| Year |
Citation |
Score |
| 2022 |
Dou W, Malhi M, Cui T, Wang M, Wang T, Shan G, Law J, Gong Z, Plakhotnik J, Filleter T, Li R, Simmons CA, Maynes JT, Sun Y. A Carbon-Based Biosensing Platform for Simultaneously Measuring the Contraction and Electrophysiology of iPSC-Cardiomyocyte Monolayers. Acs Nano. PMID 35715006 DOI: 10.1021/acsnano.2c04676 |
0.319 |
|
| 2022 |
Dou W, Malhi M, Zhao Q, Wang L, Huang Z, Law J, Liu N, Simmons CA, Maynes JT, Sun Y. Microengineered platforms for characterizing the contractile function of in vitro cardiac models. Microsystems & Nanoengineering. 8: 26. PMID 35299653 DOI: 10.1038/s41378-021-00344-0 |
0.366 |
|
| 2021 |
Liu H, Usprech JF, Parameshwar PK, Sun Y, Simmons CA. Combinatorial screen of dynamic mechanical stimuli for predictive control of MSC mechano-responsiveness. Science Advances. 7. PMID 33962940 DOI: 10.1126/sciadv.abe7204 |
0.687 |
|
| 2020 |
Dou W, Wang L, Malhi M, Liu H, Zhao Q, Plakhotnik J, Xu Z, Huang Z, Simmons CA, Maynes JT, Sun Y. A microdevice platform for characterizing the effect of mechanical strain magnitudes on the maturation of iPSC-Cardiomyocytes. Biosensors & Bioelectronics. 112875. PMID 33303322 DOI: 10.1016/j.bios.2020.112875 |
0.695 |
|
| 2020 |
Chung JC, Wong E, Tang M, Eliathamby D, Forbes TL, Butany J, Simmons CA, Ouzounian M. Biomechanics of Aortic Dissection: A Comparison of Aortas Associated With Bicuspid and Tricuspid Aortic Valves. Journal of the American Heart Association. 9: e016715. PMID 32750292 DOI: 10.1161/Jaha.120.016715 |
0.324 |
|
| 2020 |
Ngai D, Lino M, Rothenberg KE, Simmons CA, Fernandez-Gonzalez R, Bendeck MP. DDR1 (Discoidin Domain Receptor-1)-RhoA Axis Senses Matrix Stiffness to Promote Vascular Calcification. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120314697. PMID 32493168 DOI: 10.1161/Atvbaha.120.314697 |
0.343 |
|
| 2020 |
Moyle LA, Cheng RY, Liu H, Davoudi S, Ferreira SA, Nissar AA, Sun Y, Gentleman E, Simmons CA, Gilbert PM. Three-dimensional niche stiffness synergizes with Wnt7a to modulate the extent of satellite cell symmetric self-renewal divisions. Molecular Biology of the Cell. mbcE20010078. PMID 32491970 DOI: 10.1091/Mbc.E20-01-0078 |
0.701 |
|
| 2020 |
Ireland RG, Kibschull M, Audet J, Ezzo M, Hinz B, Lye SJ, Simmons CA. Combinatorial extracellular matrix microarray identifies novel bioengineered substrates for xeno-free culture of human pluripotent stem cells. Biomaterials. 248: 120017. PMID 32283392 DOI: 10.1016/J.Biomaterials.2020.120017 |
0.345 |
|
| 2019 |
Zhang X, Simmons CA, Santerre JP. Paracrine signalling of monocytes enables desirable extracellular matrix accumulation and temporally appropriate phenotype of vascular smooth muscle cell-like cells derived from adipose stromal cells. Acta Biomaterialia. PMID 31821896 DOI: 10.1016/J.Actbio.2019.12.006 |
0.383 |
|
| 2019 |
Shridhar A, Lam AYL, Sun Y, Simmons CA, Gillies ER, Flynn LE. Culture on tissue-specific Coatings Derived from α-amylase-digested Decellularized Adipose Tissue Enhances the Proliferation and Adipogenic Differentiation of Human adipose-derived Stromal Cells. Biotechnology Journal. e1900118. PMID 31657515 DOI: 10.1002/Biot.201900118 |
0.42 |
|
| 2019 |
Wong JF, Mohan MD, Young EWK, Simmons CA. Integrated electrochemical measurement of endothelial permeability in a 3D hydrogel-based microfluidic vascular model. Biosensors & Bioelectronics. 147: 111757. PMID 31654819 DOI: 10.1016/J.Bios.2019.111757 |
0.328 |
|
| 2019 |
Beca B, Sun Y, Wong E, Moraes C, Simmons CA. Dynamic bioreactors with integrated microfabricated devices for mechanobiological screening. Tissue Engineering. Part C, Methods. PMID 31337285 DOI: 10.1089/Ten.Tec.2019.0121 |
0.476 |
|
| 2019 |
Xin L, Yao W, Peng Y, Lu P, Ribeiro R, Wei B, Gellner B, Simmons C, Zu J, Sun Y, Badiwala M. Primed Left Ventricle Heart Perfusion Creates Physiological Aortic Pressure in Porcine Hearts. Asaio Journal (American Society For Artificial Internal Organs : 1992). PMID 30893130 DOI: 10.1097/Mat.0000000000000947 |
0.375 |
|
| 2019 |
Wong JF, Simmons CA. Microfluidic assay for the on-chip electrochemical measurement of cell monolayer permeability. Lab On a Chip. PMID 30778462 DOI: 10.1039/C8Lc01321G |
