Josee Dupuis - Publications

Affiliations: 
Boston University, Boston, MA, United States 
Area:
Biostatistics Biology

164 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Bis JC, Jian X, Kunkle BW, Chen Y, Hamilton-Nelson KL, Bush WS, Salerno WJ, Lancour D, Ma Y, Renton AE, Marcora E, Farrell JJ, Zhao Y, Qu L, Ahmad S, ... ... Dupuis J, et al. Correction: Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation. Molecular Psychiatry. PMID 31636380 DOI: 10.1038/s41380-019-0529-7  0.56
2019 Sarnowski C, Leong A, Raffield LM, Wu P, de Vries PS, DiCorpo D, Guo X, Xu H, Liu Y, Zheng X, Hu Y, Brody JA, Goodarzi MO, Hidalgo BA, Highland HM, ... ... Dupuis J, et al. Impact of Rare and Common Genetic Variants on Diabetes Diagnosis by Hemoglobin A1c in Multi-Ancestry Cohorts: The Trans-Omics for Precision Medicine Program. American Journal of Human Genetics. PMID 31564435 DOI: 10.1016/j.ajhg.2019.08.010  0.56
2019 Cardona A, Day FR, Perry JRB, Loh M, Chu AY, Lehne B, Paul DS, Lotta LA, Stewart ID, Kerrison ND, Scott RA, Khaw KT, Forouhi NG, Langenberg C, Liu C, ... ... Dupuis J, et al. Epigenome-Wide Association Study of Incident Type 2 Diabetes in a British Population: EPIC-Norfolk Study. Diabetes. PMID 31506343 DOI: 10.2337/db18-0290  0.56
2019 Murphy AM, Smith CE, Murphy LM, Follis JL, Tanaka T, Richardson K, Noordam R, Lemaitre RN, Kähönen M, Dupuis J, Voortman T, Marouli E, Mook-Kanamori DO, Raitakari OT, Hong J, et al. Potential Interplay Between Dietary Saturated Fats and Genetic Variants of the NLRP3 Inflammasome, to Modulate Insulin Resistance and Diabetes Risk: insights from a Meta-Analysis of 19,005 Individuals. Molecular Nutrition & Food Research. e1900226. PMID 31432628 DOI: 10.1002/mnfr.201900226  0.4
2019 Liu CT, Merino J, Rybin D, DiCorpo D, Benke KS, Bragg-Gresham JL, Canouil M, Corre T, Grallert H, Isaacs A, Kutalik Z, Lahti J, Marullo L, Marzi C, Rasmussen-Torvik LJ, ... ... Dupuis J, et al. Genome-wide Association Study of Change in Fasting Glucose over time in 13,807 non-diabetic European Ancestry Individuals. Scientific Reports. 9: 9439. PMID 31263163 DOI: 10.1038/s41598-019-45823-7  0.4
2019 Liu J, Carnero-Montoro E, van Dongen J, Lent S, Nedeljkovic I, Ligthart S, Tsai PC, Martin TC, Mandaviya PR, Jansen R, Peters MJ, Duijts L, Jaddoe VWV, Tiemeier H, Felix JF, ... ... Dupuis J, et al. An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis. Nature Communications. 10: 2581. PMID 31197173 DOI: 10.1038/s41467-019-10487-4  0.48
2019 Flannick J, Mercader JM, Fuchsberger C, Udler MS, Mahajan A, Wessel J, Teslovich TM, Caulkins L, Koesterer R, Barajas-Olmos F, Blackwell TW, Boerwinkle E, Brody JA, Centeno-Cruz F, Chen L, ... ... Dupuis J, et al. Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls. Nature. PMID 31118516 DOI: 10.1038/s41586-019-1231-2  0.48
2019 Chung J, Jun GR, Dupuis J, Farrer LA. Comparison of methods for multivariate gene-based association tests for complex diseases using common variants. European Journal of Human Genetics : Ejhg. PMID 30683923 DOI: 10.1038/s41431-018-0327-8  0.32
2019 Leong A, Chen J, Wheeler E, Hivert MF, Liu CT, Merino J, Dupuis J, Tai ES, Rotter JI, Florez JC, Barroso I, Meigs JB. Mendelian Randomization Analysis of Hemoglobin A as a Risk Factor for Coronary Artery Disease. Diabetes Care. PMID 30659074 DOI: 10.2337/dc18-1712  0.4
2018 Hendricks AE, Billups SC, Pike HNC, Farooqi IS, Zeggini E, Santorico SA, Barroso I, Dupuis J. ProxECAT: Proxy External Controls Association Test. A new case-control gene region association test using allele frequencies from public controls. Plos Genetics. 14: e1007591. PMID 30325923 DOI: 10.1371/journal.pgen.1007591  0.4
2018 Mahajan A, Taliun D, Thurner M, Robertson NR, Torres JM, Rayner NW, Payne AJ, Steinthorsdottir V, Scott RA, Grarup N, Cook JP, Schmidt EM, Wuttke M, Sarnowski C, Mägi R, ... ... Dupuis J, et al. Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps. Nature Genetics. PMID 30297969 DOI: 10.1038/s41588-018-0241-6  0.48
2018 Bis JC, Jian X, Kunkle BW, Chen Y, Hamilton-Nelson KL, Bush WS, Salerno WJ, Lancour D, Ma Y, Renton AE, Marcora E, Farrell JJ, Zhao Y, Qu L, Ahmad S, ... ... Dupuis J, et al. Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation. Molecular Psychiatry. PMID 30108311 DOI: 10.1038/s41380-018-0112-7  0.56
2018 Merino J, Dashti HS, Li SX, Sarnowski C, Justice AE, Graff M, Papoutsakis C, Smith CE, Dedoussis GV, Lemaitre RN, Wojczynski MK, Männistö S, Ngwa JS, Kho M, Ahluwalia TS, ... ... Dupuis J, et al. Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium. Molecular Psychiatry. PMID 29988085 DOI: 10.1038/s41380-018-0079-4  0.56
2018 Naj AC, Lin H, Vardarajan BN, White S, Lancour D, Ma Y, Schmidt M, Sun F, Butkiewicz M, Bush WS, Kunkle BW, Malamon J, Amin N, Choi SH, Hamilton-Nelson KL, ... ... Dupuis J, et al. Quality control and integration of genotypes from two calling pipelines for whole genome sequence data in the Alzheimer's disease sequencing project. Genomics. PMID 29857119 DOI: 10.1016/j.ygeno.2018.05.004  0.32
2018 Mendelson MM, Johannes R, Liu C, Huan T, Yao C, Miao X, Murabito JM, Dupuis J, Levy D, Benjamin EJ, Lin H. Epigenome-Wide Association Study of Soluble Tumor Necrosis Factor Receptor 2 Levels in the Framingham Heart Study. Frontiers in Pharmacology. 9: 207. PMID 29740313 DOI: 10.3389/fphar.2018.00207  0.56
2018 Vassy JL, Hivert MF, Porneala B, Dauriz M, Florez JC, Dupuis J, Siscovick DS, Fornage M, Rasmussen-Torvik LJ, Bouchard C, Meigs JB. Erratum. Polygenic Type 2 Diabetes Prediction at the Limit of Common Variant Detection. Diabetes 2014;63:2172-2182. Diabetes. PMID 29669744 DOI: 10.2337/db18-er06a  0.32
2018 Mahajan A, Wessel J, Willems SM, Zhao W, Robertson NR, Chu AY, Gan W, Kitajima H, Taliun D, Rayner NW, Guo X, Lu Y, Li M, Jensen RA, Hu Y, ... ... Dupuis J, et al. Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes. Nature Genetics. 50: 559-571. PMID 29632382 DOI: 10.1038/s41588-018-0084-1  0.48
2018 Merino J, Leong A, Liu CT, Porneala B, Walford GA, von Grotthuss M, Wang TJ, Flannick J, Dupuis J, Levy D, Gerszten RE, Florez JC, Meigs JB. Metabolomics insights into early type 2 diabetes pathogenesis and detection in individuals with normal fasting glucose. Diabetologia. PMID 29626220 DOI: 10.1007/s00125-018-4599-x  0.48
