Year |
Citation |
Score |
2018 |
Limpose KL, Trego KS, Li Z, Leung SW, Sarker AH, Shah JA, Ramalingam SS, Werner EM, Dynan WS, Cooper PK, Corbett AH, Doetsch PW. Overexpression of the base excision repair NTHL1 glycosylase causes genomic instability and early cellular hallmarks of cancer. Nucleic Acids Research. PMID 29522130 DOI: 10.1093/Nar/Gky162 |
0.309 |
|
2017 |
Li S, Shu FJ, Li Z, Jaafar L, Zhao S, Dynan WS. Cell-type specific role of the RNA-binding protein, NONO, in the DNA double-strand break response in the mouse testes. Dna Repair. PMID 28209515 DOI: 10.1016/j.dnarep.2017.02.002 |
0.329 |
|
2016 |
Jaafar L, Li Z, Li S, Dynan WS. SFPQ•NONO and XLF function separately and together to promote DNA double-strand break repair via canonical nonhomologous end joining. Nucleic Acids Research. PMID 27924002 DOI: 10.1093/nar/gkw1209 |
0.335 |
|
2015 |
Udayakumar D, Dynan WS. Characterization of DNA binding and pairing activities associated with the native SFPQ·NONO DNA repair protein complex. Biochemical and Biophysical Research Communications. 463: 473-8. PMID 25998385 DOI: 10.1016/J.Bbrc.2015.05.024 |
0.696 |
|
2014 |
Li S, Li Z, Shu FJ, Xiong H, Phillips AC, Dynan WS. Double-strand break repair deficiency in NONO knockout murine embryonic fibroblasts and compensation by spontaneous upregulation of the PSPC1 paralog. Nucleic Acids Research. 42: 9771-80. PMID 25100870 DOI: 10.1093/nar/gku650 |
0.301 |
|
2014 |
Dynan W, Fox K, Stoddard B. Editorial: NAR surveys the past, present and future of restriction endonucleases. Nucleic Acids Research. 42: 1-2. PMID 24376271 DOI: 10.1093/Nar/Gkt1324 |
0.324 |
|
2014 |
Li Z, Hudson FZ, Wang H, Wang Y, Murnane JP, Dynan WS. Mutagenic joining of enzymatically induced DNA double-strand breaks, accompanied by persistent unrepaired DNA damage and a secretory protein phenotype, in HZE-exposed human cells Journal of Radiation Research. 55: i85-i86. DOI: 10.1093/jrr/rrt169 |
0.319 |
|
2012 |
Xiong H, Lee RJ, Haura EB, Edwards JG, Dynan WS, Li S. Intranuclear delivery of a novel antibody-derived radiosensitizer targeting the DNA-dependent protein kinase catalytic subunit. International Journal of Radiation Oncology, Biology, Physics. 83: 1023-30. PMID 22138455 DOI: 10.1016/J.Ijrobp.2011.08.039 |
0.427 |
|
2011 |
Ha K, Takeda Y, Dynan WS. Sequences in PSF/SFPQ mediate radioresistance and recruitment of PSF/SFPQ-containing complexes to DNA damage sites in human cells. Dna Repair. 10: 252-9. PMID 21144806 DOI: 10.1016/J.Dnarep.2010.11.009 |
0.432 |
|
2011 |
Meiler SE, Dynan WS, Porteus M, Spector DL, Bao G, Chen Z, Pandey J, Goyal D, Kumaran RI, Wade M, Agyekum D. A Biological Delivery Platform for Zinc Finger Nucleases Using Transferrin-Mediated Endocytosis Blood. 118: 1071-1071. DOI: 10.1182/Blood.V118.21.1071.1071 |
0.376 |
|
2010 |
Norton JA, Weinberger PM, Waller JL, Merkley MA, Jackson LL, Dynan WS. Significance of HSPB1 expression in head and neck squamous cell carcinoma: a meta-analysis of published literatures. The Laryngoscope. 120: S172. PMID 21225770 DOI: 10.1002/Lary.21636 |
