Melvin E. Andersen - Publications

Affiliations: 
Environmental Sciences & Engineering University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Toxicology

84 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Stefanowicz AJ, Recio L, Black MB, Beames T, Andersen ME, Stern RA, Clewell RA, McMullen PD, Hartman JK, Ranade A. Comparison of Rat Hepatocyte 2D-Monocultures and Hepatocytes Non-Parenchymal Cell Co-Cultures for Assessing Chemical Toxicity. International Journal of Toxicology. 10915818221139471. PMID 36523256 DOI: 10.1177/10915818221139471  0.654
2022 Nicolas CI, Linakis MW, Minto MS, Mansouri K, Clewell RA, Yoon M, Wambaugh JF, Patlewicz G, McMullen PD, Andersen ME, Clewell Iii HJ. Estimating provisional margins of exposure for data-poor chemicals using high-throughput computational methods. Frontiers in Pharmacology. 13: 980747. PMID 36278238 DOI: 10.3389/fphar.2022.980747  0.652
2022 Andersen ME. Assessing modes of action, measures of tissue dose and human relevance of rodent toxicity endpoints with octamethylcyclotetrasiloxane (D4). Toxicology Letters. 357: 57-72. PMID 34995712 DOI: 10.1016/j.toxlet.2021.12.020  0.303
2021 Efremenko A, Balbuena P, Clewell RA, Black M, Pluta L, Andersen ME, Gentry PR, Yager JW, Clewell HJ. Time-dependent genomic response in primary human uroepithelial cells exposed to arsenite for up to 60 days. Toxicology. 461: 152893. PMID 34425169 DOI: 10.1016/j.tox.2021.152893  0.645
2020 Clewell RA, Leonard JA, Nicolas CI, Campbell J, Yoon M, Efremenko AY, McMullen PD, Andersen ME, Clewell HJ, Phillips KA, Tan YM. Application of a combined aggregate exposure pathway and adverse outcome pathway (AEP-AOP) approach to inform a cumulative risk assessment: A case study with phthalates. Toxicology in Vitro : An International Journal Published in Association With Bibra. 104855. PMID 32278033 DOI: 10.1016/J.Tiv.2020.104855  0.681
2020 Ramoju S, Andersen M, Poddalgoda D, Nong A, Karyakina N, Shilnikova N, Krishnan K, Krewski D. Derivation of whole blood biomonitoring equivalents for lithium for the interpretation of biomonitoring data. Regulatory Toxicology and Pharmacology : Rtp. 111: 104581. PMID 31935483 DOI: 10.1016/J.Yrtph.2020.104581  0.339
2019 Nault R, Bals B, Teymouri F, Black MB, Andersen ME, McMullen PD, Krishnan S, Kuravadi N, Paul N, Kumar S, Kannan K, Jayachandra KC, Alagappan L, Patel BD, Bogen KT, et al. A toxicogenomic approach for the risk assessment of the food contaminant acetamide. Toxicology and Applied Pharmacology. 114872. PMID 31881176 DOI: 10.1016/J.Taap.2019.114872  0.309
2019 Beames T, Moreau M, Roberts LA, Mansouri K, Haider S, Smeltz M, Nicolas CI, Doheny D, Phillips MB, Yoon M, Becker RA, McMullen PD, Andersen ME, Clewell RA, Hartman JK. The role of fit-for-purpose assays within tiered testing approaches: A case study evaluating prioritized estrogen-active compounds in an in vitro human uterotrophic assay. Toxicology and Applied Pharmacology. 114774. PMID 31783037 DOI: 10.1016/J.Taap.2019.114774  0.683
2019 Andersen ME, McMullen PD, Phillips MB, Yoon M, Pendse SN, Clewell HJ, Hartman JK, Moreau M, Becker RA, Clewell RA. Developing context appropriate toxicity testing approaches using new alternative methods (NAMs). Altex. 36: 523-534. PMID 31664457 DOI: 10.14573/Altex.1906261  0.68