0.324 |
|
| 2018 |
Zhang X, Simmons CA, Santerre JP. Alterations of MEK1/2-ERK1/2, IFNγ and Smad2/3 associated Signalling pathways during cryopreservation of ASCs affect their differentiation towards VSMC-like cells. Stem Cell Research. 32: 115-125. PMID 30273905 DOI: 10.1016/J.Scr.2018.09.005 |
0.353 |
|
| 2018 |
Fitzsimmons REB, Mazurek MS, Soos A, Simmons CA. Mesenchymal Stromal/Stem Cells in Regenerative Medicine and Tissue Engineering. Stem Cells International. 2018: 8031718. PMID 30210552 DOI: 10.1155/2018/8031718 |
0.354 |
|
| 2018 |
Wang L, Dou W, Malhi M, Zhu M, Liu H, Plakhotnik J, Xu Z, Zhao Q, Chen J, Chen S, Hamilton R, Simmons CA, Maynes JT, Sun Y. A Micro Device Platform for Continuous Measurement of Contractility, Beating Rate, and Beating Rhythm of hiPSC-Cardiomyocytes inside a Controlled Incubator Environment. Acs Applied Materials & Interfaces. PMID 29874032 DOI: 10.1021/Acsami.8B05407 |
0.682 |
|
| 2018 |
Simmons CA, Jo H. Correction to: Editorial: Special Issue on Heart Valve Mechanobiology : New Insights into Mechanical Regulation of Valve Disease and Regeneration. Cardiovascular Engineering and Technology. PMID 29797229 DOI: 10.1007/S13239-018-0365-Y |
0.35 |
|
| 2018 |
Wang X, Liu H, Zhu M, Cao C, Xu Z, Tsatskis Y, Lau K, Kuok C, Filleter T, McNeill H, Simmons CA, Hopyan S, Sun Y. Mechanical stability of the cell nucleus: roles played by the cytoskeleton in nuclear deformation and strain recovery. Journal of Cell Science. PMID 29777038 DOI: 10.1242/Jcs.209627 |
0.683 |
|
| 2018 |
Zhong A, Mirzaei Z, Simmons CA. The Roles of Matrix Stiffness and ß-Catenin Signaling in Endothelial-to-Mesenchymal Transition of Aortic Valve Endothelial Cells. Cardiovascular Engineering and Technology. PMID 29761409 DOI: 10.1007/S13239-018-0363-0 |
0.363 |
|
| 2018 |
Simmons CA, Jo H. Editorial: Special Issue on Heart Valve Mechanobiology : New Insights into Mechanical Regulation of Valve Disease and Regeneration. Cardiovascular Engineering and Technology. PMID 29761407 DOI: 10.1007/S13239-018-0360-3 |
0.367 |
|
| 2018 |
Liu H, MacQueen LA, Usprech JF, Maleki H, Sider KL, Doyle MG, Sun Y, Simmons CA. Microdevice arrays with strain sensors for 3D mechanical stimulation and monitoring of engineered tissues. Biomaterials. 172: 30-40. PMID 29715593 DOI: 10.1016/J.Biomaterials.2018.04.041 |
0.779 |
|
| 2018 |
Chung J, Wong E, Forbes T, Butany J, Simmons C, Ouzounian M. Aortic Aneurysms Have Distinct Mechanical Phenotypes Based On Valve Morphology Canadian Journal of Cardiology. 34. DOI: 10.1016/J.Cjca.2018.07.305 |
0.347 |
|
| 2018 |
Zhang X, Simmons CA, Santerre JP. Influence of Cryopreservation on the Differentiation of Adipose Derived Stromal Cells Towards Vascular Smooth Muscle Cells Atherosclerosis Supplements. 32: 143-144. DOI: 10.1016/J.Atherosclerosissup.2018.04.441 |
0.319 |
|
| 2018 |
Zhong A, Simmons CA. Mechanical Strain-induced Reactive Oxygen Species and Their Role in Valve Interstitial Cell Calcification Atherosclerosis Supplements. 32: 107. DOI: 10.1016/J.Atherosclerosissup.2018.04.327 |
0.336 |
|
| 2018 |
Adams RL, McFadden MJ, Bernknopf B, Simmons CA. Shear Stress-Regulation of C-Type Natriuretic Peptide Signaling in Aortic Valve Disease Atherosclerosis Supplements. 32: 85. DOI: 10.1016/J.Atherosclerosissup.2018.04.260 |
0.328 |
|
| 2018 |
Lam AY, Mirzaei Z, Wei K, Simmons CA. FHL2-RhoA Signalling Regulates Mechanically Induced Aortic Valve Interstitial Cell Osteogenic Differentiation Atherosclerosis Supplements. 32: 2. DOI: 10.1016/J.Atherosclerosissup.2018.04.006 |
0.397 |
|
| 2017 |
Safaee H, Bakooshli MA, Davoudi S, Cheng RY, Martowirogo AJ, Li EW, Simmons CA, Gilbert PM. Tethered Jagged-1 Synergizes with Culture Substrate Stiffness to Modulate Notch-Induced Myogenic Progenitor Differentiation. Cellular and Molecular Bioengineering. 10: 501-513. PMID 31719873 DOI: 10.1007/S12195-017-0506-7 |
0.352 |
|
| 2017 |
Blaser MC, Wei K, Adams RL, Zhou YQ, Caruso LL, Mirzaei Z, Lam A, Tam RK, Zhang H, Heximer SP, Henkelman M, Simmons CA. Deficiency of Natriuretic Peptide Receptor 2 Promotes Bicuspid Aortic Valves, Aortic Valve Disease, Left Ventricular Dysfunction, and Ascending Aortic Dilatations in Mice. Circulation Research. PMID 29273600 DOI: 10.1161/Circresaha.117.311194 |
