Karen H. Ashe - Publications

Affiliations: 
Neuroscience University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Neuroscience Biology, Medicine and Surgery

76 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Liu P, Lapcinski IP, Hlynialuk CJW, Steuer EL, Loude TJ, Shapiro SL, Kemper LJ, Ashe KH. Aβ∗56 is a stable oligomer that impairs memory function in mice. Iscience. 27: 109239. PMID 38433923 DOI: 10.1016/j.isci.2024.109239  0.404
2023 Liu P, Lapcinski IP, Shapiro SL, Kemper LJ, Ashe KH. Aβ*56 is a stable oligomer that correlates with age-related memory loss in Tg2576 mice. Biorxiv : the Preprint Server For Biology. PMID 36993768 DOI: 10.1101/2023.03.20.533414  0.456
2022 Pockes S, Walters MA, Ashe KH. Targeting caspase-2 interactions with tau in Alzheimer's disease and related dementias. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 36343883 DOI: 10.1016/j.trsl.2022.10.009  0.343
2022 Steuer EL, Kemper LJ, Hlynialuk CJW, Leinonen-Wright K, Montonye ML, Lapcinski IP, Forster CL, Ashe KH, Liu P. Blocking site-specific cleavage of human tau delays progression of disease-related phenotypes in genetically matched tau-transgenic mice modeling frontotemporal dementia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 35508385 DOI: 10.1523/JNEUROSCI.0543-22.2022  0.31
2021 Lyons CE, Zhou X, Razzoli M, Chen M, Xia W, Ashe K, Zhang B, Bartolomucci A. Lifelong chronic psychosocial stress induces a proteomic signature of Alzheimer's Disease in wildtype mice. The European Journal of Neuroscience. PMID 34048087 DOI: 10.1111/ejn.15329  0.334
2020 Ashe KH. The biogenesis and biology of amyloid β oligomers in the brain. Alzheimers & Dementia. 16: 1561-1567. PMID 32543725 DOI: 10.1002/Alz.12084  0.464
2019 Lo CH, Lim CK, Ding Z, Wickramasinghe SP, Braun AR, Ashe KH, Rhoades E, Thomas DD, Sachs JN. Targeting the ensemble of heterogeneous tau oligomers in cells: A novel small molecule screening platform for tauopathies. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31653529 DOI: 10.1016/J.Jalz.2019.06.4954  0.31
2019 Smith BR, Nelson KM, Kemper LJ, Leinonen-Wright K, Petersen A, Keene CD, Ashe KH. A soluble tau fragment generated by caspase-2 is associated with dementia in Lewy body disease. Acta Neuropathologica Communications. 7: 124. PMID 31362787 DOI: 10.1186/S40478-019-0765-8  0.342
2019 Grant MKO, Handoko M, Rozga M, Brinkmalm G, Portelius E, Blennow K, Ashe KH, Zahs KR, Liu P. Human cerebrospinal fluid 6E10-immunoreactive protein species contain amyloid precursor protein fragments. Plos One. 14: e0212815. PMID 30817799 DOI: 10.1371/Journal.Pone.0212815  0.685
2017 Liu P, Reichl JH, Rao ER, McNellis BM, Huang ES, Hemmy LS, Forster CL, Kuskowski MA, Borchelt DR, Vassar R, Ashe KH, Zahs KR. Quantitative Comparison of Dense-Core Amyloid Plaque Accumulation in Amyloid-β Protein Precursor Transgenic Mice. Journal of Alzheimer's Disease : Jad. PMID 28059792 DOI: 10.3233/Jad-161027  0.394
2016 Zhao X, Kotilinek LA, Smith B, Hlynialuk C, Zahs K, Ramsden M, Cleary J, Ashe KH. Caspase-2 cleavage of tau reversibly impairs memory. Nature Medicine. PMID 27723722 DOI: 10.1038/Nm.4199  0.383
2016 Lesne S, Amar F, Sherman M, Rush T, Larson M, Chang L, Götz J, Schneider J, Bennett D, Ashe K, Buisson A. Specific alterations of tau phosphorylation and neuronal signaling induced by the amyloid-β oligomer Aβ*56 Neurobiology of Aging. 39: S27. DOI: 10.1016/J.Neurobiolaging.2016.01.117  0.479
