Year |
Citation |
Score |
2020 |
Xiong R, Zhang L, Li S, Sun Y, Ding M, Wang Y, Zhao Y, Wu Y, Shang W, Jiang X, Shan J, Shen Z, Tong Y, Xu L, Chen Y, et al. Correction to: Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2. Protein & Cell. PMID 33165830 DOI: 10.1007/s13238-020-00801-y |
0.48 |
|
2020 |
Zeng F, Li S, Yang G, Luo Y, Qi T, Liang Y, Yang T, Zhang L, Wang R, Zhu L, Li H, Xu X. Design, synthesis, molecular modeling, and biological evaluation of acrylamide derivatives as potent inhibitors of human dihydroorotate dehydrogenase for the treatment of rheumatoid arthritis. Acta Pharmaceutica Sinica. B. PMID 33078092 DOI: 10.1016/j.apsb.2020.10.008 |
0.48 |
|
2020 |
Xiong R, Zhang L, Li S, Sun Y, Ding M, Wang Y, Zhao Y, Wu Y, Shang W, Jiang X, Shan J, Shen Z, Tong Y, Xu L, Chen Y, et al. Correction to: Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2. Protein & Cell. PMID 33029721 DOI: 10.1007/s13238-020-00792-w |
0.48 |
|
2020 |
Xiong R, Zhang L, Li S, Sun Y, Ding M, Wang Y, Zhao Y, Wu Y, Shang W, Jiang X, Shan J, Shen Z, Tong Y, Xu L, Chen Y, et al. Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2. Protein & Cell. PMID 32754890 DOI: 10.1007/s13238-020-00768-w |
0.48 |
|
2020 |
Zhu L, Shan L, Zhu J, Li L, Li S, Wang L, Wang J, Zhang S, Zhou H, Zhang W, Li H. Discovery of a natural fluorescent probe targeting the Plasmodium falciparum cysteine protease falcipain-2. Science China. Life Sciences. PMID 32048162 DOI: 10.1007/s11427-019-1581-2 |
0.48 |
|
2019 |
Wang D, Liu W, Shen Z, Jiang L, Wang J, Li S, Li H. Deep Learning Based Drug Metabolites Prediction. Frontiers in Pharmacology. 10: 1586. PMID 32082146 DOI: 10.3389/fphar.2019.01586 |
0.48 |
|
2019 |
Zeng F, Quan L, Yang G, Qi T, Zhang L, Li S, Li H, Zhu L, Xu X. Structural Optimization and Structure-Activity Relationship of 4-Thiazolidinone Derivatives as Novel Inhibitors of Human Dihydroorotate Dehydrogenase. Molecules (Basel, Switzerland). 24. PMID 31370178 DOI: 10.3390/molecules24152780 |
0.48 |
|
2019 |
Li Q, Zhang T, Li S, Tong L, Li J, Su Z, Feng F, Sun D, Tong Y, Wang X, Zhao Z, Zhu L, Ding J, Li H, Xie H, et al. Discovery of Potent and Noncovalent Reversible EGFR Kinase Inhibitors of EGFR. Acs Medicinal Chemistry Letters. 10: 869-873. PMID 31223440 DOI: 10.1021/acsmedchemlett.8b00564 |
0.48 |
|
2019 |
Li S, Qin C, Cui S, Xu H, Wu F, Wang J, Su M, Fang X, Li D, Jiao Q, Zhang M, Xia C, Zhu L, Wang R, Li J, et al. Correction to Discovery of a Natural-Product-Derived Preclinical Candidate for Once-Weekly Treatment of Type 2 Diabetes. Journal of Medicinal Chemistry. PMID 30995042 DOI: 10.1021/acs.jmedchem.9b00559 |
0.48 |
|
2019 |
Li S, Qin C, Cui S, Xu H, Wu F, Wang J, Su M, Fang X, Li D, Jiao Q, Zhang M, Xia C, Zhu L, Wang R, Li J, et al. Discovery of a Natural-Product-Derived Preclinical Candidate for Once-Weekly Treatment of Type 2 Diabetes. Journal of Medicinal Chemistry. PMID 30694668 DOI: 10.1021/acs.jmedchem.8b01491 |
0.48 |
|
2018 |
He G, Gong B, Li J, Song Y, Li S, Lu X. An Improved Receptor-Based Pharmacophore Generation Algorithm Guided by Atomic Chemical Characteristics and Hybridization Types. Frontiers in Pharmacology. 9: 1463. PMID 30618755 DOI: 10.3389/fphar.2018.01463 |
0.48 |
|
2018 |
Xiao W, Wang D, Shen Z, Li S, Li H. Multi-Body Interactions in Molecular Docking Program Devised with Key Water Molecules in Protein Binding Sites. Molecules (Basel, Switzerland). 23. PMID 30208655 DOI: 10.3390/molecules23092321 |
0.48 |
|
2018 |
Diao Y, Jiang J, Zhang S, Li S, Shan L, Huang J, Zhang W, Li H. Discovery of Natural Products as Novel and Potent FXR Antagonists by Virtual Screening. Frontiers in Chemistry. 6: 140. PMID 29761098 DOI: 10.3389/fchem.2018.00140 |
0.48 |
|
2018 |
Zheng S, Zhou Y, Fleming J, Zhou Y, Zhang M, Li S, Li H, Sun B, Liu W, Bi L. Structural and genetic analysis of START superfamily protein MSMEG_0129 from Mycobacterium smegmatis. Febs Letters. PMID 29512898 DOI: 10.1002/1873-3468.13024 |
0.48 |
|
2017 |
