William C. Gause - Publications

Affiliations: 
Uniformed Services University of the Health Sciences, Bethesda, MD 
Area:
Molecular Biology, Immunology, Microbiology Biology

115 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Maizels RM, Gause WC. Targeting helminths: The expanding world of type 2 immune effector mechanisms. The Journal of Experimental Medicine. 220. PMID 37638887 DOI: 10.1084/jem.20221381  0.334
2022 Rovira-Diaz E, El-Naccache DW, Reyes J, Zhao Y, Nasuhidehnavi A, Chen F, Gause WC, Yap GS. The Impact of Helminth Coinfection on Innate and Adaptive Immune Resistance and Disease Tolerance during Toxoplasmosis. Journal of Immunology (Baltimore, Md. : 1950). 209: 2160-2171. PMID 36426972 DOI: 10.4049/jimmunol.2200504  0.424
2022 Rovira-Diaz E, El-Naccache DW, Reyes J, Zhao Y, Nasuhidehnavi A, Chen F, Gause WC, Yap GS. The Impact of Helminth Coinfection on Innate and Adaptive Immune Resistance and Disease Tolerance during Toxoplasmosis. Journal of Immunology (Baltimore, Md. : 1950). PMID 36253053 DOI: 10.4049/jimmunol.2200504  0.43
2022 Valero-Pacheco N, Tang EK, Massri N, Loia R, Chemerinski A, Wu T, Begum S, El-Naccache DW, Gause WC, Arora R, Douglas NC, Beaulieu AM. Maternal IL-33 critically regulates tissue remodeling and type 2 immune responses in the uterus during early pregnancy in mice. Proceedings of the National Academy of Sciences of the United States of America. 119: e2123267119. PMID 35994660 DOI: 10.1073/pnas.2123267119  0.409
2022 El-Naccache DW, Chen F, Palma MJ, Lemenze A, Fischer MA, Wu W, Mishra PK, Eltzschig HK, Robson SC, Di Virgilio F, Yap GS, Edelblum KL, Haskó G, Gause WC. Adenosine metabolized from extracellular ATP promotes type 2 immunity through triggering AAR signaling in intestinal epithelial cells. Cell Reports. 40: 111150. PMID 35926464 DOI: 10.1016/j.celrep.2022.111150  0.396
2021 Lothstein KE, Gause WC. Mining Helminths for Novel Therapeutics. Trends in Molecular Medicine. PMID 33495068 DOI: 10.1016/j.molmed.2020.12.010  0.315
2020 El-Naccache DW, Haskó G, Gause WC. Early Events Triggering the Initiation of a Type 2 Immune Response. Trends in Immunology. PMID 33386241 DOI: 10.1016/j.it.2020.11.006  0.374
2020 Gause WC, Rothlin C, Loke P. Heterogeneity in the initiation, development and function of type 2 immunity. Nature Reviews. Immunology. PMID 32367051 DOI: 10.1038/S41577-020-0301-X  0.453
2020 El-Naccache DW, Chen F, Chen N, Gause WC. The NET Effect of Neutrophils during Helminth Infection. Cell Host & Microbe. 27: 165-168. PMID 32053785 DOI: 10.1016/J.Chom.2020.01.013  0.357
2019 Mishra PK, Palma M, Buechel B, Moore J, Davra V, Chu N, Millman A, Hallab NJ, Kanneganti TD, Birge RB, Behrens EM, Rivera A, Beebe KS, Benevenia J, Gause WC. Sterile particle-induced inflammation is mediated by macrophages releasing IL-33 through a Bruton's tyrosine kinase-dependent pathway. Nature Materials. PMID 30664693 DOI: 10.1038/S41563-018-0271-6  0.532
2018 Chen F, Wu W, Jin L, Millman A, Palma M, El-Naccache DW, Lothstein KE, Dong C, Edelblum KL, Gause WC. B Cells Produce the Tissue-Protective Protein RELMα during Helminth Infection, which Inhibits IL-17 Expression and Limits Emphysema. Cell Reports. 25: 2775-2783.e3. PMID 30517865 DOI: 10.1016/J.Celrep.2018.11.038  0.528
2018 Yap GS, Gause WC. Helminth Infections Induce Tissue Tolerance Mitigating Immunopathology but Enhancing Microbial Pathogen Susceptibility. Frontiers in Immunology. 9: 2135. PMID 30386324 DOI: 10.3389/Fimmu.2018.02135  0.459
2017 Marple A, Wu W, Shah S, Zhao Y, Du P, Gause WC, Yap GS. Correction: Cutting Edge: Helminth Coinfection Blocks Effector Differentiation of CD8 T Cells through Alternate Host Th2- and IL-10-Mediated Responses. Journal of Immunology (Baltimore, Md. : 1950). 199: 3005. PMID 29018152 DOI: 10.4049/jimmunol.1701193  0.508
