| Year |
Citation |
Score |
| 2020 |
Smith EC, Conklin LS, Hoffman EP, Clemens PR, Mah JK, Finkel RS, Guglieri M, Tulinius M, Nevo Y, Ryan MM, Webster R, Castro D, Kuntz NL, Kerchner L, Morgenroth LP, ... ... Damsker JM, et al. Efficacy and safety of vamorolone in Duchenne muscular dystrophy: An 18-month interim analysis of a non-randomized open-label extension study. Plos Medicine. 17: e1003222. PMID 32956407 DOI: 10.1371/Journal.Pmed.1003222 |
0.316 |
|
| 2019 |
Hoffman EP, Schwartz BD, Mengle-Gaw LJ, Smith EC, Castro D, Mah JK, McDonald CM, Kuntz NL, Finkel RS, Guglieri M, Bushby K, Tulinius M, Nevo Y, Ryan MM, Webster R, ... ... Damsker JM, et al. Vamorolone trial in Duchenne muscular dystrophy shows dose-related improvement of muscle function. Neurology. PMID 31451516 DOI: 10.1212/Wnl.0000000000008168 |
0.303 |
|
| 2019 |
Damsker JM, Cornish MR, Kanneboyina P, Kanneboyina I, Yu Q, Lipson R, Phadke A, Knoblach SM, Panchapakesan K, Morales M, Fiorillo AA, Partridge T, Nagaraju K. Vamorolone, a dissociative steroidal compound, reduces collagen antibody-induced joint damage and inflammation when administered after disease onset. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. PMID 31446438 DOI: 10.1007/S00011-019-01279-Z |
0.368 |
|
| 2018 |
Conklin LS, Merkel PA, Pachman LM, Parikh H, Tawalbeh S, Damsker JM, Cuthbertson DD, Morgan GA, Monach PA, Hathout Y, Nagaraju K, van den Anker J, McAlear CA, Hoffman EP. Serum biomarkers of glucocorticoid response and safety in anti-neutrophil cytoplasmic antibody-associated vasculitis and juvenile dermatomyositis. Steroids. PMID 30352204 DOI: 10.1016/J.Steroids.2018.10.008 |
0.394 |
|
| 2018 |
Conklin LS, Damsker JM, Hoffman EP, Jusko WJ, Mavroudis PD, Schwartz BD, Mengle-Gaw LJ, Smith EC, Mah JK, Guglieri M, Nevo Y, Kuntz N, McDonald CM, Tulinius M, Ryan MM, et al. Phase IIa trial in Duchenne muscular dystrophy shows vamorolone is a first-in-class dissociative steroidal anti-inflammatory drug. Pharmacological Research. PMID 30219580 DOI: 10.1016/J.Phrs.2018.09.007 |
0.325 |
|
| 2018 |
Fiorillo AA, Tully CB, Damsker JM, Nagaraju K, Hoffman EP, Heier CR. Muscle miRNAome shows suppression of chronic inflammatory miRNAs with both prednisone and vamorolone. Physiological Genomics. PMID 29883261 DOI: 10.1152/Physiolgenomics.00134.2017 |
0.302 |
|
| 2018 |
Almeida LEF, Damsker JM, Albani S, Afsar N, Kamimura S, Pratt D, Kleiner DE, Quezado M, Gordish-Dressman H, Quezado ZMN. The corticosteroid compounds prednisolone and vamorolone do not alter the nociception phenotype and exacerbate liver injury in sickle cell mice. Scientific Reports. 8: 6081. PMID 29666400 DOI: 10.1038/S41598-018-24274-6 |
0.389 |
|
| 2018 |
Hoffman EP, Riddle V, Siegler MA, Dickerson D, Backonja M, Kramer WG, Nagaraju K, Gordish-Dressman H, Damsker JM, McCall JM. Phase 1 trial of vamorolone, a first-in-class steroid, shows improvements in side effects via biomarkers bridged to clinical outcomes. Steroids. PMID 29524454 DOI: 10.1016/J.Steroids.2018.02.010 |
0.351 |
|
| 2016 |
Wells E, Kambhampati M, Damsker JM, Gordish-Dressman H, Yadavilli S, Becher OJ, Gittens J, Stampar M, Packer RJ, Nazarian J. Vamorolone, a dissociative steroidal compound, reduces pro-inflammatory cytokine expression in glioma cells and increases activity and survival in a murine model of cortical tumor. Oncotarget. PMID 28030841 DOI: 10.18632/Oncotarget.14070 |
0.425 |
|
| 2016 |
