Theodore G. Wensel, PhD - Publications

Affiliations: 
1988- Biochemistry and Molecular Biology Baylor College of Medicine, Houston, TX 
Area:
retina, TRP channels, RGS proteins, GPCR (dopamine, mGluR),fluorescence spectroscopy and microscopy, lanthanide luminscence, cryo-EM
Website:
http://ncmi.bcm.edu/homes/wensellab

137 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Zhang Z, Moye AR, He F, Chen M, Agosto MA, Wensel TG. Centriole and transition zone structures in photoreceptor cilia revealed by cryo-electron tomography. Life Science Alliance. 7. PMID 38182160 DOI: 10.26508/lsa.202302409  0.717
2023 Moye AR, Robichaux MA, Wensel T. Correction to: Expansion Microscopy of Mouse Photoreceptor Cilia. Advances in Experimental Medicine and Biology. 1415: C1. PMID 37656405 DOI: 10.1007/978-3-031-27681-1_85  0.733
2023 Moyel AR, Robichaux MA, Wensel T. Expansion Microscopy of Mouse Photoreceptor Cilia. Advances in Experimental Medicine and Biology. 1415: 395-402. PMID 37440063 DOI: 10.1007/978-3-031-27681-1_58  0.726
2023 Konecki DM, Hamrick S, Wang C, Agosto MA, Wensel TG, Lichtarge O. CovET: A Covariation-Evolutionary Trace method that Identifies Protein Structure-Function Modules. The Journal of Biological Chemistry. 104896. PMID 37290531 DOI: 10.1016/j.jbc.2023.104896  0.713
2023 Huh E, Agosto MA, Wensel TG, Lichtarge O. Co-evolutionary Signals in Metabotropic Glutamate Receptors Capture Residue Contacts and Long-Range Functional Interactions. The Journal of Biological Chemistry. 103030. PMID 36806686 DOI: 10.1016/j.jbc.2023.103030  0.714
2022 Robichaux MA, Nguyen V, Chan F, Kailasam L, He F, Wilson JH, Wensel TG. Subcellular localization of mutant P23H rhodopsin in an RFP fusion knockin mouse model of retinitis pigmentosa. Disease Models & Mechanisms. PMID 35275162 DOI: 10.1242/dmm.049336  0.758
2021 Huh E, Gallion J, Agosto MA, Wright SJ, Wensel TG, Lichtarge O. Recurrent high-impact mutations at cognate structural positions in class A G protein-coupled receptors expressed in tumors. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34916293 DOI: 10.1073/pnas.2113373118  0.711
2021 Agosto MA, Adeosun AAR, Kumar N, Wensel TG. The mGluR6 ligand-binding domain, but not the C-terminal domain, is required for synaptic localization in retinal ON-bipolar cells. The Journal of Biological Chemistry. 101418. PMID 34793838 DOI: 10.1016/j.jbc.2021.101418  0.723
2021 Potter VL, Moye AR, Robichaux MA, Wensel TG. Superresolution microscopy reveals photoreceptor-specific subciliary location and function of ciliopathy-associated protein, Cep290. Jci Insight. PMID 34520396 DOI: 10.1172/jci.insight.145256  0.77
2021 Wensel TG, Potter VL, Moye A, Zhang Z, Robichaux MA. Structure and dynamics of photoreceptor sensory cilia. Pflugers Archiv : European Journal of Physiology. PMID 34050409 DOI: 10.1007/s00424-021-02564-9  0.753
2020 Go YM, Zhang J, Fernandes J, Litwin C, Chen R, Wensel TG, Jones DP, Cai J, Chen Y. MTOR-initiated metabolic switch and degeneration in the retinal pigment epithelium. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32721041 DOI: 10.1096/Fj.202000612R  0.354
2020 Agosto MA, Wensel TG. LRRTM4 is a member of the transsynaptic complex between rod photoreceptors and bipolar cells. The Journal of Comparative Neurology. PMID 32390181 DOI: 10.1002/Cne.24944  0.744
2020 Wensel TG. Phosphoinositides in Retinal Function and Disease. Cells. 9. PMID 32252387 DOI: 10.3390/Cells9040866  0.396
2019 Robichaux MA, Potter VL, Zhang Z, He F, Liu J, Schmid MF, Wensel TG. Defining the layers of a sensory cilium with STORM and cryoelectron nanoscopy. Proceedings of the National Academy of Sciences of the United States of America. PMID 31690665 DOI: 10.1073/Pnas.1902003116  0.772
2019 Terrón-Díaz ME, Wright SJ, Agosto MA, Lichtarge O, Wensel TG. Residues and residue pairs of evolutionary importance differentially direct signaling bias of D2 dopamine receptors. The Journal of Biological Chemistry. PMID 31676688 DOI: 10.1074/Jbc.Ra119.008068  0.726
2019 Tang J, Robichaux M, Wu KL, Pei J, Nguyen NT, Zhou Y, Wensel TG, Xiao H. Single-Atom Fluorescence Switch: A General Approach towards Visible Light-Activated Dyes for Biological Imaging. Journal of the American Chemical Society. PMID 31450884 DOI: 10.1021/Jacs.9B06237  0.745
