Klaus Ley - Publications

Affiliations: 
University of Virginia, Charlottesville, VA 
Area:
Biomedical Engineering, Statistics

252 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Lin J, Ehinger E, Hanna DB, Qi Q, Wang T, Ghosheh Y, Mueller K, Anastos K, Lazar JM, Mack WJ, Tien PC, Berman JW, Cohen MH, Ofotokun I, Gange S, ... ... Ley K, et al. HIV infection and cardiovascular disease have both shared and distinct monocyte gene expression features: Women's Interagency HIV study. Plos One. 18: e0285926. PMID 37205656 DOI: 10.1371/journal.pone.0285926  0.695
2022 Vallejo J, Saigusa R, Gulati R, Suthahar SSA, Suryawanshi V, Alimadadi A, Durant CP, Ghosheh Y, Roy P, Ehinger E, Pattarabanjird T, Hanna DB, Landay AL, Tracy RP, Lazar JM, ... ... Ley K, et al. Author Correction: Combined protein and transcript single-cell RNA sequencing in human peripheral blood mononuclear cells. Bmc Biology. 20: 237. PMID 36266696 DOI: 10.1186/s12915-022-01440-x  0.705
2022 Vallejo J, Saigusa R, Gulati R, Armstrong Suthahar SS, Suryawanshi V, Alimadadi A, Durant CP, Ghosheh Y, Roy P, Ehinger E, Pattarabanjird T, Hanna DB, Landay AL, Tracy RP, Lazar JM, ... ... Ley K, et al. Combined protein and transcript single-cell RNA sequencing in human peripheral blood mononuclear cells. Bmc Biology. 20: 193. PMID 36045343 DOI: 10.1186/s12915-022-01382-4  0.71
2022 Fan Z, Pitmon E, Wen L, Miller J, Ehinger E, Herro R, Liu W, Chen J, Mikulski Z, Conrad DJ, Marki A, Orecchioni M, Kumari P, Zhu YP, Marcovecchio PM, ... ... Ley K, et al. Bone Marrow Transplantation Rescues Monocyte Recruitment Defect and Improves Cystic Fibrosis in Mice. Journal of Immunology (Baltimore, Md. : 1950). 208: 745-752. PMID 35031577 DOI: 10.4049/jimmunol.1901171  0.716
2021 Winkels H, Ghosheh Y, Kobiyama K, Kiosses WB, Orecchioni M, Ehinger E, Suryawanshi V, Herrera-De La Mata S, Marchovecchio P, Riffelmacher T, Thiault N, Kronenberg M, Wolf D, Seumois G, Vijayanand P, ... Ley K, et al. Thymus-Derived CD4CD8 Cells Reside in Mediastinal Adipose Tissue and the Aortic Arch. Journal of Immunology (Baltimore, Md. : 1950). PMID 34740961 DOI: 10.4049/jimmunol.2100208  0.731
2021 Buscher K, Heitplatz B, Van Marck V, Song J, Loismann S, Rixen R, Hüchtmann B, Kurian S, Ehinger E, Wolf D, Ley K, Pavenstaedt H, Reuter S. Data Driven Kidney Transplant Phenotyping as a Histology-independent Framework for Biomarker Discovery. Journal of the American Society of Nephrology : Jasn. PMID 34078665 DOI: 10.1681/ASN.2020121685  0.683
2020 Dong Y, Lee Y, Cui K, He M, Wang B, Bhattacharjee S, Zhu B, Yago T, Zhang K, Deng L, Ouyang K, Wen A, Cowan DB, Song K, Yu L, ... ... Ley K, et al. Epsin-mediated degradation of IP3R1 fuels atherosclerosis. Nature Communications. 11: 3984. PMID 32770009 DOI: 10.1038/S41467-020-17848-4  0.36
2020 Wolf D, Gerhardt T, Winkels H, Anto Michel N, Pramod AB, Ghosheh Y, Brunel S, Buscher K, Miller J, McArdle S, Baas L, Kobiyama K, Vassallo M, Ehinger E, Dileepan T, ... ... Ley K, et al. Pathogenic Autoimmunity in Atherosclerosis Evolves from Initially Protective ApoB-Reactive CD4 T-Regulatory Cells. Circulation. PMID 32703007 DOI: 10.1161/Circulationaha.119.042863  0.729
2020 Ehinger E, Ghosheh Y, Pramod AB, Lin J, Hanna DB, Mueller K, Durant CP, Baas L, Qi Q, Wang T, Buscher K, Anastos K, Lazar JM, Mack WJ, Tien PC, ... ... Ley K, et al. Classical Monocyte Transcriptomes Reveal Significant Anti-Inflammatory Statin Effect in Women with Chronic HIV. Cardiovascular Research. PMID 32658258 DOI: 10.1093/Cvr/Cvaa188  0.71
2020 Marcovecchio PM, Zhu YP, Hanna RN, Dinh HQ, Tacke R, Wu R, McArdle S, Reynolds S, Araujo DJ, Ley K, Hedrick CC. Kindlin-3 is essential for patrolling and phagocytosis functions of nonclassical monocytes during metastatic cancer surveillance. Journal of Leukocyte Biology. PMID 32386455 DOI: 10.1002/Jlb.4Hi0420-098R  0.363
2020 Marki A, Ley K. Leaking chemokines confuse neutrophils. The Journal of Clinical Investigation. PMID 32202515 DOI: 10.1172/Jci136259  0.356
2019 Ramadass M, Johnson JL, Marki A, Zhang J, Wolf D, Kiosses WB, Pestonjamasp K, Ley K, Catz SD. The trafficking protein JFC1 regulates Rac1-GTP localization at the uropod controlling neutrophil chemotaxis and in vivo migration. Journal of Leukocyte Biology. PMID 30748033 DOI: 10.1002/Jlb.1Vma0818-320R  0.358
2018 Brophy ML, Dong Y, Tao H, Yancey PG, Song K, Zhang K, Wen A, Wu H, Lee Y, Malovichko MV, Sithu SD, Wong S, Yu L, Kocher O, Bischoff J, ... ... Ley K, et al. Myeloid-Specific Deletion of Epsins 1 and 2 Reduces Atherosclerosis by Preventing LRP-1 Downregulation. Circulation Research. PMID 30595089 DOI: 10.1161/Circresaha.118.313028  0.363
