Year |
Citation |
Score |
2023 |
Palani CD, Zhu X, Alagar M, Attucks OC, Pace BS. Bach1 inhibitor HPP-D mediates γ-globin gene activation in sickle erythroid progenitors. Blood Cells, Molecules & Diseases. 104: 102792. PMID 37633023 DOI: 10.1016/j.bcmd.2023.102792 |
0.431 |
|
2023 |
Xi C, Pang J, Zhi W, Chang CS, Siddaramappa U, Shi H, Horuzsko A, Pace B, Zhu X. Nrf2 sensitizes ferroptosis through L-2-hydroxyglutarate-mediated chromatin modifications in sickle cell disease. Blood. PMID 37267508 DOI: 10.1182/blood.2022018159 |
0.333 |
|
2022 |
Gu Q, Palani CD, Smith A, Li B, Amos-Abanyie EK, Ogu U, Lu L, Pace BS, Starlard-Davenport A. MicroRNA29B induces fetal hemoglobin inhibition of the HBG repressor protein MYB and in humanized sickle cell mice. Frontiers in Medicine. 9: 1043686. PMID 36507536 DOI: 10.3389/fmed.2022.1043686 |
0.389 |
|
2022 |
Lopez NH, Li B, Palani C, Siddaramappa U, Takezaki M, Xu H, Zhi W, Pace BS. Salubrinal induces fetal hemoglobin expression via the stress-signaling pathway in human sickle erythroid progenitors and sickle cell disease mice. Plos One. 17: e0261799. PMID 35639781 DOI: 10.1371/journal.pone.0261799 |
0.347 |
|
2021 |
Junker LH, Li B, Zhu X, Koti S, Cerbone RE, Hendrick CL, Sangerman J, Perrine S, Pace BS. Novel histone deacetylase inhibitor CT-101 induces γ-globin gene expression in sickle erythroid progenitors with targeted epigenetic effects. Blood Cells, Molecules & Diseases. 93: 102626. PMID 34856533 DOI: 10.1016/j.bcmd.2021.102626 |
0.357 |
|
2021 |
Starlard-Davenport A, Fitzgerald A, Pace BS. Exploring epigenetic and microRNA approaches for γ-globin gene regulation. Experimental Biology and Medicine (Maywood, N.J.). 15353702211028195. PMID 34292080 DOI: 10.1177/15353702211028195 |
0.426 |
|
2021 |
Starlard-Davenport A, Fitzgerald A, Pace BS. Exploring epigenetic and microRNA approaches for γ-globin gene regulation. Experimental Biology and Medicine (Maywood, N.J.). 15353702211028195. PMID 34292080 DOI: 10.1177/15353702211028195 |
0.426 |
|
2021 |
Pace BS, Perrine S, Li B, Makala L, Xu H, Takezaki M, Wolf RF, Wang A, Xu X, Huang J, Alimardanov A, Tawa GJ, Sangerman J, Faller A, Zheng W, et al. Benserazide racemate and enantiomers induce fetal globin gene expression in vivo: Studies to guide clinical development for beta thalassemia and sickle cell disease. Blood Cells, Molecules & Diseases. 89: 102561. PMID 33744514 DOI: 10.1016/j.bcmd.2021.102561 |
0.4 |
|
2020 |
Zhu X, Xi C, Ward A, Takezaki M, Shi H, Peterson KR, Pace BS. NRF2 mediates γ-globin gene regulation through epigenetic modifications in a β-YAC transgenic mouse model. Experimental Biology and Medicine (Maywood, N.J.). 1535370220945305. PMID 32715783 DOI: 10.1177/1535370220945305 |
0.543 |
|
2019 |
Liu L, Zhu X, Yu A, Ward CM, Pace BS. δ-Aminolevulinate induces fetal hemoglobin expression by enhancing cellular heme biosynthesis. Experimental Biology and Medicine (Maywood, N.J.). 1535370219872995. PMID 31475864 DOI: 10.1177/1535370219872995 |
0.401 |
|
2019 |
Oseghale AR, Zhu X, Li B, Peterson KR, Nudelman A, Rephaeli A, Xu H, Pace BS. Conjugate prodrug AN-233 induces fetal hemoglobin expression in sickle erythroid progenitors and β-YAC transgenic mice. Blood Cells, Molecules & Diseases. 79: 102345. PMID 31351219 DOI: 10.1016/J.Bcmd.2019.102345 |
