Year |
Citation |
Score |
2023 |
Huang Y, Abdelmagid Abdelgawad AG, Turchinovich A, Queen S, Abreu CM, Zhu X, Batish M, Zheng L, Witwer KW. RNA landscapes of brain tissue and brain tissue-derived extracellular vesicles in simian immunodeficiency virus (SIV) infection and SIV-related central nervous system pathology. Biorxiv : the Preprint Server For Biology. PMID 37034720 DOI: 10.1101/2023.04.01.535193 |
0.342 |
|
2020 |
Zhao Z, Muth DC, Mulka K, Liao Z, Powell BH, Hancock GV, Metcalf Pate KA, Witwer KW. miRNA profiling of primate cervicovaginal lavage and extracellular vesicles reveals miR-186-5p as a potential antiretroviral factor in macrophages. Febs Open Bio. 10: 2021-2039. PMID 33017084 DOI: 10.1002/2211-5463.12952 |
0.486 |
|
2020 |
Huang Y, Cheng L, Turchinovich A, Mahairaki V, Troncoso JC, Pletniková O, Haughey NJ, Vella LJ, Hill AF, Zheng L, Witwer KW. Influence of species and processing parameters on recovery and content of brain tissue-derived extracellular vesicles. Journal of Extracellular Vesicles. 9: 1785746. PMID 32944174 DOI: 10.1080/20013078.2020.1785746 |
0.305 |
|
2020 |
Ahn JY, Datta S, Bandeira E, Cano M, Mallick E, Rai U, Powell B, Tian J, Witwer KW, Handa JT, Paulaitis ME. Release of extracellular vesicle miR-494-3p by ARPE-19 cells with impaired mitochondria. Biochimica Et Biophysica Acta. General Subjects. 129598. PMID 32240720 DOI: 10.1016/J.Bbagen.2020.129598 |
0.313 |
|
2019 |
Pérez PS, Romaniuk MA, Duette GA, Zhao Z, Huang Y, Martin-Jaular L, Witwer KW, Théry C, Ostrowski M. Extracellular vesicles and chronic inflammation during HIV infection. Journal of Extracellular Vesicles. 8: 1687275. PMID 31998449 DOI: 10.1080/20013078.2019.1687275 |
0.374 |
|
2019 |
Gámbaro F, Li Calzi M, Fagúndez P, Costa B, Greif G, Mallick E, Lyons S, Ivanov P, Witwer K, Cayota A, Tosar JP. Stable tRNA halves can be sorted into extracellular vesicles and delivered to recipient cells in a concentration-dependent manner. Rna Biology. 1-15. PMID 31885318 DOI: 10.1080/15476286.2019.1708548 |
0.304 |
|
2019 |
Jeon OH, Wilson DR, Clement CC, Rathod S, Cherry C, Powell B, Lee Z, Khalil AM, Green JJ, Campisi J, Santambrogio L, Witwer KW, Elisseeff JH. Senescence cell-associated extracellular vesicles serve as osteoarthritis disease and therapeutic markers. Jci Insight. 4. PMID 30944259 DOI: 10.1172/Jci.Insight.125019 |
0.34 |
|
2018 |
Clayton A, Buschmann D, Byrd JB, Carter DRF, Cheng L, Compton C, Daaboul G, Devitt A, Falcon-Perez JM, Gardiner C, Gustafson D, Harrison P, Helmbrecht C, Hendrix A, Hill A, ... ... Witwer KW, et al. Summary of the ISEV workshop on extracellular vesicles as disease biomarkers, held in Birmingham, UK, during December 2017. Journal of Extracellular Vesicles. 7: 1473707. PMID 31162490 DOI: 10.1080/20013078.2018.1473707 |
0.322 |
|
2018 |
Théry C, Witwer KW, Aikawa E, Alcaraz MJ, Anderson JD, Andriantsitohaina R, Antoniou A, Arab T, Archer F, Atkin-Smith GK, Ayre DC, Bach JM, Bachurski D, Baharvand H, Balaj L, et al. Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines. Journal of Extracellular Vesicles. 7: 1535750. PMID 30637094 DOI: 10.1080/20013078.2018.1535750 |