2018 Riopel M, Vassallo M, Ehinger E, Pattison J, Bowden K, Winkels H, Wilson M, de Jong R, Patel S, Balakrishna D, Bilakovics J, Fanjul A, Plonowski A, Larson CJ, Ley K, et al. CX3CL1-Fc treatment prevents atherosclerosis in Ldlr KO mice. Molecular Metabolism. PMID 30553772 DOI: 10.1016/J.Molmet.2018.11.011  0.758
2018 Mueller KAL, Hanna DB, Ehinger E, Xue X, Baas L, Gawaz MP, Geisler T, Anastos K, Cohen MH, Gange SJ, Heath SL, Lazar JM, Liu C, Mack WJ, Ofotokun I, ... ... Ley K, et al. Loss of CXCR4 on non-classical monocytes in participants of the Women's Interagency HIV Study (WIHS) with subclinical atherosclerosis. Cardiovascular Research. PMID 30520941 DOI: 10.1093/Cvr/Cvy292  0.713
2018 Winkels H, Ehinger E, Goshesh Y, Wolf D, Ley K. Atherosclerosis in the single-cell era. Current Opinion in Lipidology. PMID 30020199 DOI: 10.1097/Mol.0000000000000537  0.722
2018 Que X, Hung MY, Yeang C, Gonen A, Prohaska TA, Sun X, Diehl C, Määttä A, Gaddis DE, Bowden K, Pattison J, MacDonald JG, Ylä-Herttuala S, Mellon PL, Hedrick CC, ... Ley K, et al. Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice. Nature. PMID 29875409 DOI: 10.1038/S41586-018-0198-8  0.352
2018 Winkels H, Ehinger E, Vassallo M, Buscher K, Dinh H, Kobiyama K, Hamers A, Cochain C, Vafadarnejad E, Saliba AE, Zernecke A, Pramod A, Ghosh A, Anto Michel N, Hoppe N, ... ... Ley K, et al. Atlas of the Immune Cell Repertoire in Mouse Atherosclerosis Defined by Single-Cell RNA-Sequencing and Mass Cytometry. Circulation Research. PMID 29545366 DOI: 10.1161/Circresaha.117.312513  0.739
2018 Cochain C, Vafadarnejad E, Arampatzi P, Jaroslav P, Winkels H, Ley K, Wolf D, Saliba AE, Zernecke A. Single-Cell RNA-Seq Reveals the Transcriptional Landscape and Heterogeneity of Aortic Macrophages in Murine Atherosclerosis. Circulation Research. PMID 29545365 DOI: 10.1161/Circresaha.117.312509  0.355
2018 Wolf D, Anto-Michel N, Blankenbach H, Wiedemann A, Buscher K, Hohmann JD, Lim B, Bäuml M, Marki A, Mauler M, Duerschmied D, Fan Z, Winkels H, Sidler D, Diehl P, ... ... Ley K, et al. A ligand-specific blockade of the integrin Mac-1 selectively targets pathologic inflammation while maintaining protective host-defense. Nature Communications. 9: 525. PMID 29410422 DOI: 10.1038/S41467-018-02896-8  0.323
2018 Anto Michel N, Colberg C, Buscher K, Sommer B, Pramod AB, Ehinger E, Dufner B, Hoppe N, Pfeiffer K, Marchini T, Willecke F, Stachon P, Hilgendorf I, Heidt T, von Zur Mühlen C, ... ... Ley K, et al. Inflammatory Pathways Regulated By Tumor-Necrosis Receptor Associated Factor 1 Protect From Metabolic Consequences In Diet-Induced Obesity. Circulation Research. PMID 29358227 DOI: 10.1161/Circresaha.117.312055  0.739
2018 Winkels H, Ley K. Natural Killer Cells at Ease: Atherosclerosis Is Not Affected by Genetic Depletion or Hyperactivation of Natural Killer Cells. Circulation Research. 122: 6-7. PMID 29301835 DOI: 10.1161/Circresaha.117.312289  0.351
2018 Ehinger E, Akula Bala P, Lin J, Hanna DB, Mueller K, Baas L, Qi Q, Wang T, Buscher K, Liu Y, Anastos K, Lazar JM, Mack WJ, Tien PC, Cohen MH, ... ... Ley K, et al. Abstract 410: Statin Use May Alleviate Coagulation- and Inflammation-associated Gene Expression in Circulating Classical Monocytes in Women With Chronic HIV-1 Infection Arteriosclerosis, Thrombosis, and Vascular Biology. 38. DOI: 10.1161/Atvb.38.Suppl_1.410  0.718
2018 Wolf D, Michel NA, Buscher K, Ley K, Libby P, Bode C, Peter K, Zirlik A. Abstract 031: A Ligand-specific Blockade of the Integrin Mac-1 Selectively Targets Pathologic Vascular Inflammation While Maintaining Protective Host-defense Arteriosclerosis, Thrombosis, and Vascular Biology. 38. DOI: 10.1161/Atvb.38.Suppl_1.031  0.36
2018 Winkels H, Ehinger E, Vassalo M, Buscher K, Dinh H, Kobiyama K, Hamers A, Cochain C, Vafadarnejad E, Saliba AE, Zernecke A, Bala PA, Ghosh AK, Michel NA, Hoppe N, ... ... Ley K, et al. Abstract 004: Comprehensive Assessment of Immune Cells in Mouse and Human Atherosclerosis by Single-cell RNA-sequencing and Mass Cytometry Arteriosclerosis, Thrombosis, and Vascular Biology. 38. DOI: 10.1161/Atvb.38.Suppl_1.004  0.73
2017 Buscher K, Marcovecchio P, Hedrick CC, Ley K. Patrolling Mechanics of Non-Classical Monocytes in Vascular Inflammation. Frontiers in Cardiovascular Medicine. 4: 80. PMID 29312957 DOI: 10.3389/Fcvm.2017.00080  0.324
2017 Marcovecchio PM, Thomas GD, Mikulski Z, Ehinger E, Mueller KAL, Blatchley A, Wu R, Miller YI, Nguyen AT, Taylor AM, McNamara CA, Ley K, Hedrick CC. Scavenger Receptor CD36 Directs Nonclassical Monocyte Patrolling Along the Endothelium During Early Atherogenesis. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 28935758 DOI: 10.1161/Atvbaha.117.309123  0.725
2017 Marki A, Buscher K, Mikulski Z, Pries A, Ley K. Rolling neutrophils form tethers and slings under physiologic conditions in vivo. Journal of Leukocyte Biology. PMID 28821572 DOI: 10.1189/Jlb.1Ab0617-230R  0.351
