Ryan R. Brinkman, Ph.D. - Publications

2002 University of British Columbia, Vancouver, Vancouver, BC, Canada 
Biostatistics Biology

79 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Bandrowski A, Brinkman R, Brochhausen M, Brush MH, Bug B, Chibucos MC, Clancy K, Courtot M, Derom D, Dumontier M, Fan L, Fostel J, Fragoso G, Gibson F, Gonzalez-Beltran A, et al. The Ontology for Biomedical Investigations. Plos One. 11: e0154556. PMID 27128319 DOI: 10.1371/Journal.Pone.0154556  0.4
2016 Finak G, Langweiler M, Jaimes M, Malek M, Taghiyar J, Korin Y, Raddassi K, Devine L, Obermoser G, Pekalski ML, Pontikos N, Diaz A, Heck S, Villanova F, Terrazzini N, ... ... Brinkman RR, et al. Standardizing Flow Cytometry Immunophenotyping Analysis from the Human ImmunoPhenotyping Consortium. Scientific Reports. 6: 20686. PMID 26861911 DOI: 10.1038/Srep20686  0.4
2016 Brinkman RR, Aghaeepour N, Finak G, Gottardo R, Mosmann T, Scheuermann RH. Automated analysis of flow cytometry data comes of age. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 89: 13-5. PMID 26812230 DOI: 10.1002/Cyto.A.22810  0.4
2016 O'Neill K, Brinkman RR. Publishing code is essential for reproducible flow cytometry bioinformatics. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 89: 10-1. PMID 26812228 DOI: 10.1002/Cyto.A.22805  0.4
2015 Aghaeepour N, Chattopadhyay P, Chikina M, Dhaene T, Van Gassen S, Kursa M, Lambrecht BN, Malek M, Qian Y, Qiu P, Saeys Y, Stanton R, Tong D, Vens C, Walkowiak S, ... ... Brinkman RR, et al. A benchmark for evaluation of algorithms for identification of cellular correlates of clinical outcomes. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. PMID 26447924 DOI: 10.1002/Cyto.A.22732  0.4
2015 Brinkman RR, Aghaeepour N, Finak G, Gottardo R, Mosmann T, Scheuermann RH. State-of-the-Art in the Computational Analysis of Cytometry Data. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 87: 591-3. PMID 26111230 DOI: 10.1002/Cyto.A.22707  0.4
2015 Kvistborg P, Gouttefangeas C, Aghaeepour N, Cazaly A, Chattopadhyay PK, Chan C, Eckl J, Finak G, Hadrup SR, Maecker HT, Maurer D, Mosmann T, Qiu P, Scheuermann RH, Welters MJ, ... ... Brinkman RR, et al. Thinking outside the gate: single-cell assessments in multiple dimensions. Immunity. 42: 591-2. PMID 25902473 DOI: 10.1016/J.Immuni.2015.04.006  0.4
2015 O'Neill K, Aghaeepour N, Parker J, Hogge D, Karsan A, Dalal B, Brinkman RR. Deep profiling of multitube flow cytometry data. Bioinformatics (Oxford, England). 31: 1623-31. PMID 25600947 DOI: 10.1093/Bioinformatics/Btv008  0.4
2015 Courtot M, Meskas J, Diehl AD, Droumeva R, Gottardo R, Jalali A, Taghiyar MJ, Maecker HT, McCoy JP, Ruttenberg A, Scheuermann RH, Brinkman RR. flowCL: ontology-based cell population labelling in flow cytometry. Bioinformatics (Oxford, England). 31: 1337-9. PMID 25481008 DOI: 10.1093/Bioinformatics/Btu807  0.4
2015 Malek M, Taghiyar MJ, Chong L, Finak G, Gottardo R, Brinkman RR. flowDensity: reproducing manual gating of flow cytometry data by automated density-based cell population identification. Bioinformatics (Oxford, England). 31: 606-7. PMID 25378466 DOI: 10.1093/Bioinformatics/Btu677  0.4
