Year |
Citation |
Score |
2023 |
Leung CLK, Karunakaran S, Atser MG, Innala L, Hu X, Viau V, Johnson JD, Clee SM. Analysis of a genetic region affecting mouse body weight. Physiological Genomics. PMID 36717164 DOI: 10.1152/physiolgenomics.00137.2022 |
0.303 |
|
2019 |
Pereira S, O'Dwyer SM, Webber TD, Baker RK, So V, Ellis CE, Yoon JS, Mojibian M, Glavas MM, Karunakaran S, Clee SM, Covey SD, Kieffer TJ. Metabolic effects of leptin receptor knockdown or reconstitution in adipose tissues. Scientific Reports. 9: 3307. PMID 30824713 DOI: 10.1038/S41598-019-39498-3 |
0.371 |
|
2018 |
Karunakaran S, Clee SM. Genetics of metabolic syndrome: potential clues from wild-derived inbred mouse strains. Physiological Genomics. 50: 35-51. PMID 29127221 DOI: 10.1152/Physiolgenomics.00059.2017 |
0.319 |
|
2016 |
D'souza AM, Johnson JD, Clee SM, Kieffer TJ. Suppressing hyperinsulinemia prevents obesity but causes rapid onset of diabetes in leptin-deficient Lep(ob/ob) mice. Molecular Metabolism. 5: 1103-1112. PMID 27818936 DOI: 10.1016/J.Molmet.2016.09.007 |
0.372 |
|
2016 |
Denroche HC, Glavas MM, Tudurí E, Karunakaran S, Quong WL, Philippe M, Britton HM, Clee SM, Kieffer TJ. Disrupted leptin signaling in the lateral hypothalamus and ventral premammillary nucleus alters insulin and glucagon secretion and protects against diet-induced obesity. Endocrinology. en20151998. PMID 27183315 DOI: 10.1210/En.2015-1998 |
0.362 |
|
2016 |
Dionne DA, Skovsø S, Templeman NM, Clee SM, Johnson JD. Caloric restriction paradoxically increases adiposity in mice with genetically reduced insulin. Endocrinology. en20161102. PMID 27145011 DOI: 10.1210/En.2016-1102 |
0.354 |
|
2015 |
Lim GE, Albrecht T, Piske M, Sarai K, Lee JT, Ramshaw HS, Sinha S, Guthridge MA, Acker-Palmer A, Lopez AF, Clee SM, Nislow C, Johnson JD. 14-3-3ζ coordinates adipogenesis of visceral fat. Nature Communications. 6: 7671. PMID 26220403 DOI: 10.1038/Ncomms8671 |
0.34 |
|
2015 |
Templeman NM, Clee SM, Johnson JD. Suppression of hyperinsulinaemia in growing female mice provides long-term protection against obesity. Diabetologia. PMID 26155745 DOI: 10.1007/S00125-015-3676-7 |
0.404 |
|
2015 |
Denroche HC, Kwon MM, Quong WL, Neumann UH, Kulpa JE, Karunakaran S, Clee SM, Brownsey RW, Covey SD, Kieffer TJ. Leptin induces fasting hypoglycaemia in a mouse model of diabetes through the depletion of glycerol. Diabetologia. 58: 1100-8. PMID 25715699 DOI: 10.1007/S00125-015-3529-4 |
0.315 |
|
2013 |
Ho MM, Yoganathan P, Chu KY, Karunakaran S, Johnson JD, Clee SM. Diabetes genes identified by genome-wide association studies are regulated in mice by nutritional factors in metabolically relevant tissues and by glucose concentrations in islets. Bmc Genetics. 14: 10. PMID 23442068 DOI: 10.1186/1471-2156-14-10 |
0.376 |
|
2013 |
Karunakaran S, Manji A, Yan CS, Wu ZJ, Clee SM. Moo1 obesity quantitative trait locus in BTBR T+ Itpr3tf/J mice increases food intake. Physiological Genomics. 45: 191-9. PMID 23341217 DOI: 10.1152/Physiolgenomics.00159.2012 |
0.356 |
|
2013 |
Lim GE, Ramshaw HS, Clee SM, Guthridge MA, Lopez AF, Johnson JD. 14-3-3zeta Regulates Adipogenesis, Glucose Tolerance and Insulin Sensitivity in Mice Canadian Journal of Diabetes. 37: S9. DOI: 10.1016/J.Jcjd.2013.08.024 |