2017 Buscher K, Ehinger E, Gupta P, Pramod AB, Wolf D, Tweet G, Pan C, Mills CD, Lusis AJ, Ley K. Natural variation of macrophage activation as disease-relevant phenotype predictive of inflammation and cancer survival. Nature Communications. 8: 16041. PMID 28737175 DOI: 10.1038/Ncomms16041  0.735
2017 Peshkova IO, Fatkhullina AR, Mikulski Z, Ley K, Koltsova EK. IL-27R signaling controls myeloid cells accumulation and antigen-presentation in atherosclerosis. Scientific Reports. 7: 2255. PMID 28536468 DOI: 10.1038/S41598-017-01828-8  0.366
2017 Thiriot A, Perdomo C, Cheng G, Novitzky-Basso I, McArdle S, Kishimoto JK, Barreiro O, Mazo I, Triboulet R, Ley K, Rot A, von Andrian UH. Differential DARC/ACKR1 expression distinguishes venular from non-venular endothelial cells in murine tissues. Bmc Biology. 15: 45. PMID 28526034 DOI: 10.1186/S12915-017-0381-7  0.35
2017 Ley K, Gerdes N, Winkels H. ATVB Distinguished Scientist Award: How Costimulatory and Coinhibitory Pathways Shape Atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 28360089 DOI: 10.1161/Atvbaha.117.308611  0.324
2017 Quintar A, McArdle S, Wolf D, Marki A, Ehinger E, Vassallo M, Miller JF, Mikulski Z, Ley K, Buscher K. Endothelial Protective Monocyte Patrolling in Large Arteries Intensified by Western Diet and Atherosclerosis. Circulation Research. PMID 28302649 DOI: 10.1161/Circresaha.117.310739  0.794
2017 Abadier M, Ley K. P-selectin glycoprotein ligand-1 in T cells. Current Opinion in Hematology. PMID 28178038 DOI: 10.1097/Moh.0000000000000331  0.328
2017 Kimura T, Tse K, McArdle S, Gerhardt T, Miller J, Mikulski Z, Sidney J, Sette A, Wolf D, Ley K. Atheroprotective vaccination with MHC-II-restricted ApoB peptides induces peritoneal IL-10-producing CD4 T cells. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00798.2016. PMID 28087520 DOI: 10.1152/Ajpheart.00798.2016  0.304
2016 McArdle S, Mikulski Z, Ley K. Live cell imaging to understand monocyte, macrophage, and dendritic cell function in atherosclerosis. The Journal of Experimental Medicine. PMID 27270892 DOI: 10.1084/Jem.20151885  0.305
2016 Fan Z, Ley K. Leukocyte Adhesion Deficiency IV. Monocyte Integrin Activation Deficiency in Cystic Fibrosis. American Journal of Respiratory and Critical Care Medicine. 193: 1075-7. PMID 27174474 DOI: 10.1164/Rccm.201512-2454Ed  0.322
2016 Buscher K, Wang H, Zhang X, Striewski P, Wirth B, Saggu G, Lütke-Enking S, Mayadas TN, Ley K, Sorokin L, Song J. Protection from septic peritonitis by rapid neutrophil recruitment through omental high endothelial venules. Nature Communications. 7: 10828. PMID 26940548 DOI: 10.1038/Ncomms10828  0.35
2016 Ley K, Rivera-Nieves J, Sandborn WJ, Shattil S. Integrin-based therapeutics: biological basis, clinical use and new drugs. Nature Reviews. Drug Discovery. 15: 173-83. PMID 26822833 DOI: 10.1038/Nrd.2015.10  0.315
2016 Ley K. 2015 Russell Ross Memorial Lecture in Vascular Biology: Protective Autoimmunity in Atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 36: 429-38. PMID 26821946 DOI: 10.1161/Atvbaha.115.306009  0.308
2016 Mikulski Z, Ley K. P-150 CCL21 Defect in Ileitis-Prone SAMP1/YitFc Mice Inflammatory Bowel Diseases. 22: S56. DOI: 10.1097/01.Mib.0000480246.10020.6D  0.305
2015 Côte M, Fos C, Canonigo-Balancio AJ, Ley K, Bécart S, Altman A. SLAT promotes TCR-mediated, Rap1-dependent LFA-1 activation and adhesion through interaction of its PH domain with Rap1. Journal of Cell Science. 128: 4341-52. PMID 26483383 DOI: 10.1242/Jcs.172742  0.317
2015 Block H, Stadtmann A, Riad D, Rossaint J, Sohlbach C, Germena G, Wu D, Simon SI, Ley K, Zarbock A. Gnb isoforms orchestrate a signaling pathway comprising Rac1 and Plcβ2/3 leading to LFA-1 activation and neutrophil arrest in vivo. Blood. PMID 26468229 DOI: 10.1182/Blood-2015-06-651034  0.353
2015 Wolf D, Zirlik A, Ley K. Beyond vascular inflammation--recent advances in understanding atherosclerosis. Cellular and Molecular Life Sciences : Cmls. 72: 3853-69. PMID 26100516 DOI: 10.1007/S00018-015-1971-6  0.362
2015 Gerhardt T, Ley K. Monocyte trafficking across the vessel wall. Cardiovascular Research. 107: 321-30. PMID 25990461 DOI: 10.1093/Cvr/Cvv147  0.367
2015 Marki A, Esko JD, Pries AR, Ley K. Role of the endothelial surface layer in neutrophil recruitment. Journal of Leukocyte Biology. 98: 503-15. PMID 25979432 DOI: 10.1189/Jlb.3Mr0115-011R  0.346
2015 Quintar AA, Hedrick CC, Ley K. Monocyte phenotypes: when local education counts. The Journal of Experimental Medicine. 212: 432. PMID 25847970 DOI: 10.1084/Jem.2124Insight1  0.706
2015 Mills CD, Lenz LL, Ley K. Macrophages at the fork in the road to health or disease. Frontiers in Immunology. 6: 59. PMID 25762997 DOI: 10.3389/Fimmu.2015.00059  0.309
