependent tyrosine phosphorylation of a GH receptor-associated high molecular weight protein immunologically related to JAK2 Biochemical and Biophysical Research Communications. 253: 774-779. PMID 9918803 DOI: 10.1006/Bbrc.1998.9793  0.528
1998 Alele J, Jiang J, Goldsmith JF, Yang X, Maheshwari HG, Black RA, Baumann G, Frank SJ. Blockade of growth hormone receptor shedding by a metalloprotease inhibitor Endocrinology. 139: 1927-1935. PMID 9528979 DOI: 10.1210/Endo.139.4.5906  0.522
1998 Kim SO, Jiang J, Yi W, Feng GS, Frank SJ. Involvement of the Src homology 2-containing tyrosine phosphatase SHP-2 in growth hormone signaling Journal of Biological Chemistry. 273: 2344-2354. PMID 9442080 DOI: 10.1074/Jbc.273.4.2344  0.609
1997 Goldsmith JF, Lee SJ, Jiang J, Frank SJ. Growth hormone induces detergent insolubility of GH receptors in IM-9 cells. American Journal of Physiology. Endocrinology and Metabolism. 273: E932-E941. PMID 29585514 DOI: 10.1152/ajpendo.1997.273.5.E932  0.366
1997 Goldsmith JF, Lee SJ, Jiang J, Frank SJ. Growth hormone induces detergent insolubility of GH receptors in IM-9 cells American Journal of Physiology - Endocrinology and Metabolism. 273. PMID 9374679 DOI: 10.1152/Ajpendo.1997.273.5.E932  0.469
1996 Yi W, Kim SO, Jiang J, Park SH, Kraft AS, Waxman DJ, Frank SJ. Growth hormone receptor cytoplasmic domain differentially promotes tyrosine phosphorylation of signal transducers and activators of transcription 5b and 3 by activated JAK2 kinase Molecular Endocrinology. 10: 1425-1443. PMID 8923468 DOI: 10.1210/Mend.10.11.8923468  0.514
1995 Zhao Y, Wagner F, Frank SJ, Kraft AS. The amino-terminal portion of the JAK2 protein kinase is necessary for binding and phosphorylation of the granulocyte-macrophage colony-stimulating factor receptor βc chain Journal of Biological Chemistry. 270: 13814-13818. PMID 7775438 DOI: 10.1074/Jbc.270.23.13814  0.358
1995 Frank SJ, Yi W, Zhao Y, Goldsmith JF, Gilliland G, Jiang J, Sakai I, Kraft AS. Regions of the JAK2 tyrosine kinase required for coupling to the growth hormone receptor Journal of Biological Chemistry. 270: 14776-14785. PMID 7540178 DOI: 10.1074/Jbc.270.24.14776  0.544
1994 Frank SJ, Gilliland G, Van Epps C. Treatment of IM-9 cells with human growth hormone (GH) promotes rapid disulfide linkage of the GH receptor Endocrinology. 135: 148-156. PMID 8013347 DOI: 10.1210/Endo.135.1.8013347  0.518
1994 Frank SJ, Gilliland G, Kraft AS, Arnold CS. Interaction of the growth hormone receptor cytoplasmic domain with the JAK2 tyrosine kinase Endocrinology. 135: 2228-2239. PMID 7956946 DOI: 10.1210/Endo.135.5.7956946  0.483
1992 Frank SJ, Cenciarelli C, Niklinska BB, Letourneur F, Ashwell JD, Weissman AM. Mutagenesis of T cell antigen receptor ζ chain tyrosine residues: Effects on tyrosine phosphorylation and lymphokine production Journal of Biological Chemistry. 267: 13656-13660. PMID 1535630  0.356
1990 Frank SJ, Niklinska BB, Orloff DG, Mercep M, Ashwell JD, Klausner RD. Structural mutations of the T cell receptor ζ chain and its role in T cell activation Science. 249: 174-177. PMID 2371564 DOI: 10.1126/Science.2371564  0.436
1990 Orloff DG, Ra C, Frank SJ, Klausner RD, Kinet JP. Family of disulphide-linked dimers containing the ζ and η chains of the T-cell receptor and the γ chain of Fc receptors Nature. 347: 189-191. PMID 2203969 DOI: 10.1038/347189A0  0.411
1990 Frank SJ, Samelson LE, Klausner RD. The structure and signalling functions of the invariant T cell receptor components Seminars in Immunology. 2: 89-97. PMID 2151801  0.351
1990 Doppman JL, Miller DL, Patronas NJ, Oldfield EH, Merriam GR, Frank SJ, Flack MR, Weintraub BD, Gorden P. The diagnosis of acromegaly: Value of inferior petrosal sinus sampling American Journal of Roentgenology. 154: 1075-1077. PMID 2108545 DOI: 10.2214/Ajr.154.5.2108545  0.384
1989 Weissman AM, Frank SJ, Orloff DG, Mercep M, Ashwell JD, Klausner RD. Role of the zeta chain in the expression of the T cell antigen receptor: Genetic reconstitution studies Embo Journal. 8: 3651-3656. PMID 2583115 DOI: 10.1002/J.1460-2075.1989.Tb08539.X  0.432
1989 Mercep M, Weissman AM, Frank SJ, Klausner RD, Ashwell JD. Activation-driven programmed cell death and T cell receptor ζη expression Science. 246: 1162-1165. PMID 2531464 DOI: 10.1126/Science.2531464  0.371
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