2019 McMullen PD, Bhattacharya S, Woods CG, Pendse SN, McBride MT, Soldatow VY, Deisenroth C, LeCluyse EL, Clewell RA, Andersen ME. Identifying qualitative differences in PPARα signaling networks in human and rat hepatocytes and their significance for next generation chemical risk assessment methods. Toxicology in Vitro : An International Journal Published in Association With Bibra. PMID 31628012 DOI: 10.1016/J.Tiv.2019.02.017  0.656
2019 McMullen PD, Pendse SN, Black MB, Mansouri K, Haider S, Andersen ME, Clewell RA. Addressing systematic inconsistencies between in vitro and in vivo transcriptomic mode of action signatures. Toxicology in Vitro : An International Journal Published in Association With Bibra. PMID 30807807 DOI: 10.1016/J.Tiv.2019.02.014  0.674
2018 Haider S, Black MB, Parks BB, Foley B, Wetmore BA, Andersen ME, Clewell RA, Mansouri K, McMullen PD. A Qualitative Modeling Approach for Whole Genome Prediction Using High-Throughput Toxicogenomics Data and Pathway-Based Validation. Frontiers in Pharmacology. 9: 1072. PMID 30333746 DOI: 10.3389/Fphar.2018.01072  0.64
2018 Wetmore BA, Clewell RA, Cholewa B, Parks B, Pendse SN, Black MB, Mansouri K, Haider S, Berg EL, Judson RS, Houck KA, Martin M, Clewell HJ, Andersen ME, Thomas RS, et al. Assessing bioactivity-exposure profiles of fruit and vegetable extracts in the BioMAP profiling system. Toxicology in Vitro : An International Journal Published in Association With Bibra. PMID 30218698 DOI: 10.1016/J.Tiv.2018.09.006  0.654
2018 McMullen PD, Andersen ME, Cholewa B, Clewell HJ, Dunnick K, Hartman J, Mansouri K, Minto MS, Nicolas CI, Phillips M, Slattery S, Yoon M, Clewell RA. Evaluating opportunities for advancing the use of alternative methods in risk assessment through the development of fit-for-purpose in vitro assays. Toxicology in Vitro : An International Journal Published in Association With Bibra. PMID 29391263 DOI: 10.1016/J.Tiv.2018.01.027  0.681
2017 Miller MM, McMullen PD, Andersen ME, Clewell RA. Multiple receptors shape the estrogen response pathway and are critical considerations for the future of in vitro-based risk assessment efforts. Critical Reviews in Toxicology. 1-17. PMID 28675057 DOI: 10.1080/10408444.2017.1289150  0.667
2016 Clewell RA, McMullen PD, Adeleye Y, Carmichael PL, Andersen ME. Pathway Based Toxicology and Fit-for-Purpose Assays. Advances in Experimental Medicine and Biology. 856: 205-230. PMID 27671724 DOI: 10.1007/978-3-319-33826-2_8  0.698
2016 Foley B, Doheny D, Black M, Pendse SN, Wetmore B, Clewell R, Andersen ME, Deisenroth C. Screening ToxCastTM prioritized chemicals for PPARG function in a human adipose-derived stem cell model of adipogenesis. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 27664422 DOI: 10.1093/Toxsci/Kfw186  0.642
2016 Klapacz J, Pottenger LH, Engelward BP, Heinen CD, Johnson GE, Clewell RA, Carmichael PL, Adeleye Y, Andersen ME. Contributions of DNA repair and damage response pathways to the non-linear genotoxic responses of alkylating agents. Mutation Research. Reviews in Mutation Research. 767: 77-91. PMID 27036068 DOI: 10.1016/J.Mrrev.2015.11.001  0.657
