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Ashley C. Brown, Ph.D. - Publications

Affiliations: 
2011 Georgia Institute of Technology, Atlanta, GA 
Area:
Biomedical Engineering, Cell Biology, Biochemistry
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48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Chee E, Mihalko E, Nellenbach K, Sollinger J, Huang K, Hon M, Pandit S, Cheng K, Brown A. Wound-triggered shape change microgels for the development of enhanced biomimetic function platelet-like particles. Journal of Biomedical Materials Research. Part A. PMID 37846887 DOI: 10.1002/jbm.a.37625  0.312
2021 Nandi S, Mihalko E, Nellenbach K, Castaneda M, Schneible J, Harp M, Deal H, Daniele M, Menegatti S, Barker TH, Brown AC. Synthetic platelet microgels containing fibrin knob B mimetic motifs enhance clotting responses. Advanced Therapeutics. 4. PMID 34095458 DOI: 10.1002/adtp.202100010  0.609
2020 Nandi S, Mohanty K, Nellenbach K, Erb M, Muller M, Brown AC. Ultrasound enhanced synthetic platelet therapy for augmented wound repair. Acs Biomaterials Science & Engineering. 6: 3026-3036. PMID 33313395 DOI: 10.1021/acsbiomaterials.9b01976  0.334
2020 Sproul EP, Nandi S, Chee E, Sivadanam S, Igo BJ, Schreck L, Brown AC. Development of biomimetic antimicrobial platelet-like particles comprised of microgel nanogold composites. Regenerative Engineering and Translational Medicine. 6: 299-309. PMID 33225044 DOI: 10.1007/s40883-019-00121-6  0.305
2020 Nellenbach K, Nandi S, Peeler C, Kyu A, Brown AC. Neonatal Fibrin Scaffolds Promote Enhanced Cell Adhesion, Migration, and Wound Healing Compared to Adult Fibrin Scaffolds. Cellular and Molecular Bioengineering. 13: 393-404. PMID 33184573 DOI: 10.1007/S12195-020-00620-5  0.37
2020 Deal HE, Brown AC, Daniele MA. Microphysiological systems for the modeling of wound healing and evaluation of pro-healing therapies. Journal of Materials Chemistry. B. PMID 32756718 DOI: 10.1039/D0Tb00544D  0.342
2020 Nandi S, Sommerville L, Nellenbach K, Mihalko E, Erb M, Freytes DO, Hoffman M, Monroe D, Brown AC. Platelet-like particles improve fibrin network properties in a hemophilic model of provisional matrix structural defects. Journal of Colloid and Interface Science. 577: 406-418. PMID 32502667 DOI: 10.1016/J.Jcis.2020.05.088  0.413
2020 Chee E, Nandi S, Nellenbach K, Mihalko E, Snider DB, Morrill L, Bond A, Sproul E, Sollinger J, Cruse G, Hoffman M, Brown AC. Nanosilver composite pNIPAm microgels for the development of antimicrobial platelet-like particles. Journal of Biomedical Materials Research. Part B, Applied Biomaterials. PMID 32100966 DOI: 10.1002/Jbm.B.34592  0.376
2020 Nandi S, Mohanty K, Nellenbach K, Erb M, Muller M, Brown AC. Ultrasound Enhanced Synthetic Platelet Therapy for Augmented Wound Repair Acs Biomaterials Science & Engineering. 6: 3026-3036. DOI: 10.1021/Acsbiomaterials.9B01976  0.371
2019 Mihalko E, Brown AC. Clot Structure and Implications for Bleeding and Thrombosis. Seminars in Thrombosis and Hemostasis. PMID 31614389 DOI: 10.1055/S-0039-1696944  0.326
2019 Huebner P, Warren PB, Chester D, Spang JT, Brown AC, Fisher MB, Shirwaiker RA. Mechanical properties of tissue formed in vivo are affected by 3D-bioplotted scaffold microarchitecture and correlate with ECM collagen fiber alignment. Connective Tissue Research. 1-15. PMID 31345062 DOI: 10.1080/03008207.2019.1624733  0.363