2018 Blue EE, Bis JC, Dorschner MO, Tsuang DW, Barral SM, Beecham G, Below JE, Bush WS, Butkiewicz M, Cruchaga C, DeStefano A, Farrer LA, Goate A, Haines J, Jaworski J, ... ... Dupuis J, et al. Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project. Dementia and Geriatric Cognitive Disorders. 45: 1-17. PMID 29486463 DOI: 10.1159/000485503  0.32
2018 Flannick J, Fuchsberger C, Mahajan A, Teslovich TM, Agarwala V, Gaulton KJ, Caulkins L, Koesterer R, Ma C, Moutsianas L, McCarthy DJ, Rivas MA, Perry JRB, Sim X, Blackwell TW, ... ... Dupuis J, et al. Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. Scientific Data. 5: 180002. PMID 29360107 DOI: 10.1038/sdata.2018.2  0.4
2018 Jiang X, O'Reilly PF, Aschard H, Hsu YH, Richards JB, Dupuis J, Ingelsson E, Karasik D, Pilz S, Berry D, Kestenbaum B, Zheng J, Luan J, Sofianopoulou E, Streeten EA, et al. Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels. Nature Communications. 9: 260. PMID 29343764 DOI: 10.1038/s41467-017-02662-2  0.56
2018 Hong J, Hatchell KE, Bradfield JP, Andrew B, Alessandra C, Chao-Qiang L, Langefeld CD, Lu L, Lu Y, Lutsey PL, Musani SK, Nalls MA, Robinson-Cohen C, Roizen JD, Saxena R, ... ... Dupuis J, et al. Trans-ethnic Evaluation Identifies Novel Low Frequency Loci Associated with 25-Hydroxyvitamin D Concentrations. The Journal of Clinical Endocrinology and Metabolism. PMID 29325163 DOI: 10.1210/jc.2017-01802  0.48
2017 Sarnowski C, Satizabal CL, DeCarli C, Pitsillides AN, Cupples LA, Vasan RS, Wilson JG, Bis JC, Fornage M, Beiser AS, DeStefano AL, Dupuis J, Seshadri S. Whole genome sequence analyses of brain imaging measures in the Framingham Study. Neurology. PMID 29282330 DOI: 10.1212/WNL.0000000000004820  0.56
2017 Jun G, Manning A, Almeida M, Zawistowski M, Wood AR, Teslovich TM, Fuchsberger C, Feng S, Cingolani P, Gaulton KJ, Dyer T, Blackwell TW, Chen H, Chines PS, Choi S, ... ... Dupuis J, et al. Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees. Proceedings of the National Academy of Sciences of the United States of America. PMID 29279374 DOI: 10.1073/pnas.1705859115  0.4
2017 Jason F, Fuchsberger C, Mahajan A, Teslovich TM, Agarwala V, Gaulton KJ, Caulkins L, Koesterer R, Ma C, Moutsianas L, McCarthy DJ, Rivas MA, Perry JRB, Sim X, Blackwell TW, ... ... Dupuis J, et al. Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. Scientific Data. 4: 170179. PMID 29257133 DOI: 10.1038/sdata.2017.179  0.4
2017 Weng LC, Choi SH, Klarin D, Smith JG, Loh PR, Chaffin M, Roselli C, Hulme OL, Lunetta KL, Dupuis J, Benjamin EJ, Newton-Cheh C, Kathiresan S, Ellinor PT, Lubitz SA. Heritability of Atrial Fibrillation. Circulation. Cardiovascular Genetics. 10. PMID 29237688 DOI: 10.1161/CIRCGENETICS.117.001838  0.32
2017 McKeown NM, Dashti HS, Ma J, Haslam DE, Kiefte-de Jong JC, Smith CE, Tanaka T, Graff M, Lemaitre RN, Rybin D, Sonestedt E, Frazier-Wood AC, Mook-Kanamori DO, Li Y, Wang CA, ... ... Dupuis J, et al. Sugar-sweetened beverage intake associations with fasting glucose and insulin concentrations are not modified by selected genetic variants in a ChREBP-FGF21 pathway: a meta-analysis. Diabetologia. PMID 29098321 DOI: 10.1007/s00125-017-4475-0  0.56
2017 Strawbridge RJ, Silveira A, Hoed MD, Gustafsson S, Luan J, Rybin D, Dupuis J, Li-Gao R, Kavousi M, Dehghan A, Haljas K, Lahti J, Gådin JR, Bäcklund A, de Faire U, et al. Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomisation. Atherosclerosis. 266: 196-204. PMID 29040868 DOI: 10.1016/j.atherosclerosis.2017.09.031  0.32
2017 Willinger CM, Rong J, Tanriverdi K, Courchesne PL, Huan T, Wasserman GA, Lin H, Dupuis J, Joehanes R, Jones MR, Chen G, Benjamin EJ, O'Connor GT, Mizgerd JP, Freedman JE, et al. MicroRNA Signature of Cigarette Smoking and Evidence for a Putative Causal Role of MicroRNAs in Smoking-Related Inflammation and Target Organ Damage. Circulation. Cardiovascular Genetics. 10. PMID 29030400 DOI: 10.1161/CIRCGENETICS.116.001678  0.48
2017 Wheeler E, Leong A, Liu CT, Hivert MF, Strawbridge RJ, Podmore C, Li M, Yao J, Sim X, Hong J, Chu AY, Zhang W, Wang X, Chen P, Maruthur NM, ... ... Dupuis J, et al. Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis. Plos Medicine. 14: e1002383. PMID 28898252 DOI: 10.1371/journal.pmed.1002383  0.48
2017 Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, ... ... Dupuis J, et al. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nature Genetics. PMID 28714976 DOI: 10.1038/ng.3916  0.32
2017 Scott RA, Scott LJ, Mägi R, Marullo L, Gaulton KJ, Kaakinen M, Pervjakova N, Pers TH, Johnson AD, Eicher JD, Jackson AU, Ferreira T, Lee Y, Ma C, Steinthorsdottir V, ... ... Dupuis J, et al. An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans. Diabetes. PMID 28566273 DOI: 10.2337/db16-1253  0.48
2017 Manning A, Highland HM, Gasser J, Sim X, Tukiainen T, Fontanillas P, Grarup N, Rivas MA, Mahajan A, Locke AE, Cingolani P, Pers TH, Viñuela A, Brown AA, Wu Y, ... ... Dupuis J, et al. A Low-Frequency Inactivating Akt2 Variant Enriched in the Finnish Population is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk. Diabetes. PMID 28341696 DOI: 10.2337/db16-1329  0.32
2017 Merino J, Leong A, Posner DC, Porneala B, Masana L, Dupuis J, Florez JC. Genetically Driven Hyperglycemia Increases Risk of Coronary Artery Disease Separately From Type 2 Diabetes. Diabetes Care. PMID 28298470 DOI: 10.2337/dc16-2625  0.32
2017 Choi SH, Labadorf AT, Myers RH, Lunetta KL, Dupuis J, DeStefano AL. Evaluation of logistic regression models and effect of covariates for case-control study in RNA-Seq analysis. Bmc Bioinformatics. 18: 91. PMID 28166718 DOI: 10.1186/s12859-017-1498-y  0.32
2017 Joehanes R, Zhang X, Huan T, Yao C, Ying SX, Nguyen QT, Demirkale CY, Feolo ML, Sharopova NR, Sturcke A, Schäffer AA, Heard-Costa N, Chen H, Liu PC, Wang R, ... ... Dupuis J, et al. Integrated genome-wide analysis of expression quantitative trait loci aids interpretation of genomic association studies. Genome Biology. 18: 16. PMID 28122634 DOI: 10.1186/s13059-016-1142-6  0.48
2016 Ligthart S, Marzi C, Aslibekyan S, Mendelson MM, Conneely KN, Tanaka T, Colicino E, Waite LL, Joehanes R, Guan W, Brody JA, Elks C, Marioni R, Jhun MA, Agha G, ... ... Dupuis J, et al. DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases. Genome Biology. 17: 255. PMID 27955697 DOI: 10.1186/s13059-016-1119-5  0.56
2016 Wang S, Meigs JB, Dupuis J. Joint association analysis of a binary and a quantitative trait in family samples. European Journal of Human Genetics : Ejhg. PMID 27782109 DOI: 10.1038/ejhg.2016.134  0.32
