Duane C. Hassane, Ph.D. - Publications

Affiliations: 
2002 University of Kentucky, Lexington, KY 
Area:
Microbiology Biology

61 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Sugita M, Galetto R, Zong H, Ewing-Crystal N, Trujillo-Alonso V, Mencia-Trinchant N, Yip W, Filipe S, Lebuhotel C, Gouble A, Hassane DC, Smith J, Roboz GJ, Guzman ML. Allogeneic TCRαβ deficient CAR T-cells targeting CD123 in acute myeloid leukemia. Nature Communications. 13: 2227. PMID 35484102 DOI: 10.1038/s41467-022-29668-9  0.339
2021 Balandrán JC, Dávila-Velderrain J, Sandoval-Cabrera A, Zamora-Herrera G, Terán-Cerqueda V, García-Stivalet LA, Limón-Flores JA, Armenta-Castro E, Rodríguez-Martínez A, Leon-Chavez BA, Vallejo-Ruiz V, Hassane DC, Pérez-Tapia SM, Ortiz-Navarrete V, Guzman ML, et al. Patient-Derived Bone Marrow Spheroids Reveal Leukemia-Initiating Cells Supported by Mesenchymal Hypoxic Niches in Pediatric B-ALL. Frontiers in Immunology. 12: 746492. PMID 34737747 DOI: 10.3389/fimmu.2021.746492  0.32
2021 Sugita M, Wilkes DC, Bareja R, Eng KW, Nataraj S, Jimenez-Flores RA, Yan L, De Leon JP, Croyle JA, Kaner J, Merugu S, Sharma S, MacDonald TY, Noorzad Z, Panchal P, ... ... Hassane DC, et al. Targeting the epichaperome as an effective precision medicine approach in a novel PML-SYK fusion acute myeloid leukemia. Npj Precision Oncology. 5: 44. PMID 34040147 DOI: 10.1038/s41698-021-00183-2  0.304
2019 Bystrom LM, Bezerra DP, Hsu HT, Zong H, Lara-Martínez LA, De Leon JP, Emmanuel M, Méry D, Gardenghi S, Hassane D, Neto CC, Cunningham-Rundles S, Becker MW, Rivella S, Guzman ML. Cranberry A-type proanthocyanidins selectively target acute myeloid leukemia cells. Blood Advances. 3: 3261-3265. PMID 31698457 DOI: 10.1182/Bloodadvances.2018026633  0.463
2019 Desai P, Hassane D, Roboz GJ. Clonal Hematopoiesis and risk of Acute Myeloid Leukemia. Best Practice & Research. Clinical Haematology. 32: 177-185. PMID 31203999 DOI: 10.1016/J.Beha.2019.05.007  0.343
2018 Roboz GJ, Mandrekar SJ, Desai P, Laumann K, Walker AR, Wang ES, Kolitz JE, Powell BL, Attar EC, Stock W, Bloomfield CD, Kohlschmidt J, Mrózek K, Hassane DC, Garraway L, et al. Randomized trial of 10 days of decitabine ± bortezomib in untreated older patients with AML: CALGB 11002 (Alliance). Blood Advances. 2: 3608-3617. PMID 30567725 DOI: 10.1182/Bloodadvances.2018023689  0.326
2018 Desai P, Mencia-Trinchant N, Savenkov O, Simon MS, Cheang G, Lee S, Samuel M, Ritchie EK, Guzman ML, Ballman KV, Roboz GJ, Hassane DC. Somatic mutations precede acute myeloid leukemia years before diagnosis. Nature Medicine. 24: 1015-1023. PMID 29988143 DOI: 10.1038/S41591-018-0081-Z  0.349
2018 Roboz GJ, Ritchie EK, Dault Y, Lam L, Marshall DC, Cruz NM, Hsu HC, Hassane DC, Christos PJ, Ippoliti C, Scandura JM, Guzman ML. Phase I trial of plerixafor combined with decitabine in newly diagnosed older patients with acute myeloid leukemia. Haematologica. PMID 29724902 DOI: 10.3324/Haematol.2017.183418  0.39
