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Kai Tan - Publications

Affiliations: 
University of Iowa, Iowa City, IA 
Website:
http://www.medicine.uiowa.edu/Labs/Tan/
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50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Hsu J, Huang HT, Lee CT, Choudhuri A, Wilson NK, Abraham BJ, Moignard V, Kucinski I, Yu S, Hyde RK, Tober J, Cai X, Li Y, Guo Y, Yang S, ... ... Tan K, et al. CHD7 and Runx1 interaction provides a braking mechanism for hematopoietic differentiation. Proceedings of the National Academy of Sciences of the United States of America. PMID 32883883 DOI: 10.1073/Pnas.2003228117  0.397
2020 Gao P, Chen C, Howell ED, Li Y, Tober J, Uzun Y, He B, Gao L, Zhu Q, Siekmann AF, Speck NA, Tan K. Transcriptional regulatory network controlling the ontogeny of hematopoietic stem cells. Genes & Development. PMID 32499402 DOI: 10.1101/Gad.338202.120  0.413
2020 Zhu Q, Gao P, Tober J, Bennett L, Chen C, Uzun Y, Li Y, Howell ED, Mumau M, Yu W, He B, Speck NA, Tan K. Developmental trajectory of pre-hematopoietic stem cell formation from endothelium. Blood. PMID 32392346 DOI: 10.1182/Blood.2020004801  0.346
2019 Chen C, Yu W, Tober J, Gao P, He B, Lee K, Trieu T, Blobel GA, Speck NA, Tan K. Spatial Genome Re-organization between Fetal and Adult Hematopoietic Stem Cells. Cell Reports. 29: 4200-4211.e7. PMID 31851943 DOI: 10.1016/J.Celrep.2019.11.065  0.365
2019 Packer JS, Zhu Q, Huynh C, Sivaramakrishnan P, Preston E, Dueck H, Stefanik D, Tan K, Trapnell C, Kim J, Waterston RH, Murray JI. A lineage-resolved molecular atlas of embryogenesis at single-cell resolution. Science (New York, N.Y.). PMID 31488706 DOI: 10.1126/Science.Aax1971  0.334
2019 Hu Y, Chen CH, Ding YY, Wen X, Wang B, Gao L, Tan K. Optimal control nodes in disease-perturbed networks as targets for combination therapy. Nature Communications. 10: 2180. PMID 31097707 DOI: 10.1038/S41467-019-10215-Y  0.354
2019 Peng T, Zhu Q, Yin P, Tan K. SCRABBLE: single-cell RNA-seq imputation constrained by bulk RNA-seq data. Genome Biology. 20: 88. PMID 31060596 DOI: 10.1186/S13059-019-1681-8  0.327
2019 Taylor DM, Aronow BJ, Tan K, Bernt K, Salomonis N, Greene CS, Frolova A, Henrickson SE, Wells A, Pei L, Jaiswal JK, Whitsett J, Hamilton KE, MacParland SA, Kelsen J, et al. The Pediatric Cell Atlas: Defining the Growth Phase of Human Development at Single-Cell Resolution. Developmental Cell. PMID 30930166 DOI: 10.1016/J.Devcel.2019.03.001  0.358
2019 Nicetto D, Donahue G, Jain T, Peng T, Sidoli S, Sheng L, Montavon T, Becker JS, Grindheim JM, Blahnik K, Garcia BA, Tan K, Bonasio R, Jenuwein T, Zaret KS. H3K9me3-heterochromatin loss at protein-coding genes enables developmental lineage specification. Science (New York, N.Y.). PMID 30606806 DOI: 10.1126/Science.Aau0583  0.377
2019 Estevez B, Borst S, Jarocha DJ, Sudunagunta V, Gonzalez M, Gao P, Tan K, French DL, Gadue P, Poncz M. The Inherited Platelet Disorder of RUNX1 Haploinsufficiency (Familial Platelet Disorder with Associated Myeloid Malignancy (FPDMM)) Has a Marked Deficiency of Megakaryocyte-Biased Hematopoietic Progenitor Cells: Mechanistic Studies and Drug Correction Blood. 134: 220-220. DOI: 10.1182/Blood-2019-124851  0.354