2014 Johnstone J, Parsons R, Botelho F, Millar J, McNeil S, Fulop T, McElhaney J, Andrew MK, Walter SD, Devereaux PJ, Malekesmaeili M, Brinkman RR, Mahony J, Bramson J, Loeb M. Immune biomarkers predictive of respiratory viral infection in elderly nursing home residents. Plos One. 9: e108481. PMID 25275464 DOI: 10.1371/Journal.Pone.0108481  0.4
2014 Rothe K, Lin H, Lin KB, Leung A, Wang HM, Malekesmaeili M, Brinkman RR, Forrest DL, Gorski SM, Jiang X. The core autophagy protein ATG4B is a potential biomarker and therapeutic target in CML stem/progenitor cells. Blood. 123: 3622-34. PMID 24755409 DOI: 10.1182/Blood-2013-07-516807  0.4
2014 von Rossum A, Enns W, Shi YP, MacEwan GE, Malekesmaeli M, Brinkman R, Choy JC. Bim regulates alloimmune-mediated vascular injury through effects on T-cell activation and death. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 1290-7. PMID 24700126 DOI: 10.1161/Atvbaha.114.303649  0.4
2014 Courtot M, Brinkman RR, Ruttenberg A. The logic of surveillance guidelines: an analysis of vaccine adverse event reports from an ontological perspective. Plos One. 9: e92632. PMID 24667848 DOI: 10.1371/Journal.Pone.0092632  0.4
2014 O'Neill K, Jalali A, Aghaeepour N, Hoos H, Brinkman RR. Enhanced flowType/RchyOptimyx: a BioConductor pipeline for discovery in high-dimensional cytometry data. Bioinformatics (Oxford, England). 30: 1329-30. PMID 24407226 DOI: 10.1093/Bioinformatics/Btt770  0.4
2014 Craig FE, Brinkman RR, Ten Eyck S, Aghaeepour N. Computational analysis optimizes the flow cytometric evaluation for lymphoma. Cytometry. Part B, Clinical Cytometry. 86: 18-24. PMID 24002786 DOI: 10.1002/Cyto.B.21115  0.4
2014 Aghaeepour N, Brinkman R. Computational analysis of high-dimensional flow cytometric data for diagnosis and discovery. Current Topics in Microbiology and Immunology. 377: 159-75. PMID 23975083 DOI: 10.1007/82_2013_337  0.4
2013 O'Neill K, Aghaeepour N, Spidlen J, Brinkman R. Flow cytometry bioinformatics. Plos Computational Biology. 9: e1003365. PMID 24363631 DOI: 10.1371/Journal.Pcbi.1003365  0.4
2013 Kannan N, Huda N, Tu L, Droumeva R, Aubert G, Chavez E, Brinkman RR, Lansdorp P, Emerman J, Abe S, Eaves C, Gilley D. The luminal progenitor compartment of the normal human mammary gland constitutes a unique site of telomere dysfunction. Stem Cell Reports. 1: 28-37. PMID 24052939 DOI: 10.1016/J.Stemcr.2013.04.003  0.4
2013 Hills M, O'Neill K, Falconer E, Brinkman R, Lansdorp PM. BAIT: Organizing genomes and mapping rearrangements in single cells. Genome Medicine. 5: 82. PMID 24028793 DOI: 10.1186/Gm486  0.4
2013 Villanova F, Di Meglio P, Inokuma M, Aghaeepour N, Perucha E, Mollon J, Nomura L, Hernandez-Fuentes M, Cope A, Prevost AT, Heck S, Maino V, Lord G, Brinkman RR, Nestle FO. Integration of lyoplate based flow cytometry and computational analysis for standardized immunological biomarker discovery. Plos One. 8: e65485. PMID 23843942 DOI: 10.1371/Journal.Pone.0065485  0.4
2013 Spidlen J, Barsky A, Breuer K, Carr P, Nazaire MD, Hill BA, Qian Y, Liefeld T, Reich M, Mesirov JP, Wilkinson P, Scheuermann RH, Sekaly RP, Brinkman RR. GenePattern flow cytometry suite. Source Code For Biology and Medicine. 8: 14. PMID 23822732 DOI: 10.1186/1751-0473-8-14  0.4
2013 Zare H, Haffari G, Gupta A, Brinkman RR. Scoring relevancy of features based on combinatorial analysis of Lasso with application to lymphoma diagnosis. Bmc Genomics. 14: S14. PMID 23369194 DOI: 10.1186/1471-2164-14-S1-S14  0.4