2019 He F, Nichols RM, Kailasam L, Wensel TG, Agosto MA. Critical Role for Phosphatidylinositol-3 Kinase Vps34/PIK3C3 in ON-Bipolar Cells. Investigative Ophthalmology & Visual Science. 60: 2861-2874. PMID 31260037 DOI: 10.1167/Iovs.19-26586  0.718
2018 Dosey TL, Wang Z, Fan G, Zhang Z, Serysheva II, Chiu W, Wensel TG. Structures of TRPV2 in distinct conformations provide insight into role of the pore turret. Nature Structural & Molecular Biology. PMID 30598551 DOI: 10.1038/S41594-018-0168-8  0.321
2018 Agosto MA, Anastassov IA, Robichaux MA, Wensel TG. A Large Endoplasmic Reticulum-Resident Pool of TRPM1 in Retinal ON-Bipolar Cells. Eneuro. 5. PMID 30027108 DOI: 10.1523/ENEURO.0143-18.2018  0.791
2018 Dharmat R, Eblimit A, Robichaux MA, Zhang Z, Nguyen TT, Jung SY, He F, Jain A, Li Y, Qin J, Overbeek P, Roepman R, Mardon G, Wensel TG, Chen R. SPATA7 maintains a novel photoreceptor-specific zone in the distal connecting cilium. The Journal of Cell Biology. PMID 29899041 DOI: 10.1083/Jcb.201712117  0.789
2018 Yu B, Egbejimi A, Dharmat R, Xu P, Zhao Z, Long B, Miao H, Chen R, Wensel TG, Cai J, Chen Y. Phagocytosed photoreceptor outer segments activate mTORC1 in the retinal pigment epithelium. Science Signaling. 11. PMID 29844054 DOI: 10.1126/Scisignal.Aag3315  0.79
2018 Agosto MA, Anastassov IA, Wensel TG. Differential epitope masking reveals synapse-specific complexes of TRPM1. Visual Neuroscience. 35: E001. PMID 29370879 DOI: 10.1017/S0952523817000360  0.73
2017 Galaz-Montoya M, Wright SJ, Rodriguez GJ, Lichtarge O, Wensel TG. Beta-2 Adrenergic Receptor Activation Mobilizes Intracellular Calcium via a Non-Canonical cAMP-Independent Signaling Pathway. The Journal of Biological Chemistry. PMID 28442571 DOI: 10.1074/Jbc.M117.787119  0.315
2016 Wensel TG, Zhang Z, Anastassov IA, Gilliam JC, He F, Schmid MF, Robichaux MA. Structural and molecular bases of rod photoreceptor morphogenesis and disease. Progress in Retinal and Eye Research. PMID 27352937 DOI: 10.1016/J.Preteyeres.2016.06.002  0.759
2016 He F, Agosto MA, Anastassov IA, Tse DY, Wu SM, Wensel TG. Phosphatidylinositol-3-phosphate is light-regulated and essential for survival in retinal rods. Scientific Reports. 6: 26978. PMID 27245220 DOI: 10.1038/Srep26978  0.749
2016 Zhao L, Chen Y, Bajaj AO, Eblimit A, Xu M, Soens ZT, Wang F, Ge Z, Jung SY, He F, Li Y, Wensel TG, Qin J, Chen R. Integrative subcellular proteomic analysis allows accurate prediction of human disease causing genes. Genome Research. PMID 26912414 DOI: 10.1101/Gr.198911.115  0.371
2016 Zhang Z, He F, Schmid MF, Wensel TG. Three-Dimensional Structures Associated with Photoreceptor Cilia by Cryo-Electron Tomography Biophysical Journal. 110: 129a-130a. DOI: 10.1016/J.Bpj.2015.11.742  0.377
2016 Dosey TL, Wang Z, Guizhen F, Serysheva II, Chiu W, Wensel TG. Structural Basis of TRPV2 Channel Gating Investigated with cryo-EM Biophysical Journal. 110: 25a. DOI: 10.1016/J.Bpj.2015.11.201  0.325
2015 Roman-Sanchez R, Wensel TG, Wilson JH. Nonsense mutations in the rhodopsin gene that give rise to mild phenotypes trigger mRNA degradation in human cells by nonsense-mediated decay. Experimental Eye Research. PMID 26416182 DOI: 10.1016/J.Exer.2015.09.013  0.305
2015 Zhang Z, He F, Constantine R, Baker ML, Baehr W, Schmid MF, Wensel TG, Agosto MA. Domain organization and conformational plasticity of the G protein effector, PDE6. The Journal of Biological Chemistry. 290: 17131-2. PMID 26163476 DOI: 10.1074/Jbc.A115.647636  0.721
2015 Wang S, Tan KL, Agosto MA, Xiong B, Yamamoto S, Sandoval H, Jaiswal M, Bayat V, Zhang K, Charng WL, David G, Duraine L, Venkatachalam K, Wensel TG, Bellen HJ. Correction: the retromer complex is required for rhodopsin recycling and its loss leads to photoreceptor degeneration. Plos Biology. 13: e1002170. PMID 26020534 DOI: 10.1371/Journal.Pbio.1002170  0.698
2015 Zhang Z, He F, Constantine R, Baker ML, Baehr W, Schmid MF, Wensel TG, Agosto MA. Domain organization and conformational plasticity of the G protein effector, PDE6. The Journal of Biological Chemistry. 290: 12833-43. PMID 25809480 DOI: 10.1074/Jbc.M115.647636  0.736
