Jin Zhu, Ph.D. - Publications

Affiliations: 
2002 Indiana University, Bloomington, Bloomington, IN, United States 
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50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Ni S, Li B, Xu Y, Mao F, Li X, Lan L, Zhu J, Li J. Targeting virulence factors as an antimicrobial approach: Pigment inhibitors. Medicinal Research Reviews. PMID 31267561 DOI: 10.1002/med.21621  0.56
2019 Fan L, Qiu XX, Zhu ZY, Lv JL, Lu J, Mao F, Zhu J, Wang JY, Guan XW, Chen J, Ren J, Ye JM, Zhao YH, Li J, Shen X. Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice. Acta Pharmacologica Sinica. PMID 31000769 DOI: 10.1038/s41401-019-0220-1  0.56
2018 Li Z, Tao Y, Wang X, Jiang P, Li J, Peng M, Zhang X, Chen K, Liu H, Zhen P, Zhu J, Liu X, Liu X. Tumor-Secreted Exosomal miR-222 Promotes Tumor Progression via Regulating P27 Expression and Re-Localization in Pancreatic Cancer. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 51: 610-629. PMID 30458449 DOI: 10.1159/000495281  0.56
2018 Bao B, Su P, Zhu J, Chen J, Xu Y, Gu B, Liu Y, Wang L. Rapid aptasensor capable of simply detect tumor markers based on conjugated polyelectrolytes. Talanta. 190: 204-209. PMID 30172500 DOI: 10.1016/j.talanta.2018.07.072  0.32
2018 Xu Y, Zhang J, Wang H, Mao F, Bao K, Liu W, Zhu J, Li X, Zhang H, Li J. Rational Design of Novel Selective Dual-Target Inhibitors of Acetylcholinesterase and Monoamine Oxidase B as Potential anti-Alzheimer's Disease Agents. Acs Chemical Neuroscience. PMID 30110536 DOI: 10.1021/acschemneuro.8b00357  0.56
2018 Li X, Huang Y, Cheng J, Zhang L, Mao F, Zhu J, Sheng C, Li J. Discovery of novel Syk/PDGFR-α/c-Kit inhibitors as multi-targeting drugs to treat rheumatoid arthritis. Bioorganic & Medicinal Chemistry. PMID 30078608 DOI: 10.1016/j.bmc.2018.06.029  0.56
2018 Liu W, Wang H, Li X, Xu Y, Zhang J, Wang W, Gong Q, Qiu X, Zhu J, Mao F, Zhang H, Li J. Design, synthesis and evaluation of vilazodone-tacrine hybrids as multitarget-directed ligands against depression with cognitive impairment. Bioorganic & Medicinal Chemistry. PMID 29729987 DOI: 10.1016/j.bmc.2018.04.037  0.56
2018 Li Z, Yanfang W, Li J, Jiang P, Peng T, Chen K, Zhao X, Zhang Y, Zhen P, Zhu J, Li X. Tumor-released exosomal circular RNA PDE8A promotes invasive growth via the miR-338/MACC1/MET pathway in pancreatic cancer. Cancer Letters. PMID 29709702 DOI: 10.1016/j.canlet.2018.04.035  0.56
2018 Xu LJ, Ma Q, Zhu J, Li J, Xue BX, Gao J, Sun CY, Zang YC, Zhou YB, Yang DR, Shan YX. Combined inhibition of JAK1,2/Stat3‑PD‑L1 signaling pathway suppresses the immune escape of castration‑resistant prostate cancer to NK cells in hypoxia. Molecular Medicine Reports. PMID 29693186 DOI: 10.3892/mmr.2018.8905  0.56
2018 Li Z, Jiang P, Li J, Peng M, Zhao X, Zhang X, Chen K, Zhang Y, Liu H, Gan L, Bi H, Zhen P, Zhu J, Li X. Tumor-derived exosomal lnc-Sox2ot promotes EMT and stemness by acting as a ceRNA in pancreatic ductal adenocarcinoma. Oncogene. PMID 29643475 DOI: 10.1038/s41388-018-0237-9  0.56