0.309 |
|
2018 |
Soekmadji C, Hill AF, Wauben MH, Buzás EI, Di Vizio D, Gardiner C, Lötvall J, Sahoo S, Witwer KW. Towards mechanisms and standardization in extracellular vesicle and extracellular RNA studies: results of a worldwide survey. Journal of Extracellular Vesicles. 7: 1535745. PMID 30370018 DOI: 10.1080/20013078.2018.1535745 |
0.323 |
|
2018 |
Duette G, Pereyra Gerber P, Rubione J, Perez PS, Landay AL, Crowe SM, Liao Z, Witwer KW, Holgado MP, Salido J, Geffner J, Sued O, Palmer CS, Ostrowski M. Induction of HIF-1α by HIV-1 Infection in CD4 T Cells Promotes Viral Replication and Drives Extracellular Vesicle-Mediated Inflammation. Mbio. 9. PMID 30206166 DOI: 10.1128/Mbio.00757-18 |
0.365 |
|
2018 |
Witwer KW. Alternative miRNAs? Human sequences misidentified as plant miRNAs in plant studies and in human plasma. F1000research. 7: 244. PMID 29744036 DOI: 10.12688/F1000Research.14060.1 |
0.379 |
|
2018 |
Muth DC, Powell BH, Zhao Z, Witwer KW. miRNAs in platelet-poor blood plasma and purified RNA are highly stable: a confirmatory study. Bmc Research Notes. 11: 273. PMID 29728133 DOI: 10.1186/S13104-018-3378-6 |
0.419 |
|
2018 |
Chaudhuri AD, Dastgheyb RM, Yoo SW, Trout A, Talbot CC, Hao H, Witwer KW, Haughey NJ. TNFα and IL-1β modify the miRNA cargo of astrocyte shed extracellular vesicles to regulate neurotrophic signaling in neurons. Cell Death & Disease. 9: 363. PMID 29507357 DOI: 10.1038/S41419-018-0369-4 |
0.328 |
|
2017 |
Hu G, Yelamanchili S, Kashanchi F, Haughey N, Bond VC, Witwer KW, Pulliam L, Buch S. Proceedings of the 2017 ISEV symposium on "HIV, NeuroHIV, drug abuse, & EVs". Journal of Neurovirology. PMID 29147885 DOI: 10.1007/S13365-017-0599-8 |
0.33 |
|
2017 |
Beck SE, Queen SE, Metcalf Pate KA, Mangus LM, Abreu CM, Gama L, Witwer KW, Adams RJ, Zink MC, Clements JE, Mankowski JL. An SIV/macaque model targeted to study HIV-associated neurocognitive disorders. Journal of Neurovirology. PMID 28975505 DOI: 10.1007/S13365-017-0582-4 |
0.548 |
|
2017 |
Hu G, Witwer KW, Bond VC, Haughey N, Kashanchi F, Pulliam L, Buch S. Proceedings of the ISEV symposium on "HIV, NeuroAIDS, drug abuse & EVs". Journal of Extracellular Vesicles. 6: 1294360. PMID 28800366 DOI: 10.1080/20013078.2017.1294360 |
0.39 |
|
2017 |
Witwer KW, Zhang CY. Diet-derived microRNAs: unicorn or silver bullet? Genes & Nutrition. 12: 15. PMID 28694875 DOI: 10.1186/S12263-017-0564-4 |
0.38 |
|
2017 |
Liao Z, Muth DC, Eitan E, Travers M, Learman LN, Lehrmann E, Witwer KW. Serum extracellular vesicle depletion processes affect release and infectivity of HIV-1 in culture. Scientific Reports. 7: 2558. PMID 28566772 DOI: 10.1038/S41598-017-02908-5 |
0.388 |
|
2017 |
Roda WC, Li MY, Akinwumi MS, Asahchop EL, Gelman BB, Witwer KW, Power C. Modeling brain lentiviral infections during antiretroviral therapy in AIDS. Journal of Neurovirology. PMID 28512685 DOI: 10.1007/S13365-017-0530-3 |