2015 Wensel TG, Gilliam JC. Three-dimensional architecture of murine rod cilium revealed by cryo-EM. Methods in Molecular Biology (Clifton, N.J.). 1271: 267-92. PMID 25697530 DOI: 10.1007/978-1-4939-2330-4_18  0.39
2015 Kang HJ, Wilkins AD, Lichtarge O, Wensel TG. Determinants of endogenous ligand specificity divergence among metabotropic glutamate receptors. The Journal of Biological Chemistry. 290: 2870-8. PMID 25519912 DOI: 10.1074/Jbc.M114.622233  0.527
2014 Sandoval IM, Price BA, Gross AK, Chan F, Sammons JD, Wilson JH, Wensel TG. Abrupt onset of mutations in a developmentally regulated gene during terminal differentiation of post-mitotic photoreceptor neurons in mice. Plos One. 9: e108135. PMID 25264759 DOI: 10.1371/Journal.Pone.0108135  0.782
2014 Kang HJ, Menlove K, Ma J, Wilkins A, Lichtarge O, Wensel TG. Selectivity and evolutionary divergence of metabotropic glutamate receptors for endogenous ligands and G proteins coupled to phospholipase C or TRP channels. The Journal of Biological Chemistry. 289: 29961-74. PMID 25193666 DOI: 10.1074/Jbc.M114.574483  0.553
2014 Agosto MA, Zhang Z, He F, Anastassov IA, Wright SJ, McGehee J, Wensel TG. Oligomeric state of purified transient receptor potential melastatin-1 (TRPM1), a protein essential for dim light vision. The Journal of Biological Chemistry. 289: 27019-33. PMID 25112866 DOI: 10.1074/Jbc.M114.593780  0.756
2014 Wang S, Tan KL, Agosto MA, Xiong B, Yamamoto S, Sandoval H, Jaiswal M, Bayat V, Zhang K, Charng WL, David G, Duraine L, Venkatachalam K, Wensel TG, Bellen HJ. The retromer complex is required for rhodopsin recycling and its loss leads to photoreceptor degeneration. Plos Biology. 12: e1001847. PMID 24781186 DOI: 10.1371/Journal.Pbio.1001847  0.751
2013 Arshavsky VY, Wensel TG. Timing is everything: GTPase regulation in phototransduction. Investigative Ophthalmology & Visual Science. 54: 7725-33. PMID 24265205 DOI: 10.1167/Iovs.13-13281  0.43
2012 Price BA, Sandoval IM, Chan F, Nichols R, Roman-Sanchez R, Wensel TG, Wilson JH. Rhodopsin gene expression determines rod outer segment size and rod cell resistance to a dominant-negative neurodegeneration mutant. Plos One. 7: e49889. PMID 23185477 DOI: 10.1371/Journal.Pone.0049889  0.339
2012 Gilliam JC, Chang JT, Sandoval IM, Zhang Y, Li T, Pittler SJ, Chiu W, Wensel TG. Three-dimensional architecture of the rod sensory cilium and its disruption in retinal neurodegeneration. Cell. 151: 1029-41. PMID 23178122 DOI: 10.1016/J.Cell.2012.10.038  0.393
2011 Price BA, Sandoval IM, Chan F, Simons DL, Wu SM, Wensel TG, Wilson JH. Mislocalization and degradation of human P23H-rhodopsin-GFP in a knockin mouse model of retinitis pigmentosa. Investigative Ophthalmology & Visual Science. 52: 9728-36. PMID 22110080 DOI: 10.1167/Iovs.11-8654  0.339
2011 Gilliam JC, Wensel TG. TRP channel gene expression in the mouse retina. Vision Research. 51: 2440-52. PMID 22037305 DOI: 10.1016/J.Visres.2011.10.009  0.334
2011 Chan F, Hauswirth WW, Wensel TG, Wilson JH. Efficient mutagenesis of the rhodopsin gene in rod photoreceptor neurons in mice. Nucleic Acids Research. 39: 5955-66. PMID 21478169 DOI: 10.1093/Nar/Gkr196  0.356
2011 Moiseenkova-Bell V, Wensel TG. Functional and structural studies of TRP channels heterologously expressed in budding yeast. Advances in Experimental Medicine and Biology. 704: 25-40. PMID 21290288 DOI: 10.1007/978-94-007-0265-3_2  0.674
2011 Baehr W, Wensel T, Hageman G, Wu S, Zack D. Retinal ganglion cells: development, function, and disease. Vision Research. 51: 223. PMID 21251506 DOI: 10.1016/J.Visres.2011.01.005  0.306
2011 Gilliam JC, Chang JT, Chiu W, Wensel TG. Electron Cryo-Tomography of Cilia-Associated Structures of Rod Photoreceptors Biophysical Journal. 100: 338a. DOI: 10.1016/J.Bpj.2010.12.2049  0.396
2010 Rodriguez GJ, Yao R, Lichtarge O, Wensel TG. Evolution-guided discovery and recoding of allosteric pathway specificity determinants in psychoactive bioamine receptors. Proceedings of the National Academy of Sciences of the United States of America. 107: 7787-92. PMID 20385837 DOI: 10.1073/Pnas.0914877107  0.313