0.511 |
|
2019 |
Starlard-Davenport A, Smith A, Vu L, Li B, Pace BS. MIR29B mediates epigenetic mechanisms of HBG gene activation. British Journal of Haematology. PMID 30891745 DOI: 10.1111/Bjh.15870 |
0.474 |
|
2019 |
Zhu X, Oseghale AR, Nicole LH, Li B, Pace BS. Mechanisms of NRF2 activation to mediate fetal hemoglobin induction and protection against oxidative stress in sickle cell disease. Experimental Biology and Medicine (Maywood, N.J.). 1535370219825859. PMID 30674214 DOI: 10.1177/1535370219825859 |
0.408 |
|
2019 |
Siddaramappa UN, Patel N, Pace BS, Kutlar A. Downregulation of Cytoskeletal Protein Kazrin in Lung Endothelial Cells of Preclinical Sickle Cell Disease Mouse Model - Essential Role of Endothelial Barrier Function Blood. 134: 2258-2258. DOI: 10.1182/Blood-2019-130924 |
0.349 |
|
2018 |
Li B, Zhu X, Ward CM, Starlard-Davenport A, Takezaki M, Berry A, Ward A, Wilder C, Neunert C, Kutlar A, Pace BS. MIR-144 Mediated NRF2 Gene Silencing Inhibits Fetal Hemoglobin Expression in Sickle Cell Disease. Experimental Hematology. PMID 30412705 DOI: 10.1016/J.Exphem.2018.11.002 |
0.396 |
|
2018 |
Li B, Zhu X, Hossain MA, Guy CR, Xu H, Bungert J, Pace BS. Fetal hemoglobin induction in sickle erythroid progenitors using a synthetic zinc finger DNA-binding domain. Haematologica. PMID 29622657 DOI: 10.3324/Haematol.2017.185967 |
0.398 |
|
2018 |
Zhu X, Ward AH, Xi C, Pace BS. NRF2 Mediates Epigenetic Changes in DNA and Chromatin Structure to Regulate γ-Globin Gene Expression in a Human βYAC Transgenic Mouse Model Blood. 132: 1053-1053. DOI: 10.1182/Blood-2018-99-116438 |
0.589 |
|
2017 |
Zhu X, Xi C, Thomas B, Pace BS. Loss of NRF2 function exacerbates the pathophysiology of sickle cell disease in a transgenic mouse model. Blood. PMID 29255069 DOI: 10.1182/Blood-2017-10-810531 |
0.428 |
|
2017 |
Krishnamoorthy S, Pace B, Gupta D, Sturtevant S, Li B, Makala L, Brittain J, Moore N, Vieira BF, Thullen T, Stone I, Li H, Hobbs WE, Light DR. Dimethyl fumarate increases fetal hemoglobin, provides heme detoxification, and corrects anemia in sickle cell disease. Jci Insight. 2. PMID 29046485 DOI: 10.1172/Jci.Insight.96409 |
0.501 |
|
2017 |
Zhu X, Li B, Pace BS. NRF2 mediates γ-globin gene regulation and fetal hemoglobin induction in human erythroid progenitors. Haematologica. PMID 28473619 DOI: 10.3324/Haematol.2016.160788 |
0.461 |
|
2016 |
Hossain MA, Shen Y, Knudson I, Thakur S, Stees JR, Qiu Y, Pace BS, Peterson KR, Bungert J. Activation of Fetal γ-globin Gene Expression via Direct Protein Delivery of Synthetic Zinc-finger DNA-Binding Domains. Molecular Therapy. Nucleic Acids. 5: e378. PMID 28131280 DOI: 10.1038/mtna.2016.85 |
0.498 |
|
2016 |
Hossain MA, Shen Y, Knudson I, Thakur S, Stees JR, Qiu Y, Pace BS, Peterson KR, Bungert J. Activation of Fetal γ-globin Gene Expression via Direct Protein Delivery of Synthetic Zinc-finger DNA-Binding Domains. Molecular Therapy. Nucleic Acids. 5: e378. PMID 27754490 DOI: 10.1038/Mtna.2016.85 |
0.578 |
|
2016 |