Heier CR, Fiorillo AA, Chaisson E, Gordish-Dressman H, Hathout Y, Damsker JM, Hoffman EP, Conklin LS. Identification of Pathway-Specific Serum Biomarkers of Response to Glucocorticoid and Infliximab Treatment in Children with Inflammatory Bowel Disease. Clinical and Translational Gastroenterology. 7: e192. PMID 27628422 DOI: 10.1038/Ctg.2016.49 |
0.363 |
|
| 2016 |
Hathout Y, Conklin LS, Seol H, Gordish-Dressman H, Brown KJ, Morgenroth LP, Nagaraju K, Heier CR, Damsker JM, van den Anker JN, Henricson E, Clemens PR, Mah JK, McDonald C, Hoffman EP. Serum pharmacodynamic biomarkers for chronic corticosteroid treatment of children. Scientific Reports. 6: 31727. PMID 27530235 DOI: 10.1038/Srep31727 |
0.354 |
|
| 2016 |
Damsker JM, Conklin LS, Sadri S, Dillingham BC, Panchapakesan K, Heier CR, McCall JM, Sandler AD. VBP15, a novel dissociative steroid compound, reduces NFκB-induced expression of inflammatory cytokines in vitro and symptoms of murine trinitrobenzene sulfonic acid-induced colitis. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. PMID 27261270 DOI: 10.1007/S00011-016-0956-8 |
0.382 |
|
| 2016 |
Garvin LM, Chen Y, Damsker JM, Rose MC. A novel dissociative steroid VBP15 reduces MUC5AC gene expression in airway epithelial cells but lacks the GRE mediated transcriptional properties of dexamethasone. Pulmonary Pharmacology & Therapeutics. PMID 27133900 DOI: 10.1016/J.Pupt.2016.04.004 |
0.453 |
|
| 2016 |
Alcala S, Benton A, Watson A, Reeves E, Damsker J, Wang Z, Nagaraju K, Rose M, Hoffman E, Freishtat R. 22: MITOTIC ASYNCHRONY INDUCES A PRO-INFLAMMATORY STATE IN AIRWAY EPITHELIUM Journal of Investigative Medicine. 64: 816.1-816. DOI: 10.1136/jim-2016-000080.38 |
0.316 |
|
| 2015 |
Freishtat RJ, Nino G, Tsegaye Y, Alcala SE, Benton AS, Watson AM, Reeves EK, Haider SK, Damsker JM. Pharmacologically-induced mitotic synchrony in airway epithelial cells as a mechanism of action of anti-inflammatory drugs. Respiratory Research. 16: 132. PMID 26511361 DOI: 10.1186/S12931-015-0293-4 |
0.491 |
|
| 2015 |
Dillingham BC, Knoblach SM, Many GM, Harmon BT, Mullen AM, Heier CR, Bello L, McCall JM, Hoffman EP, Connor EM, Nagaraju K, Reeves EK, Damsker JM. VBP15, a novel anti-inflammatory, is effective at reducing the severity of murine experimental autoimmune encephalomyelitis. Cellular and Molecular Neurobiology. 35: 377-87. PMID 25392236 DOI: 10.1007/S10571-014-0133-Y |
0.471 |
|
| 2015 |
Reeves EK, Hoffman EP, Nagaraju K, Damsker JM, McCall JM. Corrigendum to “VBP15: Preclinical characterization of a novel anti-inflammatory delta 9,11 steroid” [Bioorg. Med. Chem. 21 (2013) 2241–2249] Bioorganic & Medicinal Chemistry. 23: 1664. DOI: 10.1016/J.Bmc.2015.01.034 |
0.401 |
|
| 2014 |
Alcala SE, Benton AS, Watson AM, Kureshi S, Reeves EM, Damsker J, Wang Z, Nagaraju K, Anderson J, Williams AM, Lee AJ, Hayes K, Rose MC, Hoffman EP, Freishtat RJ. Mitotic asynchrony induces transforming growth factor-β1 secretion from airway epithelium. American Journal of Respiratory Cell and Molecular Biology. 51: 363-9. PMID 24669775 DOI: 10.1165/Rcmb.2013-0396Oc |
0.385 |
|
| 2014 |
Wells E, Khambampati M, Yadavilli S, Damsker J, Hoffman E, Packer R, Nazarian J. ET-64 * PRE-CLINICAL ASSESSMENT OF DISSOCIATIVE STEROIDS AS DEXAMETHASONE SUBSTITUTE FOR TREATMENT IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) Neuro-Oncology. 16: v93-v93. DOI: 10.1093/Neuonc/Nou255.61 |
0.372 |
|
| 2013 |
Heier CR, Damsker JM, Yu Q, Dillingham BC, Huynh T, Van der Meulen JH, Sali A, Miller BK, Phadke A, Scheffer L, Quinn J, Tatem K, Jordan S, Dadgar S, Rodriguez OC, et al. VBP15, a novel anti-inflammatory and membrane-stabilizer, improves muscular dystrophy without side effects. Embo Molecular Medicine. 5: 1569-85. PMID 24014378 DOI: 10.1002/Emmm.201302621 |