2016 Chen BH, Hivert MF, Peters MJ, Pilling LC, Hogan JD, Pham LM, Harries LW, Fox CS, Bandinelli S, Dehghan A, Hernandez DG, Hofman A, Hong J, Joehanes R, Johnson AD, ... ... Dupuis J, et al. Peripheral Blood Transcriptomic Signatures of Fasting Glucose and Insulin Concentrations. Diabetes. PMID 27625022 DOI: 10.2337/db16-0470  0.48
2016 Walford GA, Gustafsson S, Rybin D, Stančáková A, Chen H, Liu CT, Hong J, Jensen RA, Rice K, Morris AP, Mägi R, Tönjes A, Prokopenko I, Kleber ME, Delgado G, ... ... Dupuis J, et al. Genome-wide association study of the modified Stumvoll Insulin Sensitivity Index identifies BCL2 and FAM19A2 as novel insulin sensitivity loci. Diabetes. PMID 27416945 DOI: 10.2337/db16-0199  0.4
2016 Fuchsberger C, Flannick J, Teslovich TM, Mahajan A, Agarwala V, Gaulton KJ, Ma C, Fontanillas P, Moutsianas L, McCarthy DJ, Rivas MA, Perry JR, Sim X, Blackwell TW, Robertson NR, ... ... Dupuis J, et al. The genetic architecture of type 2 diabetes. Nature. PMID 27398621 DOI: 10.1038/nature18642  0.72
2016 Liu CT, Raghavan S, Maruthur N, Kabagambe EK, Hong J, Ng MC, Hivert MF, Lu Y, An P, Bentley AR, Drolet AM, Gaulton KJ, Guo X, Armstrong LL, Irvin MR, ... ... Dupuis J, et al. Trans-ethnic Meta-Analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin. American Journal of Human Genetics. PMID 27321945 DOI: 10.1016/j.ajhg.2016.05.006  0.4
2016 Scott RA, Freitag DF, Li L, Chu AY, Surendran P, Young R, Grarup N, Stancáková A, Chen Y, Varga TV, Yaghootkar H, Luan J, Zhao JH, Willems SM, Wessel J, ... ... Dupuis J, et al. A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease. Science Translational Medicine. 8: 341ra76. PMID 27252175 DOI: 10.1126/scitranslmed.aad3744  0.56
2016 Xing C, M McCarthy J, Dupuis J, Adrienne Cupples L, B Meigs J, Lin X, S Allen A. Robust analysis of secondary phenotypes in case-control genetic association studies. Statistics in Medicine. PMID 27241694 DOI: 10.1002/sim.6976  0.32
2016 Raghavan S, Pachucki MC, Chang Y, Porneala B, Fox CS, Dupuis J, Meigs JB. Incident Type 2 Diabetes Risk is Influenced by Obesity and Diabetes in Social Contacts: a Social Network Analysis. Journal of General Internal Medicine. PMID 27145760 DOI: 10.1007/s11606-016-3723-1  0.72
2016 Hong J, Lunetta KL, Cupples LA, Dupuis J, Liu CT. Evaluation of a Two-Stage Approach in Trans-Ethnic Meta-Analysis in Genome-Wide Association Studies. Genetic Epidemiology. PMID 27061095 DOI: 10.1002/gepi.21963  0.72
2016 Wang S, Zhao JH, An P, Guo X, Jensen RA, Marten J, Huffman JE, Meidtner K, Boeing H, Campbell A, Rice KM, Scott RA, Yao J, Schulze MB, Wareham NJ, ... ... Dupuis J, et al. General Framework for Meta-Analysis of Haplotype Association Tests. Genetic Epidemiology. 40: 244-252. PMID 27027517 DOI: 10.1002/gepi.21959  0.72
2016 Horikoshi M, Pasquali L, Wiltshire S, Huyghe JR, Mahajan A, Asimit JL, Ferreira T, Locke AE, Robertson NR, Wang X, Sim X, Fujita H, Hara K, Young R, Zhang W, ... ... Dupuis J, et al. Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms. Human Molecular Genetics. PMID 26911676 DOI: 10.1093/hmg/ddw048  0.4
2016 Leong A, Porneala B, Dupuis J, Florez JC, Meigs JB. Type 2 Diabetes Genetic Predisposition, Obesity, and All-Cause Mortality Risk in the U.S.: A Multiethnic Analysis. Diabetes Care. PMID 26884474 DOI: 10.2337/dc15-2080  0.32
2016 Willems SM, Cornes BK, Brody JA, Morrison AC, Lipovich L, Dauriz M, Chen Y, Liu CT, Rybin DV, Gibbs RA, Muzny D, Pankow JS, Psaty BM, Boerwinkle E, Rotter JI, ... ... Dupuis J, et al. Association of the IGF1 gene with fasting insulin levels. European Journal of Human Genetics : Ejhg. PMID 26860063 DOI: 10.1038/ejhg.2016.4  0.4
2016 Ho JE, Gao W, Levy D, Santhanakrishnan R, Araki T, Rosas IO, Hatabu H, Latourelle JC, Nishino M, Dupuis J, Washko GR, O'Connor GT, Hunninghake GM. Galectin-3 is Associated with Restrictive Lung Disease and Interstitial Lung Abnormalities. American Journal of Respiratory and Critical Care Medicine. PMID 26771117 DOI: 10.1164/rccm.201509-1753OC  0.72
2016 Kan M, Auer PL, Wang GT, Bucasas KL, Hooker S, Rodriguez A, Li B, Ellis J, Adrienne Cupples L, Ida Chen YD, Dupuis J, Fox CS, Gross MD, Smith JD, Heard-Costa N, et al. Rare variant associations with waist-to-hip ratio in European-American and African-American women from the NHLBI-Exome Sequencing Project. European Journal of Human Genetics : Ejhg. PMID 26757982 DOI: 10.1038/ejhg.2015.272  0.32
2015 Sitlani CM, Dupuis J, Rice KM, Sun F, Pitsillides AN, Cupples LA, Psaty BM. Genome-wide gene-environment interactions on quantitative traits using family data. European Journal of Human Genetics : Ejhg. PMID 26626313 DOI: 10.1038/ejhg.2015.253  0.56
2015 Xing C, Huang J, Hsu YH, DeStefano AL, Heard-Costa NL, Wolf PA, Seshadri S, Kiel DP, Cupples LA, Dupuis J. Evaluation of power of the Illumina HumanOmni5M-4v1 BeadChip to detect risk variants for human complex diseases. European Journal of Human Genetics : Ejhg. PMID 26577045 DOI: 10.1038/ejhg.2015.244  0.72
2015 Kliment CR, Araki T, Doyle TJ, Gao W, Dupuis J, Latourelle JC, Zazueta OE, Fernandez IE, Nishino M, Okajima Y, Ross JC, Estépar RS, Diaz AA, Lederer DJ, Schwartz DA, et al. A comparison of visual and quantitative methods to identify interstitial lung abnormalities. Bmc Pulmonary Medicine. 15: 134. PMID 26514822 DOI: 10.1186/s12890-015-0124-x  0.72
2015 Hochner H, Allard C, Granot-Hershkovitz E, Chen J, Sitlani CM, Sazdovska S, Lumley T, McKnight B, Rice K, Enquobahrie DA, Meigs JB, Kwok P, Hivert MF, Borecki IB, Gomez F, ... ... Dupuis J, et al. Parent-of-Origin Effects of the APOB Gene on Adiposity in Young Adults. Plos Genetics. 11: e1005573. PMID 26451733 DOI: 10.1371/journal.pgen.1005573  0.32
2015 Pilling LC, Joehanes R, Melzer D, Harries LW, Henley W, Dupuis J, Lin H, Mitchell M, Hernandez D, Ying SX, Lunetta KL, Benjamin EJ, Singleton A, Levy D, Munson P, et al. Gene expression markers of age-related inflammation in two human cohorts. Experimental Gerontology. PMID 26087330 DOI: 10.1016/j.exger.2015.05.012  0.48
2015 Dauriz M, Porneala BC, Guo X, Bielak LF, Peyser PA, Durant NH, Carnethon MR, Bonadonna RC, Bonora E, Bowden DW, Florez JC, Fornage M, Hivert MF, Jacobs DR, Kabagambe EK, ... ... Dupuis J, et al. Association of a 62 Variants Type 2 Diabetes Genetic Risk Score With Markers of Subclinical Atherosclerosis: A Transethnic, Multicenter Study. Circulation. Cardiovascular Genetics. 8: 507-15. PMID 25805414 DOI: 10.1161/CIRCGENETICS.114.000740  0.32