0.756 |
|
2010 |
Norton JA, Weinberger PM, Merkley MA, Khichi SS, Jackson LL, Dynan WS. Multi-spectral imaging analysis of HSPB1 expression in head and neck squamous cell carcinoma. The Laryngoscope. 120: S171. PMID 21225769 DOI: 10.1002/Lary.21635 |
0.749 |
|
2010 |
Weinberger PM, Merkley MA, Khichi SS, Lee JR, Psyrri A, Jackson LL, Dynan WS. Human papillomavirus-active head and neck cancer and ethnic health disparities. The Laryngoscope. 120: 1531-7. PMID 20564751 DOI: 10.1002/Lary.20984 |
0.741 |
|
2010 |
Cao Z, Kuhne WW, Steeb J, Merkley MA, Zhou Y, Janata J, Dynan WS. Use of a microscope stage-mounted Nickel-63 microirradiator for real-time observation of the DNA double-strand break response. Nucleic Acids Research. 38: e144. PMID 20484377 DOI: 10.1093/Nar/Gkq409 |
0.72 |
|
2010 |
Weinberger PM, Merkley M, Jackson L, Dynan WS. Abstract 3286: Overexpression of cornulin in histologically normal adjacent tissue predicts occult nodal metastases in head and neck cancer patients Cancer Research. 70: 3286-3286. DOI: 10.1158/1538-7445.Am10-3286 |
0.773 |
|
2009 |
Merkley MA, Weinberger PM, Jackson LL, Podolsky RH, Lee JR, Dynan WS. 2D-DIGE proteomic characterization of head and neck squamous cell carcinoma. Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery. 141: 626-32. PMID 19861202 DOI: 10.1016/J.Otohns.2009.08.011 |
0.782 |
|
2009 |
Arnouk H, Merkley MA, Podolsky RH, Stöppler H, Santos C, Alvarez M, Mariategui J, Ferris D, Lee JR, Dynan WS. Characterization of Molecular Markers Indicative of Cervical Cancer Progression. Proteomics. Clinical Applications. 3: 516-527. PMID 19834583 DOI: 10.1002/Prca.200800068 |
0.766 |
|
2009 |
Li S, Kuhne WW, Kulharya A, Hudson FZ, Ha K, Cao Z, Dynan WS. Involvement of p54(nrb), a PSF partner protein, in DNA double-strand break repair and radioresistance. Nucleic Acids Research. 37: 6746-53. PMID 19759212 DOI: 10.1093/Nar/Gkp741 |
0.419 |
|
2009 |
Lin Y, Buckhaults PJ, Lee JR, Xiong H, Farrell C, Podolsky RH, Schade RR, Dynan WS. Association of the actin-binding protein transgelin with lymph node metastasis in human colorectal cancer. Neoplasia (New York, N.Y.). 11: 864-73. PMID 19724680 DOI: 10.1593/Neo.09542 |
0.368 |
|
2009 |
Merkley MA, Hildebrandt E, Podolsky RH, Arnouk H, Ferris DG, Dynan WS, Stöppler H. Large-scale analysis of protein expression changes in human keratinocytes immortalized by human papilloma virus type 16 E6 and E7 oncogenes. Proteome Science. 7: 29. PMID 19698150 DOI: 10.1186/1477-5956-7-29 |
0.76 |
|
2009 |
Weinberger PM, Merkley M, Lee JR, Adam BL, Gourin CG, Podolsky RH, Haffty BG, Papadavid E, Sasaki C, Psyrri A, Dynan WS. Use of combination proteomic analysis to demonstrate molecular similarity of head and neck squamous cell carcinoma arising from different subsites. Archives of Otolaryngology--Head & Neck Surgery. 135: 694-703. PMID 19620592 DOI: 10.1001/Archoto.2009.78 |
0.777 |
|
2009 |