Liu L, Pertsemlidis A, Ding LH, Story MD, Steinberg MH, Sebastiani P, Hoppe C, Ballas SK, Pace BS. A case-control genome-wide association study identifies genetic modifiers of fetal hemoglobin in sickle cell disease. Experimental Biology and Medicine (Maywood, N.J.). PMID 27022141 DOI: 10.1177/1535370216642047 |
0.464 |
|
2016 |
Ward CM, Li B, Pace BS. Stable expression of miR-34a mediates fetal hemoglobin induction in K562 cells. Experimental Biology and Medicine (Maywood, N.J.). PMID 26940952 DOI: 10.1177/1535370216636725 |
0.49 |
|
2016 |
Krishnamoorthy S, Gupta D, Hobbs WE, Loh C, Light DR, Peters R, Sturtevant S, Pace B, Nakamura Y, Lucas B, Vieira BF. Nrf2 Activation and Fetal Hemoglobin Induction in Sickle Cell Disease Blood. 128: 4840-4840. DOI: 10.1182/Blood.V128.22.4840.4840 |
0.495 |
|
2015 |
Boosalis MS, Sangerman JI, White GL, Wolf RF, Shen L, Dai Y, White E, Makala LH, Li B, Pace BS, Nouraie M, Faller DV, Perrine SP. Novel Inducers of Fetal Globin Identified through High Throughput Screening (HTS) Are Active In Vivo in Anemic Baboons and Transgenic Mice. Plos One. 10: e0144660. PMID 26713848 DOI: 10.1371/Journal.Pone.0144660 |
0.467 |
|
2015 |
Cai Y, Pi W, Sivaprakasam S, Zhu X, Zhang M, Chen J, Makala L, Lu C, Wu J, Teng Y, Pace B, Tuan D, Singh N, Li H. UFBP1, a Key Component of the Ufm1 Conjugation System, Is Essential for Ufmylation-Mediated Regulation of Erythroid Development. Plos Genetics. 11: e1005643. PMID 26544067 DOI: 10.1371/Journal.Pgen.1005643 |
0.468 |
|
2015 |
Pace BS, Liu L, Li B, Makala LH. Cell signaling pathways involved in drug-mediated fetal hemoglobin induction: Strategies to treat sickle cell disease. Experimental Biology and Medicine (Maywood, N.J.). 240: 1050-64. PMID 26283707 DOI: 10.1177/1535370215596859 |
0.503 |
|
2015 |
Subbanna S, Nagre NN, Umapathy NS, Pace BS, Basavarajappa BS. Ethanol exposure induces neonatal neurodegeneration by enhancing CB1R Exon1 histone H4K8 acetylation and up-regulating CB1R function causing neurobehavioral abnormalities in adult mice. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25609594 DOI: 10.1093/Ijnp/Pyu028 |
0.302 |
|
2015 |
Peterson KR, Makala LC, Takezaki M, Barbas CF, Pace B. Induction of Fetal Hemoglobin and Reduction of Disease Pathology in Sickle Cell Mice By a Synthetic Zinc Finger Gamma-Globin Activator Blood. 126: 962-962. DOI: 10.1182/Blood.V126.23.962.962 |
0.424 |
|
2015 |
Krishnamoorthy S, Gupta D, Sturtevant S, Li B, Makala LC, Hobbs WE, Light DR, Pace B. Dimethyl Fumarate Induces Fetal Hemoglobin in Sickle Cell Disease Blood. 126: 410-410. DOI: 10.1182/Blood.V126.23.410.410 |
0.53 |
|
2015 |
Liu L, Torres C, Kang B, Pace B. Delta-Aminolevulinate Preferentially Induces Gamma-Globin Expression in Erythroid Cells through Activation of NRF2 Stress Response Blood. 126: 3387-3387. DOI: 10.1182/Blood.V126.23.3387.3387 |
0.537 |
|
2015 |
Zhang Y, Crosby JR, Boerwinkle E, Pace B, Sheehan VA. Pharmacological Induction of FOXO3 Is a Potential Treatment for Sickle Cell Disease Blood. 126: 282-282. DOI: 10.1182/Blood.V126.23.282.282 |
0.541 |
|
2014 |
Peterson KR, Costa FC, Fedosyuk H, Neades RY, Chazelle AM, Zelenchuk L, Fonteles AH, Dalal P, Roy A, Chaguturu R, Li B, Pace BS. A cell-based high-throughput screen for novel chemical inducers of fetal hemoglobin for treatment of hemoglobinopathies. Plos One. 9: e107006. PMID 25225870 DOI: 10.1371/Journal.Pone.0107006 |