2016 Ashe K, Liu P, Reed M, Grant M, Forster C, Qiang W, Shapiro S, Jankowsky J, Wilmot C, Cleary J, Zahs K. Type 1 and Type 2 Aβ oligomers in the brain Neurobiology of Aging. 39: S26. DOI: 10.1016/J.Neurobiolaging.2016.01.116  0.35
2015 Liu P, Reed MN, Kotilinek LA, Grant MK, Forster CL, Qiang W, Shapiro SL, Reichl JH, Chiang AC, Jankowsky JL, Wilmot CM, Cleary JP, Zahs KR, Ashe KH. Quaternary Structure Defines a Large Class of Amyloid-β Oligomers Neutralized by Sequestration. Cell Reports. 11: 1760-71. PMID 26051935 DOI: 10.1016/J.Celrep.2015.05.021  0.5
2015 Liu P, Paulson JB, Forster CL, Shapiro SL, Ashe KH, Zahs KR. Characterization of a Novel Mouse Model of Alzheimer's Disease--Amyloid Pathology and Unique β-Amyloid Oligomer Profile. Plos One. 10: e0126317. PMID 25946042 DOI: 10.1371/journal.pone.0126317  0.467
2015 Zahs KR, Ashe KH. More than a FAD: the in vivo effects of disease-linked presenilin-1 mutations. Neuron. 85: 893-5. PMID 25741717 DOI: 10.1016/J.Neuron.2015.02.021  0.306
2014 Ashe K, Liu P, Reed M, Kotilinek L, Grant M, Forster C, Qiang W, Reich J, Cleary J, Zahs K. The relevance of Quaternary structure to the functional effects of amyloid-β oligomers in the brain Neurobiology of Aging. 35: S2. DOI: 10.1016/J.Neurobiolaging.2014.01.034  0.4
2013 Zahs KR, Ashe KH. β-Amyloid oligomers in aging and Alzheimer's disease. Frontiers in Aging Neuroscience. 5: 28. PMID 23847532 DOI: 10.3389/fnagi.2013.00028  0.4
2013 Lesné SE, Sherman MA, Grant M, Kuskowski M, Schneider JA, Bennett DA, Ashe KH. Brain amyloid-β oligomers in ageing and Alzheimer's disease. Brain : a Journal of Neurology. 136: 1383-98. PMID 23576130 DOI: 10.1093/Brain/Awt062  0.475
2013 Handoko M, Grant M, Kuskowski M, Zahs KR, Wallin A, Blennow K, Ashe KH. Correlation of specific amyloid-β oligomers with tau in cerebrospinal fluid from cognitively normal older adults. Jama Neurology. 70: 594-9. PMID 23479202 DOI: 10.1001/Jamaneurol.2013.48  0.698
2013 Ashe KH, Aguzzi A. Prions, prionoids and pathogenic proteins in Alzheimer disease. Prion. 7: 55-9. PMID 23208281 DOI: 10.4161/Pri.23061  0.374
2012 Orr ME, Pitstick R, Canine B, Ashe KH, Carlson GA. Genotype-specific differences between mouse CNS stem cell lines expressing frontotemporal dementia mutant or wild type human tau. Plos One. 7: e39328. PMID 22723997 DOI: 10.1371/Journal.Pone.0039328  0.304
2012 de Calignon A, Polydoro M, Suárez-Calvet M, William C, Adamowicz DH, Kopeikina KJ, Pitstick R, Sahara N, Ashe KH, Carlson GA, Spires-Jones TL, Hyman BT. Propagation of tau pathology in a model of early Alzheimer's disease. Neuron. 73: 685-97. PMID 22365544 DOI: 10.1016/J.Neuron.2011.11.033  0.315
2012 de Calignon A, Polydoro M, Suárez-Calvet M, William C, Adamowicz DH, Kopeikina KJ, Pitstick R, Sahara N, Ashe KH, Carlson GA, Spires-Jones TL, Hyman BT. Propagation of Tau Pathology in a Model of Early Alzheimer's Disease Neuron. 76: 461. DOI: 10.1016/j.neuron.2012.10.005  0.359
2012 Handoko M, Grant M, Kuskowski M, Wallin A, Blennow K, Ashe K. 3 Evidence in humans linking a specific amyloid-β oligomer to tau pathobiology Neurobiology of Aging. 33. DOI: 10.1016/J.Neurobiolaging.2012.01.021  0.673