0.302 |
|
2013 |
Chan C, Karunakaran S, Lee K, Clee S. Complete Resistance to High Fat Diet-Induced Obesity in WSB/EiJ Mice Canadian Journal of Diabetes. 37: S226. DOI: 10.1016/J.Jcjd.2013.03.078 |
0.349 |
|
2012 |
Mehran AE, Templeman NM, Brigidi GS, Lim GE, Chu KY, Hu X, Botezelli JD, Asadi A, Hoffman BG, Kieffer TJ, Bamji SX, Clee SM, Johnson JD. Hyperinsulinemia drives diet-induced obesity independently of brain insulin production. Cell Metabolism. 16: 723-37. PMID 23217255 DOI: 10.1016/J.Cmet.2012.10.019 |
0.4 |
|
2012 |
Kim SJ, Nian C, Karunakaran S, Clee SM, Isales CM, McIntosh CH. GIP-overexpressing mice demonstrate reduced diet-induced obesity and steatosis, and improved glucose homeostasis. Plos One. 7: e40156. PMID 22802954 DOI: 10.1371/Journal.Pone.0040156 |
0.383 |
|
2012 |
Templeman NM, Mehran AE, Hu X, Clee SM, Johnson JD. Protection Against Diet-Induced Obesity Afforded by Reduced Circulating Insulin Levels is Linked to Increased Energy Expenditure and Browning of White Adipose Canadian Journal of Diabetes. 36: S68. DOI: 10.1016/J.Jcjd.2012.07.438 |
0.348 |
|
2007 |
Goodarzi MO, Lehman DM, Taylor KD, Guo X, Cui J, Quiñones MJ, Clee SM, Yandell BS, Blangero J, Hsueh WA, Attie AD, Stern MP, Rotter JI. SORCS1: a novel human type 2 diabetes susceptibility gene suggested by the mouse. Diabetes. 56: 1922-9. PMID 17426289 DOI: 10.2337/Db06-1677 |
0.337 |
|
2007 |
Clee SM, Attie AD. The genetic landscape of type 2 diabetes in mice. Endocrine Reviews. 28: 48-83. PMID 17018838 DOI: 10.1210/Er.2006-0035 |
0.343 |
|
2006 |
Clee SM, Yandell BS, Schueler KM, Rabaglia ME, Richards OC, Raines SM, Kabara EA, Klass DM, Mui ET, Stapleton DS, Gray-Keller MP, Young MB, Stoehr JP, Lan H, Boronenkov I, et al. Positional cloning of Sorcs1, a type 2 diabetes quantitative trait locus. Nature Genetics. 38: 688-93. PMID 16682971 DOI: 10.1038/Ng1796 |
0.35 |
|
2005 |
Clee SM, Nadler ST, Attie AD. Genetic and genomic studies of the BTBR ob/ob mouse model of type 2 diabetes. American Journal of Therapeutics. 12: 491-8. PMID 16280642 DOI: 10.1097/01.Mjt.0000178781.89789.25 |
0.387 |
|
2004 |
Stoehr JP, Byers JE, Clee SM, Lan H, Boronenkov IV, Schueler KL, Yandell BS, Attie AD. Identification of major quantitative trait loci controlling body weight variation in ob/ob mice. Diabetes. 53: 245-9. PMID 14693723 DOI: 10.2337/Diabetes.53.1.245 |
0.349 |
|
2002 |
Wellington CL, Yang YZ, Zhou S, Clee SM, Tan B, Hirano K, Zwarts K, Kwok A, Gelfer A, Marcil M, Newman S, Roomp K, Singaraja R, Collins J, Zhang LH, et al. Truncation mutations in ABCA1 suppress normal upregulation of full-length ABCA1 by 9-cis-retinoic acid and 22-R-hydroxycholesterol. Journal of Lipid Research. 43: 1939-49. PMID 12401893 DOI: 10.1194/Jlr.M200277-Jlr200 |
0.49 |
|
2002 |
Singaraja RR, Fievet C, Castro G, James ER, Hennuyer N, Clee SM, Bissada N, Choy JC, Fruchart JC, McManus BM, Staels B, Hayden MR. Increased ABCA1 activity protects against atherosclerosis. The Journal of Clinical Investigation. 110: 35-42. PMID 12093886 DOI: 10.1172/Jci15748 |
0.545 |
|
2002 |