0.424 |
|
2014 |
Li B, Ding L, Yang C, Kang B, Liu L, Story MD, Pace BS. Characterization of transcription factor networks involved in umbilical cord blood CD34+ stem cells-derived erythropoiesis. Plos One. 9: e107133. PMID 25211130 DOI: 10.1371/Journal.Pone.0107133 |
0.461 |
|
2014 |
Menzel S, Rooks H, Zelenika D, Mtatiro SN, Gnanakulasekaran A, Drasar E, Cox S, Liu L, Masood M, Silver N, Garner C, Vasavda N, Howard J, Makani J, Adekile A, ... Pace B, et al. Global Genetic Architecture of an Erythroid Quantitative Trait Locus, HMIP-2. Annals of Human Genetics. PMID 25069958 DOI: 10.1111/Ahg.12077 |
0.33 |
|
2014 |
Promsote W, Makala L, Li B, Smith SB, Singh N, Ganapathy V, Pace BS, Martin PM. Monomethylfumarate induces γ-globin expression and fetal hemoglobin production in cultured human retinal pigment epithelial (RPE) and erythroid cells, and in intact retina. Investigative Ophthalmology & Visual Science. 55: 5382-93. PMID 24825111 DOI: 10.1167/Iovs.14-14179 |
0.338 |
|
2014 |
Perrine SP, Pace BS, Faller DV. Targeted fetal hemoglobin induction for treatment of beta hemoglobinopathies. Hematology/Oncology Clinics of North America. 28: 233-48. PMID 24589264 DOI: 10.1016/J.Hoc.2013.11.009 |
0.48 |
|
2014 |
Li B, Torres CM, Takezaki M, Neunert C, Kutlar A, Pace BS. Micro RNA Profiling to Identify Regulator of Fetal Hemoglobin Expression in Sickle Cell Disease Blood. 124: 49-49. DOI: 10.1182/Blood.V124.21.49.49 |
0.39 |
|
2013 |
Liu L, Karmakar S, Dhar R, Mahajan M, Choudhury A, Weissman S, Pace BS. Regulation of Gγ-globin gene by ATF2 and its associated proteins through the cAMP-response element. Plos One. 8: e78253. PMID 24223142 DOI: 10.1371/Journal.Pone.0078253 |
0.554 |
|
2013 |
Peterson KR, Costa FC, Fedosyuk H, Neades R, Chazelle AM, Zelenchuk L, Fonteles AH, Dalal P, Donover P, Reichman M, Roy A, Chaguturu R, Biaoru L, Pace BS. A Cell-Based High-Throughput Screen For Novel Inducers Of Fetal Hemoglobin For Treatment Of Sickle Cell Disease, Cooley’s Anemia and β-Thalassemias Blood. 122: 925-925. DOI: 10.1182/Blood.V122.21.925.925 |
0.431 |
|
2013 |
Pace BS, Sangerman JI, Boosalis MS, Wolf R, Dai Y, Chui DH, Makala L, Li B, Faller DV, Perrine SP. Next Generation Clinical-Stage HbF Inducers Exhibit Multiple Molecular Actions In Vitro and In Vivo and Offer Personalized Therapeutic Regimens Blood. 122: 560-560. DOI: 10.1182/Blood.V122.21.560.560 |
0.473 |
|
2013 |
Makala L, Promsote W, Li B, Ganapathy V, Pamela M, Pace BS. Monomethylfumarate (MMF), a Novel Inducer Of Fetal Hemoglobin In Human Erythroid Progenitors and Retinal Pigment Epithelial Cells Blood. 122: 317-317. DOI: 10.1182/Blood.V122.21.317.317 |
0.431 |
|
2012 |
Pace BS, Ofori-Acquah SF, Peterson KR. Sickle cell disease: genetics, cellular and molecular mechanisms, and therapies. Anemia. 2012: 143594. PMID 22957221 DOI: 10.1155/2012/143594 |
0.434 |
|
2012 |
Makala L, Di Maro S, Lou TF, Sivanand S, Ahn JM, Pace BS. FK228 Analogues Induce Fetal Hemoglobin in Human Erythroid Progenitors. Anemia. 2012: 428137. PMID 22655179 DOI: 10.1155/2012/428137 |
0.351 |
|
2012 |