2016 Clewell RA, Andersen ME. Approaches for characterizing threshold dose-response relationships for DNA-damage pathways involved in carcinogenicity in vivo and micronuclei formation in vitro. Mutagenesis. PMID 26846943 DOI: 10.1093/Mutage/Gev078  0.666
2016 Clewell R, Miller M, Andersen M. Adverse outcome pathway driven development of human cell-based assays sufficient for safety assessment of estrogenic chemicals Toxicology Letters. 258: S142-S143. DOI: 10.1016/J.Toxlet.2016.06.1554  0.646
2016 Yoon M, Phillips M, Billings D, Balbuena P, Shim J, Burgunder E, Pedersen J, Enders J, Macdonald J, Andersen M, Clewell H. Liver bioreactor and incorporation of metabolism and biokinetics into the integrated cell-based toxicity system Toxicology Letters. 258: S31. DOI: 10.1016/J.Toxlet.2016.06.1219  0.323
2015 Peng H, Wang H, Xue P, Hou Y, Dong J, Zhou T, Qu W, Peng S, Li J, Carmichael PL, Nelson B, Clewell R, Zhang Q, Andersen ME, Pi J. Suppression of NRF2-ARE activity sensitizes chemotherapeutic agent-induced cytotoxicity in human acute monocytic leukemia cells. Toxicology and Applied Pharmacology. PMID 26708503 DOI: 10.1016/J.Taap.2015.12.008  0.638
2015 Zhang Q, Bhattacharya S, Pi J, Clewell RA, Carmichael PL, Andersen ME. Adaptive Posttranslational Control in Cellular Stress Response Pathways and Its Relationship to Toxicity Testing and Safety Assessment. Toxicological Sciences : An Official Journal of the Society of Toxicology. 147: 302-16. PMID 26408567 DOI: 10.1093/Toxsci/Kfv130  0.61
2015 Adeleye Y, Andersen M, Clewell R, Davies M, Dent M, Edwards S, Fowler P, Malcomber S, Nicol B, Scott A, Scott S, Sun B, Westmoreland C, White A, Zhang Q, et al. Implementing Toxicity Testing in the 21st Century (TT21C): Making safety decisions using toxicity pathways, and progress in a prototype risk assessment. Toxicology. 332: 102-11. PMID 24582757 DOI: 10.1016/J.Tox.2014.02.007  0.723
2015 Klapacz J, Pottenger LH, Engelward BP, Heinen CD, Johnson GE, Clewell RA, Carmichael PL, Adeleye Y, Andersen ME. Contributions of DNA repair and damage response pathways to the non-linear genotoxic responses of alkylating agents Mutation Research - Reviews in Mutation Research. DOI: 10.1016/j.mrrev.2015.11.001  0.619
2014 Clewell RA, Sun B, Adeleye Y, Carmichael P, Efremenko A, McMullen PD, Pendse S, Trask OJ, White A, Andersen ME. Profiling dose-dependent activation of p53-mediated signaling pathways by chemicals with distinct mechanisms of DNA damage. Toxicological Sciences : An Official Journal of the Society of Toxicology. 142: 56-73. PMID 25078064 DOI: 10.1093/Toxsci/Kfu153  0.67
2014 McMullen PD, Bhattacharya S, Woods CG, Sun B, Yarborough K, Ross SM, Miller ME, McBride MT, LeCluyse EL, Clewell RA, Andersen ME. A map of the PPARα transcription regulatory network for primary human hepatocytes. Chemico-Biological Interactions. 209: 14-24. PMID 24269660 DOI: 10.1016/J.Cbi.2013.11.006  0.638
2014 Li Z, Sun B, Clewell RA, Adeleye Y, Andersen ME, Zhang Q. Dose-response modeling of etoposide-induced DNA damage response. Toxicological Sciences : An Official Journal of the Society of Toxicology. 137: 371-84. PMID 24241721 DOI: 10.1093/Toxsci/Kft259  0.685
2014 Adeleye Y, Rebecca C, Andersen M, Sun B, White A, Carmichael P, Matt D, Paul F. Application of the TT21C strategy to safety assessment using genetic toxicology as a case study Toxicology Letters. 229: S132. DOI: 10.1016/J.Toxlet.2014.06.470  0.374