2015 Mahajan A, Sim X, Ng HJ, Manning A, Rivas MA, Highland HM, Locke AE, Grarup N, Im HK, Cingolani P, Flannick J, Fontanillas P, Fuchsberger C, Gaulton KJ, Teslovich TM, ... ... Dupuis J, et al. Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus. Plos Genetics. 11: e1004876. PMID 25625282 DOI: 10.1371/journal.pgen.1004876  0.72
2015 Raghavan S, Porneala B, McKeown N, Fox CS, Dupuis J, Meigs JB. Metabolic factors and genetic risk mediate familial type 2 diabetes risk in the Framingham Heart Study. Diabetologia. 58: 988-96. PMID 25619168 DOI: 10.1007/s00125-015-3498-7  0.32
2015 Liu C, Dupuis J, Larson MG, Cupples LA, Ordovas JM, Vasan RS, Meigs JB, Jacques PF, Levy D. Revisiting heritability accounting for shared environmental effects and maternal inheritance. Human Genetics. 134: 169-79. PMID 25381465 DOI: 10.1007/s00439-014-1505-6  0.72
2015 Chen H, Dupuis J. Rare variant association analysis: Beyond collapsing approaches Assessing Rare Variation in Complex Traits: Design and Analysis of Genetic Studies. 149-167. DOI: 10.1007/978-1-4939-2824-8_11  0.72
2014 Chen H, Choi SH, Hong J, Lu C, Milton JN, Allard C, Lacey SM, Lin H, Dupuis J. Rare genetic variant analysis on blood pressure in related samples. Bmc Proceedings. 8: S35. PMID 25519320 DOI: 10.1186/1753-6561-8-S1-S35  0.4
2014 Lin H, Joehanes R, Pilling LC, Dupuis J, Lunetta KL, Ying SX, Benjamin EJ, Hernandez D, Singleton A, Melzer D, Munson PJ, Levy D, Ferrucci L, Murabito JM. Whole blood gene expression and interleukin-6 levels. Genomics. 104: 490-5. PMID 25311648 DOI: 10.1016/j.ygeno.2014.10.003  0.72
2014 Xing C, Dupuis J, Cupples LA. Performance of statistical methods on CHARGE targeted sequencing data. Bmc Genetics. 15: 104. PMID 25277365 DOI: 10.1186/s12863-014-0104-9  0.56
2014 Kwan JS, Hsu YH, Cheung CL, Dupuis J, Saint-Pierre A, Eriksson J, Handelman SK, Aragaki A, Karasik D, Pramstaller PP, Kooperberg C, Lacroix AZ, Larson MG, Lau KS, Lorentzon M, et al. Meta-analysis of genome-wide association studies identifies two loci associated with circulating osteoprotegerin levels. Human Molecular Genetics. 23: 6684-93. PMID 25080503 DOI: 10.1093/hmg/ddu386  0.48
2014 Chen H, Meigs JB, Dupuis J. Incorporating gene-environment interaction in testing for association with rare genetic variants. Human Heredity. 78: 81-90. PMID 25060534 DOI: 10.1159/000363347  0.72
2014 Tang W, Kowgier M, Loth DW, Soler Artigas M, Joubert BR, Hodge E, Gharib SA, Smith AV, Ruczinski I, Gudnason V, Mathias RA, Harris TB, Hansel NN, Launer LJ, Barnes KC, ... ... Dupuis J, et al. Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function. Plos One. 9: e100776. PMID 24983941 DOI: 10.1371/journal.pone.0100776  0.72
2014 Kraja AT, Chasman DI, North KE, Reiner AP, Yanek LR, Kilpeläinen TO, Smith JA, Dehghan A, Dupuis J, Johnson AD, Feitosa MF, Tekola-Ayele F, Chu AY, Nolte IM, Dastani Z, et al. Pleiotropic genes for metabolic syndrome and inflammation. Molecular Genetics and Metabolism. 112: 317-38. PMID 24981077 DOI: 10.1016/j.ymgme.2014.04.007  0.72
2014 Vimaleswaran KS, Cavadino A, Berry DJ, Jorde R, Dieffenbach AK, Lu C, Alves AC, Heerspink HJ, Tikkanen E, Eriksson J, Wong A, Mangino M, Jablonski KA, Nolte IM, ... ... Dupuis J, et al. Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study. The Lancet. Diabetes & Endocrinology. 2: 719-29. PMID 24974252 DOI: 10.1016/S2213-8587(14)70113-5  0.72
2014 Cornes BK, Brody JA, Nikpoor N, Morrison AC, Dang HC, Ahn BS, Wang S, Dauriz M, Barzilay JI, Dupuis J, Florez JC, Coresh J, Gibbs RA, Kao WH, Liu CT, et al. Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. Circulation. Cardiovascular Genetics. 7: 374-82. PMID 24951664 DOI: 10.1161/CIRCGENETICS.113.000169  0.72
2014 Lin H, Wang M, Brody JA, Bis JC, Dupuis J, Lumley T, McKnight B, Rice KM, Sitlani CM, Reid JG, Bressler J, Liu X, Davis BC, Johnson AD, O'Donnell CJ, et al. Strategies to design and analyze targeted sequencing data: cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. Circulation. Cardiovascular Genetics. 7: 335-43. PMID 24951659 DOI: 10.1161/CIRCGENETICS.113.000350  0.72
2014 Lin H, Yin X, Lunetta KL, Dupuis J, McManus DD, Lubitz SA, Magnani JW, Joehanes R, Munson PJ, Larson MG, Levy D, Ellinor PT, Benjamin EJ. Whole blood gene expression and atrial fibrillation: the Framingham Heart Study. Plos One. 9: e96794. PMID 24805109 DOI: 10.1371/journal.pone.0096794  0.72
2014 Ellis J, Lange EM, Li J, Dupuis J, Baumert J, Walston JD, Keating BJ, Durda P, Fox ER, Palmer CD, Meng YA, Young T, Farlow DN, Schnabel RB, Marzi CS, et al. Large multiethnic Candidate Gene Study for C-reactive protein levels: identification of a novel association at CD36 in African Americans. Human Genetics. 133: 985-95. PMID 24643644 DOI: 10.1007/s00439-014-1439-z  0.72
2014 Vassy JL, Hivert MF, Porneala B, Dauriz M, Florez JC, Dupuis J, Siscovick DS, Fornage M, Rasmussen-Torvik LJ, Bouchard C, Meigs JB. Polygenic type 2 diabetes prediction at the limit of common variant detection. Diabetes. 63: 2172-82. PMID 24520119 DOI: 10.2337/db13-1663  0.72
2014 Mahajan A, Go MJ, Zhang W, Below JE, Gaulton KJ, Ferreira T, Horikoshi M, Johnson AD, Ng MC, Prokopenko I, ... ... Dupuis J, et al. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nature Genetics. 46: 234-44. PMID 24509480 DOI: 10.1038/ng.2897  0.72
2014 Chen H, Lumley T, Brody J, Heard-Costa NL, Fox CS, Cupples LA, Dupuis J. Sequence kernel association test for survival traits. Genetic Epidemiology. 38: 191-7. PMID 24464521 DOI: 10.1002/gepi.21791  0.72
2014 Manichaikul A, Hoffman EA, Smolonska J, Gao W, Cho MH, Baumhauer H, Budoff M, Austin JH, Washko GR, Carr JJ, Kaufman JD, Pottinger T, Powell CA, Wijmenga C, Zanen P, ... ... Dupuis J, et al. Genome-wide study of percent emphysema on computed tomography in the general population. The Multi-Ethnic Study of Atherosclerosis Lung/SNP Health Association Resource Study. American Journal of Respiratory and Critical Care Medicine. 189: 408-18. PMID 24383474 DOI: 10.1164/rccm.201306-1061OC  0.72
2014 Dimas AS, Lagou V, Barker A, Knowles JW, Mägi R, Hivert MF, Benazzo A, Rybin D, Jackson AU, Stringham HM, Song C, Fischer-Rosinsky A, Boesgaard TW, Grarup N, Abbasi FA, ... ... Dupuis J, et al. Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity. Diabetes. 63: 2158-71. PMID 24296717 DOI: 10.2337/db13-0949  0.72