2010 Budzynski E, Gross AK, McAlear SD, Peachey NS, Shukla M, He F, Edwards M, Won J, Hicks WL, Wensel TG, Naggert JK, Nishina PM. Mutations of the opsin gene (Y102H and I307N) lead to light-induced degeneration of photoreceptors and constitutive activation of phototransduction in mice. The Journal of Biological Chemistry. 285: 14521-33. PMID 20207741 DOI: 10.1074/Jbc.M110.112409  0.698
2010 Jeffrey BG, Morgans CW, Puthussery T, Wensel TG, Burke NS, Brown RL, Duvoisin RM. R9AP stabilizes RGS11-G beta5 and accelerates the early light response of ON-bipolar cells. Visual Neuroscience. 27: 9-17. PMID 20100392 DOI: 10.1017/S0952523809990319  0.374
2010 Mancuso JJ, Qian Y, Long C, Wu GY, Wensel TG. Distribution of RGS9-2 in neurons of the mouse striatum. Journal of Neurochemistry. 112: 651-61. PMID 19912469 DOI: 10.1111/J.1471-4159.2009.06488.X  0.662
2009 Yao CK, Lin YQ, Ly CV, Ohyama T, Haueter CM, Moiseenkova-Bell VY, Wensel TG, Bellen HJ. A synaptic vesicle-associated Ca2+ channel promotes endocytosis and couples exocytosis to endocytosis. Cell. 138: 947-60. PMID 19737521 DOI: 10.1016/J.Cell.2009.06.033  0.654
2009 Mancuso JJ, Larson AM, Wensel TG, Saggau P. Multiphoton adaptation of a commercial low-cost confocal microscope for live tissue imaging. Journal of Biomedical Optics. 14: 034048. PMID 19566340 DOI: 10.1117/1.3139850  0.578
2009 Mojumder DK, Qian Y, Wensel TG. Two R7 regulator of G-protein signaling proteins shape retinal bipolar cell signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 7753-65. PMID 19535587 DOI: 10.1523/Jneurosci.1794-09.2009  0.357
2009 Moiseenkova-Bell VY, Wensel TG. Hot on the trail of TRP channel structure. The Journal of General Physiology. 133: 239-44. PMID 19237588 DOI: 10.1085/Jgp.200810123  0.665
2009 Sakamoto K, McCluskey M, Wensel TG, Naggert JK, Nishina PM. New mouse models for recessive retinitis pigmentosa caused by mutations in the Pde6a gene. Human Molecular Genetics. 18: 178-92. PMID 18849587 DOI: 10.1093/Hmg/Ddn327  0.414
2009 Moiseenkova-Bell V, Chen B, Tobe B, Serysheva I, Wensel T. Molecular Basis of Calmodulin and Ca2+ interaction with thermoTRP channels Biophysical Journal. 96: 267a. DOI: 10.1016/J.Bpj.2008.12.1318  0.677
2009 Wensel TG, He F, Wang Q, Zhang Z. Structure and Dynamics of Signal Transducing Membrane Complexes Biophysical Journal. 96: 198a-199a. DOI: 10.1016/J.Bpj.2008.12.1067  0.376
2008 Wang Q, Zhang X, Zhang L, He F, Zhang G, Jamrich M, Wensel TG. Activation-dependent hindrance of photoreceptor G protein diffusion by lipid microdomains. The Journal of Biological Chemistry. 283: 30015-24. PMID 18713731 DOI: 10.1074/Jbc.M803953200  0.373
2008 Moiseenkova-Bell VY, Stanciu LA, Serysheva II, Tobe BJ, Wensel TG. Structure of TRPV1 channel revealed by electron cryomicroscopy. Proceedings of the National Academy of Sciences of the United States of America. 105: 7451-5. PMID 18490661 DOI: 10.1073/Pnas.0711835105  0.678
2008 Benfield AP, Macleod MC, Liu Y, Wu Q, Wensel TG, Vasquez KM. Targeted generation of DNA strand breaks using pyrene-conjugated triplex-forming oligonucleotides. Biochemistry. 47: 6279-88. PMID 18473480 DOI: 10.1021/Bi7024029  0.575
2008 Wensel TG. Signal transducing membrane complexes of photoreceptor outer segments. Vision Research. 48: 2052-61. PMID 18456304 DOI: 10.1016/J.Visres.2008.03.010  0.393
2007 Morgans CW, Wensel TG, Brown RL, Perez-Leon JA, Bearnot B, Duvoisin RM. Gbeta5-RGS complexes co-localize with mGluR6 in retinal ON-bipolar cells. The European Journal of Neuroscience. 26: 2899-905. PMID 18001285 DOI: 10.1111/J.1460-9568.2007.05867.X  0.419
2007 Marc RE, Jones BW, Anderson JR, Kinard K, Marshak DW, Wilson JH, Wensel T, Lucas RJ. Neural reprogramming in retinal degeneration. Investigative Ophthalmology & Visual Science. 48: 3364-71. PMID 17591910 DOI: 10.1167/Iovs.07-0032  0.354
2007 Song JH, Song H, Wensel TG, Sokolov M, Martemyanov KA. Localization and differential interaction of R7 RGS proteins with their membrane anchors R7BP and R9AP in neurons of vertebrate retina. Molecular and Cellular Neurosciences. 35: 311-9. PMID 17442586 DOI: 10.1016/J.Mcn.2007.03.006  0.374
2006 Gross AK, Decker G, Chan F, Sandoval IM, Wilson JH, Wensel TG. Defective development of photoreceptor membranes in a mouse model of recessive retinal degeneration. Vision Research. 46: 4510-8. PMID 16979686 DOI: 10.1016/J.Visres.2006.07.012  0.716
