Guanghua Xiao, Ph.D. - Publications

Affiliations: 
2006 University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Biostatistics Biology, Bioinformatics Biology

60 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Li Q, Wang X, Liang F, Yi F, Xie Y, Gazdar A, Xiao G. A Bayesian hidden Potts mixture model for analyzing lung cancer pathology images. Biostatistics (Oxford, England). PMID 29788035 DOI: 10.1093/biostatistics/kxy019  0.56
2017 Li X, Wang X, Xiao G. A comparative study of rank aggregation methods for partial and top ranked lists in genomic applications. Briefings in Bioinformatics. PMID 28968705 DOI: 10.1093/bib/bbx101  0.56
2017 Jia G, Wang X, Xiao G. A permutation-based non-parametric analysis of CRISPR screen data. Bmc Genomics. 18: 545. PMID 28724352 DOI: 10.1186/s12864-017-3938-5  0.56
2017 Li L, Wang X, Xiao G, Gazdar A. Integrative gene set enrichment analysis utilizing isoform-specific expression. Genetic Epidemiology. PMID 28580727 DOI: 10.1002/gepi.22052  0.56
2017 Yu D, Lim J, Wang X, Liang F, Xiao G. Enhanced construction of gene regulatory networks using hub gene information. Bmc Bioinformatics. 18: 186. PMID 28335719 DOI: 10.1186/s12859-017-1576-1  0.56
2015 Duan L, Rai G, Roggero C, Zhang QJ, Wei Q, Ma SH, Zhou Y, Santoyo J, Martinez ED, Xiao G, Raj GV, Jadhav A, Simeonov A, Maloney DJ, Rizo J, et al. KDM4/JMJD2 Histone Demethylase Inhibitors Block Prostate Tumor Growth by Suppressing the Expression of AR and BMYB-Regulated Genes. Chemistry & Biology. PMID 26364928 DOI: 10.1016/j.chembiol.2015.08.007  0.68
2015 Eduati F, Mangravite LM, Wang T, Tang H, Bare JC, Huang R, Norman T, Kellen M, Menden MP, Yang J, Zhan X, Zhong R, Xiao G, Xia M, Abdo N, et al. Prediction of human population responses to toxic compounds by a collaborative competition. Nature Biotechnology. PMID 26258538 DOI: 10.1038/nbt.3299  0.68
2015 Zang X, Chen M, Zhou Y, Xiao G, Xie Y, Wang X. Identifying CDKN3 Gene Expression as a Prognostic Biomarker in Lung Adenocarcinoma via Meta-analysis. Cancer Informatics. 14: 183-91. PMID 26052221 DOI: 10.4137/CIN.S17287  0.56
2015 Wang T, Xiao G, Chu Y, Zhang MQ, Corey DR, Xie Y. Design and bioinformatics analysis of genome-wide CLIP experiments. Nucleic Acids Research. 43: 5263-74. PMID 25958398 DOI: 10.1093/nar/gkv439  0.68
2015 Liu P, Dimitrov I, Andrews T, Crane DE, Dariotis JK, Desmond J, Dumas J, Gilbert G, Kumar A, Maclntosh BJ, Tucholka A, Yang S, Xiao G, Lu H. Multisite evaluations of a T2 -relaxation-under-spin-tagging (TRUST) MRI technique to measure brain oxygenation. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. PMID 25845468 DOI: 10.1002/mrm.25627  0.68
2015 Yu D, Son W, Lim J, Xiao G. Statistical completion of a partially identified graph with applications for the estimation of gene regulatory networks. Biostatistics (Oxford, England). PMID 25837438 DOI: 10.1093/biostatistics/kxv013  0.68
2015 Tang H, Sebti S, Titone R, Zhou Y, Isidoro C, Ross TS, Hibshoosh H, Xiao G, Packer M, Xie Y, Levine B. Decreased BECN1 mRNA Expression in Human Breast Cancer is Associated with Estrogen Receptor-Negative Subtypes and Poor Prognosis. Ebiomedicine. 2: 255-263. PMID 25825707 DOI: 10.1016/j.ebiom.2015.01.008  0.68