2014 Hendricks AE, Dupuis J, Logue MW, Myers RH, Lunetta KL. Correction for multiple testing in a gene region. European Journal of Human Genetics : Ejhg. 22: 414-8. PMID 23838599 DOI: 10.1038/ejhg.2013.144  0.72
2013 Yaghootkar H, Lamina C, Scott RA, Dastani Z, Hivert MF, Warren LL, Stancáková A, Buxbaum SG, Lyytikäinen LP, Henneman P, Wu Y, Cheung CY, Pankow JS, Jackson AU, Gustafsson S, ... ... Dupuis J, et al. Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes. Diabetes. 62: 3589-98. PMID 23835345 DOI: 10.2337/db13-0128  0.72
2013 Hunninghake GM, Hatabu H, Okajima Y, Gao W, Dupuis J, Latourelle JC, Nishino M, Araki T, Zazueta OE, Kurugol S, Ross JC, San José Estépar R, Murphy E, Steele MP, Loyd JE, et al. MUC5B promoter polymorphism and interstitial lung abnormalities. The New England Journal of Medicine. 368: 2192-200. PMID 23692170 DOI: 10.1056/NEJMoa1216076  0.72
2013 Lim S, Hong J, Liu CT, Hivert MF, White CC, Murabito JM, O'Donnell CJ, Dupuis J, Florez JC, Meigs JB. Common variants in and near IRS1 and subclinical cardiovascular disease in the Framingham Heart Study. Atherosclerosis. 229: 149-54. PMID 23659870 DOI: 10.1016/j.atherosclerosis.2013.03.037  0.72
2013 Reiner AP, Hartiala J, Zeller T, Bis JC, Dupuis J, Fornage M, Baumert J, Kleber ME, Wild PS, Baldus S, Bielinski SJ, Fontes JD, Illig T, Keating BJ, Lange LA, et al. Genome-wide and gene-centric analyses of circulating myeloperoxidase levels in the charge and care consortia. Human Molecular Genetics. 22: 3381-93. PMID 23620142 DOI: 10.1093/hmg/ddt189  0.72
2013 de Miguel-Yanes JM, Porneala B, Pencina MJ, Fox CS, Florez JC, Siscovick DS, Dupuis J, Meigs JB. Lack of interaction of beta-cell-function-associated variants with hypertension on change in fasting glucose and diabetes risk: the Framingham Offspring Study. Journal of Hypertension. 31: 1001-9. PMID 23425704 DOI: 10.1097/HJH.0b013e32835f5a83  0.72
2013 Vimaleswaran KS, Berry DJ, Lu C, Tikkanen E, Pilz S, Hiraki LT, Cooper JD, Dastani Z, Li R, Houston DK, Wood AR, Michaëlsson K, Vandenput L, Zgaga L, Yerges-Armstrong LM, ... ... Dupuis J, et al. Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts. Plos Medicine. 10: e1001383. PMID 23393431 DOI: 10.1371/journal.pmed.1001383  0.72
2013 Liu C, Dupuis J, Larson MG, Levy D. Association testing of the mitochondrial genome using pedigree data. Genetic Epidemiology. 37: 239-47. PMID 23319385 DOI: 10.1002/gepi.21706  0.72
2013 Chen H, Meigs JB, Dupuis J. Sequence kernel association test for quantitative traits in family samples. Genetic Epidemiology. 37: 196-204. PMID 23280576 DOI: 10.1002/gepi.21703  0.72
2013 Nettleton JA, Hivert MF, Lemaitre RN, McKeown NM, Mozaffarian D, Tanaka T, Wojczynski MK, Hruby A, Djoussé L, Ngwa JS, Follis JL, Dimitriou M, Ganna A, Houston DK, Kanoni S, ... ... Dupuis J, et al. Meta-analysis investigating associations between healthy diet and fasting glucose and insulin levels and modification by loci associated with glucose homeostasis in data from 15 cohorts. American Journal of Epidemiology. 177: 103-15. PMID 23255780 DOI: 10.1093/aje/kws297  0.72
2013 Ng MC, Saxena R, Li J, Palmer ND, Dimitrov L, Xu J, Rasmussen-Torvik LJ, Zmuda JM, Siscovick DS, Patel SR, Crook ED, Sims M, Chen YD, Bertoni AG, Li M, ... ... Dupuis J, et al. Transferability and fine mapping of type 2 diabetes loci in African Americans: the Candidate Gene Association Resource Plus Study. Diabetes. 62: 965-76. PMID 23193183 DOI: 10.2337/db12-0266  0.72
2013 Hansel NN, Ruczinski I, Rafaels N, Sin DD, Daley D, Malinina A, Huang L, Sandford A, Murray T, Kim Y, Vergara C, Heckbert SR, Psaty BM, Li G, Elliott WM, ... ... Dupuis J, et al. Genome-wide study identifies two loci associated with lung function decline in mild to moderate COPD. Human Genetics. 132: 79-90. PMID 22986903 DOI: 10.1007/s00439-012-1219-6  0.72
2013 Dupuis J, Coutu J, Laneuville O. Application of linear mixed-effect models for the analysis of exam scores: Online video associated with higher scores for undergraduate students with lower grades Computers and Education. 66: 64-73. DOI: 10.1016/j.compedu.2013.02.011  0.72
2012 Mercader JM, Puiggros M, Segrè AV, Planet E, Sorianello E, Sebastian D, Rodriguez-Cuenca S, Ribas V, Bonàs-Guarch S, Draghici S, Yang C, Mora S, Vidal-Puig A, Dupuis J, et al. Identification of novel type 2 diabetes candidate genes involved in the crosstalk between the mitochondrial and the insulin signaling systems. Plos Genetics. 8: e1003046. PMID 23236286 DOI: 10.1371/journal.pgen.1003046  0.72
2012 Liu CT, Ng MC, Rybin D, Adeyemo A, Bielinski SJ, Boerwinkle E, Borecki I, Cade B, Chen YD, Djousse L, Fornage M, Goodarzi MO, Grant SF, Guo X, Harris T, ... ... Dupuis J, et al. Transferability and fine-mapping of glucose and insulin quantitative trait loci across populations: CARe, the Candidate Gene Association Resource. Diabetologia. 55: 2970-84. PMID 22893027 DOI: 10.1007/s00125-012-2656-4  0.72
2012 Wilk JB, Shrine NR, Loehr LR, Zhao JH, Manichaikul A, Lopez LM, Smith AV, Heckbert SR, Smolonska J, Tang W, Loth DW, Curjuric I, Hui J, Cho MH, Latourelle JC, ... ... Dupuis J, et al. Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction. American Journal of Respiratory and Critical Care Medicine. 186: 622-32. PMID 22837378 DOI: 10.1164/rccm.201202-0366OC  0.72
2012 Hendricks AE, Dupuis J, Gupta M, Logue MW, Lunetta KL. A comparison of gene region simulation methods. Plos One. 7: e40925. PMID 22815869 DOI: 10.1371/journal.pone.0040925  0.72
2012 Billings LK, Hsu YH, Ackerman RJ, Dupuis J, Voight BF, Rasmussen-Torvik LJ, Hercberg S, Lathrop M, Barnes D, Langenberg C, Hui J, Fu M, Bouatia-Naji N, Lecoeur C, An P, et al. Impact of common variation in bone-related genes on type 2 diabetes and related traits. Diabetes. 61: 2176-86. PMID 22698912 DOI: 10.2337/db11-1515  0.72
2012 Perry JR, Voight BF, Yengo L, Amin N, Dupuis J, Ganser M, Grallert H, Navarro P, Li M, Qi L, Steinthorsdottir V, Scott RA, Almgren P, Arking DE, Aulchenko Y, et al. Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. Plos Genetics. 8: e1002741. PMID 22693455 DOI: 10.1371/journal.pgen.1002741  0.72
2012 Chen H, Manning AK, Dupuis J. A method of moments estimator for random effect multivariate meta-analysis. Biometrics. 68: 1278-84. PMID 22551393 DOI: 10.1111/j.1541-0420.2012.01761.x  0.72