2016 Marple A, Wu W, Shah S, Zhao Y, Du P, Gause WC, Yap GS. Cutting Edge: Helminth Coinfection Blocks Effector Differentiation of CD8 T Cells through Alternate Host Th2- and IL-10-Mediated Responses. Journal of Immunology (Baltimore, Md. : 1950). PMID 27956529 DOI: 10.4049/Jimmunol.1601741  0.573
2016 Gause WC, Maizels RM. Macrobiota - helminths as active participants and partners of the microbiota in host intestinal homeostasis. Current Opinion in Microbiology. 32: 14-18. PMID 27116368 DOI: 10.1016/J.Mib.2016.04.004  0.422
2016 Ramanan D, Bowcutt R, Lee SC, Tang MS, Kurtz ZD, Ding Y, Honda K, Gause WC, Blaser MJ, Bonneau RA, Lim YA, Loke P, Cadwell K. Helminth infection promotes colonization resistance via type 2 immunity. Science (New York, N.Y.). PMID 27080105 DOI: 10.1126/Science.Aaf3229  0.367
2016 Rivera A, Siracusa MC, Yap GS, Gause WC. Innate cell communication kick-starts pathogen-specific immunity. Nature Immunology. 17: 356-63. PMID 27002843 DOI: 10.1038/Ni.3375  0.477
2015 Zaiss DM, Gause WC, Osborne LC, Artis D. Emerging functions of amphiregulin in orchestrating immunity, inflammation, and tissue repair. Immunity. 42: 216-26. PMID 25692699 DOI: 10.1016/J.Immuni.2015.01.020  0.41
2015 Rafi W, Bhatt K, Gause WC, Salgame P. Neither primary nor memory immunity to Mycobacterium tuberculosis infection is compromised in mice with chronic enteric helminth infection. Infection and Immunity. 83: 1217-23. PMID 25605766 DOI: 10.1128/Iai.03004-14  0.436
2014 Gause WC, Wilson MS. Immunity to parasitic infections at mucous-protected environmental interfaces. Parasite Immunology. 36: 397-9. PMID 25201403 DOI: 10.1111/Pim.12131  0.385
2014 Chen F, Wu W, Millman A, Craft JF, Chen E, Patel N, Boucher JL, Urban JF, Kim CC, Gause WC. Neutrophils prime a long-lived effector macrophage phenotype that mediates accelerated helminth expulsion. Nature Immunology. 15: 938-46. PMID 25173346 DOI: 10.1038/Ni.2984  0.333
2014 Mishra PK, Palma M, Bleich D, Loke P, Gause WC. Systemic impact of intestinal helminth infections. Mucosal Immunology. 7: 753-62. PMID 24736234 DOI: 10.1038/Mi.2014.23  0.463
2014 Patel N, Wu W, Mishra PK, Chen F, Millman A, Csóka B, Koscsó B, Eltzschig HK, Haskó G, Gause WC. A2B adenosine receptor induces protective antihelminth type 2 immune responses. Cell Host & Microbe. 15: 339-50. PMID 24629340 DOI: 10.1016/J.Chom.2014.02.001  0.628
2013 Esser-von Bieren J, Mosconi I, Guiet R, Piersgilli A, Volpe B, Chen F, Gause WC, Seitz A, Verbeek JS, Harris NL. Antibodies trap tissue migrating helminth larvae and prevent tissue damage by driving IL-4Rα-independent alternative differentiation of macrophages. Plos Pathogens. 9: e1003771. PMID 24244174 DOI: 10.1371/Journal.Ppat.1003771  0.444
2013 Salgame P, Yap GS, Gause WC. Effect of helminth-induced immunity on infections with microbial pathogens. Nature Immunology. 14: 1118-26. PMID 24145791 DOI: 10.1038/Ni.2736  0.446
2013 Gause WC, Wynn TA, Allen JE. Type 2 immunity and wound healing: evolutionary refinement of adaptive immunity by helminths. Nature Reviews. Immunology. 13: 607-14. PMID 23827958 DOI: 10.1038/Nri3476  0.419
2013 Mishra PK, Patel N, Wu W, Bleich D, Gause WC. Prevention of type 1 diabetes through infection with an intestinal nematode parasite requires IL-10 in the absence of a Th2-type response Mucosal Immunology. 6: 297-308. PMID 22806101 DOI: 10.1038/Mi.2012.71  0.578
2012 Chen F, Liu Z, Wu W, Rozo C, Bowdridge S, Millman A, Van Rooijen N, Urban JF, Wynn TA, Gause WC. An essential role for TH2-type responses in limiting acute tissue damage during experimental helminth infection. Nature Medicine. 18: 260-6. PMID 22245779 DOI: 10.1038/Nm.2628  0.438
2012 Csóka B, Selmeczy Z, Koscsó B, Németh ZH, Pacher P, Murray PJ, Kepka-Lenhart D, Morris SM, Gause WC, Leibovich SJ, Haskó G. Adenosine promotes alternative macrophage activation via A2A and A2B receptors. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 376-86. PMID 21926236 DOI: 10.1096/Fj.11-190934  0.435