0.374 |
|
| 2017 |
Zhang X, Bendeck MP, Simmons CA, Santerre JP. Deriving vascular smooth muscle cells from mesenchymal stromal cells: Evolving differentiation strategies and current understanding of their mechanisms. Biomaterials. 145: 9-22. PMID 28843066 DOI: 10.1016/J.Biomaterials.2017.08.028 |
0.372 |
|
| 2017 |
Wen J, Tao H, Lau K, Liu H, Simmons CA, Sun Y, Hopyan S. Cell and Tissue Scale Forces Coregulate Fgfr2-Dependent Tetrads and Rosettes in the Mouse Embryo. Biophysical Journal. 112: 2209-2218. PMID 28538157 DOI: 10.1016/J.Bpj.2017.04.024 |
0.702 |
|
| 2017 |
Usprech J, Romero DA, Amon CH, Simmons CA. Combinatorial screening of 3D biomaterial properties that promote myofibrogenesis for mesenchymal stromal cell-based heart valve tissue engineering. Acta Biomaterialia. PMID 28532900 DOI: 10.1016/J.Actbio.2017.05.044 |
0.399 |
|
| 2017 |
Zhang X, Battiston KG, Labow RS, Simmons CA, Santerre JP. Generating favourable growth factor and protease release profiles to enable extracellular matrix accumulation within an in vitro tissue engineering environment. Acta Biomaterialia. PMID 28242454 DOI: 10.1016/J.Actbio.2017.02.041 |
0.332 |
|
| 2017 |
Zhang X, Battiston KG, Simmons CA, Santerre JP. Differential Regulation of Extracellular Matrix Components Using Different Vitamin C Derivatives in Mono- and Coculture Systems Acs Biomaterials Science & Engineering. 4: 3768-3778. DOI: 10.1021/Acsbiomaterials.7B00389 |
0.379 |
|
| 2016 |
Loai S, Haedicke I, Mirzaei Z, Simmons CA, Zhang XA, Cheng HM. Positive-contrast cellular MRI of embryonic stem cells for tissue regeneration using a highly efficient T1 MRI contrast agent. Journal of Magnetic Resonance Imaging : Jmri. PMID 27185221 DOI: 10.1002/Jmri.25299 |
0.306 |
|
| 2016 |
Usprech J, Chen WL, Simmons CA. Heart valve regeneration: the need for systems approaches. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. PMID 26862013 DOI: 10.1002/Wsbm.1329 |
0.417 |
|
| 2016 |
Liu H, Simmons CA, Sun Y. A microfabricated platform with on-chip strain sensing and hydrogel arrays for 3D mechanical stimulation of cells Proceedings of the Ieee International Conference On Micro Electro Mechanical Systems (Mems). 2016: 267-270. DOI: 10.1109/MEMSYS.2016.7421611 |
0.674 |
|
| 2015 |
Liu H, Usprech J, Sun Y, Simmons CA. A microfabricated platform with hydrogel arrays for 3D mechanical stimulation of cells. Acta Biomaterialia. PMID 26646540 DOI: 10.1016/J.Actbio.2015.11.054 |
0.711 |
|
| 2015 |
Nejad SP, Blaser MC, Paul Santerre J, Caldarone CA, Simmons CA. Biomechanical conditioning of tissue engineered heart valves: Too much of a good thing? Advanced Drug Delivery Reviews. PMID 26555371 DOI: 10.1016/J.Addr.2015.11.003 |
0.416 |
|
| 2015 |
Kheradvar A, Groves EM, Falahatpisheh A, Mofrad MK, Hamed Alavi S, Tranquillo R, Dasi LP, Simmons CA, Jane Grande-Allen K, Goergen CJ, Baaijens F, Little SH, Canic S, Griffith B. Emerging Trends in Heart Valve Engineering: Part IV. Computational Modeling and Experimental Studies. Annals of Biomedical Engineering. 43: 2314-33. PMID 26224522 DOI: 10.1007/S10439-015-1394-4 |
0.316 |
|
| 2015 |
Ireland RG, Simmons CA. Human Pluripotent Stem Cell Mechanobiology: Manipulating the Biophysical Microenvironment for Regenerative Medicine and Tissue Engineering Applications. Stem Cells (Dayton, Ohio). PMID 26189759 DOI: 10.1002/Stem.2105 |
0.369 |
|
| 2015 |
Battiston KG, Labow RS, Simmons CA, Santerre JP. Immunomodulatory polymeric scaffold enhances extracellular matrix production in cell co-cultures under dynamic mechanical stimulation. Acta Biomaterialia. PMID 26093069 DOI: 10.1016/J.Actbio.2015.05.038 |
0.377 |
|
| 2015 |
Plaza GR, Uyeda TQ, Mirzaei Z, Simmons CA. Study of the influence of actin-binding proteins using linear analyses of cell deformability. Soft Matter. 11: 5435-46. PMID 26059185 DOI: 10.1039/C5Sm00125K |
0.315 |
|
| 2015 |
Lau K, Tao H, Liu H, Wen J, Sturgeon K, Sorfazlian N, Lazic S, Burrows JT, Wong MD, Li D, Deimling S, Ciruna B, Scott I, Simmons C, Henkelman RM, et al. Anisotropic stress orients remodelling of mammalian limb bud ectoderm. Nature Cell Biology. 17: 569-79. PMID 25893915 DOI: 10.1038/Ncb3156 |