2015 McArdle S, Chodaczek G, Ray N, Ley K. Intravital live cell triggered imaging system reveals monocyte patrolling and macrophage migration in atherosclerotic arteries. Journal of Biomedical Optics. 20: 26005. PMID 25710308 DOI: 10.1117/1.Jbo.20.2.026005  0.332
2015 Wolf D, Ley K. Waking up the stem cell niche: how hematopoietic stem cells generate inflammatory monocytes after stroke. Circulation Research. 116: 389-92. PMID 25634966 DOI: 10.1161/Circresaha.114.305678  0.306
2015 Mikulski Z, Johnson R, Shaked I, Kim G, Nowyhed H, Goodman W, Chodaczek G, Pizarro TT, Cominelli F, Ley K. SAMP1/YitFc mice develop ileitis via loss of CCL21 and defects in dendritic cell migration. Gastroenterology. 148: 783-793.e5. PMID 25620669 DOI: 10.1053/J.Gastro.2015.01.027  0.334
2015 Li J, Ley K. Lymphocyte migration into atherosclerotic plaque. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 40-9. PMID 25301842 DOI: 10.1161/Atvbaha.114.303227  0.341
2014 Mills CD, Ley K. M1 and M2 macrophages: the chicken and the egg of immunity. Journal of Innate Immunity. 6: 716-26. PMID 25138714 DOI: 10.1159/000364945  0.303
2014 Koltsova EK, Sundd P, Zarpellon A, Ouyang H, Mikulski Z, Zampolli A, Ruggeri ZM, Ley K. Genetic deletion of platelet glycoprotein Ib alpha but not its extracellular domain protects from atherosclerosis. Thrombosis and Haemostasis. 112: 1252-63. PMID 25104056 DOI: 10.1160/Th14-02-0130  0.371
2014 Gjurich BN, Taghavie-Moghadam PL, Ley K, Galkina EV. L-selectin deficiency decreases aortic B1a and Breg subsets and promotes atherosclerosis. Thrombosis and Haemostasis. 112: 803-11. PMID 24989887 DOI: 10.1160/Th13-10-0865  0.359
2013 Tse K, Tse H, Sidney J, Sette A, Ley K. T cells in atherosclerosis. International Immunology. 25: 615-22. PMID 24154816 DOI: 10.1093/Intimm/Dxt043  0.329
2013 Stadtmann A, Germena G, Block H, Boras M, Rossaint J, Sundd P, Lefort C, Fisher CI, Buscher K, Gelschefarth B, Urzainqui A, Gerke V, Ley K, Zarbock A. The PSGL-1-L-selectin signaling complex regulates neutrophil adhesion under flow. The Journal of Experimental Medicine. 210: 2171-80. PMID 24127491 DOI: 10.1084/Jem.20130664  0.309
2013 Ley K. Leukocytes talking to VE-cadherin. Blood. 122: 2300-1. PMID 24092927 DOI: 10.1182/Blood-2013-08-519918  0.304
2013 Koltsova EK, Hedrick CC, Ley K. Myeloid cells in atherosclerosis: a delicate balance of anti-inflammatory and proinflammatory mechanisms. Current Opinion in Lipidology. 24: 371-80. PMID 24005215 DOI: 10.1097/Mol.0B013E328363D298  0.373
2013 Sundd P, Pospieszalska MK, Ley K. Neutrophil rolling at high shear: flattening, catch bond behavior, tethers and slings. Molecular Immunology. 55: 59-69. PMID 23141302 DOI: 10.1016/J.Molimm.2012.10.025  0.324
2013 Tse K, Ley K. Transforming growth factor-β: transforming plaque to stability. European Heart Journal. 34: 3684-6. PMID 22843445 DOI: 10.1093/Eurheartj/Ehs228  0.341
2012 Spann NJ, Garmire LX, McDonald JG, Myers DS, Milne SB, Shibata N, Reichart D, Fox JN, Shaked I, Heudobler D, Raetz CR, Wang EW, Kelly SL, Sullards MC, Murphy RC, ... ... Ley K, et al. Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses. Cell. 151: 138-52. PMID 23021221 DOI: 10.1016/J.Cell.2012.06.054  0.367
2012 Koltsova EK, Garcia Z, Chodaczek G, Landau M, McArdle S, Scott SR, von Vietinghoff S, Galkina E, Miller YI, Acton ST, Ley K. Dynamic T cell-APC interactions sustain chronic inflammation in atherosclerosis. The Journal of Clinical Investigation. 122: 3114-26. PMID 22886300 DOI: 10.1172/Jci61758  0.387
2012 Axelsson J, Xu D, Kang BN, Nussbacher JK, Handel TM, Ley K, Sriramarao P, Esko JD. Inactivation of heparan sulfate 2-O-sulfotransferase accentuates neutrophil infiltration during acute inflammation in mice. Blood. 120: 1742-51. PMID 22791291 DOI: 10.1182/Blood-2012-03-417139  0.377
2012 Sundd P, Gutierrez E, Koltsova EK, Kuwano Y, Fukuda S, Pospieszalska MK, Groisman A, Ley K. 'Slings' enable neutrophil rolling at high shear. Nature. 488: 399-403. PMID 22763437 DOI: 10.1038/Nature11248  0.335
2012 Lefort CT, Ley K. Neutrophil arrest by LFA-1 activation. Frontiers in Immunology. 3: 157. PMID 22701459 DOI: 10.3389/Fimmu.2012.00157  0.337
2012 Shaked I, Ley K. Protective role for myeloid specific KLF2 in atherosclerosis. Circulation Research. 110: 1266. PMID 22581916 DOI: 10.1161/Circresaha.112.270991  0.392
2012 Block H, Ley K, Zarbock A. Severe impairment of leukocyte recruitment in ppGalNAcT-1-deficient mice. Journal of Immunology (Baltimore, Md. : 1950). 188: 5674-81. PMID 22544932 DOI: 10.4049/Jimmunol.1200392  0.363
2012 Lefort CT, Rossaint J, Moser M, Petrich BG, Zarbock A, Monkley SJ, Critchley DR, Ginsberg MH, Fässler R, Ley K. Distinct roles for talin-1 and kindlin-3 in LFA-1 extension and affinity regulation. Blood. 119: 4275-82. PMID 22431571 DOI: 10.1182/Blood-2011-08-373118  0.358