2015 Xu F, Liu P, Pascual JM, Xiao G, Huang H, Lu H. Acute effect of glucose on cerebral blood flow, blood oxygenation, and oxidative metabolism. Human Brain Mapping. 36: 707-16. PMID 25324201 DOI: 10.1002/hbm.22658  0.68
2014 Zhong R, Dong X, Levine B, Xie Y, Xiao G. iScreen: Image-Based High-Content RNAi Screening Analysis Tools. Journal of Biomolecular Screening. PMID 25548139 DOI: 10.1177/1087057114564348  0.68
2014 Bansal M, Yang J, Karan C, Menden MP, Costello JC, Tang H, Xiao G, Li Y, Allen J, Zhong R, Chen B, Kim M, Wang T, Heiser LM, Realubit R, et al. A community computational challenge to predict the activity of pairs of compounds. Nature Biotechnology. 32: 1213-22. PMID 25419740 DOI: 10.1038/nbt.3052  0.68
2014 Zhong R, Allen JD, Xiao G, Xie Y. Ensemble-based network aggregation improves the accuracy of gene network reconstruction. Plos One. 9: e106319. PMID 25390635 DOI: 10.1371/journal.pone.0106319  0.68
2014 An Z, Tassa A, Thomas C, Zhong R, Xiao G, Fotedar R, Tu BP, Klionsky DJ, Levine B. Autophagy is required for G₁/G₀ quiescence in response to nitrogen starvation in Saccharomyces cerevisiae. Autophagy. 10: 1702-11. PMID 25126732 DOI: 10.4161/auto.32122  0.68
2014 Tsai YS, Lai CL, Lai CH, Chang KH, Wu K, Tseng SF, Fazli L, Gleave M, Xiao G, Gandee L, Sharifi N, Moro L, Tzai TS, Hsieh JT. The role of homeostatic regulation between tumor suppressor DAB2IP and oncogenic Skp2 in prostate cancer growth. Oncotarget. 5: 6425-36. PMID 25115390  0.68
2014 Gupta S, Sun H, Yi S, Storm J, Xiao G, Balasubramanian BA, Zhang S, Ashfaq R, Rockey DC. Molecular markers of carcinogenesis for risk stratification of individuals with colorectal polyps: a case-control study. Cancer Prevention Research (Philadelphia, Pa.). 7: 1023-34. PMID 25092825 DOI: 10.1158/1940-6207.CAPR-14-0140  0.68
2014 O'Bryant SE, Xiao G, Zhang F, Edwards M, German DC, Yin X, Como T, Reisch J, Huebinger RM, Graff-Radford N, Dickson D, Barber R, Hall J, O'Suilleabhain P, Grammas P. Validation of a serum screen for Alzheimer's disease across assay platforms, species, and tissues. Journal of Alzheimer's Disease : Jad. 42: 1325-35. PMID 25024345 DOI: 10.3233/JAD-141041  0.68
2014 Zhong R, Kim J, Kim HS, Kim M, Lum L, Levine B, Xiao G, White MA, Xie Y. Computational detection and suppression of sequence-specific off-target phenotypes from whole genome RNAi screens. Nucleic Acids Research. 42: 8214-22. PMID 24972830 DOI: 10.1093/nar/gku306  0.68
2014 Yang J, Wang X, Kim M, Xie Y, Xiao G. Detection of candidate tumor driver genes using a fully integrated Bayesian approach. Statistics in Medicine. 33: 1784-800. PMID 24347204 DOI: 10.1002/sim.6066  0.56
2014 O'Bryant SE, Xiao G, Barber R, Cullum CM, Weiner M, Hall J, Edwards M, Grammas P, Wilhelmsen K, Doody R, Diaz-Arrastia R. Molecular neuropsychology: creation of test-specific blood biomarker algorithms. Dementia and Geriatric Cognitive Disorders. 37: 45-57. PMID 24107792 DOI: 10.1159/000345605  0.68
2013 Potts MB, Kim HS, Fisher KW, Hu Y, Carrasco YP, Bulut GB, Ou YH, Herrera-Herrera ML, Cubillos F, Mendiratta S, Xiao G, Hofree M, Ideker T, Xie Y, Huang LJ, et al. Using functional signature ontology (FUSION) to identify mechanisms of action for natural products. Science Signaling. 6: ra90. PMID 24129700 DOI: 10.1126/scisignal.2004657  0.68