0.688 |
|
| 2015 |
Kheradvar A, Groves EM, Dasi LP, Alavi SH, Tranquillo R, Grande-Allen KJ, Simmons CA, Griffith B, Falahatpisheh A, Goergen CJ, Mofrad MR, Baaijens F, Little SH, Canic S. Emerging trends in heart valve engineering: Part I. Solutions for future. Annals of Biomedical Engineering. 43: 833-43. PMID 25488074 DOI: 10.1007/S10439-014-1209-Z |
0.371 |
|
| 2015 |
Kheradvar A, Groves EM, Goergen CJ, Alavi SH, Tranquillo R, Simmons CA, Dasi LP, Grande-Allen KJ, Mofrad MR, Falahatpisheh A, Griffith B, Baaijens F, Little SH, Canic S. Emerging trends in heart valve engineering: Part II. Novel and standard technologies for aortic valve replacement. Annals of Biomedical Engineering. 43: 844-57. PMID 25449148 DOI: 10.1007/S10439-014-1191-5 |
0.34 |
|
| 2015 |
Mohammadi H, Arora PD, Simmons CA, Janmey PA, McCulloch CA. Inelastic behaviour of collagen networks in cell-matrix interactions and mechanosensation. Journal of the Royal Society, Interface / the Royal Society. 12: 20141074. PMID 25392399 DOI: 10.1098/Rsif.2014.1074 |
0.35 |
|
| 2015 |
Kheradvar A, Groves EM, Simmons CA, Griffith B, Alavi SH, Tranquillo R, Dasi LP, Falahatpisheh A, Grande-Allen KJ, Goergen CJ, Mofrad MR, Baaijens F, Canic S, Little SH. Emerging trends in heart valve engineering: Part III. Novel technologies for mitral valve repair and replacement. Annals of Biomedical Engineering. 43: 858-70. PMID 25287646 DOI: 10.1007/S10439-014-1129-Y |
0.351 |
|
| 2015 |
Thavandiran N, Dubois N, Mikryukov A, Massé S, Beca B, Simmons CA, Deshpande VS, McGarry JP, Chen CS, Nanthakumar K, Keller GM, Radisic M, Zandstra PW. Correction: Design and formulation of functional pluripotent stem cell-derived cardiac microtissues (Proceedings of the National Academy of Sciences (2013) 110, (E4698-E4707) DOI:10.1073/pnas.1311120110) Proceedings of the National Academy of Sciences of the United States of America. 112: E3151. DOI: 10.1073/Pnas.1311120110). |
0.428 |
|
| 2014 |
Sider KL, Zhu C, Kwong AV, Mirzaei Z, de Langé CF, Simmons CA. Evaluation of a porcine model of early aortic valve sclerosis. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 23: 289-97. PMID 24998316 DOI: 10.1016/J.Carpath.2014.05.004 |
0.763 |
|
| 2014 |
Liu H, Wen J, Xiao Y, Liu J, Hopyan S, Radisic M, Simmons CA, Sun Y. In situ mechanical characterization of the cell nucleus by atomic force microscopy. Acs Nano. 8: 3821-8. PMID 24673613 DOI: 10.1021/Nn500553Z |
0.7 |
|
| 2014 |
Battiston KG, Ouyang B, Labow RS, Simmons CA, Santerre JP. Monocyte/macrophage cytokine activity regulates vascular smooth muscle cell function within a degradable polyurethane scaffold. Acta Biomaterialia. 10: 1146-55. PMID 24361424 DOI: 10.1016/J.Actbio.2013.12.022 |
0.304 |
|
| 2014 |
Xiao Y, Zhang B, Liu H, Miklas JW, Gagliardi M, Pahnke A, Thavandiran N, Sun Y, Simmons C, Keller G, Radisic M. Microfabricated perfusable cardiac biowire: a platform that mimics native cardiac bundle. Lab On a Chip. 14: 869-82. PMID 24352498 DOI: 10.1039/C3Lc51123E |
0.695 |
|
| 2014 |
Liu H, Tan Q, Geddie WR, Jewett MA, Phillips N, Ke D, Simmons CA, Sun Y. Biophysical characterization of bladder cancer cells with different metastatic potential. Cell Biochemistry and Biophysics. 68: 241-6. PMID 23793959 DOI: 10.1007/S12013-013-9702-9 |
0.691 |
|
| 2014 |
Liu H, Wen J, Liu J, Hopyan S, Simmons C, Sun Y. Mechanical characterization of cancer cell nuclei in situ 9th Ieee International Conference On Nano/Micro Engineered and Molecular Systems, Ieee-Nems 2014. 669-673. DOI: 10.1109/NEMS.2014.6908900 |
0.636 |
|
| 2013 |
Thavandiran N, Dubois N, Mikryukov A, Massé S, Beca B, Simmons CA, Deshpande VS, McGarry JP, Chen CS, Nanthakumar K, Keller GM, Radisic M, Zandstra PW. Design and formulation of functional pluripotent stem cell-derived cardiac microtissues. Proceedings of the National Academy of Sciences of the United States of America. 110: E4698-707. PMID 24255110 DOI: 10.1073/Pnas.1311120110 |
0.511 |
|
| 2013 |
Heckler AF, Mirzaei Z, Pereira I, Simmons CA, Gong SG. Development of a three-dimensional in vitro model system to study orthodontic tooth movement Archives of Oral Biology. 58: 1498-1510. PMID 23845751 DOI: 10.1016/J.Archoralbio.2013.06.011 |