Li B, Ding L, Li W, Story MD, Pace BS. Characterization of the transcriptome profiles related to globin gene switching during in vitro erythroid maturation. Bmc Genomics. 13: 153. PMID 22537182 DOI: 10.1186/1471-2164-13-153 |
0.578 |
|
2012 |
Li B, Ding L, Yang C, Story M, Pace BS. Transcription Factor Networks Involved in Fetal Stem Cell Erythropoiesis Blood. 120: 3444-3444. DOI: 10.1182/Blood.V120.21.3444.3444 |
0.558 |
|
2012 |
Agyekum DG, Chen Z, Xiao H, Yu M, Patel N, Pace BS, Meiler SE. Resveratrol Regulates Fetal Hemoglobin Production by Inhibiting KLF1 and BCL11A in KU812 Cells Blood. 120: 1000-1000. DOI: 10.1182/Blood.V120.21.1000.1000 |
0.459 |
|
2011 |
Kalra IS, Alam MM, Choudhary PK, Pace BS. Krüppel-like Factor 4 activates HBG gene expression in primary erythroid cells. British Journal of Haematology. 154: 248-59. PMID 21539536 DOI: 10.1111/J.1365-2141.2011.08710.X |
0.823 |
|
2011 |
Ramakrishnan V, Pace BS. Regulation of γ-globin gene expression involves signaling through the p38 MAPK/CREB1 pathway. Blood Cells, Molecules & Diseases. 47: 12-22. PMID 21497119 DOI: 10.1016/J.Bcmd.2011.03.003 |
0.651 |
|
2011 |
Muralidhar SA, Ramakrishnan V, Kalra IS, Li W, Pace BS. Histone deacetylase 9 activates gamma-globin gene expression in primary erythroid cells. The Journal of Biological Chemistry. 286: 2343-53. PMID 21078662 DOI: 10.1074/Jbc.M110.115725 |
0.77 |
|
2011 |
Pace BS, Makala LH. The hemoglobin regulatory regions Gene Regulatory Sequences and Human Disease. 19-40. DOI: 10.1007/978-1-4614-1683-8_2 |
0.412 |
|
2010 |
Zein S, Li W, Ramakrishnan V, Lou TF, Sivanand S, Mackie A, Pace B. Identification of fetal hemoglobin-inducing agents using the human leukemia KU812 cell line. Experimental Biology and Medicine (Maywood, N.J.). 235: 1385-94. PMID 20975082 DOI: 10.1258/Ebm.2010.010129 |
0.693 |
|
2010 |
Hebbel RP, Vercellotti GM, Pace BS, Solovey AN, Kollander R, Abanonu CF, Nguyen J, Vineyard JV, Belcher JD, Abdulla F, Osifuye S, Eaton JW, Kelm RJ, Slungaard A. The HDAC inhibitors trichostatin A and suberoylanilide hydroxamic acid exhibit multiple modalities of benefit for the vascular pathobiology of sickle transgenic mice. Blood. 115: 2483-90. PMID 20053759 DOI: 10.1182/Blood-2009-02-204990 |
0.343 |
|
2010 |
Kodeboyina S, Balamurugan P, Liu L, Pace BS. cJun modulates Ggamma-globin gene expression via an upstream cAMP response element. Blood Cells, Molecules & Diseases. 44: 7-15. PMID 19861239 DOI: 10.1016/J.Bcmd.2009.10.002 |
0.482 |
|
2010 |
Kalra IS, Alam MM, Pace BS. Transcriptional Regulation of γ-Globin Gene Expression by KLF4 Blood. 116: 645-645. DOI: 10.1182/Blood.V116.21.645.645 |
0.835 |
|
2010 |
Li B, Ding L, Li W, Lou T, Story M, Pace B. Identification of Proteins Involved In Globin Gene Expression During Erythroid Maturation Using An In Vitro Erythroid Liquid Culture System Blood. 116: 2065-2065. DOI: 10.1182/Blood.V116.21.2065.2065 |
0.571 |
|
2010 |
Ramakrishnan V, Liu L, Karmakar S, Mahajan M, Weissman SM, Pace B. The Role of p38 MAPK/CREB1 Signaling In γ-Globin Gene Regulation Blood. 116: 1012-1012. DOI: 10.1182/Blood.V116.21.1012.1012 |
0.702 |
|
2009 |