Xiong H, Li S, Yang Z, Burgess RR, Dynan WS. E. coli expression of a soluble, active single-chain antibody variable fragment containing a nuclear localization signal. Protein Expression and Purification. 66: 172-80. PMID 19281848 DOI: 10.1016/J.Pep.2009.03.002 |
0.592 |
|
2009 |
Lin Y, Dynan WS, Lee JR, Zhu ZH, Schade RR. The current state of proteomics in GI oncology. Digestive Diseases and Sciences. 54: 431-57. PMID 19104933 DOI: 10.1007/S10620-008-0656-5 |
0.325 |
|
2008 |
Dynan W, Takeda Y, Roth D, Bao G. Understanding and re-engineering nucleoprotein machines to cure human disease. Nanomedicine (London, England). 3: 93-105. PMID 18393669 DOI: 10.2217/17435889.3.1.93 |
0.375 |
|
2008 |
Lin Y, Lee J, Meeh P, Farrell C, Buckhaults P, Podolsky R, Schade R, Dynan W. Identification of Protein Biomarkers Associated with Lymph Node Metastasis in Colorectal Cancer American Journal of Gastroenterology. 103: S201-S202. DOI: 10.14309/00000434-200809001-00520 |
0.31 |
|
2008 |
Weinberger PM, Merkley MA, Jeffrey L, Gourin CG, Podolsky R, Sasaki CT, Amanda P, Dynan W. Molecular Similarity of HNSCC from Different Subsites Otolaryngology–Head and Neck Surgery. 139: P92-P92. DOI: 10.1016/J.Otohns.2008.05.499 |
0.779 |
|
2007 |
Bladen CL, Flowers MA, Miyake K, Podolsky RH, Barrett JT, Kozlowski DJ, Dynan WS. Quantification of ionizing radiation-induced cell death in situ in a vertebrate embryo. Radiation Research. 168: 149-57. PMID 17638406 DOI: 10.1667/Rr0803.1 |
0.303 |
|
2007 |
Bladen CL, Navarre S, Dynan WS, Kozlowski DJ. Expression of the Ku70 subunit (XRCC6) and protection from low dose ionizing radiation during zebrafish embryogenesis. Neuroscience Letters. 422: 97-102. PMID 17630212 DOI: 10.1016/J.Neulet.2007.05.045 |
0.408 |
|
2006 |
Dynan WS, Takeda Y, Li S. Modifying the function of DNA repair nanomachines for therapeutic benefit. Nanomedicine : Nanotechnology, Biology, and Medicine. 2: 74-81. PMID 17292118 DOI: 10.1016/J.Nano.2006.04.004 |
0.396 |
|
2006 |
Jovanovic M, Dynan WS. Terminal DNA structure and ATP influence binding parameters of the DNA-dependent protein kinase at an early step prior to DNA synapsis. Nucleic Acids Research. 34: 1112-20. PMID 16488883 DOI: 10.1093/Nar/Gkj504 |
0.641 |
|
2005 |
Greengauz-Roberts O, Stöppler H, Nomura S, Yamaguchi H, Goldenring JR, Podolsky RH, Lee JR, Dynan WS. Saturation labeling with cysteine-reactive cyanine fluorescent dyes provides increased sensitivity for protein expression profiling of laser-microdissected clinical specimens. Proteomics. 5: 1746-57. PMID 15761955 DOI: 10.1002/Pmic.200401068 |
0.403 |
|
2005 |
Bladen CL, Udayakumar D, Takeda Y, Dynan WS. Identification of the polypyrimidine tract binding protein-associated splicing factor.p54(nrb) complex as a candidate DNA double-strand break rejoining factor. The Journal of Biological Chemistry. 280: 5205-10. PMID 15590677 DOI: 10.1074/Jbc.M412758200 |
0.713 |
|
2005 |
Dynan W. Nanomachines for DNA repair Nanomedicine: Nanotechnology, Biology and Medicine. 1: 249-250. DOI: 10.1016/J.Nano.2005.09.026 |
0.363 |