0.323 |
|
| 2013 |
Gould ST, Srigunapalan S, Simmons CA, Anseth KS. Hemodynamic and cellular response feedback in calcific aortic valve disease. Circulation Research. 113: 186-97. PMID 23833293 DOI: 10.1161/Circresaha.112.300154 |
0.415 |
|
| 2013 |
Liu H, Sun Y, Simmons CA. Determination of local and global elastic moduli of valve interstitial cells cultured on soft substrates. Journal of Biomechanics. 46: 1967-71. PMID 23746597 DOI: 10.1016/J.Jbiomech.2013.05.001 |
0.73 |
|
| 2013 |
MacQueen L, Sun Y, Simmons CA. Mesenchymal stem cell mechanobiology and emerging experimental platforms. Journal of the Royal Society, Interface / the Royal Society. 10: 20130179. PMID 23635493 DOI: 10.1098/Rsif.2013.0179 |
0.457 |
|
| 2013 |
Chen MB, Srigunapalan S, Wheeler AR, Simmons CA. A 3D microfluidic platform incorporating methacrylated gelatin hydrogels to study physiological cardiovascular cell-cell interactions. Lab On a Chip. 13: 2591-8. PMID 23525275 DOI: 10.1039/C3Lc00051F |
0.403 |
|
| 2013 |
Moraes C, Likhitpanichkul M, Lam CJ, Beca BM, Sun Y, Simmons CA. Microdevice array-based identification of distinct mechanobiological response profiles in layer-specific valve interstitial cells. Integrative Biology : Quantitative Biosciences From Nano to Macro. 5: 673-80. PMID 23403640 DOI: 10.1039/C3Ib20254B |
0.506 |
|
| 2013 |
Zhao R, Simmons CA. A simple method to estimate the exponential material parameters of heart valve tissue based on analogy between uniaxial tension and micropipette aspiration. Biomechanics and Modeling in Mechanobiology. 12: 1283-90. PMID 23355188 DOI: 10.1007/S10237-013-0470-7 |
0.549 |
|
| 2012 |
Al-Haque S, Miklas JW, Feric N, Chiu LL, Chen WL, Simmons CA, Radisic M. Hydrogel substrate stiffness and topography interact to induce contact guidance in cardiac fibroblasts. Macromolecular Bioscience. 12: 1342-53. PMID 22927323 DOI: 10.1002/Mabi.201200042 |
0.338 |
|
| 2012 |
MacQueen L, Chebotarev O, Simmons CA, Sun Y. Miniaturized platform with on-chip strain sensors for compression testing of arrayed materials. Lab On a Chip. 12: 4178-84. PMID 22885688 DOI: 10.1039/C2Lc40670E |
0.38 |
|
| 2012 |
Wyss K, Yip CY, Mirzaei Z, Jin X, Chen JH, Simmons CA. The elastic properties of valve interstitial cells undergoing pathological differentiation. Journal of Biomechanics. 45: 882-7. PMID 22189247 DOI: 10.1016/J.Jbiomech.2011.11.030 |
0.646 |
|
| 2012 |
Srigunapalan S, Eydelnant IA, Simmons CA, Wheeler AR. A digital microfluidic platform for primary cell culture and analysis. Lab On a Chip. 12: 369-75. PMID 22094822 DOI: 10.1039/C1Lc20844F |
0.325 |
|
| 2012 |
Zhao R, Simmons CA. An improved texture correlation algorithm to measure substrate-cytoskeletal network strain transfer under large compressive strain. Journal of Biomechanics. 45: 76-82. PMID 22030122 DOI: 10.1016/J.Jbiomech.2011.10.003 |
0.556 |
|
| 2012 |
Sider KL, Kwong AV, Wei B, Simmons CA. Characterization of Early Porcine Aortic Valve Disease Qscience Proceedings. 2012: 9. DOI: 10.5339/qproc.2012.heartvalve.4.9 |
0.754 |
|
| 2012 |
Blaser MC, Sider KL, Kwong AV, Zhou Y, Henkelman RM, Simmons CA. Proteoglycan-Rich Leaflet Thickening in Diet-Induced Early Aortic Valve Disease Qscience Proceedings. 2012: 59. DOI: 10.5339/qproc.2012.heartvalve.4.59 |
0.751 |
|
| 2012 |
Blaser M, Kwon JW, Sider KL, Kwong AV, Wei K, Simmons CA. C-type Natriuretic Peptide Modulates TGF-β1-induced Synthesis of Proteoglycan by VICs Qscience Proceedings. 2012: 19. DOI: 10.5339/qproc.2012.heartvalve.4.19 |
0.716 |
|
| 2012 |
Liu H, Simmons CA, Sun Y. Characterization of the elasticity of valve interstitial cells on soft substrates using atomic force microscopy Asme 2012 Summer Bioengineering Conference, Sbc 2012. 831-832. DOI: 10.1115/SBC2012-80369 |
0.661 |
|
| 2012 |
Blaser M, Sider K, Kwong A, Zhou Y, Henkelman R, Simmons C. 719 Proteoglycan-Rich Leaflet Thickening in Diet-Induced Early Aortic Valve Disease in Mice Canadian Journal of Cardiology. 28: S375. DOI: 10.1016/J.Cjca.2012.07.651 |
0.756 |
|
| 2012 |
Liu J, Moraes C, Lu Z, Simmons C, Sun Y. Single Cell Deposition Methods in Cell Biology. 112: 403-420. DOI: 10.1016/B978-0-12-405914-6.00023-8 |