0.343 |
|
2017 |
Eitan E, Green J, Bodogai M, Mode NA, Bæk R, Jørgensen MM, Freeman DW, Witwer KW, Zonderman AB, Biragyn A, Mattson MP, Noren Hooten N, Evans MK. Age-Related Changes in Plasma Extracellular Vesicle Characteristics and Internalization by Leukocytes. Scientific Reports. 7: 1342. PMID 28465537 DOI: 10.1038/S41598-017-01386-Z |
0.313 |
|
2017 |
Mateescu B, Kowal EJ, van Balkom BW, Bartel S, Bhattacharyya SN, Buzás EI, Buck AH, de Candia P, Chow FW, Das S, Driedonks TA, Fernández-Messina L, Haderk F, Hill AF, Jones JC, ... ... Witwer KW, et al. Obstacles and opportunities in the functional analysis of extracellular vesicle RNA - an ISEV position paper. Journal of Extracellular Vesicles. 6: 1286095. PMID 28326170 DOI: 10.1080/20013078.2017.1286095 |
0.311 |
|
2017 |
Tosar JP, Cayota A, Eitan E, Halushka MK, Witwer KW. Ribonucleic artefacts: are some extracellular RNA discoveries driven by cell culture medium components? Journal of Extracellular Vesicles. 6: 1272832. PMID 28326168 DOI: 10.1080/20013078.2016.1272832 |
0.308 |
|
2016 |
Aigner A, Buesen R, Gant T, Gooderham N, Greim H, Hackermüller J, Hubesch B, Laffont M, Marczylo E, Meister G, Petrick JS, Rasoulpour RJ, Sauer UG, Schmidt K, Seitz H, ... ... Witwer KW, et al. Advancing the use of noncoding RNA in regulatory toxicology: Report of an ECETOC workshop. Regulatory Toxicology and Pharmacology : Rtp. PMID 27663666 DOI: 10.1016/J.Yrtph.2016.09.018 |
0.321 |
|
2016 |
Witwer KW, Halushka MK. Towards the Promise of microRNAs - Enhancing reproducibility and rigor in microRNA research. Rna Biology. 0. PMID 27645402 DOI: 10.1080/15476286.2016.1236172 |
0.4 |
|
2016 |
Auerbach A, Vyas G, Li A, Halushka M, Witwer K. Uptake of dietary milk miRNAs by adult humans: a validation study. F1000research. 5: 721. PMID 27158459 DOI: 10.12688/F1000Research.8548.1 |
0.419 |
|
2016 |
McCall MN, Baras AS, Crits-Christoph A, Ingersoll R, McAlexander MA, Witwer KW, Halushka MK. A benchmark for microRNA quantification algorithms using the OpenArray platform. Bmc Bioinformatics. 17: 138. PMID 27000067 DOI: 10.1186/S12859-016-0987-8 |
0.347 |
|
2016 |
Buchanan EL, Espinoza DA, McAlexander MA, Myers SL, Moyer A, Witwer KW. SAMHD1 transcript upregulation during SIV infection of the central nervous system does not associate with reduced viral load. Scientific Reports. 6: 22629. PMID 26936683 DOI: 10.1038/Srep22629 |
0.37 |
|
2016 |
van Dongen HM, Masoumi N, Witwer KW, Pegtel DM. Extracellular Vesicles Exploit Viral Entry Routes for Cargo Delivery. Microbiology and Molecular Biology Reviews : Mmbr. 80: 369-86. PMID 26935137 DOI: 10.1128/Mmbr.00063-15 |
0.332 |
|
2015 |
Witwer KW. Contamination or artifacts may explain reports of plant miRNAs in humans. The Journal of Nutritional Biochemistry. 26: 1685. PMID 26456566 DOI: 10.1016/J.Jnutbio.2015.09.004 |
0.366 |
|
2015 |
