Leonardo Guasti - Publications

Affiliations: 
Queen Mary University of London, London, England, United Kingdom 

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Ruiz-Babot G, Eceiza A, Abollo-Jiménez F, Malyukov M, Carlone DL, Borges K, Da Costa AR, Qarin S, Matsumoto T, Morizane R, Skarnes WC, Ludwig B, Chapple PJ, Guasti L, Storr HL, et al. Generation of glucocorticoid-producing cells derived from human pluripotent stem cells. Cell Reports Methods. 100627. PMID 37924815 DOI: 10.1016/j.crmeth.2023.100627  0.306
2020 Mancini A, Howard SR, Marelli F, Cabrera CP, Barnes MR, Sternberg MJ, Leprovots M, Hadjidemetriou I, Monti E, David A, Wehkalampi K, Oleari R, Lettieri A, Vezzoli V, Vassart G, ... ... Guasti L, et al. LGR4 deficiency results in delayed puberty through impaired Wnt/β-catenin signaling. Jci Insight. 5. PMID 32493844 DOI: 10.1172/Jci.Insight.133434  0.35
2020 Mariniello K, Rognoni E, Guasti L. SUN-LB43 DLK1 Expressing Cells Contribute to the Zonation of the Adrenal Gland Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.2193  0.353
2019 Mariniello K, Ruiz-Babot G, McGaugh EC, Nicholson JG, Gualtieri A, Gaston-Massuet C, Nostro MC, Guasti L. Stem Cells, Self-Renewal, and Lineage Commitment in the Endocrine System. Frontiers in Endocrinology. 10: 772. PMID 31781041 DOI: 10.3389/Fendo.2019.00772  0.328
2019 Hadjidemetriou I, Mariniello K, Ruiz-Babot G, Pittaway J, Mancini A, Mariannis D, Gomez-Sanchez CE, Parvanta L, Drake WM, Chung TT, Abdel-Aziz TE, DiMarco A, Palazzo FF, Wierman ME, Kiseljak-Vassiliades K, ... ... Guasti L, et al. DLK1/PREF1 marks a novel cell population in the human adrenal cortex. The Journal of Steroid Biochemistry and Molecular Biology. 105422. PMID 31265901 DOI: 10.1016/J.Jsbmb.2019.105422  0.339
2019 Novoselova T, King P, Guasti L, Metherell LA, Clark AJL, Chan LF. ACTH signalling and adrenal development: lessons from mouse models. Endocrine Connections. PMID 31189126 DOI: 10.1530/Ec-19-0190  0.419
2019 Maharaj A, Maudhoo A, Chan LF, Novoselova T, Prasad R, Metherell LA, Guasti L. Isolated Glucocorticoid Deficiency: genetic causes and animal models. The Journal of Steroid Biochemistry and Molecular Biology. PMID 30817990 DOI: 10.1016/J.Jsbmb.2019.02.012  0.361
2019 Mancini A, Howard SR, Cabrera CP, Barnes MR, David A, Wehkalampi K, Heger S, Lomniczi A, Guasti L, Ojeda SR, Dunkel L. EAP1 regulation of GnRH promoter activity is important for human pubertal timing. Human Molecular Genetics. PMID 30608578 DOI: 10.1093/Hmg/Ddy451  0.38
2018 Pittaway JFH, Guasti L. Pathobiology and genetics of adrenocortical carcinoma. Journal of Molecular Endocrinology. PMID 30072419 DOI: 10.1530/Jme-18-0122  0.318
2018 Guasti L, New SE, Hadjidemetriou I, Palmiero M, Ferretti P. Plasticity of human adipose-derived stem cells - relevance to tissue repair. The International Journal of Developmental Biology. 62: 431-439. PMID 29938755 DOI: 10.1387/Ijdb.180074Pf  0.326
2018 Novoselova TV, Hussain M, King PJ, Guasti L, Metherell LA, Charalambous M, Clark AJL, Chan LF. MRAP deficiency impairs adrenal progenitor cell differentiation and gland zonation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201701274RR. PMID 29879378 DOI: 10.1096/Fj.201701274Rr  0.393