2011 Breitner JC, Baker LD, Montine TJ, Meinert CL, Lyketsos CG, Ashe KH, Brandt J, Craft S, Evans DE, Green RC, Ismail MS, Martin BK, Mullan MJ, Sabbagh M, Tariot PN, et al. Extended results of the Alzheimer's disease anti-inflammatory prevention trial. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 7: 402-11. PMID 21784351 DOI: 10.1016/J.Jalz.2010.12.014  0.34
2011 Liu P, Kemper LJ, Wang J, Zahs KR, Ashe KH, Pasinetti GM. Grape seed polyphenolic extract specifically decreases aβ*56 in the brains of Tg2576 mice. Journal of Alzheimer's Disease : Jad. 26: 657-66. PMID 21743132 DOI: 10.3233/Jad-2011-110383  0.378
2011 Liu P, Forster C, Kotilinek L, Paulson J, Chen G, Bennett D, Cleary J, Zahs K, Lesne S, Ashe K. Abeta dimers mediate plaque-associated cytopathology without affecting cognition Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.09.067  0.363
2011 Handoko M, Wallin A, Blennow K, Ashe K. Specific Aβ oligomers and the tau/Aβ42 ratio correlate in lumbar puncture CSF Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.09.015  0.692
2010 Zahs KR, Ashe KH. 'Too much good news' - are Alzheimer mouse models trying to tell us how to prevent, not cure, Alzheimer's disease? Trends in Neurosciences. 33: 381-9. PMID 20542579 DOI: 10.1016/j.tins.2010.05.004  0.353
2010 Lesne SE, Sherman MA, Kuskowski MA, Schneider JA, Bennett DA, Ashe KH. P4-104: Evolution of Brain Aβ Oligomers Interactomes during the Course of Alzheimer's Disease Alzheimer's & Dementia. 6: e52-e52. DOI: 10.1016/J.Jalz.2010.08.162  0.478
2010 Hoover BR, Su J, Reed MN, Penrod RD, Lanier LM, Yuan L, Ashe KH, Liao D. P1-354: The mislocalization of tau to dendritic spines mediates synaptic dysfunction independent of neurodegeneration Alzheimer's & Dementia. 6: S275-S276. DOI: 10.1016/J.Jalz.2010.05.908  0.33
2010 Zhao X, Reed MN, Cleary JP, Ashe KH. P1-341: Transmission of tau-induced cognitive dysfunction Alzheimer's & Dementia. 6: S272-S272. DOI: 10.1016/J.Jalz.2010.05.894  0.337
2010 Handoko M, Wang P, Sreevatsan S, Ashe KH. P1-223: DNA aptamers against specific oligomeric Aβ species Alzheimer's & Dementia. 6: S238-S239. DOI: 10.1016/J.Jalz.2010.05.774  0.635
2010 Ashe KH. Alzheimer's Disease: Transgenic Mouse Models Encyclopedia of Neuroscience. 283-287. DOI: 10.1016/B978-008045046-9.00546-5  0.4
2010 Ashe KH. Animal Models to Study the Biology of Amyloid-β Protein Misfolding in Alzheimer Disease Protein Misfolding Diseases: Current and Emerging Principles and Therapies. 213-229. DOI: 10.1002/9780470572702.ch11  0.394
2008 Paulson JB, Ramsden M, Forster C, Sherman MA, McGowan E, Ashe KH. Amyloid plaque and neurofibrillary tangle pathology in a regulatable mouse model of Alzheimer's disease. The American Journal of Pathology. 173: 762-72. PMID 18669616 DOI: 10.2353/Ajpath.2008.080175  0.455
2008 Poling A, Morgan-Paisley K, Panos JJ, Kim EM, O'Hare E, Cleary JP, Lesné S, Ashe KH, Porritt M, Baker LE. Oligomers of the amyloid-beta protein disrupt working memory: confirmation with two behavioral procedures. Behavioural Brain Research. 193: 230-4. PMID 18585407 DOI: 10.1016/J.Bbr.2008.06.001  0.407
2008 Ning A, Cui J, To E, Ashe KH, Matsubara J. Amyloid-beta deposits lead to retinal degeneration in a mouse model of Alzheimer disease. Investigative Ophthalmology & Visual Science. 49: 5136-43. PMID 18566467 DOI: 10.1167/Iovs.08-1849  0.388