Witwer KW, Buchanan EL, Myers SL, McAlexander MA. miRNAs and SAMHD1 regulation in vitro and in a model of HIV CNS disease. Journal of Neuroinflammation. 12: 159. PMID 26337901 DOI: 10.1186/S12974-015-0380-Y |
0.46 |
|
2015 |
Lee YJ, Kim V, Muth DC, Witwer KW. Validated MicroRNA Target Databases: An Evaluation. Drug Development Research. 76: 389-96. PMID 26286669 DOI: 10.1002/Ddr.21278 |
0.391 |
|
2015 |
Muth DC, McAlexander MA, Ostrenga LJ, Pate NM, Izzi JM, Adams RJ, Pate KA, Beck SE, Karim BO, Witwer KW. Potential role of cervicovaginal extracellular particles in diagnosis of endometriosis. Bmc Veterinary Research. 11: 187. PMID 26253321 DOI: 10.1186/S12917-015-0513-7 |
0.333 |
|
2015 |
El-Diwany R, Wasilewski L, Witwer KW, Bailey JR, Page K, Ray SC, Cox AL, Thomas DL, Balagopal A. Acute Hepatitis C Virus Infection Induces Consistent Changes in Circulating miRNAs that are Associated with Non-Lytic Hepatocyte Release. Journal of Virology. PMID 26157120 DOI: 10.1128/Jvi.00955-15 |
0.393 |
|
2015 |
Tosar JP, Gámbaro F, Sanguinetti J, Bonilla B, Witwer KW, Cayota A. Assessment of small RNA sorting into different extracellular fractions revealed by high-throughput sequencing of breast cell lines. Nucleic Acids Research. 43: 5601-16. PMID 25940616 DOI: 10.1093/Nar/Gkv432 |
0.331 |
|
2015 |
Beck SE, Queen SE, Witwer KW, Metcalf Pate KA, Mangus LM, Gama L, Adams RJ, Clements JE, Christine Zink M, Mankowski JL. Paving the path to HIV neurotherapy: Predicting SIV CNS disease. European Journal of Pharmacology. 759: 303-12. PMID 25818747 DOI: 10.1016/J.Ejphar.2015.03.018 |
0.545 |
|
2015 |
Drewes JL, Meulendyke KA, Liao Z, Witwer KW, Gama L, Ubaida-Mohien C, Li M, Notarangelo FM, Tarwater PM, Schwarcz R, Graham DR, Zink MC. Quinolinic acid/tryptophan ratios predict neurological disease in SIV-infected macaques and remain elevated in the brain under cART. Journal of Neurovirology. PMID 25776527 DOI: 10.1007/S13365-015-0334-2 |
0.358 |
|
2015 |
Witwer KW. Circulating microRNA biomarker studies: pitfalls and potential solutions. Clinical Chemistry. 61: 56-63. PMID 25391989 DOI: 10.1373/Clinchem.2014.221341 |
0.41 |
|
2015 |
Buchanan EL, McAlexander MA, Witwer KW. SAMHD1 expression in blood cells of HIV-1 elite suppressors and viraemic progressors. The Journal of Antimicrobial Chemotherapy. 70: 954-6. PMID 25344600 DOI: 10.1093/Jac/Dku428 |
0.356 |
|
2014 |
Lötvall J, Hill AF, Hochberg F, Buzás EI, Di Vizio D, Gardiner C, Gho YS, Kurochkin IV, Mathivanan S, Quesenberry P, Sahoo S, Tahara H, Wauben MH, Witwer KW, Théry C. Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular Vesicles. Journal of Extracellular Vesicles. 3: 26913. PMID 25536934 DOI: 10.3402/Jev.V3.26913 |
0.305 |
|
2014 |
Witwer KW. Diet-responsive mammalian miRNAs are likely endogenous. The Journal of Nutrition. 144: 1880-1. PMID 25332488 DOI: 10.3945/Jn.114.202523 |
0.376 |
|
2014 |