2013 Thomas RS, Philbert MA, Auerbach SS, Wetmore BA, Devito MJ, Cote I, Rowlands JC, Whelan MP, Hays SM, Andersen ME, Meek ME, Reiter LW, Lambert JC, Clewell HJ, Stephens ML, et al. Incorporating new technologies into toxicity testing and risk assessment: moving from 21st century vision to a data-driven framework. Toxicological Sciences : An Official Journal of the Society of Toxicology. 136: 4-18. PMID 23958734 DOI: 10.1093/toxsci/kft178  0.344
2013 Lv P, Xue P, Dong J, Peng H, Clewell R, Wang A, Wang Y, Peng S, Qu W, Zhang Q, Andersen ME, Pi J. Keap1 silencing boosts lipopolysaccharide-induced transcription of interleukin 6 via activation of nuclear factor κB in macrophages. Toxicology and Applied Pharmacology. 272: 697-702. PMID 23906629 DOI: 10.1016/J.Taap.2013.07.012  0.587
2013 Sun B, Ross SM, Trask OJ, Carmichael PL, Dent M, White A, Andersen ME, Clewell RA. Assessing dose-dependent differences in DNA-damage, p53 response and genotoxicity for quercetin and curcumin. Toxicology in Vitro : An International Journal Published in Association With Bibra. 27: 1877-87. PMID 23764886 DOI: 10.1016/J.Tiv.2013.05.015  0.668
2013 Wetmore BA, Wambaugh JF, Ferguson SS, Li L, Clewell HJ, Judson RS, Freeman K, Bao W, Sochaski MA, Chu TM, Black MB, Healy E, Allen B, Andersen ME, Wolfinger RD, et al. Relative impact of incorporating pharmacokinetics on predicting in vivo hazard and mode of action from high-throughput in vitro toxicity assays. Toxicological Sciences : An Official Journal of the Society of Toxicology. 132: 327-46. PMID 23358191 DOI: 10.1093/Toxsci/Kft012  0.315
2013 Stephens ML, Andersen M, Becker RA, Betts K, Boekelheide K, Carney E, Chapin R, Devlin D, Fitzpatrick S, Fowle JR, Harlow P, Hartung T, Hoffmann S, Holsapple M, Jacobs A, et al. Evidence-based toxicology for the 21st century: opportunities and challenges. Altex. 30: 74-103. PMID 23338808 DOI: 10.14573/Altex.2013.1.074  0.321
2013 Clewell RA, Thomas A, Willson G, Creasy DM, Andersen ME. A dose response study to assess effects after dietary administration of diisononyl phthalate (DINP) in gestation and lactation on male rat sexual development. Reproductive Toxicology (Elmsford, N.Y.). 35: 70-80. PMID 22944045 DOI: 10.1016/J.Reprotox.2012.07.008  0.636
2013 Clewell RA, Sochaski M, Edwards K, Creasy DM, Willson G, Andersen ME. Disposition of diiosononyl phthalate and its effects on sexual development of the male fetus following repeated dosing in pregnant rats. Reproductive Toxicology (Elmsford, N.Y.). 35: 56-69. PMID 22813627 DOI: 10.1016/J.Reprotox.2012.07.001  0.634
2012 Bhattacharya S, Shoda LK, Zhang Q, Woods CG, Howell BA, Siler SQ, Woodhead JL, Yang Y, McMullen P, Watkins PB, Andersen ME. Modeling drug- and chemical-induced hepatotoxicity with systems biology approaches. Frontiers in Physiology. 3: 462. PMID 23248599 DOI: 10.3389/Fphys.2012.00462  0.329
2012 Campbell JL, Clewell RA, Gentry PR, Andersen ME, Clewell HJ. Physiologically based pharmacokinetic/toxicokinetic modeling. Methods in Molecular Biology (Clifton, N.J.). 929: 439-99. PMID 23007440 DOI: 10.1007/978-1-62703-050-2_18  0.661