2006 Krispel CM, Chen D, Melling N, Chen YJ, Martemyanov KA, Quillinan N, Arshavsky VY, Wensel TG, Chen CK, Burns ME. RGS expression rate-limits recovery of rod photoresponses. Neuron. 51: 409-16. PMID 16908407 DOI: 10.1016/J.Neuron.2006.07.010  0.375
2006 Zhang X, Wensel TG, Yuan C. Tokay gecko photoreceptors achieve rod-like physiology with cone-like proteins. Photochemistry and Photobiology. 82: 1452-60. PMID 16553462 DOI: 10.1562/2006-01-05-Ra-767  0.418
2005 Wensel TG, Gross AK, Chan F, Sykoudis K, Wilson JH. Rhodopsin-EGFP knock-ins for imaging quantal gene alterations. Vision Research. 45: 3445-53. PMID 16139321 DOI: 10.1016/J.Visres.2005.07.016  0.689
2005 Wiszniewski W, Zaremba CM, Yatsenko AN, Jamrich M, Wensel TG, Lewis RA, Lupski JR. ABCA4 mutations causing mislocalization are found frequently in patients with severe retinal dystrophies. Human Molecular Genetics. 14: 2769-78. PMID 16103129 DOI: 10.1093/HMG/DDI310  0.363
2005 Wensel TG, He F, Malinski JA. Purification, reconstitution on lipid vesicles, and assays of PDE6 and its activator G protein, transducin. Methods in Molecular Biology (Clifton, N.J.). 307: 289-313. PMID 15988071 DOI: 10.1385/1-59259-839-0:289  0.4
2004 Hu G, Wensel TG. Characterization of R9AP, a membrane anchor for the photoreceptor GTPase-accelerating protein, RGS9-1. Methods in Enzymology. 390: 178-96. PMID 15488178 DOI: 10.1016/S0076-6879(04)90012-2  0.623
2004 Chan F, Bradley A, Wensel TG, Wilson JH. Knock-in human rhodopsin-GFP fusions as mouse models for human disease and targets for gene therapy. Proceedings of the National Academy of Sciences of the United States of America. 101: 9109-14. PMID 15184660 DOI: 10.1073/Pnas.0403149101  0.371
2004 Zhang Z, Melia TJ, He F, Yuan C, McGough A, Schmid MF, Wensel TG. How a G protein binds a membrane. The Journal of Biological Chemistry. 279: 33937-45. PMID 15173184 DOI: 10.1074/Jbc.M403404200  0.684
2004 He F, Mao M, Wensel TG. Enhancement of phototransduction g protein-effector interactions by phosphoinositides. The Journal of Biological Chemistry. 279: 8986-90. PMID 14699118 DOI: 10.1074/Jbc.M311488200  0.372
2004 Madabushi S, Gross AK, Philippi A, Meng EC, Wensel TG, Lichtarge O. Evolutionary trace of G protein-coupled receptors reveals clusters of residues that determine global and class-specific functions. The Journal of Biological Chemistry. 279: 8126-32. PMID 14660595 DOI: 10.1074/Jbc.M312671200  0.719
2003 Zhang L, El-Hodiri HM, Ma HF, Zhang X, Servetnick M, Wensel TG, Jamrich M. Targeted expression of the dominant-negative FGFR4a in the eye using Xrx1A regulatory sequences interferes with normal retinal development. Development (Cambridge, England). 130: 4177-86. PMID 12874136 DOI: 10.1242/Dev.00626  0.346
2003 Chen CK, Eversole-Cire P, Zhang H, Mancino V, Chen YJ, He W, Wensel TG, Simon MI. Instability of GGL domain-containing RGS proteins in mice lacking the G protein beta-subunit Gbeta5. Proceedings of the National Academy of Sciences of the United States of America. 100: 6604-9. PMID 12738888 DOI: 10.1073/Pnas.0631825100  0.384
2003 Kennedy MJ, Sowa ME, Wensel TG, Hurley JB. Acceleration of key reactions as a strategy to elucidate the rate-limiting chemistry underlying phototransduction inactivation. Investigative Ophthalmology & Visual Science. 44: 1016-22. PMID 12601023 DOI: 10.1167/Iovs.02-0692  0.5
2003 Zhang X, Wensel TG, Kraft TW. GTPase regulators and photoresponses in cones of the eastern chipmunk. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 1287-97. PMID 12598617 DOI: 10.1523/Jneurosci.23-04-01287.2003  0.421
2003 Hu G, Zhang Z, Wensel TG. Activation of RGS9-1GTPase acceleration by its membrane anchor, R9AP. The Journal of Biological Chemistry. 278: 14550-4. PMID 12560335 DOI: 10.1074/Jbc.M212046200  0.587
2003 Sokal I, Hu G, Liang Y, Mao M, Wensel TG, Palczewski K. Identification of protein kinase C isozymes responsible for the phosphorylation of photoreceptor-specific RGS9-1 at Ser475. The Journal of Biological Chemistry. 278: 8316-25. PMID 12499365 DOI: 10.1074/Jbc.M211782200  0.581