2013 Wei Y, Zou Z, Becker N, Anderson M, Sumpter R, Xiao G, Kinch L, Koduru P, Christudass CS, Veltri RW, Grishin NV, Peyton M, Minna J, Bhagat G, Levine B. EGFR-mediated Beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistance. Cell. 154: 1269-84. PMID 24034250 DOI: 10.1016/j.cell.2013.08.015  0.68
2013 He C, Wei Y, Sun K, Li B, Dong X, Zou Z, Liu Y, Kinch LN, Khan S, Sinha S, Xavier RJ, Grishin NV, Xiao G, Eskelinen EL, Scherer PE, et al. Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism. Cell. 154: 1085-99. PMID 23954414 DOI: 10.1016/j.cell.2013.07.035  0.68
2013 Zhong R, Kim MS, White MA, Xie Y, Xiao G. SbacHTS: spatial background noise correction for high-throughput RNAi screening. Bioinformatics (Oxford, England). 29: 2218-20. PMID 23814141 DOI: 10.1093/bioinformatics/btt358  0.68
2013 Tung KC, Uh J, Mao D, Xu F, Xiao G, Lu H. Alterations in resting functional connectivity due to recent motor task. Neuroimage. 78: 316-24. PMID 23583747 DOI: 10.1016/j.neuroimage.2013.04.006  0.68
2013 Chen M, Zang M, Wang X, Xiao G. A powerful Bayesian meta-analysis method to integrate multiple gene set enrichment studies. Bioinformatics (Oxford, England). 29: 862-9. PMID 23418184 DOI: 10.1093/bioinformatics/btt068  0.68
2013 Tang H, Xiao G, Behrens C, Schiller J, Allen J, Chow CW, Suraokar M, Corvalan A, Mao J, White MA, Wistuba II, Minna JD, Xie Y. A 12-gene set predicts survival benefits from adjuvant chemotherapy in non-small cell lung cancer patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 1577-86. PMID 23357979 DOI: 10.1158/1078-0432.CCR-12-2321  0.68
2013 O'Bryant SE, Xiao G, Edwards M, Devous M, Gupta VB, Martins R, Zhang F, Barber R. Biomarkers of Alzheimer's disease among Mexican Americans. Journal of Alzheimer's Disease : Jad. 34: 841-9. PMID 23313927 DOI: 10.3233/JAD-122074  0.68
2013 Wang X, Zang M, Xiao G. Epigenetic change detection and pattern recognition via Bayesian hierarchical hidden Markov models. Statistics in Medicine. 32: 2292-307. PMID 23097332 DOI: 10.1002/sim.5658  0.68
2012 Zhang Y, Xie Y, Berglund ED, Coate KC, He TT, Katafuchi T, Xiao G, Potthoff MJ, Wei W, Wan Y, Yu RT, Evans RM, Kliewer SA, Mangelsdorf DJ. The starvation hormone, fibroblast growth factor-21, extends lifespan in mice. Elife. 1: e00065. PMID 23066506 DOI: 10.7554/eLife.00065  0.68
2012 Wu K, Gore C, Yang L, Fazli L, Gleave M, Pong RC, Xiao G, Zhang L, Yun EJ, Tseng SF, Kapur P, He D, Hsieh JT. Slug, a unique androgen-regulated transcription factor, coordinates androgen receptor to facilitate castration resistance in prostate cancer. Molecular Endocrinology (Baltimore, Md.). 26: 1496-507. PMID 22745193 DOI: 10.1210/me.2011-1360  0.68
2012 Xu F, Liu P, Pascual JM, Xiao G, Lu H. Effect of hypoxia and hyperoxia on cerebral blood flow, blood oxygenation, and oxidative metabolism. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 32: 1909-18. PMID 22739621 DOI: 10.1038/jcbfm.2012.93  0.68
2012 Han TW, Kato M, Xie S, Wu LC, Mirzaei H, Pei J, Chen M, Xie Y, Allen J, Xiao G, McKnight SL. Cell-free formation of RNA granules: bound RNAs identify features and components of cellular assemblies. Cell. 149: 768-79. PMID 22579282 DOI: 10.1016/j.cell.2012.04.016  0.68