2012 Aghaeepour N, Jalali A, O'Neill K, Chattopadhyay PK, Roederer M, Hoos HH, Brinkman RR. RchyOptimyx: cellular hierarchy optimization for flow cytometry. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 81: 1022-30. PMID 23044634 DOI: 10.1002/Cyto.A.22209  0.4
2012 Streitz M, Fuhrmann S, Thomas D, Cheek E, Nomura L, Maecker H, Martus P, Aghaeepour N, Brinkman RR, Volk HD, Kern F. The phenotypic distribution and functional profile of tuberculin-specific CD4 T-cells characterizes different stages of TB infection. Cytometry. Part B, Clinical Cytometry. 82: 360-8. PMID 22961735 DOI: 10.1002/Cyto.B.21041  0.4
2012 Spidlen J, Breuer K, Rosenberg C, Kotecha N, Brinkman RR. FlowRepository: a resource of annotated flow cytometry datasets associated with peer-reviewed publications. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 81: 727-31. PMID 22887982 DOI: 10.1002/Cyto.A.22106  0.4
2012 Spidlen J, Breuer K, Brinkman R. Preparing a Minimum Information about a Flow Cytometry Experiment (MIFlowCyt) compliant manuscript using the International Society for Advancement of Cytometry (ISAC) FCS file repository (FlowRepository.org). Current Protocols in Cytometry / Editorial Board, J. Paul Robinson, Managing Editor ... [Et Al.]. Unit 10.18. PMID 22752950 DOI: 10.1002/0471142956.Cy1018S61  0.4
2012 Bashashati A, Johnson NA, Khodabakhshi AH, Whiteside MD, Zare H, Scott DW, Lo K, Gottardo R, Brinkman FS, Connors JM, Slack GW, Gascoyne RD, Weng AP, Brinkman RR. B cells with high side scatter parameter by flow cytometry correlate with inferior survival in diffuse large B-cell lymphoma. American Journal of Clinical Pathology. 137: 805-14. PMID 22523221 DOI: 10.1309/Ajcpgr8Bg4Jdvowr  0.4
2012 Benz C, Copley MR, Kent DG, Wohrer S, Cortes A, Aghaeepour N, Ma E, Mader H, Rowe K, Day C, Treloar D, Brinkman RR, Eaves CJ. Hematopoietic stem cell subtypes expand differentially during development and display distinct lymphopoietic programs. Cell Stem Cell. 10: 273-83. PMID 22385655 DOI: 10.1016/J.Stem.2012.02.007  0.4
2012 Aghaeepour N, Chattopadhyay PK, Ganesan A, O'Neill K, Zare H, Jalali A, Hoos HH, Roederer M, Brinkman RR. Early immunologic correlates of HIV protection can be identified from computational analysis of complex multivariate T-cell flow cytometry assays. Bioinformatics (Oxford, England). 28: 1009-16. PMID 22383736 DOI: 10.1093/Bioinformatics/Bts082  0.4
2012 Cheung AM, Leung D, Rostamirad S, Dhillon K, Miller PH, Droumeva R, Brinkman RR, Hogge D, Roy DC, Eaves CJ. Distinct but phenotypically heterogeneous human cell populations produce rapid recovery of platelets and neutrophils after transplantation. Blood. 119: 3431-9. PMID 22374695 DOI: 10.1182/Blood-2011-12-398024  0.4
2012 Bray C, Spidlen J, Brinkman RR. FCS 3.1 Implementation guidance. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 81: 523-6. PMID 22278913 DOI: 10.1002/Cyto.A.22018  0.4
2012 Zare H, Bashashati A, Kridel R, Aghaeepour N, Haffari G, Connors JM, Gascoyne RD, Gupta A, Brinkman RR, Weng AP. Automated analysis of multidimensional flow cytometry data improves diagnostic accuracy between mantle cell lymphoma and small lymphocytic lymphoma. American Journal of Clinical Pathology. 137: 75-85. PMID 22180480 DOI: 10.7490/F1000Research.2134.1  0.4
2011 Spidlen J, Shooshtari P, Kollmann TR, Brinkman RR. Flow cytometry data standards. Bmc Research Notes. 4: 50. PMID 21385382 DOI: 10.1186/1756-0500-4-50  0.4