2012 Bertram A, Zhang H, von Vietinghoff S, de Pablo C, Haller H, Shushakova N, Ley K. Protein kinase C-θ is required for murine neutrophil recruitment and adhesion strengthening under flow. Journal of Immunology (Baltimore, Md. : 1950). 188: 4043-51. PMID 22403440 DOI: 10.4049/Jimmunol.1101651  0.383
2012 Wingender G, Hiss M, Engel I, Peukert K, Ley K, Haller H, Kronenberg M, von Vietinghoff S. Neutrophilic granulocytes modulate invariant NKT cell function in mice and humans. Journal of Immunology (Baltimore, Md. : 1950). 188: 3000-8. PMID 22387552 DOI: 10.4049/Jimmunol.1101273  0.389
2012 Hanna RN, Shaked I, Hubbeling HG, Punt JA, Wu R, Herrley E, Zaugg C, Pei H, Geissmann F, Ley K, Hedrick CC. NR4A1 (Nur77) deletion polarizes macrophages toward an inflammatory phenotype and increases atherosclerosis. Circulation Research. 110: 416-27. PMID 22194622 DOI: 10.1161/Circresaha.111.253377  0.31
2012 Doran AC, Lipinski MJ, Oldham SN, Garmey JC, Campbell KA, Skaflen MD, Cutchins A, Lee DJ, Glover DK, Kelly KA, Galkina EV, Ley K, Witztum JL, Tsimikas S, Bender TP, et al. B-cell aortic homing and atheroprotection depend on Id3. Circulation Research. 110: e1-12. PMID 22034493 DOI: 10.1161/Circresaha.111.256438  0.319
2012 Lefort CT, Rossaint J, Moser M, Petrich BG, Zarbock A, Monkley SJ, Critchley DR, Ginsberg MH, Fässler R, Ley K. Distinct Roles for Talin-1 and Kindlin-3 in Regulating LFA-1 Conformation during Neutrophil Rolling and Arrest Biophysical Journal. 102: 347a. DOI: 10.1016/J.Bpj.2011.11.1900  0.322
2012 Sundd P, Gutierrez E, Pospieszalska MK, Koltsova E, Kuwano Y, Fukuda S, Groisman A, Ley K. Neutrophil Sling: a New Cell-Autonomous Adhesive Structure Enabling Rolling at High Shear Stress Biophysical Journal. 102: 194a-195a. DOI: 10.1016/J.Bpj.2011.11.1061  0.327
2011 Zarbock A, Ley K, McEver RP, Hidalgo A. Leukocyte ligands for endothelial selectins: specialized glycoconjugates that mediate rolling and signaling under flow. Blood. 118: 6743-51. PMID 22021370 DOI: 10.1182/Blood-2011-07-343566  0.34
2011 Ley K. CD63 positions CD62P for rolling. Blood. 118: 4012-3. PMID 21998333 DOI: 10.1182/Blood-2011-08-372318  0.309
2011 Maiguel D, Faridi MH, Wei C, Kuwano Y, Balla KM, Hernandez D, Barth CJ, Lugo G, Donnelly M, Nayer A, Moita LF, Schürer S, Traver D, Ruiz P, Vazquez-Padron RI, ... Ley K, et al. Small molecule-mediated activation of the integrin CD11b/CD18 reduces inflammatory disease. Science Signaling. 4: ra57. PMID 21900205 DOI: 10.1126/Scisignal.2001811  0.347
2011 Koltsova EK, Ley K. How dendritic cells shape atherosclerosis. Trends in Immunology. 32: 540-7. PMID 21835696 DOI: 10.1016/J.It.2011.07.001  0.309
2011 Butcher MJ, Herre M, Ley K, Galkina E. Flow cytometry analysis of immune cells within murine aortas. Journal of Visualized Experiments : Jove. PMID 21750492 DOI: 10.3791/2848  0.361
2011 Ley K, Miller YI, Hedrick CC. Monocyte and macrophage dynamics during atherogenesis. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 1506-16. PMID 21677293 DOI: 10.1161/Atvbaha.110.221127  0.391
2011 Tang J, Zarbock A, Gomez I, Wilson CL, Lefort CT, Stadtmann A, Bell B, Huang LC, Ley K, Raines EW. Adam17-dependent shedding limits early neutrophil influx but does not alter early monocyte recruitment to inflammatory sites. Blood. 118: 786-94. PMID 21628404 DOI: 10.1182/Blood-2010-11-321406  0.352
2011 von Vietinghoff S, Koltsova EK, Mestas J, Diehl CJ, Witztum JL, Ley K. Mycophenolate mofetil decreases atherosclerotic lesion size by depression of aortic T-lymphocyte and interleukin-17-mediated macrophage accumulation. Journal of the American College of Cardiology. 57: 2194-204. PMID 21596236 DOI: 10.1016/J.Jacc.2010.12.030  0.326
2011 Stadtmann A, Brinkhaus L, Mueller H, Rossaint J, Bolomini-Vittori M, Bergmeier W, Van Aken H, Wagner DD, Laudanna C, Ley K, Zarbock A. Rap1a activation by CalDAG-GEFI and p38 MAPK is involved in E-selectin-dependent slow leukocyte rolling. European Journal of Immunology. 41: 2074-85. PMID 21480213 DOI: 10.1002/Eji.201041196  0.355
2011 Sundd P, Gutierrez E, Petrich BG, Ginsberg MH, Groisman A, Ley K. Live cell imaging of paxillin in rolling neutrophils by dual-color quantitative dynamic footprinting. Microcirculation (New York, N.Y. : 1994). 18: 361-72. PMID 21418380 DOI: 10.1111/J.1549-8719.2011.00090.X  0.308
2011 Zarbock A, Ley K. Protein tyrosine kinases in neutrophil activation and recruitment. Archives of Biochemistry and Biophysics. 510: 112-9. PMID 21338576 DOI: 10.1016/J.Abb.2011.02.009  0.322
2011 Morris MA, McDuffie M, Nadler JL, Ley K. Prevention, but not cure, of autoimmune diabetes in a NOD.scid transfer model by FTY720 despite effective modulation of blood T cells. Autoimmunity. 44: 115-28. PMID 20695767 DOI: 10.3109/08916934.2010.499885  0.336
2011 Ley K. The Microcirculation in Inflammation Comprehensive Physiology. 387-448. DOI: 10.1002/Cphy.Cp020409  0.366