2012 Allen JD, Xie Y, Chen M, Girard L, Xiao G. Comparing statistical methods for constructing large scale gene networks. Plos One. 7: e29348. PMID 22272232 DOI: 10.1371/journal.pone.0029348  0.68
2012 He C, Bassik MC, Moresi V, Sun K, Wei Y, Zou Z, An Z, Loh J, Fisher J, Sun Q, Korsmeyer S, Packer M, May HI, Hill JA, Virgin HW, ... ... Xiao G, et al. Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis. Nature. 481: 511-5. PMID 22258505 DOI: 10.1038/nature10758  0.68
2012 Allen JD, Wang S, Chen M, Girard L, Minna JD, Xie Y, Xiao G. Probe mapping across multiple microarray platforms. Briefings in Bioinformatics. 13: 547-54. PMID 22199380 DOI: 10.1093/bib/bbr076  0.68
2012 Hoshiyama H, Tang J, Batten K, Xiao G, Rouillard JM, Shay JW, Xie Y, Wright WE. Development of methods for quantitative comparison of pooled shRNAs by mass sequencing. Journal of Biomolecular Screening. 17: 258-65. PMID 21956173 DOI: 10.1177/1087057111423101  0.68
2011 O'Bryant SE, Xiao G, Barber R, Huebinger R, Wilhelmsen K, Edwards M, Graff-Radford N, Doody R, Diaz-Arrastia R. A blood-based screening tool for Alzheimer's disease that spans serum and plasma: findings from TARC and ADNI. Plos One. 6: e28092. PMID 22163278 DOI: 10.1371/journal.pone.0028092  0.68
2011 Orvedahl A, Sumpter R, Xiao G, Ng A, Zou Z, Tang Y, Narimatsu M, Gilpin C, Sun Q, Roth M, Forst CV, Wrana JL, Zhang YE, Luby-Phelps K, Xavier RJ, et al. Image-based genome-wide siRNA screen identifies selective autophagy factors. Nature. 480: 113-7. PMID 22020285 DOI: 10.1038/nature10546  0.68
2011 O'Bryant SE, Xiao G, Barber R, Reisch J, Hall J, Cullum CM, Doody R, Fairchild T, Adams P, Wilhelmsen K, Diaz-Arrastia R. A blood-based algorithm for the detection of Alzheimer's disease. Dementia and Geriatric Cognitive Disorders. 32: 55-62. PMID 21865746 DOI: 10.1159/000330750  0.68
2011 Xiao G, Wang X, Khodursky AB. Modeling Three-Dimensional Chromosome Structures Using Gene Expression Data. Journal of the American Statistical Association. 106: 61-72. PMID 21760653 DOI: 10.1198/jasa.2010.ap0950  0.68
2011 Aslan S, Huang H, Uh J, Mishra V, Xiao G, van Osch MJ, Lu H. White matter cerebral blood flow is inversely correlated with structural and functional connectivity in the human brain. Neuroimage. 56: 1145-53. PMID 21385618 DOI: 10.1016/j.neuroimage.2011.02.082  0.68
2010 O'Bryant SE, Xiao G, Barber R, Reisch J, Doody R, Fairchild T, Adams P, Waring S, Diaz-Arrastia R. A serum protein-based algorithm for the detection of Alzheimer disease. Archives of Neurology. 67: 1077-81. PMID 20837851 DOI: 10.1001/archneurol.2010.215  0.68
2010 LaPlant Q, Vialou V, Covington HE, Dumitriu D, Feng J, Warren BL, Maze I, Dietz DM, Watts EL, Iñiguez SD, Koo JW, Mouzon E, Renthal W, Hollis F, Wang H, ... ... Xiao G, et al. Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens. Nature Neuroscience. 13: 1137-43. PMID 20729844 DOI: 10.1038/nn.2619  0.68
2010 Xie Y, Pan W, Jeong KS, Xiao G, Khodursky AB. A Bayesian approach to joint modeling of protein-DNA binding, gene expression and sequence data. Statistics in Medicine. 29: 489-503. PMID 20049751 DOI: 10.1002/sim.3815  0.68
2010 Lu H, Yezhuvath US, Xiao G. Improving fMRI sensitivity by normalization of basal physiologic state. Human Brain Mapping. 31: 80-7. PMID 19585589 DOI: 10.1002/hbm.20846  0.68