2019 Speck N, Zhu Q, Gao P, Tober J, Bennett L, Chen C, Uzun Y, Li Y, Tan K. Developmental Biology of the Blood System Blood. 134: SCI-29-SCI-29. DOI: 10.1182/Blood-2019-121283  0.328
2019 Howell E, He B, Lakadamyali M, Speck N, Tan K, Gao P, Yzaguirre A. 2010 - IDENTIFYING NECESSARY CHROMATIN STATES AND TARGETS FOR HEMOGENIC SPECIFICATION AND REPROGRAMMING Experimental Hematology. 76: S45. DOI: 10.1016/J.Exphem.2019.06.284  0.353
2018 Gao L, Tober J, Gao P, Chen C, Zhu Q, Tan K, Speck NA. RUNX1 and the endothelial origin of blood. Experimental Hematology. PMID 30391350 DOI: 10.1016/J.Exphem.2018.10.009  0.362
2018 Behera V, Evans P, Face CJ, Hamagami N, Sankaranarayanan L, Keller CA, Giardine B, Tan K, Hardison RC, Shi J, Blobel GA. Exploiting genetic variation to uncover rules of transcription factor binding and chromatin accessibility. Nature Communications. 9: 782. PMID 29472540 DOI: 10.1038/S41467-018-03082-6  0.356
2018 Gao L, Uzun Y, Gao P, He B, Ma X, Wang J, Han S, Tan K. Identifying noncoding risk variants using disease-relevant gene regulatory networks. Nature Communications. 9: 702. PMID 29453388 DOI: 10.1038/S41467-018-03133-Y  0.328
2018 He B, Gao P, Ding Y, Chen C, Kim H, Hunger SP, Tasian SK, Tan K. Abstract 2280: Systematic analysis of causal noncoding mutations in pediatric B-cell acute lymphoblastic leukemia Cancer Research. 78: 2280-2280. DOI: 10.1158/1538-7445.Am2018-2280  0.308
2017 Yu W, He B, Tan K. Identifying topologically associating domains and subdomains by Gaussian Mixture model And Proportion test. Nature Communications. 8: 535. PMID 28912419 DOI: 10.1038/S41467-017-00478-8  0.328
2017 Li F, He B, Ma X, Yu S, Bhave RR, Lentz SR, Tan K, Guzman ML, Zhao C, Xue HH. Prostaglandin E1 and Its Analog Misoprostol Inhibit Human CML Stem Cell Self-Renewal via EP4 Receptor Activation and Repression of AP-1. Cell Stem Cell. PMID 28844837 DOI: 10.1016/J.Stem.2017.08.001  0.329
2017 Li Y, Gao L, Hadland B, Tan K, Speck NA. CD27 marks murine embryonic hematopoietic stem cells and type II pre-hematopoietic stem cells. Blood. PMID 28588017 DOI: 10.1182/Blood-2017-03-776849  0.309
2016 He B, Xing S, Chen C, Gao P, Teng L, Shan Q, Gullicksrud JA, Martin MD, Yu S, Harty JT, Badovinac VP, Tan K, Xue HH. CD8(+) T Cells Utilize Highly Dynamic Enhancer Repertoires and Regulatory Circuitry in Response to Infections. Immunity. PMID 27986453 DOI: 10.1016/J.Immuni.2016.11.009  0.353
2016 Teng L, He B, Wang J, Tan K. 4DGenome: a comprehensive database of chromatin interactions. Bioinformatics (Oxford, England). PMID 27371723 DOI: 10.1093/Bioinformatics/Btw375  0.31
2016 He B, Tan K. Understanding transcriptional regulatory networks using computational models. Current Opinion in Genetics & Development. 37: 101-108. PMID 26950762 DOI: 10.1016/J.Gde.2016.02.002  0.318
2016 Holmfeldt P, Ganuza M, Marathe H, He B, Hall T, Kang G, Moen J, Pardieck J, Saulsberry AC, Cico A, Gaut L, McGoldrick D, Finkelstein D, Tan K, McKinney-Freeman S. Functional screen identifies regulators of murine hematopoietic stem cell repopulation. The Journal of Experimental Medicine. PMID 26880577 DOI: 10.1084/Jem.20150806  0.376
2016 Huang J, Wang K, Wei P, Liu X, Liu X, Tan K, Boerwinkle E, Potash JB, Han S. FLAGS: A Flexible and Adaptive Association Test for Gene Sets Using Summary Statistics. Genetics. PMID 26773050 DOI: 10.1534/Genetics.115.185009  0.302