2011 Mishra PK, Wu W, Rozo C, Hallab NJ, Benevenia J, Gause WC. Micrometer-sized titanium particles can induce potent Th2-type responses through TLR4-independent pathways. Journal of Immunology (Baltimore, Md. : 1950). 187: 6491-8. PMID 22095717 DOI: 10.4049/Jimmunol.1101392  0.543
2011 Potian JA, Rafi W, Bhatt K, McBride A, Gause WC, Salgame P. Preexisting helminth infection induces inhibition of innate pulmonary anti-tuberculosis defense by engaging the IL-4 receptor pathway. The Journal of Experimental Medicine. 208: 1863-74. PMID 21825018 DOI: 10.1084/Jem.20091473  0.527
2011 Harris N, Gause WC. To B or not to B: B cells and the Th2-type immune response to helminths. Trends in Immunology. 32: 80-8. PMID 21159556 DOI: 10.1016/J.It.2010.11.005  0.548
2010 Bowdridge S, Gause WC. Regulation of alternative macrophage activation by chromatin remodeling. Nature Immunology. 11: 879-81. PMID 20856215 DOI: 10.1038/Ni1010-879  0.309
2010 Liu Q, Kreider T, Bowdridge S, Liu Z, Song Y, Gaydo AG, Urban JF, Gause WC. B cells have distinct roles in host protection against different nematode parasites. Journal of Immunology (Baltimore, Md. : 1950). 184: 5213-23. PMID 20357259 DOI: 10.4049/Jimmunol.0902879  0.526
2010 Liu Z, Liu Q, Bleich D, Salgame P, Gause WC. Regulation of type 1 diabetes, tuberculosis, and asthma by parasites. Journal of Molecular Medicine (Berlin, Germany). 88: 27-38. PMID 19844667 DOI: 10.1007/S00109-009-0546-0  0.402
2009 Liu Q, Sundar K, Mishra PK, Mousavi G, Liu Z, Gaydo A, Alem F, Lagunoff D, Bleich D, Gause WC. Helminth infection can reduce insulitis and type 1 diabetes through CD25- and IL-10-independent mechanisms. Infection and Immunity. 77: 5347-58. PMID 19752032 DOI: 10.1128/Iai.01170-08  0.523
2009 Patel N, Kreider T, Urban JF, Gause WC. Characterisation of effector mechanisms at the host:parasite interface during the immune response to tissue-dwelling intestinal nematode parasites. International Journal For Parasitology. 39: 13-21. PMID 18804113 DOI: 10.1016/J.Ijpara.2008.08.003  0.539
2008 Zhao A, Urban JF, Anthony RM, Sun R, Stiltz J, van Rooijen N, Wynn TA, Gause WC, Shea-Donohue T. Th2 cytokine-induced alterations in intestinal smooth muscle function depend on alternatively activated macrophages. Gastroenterology. 135: 217-225.e1. PMID 18471439 DOI: 10.1053/J.Gastro.2008.03.077  0.497
2008 Pesce JT, Liu Z, Hamed H, Alem F, Whitmire J, Lin H, Liu Q, Urban JF, Gause WC. Neutrophils clear bacteria associated with parasitic nematodes augmenting the development of an effective Th2-type response. Journal of Immunology (Baltimore, Md. : 1950). 180: 464-74. PMID 18097048 DOI: 10.4049/Jimmunol.180.1.464  0.755
2007 Anthony RM, Rutitzky LI, Urban JF, Stadecker MJ, Gause WC. Protective immune mechanisms in helminth infection. Nature Reviews. Immunology. 7: 975-87. PMID 18007680 DOI: 10.1038/Nri2199  0.467
2007 Liu Q, Liu Z, Rozo CT, Hamed HA, Alem F, Urban JF, Gause WC. The role of B cells in the development of CD4 effector T cells during a polarized Th2 immune response. Journal of Immunology (Baltimore, Md. : 1950). 179: 3821-30. PMID 17785819 DOI: 10.4049/Jimmunol.179.6.3821  0.6
2007 Kreider T, Anthony RM, Urban JF, Gause WC. Alternatively activated macrophages in helminth infections. Current Opinion in Immunology. 19: 448-53. PMID 17702561 DOI: 10.1016/J.Coi.2007.07.002  0.505
2007 Urban JF, Steenhard NR, Solano-Aguilar GI, Dawson HD, Iweala OI, Nagler CR, Noland GS, Kumar N, Anthony RM, Shea-Donohue T, Weinstock J, Gause WC. Infection with parasitic nematodes confounds vaccination efficacy. Veterinary Parasitology. 148: 14-20. PMID 17587500 DOI: 10.1016/J.Vetpar.2007.05.006  0.39
2007 Urban JF, Smith A, Botero S, Dawson H, Anthony R, Gause W, Shea-Donohue T. Selenium (Se) deficiency alters intestinal diaphorase activity in mice infected with the intestinal parasitic worm Heligmosomoides polygyrus The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A63-A  0.325