0.329 |
|
| 2011 |
Rajamannan NM, Evans FJ, Aikawa E, Grande-Allen KJ, Demer LL, Heistad DD, Simmons CA, Masters KS, Mathieu P, O'Brien KD, Schoen FJ, Towler DA, Yoganathan AP, Otto CM. Calcific aortic valve disease: not simply a degenerative process: A review and agenda for research from the National Heart and Lung and Blood Institute Aortic Stenosis Working Group. Executive summary: Calcific aortic valve disease-2011 update. Circulation. 124: 1783-91. PMID 22007101 DOI: 10.1161/Circulationaha.110.006767 |
0.338 |
|
| 2011 |
Moraes C, Sun Y, Simmons CA. (Micro)managing the mechanical microenvironment. Integrative Biology : Quantitative Biosciences From Nano to Macro. 3: 959-71. PMID 21931883 DOI: 10.1039/C1Ib00056J |
0.449 |
|
| 2011 |
Sider KL, Blaser MC, Simmons CA. Animal models of calcific aortic valve disease. International Journal of Inflammation. 2011: 364310. PMID 21826258 DOI: 10.4061/2011/364310 |
0.759 |
|
| 2011 |
Chen JH, Simmons CA. Cell-matrix interactions in the pathobiology of calcific aortic valve disease: critical roles for matricellular, matricrine, and matrix mechanics cues. Circulation Research. 108: 1510-24. PMID 21659654 DOI: 10.1161/Circresaha.110.234237 |
0.631 |
|
| 2011 |
Yip CY, Blaser MC, Mirzaei Z, Zhong X, Simmons CA. Inhibition of pathological differentiation of valvular interstitial cells by C-type natriuretic peptide. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 1881-9. PMID 21617139 DOI: 10.1161/Atvbaha.111.223974 |
0.399 |
|
| 2011 |
Srigunapalan S, Lam C, Wheeler AR, Simmons CA. A microfluidic membrane device to mimic critical components of the vascular microenvironment. Biomicrofluidics. 5: 13409. PMID 21522499 DOI: 10.1063/1.3530598 |
0.34 |
|
| 2011 |
Sharifpoor S, Simmons CA, Labow RS, Paul Santerre J. Functional characterization of human coronary artery smooth muscle cells under cyclic mechanical strain in a degradable polyurethane scaffold. Biomaterials. 32: 4816-29. PMID 21463894 DOI: 10.1016/J.Biomaterials.2011.03.034 |
0.369 |
|
| 2011 |
Yip CY, Simmons CA. The aortic valve microenvironment and its role in calcific aortic valve disease. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 20: 177-82. PMID 21256052 DOI: 10.1016/J.Carpath.2010.12.001 |
0.385 |
|
| 2011 |
Chen WL, Simmons CA. Lessons from (patho)physiological tissue stiffness and their implications for drug screening, drug delivery and regenerative medicine. Advanced Drug Delivery Reviews. 63: 269-76. PMID 21241759 DOI: 10.1016/J.Addr.2011.01.004 |
0.38 |
|
| 2011 |
Chen JH, Chen WL, Sider KL, Yip CY, Simmons CA. β-catenin mediates mechanically regulated, transforming growth factor-β1-induced myofibroblast differentiation of aortic valve interstitial cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 590-7. PMID 21127288 DOI: 10.1161/Atvbaha.110.220061 |
0.776 |
|
| 2011 |
Zhao R, Sider KL, Simmons CA. Measurement of layer-specific mechanical properties in multilayered biomaterials by micropipette aspiration. Acta Biomaterialia. 7: 1220-7. PMID 21056128 DOI: 10.1016/J.Actbio.2010.11.004 |
0.76 |
|
| 2011 |
Lu Z, Moraes C, Ye G, Simmons CA, Sun Y. Correction: Single Cell Deposition and Patterning with a Robotic System Plos One. 6. DOI: 10.1371/Annotation/A67C3A69-Ce0C-49Bf-A592-761C3E741C73 |
0.328 |
|
| 2011 |
Moraes C, Zhao R, Likhitpanichkul M, Simmons CA, Sun Y. Semi-confined compression of microfabricated polymerized biomaterial constructs Journal of Micromechanics and Microengineering. 21. DOI: 10.1088/0960-1317/21/5/054014 |
0.578 |
|
| 2011 |
Blaser M, Sider K, Zhou Y, Henkelman M, Simmons C. 062 C-type natriuretic peptide is involved in proteoglycan-rich leaflet thickening in early aortic valve disease Canadian Journal of Cardiology. 27: S82-S83. DOI: 10.1016/J.Cjca.2011.07.055 |
0.759 |
|
| 2010 |
Moraes C, Sun Y, Simmons CA. Microfabricated platforms for mechanically dynamic cell culture. Journal of Visualized Experiments : Jove. PMID 21206477 DOI: 10.3791/2224 |
0.447 |
|
| 2010 |
Lu Z, Moraes C, Ye G, Simmons CA, Sun Y. Single cell deposition and patterning with a robotic system. Plos One. 5: e13542. PMID 21042403 DOI: 10.1371/Journal.Pone.0013542 |
0.402 |
|
| 2010 |