2018 Zhang L, Xu LJ, Zhu J, Li J, Xue BX, Gao J, Sun CY, Zang YC, Zhou YB, Yang DR, Shan YX. ATM‑JAK‑PD‑L1 signaling pathway inhibition decreases EMT and metastasis of androgen‑independent prostate cancer. Molecular Medicine Reports. PMID 29568923 DOI: 10.3892/mmr.2018.8781  0.56
2018 Ni S, Li B, Chen F, Wei H, Mao F, Liu Y, Xu Y, Qiu X, Li X, Liu W, Hu L, Ling D, Wang M, Zheng X, Zhu J, et al. Novel Staphyloxanthin Inhibitors with Improved Potency against Multidrug Resistant. Acs Medicinal Chemistry Letters. 9: 233-237. PMID 29541366 DOI: 10.1021/acsmedchemlett.7b00501  0.56
2018 Weng Y, Fan X, Bai Y, Wang S, Huang H, Yang H, Zhu J, Zhang F. promotes lung adenocarcinoma cell growth and metastasis by enhancing fructose utilization. Cell Death Discovery. 4: 38. PMID 29531835 DOI: 10.1038/s41420-018-0038-5  0.32
2018 Li B, Ni S, Chen F, Mao F, Wei H, Liu Y, Zhu J, Lan L, Li J. Discovery of Potent Benzocycloalkane Derived Diapophytoene Desaturase (CrtN) Inhibitors with Enhanced Safety Profile for the Treatment of MRSA, VISA and LRSA Infection. Acs Infectious Diseases. PMID 29377669 DOI: 10.1021/acsinfecdis.7b00259  0.56
2017 Wei H, Mao F, Ni S, Chen F, Li B, Qiu X, Hu L, Wang M, Zheng X, Zhu J, Lan L, Li J. Discovery of novel piperonyl derivatives as diapophytoene desaturase inhibitors for the treatment of methicillin-, vancomycin- and linezolid-resistant Staphylococcus aureus infections. European Journal of Medicinal Chemistry. 145: 235-251. PMID 29328999 DOI: 10.1016/j.ejmech.2017.12.090  0.56
2017 Li B, Ni S, Mao F, Chen F, Liu Y, Wei H, Chen W, Zhu J, Lan L, Li J. Novel Terminal Bipheny-Based Diapophytoene Desaturases (CrtN) Inhibitors as Anti-MRSA/VISR/LRSA Agents with Reduced hERG Activity. Journal of Medicinal Chemistry. PMID 29243920 DOI: 10.1021/acs.jmedchem.7b01300  0.56
2017 Qiu X, Huang Y, Wu D, Mao F, Zhu J, Yan W, Luo HB, Li J. Discovery of novel purine nucleoside derivatives as phosphodiesterase 2 (PDE2) inhibitors: Structure-based virtual screening, optimization and biological evaluation. Bioorganic & Medicinal Chemistry. PMID 29174506 DOI: 10.1016/j.bmc.2017.11.022  0.56
2017 Xu YX, Wang H, Li XK, Dong SN, Liu WW, Gong Q, Wang TD, Tang Y, Zhu J, Li J, Zhang HY, Mao F. Discovery of novel propargylamine-modified 4-aminoalkyl imidazole substituted pyrimidinylthiourea derivatives as multifunctional agents for the treatment of Alzheimer's disease. European Journal of Medicinal Chemistry. 143: 33-47. PMID 29172081 DOI: 10.1016/j.ejmech.2017.08.025  0.56
2017 Chen W, Huang Z, Wang W, Mao F, Guan L, Tang Y, Jiang H, Li J, Huang J, Jiang L, Zhu J. Discovery of new antimalarial agents: Second-generation dual inhibitors against FP-2 and PfDHFR via fragments assembely. Bioorganic & Medicinal Chemistry. PMID 29111368 DOI: 10.1016/j.bmc.2017.10.017  0.56