2011 Aghaeepour N, Nikolic R, Hoos HH, Brinkman RR. Rapid cell population identification in flow cytometry data. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 79: 6-13. PMID 21182178 DOI: 10.1002/Cyto.A.21007  0.4
2011 Courtot M, Gibson F, Lister AL, Malone J, Schober D, Brinkman RR, Ruttenberg A. MIREOT: The minimum information to reference an external ontology term Applied Ontology. 6: 23-33. DOI: 10.3233/Ao-2011-0087  0.4
2011 Rocca-Serra P, Ruttenberg A, O'Connor MJ, Whetzel PL, Schober D, Greenbaum J, Courtot M, Brinkman RR, Sansone SA, Scheuermann R, Peters B. Overcoming the ontology enrichment bottleneck with Quick Term Templates Applied Ontology. 6: 13-22. DOI: 10.3233/Ao-2011-0086  0.4
2010 Zare H, Shooshtari P, Gupta A, Brinkman RR. Data reduction for spectral clustering to analyze high throughput flow cytometry data. Bmc Bioinformatics. 11: 403. PMID 20667133 DOI: 10.1186/1471-2105-11-403  0.4
2010 Shooshtari P, Fortuno ES, Blimkie D, Yu M, Gupta A, Kollmann TR, Brinkman RR. Correlation analysis of intracellular and secreted cytokines via the generalized integrated mean fluorescence intensity. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 77: 873-80. PMID 20629196 DOI: 10.1002/Cyto.A.20943  0.4
2010 Brinkman RR, Courtot M, Derom D, Fostel JM, He Y, Lord P, Malone J, Parkinson H, Peters B, Rocca-Serra P, Ruttenberg A, Sansone SA, Soldatova LN, Stoeckert CJ, Turner JA, et al. Modeling biomedical experimental processes with OBI. Journal of Biomedical Semantics. 1: S7. PMID 20626927 DOI: 10.1186/2041-1480-1-S1-S7  0.4
2010 Jiang X, Forrest D, Nicolini F, Turhan A, Guilhot J, Yip C, Holyoake T, Jorgensen H, Lambie K, Saw KM, Pang E, Vukovic R, Lehn P, Ringrose A, Yu M, ... Brinkman RR, et al. Properties of CD34+ CML stem/progenitor cells that correlate with different clinical responses to imatinib mesylate. Blood. 116: 2112-21. PMID 20574046 DOI: 10.1182/Blood-2009-05-222471  0.4
2010 Xiang Z, Courtot M, Brinkman RR, Ruttenberg A, He Y. OntoFox: web-based support for ontology reuse. Bmc Research Notes. 3: 175. PMID 20569493 DOI: 10.1186/1756-0500-3-175  0.4
2010 Blimkie D, Fortuno ES, Thommai F, Xu L, Fernandes E, Crabtree J, Rein-Weston A, Jansen K, Brinkman RR, Kollmann TR. Identification of B cells through negative gating-An example of the MIFlowCyt standard applied. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 77: 546-51. PMID 20131398 DOI: 10.1002/Cyto.A.20862  0.4
2010 Spidlen J, Moore W, Parks D, Goldberg M, Bray C, Bierre P, Gorombey P, Hyun B, Hubbard M, Lange S, Lefebvre R, Leif R, Novo D, Ostruszka L, Treister A, ... ... Brinkman RR, et al. Data File Standard for Flow Cytometry, version FCS 3.1. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 77: 97-100. PMID 19937951 DOI: 10.1002/Cyto.A.20825  0.4
2010 Hahne F, Khodabakhshi AH, Bashashati A, Wong CJ, Gascoyne RD, Weng AP, Seyfert-Margolis V, Bourcier K, Asare A, Lumley T, Gentleman R, Brinkman RR. Per-channel basis normalization methods for flow cytometry data. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 77: 121-31. PMID 19899135 DOI: 10.1002/Cyto.A.20823  0.4
2009 Qian Y, Tchuvatkina O, Spidlen J, Wilkinson P, Gasparetto M, Jones AR, Manion FJ, Scheuermann RH, Sekaly RP, Brinkman RR. FuGEFlow: data model and markup language for flow cytometry. Bmc Bioinformatics. 10: 184. PMID 19531228 DOI: 10.1186/1471-2105-10-184  0.4