Lou TF, Singh M, Mackie A, Li W, Pace BS. Hydroxyurea generates nitric oxide in human erythroid cells: mechanisms for gamma-globin gene activation. Experimental Biology and Medicine (Maywood, N.J.). 234: 1374-82. PMID 19657070 DOI: 10.3181/0811-Rm-339 |
0.451 |
|
2009 |
Yao X, Kodeboyina S, Liu L, Dzandu J, Sangerman J, Ofori-Acquah SF, Pace BS. Role of STAT3 and GATA-1 interactions in gamma-globin gene expression. Experimental Hematology. 37: 889-900. PMID 19447160 DOI: 10.1016/J.Exphem.2009.05.004 |
0.558 |
|
2009 |
Liu L, Muralidhar S, Singh M, Sylvan C, Kalra IS, Quinn CT, Onyekwere OC, Pace BS. High-density SNP genotyping to define beta-globin locus haplotypes. Blood Cells, Molecules & Diseases. 42: 16-24. PMID 18829352 DOI: 10.1016/J.Bcmd.2008.07.002 |
0.698 |
|
2009 |
Ramakrishnan V, Bhattacharya K, Pace B. Role of Upstream cAMP Response Element (CRE) in γ-Globin Gene Regulation. Blood. 114: 4076-4076. DOI: 10.1182/Blood.V114.22.4076.4076 |
0.682 |
|
2009 |
Kalra IS, Li W, Muralidhar S, Pace B. Role of KLF4 and KLF12 in γ-Globin Gene Regulation. Blood. 114: 4075-4075. DOI: 10.1182/Blood.V114.22.4075.4075 |
0.785 |
|
2009 |
Muralidhar SA, Pace B. Role of HDAC9 in γ-Globin Gene Regulation. Blood. 114: 4074-4074. DOI: 10.1182/Blood.V114.22.4074.4074 |
0.84 |
|
2009 |
Hebbel RP, Vercellotti GM, Pace B, Solovey A, Kollander R, Abanonu C, Nguyen J, Vineyard JV, Belcher JD, Abdulla F, Osifuye S, Eaton JW, Kelm R, Slungaard A. The HDAC Inhibitors Trichostatin A (TSA) and Suberoylanilide Hydroxamic Acid (SAHA) Exhibit Multiple Modalities of Benefit for the Vascular Pathology of Sickle Disease. Blood. 114: 2586-2586. DOI: 10.1182/Blood.V114.22.2586.2586 |
0.339 |
|
2008 |
Nimer S, Muralidhar SA, Pace B. The Role of HDAC10 in γ-Globin Gene Regulation Blood. 112: 5412-5412. DOI: 10.1182/Blood.V112.11.5412.5412 |
0.837 |
|
2008 |
Kodeboyina S, Zein S, Lee M, Balamurugan P, Yao X, Pace B. Role of Cjun in Gγ-Globin Gene Trans-Activation. Blood. 112: 1870-1870. DOI: 10.1182/Blood.V112.11.1870.1870 |
0.498 |
|
2008 |
Muralidhar SA, Nimer S, Pace B. Characterization of Histone Deacetyalses Involved in γ-Globin Gene Regulation. Blood. 112: 1869-1869. DOI: 10.1182/Blood.V112.11.1869.1869 |
0.838 |
|
2007 |
Pace BS, Seung Lee M, Yao X, Zein S, Sangerman J. Histone deacetylase inhibitors induce γ-globin expression by p38 MAPK-mediated CREB and ATF-2 activation Blood Cells, Molecules, and Diseases. 38: 166. DOI: 10.1016/J.Bcmd.2006.10.106 |
0.434 |
|
2007 |
Liu L, Bu C, Pace B. Structural and functional characteristics of the γ-globin gene promoters Blood Cells, Molecules, and Diseases. 38: 154-155. DOI: 10.1016/J.Bcmd.2006.10.083 |
0.455 |
|
2006 |
Sangerman J, Lee MS, Yao X, Oteng E, Hsiao CH, Li W, Zein S, Ofori-Acquah SF, Pace BS. Mechanism for fetal hemoglobin induction by histone deacetylase inhibitors involves gamma-globin activation by CREB1 and ATF-2. Blood. 108: 3590-9. PMID 16896160 DOI: 10.1182/Blood-2006-01-023713 |
0.493 |
|
2006 |
Pace BS, Zein S. Understanding mechanisms of gamma-globin gene regulation to develop strategies for pharmacological fetal hemoglobin induction. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 235: 1727-37. PMID 16607652 DOI: 10.1002/Dvdy.20802 |
0.508 |
|
2006 |