2006 Anthony RM, Urban JF, Alem F, Hamed HA, Rozo CT, Boucher JL, Van Rooijen N, Gause WC. Memory T(H)2 cells induce alternatively activated macrophages to mediate protection against nematode parasites. Nature Medicine. 12: 955-60. PMID 16892038 DOI: 10.1038/Nm1451  0.534
2006 Liu Q, Liu Z, Whitmire J, Alem F, Hamed H, Pesce J, Urban JF, Gause WC. IL-18 stimulates IL-13-mediated IFN-gamma-sensitive host resistance in vivo. European Journal of Immunology. 36: 1187-98. PMID 16568498 DOI: 10.1002/Eji.200535668  0.786
2006 Anthony RM, Gause WC. IL-4 in situ staining Nature Protocols. DOI: 10.1038/Nprot.2006.194  0.453
2005 Németh ZH, Lutz CS, Csóka B, Deitch EA, Leibovich SJ, Gause WC, Tone M, Pacher P, Vizi ES, Haskó G. Adenosine augments IL-10 production by macrophages through an A2B receptor-mediated posttranscriptional mechanism. Journal of Immunology (Baltimore, Md. : 1950). 175: 8260-70. PMID 16339566 DOI: 10.4049/Jimmunol.175.12.8260  0.453
2005 Zhao A, Morimoto M, Dawson H, Elfrey JE, Madden KB, Gause WC, Min B, Finkelman FD, Urban JF, Shea-Donohue T. Immune regulation of protease-activated receptor-1 expression in murine small intestine during Nippostrongylus brasiliensis infection. Journal of Immunology (Baltimore, Md. : 1950). 175: 2563-9. PMID 16081830 DOI: 10.4049/Jimmunol.175.4.2563  0.553
2005 Liu Z, Liu Q, Hamed H, Anthony RM, Foster A, Finkelman FD, Urban JF, Gause WC. IL-2 and autocrine IL-4 drive the in vivo development of antigen-specific Th2 T cells elicited by nematode parasites. Journal of Immunology (Baltimore, Md. : 1950). 174: 2242-9. PMID 15699158 DOI: 10.4049/Jimmunol.174.4.2242  0.604
2004 Liu Z, Liu Q, Pesce J, Anthony RM, Lamb E, Whitmire J, Hamed H, Morimoto M, Urban JF, Gause WC. Requirements for the development of IL-4-producing T cells during intestinal nematode infections: what it takes to make a Th2 cell in vivo. Immunological Reviews. 201: 57-74. PMID 15361233 DOI: 10.1111/J.0105-2896.2004.00186.X  0.798
2004 Liu Q, Arseculeratne C, Liu Z, Whitmire J, Grusby MJ, Finkelman FD, Darling TN, Cheever AW, Swearengen J, Urban JF, Gause WC. Simultaneous deficiency in CD28 and STAT6 results in chronic ectoparasite-induced inflammatory skin disease. Infection and Immunity. 72: 3706-15. PMID 15213110 DOI: 10.1128/Iai.72.7.3706-3715.2004  0.531
2004 Madden KB, Yeung KA, Zhao A, Gause WC, Finkelman FD, Katona IM, Urban JF, Shea-Donohue T. Enteric nematodes induce stereotypic STAT6-dependent alterations in intestinal epithelial cell function. Journal of Immunology (Baltimore, Md. : 1950). 172: 5616-21. PMID 15100305 DOI: 10.4049/Jimmunol.172.9.5616  0.527
2004 Morimoto M, Morimoto M, Whitmire J, Xiao S, Anthony RM, Mirakami H, Star RA, Urban JF, Gause WC. Peripheral CD4 T cells rapidly accumulate at the host: parasite interface during an inflammatory Th2 memory response. Journal of Immunology (Baltimore, Md. : 1950). 172: 2424-30. PMID 14764713 DOI: 10.4049/Jimmunol.172.4.2424  0.512
2003 Zhao A, McDermott J, Urban JF, Gause W, Madden KB, Yeung KA, Morris SC, Finkelman FD, Shea-Donohue T. Dependence of IL-4, IL-13, and nematode-induced alterations in murine small intestinal smooth muscle contractility on Stat6 and enteric nerves. Journal of Immunology (Baltimore, Md. : 1950). 171: 948-54. PMID 12847266 DOI: 10.4049/Jimmunol.171.2.948  0.514
2003 Gause WC, Urban JF, Stadecker MJ. The immune response to parasitic helminths: insights from murine models. Trends in Immunology. 24: 269-77. PMID 12738422 DOI: 10.1016/S1471-4906(03)00101-7  0.487
2003 Ekkens MJ, Liu Z, Liu Q, Whitmire J, Xiao S, Foster A, Pesce J, VanNoy J, Sharpe AH, Urban JF, Gause WC. The role of OX40 ligand interactions in the development of the Th2 response to the gastrointestinal nematode parasite Heligmosomoides polygyrus. Journal of Immunology (Baltimore, Md. : 1950). 170: 384-93. PMID 12496423 DOI: 10.4049/Jimmunol.170.1.384  0.798