2018 Balyura M, Gelfgat E, Steenblock C, Androutsellis-Theotokis A, Ruiz-Babot G, Guasti L, Werdermann M, Ludwig B, Bornstein T, Schally AV, Brennand A, Bornstein SR. Expression of progenitor markers is associated with the functionality of a bioartificial adrenal cortex. Plos One. 13: e0194643. PMID 29596439 DOI: 10.1371/Journal.Pone.0194643  0.357
2018 Ruiz-Babot G, Balyura M, Hadjidemetriou I, Ajodha SJ, Taylor DR, Ghataore L, Taylor NF, Schubert U, Ziegler CG, Storr HL, Druce MR, Gevers EF, Drake WM, Srirangalingam U, Conway GS, ... ... Guasti L, et al. Modeling Congenital Adrenal Hyperplasia and Testing Interventions for Adrenal Insufficiency Using Donor-Specific Reprogrammed Cells. Cell Reports. 22: 1236-1249. PMID 29386111 DOI: 10.1016/J.Celrep.2018.01.003  0.381
2017 Poliandri A, Miller D, Howard S, Nobles M, Ruiz-Babot G, Harmer S, Tinker A, McKay T, Guasti L, Dunkel L. Generation of kisspeptin-responsive GnRH neurons from human pluripotent stem cells. Molecular and Cellular Endocrinology. PMID 28232089 DOI: 10.1016/J.Mce.2017.02.030  0.353
2017 Prasad R, Hadjidemetriou I, Maharaj A, Meimaridou E, Buonocore F, Saleem M, Hurcombe J, Bierzynska A, Barbagelata E, Bergadá I, Cassinelli H, Das U, Krone R, Hacihamdioglu B, Sari E, ... ... Guasti L, et al. Sphingosine-1-phosphate lyase mutations cause primary adrenal insufficiency and steroid-resistant nephrotic syndrome. The Journal of Clinical Investigation. PMID 28165343 DOI: 10.1172/Jci90171  0.327
2016 Howard SR, Guasti L, Ruiz-Babot G, Mancini A, David A, Storr HL, Metherell LA, Sternberg MJ, Cabrera CP, Warren HR, Barnes MR, Quinton R, de Roux N, Young J, Guiochon-Mantel A, et al. IGSF10 mutations dysregulate gonadotropin-releasing hormone neuronal migration resulting in delayed puberty. Embo Molecular Medicine. PMID 27137492 DOI: 10.15252/Emmm.201606250  0.353
2016 Novoselova TV, Larder R, Rimmington D, Lelliott C, Wynn E, Gorrigan RJ, Tate P, Guasti L, The Sanger MG, O'Rahilly S, Clark AJ, Logan DW, Coll AP, Chan LF. Loss of Mrap2 is associated with Sim 1 deficiency and increased circulating cholesterol. The Journal of Endocrinology. PMID 27106110 DOI: 10.1530/Joe-16-0057  0.329
2015 Ruiz-Babot G, Hadjidemetriou I, King PJ, Guasti L. New directions for the treatment of adrenal insufficiency. Frontiers in Endocrinology. 6: 70. PMID 25999916 DOI: 10.3389/Fendo.2015.00070  0.303
2013 Yates R, Katugampola H, Cavlan D, Cogger K, Meimaridou E, Hughes C, Metherell L, Guasti L, King P. Adrenocortical development, maintenance, and disease. Current Topics in Developmental Biology. 106: 239-312. PMID 24290352 DOI: 10.1016/B978-0-12-416021-7.00007-9  0.327
2013 Guasti L, Cavlan D, Cogger K, Banu Z, Shakur A, Latif S, King PJ. Dlk1 up-regulates Gli1 expression in male rat adrenal capsule cells through the activation of β1 integrin and ERK1/2. Endocrinology. 154: 4675-84. PMID 24064361 DOI: 10.1210/En.2013-1211  0.384
2013 Guasti L, Candy Sze WC, McKay T, Grose R, King PJ. FGF signalling through Fgfr2 isoform IIIb regulates adrenal cortex development. Molecular and Cellular Endocrinology. 371: 182-8. PMID 23376610 DOI: 10.1016/J.Mce.2013.01.014  0.352
2013 Meimaridou E, Hughes CR, Kowalczyk J, Guasti L, Chapple JP, King PJ, Chan LF, Clark AJ, Metherell LA. Familial glucocorticoid deficiency: New genes and mechanisms. Molecular and Cellular Endocrinology. 371: 195-200. PMID 23279877 DOI: 10.1016/J.Mce.2012.12.010  0.36