2015 Cao Z, Chen C, He B, Tan K, Lu C. A microfluidic device for epigenomic profiling using 100 cells. Nature Methods. PMID 26214128 DOI: 10.1038/Nmeth.3488  0.336
2015 Cai X, Gao L, Teng L, Ge J, Oo ZM, Kumar AR, Gilliland DG, Mason PJ, Tan K, Speck NA. Runx1 Deficiency Decreases Ribosome Biogenesis and Confers Stress Resistance to Hematopoietic Stem and Progenitor Cells. Cell Stem Cell. 17: 165-77. PMID 26165925 DOI: 10.1016/J.Stem.2015.06.002  0.331
2015 Ma X, Gao L, Karamanlidis G, Gao P, Lee CF, Garcia-Menendez L, Tian R, Tan K. Revealing Pathway Dynamics in Heart Diseases by Analyzing Multiple Differential Networks. Plos Computational Biology. 11: e1004332. PMID 26083688 DOI: 10.1371/Journal.Pcbi.1004332  0.327
2014 Li Y, Esain V, Teng L, Xu J, Kwan W, Frost IM, Yzaguirre AD, Cai X, Cortes M, Maijenburg MW, Tober J, Dzierzak E, Orkin SH, Tan K, North TE, et al. Inflammatory signaling regulates embryonic hematopoietic stem and progenitor cell production. Genes & Development. 28: 2597-612. PMID 25395663 DOI: 10.1101/Gad.253302.114  0.348
2014 He B, Chen C, Teng L, Tan K. Global view of enhancer-promoter interactome in human cells. Proceedings of the National Academy of Sciences of the United States of America. 111: E2191-9. PMID 24821768 DOI: 10.1073/Pnas.1320308111  0.352
2014 Teng L, He B, Gao P, Gao L, Tan K. Discover context-specific combinatorial transcription factor interactions by integrating diverse ChIP-Seq data sets. Nucleic Acids Research. 42: e24. PMID 24217919 DOI: 10.1093/Nar/Gkt1105  0.382
2014 Li Y, Esain V, Teng L, Xu J, Frost I, Kwan W, Yzaguirre AD, Maijenberg MW, Orkin SH, Tan K, North TE, Speck NA. Inflammatory Signaling Regulates Embryonic Hematopoietic Stem and Lymphoid Progenitor Cell Formation Blood. 124: 2902-2902. DOI: 10.1182/Blood.V124.21.2902.2902  0.352
2013 Soshnev AA, Baxley RM, Manak JR, Tan K, Geyer PK. The insulator protein Suppressor of Hairy-wing is an essential transcriptional repressor in the Drosophila ovary. Development (Cambridge, England). 140: 3613-23. PMID 23884443 DOI: 10.1242/Dev.094953  0.365
2012 Kim J, Gao L, Tan K. Multi-analyte network markers for tumor prognosis. Plos One. 7: e52973. PMID 23300836 DOI: 10.1371/Journal.Pone.0052973  0.338
2012 Teng L, Tan K. Finding combinatorial histone code by semi-supervised biclustering. Bmc Genomics. 13: 301. PMID 22759587 DOI: 10.1186/1471-2164-13-301  0.324
2012 Fan R, Bonde S, Gao P, Sotomayor B, Chen C, Mouw T, Zavazava N, Tan K. Dynamic HoxB4-regulatory network during embryonic stem cell differentiation to hematopoietic cells. Blood. 119: e139-47. PMID 22438249 DOI: 10.1182/Blood-2011-12-396754  0.422
2012 Soshnev AA, He B, Baxley RM, Jiang N, Hart CM, Tan K, Geyer PK. Genome-wide studies of the multi-zinc finger Drosophila Suppressor of Hairy-wing protein in the ovary. Nucleic Acids Research. 40: 5415-31. PMID 22406832 DOI: 10.1093/Nar/Gks225  0.339
2011 Teng L, Firpi HA, Tan K. Enhancers in embryonic stem cells are enriched for transposable elements and genetic variations associated with cancers. Nucleic Acids Research. 39: 7371-9. PMID 21685454 DOI: 10.1093/Nar/Gkr476  0.382