2009 Wilkinson MB, Xiao G, Kumar A, LaPlant Q, Renthal W, Sikder D, Kodadek TJ, Nestler EJ. Imipramine treatment and resiliency exhibit similar chromatin regulation in the mouse nucleus accumbens in depression models. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 7820-32. PMID 19535594 DOI: 10.1523/JNEUROSCI.0932-09.2009  0.68
2009 Renthal W, Kumar A, Xiao G, Wilkinson M, Covington HE, Maze I, Sikder D, Robison AJ, LaPlant Q, Dietz DM, Russo SJ, Vialou V, Chakravarty S, Kodadek TJ, Stack A, et al. Genome-wide analysis of chromatin regulation by cocaine reveals a role for sirtuins. Neuron. 62: 335-48. PMID 19447090 DOI: 10.1016/j.neuron.2009.03.026  0.68
2009 Yezhuvath US, Lewis-Amezcua K, Varghese R, Xiao G, Lu H. On the assessment of cerebrovascular reactivity using hypercapnia BOLD MRI. Nmr in Biomedicine. 22: 779-86. PMID 19388006 DOI: 10.1002/nbm.1392  0.68
2009 Sakata I, Nakano Y, Osborne-Lawrence S, Rovinsky SA, Lee CE, Perello M, Anderson JG, Coppari R, Xiao G, Lowell BB, Elmquist JK, Zigman JM. Characterization of a novel ghrelin cell reporter mouse. Regulatory Peptides. 155: 91-8. PMID 19361544 DOI: 10.1016/j.regpep.2009.04.001  0.68
2009 Park S, Hatanpaa KJ, Xie Y, Mickey BE, Madden CJ, Raisanen JM, Ramnarain DB, Xiao G, Saha D, Boothman DA, Zhao D, Bachoo RM, Pieper RO, Habib AA. The receptor interacting protein 1 inhibits p53 induction through NF-kappaB activation and confers a worse prognosis in glioblastoma. Cancer Research. 69: 2809-16. PMID 19339267 DOI: 10.1158/0008-5472.CAN-08-4079  0.68
2009 Xiao G, Reilly C, Khodursky AB. Improved detection of differentially expressed genes through incorporation of gene locations. Biometrics. 65: 805-14. PMID 19173705 DOI: 10.1111/j.1541-0420.2008.01161.x  0.68
2008 Pulipparacharuvil S, Renthal W, Hale CF, Taniguchi M, Xiao G, Kumar A, Russo SJ, Sikder D, Dewey CM, Davis MM, Greengard P, Nairn AC, Nestler EJ, Cowan CW. Cocaine regulates MEF2 to control synaptic and behavioral plasticity. Neuron. 59: 621-33. PMID 18760698 DOI: 10.1016/j.neuron.2008.06.020  0.68
2008 Hatanpaa KJ, Bigio EH, Cairns NJ, Womack KB, Weintraub S, Morris JC, Foong C, Xiao G, Hladik C, Mantanona TY, White CL. TAR DNA-binding protein 43 immunohistochemistry reveals extensive neuritic pathology in FTLD-U: a midwest-southwest consortium for FTLD study. Journal of Neuropathology and Experimental Neurology. 67: 271-9. PMID 18379440 DOI: 10.1097/NEN.0b013e31816a12a6  0.68
2008 Zachariou V, Liu R, LaPlant Q, Xiao G, Renthal W, Chan GC, Storm DR, Aghajanian G, Nestler EJ. Distinct roles of adenylyl cyclases 1 and 8 in opiate dependence: behavioral, electrophysiological, and molecular studies. Biological Psychiatry. 63: 1013-21. PMID 18222416 DOI: 10.1016/j.biopsych.2007.11.021  0.68
2007 Renthal W, Maze I, Krishnan V, Covington HE, Xiao G, Kumar A, Russo SJ, Graham A, Tsankova N, Kippin TE, Kerstetter KA, Neve RL, Haggarty SJ, McKinsey TA, Bassel-Duby R, et al. Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli. Neuron. 56: 517-29. PMID 17988634 DOI: 10.1016/j.neuron.2007.09.032  0.68
2006 Xiao G, Martinez-Vaz B, Pan W, Khodursky AB. Operon information improves gene expression estimation for cDNA microarrays. Bmc Genomics. 7: 87. PMID 16630355 DOI: 10.1186/1471-2164-7-87  0.68
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