2019 Nandi S, Sproul EP, Nellenbach K, Erb M, Gaffney L, Freytes DO, Brown AC. Platelet-like particles dynamically stiffen fibrin matrices and improve wound healing outcomes. Biomaterials Science. PMID 30608063 DOI: 10.1039/C8Bm01201F  0.432
2019 Muhamed I, Sproul E, Ligler FS, Brown AC. Fibrin nanoparticles coupled with keratinocyte growth factor enhance dermal wound healing rate. Acs Applied Materials & Interfaces. PMID 30604611 DOI: 10.1021/Acsami.8B21056  0.366
2018 Sproul EP, Nandi S, Roosa C, Schreck L, Brown AC. Biomimetic microgels with controllable deformability improve healing outcomes. Advanced Biosystems. 2. PMID 33564714 DOI: 10.1002/adbi.201800042  0.302
2018 Chester D, Kathard R, Nortey J, Nellenbach K, Brown AC. Viscoelastic properties of microgel thin films control fibroblast modes of migration and pro-fibrotic responses. Biomaterials. 185: 371-382. PMID 30292092 DOI: 10.1016/J.Biomaterials.2018.09.012  0.352
2018 Nellenbach K, Guzzetta NA, Brown AC. Analysis of the structural and mechanical effects of procoagulant agents on neonatal fibrin networks following cardiopulmonary bypass. Journal of Thrombosis and Haemostasis : Jth. PMID 30182421 DOI: 10.1111/Jth.14280  0.332
2018 Hardy ET, Wang YJ, Iyer S, Mannino RG, Sakurai Y, Barker TH, Chi T, Youn Y, Wang H, Brown AC, Lam WA. Interdigitated microelectronic bandage augments hemostasis and clot formation at low applied voltage in vitro and in vivo. Lab On a Chip. PMID 30109316 DOI: 10.1039/C8Lc00573G  0.572
2018 Mihalko E, Huang K, Sproul E, Cheng K, Brown AC. Targeted Treatment of Ischemic and Fibrotic Complications of Myocardial Infarction Using a Dual-Delivery Microgel Therapeutic. Acs Nano. PMID 30016078 DOI: 10.1021/Acsnano.8B01977  0.305
2018 Tang J, Su T, Huang K, Dinh PU, Wang Z, Vandergriff A, Hensley MT, Cores J, Allen T, Li T, Sproul E, Mihalko E, Lobo LJ, Ruterbories L, Lynch A, ... Brown A, et al. Targeted repair of heart injury by stem cells fused with platelet nanovesicles. Nature Biomedical Engineering. 2: 17-26. PMID 29862136 DOI: 10.1038/S41551-017-0182-X  0.39
2018 Sproul EP, Hannan RT, Brown AC. Controlling Fibrin Network Morphology, Polymerization, and Degradation Dynamics in Fibrin Gels for Promoting Tissue Repair. Methods in Molecular Biology (Clifton, N.J.). 1758: 85-99. PMID 29679324 DOI: 10.1007/978-1-4939-7741-3_7  0.389
2018 Welsch N, Brown AC, Barker TH, Lyon LA. Enhancing clot properties through fibrin-specific self-cross-linked PEG side-chain microgels. Colloids and Surfaces. B, Biointerfaces. 166: 89-97. PMID 29549720 DOI: 10.1016/J.Colsurfb.2018.03.003  0.629
2017 Nandi S, Brown AC. Characterizing Cell Migration Within Three-dimensional In Vitro Wound Environments. Journal of Visualized Experiments : Jove. PMID 28872146 DOI: 10.3791/56099  0.354
2017 Cao L, Nicosia J, Larouche J, Zhang Y, Bachman H, Brown AC, Holmgren L, Barker TH. Detection of an Integrin-Binding Mechanoswitch within Fibronectin during Tissue Formation and Fibrosis. Acs Nano. PMID 28699736 DOI: 10.1021/Acsnano.7B02755  0.622