2002 Wensel TG. RGS9-1 phosphorylation and Ca2+. Advances in Experimental Medicine and Biology. 514: 125-9. PMID 12596919 DOI: 10.1007/978-1-4615-0121-3_8  0.314
2002 Hu G, Wensel TG. R9AP, a membrane anchor for the photoreceptor GTPase accelerating protein, RGS9-1. Proceedings of the National Academy of Sciences of the United States of America. 99: 9755-60. PMID 12119397 DOI: 10.1073/Pnas.152094799  0.601
2002 Imanishi Y, Li N, Sokal I, Sowa ME, Lichtarge O, Wensel TG, Saperstein DA, Baehr W, Palczewski K. Characterization of retinal guanylate cyclase-activating protein 3 (GCAP3) from zebrafish to man. The European Journal of Neuroscience. 15: 63-78. PMID 11860507 DOI: 10.1046/J.0953-816X.2001.01835.X  0.399
2002 Sierra DA, Gilbert DJ, Householder D, Grishin NV, Yu K, Ukidwe P, Barker SA, He W, Wensel TG, Otero G, Brown G, Copeland NG, Jenkins NA, Wilkie TM. Evolution of the regulators of G-protein signaling multigene family in mouse and human. Genomics. 79: 177-85. PMID 11829488 DOI: 10.1006/Geno.2002.6693  0.353
2001 Shroyer NF, Lewis RA, Yatsenko AN, Wensel TG, Lupski JR. Cosegregation and functional analysis of mutant ABCR (ABCA4) alleles in families that manifest both Stargardt disease and age-related macular degeneration. Human Molecular Genetics. 10: 2671-8. PMID 11726554 DOI: 10.1093/Hmg/10.23.2671  0.321
2001 He W, Melia TJ, Cowan CW, Wensel TG. Dependence of RGS9-1 membrane attachment on its C-terminal tail. The Journal of Biological Chemistry. 276: 48961-6. PMID 11677233 DOI: 10.1074/Jbc.M107428200  0.775
2001 Hu G, Jang GF, Cowan CW, Wensel TG, Palczewski K. Phosphorylation of RGS9-1 by an endogenous protein kinase in rod outer segments. The Journal of Biological Chemistry. 276: 22287-95. PMID 11292825 DOI: 10.1074/Jbc.M011539200  0.714
2001 Slep KC, Kercher MA, He W, Cowan CW, Wensel TG, Sigler PB. Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A. Nature. 409: 1071-7. PMID 11234020 DOI: 10.1038/35059138  0.669
2001 Sowa ME, He W, Slep KC, Kercher MA, Lichtarge O, Wensel TG. Prediction and confirmation of a site critical for effector regulation of RGS domain activity. Nature Structural Biology. 8: 234-7. PMID 11224568 DOI: 10.1038/84974  0.369
2001 Cowan CW, He W, Wensel TG. RGS proteins: lessons from the RGS9 subfamily. Progress in Nucleic Acid Research and Molecular Biology. 65: 341-59. PMID 11008492 DOI: 10.1016/S0079-6603(00)65009-2  0.688
2000 Intody Z, Perkins BD, Wilson JH, Wensel TG. Blocking transcription of the human rhodopsin gene by triplex-mediated DNA photocrosslinking. Nucleic Acids Research. 28: 4283-90. PMID 11058128 DOI: 10.1093/Nar/28.21.4283  0.668
2000 He F, Seryshev AB, Cowan CW, Wensel TG. Multiple zinc binding sites in retinal rod cGMP phosphodiesterase, PDE6alpha beta. The Journal of Biological Chemistry. 275: 20572-7. PMID 10787404 DOI: 10.1074/Jbc.M000440200  0.627
2000 Womack KB, Gordon SE, He F, Wensel TG, Lu CC, Hilgemann DW. Do phosphatidylinositides modulate vertebrate phototransduction? The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 2792-9. PMID 10751430 DOI: 10.1523/Jneurosci.20-08-02792.2000  0.344
2000 Cowan CW, Wensel TG, Arshavsky VY. Enzymology of GTPase acceleration in phototransduction. Methods in Enzymology. 315: 524-38. PMID 10736724 DOI: 10.1016/S0076-6879(00)15865-3  0.603
2000 Sowa ME, He W, Wensel TG, Lichtarge O. A regulator of G protein signaling interaction surface linked to effector specificity. Proceedings of the National Academy of Sciences of the United States of America. 97: 1483-8. PMID 10677488 DOI: 10.1073/Pnas.030409597  0.322
2000 Melia TJ, Malinski JA, He F, Wensel TG. Enhancement of phototransduction protein interactions by lipid surfaces. The Journal of Biological Chemistry. 275: 3535-42. PMID 10652348 DOI: 10.1074/Jbc.275.5.3535  0.671
1999 Melia TJ, Sowa ME, Schutze L, Wensel TG. Formation of helical protein assemblies of IgG and transducin on varied lipid tubules. Journal of Structural Biology. 128: 119-30. PMID 10600566 DOI: 10.1006/Jsbi.1999.4151  0.674
1999 Zhang K, Howes KA, He W, Bronson JD, Pettenati MJ, Chen C, Palczewski K, Wensel TG, Baehr W. Structure, alternative splicing, and expression of the human RGS9 gene. Gene. 240: 23-34. PMID 10564809 DOI: 10.1016/S0378-1119(99)00393-5  0.357