2009 Lo K, Hahne F, Brinkman RR, Gottardo R. flowClust: a Bioconductor package for automated gating of flow cytometry data. Bmc Bioinformatics. 10: 145. PMID 19442304 DOI: 10.1186/1471-2105-10-145  0.4
2009 Vercauteren SM, Bashashati A, Wu D, Brinkman RR, Eaves C, Eaves A, Karsan A. Reduction in multi-lineage and erythroid progenitors distinguishes myelodysplastic syndromes from non-malignant cytopenias. Leukemia Research. 33: 1636-42. PMID 19414193 DOI: 10.1016/J.Leukres.2009.03.019  0.4
2009 Hahne F, LeMeur N, Brinkman RR, Ellis B, Haaland P, Sarkar D, Spidlen J, Strain E, Gentleman R. flowCore: a Bioconductor package for high throughput flow cytometry. Bmc Bioinformatics. 10: 106. PMID 19358741 DOI: 10.1186/1471-2105-10-106  0.4
2009 Johnson NA, Boyle M, Bashashati A, Leach S, Brooks-Wilson A, Sehn LH, Chhanabhai M, Brinkman RR, Connors JM, Weng AP, Gascoyne RD. Diffuse large B-cell lymphoma: reduced CD20 expression is associated with an inferior survival. Blood. 113: 3773-80. PMID 19029441 DOI: 10.1182/Blood-2008-09-177469  0.4
2009 Forrest DL, Trainor S, Brinkman RR, Barnett MJ, Hogge DE, Nevill TJ, Shepherd JD, Nantel SH, Toze CL, Sutherland HJ, Song KW, Lavoie JC, Power MM, Abou-Mourad Y, Smith CA. Cytogenetic and molecular responses to standard-dose imatinib in chronic myeloid leukemia are correlated with Sokal risk scores and duration of therapy but not trough imatinib plasma levels. Leukemia Research. 33: 271-5. PMID 18762338 DOI: 10.1016/J.Leukres.2008.07.015  0.4
2009 Leif RC, Spidlen J, Brinkman RR. A container for the advanced cytometry standard (ACS) Progress in Biomedical Optics and Imaging - Proceedings of Spie. 7182. DOI: 10.1117/12.810195  0.4
2009 Forrest DL, Trainor S, Brinkman RR, Barnett MJ, Hogge DE, Nevill TJ, Shepherd JD, Nantel SH, Toze CL, Sutherland HJ, Song KW, Lavoie JC, Power MM, Abou-Mourad Y, Smith CA. Correlation between trough imatinib plasma concentration and clinical response in chronic myeloid leukemia Leukemia Research. 33: 1149-1150. DOI: 10.1016/J.Leukres.2009.03.002  0.4
2008 Spidlen J, Leif RC, Moore W, Roederer M, Brinkman RR. Gating-ML: XML-based gating descriptions in flow cytometry. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 73: 1151-7. PMID 18773465 DOI: 10.1002/Cyto.A.20637  0.4
2008 Lee JA, Spidlen J, Boyce K, Cai J, Crosbie N, Dalphin M, Furlong J, Gasparetto M, Goldberg M, Goralczyk EM, Hyun B, Jansen K, Kollmann T, Kong M, Leif R, ... ... Brinkman RR, et al. MIFlowCyt: the minimum information about a Flow Cytometry Experiment. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 73: 926-30. PMID 18752282 DOI: 10.1002/Cyto.A.20623  0.4
2008 Ramadan KM, Connors JM, Al-Tourah AJ, Song KW, Gascoyne RD, Barnett MJ, Nevill TJ, Shepherd JD, Nantel SH, Sutherland HJ, Forrest DL, Hogge DE, Lavoie JC, Abou-Mourad YR, Chhanabhai M, ... ... Brinkman RR, et al. Allogeneic SCT for relapsed composite and transformed lymphoma using related and unrelated donors: long-term results. Bone Marrow Transplantation. 42: 601-8. PMID 18695664 DOI: 10.1038/Bmt.2008.220  0.4