2012 Grimsby JL, Porneala BC, Vassy JL, Yang Q, Florez JC, Dupuis J, Liu T, Yesupriya A, Chang MH, Ned RM, Dowling NF, Khoury MJ, Meigs JB. Race-ethnic differences in the association of genetic loci with HbA1c levels and mortality in U.S. adults: the third National Health and Nutrition Examination Survey (NHANES III). Bmc Medical Genetics. 13: 30. PMID 22540250 DOI: 10.1186/1471-2350-13-30  0.72
2012 Grallert H, Dupuis J, Bis JC, Dehghan A, Barbalic M, Baumert J, Lu C, Smith NL, Uitterlinden AG, Roberts R, Khuseyinova N, Schnabel RB, Rice KM, Rivadeneira F, Hoogeveen RC, et al. Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies. European Heart Journal. 33: 238-51. PMID 22003152 DOI: 10.1093/eurheartj/ehr372  0.72
2011 Choi SH, Liu C, Dupuis J, Logue MW, Jun G. Using linkage analysis of large pedigrees to guide association analyses. Bmc Proceedings. 5: S79. PMID 22373287 DOI: 10.1186/1753-6561-5-S9-S79  0.56
2011 Chen H, Hendricks AE, Cheng Y, Cupples AL, Dupuis J, Liu CT. Comparison of statistical approaches to rare variant analysis for quantitative traits. Bmc Proceedings. 5: S113. PMID 22373209 DOI: 10.1186/1753-6561-5-S9-S113  0.72
2011 Magnani JW, Rienstra M, Lin H, Sinner MF, Lubitz SA, McManus DD, Dupuis J, Ellinor PT, Benjamin EJ. Atrial fibrillation: current knowledge and future directions in epidemiology and genomics. Circulation. 124: 1982-93. PMID 22042927 DOI: 10.1161/CIRCULATIONAHA.111.039677  0.72
2011 Strawbridge RJ, Dupuis J, Prokopenko I, Barker A, Ahlqvist E, Rybin D, Petrie JR, Travers ME, Bouatia-Naji N, Dimas AS, Nica A, Wheeler E, Chen H, Voight BF, Taneera J, et al. Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes. Diabetes. 60: 2624-34. PMID 21873549 DOI: 10.2337/db11-0415  0.4
2011 Vassy JL, Shrader P, Yang Q, Liu T, Yesupriya A, Chang MH, Dowling NF, Ned RM, Dupuis J, Florez JC, Khoury MJ, Meigs JB. Genetic associations with metabolic syndrome and its quantitative traits by race/ethnicity in the United States. Metabolic Syndrome and Related Disorders. 9: 475-82. PMID 21848424 DOI: 10.1089/met.2011.0021  0.72
2011 Kanoni S, Nettleton JA, Hivert MF, Ye Z, van Rooij FJ, Shungin D, Sonestedt E, Ngwa JS, Wojczynski MK, Lemaitre RN, Gustafsson S, Anderson JS, Tanaka T, Hindy G, Saylor G, ... ... Dupuis J, et al. Total zinc intake may modify the glucose-raising effect of a zinc transporter (SLC30A8) variant: a 14-cohort meta-analysis. Diabetes. 60: 2407-16. PMID 21810599 DOI: 10.2337/db11-0176  0.72
2011 de Miguel-Yanes JM, Manning AK, Shrader P, McAteer JB, Goel A, Hamsten A, Fox CS, Florez JC, Dupuis J, Meigs JB. Variants at the endocannabinoid receptor CB1 gene (CNR1) and insulin sensitivity, type 2 diabetes, and coronary heart disease. Obesity (Silver Spring, Md.). 19: 2031-7. PMID 21633404 DOI: 10.1038/oby.2011.135  0.72
2011 Peloso GM, Dupuis J, Lunetta KL. Evaluation of methods accounting for population structure with pedigree data and continuous outcomes. Genetic Epidemiology. 35: 427-36. PMID 21618600 DOI: 10.1002/gepi.20590  0.72
2011 Dehghan A, Dupuis J, Barbalic M, Bis JC, Eiriksdottir G, Lu C, Pellikka N, Wallaschofski H, Kettunen J, Henneman P, Baumert J, Strachan DP, Fuchsberger C, Vitart V, Wilson JF, et al. Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation. 123: 731-8. PMID 21300955 DOI: 10.1161/CIRCULATIONAHA.110.948570  0.72
2011 Manning AK, LaValley M, Liu CT, Rice K, An P, Liu Y, Miljkovic I, Rasmussen-Torvik L, Harris TB, Province MA, Borecki IB, Florez JC, Meigs JB, Cupples LA, Dupuis J. Meta-analysis of gene-environment interaction: joint estimation of SNP and SNP × environment regression coefficients. Genetic Epidemiology. 35: 11-8. PMID 21181894 DOI: 10.1002/gepi.20546  0.72
2011 de Miguel-Yanes JM, Shrader P, Pencina MJ, Fox CS, Manning AK, Grant RW, Dupuis J, Florez JC, D'Agostino RB, Cupples LA, Meigs JB. Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide polymorphisms. Diabetes Care. 34: 121-5. PMID 20889853 DOI: 10.2337/dc10-1265  0.72
2010 Soranzo N, Sanna S, Wheeler E, Gieger C, Radke D, Dupuis J, Bouatia-Naji N, Langenberg C, Prokopenko I, Stolerman E, Sandhu MS, Heeney MM, Devaney JM, Reilly MP, Ricketts SL, et al. Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways. Diabetes. 59: 3229-39. PMID 20858683 DOI: 10.2337/db10-0502  0.72
2010 Yang Q, Liu T, Shrader P, Yesupriya A, Chang MH, Dowling NF, Ned RM, Dupuis J, Florez JC, Khoury MJ, Meigs JB. Racial/ethnic differences in association of fasting glucose-associated genomic loci with fasting glucose, HOMA-B, and impaired fasting glucose in the U.S. adult population. Diabetes Care. 33: 2370-7. PMID 20805255 DOI: 10.2337/dc10-0898  0.72
2010 Nettleton JA, McKeown NM, Kanoni S, Lemaitre RN, Hivert MF, Ngwa J, van Rooij FJ, Sonestedt E, Wojczynski MK, Ye Z, Tanaka T, Garcia M, Anderson JS, Follis JL, Djousse L, ... ... Dupuis J, et al. Interactions of dietary whole-grain intake with fasting glucose- and insulin-related genetic loci in individuals of European descent: a meta-analysis of 14 cohort studies. Diabetes Care. 33: 2684-91. PMID 20693352 DOI: 10.2337/dc10-1150  0.72
2010 Voight BF, Scott LJ, Steinthorsdottir V, Morris AP, Dina C, Welch RP, Zeggini E, Huth C, Aulchenko YS, Thorleifsson G, McCulloch LJ, Ferreira T, Grallert H, Amin N, Wu G, ... ... Dupuis J, et al. Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nature Genetics. 42: 579-89. PMID 20581827 DOI: 10.1038/ng.609  0.72
2010 Wang TJ, Zhang F, Richards JB, Kestenbaum B, van Meurs JB, Berry D, Kiel DP, Streeten EA, Ohlsson C, Koller DL, Peltonen L, Cooper JD, O'Reilly PF, Houston DK, Glazer NL, ... ... Dupuis J, et al. Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet. 376: 180-8. PMID 20541252 DOI: 10.1016/S0140-6736(10)60588-0  0.72
2010 Qi L, Cornelis MC, Kraft P, Stanya KJ, Linda Kao WH, Pankow JS, Dupuis J, Florez JC, Fox CS, Paré G, Sun Q, Girman CJ, Laurie CC, Mirel DB, Manolio TA, et al. Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes. Human Molecular Genetics. 19: 2706-15. PMID 20418489 DOI: 10.1093/hmg/ddq156  0.72
2010 Ingelsson E, Langenberg C, Hivert MF, Prokopenko I, Lyssenko V, Dupuis J, Mägi R, Sharp S, Jackson AU, Assimes TL, Shrader P, Knowles JW, Zethelius B, Abbasi FA, Bergman RN, et al. Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans. Diabetes. 59: 1266-75. PMID 20185807 DOI: 10.2337/db09-1568  0.72
2010 Barbalic M, Dupuis J, Dehghan A, Bis JC, Hoogeveen RC, Schnabel RB, Nambi V, Bretler M, Smith NL, Peters A, Lu C, Tracy RP, Aleksic N, Heeriga J, Keaney JF, et al. Large-scale genomic studies reveal central role of ABO in sP-selectin and sICAM-1 levels. Human Molecular Genetics. 19: 1863-72. PMID 20167578 DOI: 10.1093/hmg/ddq061  0.72