2002 Liu Z, Liu Q, Pesce J, Whitmire J, Ekkens MJ, Foster A, VanNoy J, Sharpe AH, Urban JF, Gause WC. Nippostrongylus brasiliensis can induce B7-independent antigen-specific development of IL-4-producing T cells from naive CD4 T cells in vivo. Journal of Immunology (Baltimore, Md. : 1950). 169: 6959-68. PMID 12471130 DOI: 10.4049/Jimmunol.169.12.6959  0.78
2002 Madden KB, Whitman L, Sullivan C, Gause WC, Urban JF, Katona IM, Finkelman FD, Shea-Donohue T. Role of STAT6 and mast cells in IL-4- and IL-13-induced alterations in murine intestinal epithelial cell function. Journal of Immunology (Baltimore, Md. : 1950). 169: 4417-22. PMID 12370375 DOI: 10.4049/Jimmunol.169.8.4417  0.51
2002 Ekkens MJ, Liu Z, Liu Q, Foster A, Whitmire J, Pesce J, Sharpe AH, Urban JF, Gause WC. Memory Th2 effector cells can develop in the absence of B7-1/B7-2, CD28 interactions, and effector Th cells after priming with an intestinal nematode parasite. Journal of Immunology (Baltimore, Md. : 1950). 168: 6344-51. PMID 12055251 DOI: 10.4049/Jimmunol.168.12.6344  0.77
2002 Lang TJ, Nguyen P, Peach R, Gause WC, Via CS. In vivo CD86 blockade inhibits CD4+ T cell activation, whereas CD80 blockade potentiates CD8+ T cell activation and CTL effector function. Journal of Immunology (Baltimore, Md. : 1950). 168: 3786-92. PMID 11937530 DOI: 10.4049/Jimmunol.168.8.3786  0.409
2001 Jankovic D, Liu Z, Gause WC. Th1- and Th2-cell commitment during infectious disease: Asymmetry in divergent pathways Trends in Immunology. 22: 450-457. PMID 11473835 DOI: 10.1016/S1471-4906(01)01975-5  0.515
2001 Snapper CM, Shen Y, Khan AQ, Colino J, Zelazowski P, Mond JJ, Gause WC, Wu ZQ. Distinct types of T-cell help for the induction of a humoral immune response to Streptococcus pneumoniae Trends in Immunology. 22: 308-311. PMID 11377289 DOI: 10.1016/S1471-4906(01)01926-3  0.476
2001 Jankovic D, Liu Z, Gause WC. Th1- or Th2-cell commitment during infectious disease: an oversimplification?: Response from Jankovic, Liu and Gause Trends in Immunology. 22: 482. DOI: 10.1016/S1471-4906(01)01998-6  0.587
2001 Madden KB, Mulloy DP, Urban JF, Gause WC, Fleming SD, Katona IM, Shea-Donohue T. Nematode infection induces stereotypic Th2 cytokine and Stat6-dependent changes in epithelial cell function Gastroenterology. 120. DOI: 10.1016/S0016-5085(08)80937-7  0.452
2001 Mulloy DP, Zhao A, Gause WC, Fleming S, Shea-Donohue T. Stat6 dependent inhibition of the epithelial cell responses to trichuris muris in murine colon Gastroenterology. 120. DOI: 10.1016/S0016-5085(08)80936-5  0.408
2000 Wu ZQ, Khan AQ, Shen Y, Schartman J, Peach R, Lees A, Mond JJ, Gause WC, Snapper CM. B7 requirements for primary and secondary protein- and polysaccharide-specific Ig isotype responses to Streptococcus pneumoniae Journal of Immunology. 165: 6840-6848. PMID 11120807 DOI: 10.4049/Jimmunol.165.12.6840  0.444
2000 Urban J, Fang H, Liu Q, Ekkens MJ, Chen SJ, Nguyen D, Mitro V, Donaldson DD, Byrd C, Peach R, Morris SC, Finkelman FD, Schopf L, Gause WC. IL-13-mediated worm expulsion is B7 independent and IFN-gamma sensitive. Journal of Immunology (Baltimore, Md. : 1950). 164: 4250-6. PMID 10754322 DOI: 10.4049/Jimmunol.164.8.4250  0.721
2000 Morris SC, Gause WC, Finkelman FD. IL-4 suppression of in vivo T cell activation and antibody production Journal of Immunology. 164: 1734-1740. PMID 10657618 DOI: 10.4049/Jimmunol.164.4.1734  0.562
1999 Gause WC, Ekkens M, Nguyen D, Mitro V, Liu Q, Finkelman FD, Greenwald RJ, Urban JF. The development of CD4+ T effector cells during the type 2 immune response Immunologic Research. 20: 55-65. PMID 10467983 DOI: 10.1007/Bf02786507  0.72