2008 Taylor CF, Field D, Sansone SA, Aerts J, Apweiler R, Ashburner M, Ball CA, Binz PA, Bogue M, Booth T, Brazma A, Brinkman RR, Michael Clark A, Deutsch EW, Fiehn O, et al. Promoting coherent minimum reporting guidelines for biological and biomedical investigations: the MIBBI project. Nature Biotechnology. 26: 889-96. PMID 18688244 DOI: 10.1038/Nbt.1411  0.4
2008 Lo K, Brinkman RR, Gottardo R. Automated gating of flow cytometry data via robust model-based clustering. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 73: 321-32. PMID 18307272 DOI: 10.1002/Cyto.A.20531  0.4
2008 Leif RC, Spidlen J, Brinkman RR. Cytometry standards continuum Progress in Biomedical Optics and Imaging - Proceedings of Spie. 6859. DOI: 10.1117/12.762514  0.4
2007 Dykstra B, Kent D, Bowie M, McCaffrey L, Hamilton M, Lyons K, Lee SJ, Brinkman R, Eaves C. Long-term propagation of distinct hematopoietic differentiation programs in vivo. Cell Stem Cell. 1: 218-29. PMID 18371352 DOI: 10.1016/J.Stem.2007.05.015  0.4
2007 Brinkman RR, Gasparetto M, Lee SJ, Ribickas AJ, Perkins J, Janssen W, Smiley R, Smith C. High-content flow cytometry and temporal data analysis for defining a cellular signature of graft-versus-host disease. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 13: 691-700. PMID 17531779 DOI: 10.1016/J.Bbmt.2007.02.002  0.4
2007 Le Meur N, Rossini A, Gasparetto M, Smith C, Brinkman RR, Gentleman R. Data quality assessment of ungated flow cytometry data in high throughput experiments. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 71: 393-403. PMID 17366638 DOI: 10.1002/Cyto.A.20396  0.4
2007 Andresen JM, Gayán J, Djoussé L, Roberts S, Brocklebank D, Cherny SS, Cardon LR, Gusella JF, MacDonald ME, Myers RH, Housman DE, Wexler NS. The relationship between CAG repeat length and age of onset differs for Huntington's disease patients with juvenile onset or adult onset. Annals of Human Genetics. 71: 295-301. PMID 17181545 DOI: 10.1111/J.1469-1809.2006.00335.X  0.4
2006 Spidlen J, Gentleman RC, Haaland PD, Langille M, Le Meur N, Ochs MF, Schmitt C, Smith CA, Treister AS, Brinkman RR. Data standards for flow cytometry. Omics : a Journal of Integrative Biology. 10: 209-14. PMID 16901228 DOI: 10.1089/Omi.2006.10.209  0.4
2006 Whetzel PL, Brinkman RR, Causton HC, Fan L, Field D, Fostel J, Fragoso G, Gray T, Heiskanen M, Hernandez-Boussard T, Morrison N, Parkinson H, Rocca-Serra P, Sansone SA, Schober D, et al. Development of FuGO: an ontology for functional genomics investigations. Omics : a Journal of Integrative Biology. 10: 199-204. PMID 16901226 DOI: 10.1089/Omi.2006.10.199  0.4
2006 Brinkman RR, Dubé MP, Rouleau GA, Orr AC, Samuels ME. Human monogenic disorders - a source of novel drug targets. Nature Reviews. Genetics. 7: 249-60. PMID 16534513 DOI: 10.1038/Nrg1828  0.4
2004 Lafreniere RG, MacDonald ML, Dube MP, MacFarlane J, O'Driscoll M, Brais B, Meilleur S, Brinkman RR, Dadivas O, Pape T, Platon C, Radomski C, Risler J, Thompson J, Guerra-Escobio AM, et al. Identification of a novel gene (HSN2) causing hereditary sensory and autonomic neuropathy type II through the Study of Canadian Genetic Isolates. American Journal of Human Genetics. 74: 1064-73. PMID 15060842 DOI: 10.1086/420795  0.4
2004 Djoussé L, Knowlton B, Hayden MR, Almqvist EW, Brinkman RR, Ross CA, Margolis RL, Rosenblatt A, Durr A, Dode C, Morrison PJ, Novelletto A, Frontali M, Trent RJ, McCusker E, et al. Evidence for a modifier of onset age in Huntington disease linked to the HD gene in 4p16. Neurogenetics. 5: 109-14. PMID 15029481 DOI: 10.1007/S10048-004-0175-2  0.4