2008 Kotilinek LA, Westerman MA, Wang Q, Panizzon K, Lim GP, Simonyi A, Lesne S, Falinska A, Younkin LH, Younkin SG, Rowan M, Cleary J, Wallis RA, Sun GY, Cole G, ... ... Ashe KH, et al. Cyclooxygenase-2 inhibition improves amyloid-beta-mediated suppression of memory and synaptic plasticity. Brain : a Journal of Neurology. 131: 651-64. PMID 18292081 DOI: 10.1093/Brain/Awn008  0.327
2008 Lesné S, Kotilinek L, Ashe KH. Plaque-bearing mice with reduced levels of oligomeric amyloid-β assemblies have intact memory function Neuroscience. 151: 745-749. PMID 18155846 DOI: 10.1016/J.Neuroscience.2007.10.054  0.428
2008 Orr ME, Giri RK, Ashe KH, Carlson GA. P1-095: CNS stem cell lines from tau transgenic mice as models for frontotemporal dementia Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.681  0.364
2007 Ashe KH. A tale about tau. The New England Journal of Medicine. 357: 933-5. PMID 17761598 DOI: 10.1056/NEJMcibr073552  0.309
2007 Cheng IH, Scearce-Levie K, Legleiter J, Palop JJ, Gerstein H, Bien-Ly N, Puoliväli J, Lesné S, Ashe KH, Muchowski PJ, Mucke L. Accelerating amyloid-beta fibrillization reduces oligomer levels and functional deficits in Alzheimer disease mouse models. The Journal of Biological Chemistry. 282: 23818-28. PMID 17548355 DOI: 10.1074/Jbc.M701078200  0.38
2007 Ma H, Lesné S, Kotilinek L, Steidl-Nichols JV, Sherman M, Younkin L, Younkin S, Forster C, Sergeant N, Delacourte A, Vassar R, Citron M, Kofuji P, Boland LM, Ashe KH. Involvement of beta-site APP cleaving enzyme 1 (BACE1) in amyloid precursor protein-mediated enhancement of memory and activity-dependent synaptic plasticity. Proceedings of the National Academy of Sciences of the United States of America. 104: 8167-72. PMID 17470798 DOI: 10.1073/Pnas.0609521104  0.318
2007 Berger Z, Roder H, Hanna A, Carlson A, Rangachari V, Yue M, Wszolek Z, Ashe K, Knight J, Dickson D, Andorfer C, Rosenberry TL, Lewis J, Hutton M, Janus C. Accumulation of pathological tau species and memory loss in a conditional model of tauopathy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 3650-62. PMID 17409229 DOI: 10.1523/Jneurosci.0587-07.2007  0.383
2007 Ashe KH. Cognitive impairment in transgenic Aβ and tau models of alzheimer's disease Alzheimer's Disease: Advances in Genetics, Molecular and Cellular Biology. 77-91. DOI: 10.1007/978-0-387-35135-3_5  0.497
2006 Lesné S, Koh MT, Kotilinek L, Kayed R, Glabe CG, Yang A, Gallagher M, Ashe KH. A specific amyloid-beta protein assembly in the brain impairs memory. Nature. 440: 352-7. PMID 16541076 DOI: 10.1038/Nature04533  0.465
2006 Carlson GA, Wilson C, Young R, Turner S, Westaway D, Ashe KH, Tsukamoto A, Eckert K, Dohse M, Patel P, Tushinski R, Tamaki S, Uchida N. P4-370: Long-term survival of human CNS stem cells and their progeny in immunodeficient, plaque-producing APP transgenic mice Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.2111  0.308
2006 Hyman BT, Spires T, Matsui T, Orne J, Pitstik R, Carlson GA, Ashe K. S2-02-05: Neuritic alterations and dysfunctions in Alzheimer's disease Alzheimer's & Dementia. 2: S26-S26. DOI: 10.1016/J.Jalz.2006.05.085  0.373