Hsiao CH, Li W, Lou TF, Baliga BS, Pace BS. Fetal hemoglobin induction by histone deacetylase inhibitors involves generation of reactive oxygen species. Experimental Hematology. 34: 264-73. PMID 16543060 DOI: 10.1016/J.Exphem.2005.12.009 |
0.433 |
|
2006 |
Lou T, Williams A, Li W, Pace BS. The Role of Nitric Oxide in γ-Globin Induction by Hydroxyurea. Blood. 108: 3794-3794. DOI: 10.1182/Blood.V108.11.3794.3794 |
0.438 |
|
2006 |
Li W, Pace BS. Gene Expression Profiles during the γ- to β-Globin Switch in Erythroid Progenitors. Blood. 108: 1225-1225. DOI: 10.1182/Blood.V108.11.1225.1225 |
0.571 |
|
2006 |
Yao X, Dzandu JK, Pace BS. Characterization of Combinatorial Stat3/GATA-1 Complexes in the γ-Globin 5′UTR. Blood. 108: 1223-1223. DOI: 10.1182/Blood.V108.11.1223.1223 |
0.52 |
|
2005 |
Johnson J, Hunter R, McElveen R, Qian XH, Baliga BS, Pace BS. Fetal hemoglobin induction by the histone deacetylase inhibitor, scriptaid. Cellular and Molecular Biology (Noisy-Le-Grand, France). 51: 229-38. PMID 16171558 |
0.405 |
|
2005 |
McElveen RL, Lou TF, Reese K, Xia S, Baliga BS, Pace BS. ERK pathway inhibitor U0126 induces gamma-globin expression in erythroid cells Cellular and Molecular Biology. 51: 215-227. PMID 16171557 |
0.376 |
|
2005 |
Li W, Pace BS. Gene Expression Profiles Involved in γ to β Globin Gene Switching during Erythroid Maturation. Blood. 106: 820-820. DOI: 10.1182/Blood.V106.11.820.820 |
0.466 |
|
2005 |
Lou T, Ma S, Williams A, Pace BS. Human KU812 Erythroleukemia Cells: A Model for Competitive γ-Globin Induction by Fetal Hemoglobin Inducing Drugs. Blood. 106: 2323-2323. DOI: 10.1182/Blood.V106.11.2323.2323 |
0.488 |
|
2004 |
Pace BS, Qian X, Ofori-Acquah SF. Selective inhibition of beta-globin RNA transcripts by antisense RNA molecules Cellular and Molecular Biology (Noisy-Le-Grand, France). 50: 43-51. PMID 15040426 |
0.308 |
|
2004 |
Yao X, Cubillos F, Sangerman J, Pace BS. Characterization of Stat3 Binding in the γ-Globin Promoter: The Role of DNA-Protein Interactions in Gene Silencing. Blood. 104: 503-503. DOI: 10.1182/Blood.V104.11.503.503 |
0.526 |
|
2004 |
Hsiao C, Li W, Lou T, Lee E, Pace BS. The Role of Reactive Oxygen Species in γ-Globin Gene Activation by Fetal Hemoglobin Inducers. Blood. 104: 3753-3753. DOI: 10.1182/Blood.V104.11.3753.3753 |
0.447 |
|
2004 |
Lou T, McElveen R, Xia S, Bonthu R, Baliga S, Pace B. Extracellular Regulating Kinase (ERK) Inhibition by U0126: A Novel Mechanism for γ-Globin Gene Activation. Blood. 104: 3590-3590. DOI: 10.1182/Blood.V104.11.3590.3590 |
0.564 |
|
2004 |
Lee MS, Oteng E, Sangerman J, Pace B. Gγ-Globin Promoter Trans-Activation: Characterization of Transcription Factor Interactions in the Upstream cAMP Response Element (CRE). Blood. 104: 1221-1221. DOI: 10.1182/Blood.V104.11.1221.1221 |
0.5 |
|
2003 |
Pace BS, Qian XH, Sangerman J, Ofori-Acquah SF, Baliga BS, Han J, Critz SD. p38 MAP kinase activation mediates gamma-globin gene induction in erythroid progenitors. Experimental Hematology. 31: 1089-96. PMID 14585374 DOI: 10.1016/S0301-472X(03)00235-2 |
0.441 |
|
2003 |
Pace BS, Shartava A, Pack-Mabien A, Mulekar M, Ardia A, Goodman SR. Effects of N-acetylcysteine on dense cell formation in sickle cell disease. American Journal of Hematology. 73: 26-32. PMID 12701116 DOI: 10.1002/Ajh.10321 |