Christofidou-Solomidou M, Pietrofesa R, Arguiri E, McAlexander MA, Witwer KW. Dietary flaxseed modulates the miRNA profile in irradiated and non-irradiated murine lungs: a novel mechanism of tissue radioprotection by flaxseed. Cancer Biology & Therapy. 15: 930-7. PMID 24755684 DOI: 10.4161/Cbt.28905 |
0.37 |
|
2014 |
Witwer KW, Gama L, Mankowski JL, Zink MC, Clements JE. TRIM19-positive and TRIM19-negative cells in and around a perivascular cuff of CD68-positive macrophages. Aids Research and Human Retroviruses. 30: 333-4. PMID 24697643 DOI: 10.1089/Aid.2014.0029 |
0.548 |
|
2014 |
Meulendyke KA, Ubaida-Mohien C, Drewes JL, Liao Z, Gama L, Witwer KW, Graham DR, Zink MC. Elevated brain monoamine oxidase activity in SIV- and HIV-associated neurological disease. The Journal of Infectious Diseases. 210: 904-12. PMID 24688074 DOI: 10.1093/Infdis/Jiu194 |
0.374 |
|
2014 |
Witwer KW. HIV-1 Tat- and Vpr-responsive microRNAs of neuronal cells. The Journal of Biological Chemistry. 289: 3104. PMID 24489003 DOI: 10.1074/Jbc.L113.541755 |
0.382 |
|
2014 |
Witwer KW, Hirschi KD. Transfer and functional consequences of dietary microRNAs in vertebrates: concepts in search of corroboration: negative results challenge the hypothesis that dietary xenomiRs cross the gut and regulate genes in ingesting vertebrates, but important questions persist. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 36: 394-406. PMID 24436255 DOI: 10.1002/Bies.201300150 |
0.412 |
|
2014 |
Yu IW, Espinoza DA, McAlexander MA, Witwer KW. OpenArray profiling reveals no differential modulation of miRNA by positive and negative CD4+ T cell immunoselection. Experimental Hematology. 42: 11-3. PMID 24096121 DOI: 10.1016/J.Exphem.2013.09.011 |
0.428 |
|
2014 |
Gao P, Witwer K, McAlexander M, Tripathi P, Johnson T, Li HH. Circulating Extracellular Micrornas In Hereditary Angioedema Journal of Allergy and Clinical Immunology. 133: AB32. DOI: 10.1016/J.Jaci.2013.12.141 |
0.389 |
|
2013 |
Liu J, Sisk JM, Gama L, Clements JE, Witwer KW. Tristetraprolin expression and microRNA-mediated regulation during simian immunodeficiency virus infection of the central nervous system. Molecular Brain. 6: 40. PMID 24103357 DOI: 10.1186/1756-6606-6-40 |
0.581 |
|
2013 |
Witwer KW, Buzás EI, Bemis LT, Bora A, Lässer C, Lötvall J, Nolte-'t Hoen EN, Piper MG, Sivaraman S, Skog J, Théry C, Wauben MH, Hochberg F. Standardization of sample collection, isolation and analysis methods in extracellular vesicle research. Journal of Extracellular Vesicles. 2. PMID 24009894 DOI: 10.3402/Jev.V2I0.20360 |
0.328 |
|
2013 |
Sisk JM, Witwer KW, Tarwater PM, Clements JE. SIV replication is directly downregulated by four antiviral miRNAs. Retrovirology. 10: 95. PMID 23988154 DOI: 10.1186/1742-4690-10-95 |
0.621 |
|
2013 |
Witwer KW, McAlexander MA, Queen SE, Adams RJ. Real-time quantitative PCR and droplet digital PCR for plant miRNAs in mammalian blood provide little evidence for general uptake of dietary miRNAs: limited evidence for general uptake of dietary plant xenomiRs. Rna Biology. 10: 1080-6. PMID 23770773 DOI: 10.4161/Rna.25246 |
0.393 |
|
2013 |