2010 Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, Wheeler E, Glazer NL, Bouatia-Naji N, Gloyn AL, Lindgren CM, Mägi R, Morris AP, Randall J, Johnson T, et al. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nature Genetics. 42: 105-16. PMID 20081858 DOI: 10.1038/ng.520  0.72
2010 Saxena R, Hivert MF, Langenberg C, Tanaka T, Pankow JS, Vollenweider P, Lyssenko V, Bouatia-Naji N, Dupuis J, Jackson AU, Kao WH, Li M, Glazer NL, Manning AK, Luan J, et al. Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nature Genetics. 42: 142-8. PMID 20081857 DOI: 10.1038/ng.521  0.72
2010 Karasik D, Dupuis J, Cho K, Cupples LA, Zhou Y, Kiel DP, Demissie S. Refined QTLs of osteoporosis-related traits by linkage analysis with genome-wide SNPs: Framingham SHARe. Bone. 46: 1114-21. PMID 20064633 DOI: 10.1016/j.bone.2010.01.001  0.72
2010 Schnabel RB, Baumert J, Barbalic M, Dupuis J, Ellinor PT, Durda P, Dehghan A, Bis JC, Illig T, Morrison AC, Jenny NS, Keaney JF, Gieger C, Tilley C, Yamamoto JF, et al. Duffy antigen receptor for chemokines (Darc) polymorphism regulates circulating concentrations of monocyte chemoattractant protein-1 and other inflammatory mediators. Blood. 115: 5289-99. PMID 20040767 DOI: 10.1182/blood-2009-05-221382  0.72
2010 Heid IM, Henneman P, Hicks A, Coassin S, Winkler T, Aulchenko YS, Fuchsberger C, Song K, Hivert MF, Waterworth DM, Timpson NJ, Richards JB, Perry JR, Tanaka T, Amin N, ... ... Dupuis J, et al. Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals. Atherosclerosis. 208: 412-20. PMID 20018283 DOI: 10.1016/j.atherosclerosis.2009.11.035  0.72
2010 Chen MH, Van Eerdewegh P, Vincent QB, Alcais A, Abel L, Dupuis J. Evaluation of approaches to identify associated SNPs that explain the linkage evidence in nuclear families with affected siblings. Human Heredity. 69: 104-19. PMID 19996608 DOI: 10.1159/000264448  0.32
2009 Schnabel RB, Lunetta KL, Larson MG, Dupuis J, Lipinska I, Rong J, Chen MH, Zhao Z, Yamamoto JF, Meigs JB, Nicaud V, Perret C, Zeller T, Blankenberg S, Tiret L, et al. The relation of genetic and environmental factors to systemic inflammatory biomarker concentrations. Circulation. Cardiovascular Genetics. 2: 229-37. PMID 20031590 DOI: 10.1161/CIRCGENETICS.108.804245  0.72
2009 Manning AK, Ngwa JS, Hendricks AE, Liu CT, Johnson AD, Dupuis J, Cupples LA. Incorporating biological knowledge in the search for gene x gene interaction in genome-wide association studies. Bmc Proceedings. 3: S81. PMID 20018077  0.56
2009 Hendricks AE, Zhu Y, Dupuis J. Genome-wide association and linkage analysis of quantitative traits: comparison of likelihood-ratio test and conditional score statistic. Bmc Proceedings. 3: S100. PMID 20017964  0.4
2009 Richards JB, Waterworth D, O'Rahilly S, Hivert MF, Loos RJ, Perry JR, Tanaka T, Timpson NJ, Semple RK, Soranzo N, Song K, Rocha N, Grundberg E, Dupuis J, Florez JC, et al. A genome-wide association study reveals variants in ARL15 that influence adiponectin levels. Plos Genetics. 5: e1000768. PMID 20011104 DOI: 10.1371/journal.pgen.1000768  0.72
2009 Cho K, Dupuis J. Handling linkage disequilibrium in qualitative trait linkage analysis using dense SNPs: a two-step strategy. Bmc Genetics. 10: 44. PMID 19664279 DOI: 10.1186/1471-2156-10-44  0.72
2009 Heard-Costa NL, Zillikens MC, Monda KL, Johansson A, Harris TB, Fu M, Haritunians T, Feitosa MF, Aspelund T, Eiriksdottir G, Garcia M, Launer LJ, Smith AV, Mitchell BD, McArdle PF, ... ... Dupuis J, et al. NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium. Plos Genetics. 5: e1000539. PMID 19557197 DOI: 10.1371/journal.pgen.1000539  0.72
2009 Dupuis J, Shi J, Manning AK, Benjamin EJ, Meigs JB, Cupples LA, Siegmund D. Mapping quantitative traits in unselected families: algorithms and examples. Genetic Epidemiology. 33: 617-27. PMID 19278016 DOI: 10.1002/gepi.20413  0.72
2009 Lieb W, Manning AK, Florez JC, Dupuis J, Cupples LA, McAteer JB, Vasan RS, Hoffmann U, O'Donnell CJ, Meigs JB, Fox CS. Variants in the CNR1 and the FAAH genes and adiposity traits in the community. Obesity (Silver Spring, Md.). 17: 755-60. PMID 19165169 DOI: 10.1038/oby.2008.608  0.72
2009 Kääb S, Darbar D, van Noord C, Dupuis J, Pfeufer A, Newton-Cheh C, Schnabel R, Makino S, Sinner MF, Kannankeril PJ, Beckmann BM, Choudry S, Donahue BS, Heeringa J, Perz S, et al. Large scale replication and meta-analysis of variants on chromosome 4q25 associated with atrial fibrillation. European Heart Journal. 30: 813-9. PMID 19141561 DOI: 10.1093/eurheartj/ehn578  0.72
2009 Schnabel R, Dupuis J, Larson MG, Lunetta KL, Robins SJ, Zhu Y, Rong J, Yin X, Stirnadel HA, Nelson JJ, Wilson PW, Keaney JF, Vasan RS, Benjamin EJ. Clinical and genetic factors associated with lipoprotein-associated phospholipase A2 in the Framingham Heart Study. Atherosclerosis. 204: 601-7. PMID 19135199 DOI: 10.1016/j.atherosclerosis.2008.10.030  0.72
2009 Hivert MF, Manning AK, McAteer JB, Dupuis J, Fox CS, Cupples LA, Meigs JB, Florez JC. Association of variants in RETN with plasma resistin levels and diabetes-related traits in the Framingham Offspring Study. Diabetes. 58: 750-6. PMID 19074981 DOI: 10.2337/db08-1339  0.72
2009 Kathiresan S, Willer CJ, Peloso GM, Demissie S, Musunuru K, Schadt EE, Kaplan L, Bennett D, Li Y, Tanaka T, Voight BF, Bonnycastle LL, Jackson AU, Crawford G, Surti A, ... ... Dupuis J, et al. Common variants at 30 loci contribute to polygenic dyslipidemia. Nature Genetics. 41: 56-65. PMID 19060906 DOI: 10.1038/ng.291  0.72
2009 Liu C, Yang Q, Adrienne Cupples L, Meigs JB, Dupuis J. Selection of the most informative individuals from families with multiple siblings for association studies. Genetic Epidemiology. 33: 299-307. PMID 19025786 DOI: 10.1002/gepi.20380  0.56
2008 Meigs JB, Shrader P, Sullivan LM, McAteer JB, Fox CS, Dupuis J, Manning AK, Florez JC, Wilson PW, D'Agostino RB, Cupples LA. Genotype score in addition to common risk factors for prediction of type 2 diabetes. The New England Journal of Medicine. 359: 2208-19. PMID 19020323 DOI: 10.1056/NEJMoa0804742  0.72
2008 Hivert MF, Manning AK, McAteer JB, Florez JC, Dupuis J, Fox CS, O'Donnell CJ, Cupples LA, Meigs JB. Common variants in the adiponectin gene (ADIPOQ) associated with plasma adiponectin levels, type 2 diabetes, and diabetes-related quantitative traits: the Framingham Offspring Study. Diabetes. 57: 3353-9. PMID 18776141 DOI: 10.2337/db08-0700  0.72