2005 Ramsden M, Kotilinek L, Forster C, Paulson J, McGowan E, SantaCruz K, Guimaraes A, Yue M, Lewis J, Carlson G, Hutton M, Ashe KH. Age-dependent neurofibrillary tangle formation, neuron loss, and memory impairment in a mouse model of human tauopathy (P301L). The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 10637-47. PMID 16291936 DOI: 10.1523/Jneurosci.3279-05.2005  0.319
2005 Walsh DM, Klyubin I, Shankar GM, Townsend M, Fadeeva JV, Betts V, Podlisny MB, Cleary JP, Ashe KH, Rowan MJ, Selkoe DJ. The role of cell-derived oligomers of Abeta in Alzheimer's disease and avenues for therapeutic intervention. Biochemical Society Transactions. 33: 1087-90. PMID 16246051 DOI: 10.1042/Bst20051087  0.363
2005 Ashe KH. Mechanisms of memory loss in Aβ and tau mouse models Biochemical Society Transactions. 33: 591-594. PMID 16042551 DOI: 10.1042/BST0330591  0.437
2005 Cleary JP, Walsh DM, Hofmeister JJ, Shankar GM, Kuskowski MA, Selkoe DJ, Ashe KH. Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function. Nature Neuroscience. 8: 79-84. PMID 15608634 DOI: 10.1038/Nn1372  0.399
2004 Calon F, Lim GP, Yang F, Morihara T, Teter B, Ubeda O, Rostaing P, Triller A, Salem N, Ashe KH, Frautschy SA, Cole GM. Docosahexaenoic acid protects from dendritic pathology in an Alzheimer's disease mouse model. Neuron. 43: 633-45. PMID 15339646 DOI: 10.1016/j.neuron.2004.08.013  0.322
2004 Krezowski J, Knudson D, Ebeling C, Pitstick R, Giri RK, Schenk D, Westaway D, Younkin L, Younkin SG, Ashe KH, Carlson GA. Identification of loci determining susceptibility to the lethal effects of amyloid precursor protein transgene overexpression. Human Molecular Genetics. 13: 1989-97. PMID 15254013 DOI: 10.1093/Hmg/Ddh210  0.426
2004 Kawarabayashi T, Shoji M, Younkin LH, Wen-Lang L, Dickson DW, Murakami T, Matsubara E, Abe K, Ashe KH, Younkin SG. Dimeric amyloid beta protein rapidly accumulates in lipid rafts followed by apolipoprotein E and phosphorylated tau accumulation in the Tg2576 mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 3801-9. PMID 15084661 DOI: 10.1523/Jneurosci.5543-03.2004  0.413
2004 Kotilinek LA, Wang Q, Westerman mA, Lim GP, Falinska A, Simonyi A, Younkin LH, Younkin SG, Sun GY, Rowan M, Cleary J, Frautschy SA, Cole GM, Anwyl R, Ashe KH. P4-368 NSAIDS improve amyloid beta protein-induced deficits in memory and synaptic plasticity Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81926-2  0.348
2004 Lim GP, Calon F, Yang F, Morihara T, Ubeda O, Ashe KH, Frautschy SA, Cole GM. P4-334 Omega-3 fatty acid enriched diet reduces amyloid in an Alzheimer's disease mouse model Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81892-X  0.422
2004 Walsh DM, Kylubin I, Cleary JP, Townsend TM, Shankar GM, Podlisny MB, Fadeeva JV, Anwyl R, Ashe KH, Rowan MJ, Selkoe DJ. P1-230 Natural, cell-derived Aβ oligomers: their production, biological activity and inhibition Neurobiology of Aging. 25: S161-S162. DOI: 10.1016/S0197-4580(04)80543-8  0.347
2004 Cole GM, Zhao L, Calon F, Morihara T, Teter B, Ambegaokar S, Yang F, Ashe KH, Frautschy SA. O4-03-05 Dietary omega-3 docosahexaenoic acid DHA regulates CNS insulin signaling and related kinase pathways involved in actin assembly, synaptic plasticity and memory in an Alzheimer (AD) model Neurobiology of Aging. 25: S79. DOI: 10.1016/S0197-4580(04)80268-9  0.355
2004 Ashe KH. PL-4-3 Animal models of AD Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80224-0  0.4