2012 Guasti L, Prasongchean W, Kleftouris G, Mukherjee S, Thrasher AJ, Bulstrode NW, Ferretti P. High plasticity of pediatric adipose tissue-derived stem cells: too much for selective skeletogenic differentiation? Stem Cells Translational Medicine. 1: 384-95. PMID 23197817 DOI: 10.5966/Sctm.2012-0009  0.303
2012 Hughes CR, Guasti L, Meimaridou E, Chuang CH, Schimenti JC, King PJ, Costigan C, Clark AJ, Metherell LA. MCM4 mutation causes adrenal failure, short stature, and natural killer cell deficiency in humans. The Journal of Clinical Investigation. 122: 814-20. PMID 22354170 DOI: 10.1172/Jci60224  0.356
2012 Kowalczyk J, Meimaridou E, Guasti L, Lei XG, Clark AJL, Metherell LA. A homozygous glutathione peroxidase 1 mutation, p. Arg130-Leu133del, in a patient with familial glucocorticoid deficiency Free Radical Biology and Medicine. 53. DOI: 10.1016/J.Freeradbiomed.2012.08.462  0.3
2011 Cooray SN, Guasti L, Clark AJ. The E3 ubiquitin ligase Mahogunin ubiquitinates the melanocortin 2 receptor. Endocrinology. 152: 4224-31. PMID 21862608 DOI: 10.1210/En.2011-0147  0.374
2011 Gorrigan RJ, Guasti L, King P, Clark AJ, Chan LF. Localisation of the melanocortin-2-receptor and its accessory proteins in the developing and adult adrenal gland. Journal of Molecular Endocrinology. 46: 227-32. PMID 21367968 DOI: 10.1530/Jme-11-0011  0.43
2011 Guasti L, Paul A, Laufer E, King P. Localization of Sonic hedgehog secreting and receiving cells in the developing and adult rat adrenal cortex. Molecular and Cellular Endocrinology. 336: 117-22. PMID 21094676 DOI: 10.1016/J.Mce.2010.11.010  0.352
2010 Igreja S, Chahal HS, King P, Bolger GB, Srirangalingam U, Guasti L, Chapple JP, Trivellin G, Gueorguiev M, Guegan K, Stals K, Khoo B, Kumar AV, Ellard S, Grossman AB, et al. Characterization of aryl hydrocarbon receptor interacting protein (AIP) mutations in familial isolated pituitary adenoma families. Human Mutation. 31: 950-60. PMID 20506337 DOI: 10.1002/Humu.21292  0.36
2009 Guasti L, Richardson D, Jhaveri M, Eldeeb K, Barrett D, Elphick MR, Alexander SP, Kendall D, Michael GJ, Chapman V. Minocycline treatment inhibits microglial activation and alters spinal levels of endocannabinoids in a rat model of neuropathic pain. Molecular Pain. 5: 35. PMID 19570201 DOI: 10.1186/1744-8069-5-35  0.504
2009 Chan LF, Webb TR, Chung TT, Meimaridou E, Cooray SN, Guasti L, Chapple JP, Egertová M, Elphick MR, Cheetham ME, Metherell LA, Clark AJ. MRAP and MRAP2 are bidirectional regulators of the melanocortin receptor family. Proceedings of the National Academy of Sciences of the United States of America. 106: 6146-51. PMID 19329486 DOI: 10.1073/Pnas.0809918106  0.655
2008 Guasti L, Crociani O, Redaelli E, Pillozzi S, Polvani S, Masselli M, Mello T, Galli A, Amedei A, Wymore RS, Wanke E, Arcangeli A. Identification of a posttranslational mechanism for the regulation of hERG1 K+ channel expression and hERG1 current density in tumor cells. Molecular and Cellular Biology. 28: 5043-60. PMID 18559421 DOI: 10.1128/Mcb.00304-08  0.358
2008 King PJ, Guasti L, Laufer E. Hedgehog signalling in endocrine development and disease. The Journal of Endocrinology. 198: 439-50. PMID 18524957 DOI: 10.1677/Joe-08-0161  0.312
2006 Restano-Cassulini R, Korolkova YV, Diochot S, Gurrola G, Guasti L, Possani LD, Lazdunski M, Grishin EV, Arcangeli A, Wanke E. Species diversity and peptide toxins blocking selectivity of ether-a-go-go-related gene subfamily K+ channels in the central nervous system. Molecular Pharmacology. 69: 1673-83. PMID 16497878 DOI: 10.1124/Mol.105.019729  0.3