Zeng F, Qi T, Li C, Li T, Li H, Li S, Zhu L, Xu X. Synthesis, structure-activity relationship and binding mode analysis of 4-thiazolidinone derivatives as novel inhibitors of human dihydroorotate dehydrogenase. Medchemcomm. 8: 1297-1302. PMID 30108840 DOI: 10.1039/c7md00081b |
0.48 |
|
2017 |
Hu X, Wang D, Tong Y, Tong L, Wang X, Zhu L, Xie H, Li S, Yang Y, Xu Y. Design, Synthesis, and Evaluation of Ribose-Modified Anilinopyrimidine Derivatives as EGFR Tyrosine Kinase Inhibitors. Frontiers in Chemistry. 5: 101. PMID 29250520 DOI: 10.3389/fchem.2017.00101 |
0.44 |
|
2017 |
Li E, Wang Y, Yu W, Lv Z, Peng Y, Liu B, Li S, Ho W, Wang Q, Li H, Chang J. Synthesis and biological evaluation of a novel β-D-2'-deoxy-2'-α-fluoro-2'-β-C-(fluoromethyl)uridine phosphoramidate prodrug for the treatment of hepatitis C virus infection. European Journal of Medicinal Chemistry. 143: 107-113. PMID 29172078 DOI: 10.1016/j.ejmech.2017.11.024 |
0.48 |
|
2017 |
Xiao W, He Z, Sun M, Li S, Li H. Statistical Analysis, Investigation and Prediction of the Water Positions in the Binding Sites of Proteins. Journal of Chemical Information and Modeling. PMID 28605584 DOI: 10.1021/acs.jcim.6b00620 |
0.48 |
|
2017 |
Wang X, Shen Y, Wang S, Li S, Zhang W, Liu X, Lai L, Pei J, Li H. PharmMapper 2017 update: a web server for potential drug target identification with a comprehensive target pharmacophore database. Nucleic Acids Research. PMID 28472422 DOI: 10.1093/nar/gkx374 |
0.48 |
|
2016 |
Zhou W, Li S, Lu W, Yuan J, Xu Y, Li H, Huang J, Zhao Z. Isoindole-1,3-dione derivatives as RSK2 inhibitors: Synthesis, molecular docking simulation and SAR analysis Medchemcomm. 7: 292-296. DOI: 10.1039/c5md00469a |
0.36 |
|
2015 |
Li S, Song Y, Liu X, Li H. A Rapid Python-Based Methodology for Target-Focused Combinatorial Library Design. Combinatorial Chemistry & High Throughput Screening. PMID 26522993 |
0.48 |
|
2015 |
Li S, Luan G, Ren X, Song W, Xu L, Xu M, Zhu J, Dong D, Diao Y, Liu X, Zhu L, Wang R, Zhao Z, Xu Y, Li H. Rational Design of Benzylidenehydrazinyl-Substituted Thiazole Derivatives as Potent Inhibitors of Human Dihydroorotate Dehydrogenase with in Vivo Anti-arthritic Activity. Scientific Reports. 5: 14836. PMID 26443076 DOI: 10.1038/srep14836 |
0.36 |
|
2015 |
Zhu J, Han L, Diao Y, Ren X, Xu M, Xu L, Li S, Li Q, Dong D, Huang J, Liu X, Zhao Z, Wang R, Zhu L, Xu Y, et al. Design, synthesis, X-ray crystallographic analysis, and biological evaluation of thiazole derivatives as potent and selective inhibitors of human dihydroorotate dehydrogenase. Journal of Medicinal Chemistry. 58: 1123-39. PMID 25580811 DOI: 10.1021/jm501127s |
0.44 |
|
2014 |
Zhang S, Shan L, Li Q, Wang X, Li S, Zhang Y, Fu J, Liu X, Li H, Zhang W. Systematic Analysis of the Multiple Bioactivities of Green Tea through a Network Pharmacology Approach. Evidence-Based Complementary and Alternative Medicine : Ecam. 2014: 512081. PMID 25525446 DOI: 10.1155/2014/512081 |
0.36 |
|
2014 |
Wang X, Chen H, Yang F, Gong J, Li S, Pei J, Liu X, Jiang H, Lai L, Li H. iDrug: a web-accessible and interactive drug discovery and design platform. Journal of Cheminformatics. 6: 28. PMID 24955134 DOI: 10.1186/1758-2946-6-28 |
0.48 |
|
2013 |
Xu T, Zhang L, Xu S, Yang CY, Luo J, Ding F, Lu X, Liu Y, Tu Z, Li S, Pei D, Cai Q, Li H, Ren X, Wang S, et al. Pyrimido[4,5-d]pyrimidin-4(1H)-one derivatives as selective inhibitors of EGFR threonine790 to methionine790 (T790M) mutants. Angewandte Chemie (International Ed. in English). 52: 8387-90. PMID 23804305 DOI: 10.1002/anie.201302313 |
0.36 |
|
2011 |
Li S, Zhou Y, Lu W, Zhong Y, Song W, Liu K, Huang J, Zhao Z, Xu Y, Liu X, Li H. Identification of inhibitors against p90 ribosomal S6 kinase 2 (RSK2) through structure-based virtual screening with the inhibitor-constrained refined homology model. Journal of Chemical Information and Modeling. 51: 2939-47. PMID 21995341 DOI: 10.1021/ci2002445 |
0.48 |
|
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