2002 Kotilinek LA, Bacskai B, Westerman M, Kawarabayashi T, Younkin L, Hyman BT, Younkin S, Ashe KH. Reversible memory loss in a mouse transgenic model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 6331-5. PMID 12151510  0.364
2002 Westerman MA, Cooper-Blacketer D, Mariash A, Kotilinek L, Kawarabayashi T, Younkin LH, Carlson GA, Younkin SG, Ashe KH. The relationship between Abeta and memory in the Tg2576 mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 1858-67. PMID 11880515  0.328
2002 Westerman MA, Cooper-Blacketer D, Mariash A, Kotilinek L, Kawarabayashi T, Younkin LH, Carlson GA, Younkin SG, Ashe KH. The Relationship between Aβ and Memory in the Tg2576 Mouse Model of Alzheimer's Disease The Journal of Neuroscience. 22: 1858-1867. DOI: 10.1523/Jneurosci.22-05-01858.2002  0.432
2001 Ashe KH. Learning and memory in transgenic mice modeling Alzheimer's disease Learning and Memory. 8: 301-308. PMID 11773429 DOI: 10.1101/Lm.43701  0.544
2001 Dineley KT, Westerman M, Bui D, Bell K, Ashe KH, Sweatt JD. Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 4125-33. PMID 11404397  0.354
2001 Kawarabayashi T, Younkin LH, Saido TC, Shoji M, Ashe KH, Younkin SG. Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 372-81. PMID 11160418  0.396
2000 Ashe KH. Synaptic structure and function in transgenic APP mice Annals of the New York Academy of Sciences. 924: 39-41. PMID 11193800 DOI: 10.1111/J.1749-6632.2000.Tb05558.X  0.405
2000 Niwa K, Younkin L, Ebeling C, Turner SK, Westaway D, Younkin S, Ashe KH, Carlson GA, Iadecola C. Aβ1-40-related reduction in functional hyperemia in mouse neocortex during somatosensory activation Proceedings of the National Academy of Sciences of the United States of America. 97: 9735-9740. PMID 10944232 DOI: 10.1073/Pnas.97.17.9735  0.445
2000 Lim GP, Yang F, Chu T, Chen P, Beech W, Teter B, Tran T, Ubeda O, Ashe KH, Frautschy SA, Cole GM. Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 5709-14. PMID 10908610 DOI: 10.1523/Jneurosci.20-15-05709.2000  0.447
2000 Holtzman DM, Fagan AM, Mackey B, Tenkova T, Sartorius L, Paul SM, Bales K, Ashe KH, Irizarry MC, Hyman BT. Apolipoprotein E facilitates neuritic and cerebrovascular plaque formation in an Alzheimer's disease model. Annals of Neurology. 47: 739-47. PMID 10852539 DOI: 10.1002/1531-8249(200006)47:6<739::Aid-Ana6>3.0.Co;2-8  0.513
2000 Yang F, Uéda K, Chen PP, Ashe KH, Cole GM. Plaque-associated α-synuclein (NACP) pathology in aged transgenic mice expressing amyloid precursor protein Brain Research. 853: 381-383. PMID 10640638 DOI: 10.1016/S0006-8993(99)02207-6  0.403
2000 Holtzman DM, Fagan AM, Bales KR, DeMattos R, Irizarry MC, Ashe KH, Hyman BT, Paul SM. Role of APOE in Alzheimer's disease-like neurodegeneration Neurobiology of Aging. 21: 138-139. DOI: 10.1016/S0197-4580(00)82422-7  0.429
1999 Benzing WC, Wujek JR, Ward EK, Shaffer D, Ashe KH, Younkin SG, Brunden KR. Evidence for glial-mediated inflammation in aged APP(SW) transgenic mice. Neurobiology of Aging. 20: 581-9. PMID 10674423 DOI: 10.1016/S0197-4580(99)00065-2  0.428
1999 Shi J, Perry G, Aliev G, Smith MA, Ashe KH, Friedland RP. Serum amyloid P is not present in amyloid beta deposits of a transgenic animal model. Neuroreport. 10: 3229-32. PMID 10574565 DOI: 10.1097/00001756-199910190-00019  0.438
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