2018 Roboz GJ, Sugita M, Mosquera JM, Wilkes DC, Nataraj S, Jimenez-Flores RA, Bareja R, Yan L, Eng KW, Croyle JA, MacDonald TY, Noorzad Z, Pancirer D, Cheng S, Xiang JZ, ... ... Hassane DC, et al. Targeting the Epichaperome As an Effective Precision Medicine Approach in a Novel PML-SYK Fusion Acute Myeloid Leukemia Blood. 132: 1435-1435. DOI: 10.1182/Blood-2018-99-118764  0.444
2018 Kaner JD, Mencia-Trinchant N, Schaap A, Roboz GJ, Lee S, Desai P, Samuel M, Krichevsky S, Udoyen I, Hassane DC, Guzman ML, Ritchie EK. Acute Myeloid Leukemia (AML) with Somatic Mutations in PTPN11 Is Associated with Treatment Resistance and Poor Overall Survival Blood. 132: 2760-2760. DOI: 10.1182/Blood-2018-99-110319  0.344
2018 Sugita M, Mencia-Trinchant N, Ewing-Crystal N, Suppa G, Galetto R, Gouble A, Smith J, Roboz GJ, Hassane DC, Guzman ML. Abstract 5681: Prediction of immunotherapy outcome by multimodal assessment of minimal residual disease and persistence of allogeneic anti-CD123 CAR T-cells (UCART123) in pre-clinical models of acute myeloid leukemia Cancer Research. 78: 5681-5681. DOI: 10.1158/1538-7445.Am2018-5681  0.407
2017 Poran A, Nötzel C, Aly O, Mencia-Trinchant N, Harris CT, Guzman ML, Hassane DC, Elemento O, Kafsack BFC. Single-cell RNA sequencing reveals a signature of sexual commitment in malaria parasites. Nature. 551: 95-99. PMID 29094698 DOI: 10.1038/Nature24280  0.313
2017 Margolskee E, Hasserjian RP, Hassane D, Tam W, Mathew S, Ok CY, Wang SA, Oak J, Arber DA, Orazi A. Myelodysplastic Syndrome, Unclassifiable (MDS-U) With 1% Blasts Is a Distinct Subgroup of MDS-U With a Poor Prognosis. American Journal of Clinical Pathology. 148: 49-57. PMID 28927162 DOI: 10.1093/Ajcp/Aqx043  0.311
2017 Allan JN, Roboz GJ, Askin G, Ritchie E, Scandura J, Christos P, Hassane DC, Guzman ML. CD25 expression and outcomes in older patients with acute myelogenous leukemia treated with plerixafor and decitabine. Leukemia & Lymphoma. 1-8. PMID 28718760 DOI: 10.1080/10428194.2017.1352089  0.305
2017 Geyer JT, Tam W, Liu YC, Chen Z, Wang SA, Bueso-Ramos C, Oak J, Arber DA, Hsi E, Rogers HJ, Levinson K, Bagg A, Hassane DC, Hasserjian RP, Orazi A. Oligomonocytic chronic myelomonocytic leukemia (chronic myelomonocytic leukemia without absolute monocytosis) displays a similar clinicopathologic and mutational profile to classical chronic myelomonocytic leukemia. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 28548124 DOI: 10.1038/Modpathol.2017.45  0.327
2017 Mencia-Trinchant N, Hu Y, Alas MA, Ali F, Wouters BJ, Lee S, Ritchie EK, Desai P, Guzman ML, Roboz GJ, Hassane DC. Minimal Residual Disease Monitoring of Acute Myeloid Leukemia by Massively Multiplex Digital PCR in Patients with NPM1 Mutations. The Journal of Molecular Diagnostics : Jmd. PMID 28525762 DOI: 10.1016/J.Jmoldx.2017.03.005  0.363
2017 Nayar U, Sadek J, Reichel J, Hernandez-Hopkins D, Akar G, Barelli PJ, Sahai MA, Zhou H, Totonchy J, Jayabalan D, Niesvizky R, Guasparri I, Hassane D, Liu Y, Sei S, et al. Identification of a nucleoside analog active against adenosine kinase-expressing plasma cell malignancies. The Journal of Clinical Investigation. PMID 28504647 DOI: 10.1172/Jci83936  0.436