2008 Meigs JB, Manning AK, Dupuis J, Liu C, Florez JC, Cupples LA. Ordered stratification to reduce heterogeneity in linkage to diabetes-related quantitative traits. Obesity (Silver Spring, Md.). 16: 2314-22. PMID 18719643 DOI: 10.1038/oby.2008.354  0.72
2008 Liu C, Batliwalla F, Li W, Lee A, Roubenoff R, Beckman E, Khalili H, Damle A, Kern M, Furie R, Dupuis J, Plenge RM, Coenen MJ, Behrens TW, Carulli JP, et al. Genome-wide association scan identifies candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis. Molecular Medicine (Cambridge, Mass.). 14: 575-81. PMID 18615156 DOI: 10.2119/2008-00056.Liu  0.72
2008 Schnabel R, Larson MG, Dupuis J, Lunetta KL, Lipinska I, Meigs JB, Yin X, Rong J, Vita JA, Newton-Cheh C, Levy D, Keaney JF, Vasan RS, Mitchell GF, Benjamin EJ. Relations of inflammatory biomarkers and common genetic variants with arterial stiffness and wave reflection. Hypertension. 51: 1651-7. PMID 18426996 DOI: 10.1161/HYPERTENSIONAHA.107.105668  0.48
2008 Stolerman ES, Manning AK, McAteer JB, Dupuis J, Fox CS, Cupples LA, Meigs JB, Florez JC. Haplotype structure of the ENPP1 Gene and Nominal Association of the K121Q missense single nucleotide polymorphism with glycemic traits in the Framingham Heart Study. Diabetes. 57: 1971-7. PMID 18426862 DOI: 10.2337/db08-0266  0.72
2008 Cho K, Demissie S, Dupuis J, Cupples LA, Kathiresan S, Beck TJ, Karasik D, Kiel DP. Polymorphisms in the endothelial nitric oxide synthase gene and bone density/ultrasound and geometry in humans. Bone. 42: 53-60. PMID 17980690 DOI: 10.1016/j.bone.2007.09.051  0.72
2007 Chen MH, Cui J, Guo CY, Cupples LA, Van Eerdewegh P, Dupuis J, Yang Q. Joint modeling of linkage and association using affected sib-pair data. Bmc Proceedings. 1: S38. PMID 18466536  0.56
2007 Cho K, Yang Q, Dupuis J. Handling linkage disequilibrium in linkage analysis using dense single-nucleotide polymorphisms. Bmc Proceedings. 1: S161. PMID 18466507  0.72
2007 Cordell HJ, de Andrade M, Babron MC, Bartlett CW, Beyene J, Bickeböller H, Culverhouse R, Cupples LA, Daw EW, Dupuis J, Falk CT, Ghosh S, Goddard KA, Goode EL, Hauser ER, et al. Genetic Analysis Workshop 15: gene expression analysis and approaches to detecting multiple functional loci. Bmc Proceedings. 1: S1. PMID 18466438  0.56
2007 Dupuis J, Siegmund DO, Yakir B. A unified framework for linkage and association analysis of quantitative traits. Proceedings of the National Academy of Sciences of the United States of America. 104: 20210-5. PMID 18077372 DOI: 10.1073/pnas.0707138105  0.72
2007 Dupuis J, Albers K, Allen-Brady K, Cho K, Elston RC, Kappen HJ, Tang H, Thomas A, Thomson G, Tsung E, Yang Q, Zhang W, Zhao K, Zheng G, Ziegler JT. Effect of linkage disequilibrium between markers in linkage and association analyses. Genetic Epidemiology. 31: S139-48. PMID 18046770 DOI: 10.1002/gepi.20291  0.72
2007 Yang Q, Biernacka JM, Chen MH, Houwing-Duistermaat JJ, Bergemann TL, Basu S, Fan R, Liu L, Bourgey M, Clerget-Darpoux F, Lin WY, Elston RC, Cupples LA, Apprey V, Cui J, ... Dupuis J, et al. Using linkage and association to identify and model genetic effects: summary of GAW15 Group 4. Genetic Epidemiology. 31: S34-42. PMID 18046758 DOI: 10.1002/gepi.20278  0.56
2007 Meigs JB, Manning AK, Fox CS, Florez JC, Liu C, Cupples LA, Dupuis J. Genome-wide association with diabetes-related traits in the Framingham Heart Study. Bmc Medical Genetics. 8: S16. PMID 17903298 DOI: 10.1186/1471-2350-8-S1-S16  0.72
2007 Cupples LA, Arruda HT, Benjamin EJ, D'Agostino RB, Demissie S, DeStefano AL, Dupuis J, Falls KM, Fox CS, Gottlieb DJ, Govindaraju DR, Guo CY, Heard-Costa NL, Hwang SJ, Kathiresan S, et al. The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports. Bmc Medical Genetics. 8: S1. PMID 17903291 DOI: 10.1186/1471-2350-8-S1-S1  0.72
2007 Maia AL, Dupuis J, Manning A, Liu C, Meigs JB, Cupples LA, Larsen PR, Fox CS. The type 2 deiodinase (DIO2) A/G polymorphism is not associated with glycemic traits: the Framingham Heart Study. Thyroid : Official Journal of the American Thyroid Association. 17: 199-202. PMID 17381351 DOI: 10.1089/thy.2006.0298  0.56
2007 Dupuis J, O'Donnell CJ. Interpreting results of large-scale genetic association studies: Separating gold from fool's gold Journal of the American Medical Association. 297: 529-531. PMID 17284705 DOI: 10.1001/jama.297.5.529  0.72
2006 Meigs JB, Dupuis J, Liu C, O'Donnell CJ, Fox CS, Kathiresan S, Gabriel SB, Larson MG, Yang Q, Herbert AG, Wilson PW, Feng D, Tofler GH, Cupples LA. PAI-1 Gene 4G/5G polymorphism and risk of type 2 diabetes in a population-based sample. Obesity (Silver Spring, Md.). 14: 753-8. PMID 16855181 DOI: 10.1038/oby.2006.85  0.56
2005 Chen MH, Van Eerdewegh P, Dupuis J. Identification of polymorphisms explaining a linkage signal: application to the GAW14 simulated data. Bmc Genetics. 6: S88. PMID 16451703 DOI: 10.1186/1471-2156-6-S1-S88  0.32
2005 Liu C, Cupples LA, Dupuis J. Comparisons of case-selection approaches based on allele sharing and/or disease severity index: application to the GAW14 simulated data. Bmc Genetics. 6: S103. PMID 16451559 DOI: 10.1186/1471-2156-6-S1-S103  0.56
2005 Meigs JB, Dupuis J, Herbert AG, Liu C, Wilson PW, Cupples LA. The insulin gene variable number tandem repeat and risk of type 2 diabetes in a population-based sample of families and unrelated men and women. The Journal of Clinical Endocrinology and Metabolism. 90: 1137-43. PMID 15562019 DOI: 10.1210/jc.2004-1212  0.56
2000 Dupuis J, Van Eerdewegh P. Multipoint linkage analysis of the pseudoautosomal regions, using affected sibling pairs American Journal of Human Genetics. 67: 462-475. PMID 10869236 DOI: 10.1086/303008  0.72
1999 Dupuis J, Siegmund D. Statistical methods for mapping quantitative trait loci from a dense set of markers Genetics. 151: 373-386. PMID 9872974  0.72
1997 Córdoba J, Dupuis J, Gottstein J, Blei AT. Stenosis of a portacaval anastomosis affects circadian locomotor activity in the rat: A multivariable analysis American Journal of Physiology - Gastrointestinal and Liver Physiology. 273. PMID 9435546  0.72
1995 Dupuis J, Brown PO, Siegmund D. Statistical methods for linkage analysis of complex traits from high- resolution maps of identity by descent Genetics. 140: 843-856. PMID 7498758  0.72
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