2017 Zhou Y, Gu P, Li J, Li F, Zhu J, Gao P, Zang Y, Wang Y, Shan Y, Yang D. Suppression of STIM1 inhibits the migration and invasion of human prostate cancer cells and is associated with PI3K/Akt signaling inactivation. Oncology Reports. PMID 29048678 DOI: 10.3892/or.2017.5961  0.56
2017 Ni S, Wei H, Li B, Chen F, Liu Y, Chen W, Xu Y, Qiu X, Li X, Lu Y, Liu W, Hu L, Lin D, Wang M, Zheng X, ... ... Zhu J, et al. Novel Inhibitors of Staphyloxanthin Virulence Factor in Comparison with Linezolid and Vancomycin versus Methicillin-Resistant, Linezolid-Resistant and Vancomycin-Intermediate Staphylococcus aureus Infections in vivo. Journal of Medicinal Chemistry. PMID 28880552 DOI: 10.1021/acs.jmedchem.7b00949  0.56
2017 Li X, Wang H, Xu Y, Liu W, Qiu X, Zhu J, Mao F, Zhang H, Li J. Novel Vilazodone-Tacrine Hybrids as Potential Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease Accompanied with Depression: Design, Synthesis and Biological Evaluation. Acs Chemical Neuroscience. PMID 28872831 DOI: 10.1021/acschemneuro.7b00259  0.56
2017 Madsen KB, Hohwü L, Zhu JL, Olsen J, Obel C. Social selection in cohort studies and later representation of childhood psychiatric diagnoses: The Danish National Birth Cohort. Scandinavian Journal of Public Health. 1403494817726619. PMID 28810815 DOI: 10.1177/1403494817726619  0.56
2017 Guan YB, Yang DR, Nong SJ, Ni J, Hu CH, Li J, Zhu J, Shan YX. Breviscapine (BVP) inhibits prostate cancer progression through damaging DNA by minichromosome maintenance protein-7 (MCM-7) modulation. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 93: 103-116. PMID 28628830 DOI: 10.1016/j.biopha.2017.06.024  0.56
2017 Lu Y, Mao F, Li X, Zheng X, Wang M, Xu Q, Zhu J, Li J. Discovery of Potent, Selective Stem Cell Factor Receptor/Platelet Derived Growth Factor Receptor Alpha (c-KIT/PDGFRα) Dual Inhibitor for the Treatment of Imatinib-Resistant Gastrointestinal Stromal Tumors (GISTs). Journal of Medicinal Chemistry. PMID 28541695 DOI: 10.1021/acs.jmedchem.7b00468  0.56
2017 Liu Y, Xie Z, Zhao D, Zhu J, Mao F, Tang S, Xu H, Luo C, Geng MY, Huang M, Li J. Development of the First Generation of Disulfide-Based Subtype-Selective and Potent Covalent Pyruvate Dehydrogenase Kinase 1 (PDK1) Inhibitors. Journal of Medicinal Chemistry. PMID 28230989 DOI: 10.1021/acs.jmedchem.6b01245  0.56
2016 Lang L, Dong N, Wu D, Yao X, Lu W, Zhang C, Ouyang P, Zhu J, Tang Y, Wang W, Li J, Huang J. 2-Arylbenzo[b]furan derivatives as potent human lipoxygenase inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry. 1-8. PMID 27590167 DOI: 10.1080/14756366.2016.1220376  0.56
2016 Li X, Wang H, Lu Z, Zheng X, Ni W, Zhu J, Fu Y, Lian F, Zhang N, Li J, Zhang H, Mao F. Development of Multifunctional Pyrimidinylthiourea Derivatives as Potential Anti-Alzheimer Agents. Journal of Medicinal Chemistry. PMID 27552582 DOI: 10.1021/acs.jmedchem.6b00636  0.56
2016 Wang Y, Di H, Chen F, Xu Y, Xiao Q, Wang X, Wei H, Lu Y, Zhang L, Zhu J, Lan L, Li J. Discovery of Benzocycloalkane Derivatives Efficiently Blocking Bacterial Virulence for the Treatment of Methicillin-Resistant S. aureus (MRSA) Infections by Targeting Diapophytoene Desaturase (CrtN). Journal of Medicinal Chemistry. PMID 27139780 DOI: 10.1021/acs.jmedchem.6b00122  0.56