2004 Langbehn DR, Brinkman RR, Falush D, Paulsen JS, Hayden MR. A new model for prediction of the age of onset and penetrance for Huntington's disease based on CAG length. Clinical Genetics. 65: 267-77. PMID 15025718 DOI: 10.1111/J.1399-0004.2004.00241.X  0.4
2003 Almqvist EW, Brinkman RR, Wiggins S, Hayden MR. Psychological consequences and predictors of adverse events in the first 5 years after predictive testing for Huntington's disease. Clinical Genetics. 64: 300-9. PMID 12974735 DOI: 10.1034/J.1399-0004.2003.00157.X  0.4
2003 Li JL, Hayden MR, Almqvist EW, Brinkman RR, Durr A, Dodé C, Morrison PJ, Suchowersky O, Ross CA, Margolis RL, Rosenblatt A, Gómez-Tortosa E, Cabrero DM, Novelletto A, Frontali M, et al. A genome scan for modifiers of age at onset in Huntington disease: The HD MAPS study. American Journal of Human Genetics. 73: 682-7. PMID 12900792 DOI: 10.1086/378133  0.4
2003 Djoussé L, Knowlton B, Hayden M, Almqvist EW, Brinkman R, Ross C, Margolis R, Rosenblatt A, Durr A, Dode C, Morrison PJ, Novelletto A, Frontali M, Trent RJ, McCusker E, et al. Interaction of normal and expanded CAG repeat sizes influences age at onset of Huntington disease. American Journal of Medical Genetics. Part A. 119: 279-82. PMID 12784292 DOI: 10.1002/Ajmg.A.20190  0.4
2001 Paulsen JS, Zhao H, Stout JC, Brinkman RR, Guttman M, Ross CA, Como P, Manning C, Hayden MR, Shoulson I. Clinical markers of early disease in persons near onset of Huntington's disease. Neurology. 57: 658-62. PMID 11524475 DOI: 10.1212/Wnl.57.4.658  0.4
2001 Rosenblatt A, Brinkman RR, Liang KY, Almqvist EW, Margolis RL, Huang CY, Sherr M, Franz ML, Abbott MH, Hayden MR, Ross CA. Familial influence on age of onset among siblings with Huntington disease. American Journal of Medical Genetics. 105: 399-403. PMID 11449389 DOI: 10.1002/Ajmg.1400  0.4
1999 Almqvist EW, Bloch M, Brinkman R, Craufurd D, Hayden MR. A worldwide assessment of the frequency of suicide, suicide attempts, or psychiatric hospitalization after predictive testing for Huntington disease. American Journal of Human Genetics. 64: 1293-304. PMID 10205260 DOI: 10.1086/302374  0.4
1999 Hadano S, Nichol K, Brinkman RR, Nasir J, Martindale D, Koop BF, Nicholson DW, Scherer SW, Ikeda JE, Hayden MR. A yeast artificial chromosome-based physical map of the juvenile amyotrophic lateral sclerosis (ALS2) critical region on human chromosome 2q33-q34. Genomics. 55: 106-12. PMID 9889004 DOI: 10.1006/Geno.1998.5637  0.4
1997 Chissoe SL, Marra MA, Hillier L, Brinkman R, Wilson RK, Waterston RH. Representation of cloned genomic sequences in two sequencing vectors: correlation of DNA sequence and subclone distribution. Nucleic Acids Research. 25: 2960-6. PMID 9224593 DOI: 10.1093/Nar/25.15.2960  0.4
1997 Wellington CL, Brinkman RR, O'Kusky JR, Hayden MR. Toward understanding the molecular pathology of Huntington's disease. Brain Pathology (Zurich, Switzerland). 7: 979-1002. PMID 9217979 DOI: 10.1111/J.1750-3639.1997.Tb00897.X  0.4
1997 Brinkman RR, Mezei MM, Theilmann J, Almqvist E, Hayden MR. The likelihood of being affected with Huntington disease by a particular age, for a specific CAG size. American Journal of Human Genetics. 60: 1202-10. PMID 9150168  0.4
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