2017 Joshi AA, Seema N, Brown A, Muller MM. Study of effects of ultrasound stimulation on platelet-like-particle mediated fibrin-network deformation The Journal of the Acoustical Society of America. 142: 2697-2697. DOI: 10.1121/1.5014837  0.39
2017 Mihalko EP, Brown AC. Material Strategies for Modulating Epithelial to Mesenchymal Transitions Acs Biomaterials Science & Engineering. 4: 1149-1161. DOI: 10.1021/Acsbiomaterials.6B00751  0.382
2016 Myers DR, Qiu Y, Fay ME, Tennenbaum M, Chester D, Cuadrado J, Sakurai Y, Baek J, Tran R, Ciciliano JC, Ahn B, Mannino RG, Bunting ST, Bennett C, Briones M, ... ... Brown AC, et al. Single-platelet nanomechanics measured by high-throughput cytometry. Nature Materials. PMID 27723740 DOI: 10.1038/Nmat4772  0.413
2016 Chester D, Brown AC. The role of biophysical properties of provisional matrix proteins in wound repair. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 27534610 DOI: 10.1016/J.Matbio.2016.08.004  0.341
2016 Nandi S, Brown AC. Platelet-mimetic strategies for modulating the wound environment and inflammatory responses. Experimental Biology and Medicine (Maywood, N.J.). PMID 27190260 DOI: 10.1177/1535370216647126  0.412
2016 Brown AC, Hannan RH, Timmins LH, Fernandez JD, Barker TH, Guzzetta NA. Fibrin Network Changes in Neonates after Cardiopulmonary Bypass. Anesthesiology. PMID 26914227 DOI: 10.1097/Aln.0000000000001058  0.541
2015 Karumbaiah L, Enam SF, Brown AC, Saxena T, Betancur MI, Barker TH, Bellamkonda RV. Chondroitin Sulfate Glycosaminoglycan Hydrogels Create Endogenous Niches for Neural Stem Cells. Bioconjugate Chemistry. PMID 26440046 DOI: 10.1021/Acs.Bioconjchem.5B00397  0.569
2015 Brown AC, Dysart MM, Clarke KC, Stabenfeldt SE, Barker TH. Integrin α3β1 binding to fibronectin is dependent on the 9th type III repeat. The Journal of Biological Chemistry. PMID 26318455 DOI: 10.1074/Jbc.M115.656702  0.564
2015 Brown AC, Baker SR, Douglas AM, Keating M, Alvarez-Elizondo MB, Botvinick EL, Guthold M, Barker TH. Molecular interference of fibrin's divalent polymerization mechanism enables modulation of multiscale material properties. Biomaterials. 49: 27-36. PMID 25725552 DOI: 10.1016/J.Biomaterials.2015.01.010  0.555
2015 Bachman H, Brown AC, Clarke KC, Dhada KS, Douglas A, Hansen CE, Herman E, Hyatt JS, Kodlekere P, Meng Z, Saxena S, Spears MW, Welsch N, Lyon LA. Ultrasoft, highly deformable microgels. Soft Matter. 11: 2018-28. PMID 25648590 DOI: 10.1039/C5Sm00047E  0.303
2014 Barker TH, Dysart MM, Brown AC, Douglas AM, Fiore VF, Russell AG. Synergistic effects of particulate matter and substrate stiffness on epithelial-to-mesenchymal transition. Research Report (Health Effects Institute). 3-41. PMID 25669020  0.555
2014 Qiu Y, Brown AC, Myers DR, Sakurai Y, Mannino RG, Tran R, Ahn B, Hardy ET, Kee MF, Kumar S, Bao G, Barker TH, Lam WA. Platelet mechanosensing of substrate stiffness during clot formation mediates adhesion, spreading, and activation. Proceedings of the National Academy of Sciences of the United States of America. 111: 14430-5. PMID 25246564 DOI: 10.1073/Pnas.1322917111  0.629
2014 Brown AC, Stabenfeldt SE, Ahn B, Hannan RT, Dhada KS, Herman ES, Stefanelli V, Guzzetta N, Alexeev A, Lam WA, Lyon LA, Barker TH. Ultrasoft microgels displaying emergent platelet-like behaviours. Nature Materials. 13: 1108-14. PMID 25194701 DOI: 10.1038/Nmat4066  0.629