2010 von Vietinghoff S, Ley K. Interleukin 17 in vascular inflammation. Cytokine & Growth Factor Reviews. 21: 463-9. PMID 21075042 DOI: 10.1016/J.Cytogfr.2010.10.003  0.32
2010 Little KM, Smalley DM, Harthun NL, Ley K. The plasma microparticle proteome. Seminars in Thrombosis and Hemostasis. 36: 845-56. PMID 21049385 DOI: 10.1055/S-0030-1267038  0.759
2010 Gorfu G, Rivera-Nieves J, Hoang S, Abbott DW, Arbenz-Smith K, Azar DW, Pizarro TT, Cominelli F, McDuffie M, Ley K. Beta7 integrin deficiency suppresses B cell homing and attenuates chronic ileitis in SAMP1/YitFc mice. Journal of Immunology (Baltimore, Md. : 1950). 185: 5561-8. PMID 20926792 DOI: 10.4049/Jimmunol.0903938  0.352
2010 Sundd P, Gutierrez E, Pospieszalska MK, Zhang H, Groisman A, Ley K. Quantitative dynamic footprinting microscopy reveals mechanisms of neutrophil rolling. Nature Methods. 7: 821-4. PMID 20871617 DOI: 10.1038/Nmeth.1508  0.321
2010 Anderson CR, Rychak JJ, Backer M, Backer J, Ley K, Klibanov AL. scVEGF microbubble ultrasound contrast agents: a novel probe for ultrasound molecular imaging of tumor angiogenesis. Investigative Radiology. 45: 579-85. PMID 20733505 DOI: 10.1097/Rli.0B013E3181Efd581  0.667
2010 Koltsova EK, Ley K. The mysterious ways of the chemokine CXCL5. Immunity. 33: 7-9. PMID 20643334 DOI: 10.1016/J.Immuni.2010.07.012  0.321
2010 von Vietinghoff S, Asagiri M, Azar D, Hoffmann A, Ley K. Defective regulation of CXCR2 facilitates neutrophil release from bone marrow causing spontaneous inflammation in severely NF-kappa B-deficient mice. Journal of Immunology (Baltimore, Md. : 1950). 185: 670-8. PMID 20519647 DOI: 10.4049/Jimmunol.1000339  0.35
2010 Kuwano Y, Spelten O, Zhang H, Ley K, Zarbock A. Rolling on E- or P-selectin induces the extended but not high-affinity conformation of LFA-1 in neutrophils. Blood. 116: 617-24. PMID 20445017 DOI: 10.1182/Blood-2010-01-266122  0.311
2010 von Vietinghoff S, Ouyang H, Ley K. Mycophenolic acid suppresses granulopoiesis by inhibition of interleukin-17 production. Kidney International. 78: 79-88. PMID 20375992 DOI: 10.1038/Ki.2010.84  0.309
2010 Smith E, Prasad KMR, Butcher M, Dobrian A, Kolls JK, Ley K, Galkina E. Blockade of interleukin-17A results in reduced atherosclerosis in apolipoprotein E-deficient mice Circulation. 121: 1746-1755. PMID 20368519 DOI: 10.1161/Circulationaha.109.924886  0.312
2010 Gleissner CA, Shaked I, Little KM, Ley K. CXC chemokine ligand 4 induces a unique transcriptome in monocyte-derived macrophages. Journal of Immunology (Baltimore, Md. : 1950). 184: 4810-8. PMID 20335529 DOI: 10.4049/Jimmunol.0901368  0.774
2010 Buscher K, Riese SB, Shakibaei M, Reich C, Dernedde J, Tauber R, Ley K. The transmembrane domains of L-selectin and CD44 regulate receptor cell surface positioning and leukocyte adhesion under flow. The Journal of Biological Chemistry. 285: 13490-7. PMID 20212041 DOI: 10.1074/Jbc.M110.102640  0.308
2010 Mueller H, Stadtmann A, Van Aken H, Hirsch E, Wang D, Ley K, Zarbock A. Tyrosine kinase Btk regulates E-selectin-mediated integrin activation and neutrophil recruitment by controlling phospholipase C (PLC) gamma2 and PI3Kgamma pathways. Blood. 115: 3118-27. PMID 20167705 DOI: 10.1182/Blood-2009-11-254185  0.304
2010 Little KM, Lee JK, Ley K. ReSASC: a resampling-based algorithm to determine differential protein expression from spectral count data. Proteomics. 10: 1212-22. PMID 20058246 DOI: 10.1002/Pmic.200900328  0.758
2010 Gleissner CA, Shaked I, Erbel C, Böckler D, Katus HA, Ley K. CXCL4 downregulates the atheroprotective hemoglobin receptor CD163 in human macrophages. Circulation Research. 106: 203-11. PMID 19910578 DOI: 10.1161/Circresaha.109.199505  0.345
2010 Harthun NL, Smalley DM, Little KM, Ley K. Proteomic Analysis of Microparticles from Patients with Abdominal Aortic Aneurysms Journal of Vascular Surgery. 52: 1743. DOI: 10.1016/J.Jvs.2010.10.027  0.743
2010 Sundd P, Gutierrez E, Pospieszalska M, Groisman A, Ley K. Stressed and Compressed Molecular Bonds Revealed in Footprints of Rolling Neutrophils using Total Internal Reflection Fluorescence Microscopy Biophysical Journal. 98: 595a. DOI: 10.1016/J.Bpj.2009.12.3236  0.339
2009 Pospieszalska MK, Ley K. Dynamics of Microvillus Extension and Tether Formation in Rolling Leukocytes. Cellular and Molecular Bioengineering. 2: 207-217. PMID 20046963 DOI: 10.1007/S12195-009-0063-9  0.309
2009 Gorfu G, Rivera-Nieves J, Ley K. Role of β7 integrins in intestinal lymphocyte homing and retention Current Molecular Medicine. 9: 836-850. PMID 19860663 DOI: 10.2174/156652409789105525  0.334
2009 Koltsova E, Ley K. Tyrosine sulfation of leukocyte adhesion molecules and chemokine receptors promotes atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 1709-11. PMID 19846834 DOI: 10.1161/Atvbaha.109.195552  0.383