Sharifpoor S, Simmons CA, Labow RS, Santerre JP. A study of vascular smooth muscle cell function under cyclic mechanical loading in a polyurethane scaffold with optimized porosity. Acta Biomaterialia. 6: 4218-28. PMID 20601230 DOI: 10.1016/J.Actbio.2010.06.018 |
0.373 |
|
| 2010 |
Yuen A, Laschinger C, Talior I, Lee W, Chan M, Birek J, Young EW, Sivagurunathan K, Won E, Simmons CA, McCulloch CA. Methylglyoxal-modified collagen promotes myofibroblast differentiation. Matrix Biology : Journal of the International Society For Matrix Biology. 29: 537-48. PMID 20423729 DOI: 10.1016/J.Matbio.2010.04.004 |
0.347 |
|
| 2010 |
Moraes C, Chen JH, Sun Y, Simmons CA. Microfabricated arrays for high-throughput screening of cellular response to cyclic substrate deformation. Lab On a Chip. 10: 227-34. PMID 20066251 DOI: 10.1039/B914460A |
0.634 |
|
| 2010 |
Young EW, Simmons CA. Macro- and microscale fluid flow systems for endothelial cell biology. Lab On a Chip. 10: 143-60. PMID 20066241 DOI: 10.1039/B913390A |
0.315 |
|
| 2010 |
Chen WL, Likhitpanichkul M, Ho A, Simmons CA. Integration of statistical modeling and high-content microscopy to systematically investigate cell-substrate interactions. Biomaterials. 31: 2489-97. PMID 20034663 DOI: 10.1016/J.Biomaterials.2009.12.002 |
0.369 |
|
| 2010 |
Bhana B, Iyer RK, Chen WL, Zhao R, Sider KL, Likhitpanichkul M, Simmons CA, Radisic M. Influence of substrate stiffness on the phenotype of heart cells. Biotechnology and Bioengineering. 105: 1148-60. PMID 20014437 DOI: 10.1002/Bit.22647 |
0.782 |
|
| 2010 |
Moraes C, Wang G, Sun Y, Simmons CA. A microfabricated platform for high-throughput unconfined compression of micropatterned biomaterial arrays. Biomaterials. 31: 577-84. PMID 19819010 DOI: 10.1016/J.Biomaterials.2009.09.068 |
0.465 |
|
| 2010 |
Chen JH, Liu C, You L, Simmons CA. Boning up on Wolff's Law: mechanical regulation of the cells that make and maintain bone. Journal of Biomechanics. 43: 108-18. PMID 19818443 DOI: 10.1016/J.Jbiomech.2009.09.016 |
0.548 |
|
| 2010 |
Zhao R, Lin L, Simmons CA. The effects of cell contraction and loss of adhesion on the apoptosis of valve intersitial cells Asme 2010 Summer Bioengineering Conference, Sbc 2010. 969-970. DOI: 10.1115/SBC2010-19249 |
0.538 |
|
| 2010 |
Zhao R, Sider KL, Simmons CA. Comparison of analytical and finite element implementation of exponential constitutive models for valve tissue under micropipette aspiration Asme 2010 Summer Bioengineering Conference, Sbc 2010. 275-276. DOI: 10.1115/SBC2010-19245 |
0.767 |
|
| 2010 |
Rask F, Mihic A, Reis L, Dallabrida SM, Ismail NS, Sider K, Simmons CA, Rupnick MA, Weisel RD, Li RK, Radisic M. Hydrogels modified with QHREDGS peptide support cardiomyocyte survival in vitro and after sub-cutaneous implantation Soft Matter. 6: 5089-5099. DOI: 10.1039/C0Sm00362J |
0.766 |
|
| 2010 |
Moraes C, Wyss K, Brisson E, Keith BA, Sun Y, Simmons CA. An undergraduate lab (on-a-chip): Probing single cell mechanics on a microfluidic platform Cellular and Molecular Bioengineering. 3: 319-330. DOI: 10.1007/S12195-010-0124-0 |
0.318 |
|
| 2009 |
Zhao R, Wyss K, Simmons CA. Comparison of analytical and inverse finite element approaches to estimate cell viscoelastic properties by micropipette aspiration. Journal of Biomechanics. 42: 2768-73. PMID 19765713 DOI: 10.1016/J.Jbiomech.2009.07.035 |
0.569 |
|
| 2009 |
Moraes C, Kagoma YK, Beca BM, Tonelli-Zasarsky RL, Sun Y, Simmons CA. Integrating polyurethane culture substrates into poly(dimethylsiloxane) microdevices. Biomaterials. 30: 5241-50. PMID 19545891 DOI: 10.1016/J.Biomaterials.2009.05.066 |
0.427 |
|
| 2009 |
Simmons CA. Aortic valve mechanics: an emerging role for the endothelium. Journal of the American College of Cardiology. 53: 1456-8. PMID 19371830 DOI: 10.1016/J.Jacc.2008.12.052 |
0.344 |
|
| 2009 |
Yip CY, Chen JH, Zhao R, Simmons CA. Calcification by valve interstitial cells is regulated by the stiffness of the extracellular matrix. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 936-42. PMID 19304575 DOI: 10.1161/Atvbaha.108.182394 |
0.716 |
|
| 2009 |