2005 Furlan F, Guasti L, Avossa D, Becchetti A, Cilia E, Ballerini L, Arcangeli A. Interneurons transiently express the ERG K+ channels during development of mouse spinal networks in vitro. Neuroscience. 135: 1179-92. PMID 16165280 DOI: 10.1016/J.Neuroscience.2005.06.040  0.335
2005 Guasti L, Cilia E, Crociani O, Hofmann G, Polvani S, Becchetti A, Wanke E, Tempia F, Arcangeli A. Expression pattern of the ether-a-go-go-related (ERG) family proteins in the adult mouse central nervous system: evidence for coassembly of different subunits. The Journal of Comparative Neurology. 491: 157-74. PMID 16127690 DOI: 10.1002/Cne.20721  0.338
2005 Cherubini A, Hofmann G, Pillozzi S, Guasti L, Crociani O, Cilia E, Di Stefano P, Degani S, Balzi M, Olivotto M, Wanke E, Becchetti A, Defilippi P, Wymore R, Arcangeli A. Human ether-a-go-go-related gene 1 channels are physically linked to beta1 integrins and modulate adhesion-dependent signaling. Molecular Biology of the Cell. 16: 2972-83. PMID 15800067 DOI: 10.1091/Mbc.E04-10-0940  0.357
2004 Arcangeli A, Becchetti A, Cherubini A, Crociani O, Defilippi P, Guasti L, Hofmann G, Pillozzi S, Olivotto M, Wanke E. Physical and functional interaction between integrins and hERG potassium channels. Biochemical Society Transactions. 32: 826-7. PMID 15494025 DOI: 10.1042/Bst0320826  0.345
2004 Lastraioli E, Guasti L, Crociani O, Polvani S, Hofmann G, Witchel H, Bencini L, Calistri M, Messerini L, Scatizzi M, Moretti R, Wanke E, Olivotto M, Mugnai G, Arcangeli A. herg1 gene and HERG1 protein are overexpressed in colorectal cancers and regulate cell invasion of tumor cells. Cancer Research. 64: 606-11. PMID 14744775 DOI: 10.1158/0008-5472.Can-03-2360  0.312
2003 Gullo F, Ales E, Rosati B, Lecchi M, Masi A, Guasti L, Cano-Abad MF, Arcangeli A, Lopez MG, Wanke E. ERG K+ channel blockade enhances firing and epinephrine secretion in rat chromaffin cells: the missing link to LQT2-related sudden death? Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 330-2. PMID 12490549 DOI: 10.1096/Fj.02-0200Fje  0.348
2003 Crociani O, Guasti L, Balzi M, Becchetti A, Wanke E, Olivotto M, Wymore RS, Arcangeli A. Cell cycle-dependent expression of HERG1 and HERG1B isoforms in tumor cells. The Journal of Biological Chemistry. 278: 2947-55. PMID 12431979 DOI: 10.1074/Jbc.M210789200  0.35
2002 Pillozzi S, Brizzi MF, Balzi M, Crociani O, Cherubini A, Guasti L, Bartolozzi B, Becchetti A, Wanke E, Bernabei PA, Olivotto M, Pegoraro L, Arcangeli A. HERG potassium channels are constitutively expressed in primary human acute myeloid leukemias and regulate cell proliferation of normal and leukemic hemopoietic progenitors. Leukemia. 16: 1791-8. PMID 12200695 DOI: 10.1038/Sj.Leu.2402572  0.355
2001 Hofmann G, Bernabei PA, Crociani O, Cherubini A, Guasti L, Pillozzi S, Lastraioli E, Polvani S, Bartolozzi B, Solazzo V, Gragnani L, Defilippi P, Rosati B, Wanke E, Olivotto M, et al. HERG K+ channels activation during beta(1) integrin-mediated adhesion to fibronectin induces an up-regulation of alpha(v)beta(3) integrin in the preosteoclastic leukemia cell line FLG 29.1. The Journal of Biological Chemistry. 276: 4923-31. PMID 11080495 DOI: 10.1074/Jbc.M005682200  0.404
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