2017 Cruz NM, Mencia-Trinchant N, Hassane DC, Guzman ML. Minimal residual disease in acute myelogenous leukemia. International Journal of Laboratory Hematology. 39: 53-60. PMID 28447422 DOI: 10.1111/Ijlh.12670  0.365
2017 Glass J, Hassane DC, Wouters B, Kunimoto H, Avellino R, Garrett-Bakelman FE, Guryanova OA, Bowman R, Redlich S, Intlekofer A, Meydan C, Qin T, Fall MP, Alonso A, Guzman ML, et al. Epigenetic Identity in AML Depends on Disruption of Non-promoter Regulatory Elements and is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers. Cancer Discovery. PMID 28408400 DOI: 10.1158/2159-8290.Cd-16-1032  0.334
2017 Desai P, Mencia-Trinchant N, Oleksandr S, Simon MS, Lee S, Ritchie EK, Guzman ML, Ballman K, Roboz GJ, Hassane DC. Acute Myeloid Leukemia (AML) Patients Demonstrate Increased Prevalence of AML-Defining Mutations in Peripheral Blood Years Prior to the Development of Overt Leukemia: A Case-Control Study Blood. 130: 408-408. DOI: 10.1182/Blood.V130.Suppl_1.408.408  0.348
2016 Li S, Garrett-Bakelman FE, Chung SS, Sanders MA, Hricik T, Rapaport F, Patel J, Dillon R, Vijay P, Brown AL, Perl AE, Cannon J, Bullinger L, Luger S, Becker M, ... ... Hassane DC, et al. Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia. Nature Medicine. PMID 27322744 DOI: 10.1038/Nm.4125  0.371
2016 Silver RT, Barel A, Lascu E, Ritchie EK, Roboz GJ, Christos P, Orazi A, Hassane DC, Tam W, Cross NCP. The Effect of Initial Molecular Profile on Response to Recombinant Interferon Alpha (rIFNα) Treatment in Early Myelofibrosis Blood. 128: 944-944. DOI: 10.1182/Blood.V128.22.944.944  0.323
2016 Guzman ML, Sugita M, Zong H, Ewing-Crystal N, Trujillo-Alonso V, Mencia-Trinchant N, Lam L, Cruz NM, Galetto R, Gouble A, Hassane DC, Smith J, Roboz GJ. Allogeneic Tcrα/β Deficient CAR T-Cells Targeting CD123 Prolong Overall Survival of AML Patient-Derived Xenografts Blood. 128: 765-765. DOI: 10.1182/Blood.V128.22.765.765  0.451
2016 Lee S, Barnard J, DeZern AE, Maciejewski JP, Alali N, Steensma DP, Ritchie EK, Desai P, Garcia-Manero G, Ali F, Rizzo N, Hassane DC, Komrokji RS, Sekeres MA, Roboz GJ. Is Serial Monitoring of Myeloid Mutations Clinically Relevant in Myelodysplastic Syndromes (MDS): A Report on Behalf of the MDS Clinical Research Consortium (CRC) Blood. 128: 297-297. DOI: 10.1182/Blood.V128.22.297.297  0.344
2016 Mencia-Trinchant N, Youssef A, Hu Y, Ali F, Ritchie EK, Guzman ML, Roboz GJ, Hassane DC. Minimal Residual Disease Assessment of Common and Rare NPM1 Mutations Using a Single Massively Multiplex Digital PCR Assay Blood. 128: 2888-2888. DOI: 10.1182/Blood.V128.22.2888.2888  0.36
2016 Li S, Garrett-Bakelman FE, Chung SS, Hricik T, Rapaport F, Patel J, Dillon R, Vijay P, Brown AL, Perl AE, Connon J, Sanders MA, Valk PJM, Bullinger L, Luger S, ... ... Hassane DC, et al. Abstract LB-073: Epigenome evolution in relapsed acute myeloid leukemia Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-073  0.316
2015 Garrett-Bakelman FE, Li S, Chung SS, Hricik T, Franck R, Patel J, Dillon R, Vijay P, Brown AL, Perl AE, Cannon BJ, Sanders MA, Valk PJM, Bullinger L, Luger S, ... ... Hassane DC, et al. Divergent Dynamics of Epigenetic and Genetic Heterogeneity in Relapsed Acute Myeloid Leukemia Blood. 126: 306-306. DOI: 10.1182/Blood.V126.23.306.306  0.398