Zwarts KY, Clee SM, Zwinderman AH, Engert JC, Singaraja R, Loubser O, James E, Roomp K, Hudson TJ, Jukema JW, Kastelein JJ, Hayden MR. ABCA1 regulatory variants influence coronary artery disease independent of effects on plasma lipid levels. Clinical Genetics. 61: 115-25. PMID 11940086 DOI: 10.1034/J.1399-0004.2002.610206.X |
0.508 |
|
2002 |
van Dam MJ, de Groot E, Clee SM, Hovingh GK, Roelants R, Brooks-Wilson A, Zwinderman AH, Smit AJ, Smelt AH, Groen AK, Hayden MR, Kastelein JJ. Association between increased arterial-wall thickness and impairment in ABCA1-driven cholesterol efflux: an observational study. Lancet (London, England). 359: 37-42. PMID 11809185 DOI: 10.1016/S0140-6736(02)07277-X |
0.546 |
|
2001 |
Clee SM, Loubser O, Collins J, Kastelein JJ, Hayden MR. The LPL S447X cSNP is associated with decreased blood pressure and plasma triglycerides, and reduced risk of coronary artery disease. Clinical Genetics. 60: 293-300. PMID 11683775 DOI: 10.1034/J.1399-0004.2001.600407.X |
0.482 |
|
2001 |
Singaraja RR, Bocher V, James ER, Clee SM, Zhang LH, Leavitt BR, Tan B, Brooks-Wilson A, Kwok A, Bissada N, Yang YZ, Liu G, Tafuri SR, Fievet C, Wellington CL, et al. Human ABCA1 BAC transgenic mice show increased high density lipoprotein cholesterol and ApoAI-dependent efflux stimulated by an internal promoter containing liver X receptor response elements in intron 1. The Journal of Biological Chemistry. 276: 33969-79. PMID 11423537 DOI: 10.1074/Jbc.M102503200 |
0.544 |
|
2001 |
McGladdery SH, Pimstone SN, Clee SM, Bowden JF, Hayden MR, Frohlich JJ. Common mutations in the lipoprotein lipase gene (LPL): effects on HDL-cholesterol levels in a Chinese Canadian population. Atherosclerosis. 156: 401-7. PMID 11395037 DOI: 10.1016/S0021-9150(00)00670-5 |
0.538 |
|
2001 |
Clee SM, Zwinderman AH, Engert JC, Zwarts KY, Molhuizen HO, Roomp K, Jukema JW, van Wijland M, van Dam M, Hudson TJ, Brooks-Wilson A, Genest J, Kastelein JJ, Hayden MR. Common genetic variation in ABCA1 is associated with altered lipoprotein levels and a modified risk for coronary artery disease. Circulation. 103: 1198-205. PMID 11238261 DOI: 10.1161/01.Cir.103.9.1198 |
0.547 |
|
2001 |
Backus RC, Ginzinger DG, Ashbourne Excoffon KJ, Clee SM, Hayden MR, Eckel RH, Hickman MA, Rogers QR. Maternal expression of functional lipoprotein lipase and effects on body fat mass and body condition scores of mature cats with lipoprotein lipase deficiency. American Journal of Veterinary Research. 62: 264-9. PMID 11212037 DOI: 10.2460/Ajvr.2001.62.264 |
0.433 |
|
2000 |
Clee SM, Kastelein JJ, van Dam M, Marcil M, Roomp K, Zwarts KY, Collins JA, Roelants R, Tamasawa N, Stulc T, Suda T, Ceska R, Boucher B, Rondeau C, DeSouich C, et al. Age and residual cholesterol efflux affect HDL cholesterol levels and coronary artery disease in ABCA1 heterozygotes. The Journal of Clinical Investigation. 106: 1263-70. PMID 11086027 DOI: 10.1172/Jci10727 |
0.559 |
|
2000 |
Hayden MR, Clee SM, Brooks-Wilson A, Genest J, Attie A, Kastelein JJ. Cholesterol efflux regulatory protein, Tangier disease and familial high-density lipoprotein deficiency. Current Opinion in Lipidology. 11: 117-22. PMID 10787172 DOI: 10.1097/00041433-200004000-00003 |
0.525 |
|
2000 |