McAlexander MA, Phillips MJ, Witwer KW. Comparison of Methods for miRNA Extraction from Plasma and Quantitative Recovery of RNA from Cerebrospinal Fluid. Frontiers in Genetics. 4: 83. PMID 23720669 DOI: 10.3389/Fgene.2013.00083 |
0.312 |
|
2013 |
Witwer KW. Data submission and quality in microarray-based microRNA profiling. Clinical Chemistry. 59: 392-400. PMID 23358751 DOI: 10.1373/Clinchem.2012.193813 |
0.323 |
|
2013 |
Sisk J, Clements J, Witwer K. Witwer, K.W.; et al. Correction: miRNA Profiles of Monocyte-Lineage Cells Are Consistent with Complicated Roles in HIV-1 Restriction. Viruses 2012, 4, 1844-1864. Viruses. 5: 901-901. DOI: 10.3390/V5030901 |
0.556 |
|
2012 |
Sisk JM, Clements JE, Witwer KW. miRNA profiles of monocyte-lineage cells are consistent with complicated roles in HIV-1 restriction. Viruses. 4: 1844-64. PMID 23202444 DOI: 10.3390/V4101844 |
0.615 |
|
2012 |
Witwer KW. XenomiRs and miRNA homeostasis in health and disease: evidence that diet and dietary miRNAs directly and indirectly influence circulating miRNA profiles. Rna Biology. 9: 1147-54. PMID 22951590 DOI: 10.4161/Rna.21619 |
0.407 |
|
2012 |
Witwer KW, Clements JE. Evidence for miRNA expression differences of HIV-1-positive, treatment-naive patients and elite suppressors: a re-analysis. Blood. 119: 6395-6. PMID 22745299 DOI: 10.1182/Blood-2012-02-412742 |
0.59 |
|
2012 |
Witwer KW, Watson AK, Blankson JN, Clements JE. Relationships of PBMC microRNA expression, plasma viral load, and CD4+ T-cell count in HIV-1-infected elite suppressors and viremic patients. Retrovirology. 9: 5. PMID 22240256 DOI: 10.1186/1742-4690-9-5 |
0.615 |
|
2012 |
Watson AK, Witwer KW. Do platform-specific factors explain microRNA profiling disparities? Clinical Chemistry. 58: 472-4; author reply . PMID 22048406 DOI: 10.1373/Clinchem.2011.175281 |
0.397 |
|
2011 |
Co JG, Witwer KW, Gama L, Zink MC, Clements JE. Induction of innate immune responses by SIV in vivo and in vitro: differential expression and function of RIG-I and MDA5. The Journal of Infectious Diseases. 204: 1104-14. PMID 21881126 DOI: 10.1093/Infdis/Jir469 |
0.534 |
|
2011 |
Witwer KW, Sarbanes SL, Liu J, Clements JE. A plasma microRNA signature of acute lentiviral infection: biomarkers of central nervous system disease. Aids (London, England). 25: 2057-67. PMID 21857495 DOI: 10.1097/Qad.0B013E32834B95Bf |
0.602 |
|
2010 |
Witwer KW, Sisk JM, Gama L, Clements JE. MicroRNA regulation of IFN-beta protein expression: rapid and sensitive modulation of the innate immune response. Journal of Immunology (Baltimore, Md. : 1950). 184: 2369-76. PMID 20130213 DOI: 10.4049/Jimmunol.0902712 |
0.556 |
|
2009 |
Witwer KW, Gama L, Li M, Bartizal CM, Queen SE, Varrone JJ, Brice AK, Graham DR, Tarwater PM, Mankowski JL, Zink MC, Clements JE. Coordinated regulation of SIV replication and immune responses in the CNS. Plos One. 4: e8129. PMID 20019816 DOI: 10.1371/Journal.Pone.0008129 |
0.556 |
|
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