2014 Guzman ML, Yang N, Sharma KK, Balys M, Corbett CA, Jordan CT, Becker MW, Steidl U, Abdel-Wahab O, Levine RL, Marcucci G, Roboz GJ, Hassane DC. Selective activity of the histone deacetylase inhibitor AR-42 against leukemia stem cells: a novel potential strategy in acute myelogenous leukemia. Molecular Cancer Therapeutics. 13: 1979-90. PMID 24934933 DOI: 10.1158/1535-7163.Mct-13-0963  0.435
2014 Mencia-Trinchant N, Roboz GJ, Carroll MP, Guzman ML, Hassane DC. Ultra-Deep Sequencing Defines Stem Cell-Specific Diversity Patterns in Acute Myelogenous Leukemia Blood. 124: 4790-4790. DOI: 10.1182/Blood.V124.21.4790.4790  0.434
2014 Allan JN, Jayabalan D, Niesvizky R, Mark TM, Pearse R, Rossi AC, Tegnestam L, Hassane DC, Guzman ML. Proteasome Inhibitor Treatment in Multiple Myeloma Can Mobilize Hematopoietic Stem Cells in the Absence of G-CSF Blood. 124: 2452-2452. DOI: 10.1182/Blood.V124.21.2452.2452  0.32
2014 Allan JN, Roboz GJ, Feldman EJ, Scandura JM, Ritchie EK, Lam L, Xie W, Hsu H, Hassane DC, Guzman ML. Interleukin 2 Receptor-α (CD25) Expression Is Associated with Shortened Overall Survival and Resistance to Induction Therapy with Plerixafor and Decitabine in Older Patients with Newly Diagnosed Acute Myeloid Leukemia (AML) Blood. 124: 1041-1041. DOI: 10.1182/Blood.V124.21.1041.1041  0.301
2014 Kita K, Tran A, Brown LM, Hassane DC, Carey S, Matov A, Reinhart-King CA, Giannakakou P. Abstract 1158: Microtubule perturbation regulates remodeling of tumor microenvironment by modulating the composition of tumor cell secretome Cancer Research. 74: 1158-1158. DOI: 10.1158/1538-7445.Am2014-1158  0.376
2013 Sen S, Hassane DC, Corbett C, Becker MW, Jordan CT, Guzman ML. Novel mTOR inhibitory activity of ciclopirox enhances parthenolide antileukemia activity. Experimental Hematology. 41: 799-807.e4. PMID 23660068 DOI: 10.1016/J.Exphem.2013.04.012  0.338
2013 Sampson ER, McMurray HR, Hassane DC, Newman L, Salzman P, Jordan CT, Land H. Gene signature critical to cancer phenotype as a paradigm for anticancer drug discovery. Oncogene. 32: 3809-18. PMID 22964631 DOI: 10.1038/Onc.2012.389  0.341
2013 Felipe Rico J, Hassane DC, Guzman ML. Acute myelogenous leukemia stem cells: from Bench to Bedside. Cancer Letters. 338: 4-9. PMID 22713929 DOI: 10.1016/J.Canlet.2012.05.034  0.43
2013 Galletti G, Cleveland K, Matov A, Hayes JE, Klein RJ, Hassane DC, Nicacio LV, Giannakakou P, Shah MA. Clinical and preclinical evaluation of taxane sensitivity in gastric cancer (GC): Relevance of GC histology. Journal of Clinical Oncology. 31: 37-37. DOI: 10.1200/Jco.2013.31.4_Suppl.37  0.307
2013 Tran A, Kita K, Matov A, Hassane DC, Brown LM, Giannakakou P. Abstract 5162: Microtubule stabilization alters tumor secretome and fibroblast activation. Cancer Research. 73: 5162-5162. DOI: 10.1158/1538-7445.Am2013-5162  0.372
2013 Carbonaro M, Hassane D, Giannakakou P. Abstract 2318: The microtubule cytoskeleton in the dynamic regulation of translation: implications for taxane therapy. Cancer Research. 73: 2318-2318. DOI: 10.1158/1538-7445.Am2013-2318  0.334