0.342 |
|
2002 |
Pace BS, White GL, Dover GJ, Boosalis MS, Faller DV, Perrine SP. Short-chain fatty acid derivatives induce fetal globin expression and erythropoiesis in vivo. Blood. 100: 4640-8. PMID 12393583 DOI: 10.1182/Blood-2002-02-0353 |
0.457 |
|
2002 |
Liu Y, Li J, Kim BO, Pace BS, He JJ. HIV-1 Tat protein-mediated transactivation of the HIV-1 long terminal repeat promoter is potentiated by a novel nuclear Tat-interacting protein of 110 kDa, Tip110. The Journal of Biological Chemistry. 277: 23854-63. PMID 11959860 DOI: 10.1074/Jbc.M200773200 |
0.393 |
|
2002 |
Foley HA, Ofori-Acquah SF, Yoshimura A, Critz S, Baliga BS, Pace BS. Stat3 beta inhibits gamma-globin gene expression in erythroid cells. The Journal of Biological Chemistry. 277: 16211-9. PMID 11856732 DOI: 10.1074/jbc.M106556200 |
0.472 |
|
2001 |
Boosalis MS, Bandyopadhyay R, Bresnick EH, Pace BS, Van DeMark K, Zhang B, Faller DV, Perrine SP. Short-chain fatty acid derivatives stimulate cell proliferation and induce STAT-5 activation. Blood. 97: 3259-67. PMID 11342457 DOI: 10.1182/Blood.V97.10.3259 |
0.416 |
|
2000 |
Pace BS, Chen YR, Thompson A, Goodman SR. Butyrate-inducible elements in the human γ-globin promoter Experimental Hematology. 28: 283-293. PMID 10720693 DOI: 10.1016/S0301-472X(99)00153-8 |
0.495 |
|
2000 |
Xu L, Ferry AE, Monteiro C, Pace BS. Beta globin gene inhibition by antisense RNA transcripts Gene Therapy. 7: 438-444. PMID 10694826 |
0.447 |
|
2000 |
Foley HA, Critz S, Pace BS. Interleukin-6 silences y gene expression via the jak/stat signal transduction pathway Blood. 96. |
0.358 |
|
1999 |
Wang G, Xu X, Pace B, Dean DA, Glazer PM, Chan P, Goodman SR, Shokolenko I. Peptide nucleic acid (PNA) binding-mediated induction of human gamma-globin gene expression. Nucleic Acids Research. 27: 2806-13. PMID 10373600 DOI: 10.1093/Nar/27.13.2806 |
0.489 |
|
1998 |
Xu L, Pace BS. Modulated human globin gene expression: Role for antisense expression vectors Cellular and Molecular Biology Letters. 3: 423-433. |
0.414 |
|
1997 |
Boosalis MS, Ikuta T, Pace BS, da Fonseca S, White GL, Faller DV, Perrine SP. Abrogation of IL-3 requirements and stimulation of hematopoietic cell proliferation in vitro and in vivo by carboxylic acids. Blood Cells, Molecules & Diseases. 23: 434-42. PMID 9454687 DOI: 10.1006/Bcmd.1997.0162 |
0.389 |
|
1997 |
Ferry AE, Baliga SB, Monteiro C, Pace BS. Globin gene silencing in primary erythroid cultures. An inhibitory role for interleukin-6 Journal of Biological Chemistry. 272: 20030-20037. PMID 9242673 DOI: 10.1074/jbc.272.32.20030 |
0.492 |
|
1996 |
Pace BS, Li Q, Stamatoyannopoulos G. In vivo search for butyrate responsive sequences using transgenic mice carrying (A)γ gene promoter mutants Blood. 88: 1079-1083. PMID 8704217 DOI: 10.1182/blood.v88.3.1079.1079 |
0.445 |
|
1994 |
Pace BS, Elford HL, Stamatoyannopoulos G. Transgenic mouse model of pharmacologic induction of fetal hemoglobin: Studies using a new ribonucleotide reductase inhibitor, Didox American Journal of Hematology. 45: 136-141. PMID 7511330 |
0.309 |
|
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