1999 Perkins BD, Wensel TG, Vasquez KM, Wilson JH. Psoralen photo-cross-linking by triplex-forming oligonucleotides at multiple sites in the human rhodopsin gene. Biochemistry. 38: 12850-9. PMID 10504255 DOI: 10.1021/Bi9902743  0.748
1999 DeMar JC, Rundle DR, Wensel TG, Anderson RE. Heterogeneous N-terminal acylation of retinal proteins. Progress in Lipid Research. 38: 49-90. PMID 10396602 DOI: 10.1016/S0163-7827(98)00020-4  0.347
1999 Rahman Z, Gold SJ, Potenza MN, Cowan CW, Ni YG, He W, Wensel TG, Nestler EJ. Cloning and characterization of RGS9-2: a striatal-enriched alternatively spliced product of the RGS9 gene. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 2016-26. PMID 10066255 DOI: 10.1523/Jneurosci.19-06-02016.1999  0.692
1998 Perkins BD, Wilson JH, Wensel TG, Vasquez KM. Triplex targets in the human rhodopsin gene. Biochemistry. 37: 11315-22. PMID 9698379 DOI: 10.1021/Bi980525S  0.747
1998 Cowan CW, Fariss RN, Sokal I, Palczewski K, Wensel TG. High expression levels in cones of RGS9, the predominant GTPase accelerating protein of rods. Proceedings of the National Academy of Sciences of the United States of America. 95: 5351-6. PMID 9560279 DOI: 10.1073/Pnas.95.9.5351  0.691
1998 He W, Cowan CW, Wensel TG. RGS9, a GTPase accelerator for phototransduction. Neuron. 20: 95-102. PMID 9459445 DOI: 10.1016/S0896-6273(00)80437-7  0.682
1997 Melia TJ, Cowan CW, Angleson JK, Wensel TG. A comparison of the efficiency of G protein activation by ligand-free and light-activated forms of rhodopsin. Biophysical Journal. 73: 3182-91. PMID 9414230 DOI: 10.1016/S0006-3495(97)78344-9  0.796
1996 Vasquez KM, Wensel TG, Hogan ME, Wilson JH. High-efficiency triple-helix-mediated photo-cross-linking at a targeted site within a selectable mammalian gene. Biochemistry. 35: 10712-9. PMID 8718860 DOI: 10.1021/Bi960881F  0.592
1996 Zera EM, Molloy DP, Angleson JK, Lamture JB, Wensel TG, Malinski JA. Low affinity interactions of GDPbetaS and ribose- or phosphoryl-substituted GTP analogues with the heterotrimeric G protein, transducin. The Journal of Biological Chemistry. 271: 12925-31. PMID 8662741 DOI: 10.1074/Jbc.271.22.12925  0.718
1996 Malinski JA, Zera EM, Angleson JK, Wensel TG. High affinity interactions of GTPgammaS with the heterotrimeric G protein, transducin. Evidence at high and low protein concentrations. The Journal of Biological Chemistry. 271: 12919-24. PMID 8662740 DOI: 10.1074/Jbc.271.22.12919  0.715
1996 Cowan CW, Angleson JK, Wensel TG. Solubilization and partial purification of Gtα-GAP from rod outer segment membranes Investigative Ophthalmology and Visual Science. 37: S809.  0.773
1996 Melia TJ, Malinski JA, McGough A, Wensel TG. Ordered two-dimensional and helical arrays of transducin bound to lipid surfaces Investigative Ophthalmology and Visual Science. 37: S238.  0.575
1996 Wensel TG, Seryshev A, Cowan CW. Zinc and retinal cGMP phosphodiesterase Investigative Ophthalmology and Visual Science. 37: S239.  0.612
1996 Malinski JA, Melia TJ, Wensel TG. Stoichiometric activaton of retinal rod cGMP phosphodiesterase by Gtα-GTPγS Investigative Ophthalmology and Visual Science. 37: S809.  0.633
1995 Vasquez KM, Wensel TG, Hogan ME, Wilson JH. High-affinity triple helix formation by synthetic oligonucleotides at a site within a selectable mammalian gene. Biochemistry. 34: 7243-51. PMID 7766635 DOI: 10.1021/Bi00021A040  0.591
1995 Lamture JB, Wensel TG. Intensely luminescent immunoreactive conjugates of proteins and dipicolinate-based polymeric Tb (III) chelates. Bioconjugate Chemistry. 6: 88-92. PMID 7711110 DOI: 10.1021/Bc00031A010  0.318
1994 Angleson JK, Wensel TG. Enhancement of rod outer segment GTPase accelerating protein activity by the inhibitory subunit of cGMP phosphodiesterase. The Journal of Biological Chemistry. 269: 16290-6. PMID 8206935  0.701
1993 Angleson JK, Wensel TG. A GTPase-accelerating factor for transducin, distinct from its effector cGMP phosphodiesterase, in rod outer segment membranes. Neuron. 11: 939-49. PMID 8240815 DOI: 10.1016/0896-6273(93)90123-9  0.741
1992 Malinski JA, Wensel TG. Membrane stimulation of cGMP phosphodiesterase activation by transducin: comparison of phospholipid bilayers to rod outer segment membranes. Biochemistry. 31: 9502-12. PMID 1327116 DOI: 10.1021/Bi00154A024  0.336