1999 Wu ZQ, Vos Q, Shen Y, Lees A, Wilson SR, Briles DE, Gause WC, Mond JJ, Snapper CM. In vivo polysaccharide-specific IgG isotype responses to intact Streptococcus pneumoniae are T cell dependent and require CD40- and B7- ligand interactions Journal of Immunology. 163: 659-667. PMID 10395655  0.368
1999 Greenwald RJ, Urban JF, Ekkens MJ, Chen SJ, Nguyen D, Fang H, Finkelman FD, Sharpe AH, Gause WC. B7-2 is required for the progression but not the initiation of the type 2 immune response to a gastrointestinal nematode parasite Journal of Immunology. 162: 4133-4139. PMID 10201938  0.506
1999 Luzina IG, Knitzer RH, Atamas SP, Gause WC, Papadimitriou JC, Sztein MB, Storrer CE, Handwerger BS. Vasculitis in the Palmerston North mouse model of lupus: Phenotype and cytokine production profile of infiltrating cells Arthritis and Rheumatism. 42: 561-568. PMID 10088780 DOI: 10.1002/1529-0131(199904)42:3<561::Aid-Anr22>3.0.Co;2-X  0.529
1999 Zhang Q, Zhou XD, Denny T, Ottenweller JE, Lange G, LaManca JJ, Lavietes MH, Pollet C, Gause WC, Natelson BH. Changes in immune parameters seen in Gulf War veterans but not in civilians with chronic fatigue syndrome. Clinical and Diagnostic Laboratory Immunology. 6: 6-13. PMID 9874656 DOI: 10.1128/Cdli.6.1.6-13.1999  0.543
1998 Mansfield LS, Urban JF, Holley-Shanks RR, Murtaugh MP, Zarlenga DS, Foss D, Canals A, Gause W, Lunney JK. Construction of internal cDNA competitors for measuring IL-10 and IL-12 cytokine gene expression in swine Veterinary Immunology and Immunopathology. 65: 63-74. PMID 9802577 DOI: 10.1016/S0165-2427(98)00106-8  0.492
1998 Keane-Myers AM, Gause WC, Finkelman FD, Xhou XD, Wills-Karp M. Development of murine allergic asthma is dependent upon B7-2 costimulation Journal of Immunology. 160: 1036-1043. PMID 9551945  0.46
1998 Kellman MF, Urban JF, Chen S, Greenwald RJ, Nguyen D, Gause WC. The systemic but not mucosal Th2 response to H. polygyrus is impaired in CD28KO mice Faseb Journal. 12.  0.439
1998 Greenwald RJ, Chen SJ, Nguyen D, Urban JF, Gause WC. CTLA-4 may deliver a positive T cell costimulatory signal at the initiation of a TH2 immune response in vivo Faseb Journal. 12.  0.435
1997 Gause WC, Mitro V, Via C, Linsley P, Urban JF, Greenwald RJ. Do effector and memory T helper cells also need B7 ligand costimulatory signals? Journal of Immunology (Baltimore, Md. : 1950). 159: 1055-1058. PMID 9233595  0.358
1997 Grieder FB, Davis BK, Zhou XD, Chen SJ, Finkelman FD, Gause WC. Kinetics of cytokine expression and regulation of host protection following infection with molecularly cloned Venezuelan equine encephalitis virus. Virology. 233: 302-12. PMID 9217054 DOI: 10.1006/Viro.1997.8617  0.526
1997 Finkelman FD, Shea-Donohue T, Goldhill J, Sullivan CA, Morris SC, Madden KB, Gause WC, Urban JF. Cytokine regulation of host defense against parasitic gastrointestinal nematodes: Lessons from studies with rodent models Annual Review of Immunology. 15: 505-533. PMID 9143698 DOI: 10.1146/Annurev.Immunol.15.1.505  0.509
1997 Greenwald RJ, Lu P, Halvorson MJ, Zhou XD, Chen SJ, Madden KB, Perrin PJ, Morris SC, Finkelman FD, Peach R, Linsley PS, Urban JF, Gause WC. Effects of Blocking B7-1 and B7-2 Interactions during a Type 2 in Vivo Immune Response Journal of Immunology. 158: 4088-4096. PMID 9126967  0.39
1997 Gause WC, Chen SJ, Greenwald RJ, Halvorson MJ, Lu P, Di Zhou X, Morris SC, Lee KP, June CH, Finkelman FD, Urban JF, Abe R. CD28 Dependence of T Cell Differentiation to IL-4 Production Varies with the Particular Type 2 Immune Response Journal of Immunology. 158: 4082-4087. PMID 9126966  0.546
1997 Gause WC, Halvorson MJ, Lu P, Greenwald R, Linsley P, Urban JF, Finkelman FD. The function of costimulatory molecules and the development of IL-4-producing T cells Immunology Today. 18: 115-120. PMID 9078683 DOI: 10.1016/S0167-5699(97)01005-0  0.567
1997 Keane-Myers A, Gause WC, Linsley PS, Chen SJ, Wills-Karp M. B7-CD28/CTLA-4 Costimulatory Pathways Are Required for the Development of T Helper Cell 2-Mediated Allergic Airway Responses to Inhaled Antigens Journal of Immunology. 158: 2042-2049. PMID 9036947  0.441