2012 Schroeter JD, Dorman DC, Yoon M, Nong A, Taylor MD, Andersen ME, Clewell HJ. Application of a multi-route physiologically based pharmacokinetic model for manganese to evaluate dose-dependent neurological effects in monkeys Toxicological Sciences. 129: 432-446. PMID 22723044 DOI: 10.1093/Toxsci/Kfs212  0.309
2012 Yoon M, Campbell JL, Andersen ME, Clewell HJ. Quantitative in vitro to in vivo extrapolation of cell-based toxicity assay results. Critical Reviews in Toxicology. 42: 633-52. PMID 22667820 DOI: 10.3109/10408444.2012.692115  0.305
2012 LeCluyse EL, Witek RP, Andersen ME, Powers MJ. Organotypic liver culture models: meeting current challenges in toxicity testing. Critical Reviews in Toxicology. 42: 501-48. PMID 22582993 DOI: 10.3109/10408444.2012.682115  0.313
2012 Choi K, Joo H, Campbell JL, Clewell RA, Andersen ME, Clewell HJ. In vitro metabolism of di(2-ethylhexyl) phthalate (DEHP) by various tissues and cytochrome P450s of human and rat. Toxicology in Vitro : An International Journal Published in Association With Bibra. 26: 315-22. PMID 22186153 DOI: 10.1016/J.Tiv.2011.12.002  0.619
2012 Wetmore BA, Wambaugh JF, Ferguson SS, Sochaski MA, Rotroff DM, Freeman K, Clewell HJ, Dix DJ, Andersen ME, Houck KA, Allen B, Judson RS, Singh R, Kavlock RJ, Richard AM, et al. Integration of dosimetry, exposure, and high-throughput screening data in chemical toxicity assessment. Toxicological Sciences : An Official Journal of the Society of Toxicology. 125: 157-74. PMID 21948869 DOI: 10.1093/Toxsci/Kfr254  0.336
2012 Dent M, Adeleye Y, Carmichael P, Clewell R, Davies M, Malcomber S, Scott A, White A, Zhang Q, Andersen M, Ingram J. Making safety decisions based on changes in toxicity pathways: A case study Toxicology Letters. 211: S130. DOI: 10.1016/J.Toxlet.2012.03.477  0.633
2011 Bhattacharya S, Zhang Q, Carmichael PL, Boekelheide K, Andersen ME. Toxicity testing in the 21 century: defining new risk assessment approaches based on perturbation of intracellular toxicity pathways. Plos One. 6: e20887. PMID 21701582 DOI: 10.1371/Journal.Pone.0020887  0.383
2011 Tan YM, Clewell H, Campbell J, Andersen M. Evaluating pharmacokinetic and pharmacodynamic interactions with computational models in supporting cumulative risk assessment. International Journal of Environmental Research and Public Health. 8: 1613-30. PMID 21655141 DOI: 10.3390/Ijerph8051613  0.39
2011 Campbell J, Clewell R, Andersen M, Clewell H. Interpreting biomonitoring data for di-n-butyl and di-(2-ethylhexyl) phthalate metabolites in urine using a physiologically based pharmacokinetic model and reverse dosimetry: Estimation of cumulative in utero exposure Toxicology Letters. 205: S210. DOI: 10.1016/J.Toxlet.2011.05.723  0.654
2011 Clewell R, Sun B, Ross S, Carmichael P, Andersen M. In vitro evaluation of dose-dependent chemically induced DNA damage and p53 pathway response Toxicology Letters. 205: S79. DOI: 10.1016/J.Toxlet.2011.05.295  0.681
2010 Boekelheide K, Andersen ME. A mechanistic redefinition of adverse effects - a key step in the toxicity testing paradigm shift. Altex. 27: 243-52. PMID 21240467 DOI: 10.14573/Altex.2010.4.243  0.344
2010 Andersen ME, Clewell HJ, Bermudez E, Dodd DE, Willson GA, Campbell JL, Thomas RS. Formaldehyde: integrating dosimetry, cytotoxicity, and genomics to understand dose-dependent transitions for an endogenous compound. Toxicological Sciences : An Official Journal of the Society of Toxicology. 118: 716-31. PMID 20884683 DOI: 10.1093/toxsci/kfq303  0.344