2009 Smith E, von Vietinghoff S, Stark MA, Zarbock A, Sanders JM, Duley A, Rivera-Nieves J, Bender TP, Ley K. T-lineage cells require the thymus but not VDJ recombination to produce IL-17A and regulate granulopoiesis in vivo. Journal of Immunology (Baltimore, Md. : 1950). 183: 5685-93. PMID 19843951 DOI: 10.4049/Jimmunol.0900887  0.726
2009 Reutershan J, Saprito MS, Wu D, Rückle T, Ley K. Phosphoinositide 3-kinase gamma required for lipopolysaccharide-induced transepithelial neutrophil trafficking in the lung. The European Respiratory Journal. 35: 1137-47. PMID 19797129 DOI: 10.1183/09031936.00085509  0.342
2009 DiStasi MR, Ley K. Opening the flood-gates: how neutrophil-endothelial interactions regulate permeability. Trends in Immunology. 30: 547-56. PMID 19783480 DOI: 10.1016/J.It.2009.07.012  0.332
2009 Zarbock A, Distasi MR, Smith E, Sanders JM, Kronke G, Harry BL, von Vietinghoff S, Buscher K, Nadler JL, Ley K. Improved survival and reduced vascular permeability by eliminating or blocking 12/15-lipoxygenase in mouse models of acute lung injury (ALI). Journal of Immunology (Baltimore, Md. : 1950). 183: 4715-22. PMID 19752233 DOI: 10.4049/Jimmunol.0802592  0.323
2009 Zarbock A, Müller H, Kuwano Y, Ley K. PSGL-1-dependent myeloid leukocyte activation. Journal of Leukocyte Biology. 86: 1119-24. PMID 19703898 DOI: 10.1189/Jlb.0209117  0.354
2009 Ferrante EA, Pickard JE, Rychak J, Klibanov A, Ley K. Dual targeting improves microbubble contrast agent adhesion to VCAM-1 and P-selectin under flow. Journal of Controlled Release : Official Journal of the Controlled Release Society. 140: 100-7. PMID 19666063 DOI: 10.1016/J.Jconrel.2009.08.001  0.691
2009 Sperandio M, Gleissner CA, Ley K. Glycosylation in immune cell trafficking. Immunological Reviews. 230: 97-113. PMID 19594631 DOI: 10.1111/J.1600-065X.2009.00795.X  0.352
2009 Zarbock A, Ley K. New insights into leukocyte recruitment by intravital microscopy. Current Topics in Microbiology and Immunology. 334: 129-52. PMID 19521684 DOI: 10.1007/978-3-540-93864-4_6  0.331
2009 Reutershan J, Harry B, Chang D, Bagby GJ, Ley K. DARC on RBC limits lung injury by balancing compartmental distribution of CXC chemokines. European Journal of Immunology. 39: 1597-607. PMID 19499525 DOI: 10.1002/Eji.200839089  0.382
2009 Ley K. Cell adhesion under flow. Microcirculation (New York, N.Y. : 1994). 16: 1-2. PMID 19191171 DOI: 10.1080/10739680802644415  0.348
2009 Zarbock A, Ley K. Neutrophil adhesion and activation under flow. Microcirculation (New York, N.Y. : 1994). 16: 31-42. PMID 19037827 DOI: 10.1080/10739680802350104  0.354
2009 Rivera-Nieves J, Gorfu G, Ley K. Leukocyte adhesion molecules in animal models of inflammatory bowel disease. Inflammatory Bowel Diseases. 14: 1715-35. PMID 18523998 DOI: 10.1002/Ibd.20501  0.337
2008 Mestas J, Ley K. Monocyte-endothelial cell interactions in the development of atherosclerosis. Trends in Cardiovascular Medicine. 18: 228-32. PMID 19185814 DOI: 10.1016/J.Tcm.2008.11.004  0.369
2008 Ley K, Zhang H. Dances with leukocytes: how tetraspanin-enriched microdomains assemble to form endothelial adhesive platforms. The Journal of Cell Biology. 183: 375-6. PMID 18981226 DOI: 10.1083/Jcb.200809173  0.334
2008 von Vietinghoff S, Ley K. Homeostatic regulation of blood neutrophil counts. Journal of Immunology (Baltimore, Md. : 1950). 181: 5183-8. PMID 18832668 DOI: 10.4049/Jimmunol.181.8.5183  0.319
2008 Zarbock A, Abram CL, Hundt M, Altman A, Lowell CA, Ley K. PSGL-1 engagement by E-selectin signals through Src kinase Fgr and ITAM adapters DAP12 and FcR gamma to induce slow leukocyte rolling. The Journal of Experimental Medicine. 205: 2339-47. PMID 18794338 DOI: 10.1084/Jem.20072660  0.344
2008 Gleissner CA, von Hundelshausen P, Ley K. Platelet chemokines in vascular disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 1920-7. PMID 18723831 DOI: 10.1161/Atvbaha.108.169417  0.363
2008 Harry BL, Sanders JM, Feaver RE, Lansey M, Deem TL, Zarbock A, Bruce AC, Pryor AW, Gelfand BD, Blackman BR, Schwartz MA, Ley K. Endothelial cell PECAM-1 promotes atherosclerotic lesions in areas of disturbed flow in ApoE-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 2003-8. PMID 18688018 DOI: 10.1161/Atvbaha.108.164707  0.389
2008 Smith E, Stark MA, Zarbock A, Burcin TL, Bruce AC, Vaswani D, Foley P, Ley K. IL-17A inhibits the expansion of IL-17A-producing T cells in mice through "short-loop" inhibition via IL-17 receptor. Journal of Immunology (Baltimore, Md. : 1950). 181: 1357-64. PMID 18606690 DOI: 10.4049/Jimmunol.181.2.1357  0.712