2016 Xiao Q, Dong N, Yao X, Wu D, Lu Y, Mao F, Zhu J, Li J, Huang J, Chen A, Huang L, Wang X, Yang G, He G, Xu Y, et al. Bufexamac ameliorates LPS-induced acute lung injury in mice by targeting LTA4H. Scientific Reports. 6: 25298. PMID 27126280 DOI: 10.1038/srep25298  0.56
2016 Wang Y, Chen F, Di H, Xu Y, Xiao Q, Wang X, Wei H, Lu Y, Zhang L, Zhu J, Sheng C, Lan L, Li J. Discovery of Potent Benzofuran Derived Diapophytoene Desaturase (CrtN) Inhibitors with Enhanced Oral Bioavailability for the Treatment of Methicillin-Resistant S. aureus (MRSA) Infections. Journal of Medicinal Chemistry. PMID 26999509 DOI: 10.1021/acs.jmedchem.5b01984  0.56
2016 Xu Y, Liu P, Zheng DH, Wu N, Zhu L, Xing C, Zhu J. Expression profile and prognostic value of NNMT in patients with pancreatic cancer. Oncotarget. PMID 26942567 DOI: 10.18632/oncotarget.7891  0.32
2016 Zhang B, Tran L, Emilsson V, Zhu J. Characterization of Genetic Networks Associated with Alzheimer's Disease. Methods in Molecular Biology (Clifton, N.J.). 1303: 459-77. PMID 26235085 DOI: 10.1007/978-1-4939-2627-5_28  0.52
2015 Yan W, Qing J, Mei H, Nong J, Huang J, Zhu J, Jiang H, Liu L, Zhang L, Li J. Identification, synthesis and pharmacological evaluation of novel anti-EV71 agents via cyclophilin A inhibition. Bioorganic & Medicinal Chemistry Letters. PMID 26564266 DOI: 10.1016/j.bmcl.2015.11.002  0.56
2015 Skowronska-Krawczyk D, Zhao L, Zhu J, Weinreb RN, Cao G, Luo J, Flagg K, Patel S, Wen C, Krupa M, Luo H, Ouyang H, Lin D, Wang W, Li G, ... ... Zhu J, et al. P16INK4a Upregulation Mediated by SIX6 Defines Retinal Ganglion Cell Pathogenesis in Glaucoma. Molecular Cell. PMID 26365380 DOI: 10.1016/j.molcel.2015.07.027  0.32
2015 Bak PL, Midgley N, Zhu JL, Wistoft K, Obel C. The Resilience Program: preliminary evaluation of a mentalization-based education program. Frontiers in Psychology. 6: 753. PMID 26136695 DOI: 10.3389/fpsyg.2015.00753  0.56
2015 Yan W, Qing J, Mei H, Mao F, Huang J, Zhu J, Jiang H, Liu L, Zhang L, Li J. Discovery of Novel Small Molecule Anti-HCV Agents via the CypA Inhibitory Mechanism Using O-Acylation-Directed Lead Optimization. Molecules (Basel, Switzerland). 20: 10342-59. PMID 26053489 DOI: 10.3390/molecules200610342  0.56
2015 Zhang L, Liu W, Mao F, Zhu J, Dong G, Jiang H, Sheng C, Miao L, Huang L, Li J. Discovery of Benzylidene Derivatives as Potent Syk Inhibitors: Synthesis, SAR Analysis, and Biological Evaluation. Archiv Der Pharmazie. PMID 26032727 DOI: 10.1002/ardp.201500096  0.56
2015 Huang H, Si P, Wang L, Xu Y, Xu X, Zhu J, Jiang H, Li W, Chen L, Li J. Design, Synthesis, and Biological Evaluation of Novel Nonsteroidal Farnesoid X Receptor (FXR) Antagonists: Molecular Basis of FXR Antagonism. Chemmedchem. 10: 1184-99. PMID 25982493 DOI: 10.1002/cmdc.201500136  0.56