2010 Rotroff DM, Wetmore BA, Dix DJ, Ferguson SS, Clewell HJ, Houck KA, Lecluyse EL, Andersen ME, Judson RS, Smith CM, Sochaski MA, Kavlock RJ, Boellmann F, Martin MT, Reif DM, et al. Incorporating human dosimetry and exposure into high-throughput in vitro toxicity screening. Toxicological Sciences : An Official Journal of the Society of Toxicology. 117: 348-58. PMID 20639261 DOI: 10.1093/Toxsci/Kfq220  0.334
2010 Krewski D, Acosta D, Andersen M, Anderson H, Bailar JC, Boekelheide K, Brent R, Charnley G, Cheung VG, Green S, Kelsey KT, Kerkvliet NI, Li AA, McCray L, Meyer O, et al. Toxicity testing in the 21st century: a vision and a strategy. Journal of Toxicology and Environmental Health. Part B, Critical Reviews. 13: 51-138. PMID 20574894 DOI: 10.1080/10937404.2010.483176  0.431
2010 Clewell RA, Campbell JL, Ross SM, Gaido KW, Clewell HJ, Andersen ME. Assessing the relevance of in vitro measures of phthalate inhibition of steroidogenesis for in vivo response. Toxicology in Vitro : An International Journal Published in Association With Bibra. 24: 327-34. PMID 19699292 DOI: 10.1016/J.Tiv.2009.08.003  0.654
2009 Ernstgård L, Andersen M, Dekant W, Sjögren B, Johanson G. Experimental exposure to 1,1,1,3,3-pentafluoropropane (HFC-245fa): uptake and disposition in humans. Toxicological Sciences : An Official Journal of the Society of Toxicology. 113: 326-36. PMID 19915083 DOI: 10.1093/Toxsci/Kfp273  0.333
2009 Tardiff RG, Carson ML, Sweeney LM, Kirman CR, Tan YM, Andersen M, Bevan C, Gargas ML. Derivation of a drinking water equivalent level (DWEL) related to the maximum contaminant level goal for perfluorooctanoic acid (PFOA), a persistent water soluble compound. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 47: 2557-89. PMID 19631249 DOI: 10.1016/J.Fct.2009.07.016  0.308
2009 Clewell RA, Pluta L, Thomas RS, Andersen ME. In utero exposure to chloroquine alters sexual development in the male fetal rat. Toxicology and Applied Pharmacology. 237: 366-74. PMID 19393257 DOI: 10.1016/J.Taap.2009.04.013  0.654
2009 Clewell RA, Kremer JJ, Williams CC, Campbell JL, Sochaski MA, Andersen ME, Borghoff SJ. Kinetics of selected di-n-butyl phthalate metabolites and fetal testosterone following repeated and single administration in pregnant rats. Toxicology. 255: 80-90. PMID 19010379 DOI: 10.1016/J.Tox.2008.10.010  0.656
2008 Andersen ME, Krewski D. Toxicity testing in the 21st century: bringing the vision to life. Toxicological Sciences : An Official Journal of the Society of Toxicology. 107: 324-30. PMID 19074763 DOI: 10.1093/Toxsci/Kfn255  0.349
2008 Clewell HJ, Tan YM, Campbell JL, Andersen ME. Quantitative interpretation of human biomonitoring data. Toxicology and Applied Pharmacology. 231: 122-33. PMID 18589468 DOI: 10.1016/j.taap.2008.04.021  0.313
2008 Clewell RA, Kremer JJ, Williams CC, Campbell JL, Andersen ME, Borghoff SJ. Tissue exposures to free and glucuronidated monobutylyphthalate in the pregnant and fetal rat following exposure to di-n-butylphthalate: evaluation with a PBPK model. Toxicological Sciences : An Official Journal of the Society of Toxicology. 103: 241-59. PMID 18344531 DOI: 10.1093/Toxsci/Kfn054  0.672