1991 Ramdas L, Disher RM, Wensel TG. Nucleotide exchange and cGMP phosphodiesterase activation by pertussis toxin inactivated transducin. Biochemistry. 30: 11637-45. PMID 1661143 DOI: 10.1021/Bi00114A005  0.361
1991 Wensel TG. G Proteins.Ravi Iyengar , Lutz Birnbaumer The Quarterly Review of Biology. 66: 333-333. DOI: 10.1086/417263  0.31
1990 Northrup SH, Wensel TG, Meares CF, Wendoloski JJ, Matthew JB. Electrostatic field around cytochrome c: theory and energy transfer experiment. Proceedings of the National Academy of Sciences of the United States of America. 87: 9503-7. PMID 2174564 DOI: 10.1073/Pnas.87.23.9503  0.536
1990 Wensel TG, Stryer L. Activation mechanism of retinal rod cyclic GMP phosphodiesterase probed by fluorescein-labeled inhibitory subunit. Biochemistry. 29: 2155-61. PMID 2158346 DOI: 10.1021/Bi00460A028  0.583
1990 Holowka D, Wensel T, Baird B. A nanosecond fluorescence depolarization study on the segmental flexibility of receptor-bound immunoglobulin E. Biochemistry. 29: 4607-12. PMID 2142605 DOI: 10.1021/Bi00471A015  0.313
1990 Meyer T, Wensel T, Stryer L. Kinetics of calcium channel opening by inositol 1,4,5-trisphosphate. Biochemistry. 29: 32-7. PMID 1691015 DOI: 10.1021/Bi00453A004  0.554
1989 Wensel TG, Meares CF. Study of biological macromolecules by diffusion-enhanced lanthanide energy transfer Journal of the Less-Common Metals. 149: 143-160. DOI: 10.1016/0022-5088(89)90481-5  0.503
1988 Dangl JL, Wensel TG, Morrison SL, Stryer L, Herzenberg LA, Oi VT. Segmental flexibility and complement fixation of genetically engineered chimeric human, rabbit and mouse antibodies. The Embo Journal. 7: 1989-94. PMID 3138110 DOI: 10.1002/J.1460-2075.1988.Tb03037.X  0.554
1988 Schneider WP, Wensel TG, Stryer L, Oi VT. Genetically engineered immunoglobulins reveal structural features controlling segmental flexibility. Proceedings of the National Academy of Sciences of the United States of America. 85: 2509-13. PMID 3128789 DOI: 10.1073/Pnas.85.8.2509  0.567
1988 Dangl JL, Wensel TG, Morrison SL, Stryer L, Herzenberg LA, Oi VT. Segmental flexibility and complement fixation of genetically engineered chimeric human, rabbit and mouse antibodies. The Embo Journal. 7: 1989-1994. DOI: 10.1002/j.1460-2075.1988.tb03037.x  0.498
1986 Wensel TG, Meares CF, Vlachy V, Matthew JB. Distribution of ions around DNA, probed by energy transfer. Proceedings of the National Academy of Sciences of the United States of America. 83: 3267-71. PMID 3458180 DOI: 10.1073/Pnas.83.10.3267  0.483
1986 Haseman MK, Goodwin DA, Meares CF, Kaminski MS, Wensel TG, McCall MJ, Levy R. Metabolizable 111In chelate conjugated anti-idiotype monoclonal antibody for radioimmunodetection of lymphoma in mice. European Journal of Nuclear Medicine. 12: 455-60. PMID 3102237 DOI: 10.1007/Bf00254750  0.5
1986 Wensel TG, Stryer L. Reciprocal control of retinal rod cyclic GMP phosphodiesterase by its gamma subunit and transducin. Proteins. 1: 90-9. PMID 2835761 DOI: 10.1002/Prot.340010114  0.57
1985 Wensel TG, Chang CH, Meares CF. Diffusion-enhanced lanthanide energy-transfer study of DNA-bound cobalt(III) bleomycins: comparisons of accessibility and electrostatic potential with DNA complexes of ethidium and acridine orange. Biochemistry. 24: 3060-9. PMID 2410019 DOI: 10.1021/Bi00333A039  0.501
1984 Haseman MK, Goodwin DA, Meares CF, Kaminski MS, Wensel T, McCall MJ, Levy R. Metabolizable In-111 Chelate Conjugated Anti-Idiotype Monoclonal Antibody For Radioimmunodetection Of Lymphoma In Mice Clinical Nuclear Medicine. 9: 39. DOI: 10.1097/00003072-198409001-00037  0.473
1984 Wensel T, Meares C. Corrections - Electrostatic Properties of Myoglobin Probed by Diffusion-Enhanced Energy Transfer Biochemistry. 23: 2540-2540. DOI: 10.1021/Bi00306A605  0.478
1984 Meares CF, Wensel TG. Metal chelates as probes of biological systems Accounts of Chemical Research. 17: 202-209. DOI: 10.1021/Ar00102A001  0.47
1983 Wensel TG, Meares CF. Electrostatic properties of myoglobin probed by diffusion-enhanced energy transfer Biochemistry. 22: 6247-6254. DOI: 10.1021/Bi00295A032  0.475
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