1996 Urban JF, Fayer R, Sullivan C, Goldhill J, Shea-Donohue T, Madden K, Morris SC, Katona I, Gause W, Ruff M, Mansfield LS, Finkelman FD. Local TH1 and TH2 responses to parasitic infection in the intestine: Regulation by IFN-gamma and IL-4 Veterinary Immunology and Immunopathology. 54: 337-344. PMID 8988879 DOI: 10.1016/S0165-2427(96)05708-X  0.589
1996 Scott P, Eaton A, Gause WC, di Zhou X, Hondowicz B. Early IL-4 production does not predict susceptibility to Leishmania major. Experimental Parasitology. 84: 178-87. PMID 8932767 DOI: 10.1006/Expr.1996.0103  0.542
1996 Via CS, Rus V, Nguyen P, Linsley P, Gause WC. Differential Effect of CTLA4Ig on Murine Graft-Versus-Host Disease (GVHD) Development: CTLA4Ig Prevents Both Acute and Chronic GVHD Development but Reverses only Chronic GVHD Journal of Immunology. 157: 4258-4267. PMID 8892665  0.392
1996 Lu P, Urban JF, Di Zhou X, Chen SJ, Madden K, Moorman M, Nguyen H, Morris SC, Finkelman FD, Gause WC. CD40-mediated stimulation contributes to lymphocyte proliferation, antibody production, eosinophilia, and mastocytosis during an in vivo type 2 response, but is not required for T cell IL-4 production Journal of Immunology. 156: 3327-3333. PMID 8617957  0.498
1996 Urban JF, Fayer R, Chen SJ, Gause WC, Gately MK, Finkelman FD. IL-12 protects immunocompetent and immunodeficient neonatal mice against infection with Cryptosporidium parvum Journal of Immunology. 156: 263-268. PMID 8598471  0.454
1996 Finkelman FD, Lees A, Birnbaum R, Gause WC, Morris SC. Dendritic Cells Can Present Antigen in Vivo in a Tolerogenic or Immunogenic Fashion Journal of Immunology. 157: 1406-1414.  0.306
1996 Greenwald RJ, Urban JF, Lu P, Nguyen H, Finkelman F, Gause WC. Rapid upregulation and differential expression of B7 occurs during the course of a primary type 2 in vivo immune response Faseb Journal. 10.  0.362
1995 Gause WC, Urban JF, Linsley P, Lu P. Role of B7 signaling in the differentiation of naive CD4+ T cells to effector interleukin-4-producing T helper cells Immunologic Research. 14: 176-188. PMID 8778208 DOI: 10.1007/Bf02918215  0.59
1995 Lu P, Di Zhou X, Chen SJ, Moorman M, Schoneveld A, Morris S, Finkelman FD, Linsley P, Claassen E, Gause WC. Requirement of CTLA-4 counter receptors for IL-4 but not IL-10 elevations during a primary systemic in vivo immune response Journal of Immunology. 154: 1078-1087. PMID 7822784  0.517
1995 Rus V, Svetic A, Nguyen P, Gause WC, Via CS. Kinetics of Th1 and Th2 cytokine production during the early course of acute and chronic murine graft-versus-host disease: Regulatory role of donor CD8+ T cells Journal of Immunology. 155: 2396-2406. PMID 7650373  0.418
1994 Peterson VM, Adamovicz JJ, Elliott TB, Moore MM, Madonna GS, Jackson WE, Ledney GD, Gause WC. Gene expression of hematoregulatory cytokines is elevated endogenously after sublethal gamma irradiation and is differentially enhanced by therapeutic administration of biologic response modifiers Journal of Immunology. 153: 2321-2330. PMID 8051428  0.329
1994 Lu P, Zhou XD, Chen SJ, Moorman M, Morris SC, Finkelman FD, Linsley P, Urban JF, Gause WC. CTLA-4 ligands are required to induce an in vivo interleukin 4 response to a gastrointestinal nematode parasite Journal of Experimental Medicine. 180: 693-698. PMID 8046343 DOI: 10.1084/Jem.180.2.693  0.626
1994 Finkelman FD, Madden KB, Cheever AW, Katona IM, Morris SC, Gately MK, Hubbard BR, Gause WC, Urban JF. Effects of interleukin 12 on immune responses and host protection in mice infected with intestinal nematode parasites Journal of Experimental Medicine. 179: 1563-1572. PMID 7909327 DOI: 10.1084/Jem.179.5.1563  0.601
1994 Morris SC, Madden KB, Adamovicz JJ, Gause WC, Hubbard BR, Gately MK, Finkelman FD. Effects of IL-12 on in vivo cytokine gene expression and Ig isotype selection Journal of Immunology. 152: 1047-1056. PMID 7905496  0.428