2007 Thomas RS, Allen BC, Nong A, Yang L, Bermudez E, Clewell HJ, Andersen ME. A method to integrate benchmark dose estimates with genomic data to assess the functional effects of chemical exposure. Toxicological Sciences : An Official Journal of the Society of Toxicology. 98: 240-8. PMID 17449896 DOI: 10.1093/toxsci/kfm092  0.341
2005 Andersen ME, Dennison JE, Thomas RS, Conolly RB. New directions in incidence-dose modeling Trends in Biotechnology. 23: 122-127. PMID 15734554 DOI: 10.1016/j.tibtech.2005.01.007  0.314
2005 Dybing E, Farmer PB, Andersen M, Fennell TR, Lalljie SPD, Müller DJG, Olin S, Petersen BJ, Schlatter J, Scholz G, Scimeca JA, Slimani N, Törnqvist M, Tuijtelaars S, Verger P. Human exposure and internal dose assessments of acrylamide in food Food and Chemical Toxicology. 43: 365-410. PMID 15680675 DOI: 10.1016/J.Fct.2004.11.004  0.365
2003 Gentry PR, Covington TR, Andersen ME, Clewell HJ. Application of a physiologically based pharmacokinetic model for isopropanol in the derivation of a reference dose and reference concentration. Regulatory Toxicology and Pharmacology : Rtp. 36: 51-68. PMID 12383718 DOI: 10.1006/rtph.2002.1540  0.305
2001 Andersen ME, Dennison JE. Mode of action and tissue dosimetry in current and future risk assessments. The Science of the Total Environment. 274: 3-14. PMID 11453304 DOI: 10.1016/S0048-9697(01)00744-6  0.303
2001 MacGregor JT, Collins JM, Sugiyama Y, Tyson CA, Dean J, Smith L, Andersen M, Curren RD, Houston JB, Kadlubar FF, Kedderis GL, Krishnan K, Li AP, Parchment RE, Thummel K, et al. In vitro human tissue models in risk assessment: report of a consensus-building workshop. Toxicological Sciences : An Official Journal of the Society of Toxicology. 59: 17-36. PMID 11134541 DOI: 10.1093/Toxsci/59.1.17  0.366
2000 Andersen M, Sarangapani R, Gentry R, Clewell H, Covington T, Frederick CB. Application of a hybrid CFD-PBPK nasal dosimetry model in an inhalation risk assessment: an example with acrylic acid. Toxicological Sciences : An Official Journal of the Society of Toxicology. 57: 312-25. PMID 11006361 DOI: 10.1093/Toxsci/57.2.312  0.383
2000 Lau C, Andersen ME, Crawford-Brown DJ, Kavlock RJ, Kimmel CA, Knudsen TB, Muneoka K, Rogers JM, Setzer RW, Smith G, Tyl R. Evalaution of biologically based dose-response modeling for developmental toxicity: A workshop report Regulatory Toxicology and Pharmacology. 31: 190-199. PMID 10854125 DOI: 10.1006/Rtph.1999.1360  0.308
2000 Barton HA, Deisinger PJ, English JC, Gearhart JN, Faber WD, Tyler TR, Banton MI, Teeguarden J, Andersen ME. Family approach for estimating reference concentrations/doses for series of related organic chemicals. Toxicological Sciences : An Official Journal of the Society of Toxicology. 54: 251-61. PMID 10746952 DOI: 10.1093/toxsci/54.1.251  0.318
1999 Bogdanffy MS, Sarangapani R, Plowchalk DR, Jarabek A, Andersen ME. A biologically based risk assessment for vinyl acetate-induced cancer and noncancer inhalation toxicity. Toxicological Sciences : An Official Journal of the Society of Toxicology. 51: 19-35. PMID 10496674 DOI: 10.1093/toxsci/51.1.19  0.331