2011 Ucar D, Hu Q, Tan K. Combinatorial chromatin modification patterns in the human genome revealed by subspace clustering. Nucleic Acids Research. 39: 4063-75. PMID 21266477 DOI: 10.1093/Nar/Gkr016  0.343
2010 Kuo D, Licon K, Bandyopadhyay S, Chuang R, Luo C, Catalana J, Ravasi T, Tan K, Ideker T. Coevolution within a transcriptional network by compensatory trans and cis mutations. Genome Research. 20: 1672-8. PMID 20978140 DOI: 10.1101/Gr.111765.110  0.618
2010 Kuo D, Tan K, Zinman G, Ravasi T, Bar-Joseph Z, Ideker T. Evolutionary divergence in the fungal response to fluconazole revealed by soft clustering. Genome Biology. 11: R77. PMID 20653936 DOI: 10.1186/Gb-2010-11-7-R77  0.499
2010 Firpi HA, Ucar D, Tan K. Discover regulatory DNA elements using chromatin signatures and artificial neural network. Bioinformatics (Oxford, England). 26: 1579-86. PMID 20453004 DOI: 10.1093/Bioinformatics/Btq248  0.339
2010 Ravasi T, Suzuki H, Cannistraci CV, Katayama S, Bajic VB, Tan K, Akalin A, Schmeier S, Kanamori-Katayama M, Bertin N, Carninci P, Daub CO, Forrest AR, Gough J, Grimmond S, et al. An atlas of combinatorial transcriptional regulation in mouse and man. Cell. 140: 744-52. PMID 20211142 DOI: 10.1016/J.Cell.2010.01.044  0.563
2009 Suzuki H, Forrest AR, van Nimwegen E, Daub CO, Balwierz PJ, Irvine KM, Lassmann T, Ravasi T, Hasegawa Y, de Hoon MJ, Katayama S, Schroder K, Carninci P, Tomaru Y, ... ... Tan K, et al. The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line. Nature Genetics. 41: 553-62. PMID 19377474 DOI: 10.1038/Ng.375  0.405
2008 Tan K, Feizi H, Luo C, Fan SH, Ravasi T, Ideker TG. A systems approach to delineate functions of paralogous transcription factors: role of the Yap family in the DNA damage response. Proceedings of the National Academy of Sciences of the United States of America. 105: 2934-9. PMID 18287073 DOI: 10.1073/Pnas.0708670105  0.566
2008 Tan K, Tegner J, Ravasi T. Integrated approaches to uncovering transcription regulatory networks in mammalian cells. Genomics. 91: 219-31. PMID 18191937 DOI: 10.1016/J.Ygeno.2007.11.005  0.351
2007 Tan K, Shlomi T, Feizi H, Ideker T, Sharan R. Transcriptional regulation of protein complexes within and across species. Proceedings of the National Academy of Sciences of the United States of America. 104: 1283-8. PMID 17227853 DOI: 10.1073/Pnas.0606914104  0.544
2005 Tan K, McCue LA, Stormo GD. Making connections between novel transcription factors and their DNA motifs. Genome Research. 15: 312-20. PMID 15653829 DOI: 10.1101/Gr.3069205  0.342
2003 Liu J, Tan K, Stormo GD. Computational identification of the Spo0A-phosphate regulon that is essential for the cellular differentiation and development in Gram-positive spore-forming bacteria. Nucleic Acids Research. 31: 6891-903. PMID 14627822 DOI: 10.1093/Nar/Gkg879  0.364
2002 Stormo GD, Tan K. Mining genome databases to identify and understand new gene regulatory systems. Current Opinion in Microbiology. 5: 149-53. PMID 11934610 DOI: 10.1016/S1369-5274(02)00309-0  0.332
2001 Tan K, Moreno-Hagelsieb G, Collado-Vides J, Stormo GD. A comparative genomics approach to prediction of new members of regulons Genome Research. 11: 566-584. PMID 11282972 DOI: 10.1101/Gr.149301  0.355
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