|
2004 |
Lee KJ, Jovanovic M, Udayakumar D, Bladen CL, Dynan WS. Identification of DNA-PKcs phosphorylation sites in XRCC4 and effects of mutations at these sites on DNA end joining in a cell-free system. Dna Repair. 3: 267-76. PMID 15177042 DOI: 10.1016/J.Dnarep.2003.11.005 |
0.776 |
|
2003 |
Li S, Takeda Y, Wragg S, Barrett J, Phillips A, Dynan WS. Modification of the ionizing radiation response in living cells by an scFv against the DNA-dependent protein kinase. Nucleic Acids Research. 31: 5848-57. PMID 14530433 DOI: 10.1093/Nar/Gkg775 |
0.437 |
|
2003 |
Udayakumar D, Bladen CL, Hudson FZ, Dynan WS. Distinct pathways of nonhomologous end joining that are differentially regulated by DNA-dependent protein kinase-mediated phosphorylation. The Journal of Biological Chemistry. 278: 41631-5. PMID 12917393 DOI: 10.1074/Jbc.M306470200 |
0.708 |
|
2002 |
Mo X, Dynan WS. Subnuclear localization of Ku protein: functional association with RNA polymerase II elongation sites. Molecular and Cellular Biology. 22: 8088-99. PMID 12391174 DOI: 10.1128/Mcb.22.22.8088-8099.2002 |
0.445 |
|
2002 |
Lee KJ, Dong X, Wang J, Takeda Y, Dynan WS. Identification of human autoantibodies to the DNA ligase IV/XRCC4 complex and mapping of an autoimmune epitope to a potential regulatory region. Journal of Immunology (Baltimore, Md. : 1950). 169: 3413-21. PMID 12218164 DOI: 10.4049/Jimmunol.169.6.3413 |
0.615 |
|
2002 |
Huang J, Dynan WS. Reconstitution of the mammalian DNA double-strand break end-joining reaction reveals a requirement for an Mre11/Rad50/NBS1-containing fraction. Nucleic Acids Research. 30: 667-74. PMID 11809878 DOI: 10.1093/Nar/30.3.667 |
0.447 |
|
2001 |
Takeda Y, Dynan WS. Autoantibodies against DNA double-strand break repair proteins Frontiers in Bioscience : a Journal and Virtual Library. 6. PMID 11689355 |
0.342 |
|
2001 |
Jafri F, Hardin JA, Dynan WS. A method to detect particle-specific antibodies against Ku and the DNA-dependent protein kinase catalytic subunit in autoimmune sera Journal of Immunological Methods. 251: 53-61. PMID 11292481 DOI: 10.1016/S0022-1759(01)00294-0 |
0.43 |
|
2001 |
Woodard RL, Lee KJ, Huang J, Dynan WS. Distinct roles for Ku protein in transcriptional reinitiation and DNA repair. The Journal of Biological Chemistry. 276: 15423-33. PMID 11278739 DOI: 10.1074/Jbc.M010752200 |
0.611 |
|
2000 |
Lee KJ, Huang J, Takeda Y, Dynan WS. DNA ligase IV and XRCC4 form a stable mixed tetramer that functions synergistically with other repair factors in a cell-free end-joining system. The Journal of Biological Chemistry. 275: 34787-96. PMID 10945980 DOI: 10.1074/Jbc.M004011200 |
0.625 |
|
1999 |
Yoo S, Dynan WS. Geometry of a complex formed by double strand break repair proteins at a single DNA end: Recruitment of DNA-PKcs induces inward translocation of Ku protein Nucleic Acids Research. 27: 4679-4686. PMID 10572166 DOI: 10.1093/Nar/27.24.4679 |
0.461 |
|
1999 |