1999 Andersen ME, Conolly RB, Faustman EM, Kavlock RJ, Portier CJ, Sheehan DM, Wier PJ, Ziese L. Quantitative mechanistically based dose-response modeling with endocrine-active compounds Environmental Health Perspectives. 107: 631-638. PMID 10421774 DOI: 10.1289/Ehp.99107S4631  0.313
1999 Clewell HJ, Gentry PR, Barton HA, Shipp AM, Yager JW, Andersen ME. Requirements for a Biologically Realistic Cancer Risk Assessment for Inorganic Arsenic International Journal of Toxicology. 18: 131-147. DOI: 10.1080/109158199225701  0.321
1998 Andersen ME, Barton HA. The use of biochemical and molecular parameters to estimate dose-response relationships at low levels of exposure. Environmental Health Perspectives. 349-55. PMID 9539029 DOI: 10.1289/ehp.98106s1349  0.317
1997 Barton HA, Andersen ME. Dose-response assessment strategies for endocrine-active compounds. Regulatory Toxicology and Pharmacology : Rtp. 25: 292-305. PMID 9237331 DOI: 10.1006/rtph.1997.1106  0.327
1995 Clewell HJ, Gentry PR, Gearhart JM, Allen BC, Andersen ME. Considering pharmacokinetic and mechanistic information in cancer risk assessments for environmental contaminants: Examples with vinyl chloride and trichloroethylene Chemosphere. 31: 2561-2578. PMID 7670867 DOI: 10.1016/0045-6535(95)00124-Q  0.307
1995 Gargas ML, Medinsky MA, Andersen ME. Pharmacokinetic modeling approaches for describing the uptake, systemic distribution, and disposition of inhaled chemicals. Critical Reviews in Toxicology. 25: 237-54. PMID 7576153 DOI: 10.3109/10408449509089889  0.333
1994 Andersen ME, Krishnan K. Physiologically based pharmacokinetics and cancer risk assessment. Environmental Health Perspectives. 103-8. PMID 8187697 DOI: 10.1289/ehp.94102s1103  0.329
1994 Gearhart JM, Jepson GW, Clewell HJ, Andersen ME, Conolly RB. Physiologically based pharmacokinetic model for the inhibition of acetylcholinesterase by organophosphate esters Environmental Health Perspectives. 102: 51-60. PMID 7737042 DOI: 10.1289/ehp.94102s1151  0.304
1993 Mills JJ, Andersen ME. Dioxin hepatic carcinogenesis: biologically motivated modeling and risk assessment. Toxicology Letters. 68: 177-89. PMID 8516763 DOI: 10.1016/0378-4274(93)90129-L  0.312
1993 Conolly RB, Andersen ME. An approach to mechanism-based cancer risk assessment for formaldehyde Environmental Health Perspectives. 101: 169-176. PMID 8020441 DOI: 10.1289/ehp.93101s6169  0.302
1990 Andersen ME. Tissue dosimetry, physiologically-based pharmacokinetic modeling, and cancer risk assessment. Cell Biology and Toxicology. 5: 405-15. PMID 2627676 DOI: 10.1007/BF00118411  0.312
1990 Corley RA, Mendrala AL, Smith FA, Staats DA, Gargas ML, Conolly RB, Andersen ME, Reitz RH. Development of a physiologically based pharmacokinetic model for chloroform. Toxicology and Applied Pharmacology. 103: 512-27. PMID 2339423 DOI: 10.1016/0041-008X(90)90324-N  0.309
1987 Clewell HJ, Andersen ME. Risk assessment extrapolations and physiological modeling. Toxicology and Industrial Health. 1: 111-31. PMID 3843496 DOI: 10.1177/074823378500100408  0.325
1987 Andersen ME, Clewell HJ, Gargas ML, Smith FA, Reitz RH. Physiologically based pharmacokinetics and the risk assessment process for methylene chloride. Toxicology and Applied Pharmacology. 87: 185-205. PMID 3824380 DOI: 10.1016/0041-008X(87)90281-X  0.309
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