0.391 |
|
| 2013 |
Damsker JM, Dillingham BC, Rose MC, Balsley MA, Heier CR, Watson AM, Stemmy EJ, Jurjus RA, Huynh T, Tatem K, Uaesoontrachoon K, Berry DM, Benton AS, Freishtat RJ, Hoffman EP, et al. VBP15, a glucocorticoid analogue, is effective at reducing allergic lung inflammation in mice. Plos One. 8: e63871. PMID 23667681 DOI: 10.1371/Journal.Pone.0063871 |
0.663 |
|
| 2013 |
Reeves EK, Hoffman EP, Nagaraju K, Damsker JM, McCall JM. VBP15: preclinical characterization of a novel anti-inflammatory delta 9,11 steroid. Bioorganic & Medicinal Chemistry. 21: 2241-9. PMID 23498916 DOI: 10.1016/J.Bmc.2013.02.009 |
0.398 |
|
| 2012 |
Baudy AR, Reeves EK, Damsker JM, Heier C, Garvin LM, Dillingham BC, McCall J, Rayavarapu S, Wang Z, Vandermeulen JH, Sali A, Jahnke V, Duguez S, DuBois D, Rose MC, et al. Δ-9,11 modification of glucocorticoids dissociates nuclear factor-κB inhibitory efficacy from glucocorticoid response element-associated side effects. The Journal of Pharmacology and Experimental Therapeutics. 343: 225-32. PMID 22743576 DOI: 10.1124/Jpet.112.194340 |
0.399 |
|
| 2012 |
Reeves EK, Rayavarapu S, Damsker JM, Nagaraju K. Glucocorticoid analogues: potential therapeutic alternatives for treating inflammatory muscle diseases. Endocrine, Metabolic & Immune Disorders Drug Targets. 12: 95-103. PMID 22214335 DOI: 10.2174/187153012799279045 |
0.438 |
|
| 2011 |
Stemmy EJ, Balsley MA, Jurjus RA, Damsker JM, Bukrinsky MI, Constant SL. Blocking cyclophilins in the chronic phase of asthma reduces the persistence of leukocytes and disease reactivation. American Journal of Respiratory Cell and Molecular Biology. 45: 991-8. PMID 21493785 DOI: 10.1165/Rcmb.2011-0007Oc |
0.644 |
|
| 2009 |
Beaver LM, Stemmy EJ, Schwartz AM, Damsker JM, Constant SL, Ceryak SM, Patierno SR. Lung inflammation, injury, and proliferative response after repetitive particulate hexavalent chromium exposure. Environmental Health Perspectives. 117: 1896-902. PMID 20049209 DOI: 10.1289/Ehp.0900715 |
0.714 |
|
| 2009 |
Damsker JM, Okwumabua I, Pushkarsky T, Arora K, Bukrinsky MI, Constant SL. Targeting the chemotactic function of CD147 reduces collagen-induced arthritis. Immunology. 126: 55-62. PMID 18557953 DOI: 10.1111/J.1365-2567.2008.02877.X |
0.675 |
|
| 2008 |
Teixeira-Carvalho A, Fujiwara RT, Stemmy EJ, Olive D, Damsker JM, Loukas A, Corrêa-Oliveira R, Constant SL, Bethony JM. Binding of excreted and/or secreted products of adult hookworms to human NK cells in Necator americanus-infected individuals from Brazil. Infection and Immunity. 76: 5810-6. PMID 18838519 DOI: 10.1128/Iai.00419-08 |
0.69 |
|
| 2007 |
Damsker JM, Bukrinsky MI, Constant SL. Preferential chemotaxis of activated human CD4+ T cells by extracellular cyclophilin A. Journal of Leukocyte Biology. 82: 613-8. PMID 17540735 DOI: 10.1189/Jlb.0506317 |
0.687 |
|
| 2007 |
Wolnicka-Glubisz A, Damsker J, Constant S, Corn S, De Fabo E, Noonan F. Deficient inflammatory response to UV radiation in neonatal mice. Journal of Leukocyte Biology. 81: 1352-61. PMID 17369492 DOI: 10.1189/Jlb.1206729 |
0.691 |
|
| 2006 |
Gwinn WM, Damsker JM, Falahati R, Okwumabua I, Kelly-Welch A, Keegan AD, Vanpouille C, Lee JJ, Dent LA, Leitenberg D, Bukrinsky MI, Constant SL. Novel approach to inhibit asthma-mediated lung inflammation using anti-CD147 intervention. Journal of Immunology (Baltimore, Md. : 1950). 177: 4870-9. PMID 16982929 DOI: 10.4049/Jimmunol.177.7.4870 |
0.716 |
|
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