Kimzey AL, Dynan WS. Identification of a human T-cell leukemia virus type I tax peptide in contact with DNA Journal of Biological Chemistry. 274: 34226-34232. PMID 10567395 DOI: 10.1074/jbc.274.48.34226 |
0.301 |
|
1999 |
Yoo S, Kimzey A, Dynan WS. Photocross-linking of an oriented DNA repair complex: Ku bound at a single DNA end Journal of Biological Chemistry. 274: 20034-20039. PMID 10391954 DOI: 10.1074/jbc.274.28.20034 |
0.305 |
|
1999 |
Nueda A, Hudson F, Mivechi NF, Dynan WS. DNA-dependent protein kinase protects against heat-induced apoptosis Journal of Biological Chemistry. 274: 14988-14996. PMID 10329701 DOI: 10.1074/Jbc.274.21.14988 |
0.432 |
|
1999 |
Woodard RL, Anderson MG, Dynan WS. Nuclear extracts lacking DNA-dependent protein kinase are deficient in multiple round transcription. The Journal of Biological Chemistry. 274: 478-85. PMID 9867868 DOI: 10.1074/Jbc.274.1.478 |
0.434 |
|
1998 |
Kimzey AL, Dynan WS. Specific regions of contact between human T-cell leukemia virus type I Tax protein and DNA identified by photocross-linking Journal of Biological Chemistry. 273: 13768-13775. PMID 9593719 DOI: 10.1074/jbc.273.22.13768 |
0.323 |
|
1998 |
Dynan WS, Yoo S. Interaction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acids Nucleic Acids Research. 26: 1551-1559. PMID 9512523 DOI: 10.1093/Nar/26.7.1551 |
0.472 |
|
1998 |
Yoo S, Dynan WS. Characterization of the RNA binding properties of Ku protein Biochemistry. 37: 1336-1343. PMID 9477961 DOI: 10.1021/Bi972100W |
0.432 |
|
1997 |
Kim J, Nueda A, Meng YH, Dynan WS, Mivechi NF. Analysis of the phosphorylation of human heat shock transcription factor-1 by MAP kinase family members Journal of Cellular Biochemistry. 67: 43-54. PMID 9328838 DOI: 10.1002/(Sici)1097-4644(19971001)67:1<43::Aid-Jcb5>3.0.Co;2-W |
0.312 |
|
1997 |
Huang J, Nueda A, Yoo S, Dynan WS. Heat shock transcription factor 1 binds selectively in vitro to ku protein and the catalytic subunit of the DNA-dependent protein kinase Journal of Biological Chemistry. 272: 26009-26016. PMID 9325337 DOI: 10.1074/Jbc.272.41.26009 |
0.446 |
|
1997 |
McConnell KR, Dynan WS, Hardin JA. The DNA-Dependent Protein Kinase Catalytic Subunit (p460) is Cleaved during Fas-Mediated Apoptosis in Jurkat Cells Journal of Immunology. 158: 2083-2089. PMID 9036952 |
0.314 |
|
1996 |
McConnell K, Dynan WS. The DNA-dependent protein kinase: A matter of life and (cell) death Current Opinion in Cell Biology. 8: 325-330. PMID 8743882 DOI: 10.1016/S0955-0674(96)80005-6 |
0.421 |
|
1996 |
Suwa A, Hirakata M, Takeda Y, Okano Y, Mimori T, Inada S, Watanabe F, Teraoka H, Dynan WS, Hardin JA. Autoantibodies to DNA-dependent protein kinase probes for the catalytic subunit Journal of Clinical Investigation. 97: 1417-1421. PMID 8617873 |
0.348 |
|
1995 |
Peterson SR, Jesch SA, Chamberlin TN, Dvir A, Rabindran SK, Wu C, Dynan WS. Stimulation of the DNA-dependent protein kinase by RNA polymerase II transcriptional activator proteins. The Journal of Biological Chemistry. 270: 1449-54. PMID 7836414 DOI: 10.1074/Jbc.270.3.1449 |
0.341 |
|
1995 |