2012 Ashton JM, Balys M, Neering SJ, Hassane DC, Cowley G, Root DE, Miller PG, Ebert BL, McMurray HR, Land H, Jordan CT. Gene sets identified with oncogene cooperativity analysis regulate in vivo growth and survival of leukemia stem cells. Cell Stem Cell. 11: 359-72. PMID 22863534 DOI: 10.1016/J.Stem.2012.05.024  0.424
2012 Guasparri I, Hassane DC, Roshal M, Cesarman E. The Viral Oncoprotein vFLIP Encoded by KSHV/HHV-8 Is Responsible for the Unique Transcriptional Signature and Phenotypic Features of Primary Effusion Lymphoma Blood. 120: 900-900. DOI: 10.1182/Blood.V120.21.900.900  0.401
2012 Bystrom L, Hsu H, Neto C, Roboz GJ, Hassane DC, Rivella S, Guzman ML. A-Type Proanthocyanidins From Cranberries Target Acute Myelogenous Leukemia Stem Cells. Blood. 120: 2986-2986. DOI: 10.1182/Blood.V120.21.2986.2986  0.453
2012 Tran AD, Brown LM, Hassane DC, Giannakakou P. Abstract 1502: Microtubule stabilization alters tumor secretome and fibroblast activation Cancer Research. 72: 1502-1502. DOI: 10.1158/1538-7445.Am2012-1502  0.371
2011 Ashton JM, Balys M, Neering S, Cowley G, Root DE, Miller PG, Ebert B, McMurray H, Hassane DC, Land H, Jordan CT. Oncogene Cooperativity Analysis Reveals a Novel Set of Genes That Regulate the In Vivo Growth and Survival of Leukemia Stem Cells Blood. 118: 553-553. DOI: 10.1182/Blood.V118.21.553.553  0.449
2011 Hassane DC, Leon JPD, Corbett C, Rossi RM, Xie W, Jordan CT, Guzman ML. Troglitazone and Prochloroperazine Repositioned As An Anti-Leukemia Stem Cell Drug Combination Using Chemical Genomics-Based Prediction Blood. 118: 1885-1885. DOI: 10.1182/Blood.V118.21.1885.1885  0.359
2011 Xie W, Hassane DC, Jordan CT, Roboz GJ, Guzman ML. High Throughput Screening Reveals Unique Sensitivity of CD34+CD38- AML Cells to Isotretinoin and Tretinoin Blood. 118: 1430-1430. DOI: 10.1182/Blood.V118.21.1430.1430  0.371
2011 Sharma KK, Rico JF, Hassane DC, Chiosis G, Guzman ML. Dysregulated Expression of HSP70 Isoforms in Acute Myelogenous Leukemia (AML) Blood. 118: 1370-1370. DOI: 10.1182/Blood.V118.21.1370.1370  0.393
2011 Yang N, Hassane DC, Balys M, Corbett CA, Jordan CT, Guzman ML. Abstract 2145: AR-42, a novel histone deacetylase inhibitor with selectivity against leukemia stem cell via apoptosis induction, inhibition of chaperone function of heat shock protein 90 in acute myeloid leukemia Cancer Research. 71: 2145-2145. DOI: 10.1158/1538-7445.Am2011-2145  0.43
2010 Hassane DC, Sen S, Minhajuddin M, Rossi RM, Corbett CA, Balys M, Wei L, Crooks PA, Guzman ML, Jordan CT. Chemical genomic screening reveals synergism between parthenolide and inhibitors of the PI-3 kinase and mTOR pathways. Blood. 116: 5983-90. PMID 20889920 DOI: 10.1182/Blood-2010-04-278044  0.397
2009 Hassane D, Sen S, Corbett CA, Balys M, Rossi RM, Crooks PA, Guzman ML, Jordan CT. Chemical Genomic Screening Reveals That PI3K/mTOR Inhibition Enhances Activity of the Anti-Leukemia Stem Cell Compound Parthenolide. Blood. 114: 388-388. DOI: 10.1182/Blood.V114.22.388.388  0.455