1994 Wu J, Zhou T, Zhang J, He J, Gause WC, Mountz JD. Correction of accelerated autoimmune disease by early replacement of the mutated lpr gene with the normal Fas apoptosis gene in the T cells of transgenic MRL-lpr/lpr mice Proceedings of the National Academy of Sciences of the United States of America. 91: 2344-2348. PMID 7510888 DOI: 10.1073/Pnas.91.6.2344  0.374
1993 Svetić A, Madden KB, Zhou XD, Lu P, Katona IM, Finkelman FD, Urban JF, Gause WC. A primary intestinal helminthic infection rapidly induces a gut-associated elevation of Th2-associated cytokines and IL-3 1 Journal of Immunology. 150: 3434-3441. PMID 8468481  0.498
1993 Thyphronitis G, Katona IM, Gause WC, Finkelman FD. Germline and productive Cε gene expression during in vivo IgE responses Journal of Immunology. 151: 4128-4136. PMID 8409390  0.328
1993 Wynn TA, Eltoum I, Cheever AW, Lewis FA, Gause WC, Sher A. Analysis of cytokine mRNA expression during primary granuloma formation induced by eggs of Schistosoma mansoni Journal of Immunology. 151: 1430-1440. PMID 8335939  0.444
1993 Svetić A, Jian YC, Lu P, Finkeiman FD, Gause WC. Brucella abortus induces a novel cytokine gene expression pattern characterized by elevated IL-10 and IFN-γ in CD4+ T cells International Immunology. 5: 877-883. PMID 8104472 DOI: 10.1093/Intimm/5.8.877  0.59
1992 Urban JF, Madden KB, Svetić A, Cheever A, Trotta PP, Gause WC, Katona IM, Finkelman FD. The importance of Th2 cytokines in protective immunity to nematodes Immunological Reviews. 205-220. PMID 1354652 DOI: 10.1111/J.1600-065X.1992.Tb01415.X  0.496
1991 Finkelman FD, Svetic A, Gresser I, Snapper C, Holmes J, Trotta PP, Katona IM, Gause WC. Regulation by interferon α of immunoglobulin isotype selection and lymphokine production in mice Journal of Experimental Medicine. 174: 1179-1188. PMID 1940796 DOI: 10.1084/Jem.174.5.1179  0.458
1991 Takashi T, Gause WC, Wilkinson M, MacLeod CL, Steinberg AD. Interleukin 1-induced maturation of progenitor thymocytes European Journal of Immunology. 21: 1385-1390. PMID 1828425 DOI: 10.1002/Eji.1830210609  0.442
1991 Mountz JD, Gause WC, Jonsson R. Murine models for systemic lupus erythematosus and Sjogren's syndrome Current Opinion in Rheumatology. 3: 738-756. PMID 1751309 DOI: 10.1097/00002281-199110000-00004  0.515
1991 Svetic A, Finkelman FD, Jian YC, Dieffenbach CW, Scott DE, McCarthy KF, Steinberg AD, Gause WC. Cytokine gene expression after in vivo primary immunization with goat antibody to mouse IgD antibody Journal of Immunology. 147: 2391-2397. PMID 1717559  0.516
1990 Scott DE, Gause WC, Finkelman FD, Steinberg AD. Anti-CD3 antibody induces rapid expression of cytokine genes in vivo Journal of Immunology. 145: 2183-2188. PMID 2144547  0.451
1989 Takashi T, Steinberg AD, June CH, Gause WC. Responsiveness of fetal and adult CD4-, CD8- thymocytes to T cell activation Journal of Immunology. 142: 2641-2646. PMID 2564859  0.378
1988 Gause WC, Takashi T, Mountz JD, Finkelman FD, Steinberg AD. Activation of CD 4-, CD 8- thymocytes with IL 4 vs IL 1 + IL 2 Journal of Immunology. 141: 2240-2245. PMID 3262653  0.408
1987 Steinberg AD, Klinman DM, Kastner DL, Seldin MF, Gause WC, Scribner CL, Britten JL, Siegel JN, Mountz JD. Genetic and molecular genetic studies of murine and human lupus Journal of Rheumatology. 14: 166-176. PMID 3497269  0.303
1987 Gause WC, Mountz JD, Steinberg AD. Subpopulations of CD4-,CD8- thymocytes European Journal of Immunology. 17: 1387-1390. PMID 2958298 DOI: 10.1002/Eji.1830170927  0.357
1985 Gause WC, Marsh JA. Differential effects of thyroxine on immune development and autoimmune thyroiditis in the obese strain chicken Developmental and Comparative Immunology. 9: 465-475. PMID 4043483 DOI: 10.1016/0145-305X(85)90009-6  0.314
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