2014 Bryksin AV, Brown AC, Baksh MM, Finn MG, Barker TH. Learning from nature - Novel synthetic biology approaches for biomaterial design Acta Biomaterialia. 10: 1761-1769. PMID 24463066 DOI: 10.1016/J.Actbio.2014.01.019  0.568
2014 Brown AC, Barker TH. Fibrin-based biomaterials: modulation of macroscopic properties through rational design at the molecular level. Acta Biomaterialia. 10: 1502-14. PMID 24056097 DOI: 10.1016/J.Actbio.2013.09.008  0.611
2014 Qiu Y, Brown AC, Myers DR, Sakurai Y, Mannino R, Tran R, Ahn B, Hardy E, Kee MF, Kumar S, Bao G, Barker TH, Lam WA. Platelet Adhesion, Spreading and Activation Are Mediated By Mechanosensing of Matrix Stiffness Blood. 124: 1438-1438. DOI: 10.1182/Blood.V124.21.1438.1438  0.636
2014 Kim J, Park Y, Brown AC, Lyon LA. Direct observation of ligand-induced receptor dimerization with a bioresponsive hydrogel Rsc Advances. 4: 65173-65175. DOI: 10.1039/C4Ra13251C  0.324
2013 Brown AC, Fiore VF, Sulchek TA, Barker TH. Physical and chemical microenvironmental cues orthogonally control the degree and duration of fibrosis-associated epithelial-to-mesenchymal transitions. The Journal of Pathology. 229: 25-35. PMID 23018598 DOI: 10.1002/Path.4114  0.619
2013 Clarke KC, Douglas AM, Brown AC, Barker TH, Lyon LA. Colloid-matrix assemblies in regenerative medicine Current Opinion in Colloid and Interface Science. 18: 393-405. DOI: 10.1016/J.Cocis.2013.07.004  0.597
2012 Markowski MC, Brown AC, Barker TH. Directing epithelial to mesenchymal transition through engineered microenvironments displaying orthogonal adhesive and mechanical cues. Journal of Biomedical Materials Research. Part A. 100: 2119-27. PMID 22615133 DOI: 10.1002/Jbm.A.34068  0.637
2012 Qiu Y, Brown AC, Jung WJ, Sakurai Y, Mannino R, Myers DR, Tran R, Bao G, Barker TH, Lam W. Platelet Mechanosensing: Adhesion and Spreading On Immobilized Fibrinogen Depends On Substrate Stiffness Blood. 120: 384-384. DOI: 10.1182/Blood.V120.21.384.384  0.634
2012 Myers DR, Brown AC, Qiu Y, Sakurai Y, Tran R, Ahn B, Mannino R, Sulchek T, Lyon A, Barker TH, Lam W. High-Throughput Nanomechanical Platelet Contraction Measurements Using Patterned Hydrogels. Blood. 120: 2172-2172. DOI: 10.1182/Blood.V120.21.2172.2172  0.62
2012 Schnaar R, Paulson JC, Macauley MS, Nycholat C, Pfrengle F, Rademacher C, Mahan A, Dionne K, Suscovich T, Alter G, Katoh T, Kiwamoto T, Brummet M, Bochner B, Tiemeyer M, ... ... Brown A, et al. Program and abstracts for the 2012 Joint Meeting of the Society for Glycobiology & American Society for Matrix Biology Glycobiology. 22: 1518-1650. DOI: 10.1093/Glycob/Cws127  0.582
2011 Brown AC, Rowe JA, Barker TH. Guiding epithelial cell phenotypes with engineered integrin-specific recombinant fibronectin fragments. Tissue Engineering. Part A. 17: 139-50. PMID 20695776 DOI: 10.1089/Ten.Tea.2010.0199  0.621
2010 Park ES, Brown AC, DiFeo MA, Barker TH, Lu H. Continuously perfused, non-cross-contaminating microfluidic chamber array for studying cellular responses to orthogonal combinations of matrix and soluble signals. Lab On a Chip. 10: 571-80. PMID 20162232 DOI: 10.1039/B919294H  0.594
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