Chen JH, Yip CY, Sone ED, Simmons CA. Identification and characterization of aortic valve mesenchymal progenitor cells with robust osteogenic calcification potential. The American Journal of Pathology. 174: 1109-19. PMID 19218344 DOI: 10.2353/Ajpath.2009.080750 |
0.609 |
|
| 2009 |
Zhao R, Wyss K, Simmons CA. Comparison of three material models to predict the time-dependent deformation of a single cell under micropipette aspiration Proceedings of the Asme Summer Bioengineering Conference, Sbc2008. 1051-1052. |
0.478 |
|
| 2008 |
Butcher JT, Simmons CA, Warnock JN. Mechanobiology of the aortic heart valve. The Journal of Heart Valve Disease. 17: 62-73. PMID 18365571 |
0.305 |
|
| 2008 |
Spiteri CG, Young EW, Simmons CA, Kandel RA, Pilliar RM. Substrate architecture and fluid-induced shear stress during chondrocyte seeding: role of alpha5beta1 integrin. Biomaterials. 29: 2477-89. PMID 18314188 DOI: 10.1016/J.Biomaterials.2008.01.018 |
0.364 |
|
| 2008 |
Pho M, Lee W, Watt DR, Laschinger C, Simmons CA, McCulloch CA. Cofilin is a marker of myofibroblast differentiation in cells from porcine aortic cardiac valves American Journal of Physiology - Heart and Circulatory Physiology. 294. PMID 18263709 DOI: 10.1152/Ajpheart.01305.2007 |
0.421 |
|
| 2007 |
Young EW, Wheeler AR, Simmons CA. Matrix-dependent adhesion of vascular and valvular endothelial cells in microfluidic channels. Lab On a Chip. 7: 1759-66. PMID 18030398 DOI: 10.1039/B712486D |
0.372 |
|
| 2007 |
Chong SA, Lee W, Arora PD, Laschinger C, Young EW, Simmons CA, Manolson M, Sodek J, McCulloch CA. Methylglyoxal inhibits the binding step of collagen phagocytosis. The Journal of Biological Chemistry. 282: 8510-20. PMID 17229729 DOI: 10.1074/Jbc.M609859200 |
0.303 |
|
| 2006 |
Young EW, Wheeler A, Simmons CA. A127. Design of an in vitro microfluidic cell culture system to study aortic valve endothelial cells under shear stress Journal of Molecular and Cellular Cardiology. 40: 901. DOI: 10.1016/J.Yjmcc.2006.03.389 |
0.36 |
|
| 2006 |
Ho AS, Yip CY, Simmons CA. A50. Spatial transcriptional profiling of aortic valve interstitial cells Journal of Molecular and Cellular Cardiology. 40: 901. DOI: 10.1016/J.Yjmcc.2006.03.388 |
0.331 |
|
| 2005 |
Simmons CA, Grant GR, Manduchi E, Davies PF. Spatial heterogeneity of endothelial phenotypes correlates with side-specific vulnerability to calcification in normal porcine aortic valves. Circulation Research. 96: 792-9. PMID 15761200 DOI: 10.1161/01.Res.0000161998.92009.64 |
0.359 |
|
| 2005 |
Murphy WL, Hsiong S, Richardson TP, Simmons CA, Mooney DJ. Effects of a bone-like mineral film on phenotype of adult human mesenchymal stem cells in vitro. Biomaterials. 26: 303-10. PMID 15262472 DOI: 10.1016/J.Biomaterials.2004.02.034 |
0.334 |
|
| 2004 |
Simmons CA, Zilberberg J, Davies PF. A rapid, reliable method to isolate high quality endothelial RNA from small spatially-defined locations. Annals of Biomedical Engineering. 32: 1453-9. PMID 15535062 DOI: 10.1114/B:Abme.0000042360.57960.2B |
0.328 |
|
| 2004 |
Simmons CA, Nikolovski J, Thornton AJ, Matlis S, Mooney DJ. Mechanical stimulation and mitogen-activated protein kinase signaling independently regulate osteogenic differentiation and mineralization by calcifying vascular cells. Journal of Biomechanics. 37: 1531-41. PMID 15336928 DOI: 10.1016/J.Jbiomech.2004.01.006 |
0.353 |
|
| 2004 |
Davies PF, Passerini AG, Simmons CA. Aortic valve: turning over a new leaf(let) in endothelial phenotypic heterogeneity. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 1331-3. PMID 15297285 DOI: 10.1161/01.Atv.0000130659.89433.C1 |
0.4 |
|
| 2004 |
Simmons CA, Zilberberg J, Francesco NM, Shi C, Riley R, Davies PF. TRANSCRIPTIONAL PROFILES OF ENDOTHELIUM FROM OPPOSITE SIDES OF THE AORTIC VALVE SUGGEST A LINK BETWEEN HEMODYNAMICS AND VALVULAR CALCIFICATION Cardiovascular Pathology. 13: 186. DOI: 10.1016/J.Carpath.2004.03.561 |
0.34 |
|
| 2003 |
Simmons CA, Matlis S, Thornton AJ, Chen S, Wang CY, Mooney DJ. Cyclic strain enhances matrix mineralization by adult human mesenchymal stem cells via the extracellular signal-regulated kinase (ERK1/2) signaling pathway. Journal of Biomechanics. 36: 1087-96. PMID 12831733 DOI: 10.1016/S0021-9290(03)00110-6 |
0.343 |
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