Peterson SR, Kurimasa A, Oshimura M, Dynan WS, Bradbury EM, Chen DJ. Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 92: 3171-4. PMID 7724535 |
0.346 |
|
1994 |
Anderson MG, Dynan WS. Quantitative studies of the effect of HTLV-I Tax protein on CREB protein--DNA binding. Nucleic Acids Research. 22: 3194-201. PMID 8065935 DOI: 10.1093/Nar/22.15.3194 |
0.431 |
|
1992 |
Peterson SR, Dvir A, Anderson CW, Dynan WS. DNA binding provides a signal for phosphorylation of the RNA polymerase II heptapeptide repeats Genes and Development. 6: 426-438. PMID 1547941 DOI: 10.1101/gad.6.3.426 |
0.345 |
|
1991 |
Arias JA, Peterson SR, Dynan WS. Promoter-dependent phosphorylation of RNA polymerase II by a template-bound kinase. Association with transcriptional initiation. The Journal of Biological Chemistry. 266: 8055-61. PMID 1708770 |
0.641 |
|
1990 |
Ayer DE, Dynan WS. A Downstream-Element-Binding Factor Facilitates Assembly of a Functional Preinitiation Complex at the Simian Virus 40 Major Late Promoter Molecular and Cellular Biology. 10: 3635-3645. PMID 2162478 DOI: 10.1128/Mcb.10.7.3635 |
0.637 |
|
1989 |
Letovsky J, Dynan WS. Measurement of the binding of transcription factor Sp1 to a single GC box recognition sequence Nucleic Acids Research. 17: 2639-2653. PMID 2717405 DOI: 10.1093/Nar/17.7.2639 |
0.33 |
|
1989 |
Arias JA, Dynan WS. Promoter-dependent transcription by RNA polymerase II using immobilized enzyme complexes. The Journal of Biological Chemistry. 264: 3223-9. PMID 2464595 |
0.629 |
|
1988 |
Ayer DE, Dynan WS. Simian virus 40 major late promoter: a novel tripartite structure that includes intragenic sequences Molecular and Cellular Biology. 8: 2021-2033. PMID 2838741 DOI: 10.1128/Mcb.8.5.2021 |
0.594 |
|
1988 |
Nyborg JK, Dynan WS, Chen IS, Wachsman W. Binding of host-cell factors to DNA sequences in the long terminal repeat of human T-cell leukemia virus type I: implications for viral gene expression. Proceedings of the National Academy of Sciences of the United States of America. 85: 1457-61. PMID 2830620 |
0.332 |
|
1981 |
Dynan WS, Burgess RR. In vitro transcription by wheat germ RNA polymerase II. Initiation of RNA synthesis on relaxed, closed circular template Journal of Biological Chemistry. 256: 5866-5873. PMID 6263893 |
0.541 |
|
1981 |
Dynan WS, Jendrisak JJ, Hager DA, Burgess RR. Purification and characterization of wheat germ DNA topoisomerase I (nicking-closing enzyme) Journal of Biological Chemistry. 256: 5860-5865. PMID 6263892 |
0.52 |
|
1979 |
Dynan WS, Burgess RR. In vitro transcription by wheat germ ribonucleic acid polymerase II: Effects of heparin and role of template integrity Biochemistry. 18: 4581-4588. PMID 387073 DOI: 10.1021/Bi00588A019 |
0.589 |
|
1977 |
Dynan WS, Jendrisak JJ, Burgess RR. Templates for eukaryotic RNA polymerase II: Artefacts can produce an apparent preference for denatured DNA over native DNA Analytical Biochemistry. 79: 181-189. PMID 869175 DOI: 10.1016/0003-2697(77)90392-X |
0.549 |
|
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