Clee SM, Bissada N, Miao F, Miao L, Marais AD, Henderson HE, Steures P, McManus J, McManus B, LeBoeuf RC, Kastelein JJ, Hayden MR. Plasma and vessel wall lipoprotein lipase have different roles in atherosclerosis. Journal of Lipid Research. 41: 521-31. PMID 10744772 |
0.451 |
|
1999 |
Marcil M, Brooks-Wilson A, Clee SM, Roomp K, Zhang LH, Yu L, Collins JA, van Dam M, Molhuizen HO, Loubster O, Ouellette BF, Sensen CW, Fichter K, Mott S, Denis M, et al. Mutations in the ABC1 gene in familial HDL deficiency with defective cholesterol efflux. Lancet. 354: 1341-6. PMID 10533863 DOI: 10.1016/S0140-6736(99)07026-9 |
0.517 |
|
1999 |
Brooks-Wilson A, Marcil M, Clee SM, Zhang LH, Roomp K, van Dam M, Yu L, Brewer C, Collins JA, Molhuizen HO, Loubser O, Ouelette BF, Fichter K, Ashbourne-Excoffon KJ, Sensen CW, et al. Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency. Nature Genetics. 22: 336-45. PMID 10431236 DOI: 10.1038/11905 |
0.546 |
|
1999 |
Ginzinger DG, Clee SM, Dallongeville J, Lewis ME, Henderson HE, Bauje E, Rogers QR, Jensen DR, Eckel RH, Dyer R, Innis S, Jones B, Fruchart JC, Hayden MR. Lipid and lipoprotein analysis of cats with lipoprotein lipase deficiency. European Journal of Clinical Investigation. 29: 17-26. PMID 10092984 DOI: 10.1046/j.1365-2362.1999.00435.x |
0.474 |
|
1997 |
Ehrenborg E, Clee SM, Pimstone SN, Reymer PW, Benlian P, Hoogendijk CF, Davis HJ, Bissada N, Miao L, Gagné SE, Greenberg LJ, Henry R, Henderson H, Ordovas JM, Schaefer EJ, et al. Ethnic variation and in vivo effects of the -93t-->g promoter variant in the lipoprotein lipase gene. Arteriosclerosis, Thrombosis, and Vascular Biology. 17: 2672-8. PMID 9409241 DOI: 10.1161/01.Atv.17.11.2672 |
0.429 |
|
1997 |
Ginzinger DG, Wilson JE, Redenbach D, Lewis ME, Clee SM, Excoffon KJ, Rogers QR, Hayden MR, McManus BM. Diet-induced atherosclerosis in the domestic cat. Laboratory Investigation; a Journal of Technical Methods and Pathology. 77: 409-19. PMID 9389784 |
0.467 |
|
1997 |
Clee SM, Zhang H, Bissada N, Miao L, Ehrenborg E, Benlian P, Shen GX, Angel A, LeBoeuf RC, Hayden MR. Relationship between lipoprotein lipase and high density lipoprotein cholesterol in mice: modulation by cholesteryl ester transfer protein and dietary status. Journal of Lipid Research. 38: 2079-89. PMID 9374130 |
0.516 |
|
1997 |
Pimstone SN, Defesche JC, Clee SM, Bakker HD, Hayden MR, Kastelein JJ. Differences in the phenotype between children with familial defective apolipoprotein B-100 and familial hypercholesterolemia. Arteriosclerosis, Thrombosis, and Vascular Biology. 17: 826-33. PMID 9157944 DOI: 10.1161/01.Atv.17.5.826 |
0.513 |
|
1996 |
Pimstone SN, Clee SM, Gagné SE, Miao L, Zhang H, Stein EA, Hayden MR. A frequently occurring mutation in the lipoprotein lipase gene (Asn291Ser) results in altered postprandial chylomicron triglyceride and retinyl palmitate response in normolipidemic carriers. Journal of Lipid Research. 37: 1675-84. PMID 8864951 |
0.474 |
|
1996 |
Zhang H, Henderson H, Gagne SE, Clee SM, Miao L, Liu G, Hayden MR. Common sequence variants of lipoprotein lipase: standardized studies of in vitro expression and catalytic function. Biochimica Et Biophysica Acta. 1302: 159-66. PMID 8695666 DOI: 10.1016/0005-2760(96)00059-8 |
0.462 |
|
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