2009 Ashton JM, Hassane D, Neering S, Bushnell TP, Jordan CT. Synergistically Regulated Genes and Pathways in Leukemias Induced by Co-Expression of BCR-ABL and Nup98-HoxA9. Blood. 114: 3473-3473. DOI: 10.1182/Blood.V114.22.3473.3473  0.464
2009 Hassane D, Balys M, Marcucci G, Byrd JC, Jordan CT, Guzman ML. Identification of the Histone Deacetylase Inhibitor (HDACi), AR-42, as a Novel Anti-Leukemia Stem Cell Agent in Acute Myeloid Leukemia (AML). Blood. 114: 2070-2070. DOI: 10.1182/Blood.V114.22.2070.2070  0.44
2008 Hassane DC, Guzman ML, Corbett C, Li X, Abboud R, Young F, Liesveld JL, Carroll M, Jordan CT. Discovery of agents that eradicate leukemia stem cells using an in silico screen of public gene expression data. Blood. 111: 5654-62. PMID 18305216 DOI: 10.1182/Blood-2007-11-126003  0.435
2008 Hassane DC, Ashton JM, Guzman ML, Jordan CT. Genes Dysregulated in a Murine Model of Leukemogenesis Comprise a Signature for Identification of Therapeutics in Humans. Blood. 112: 3349-3349. DOI: 10.1182/Blood.V112.11.3349.3349  0.342
2007 Guzman ML, Rossi RM, Neelakantan S, Li X, Corbett CA, Hassane DC, Becker MW, Bennett JM, Sullivan E, Lachowicz JL, Vaughan A, Sweeney CJ, Matthews W, Carroll M, Liesveld JL, et al. An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells. Blood. 110: 4427-35. PMID 17804695 DOI: 10.1182/Blood-2007-05-090621  0.435
2007 Hassane DC, Guzman ML, Corbett C, Li X, Liesveld JL, Young F, Carroll M, Jordan CT. A Search of Public Gene Expression Microarray Data Identifies Novel Agents That Selectively Eradicate AML Stem Cells. Blood. 110: 776-776. DOI: 10.1182/Blood.V110.11.776.776  0.437
2006 Hassane DC, Guzman ML, Li X, Corbett C, Jordan CT. Molecular Signature for Parthenolide-Induced Apoptosis in AML CD34+ Cells Reveals Targets for Improving Induction of Leukemia-Specific Cell Death. Blood. 108: 2592-2592. DOI: 10.1182/Blood.V108.11.2592.2592  0.433
2006 Guzman ML, Rossi RM, Li X, Corbett C, Hassane DC, Bushnell T, Carroll M, Sullivan E, Neelakantan S, Crooks PA, Jordan CT. A Novel Orally Available Parthenolide Analog Selectively Eradicates AML Stem and Progenitor Cells. Blood. 108: 237-237. DOI: 10.1182/Blood.V108.11.237.237  0.451
2005 Guzman ML, Li X, Corbett C, Hassane DC, Jordan CT. Mechanisms Controlling Selective Death of Leukemia Stem Cells in Response to Parthenolide. Blood. 106: 467-467. DOI: 10.1182/Blood.V106.11.467.467  0.443
2003 Lee RB, Hassane DC, Cottle DL, Pickett CL. Interactions of Campylobacter jejuni cytolethal distending toxin subunits CdtA and CdtC with HeLa cells. Infection and Immunity. 71: 4883-90. PMID 12933829 DOI: 10.1128/Iai.71.9.4883-4890.2003  0.582
2003 Hassane DC, Lee RB, Pickett CL. Campylobacter jejuni cytolethal distending toxin promotes DNA repair responses in normal human cells. Infection and Immunity. 71: 541-5. PMID 12496208 DOI: 10.1128/Iai.71.1.541-545.2003  0.574
2001 Hassane DC, Lee RB, Mendenhall MD, Pickett CL. Cytolethal distending toxin demonstrates genotoxic activity in a yeast model. Infection and Immunity. 69: 5752-9. PMID 11500452 DOI: 10.1128/Iai.69.9.5752-5759.2001  0.603
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