2015 Lin Z, Li J, Huang Q, Huang Q, Wang Q, Tang L, Gong D, Yang J, Zhu J, Deng J. Chiral surfactant-type catalyst: enantioselective reduction of long-chain aliphatic ketoesters in water. The Journal of Organic Chemistry. 80: 4419-29. PMID 25830366 DOI: 10.1021/acs.joc.5b00241  0.56
2015 Hohwü L, Zhu JL, Graversen L, Li J, Sørensen TI, Obel C. Prenatal parental separation and body weight, including development of overweight and obesity later in childhood. Plos One. 10: e0119138. PMID 25775129 DOI: 10.1371/journal.pone.0119138  0.56
2015 Ma S, Deng J, Li B, Li X, Yan Z, Zhu J, Chen G, Wang Z, Jiang H, Miao L, Li J. Development of second-generation small-molecule RhoA inhibitors with enhanced water solubility, tissue potency, and significant in vivo efficacy. Chemmedchem. 10: 193-206. PMID 25377276 DOI: 10.1002/cmdc.201402386  0.56
2014 Huang H, Xu Y, Zhu J, Li J. Recent advances in non-steroidal FXR antagonists development for therapeutic applications. Current Topics in Medicinal Chemistry. 14: 2175-87. PMID 25388534  0.56
2014 Gu X, Fu M, Ge Z, Zhan F, Ding Y, Ni H, Zhang W, Zhu Y, Tang X, Xiong L, Li J, Qiu L, Mao Y, Zhu J. High expression of MAGE-A9 correlates with unfavorable survival in hepatocellular carcinoma. Scientific Reports. 4: 6625. PMID 25315972 DOI: 10.1038/srep06625  0.56
2014 Liu C, Shi C, Mao F, Xu Y, Liu J, Wei B, Zhu J, Xiang M, Li J. Discovery of new imidazole derivatives containing the 2,4-dienone motif with broad-spectrum antifungal and antibacterial activity. Molecules (Basel, Switzerland). 19: 15653-72. PMID 25268720 DOI: 10.3390/molecules191015653  0.56
2014 Gu X, Fu M, Ding Y, Ni H, Zhang W, Zhu Y, Tang X, Xiong L, Li J, Qiu L, Xu J, Zhu J. TIMP-3 expression associates with malignant behaviors and predicts favorable survival in HCC. Plos One. 9: e106161. PMID 25171061 DOI: 10.1371/journal.pone.0106161  0.56
2014 Zhu JL, Olsen J, Liew Z, Li J, Niclasen J, Obel C. Parental smoking during pregnancy and ADHD in children: the Danish national birth cohort. Pediatrics. 134: e382-8. PMID 25049343 DOI: 10.1542/peds.2014-0213  0.56
2013 Zhang B, Gaiteri C, Bodea LG, Wang Z, McElwee J, Podtelezhnikov AA, Zhang C, Xie T, Tran L, Dobrin R, Fluder E, Clurman B, Melquist S, Narayanan M, Suver C, ... ... Zhu J, et al. Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease. Cell. 153: 707-20. PMID 23622250 DOI: 10.1016/j.cell.2013.03.030  0.52
2013 Liao HX, Lynch R, Zhou T, Gao F, Munir Alam S, Boyd SD, Fire AZ, Roskin KM, Schramm CA, Zhang Z, Zhu J, Shapiro L, Mullikin JC, Gnanakaran S, Hraber P, et al. Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus Nature. 496: 469-476. PMID 23552890 DOI: 10.1038/nature12053  0.52
2011 Tran LM, Zhang B, Zhang Z, Zhang C, Xie T, Lamb JR, Dai H, Schadt EE, Zhu J. Inferring causal genomic alterations in breast cancer using gene expression data. Bmc Systems Biology. 5: 121. PMID 21806811 DOI: 10.1186/1752-0509-5-121  0.52
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