2008 Frommhold D, Ludwig A, Bixel MG, Zarbock A, Babushkina I, Weissinger M, Cauwenberghs S, Ellies LG, Marth JD, Beck-Sickinger AG, Sixt M, Lange-Sperandio B, Zernecke A, Brandt E, Weber C, ... ... Ley K, et al. Sialyltransferase ST3Gal-IV controls CXCR2-mediated firm leukocyte arrest during inflammation. The Journal of Experimental Medicine. 205: 1435-46. PMID 18519646 DOI: 10.1084/Jem.20070846  0.366
2008 Alon R, Ley K. Cells on the run: shear-regulated integrin activation in leukocyte rolling and arrest on endothelial cells. Current Opinion in Cell Biology. 20: 525-32. PMID 18499427 DOI: 10.1016/J.Ceb.2008.04.003  0.347
2008 Galkina E, Ley K. Leukocyte influx in atherosclerosis. Current Drug Targets. 8: 1239-48. PMID 18220701 DOI: 10.2174/138945007783220650  0.396
2008 Gleissner CA, Ley K. CXCL4 in atherosclerosis: possible roles in monocyte arrest and macrophage foam cell formation. Thrombosis and Haemostasis. 98: 917-8. PMID 18000592 DOI: 10.1160/Th07-09-0567  0.353
2007 Zarbock A, Ley K. Mechanisms and consequences of neutrophil interaction with the endothelium. The American Journal of Pathology. 172: 1-7. PMID 18079440 DOI: 10.2353/Ajpath.2008.070502  0.35
2007 Smith E, Zarbock A, Stark MA, Burcin TL, Bruce AC, Foley P, Ley K. IL-23 is required for neutrophil homeostasis in normal and neutrophilic mice. Journal of Immunology (Baltimore, Md. : 1950). 179: 8274-9. PMID 18056371 DOI: 10.4049/Jimmunol.179.12.8274  0.725
2007 Tenno M, Ohtsubo K, Hagen FK, Ditto D, Zarbock A, Schaerli P, von Andrian UH, Ley K, Le D, Tabak LA, Marth JD. Initiation of protein O glycosylation by the polypeptide GalNAcT-1 in vascular biology and humoral immunity. Molecular and Cellular Biology. 27: 8783-96. PMID 17923703 DOI: 10.1128/Mcb.01204-07  0.339
2007 Galkina E, Harry BL, Ludwig A, Liehn EA, Sanders JM, Bruce A, Weber C, Ley K. CXCR6 promotes atherosclerosis by supporting T-cell homing, interferon-gamma production, and macrophage accumulation in the aortic wall. Circulation. 116: 1801-11. PMID 17909108 DOI: 10.1161/Circulationaha.106.678474  0.326
2007 Zarbock A, Deem TL, Burcin TL, Ley K. Galphai2 is required for chemokine-induced neutrophil arrest. Blood. 110: 3773-9. PMID 17699741 DOI: 10.1182/Blood-2007-06-094565  0.393
2007 Reutershan J, Cagnina RE, Chang D, Linden J, Ley K. Therapeutic anti-inflammatory effects of myeloid cell adenosine receptor A2a stimulation in lipopolysaccharide-induced lung injury. Journal of Immunology (Baltimore, Md. : 1950). 179: 1254-63. PMID 17617618 DOI: 10.4049/Jimmunol.179.2.1254  0.361
2007 Gleissner CA, Leitinger N, Ley K. Effects of native and modified low-density lipoproteins on monocyte recruitment in atherosclerosis. Hypertension (Dallas, Tex. : 1979). 50: 276-83. PMID 17548720 DOI: 10.1161/Hypertensionaha.107.089854  0.372
2007 Zarbock A, Lowell CA, Ley K. Spleen tyrosine kinase Syk is necessary for E-selectin-induced alpha(L)beta(2) integrin-mediated rolling on intercellular adhesion molecule-1. Immunity. 26: 773-83. PMID 17543554 DOI: 10.1016/J.Immuni.2007.04.011  0.34
2007 Rychak JJ, Klibanov AL, Ley KF, Hossack JA. Enhanced targeting of ultrasound contrast agents using acoustic radiation force. Ultrasound in Medicine & Biology. 33: 1132-9. PMID 17445966 DOI: 10.1016/J.Ultrasmedbio.2007.01.005  0.672
2007 Stockton R, Reutershan J, Scott D, Sanders J, Ley K, Schwartz MA. Induction of vascular permeability: beta PIX and GIT1 scaffold the activation of extracellular signal-regulated kinase by PAK. Molecular Biology of the Cell. 18: 2346-55. PMID 17429073 DOI: 10.1091/Mbc.E06-07-0584  0.312
2007 Reutershan J, Stockton R, Zarbock A, Sullivan GW, Chang D, Scott D, Schwartz MA, Ley K. Blocking p21-activated kinase reduces lipopolysaccharide-induced acute lung injury by preventing polymorphonuclear leukocyte infiltration. American Journal of Respiratory and Critical Care Medicine. 175: 1027-35. PMID 17322107 DOI: 10.1164/Rccm.200612-1822Oc  0.314
2007 Cho HJ, Shashkin P, Gleissner CA, Dunson D, Jain N, Lee JK, Miller Y, Ley K. Induction of dendritic cell-like phenotype in macrophages during foam cell formation. Physiological Genomics. 29: 149-60. PMID 17244792 DOI: 10.1152/Physiolgenomics.00051.2006  0.349
2007 Zarbock A, Singbartl K, Ley K. Complete reversal of acid-induced acute lung injury by blocking of platelet-neutrophil aggregation. The Journal of Clinical Investigation. 116: 3211-9. PMID 17143330 DOI: 10.1172/Jci29499  0.308
2007 Ley K. To transmigrate or not to transmigrate Blood. 109: 5072-5073. DOI: 10.1182/Blood-2007-03-081851  0.311
2006 Klibanov AL, Rychak JJ, Yang WC, Alikhani S, Li B, Acton S, Lindner JR, Ley K, Kaul S. Targeted ultrasound contrast agent for molecular imaging of inflammation in high-shear flow. Contrast Media & Molecular Imaging. 1: 259-66. PMID 17191766 DOI: 10.1002/Cmmi.113  0.69
2006 Sperandio M, Pickard J, Unnikrishnan S, Acton ST, Ley K. Analysis of leukocyte rolling in vivo and in vitro. Methods in Enzymology. 416: 346-71. PMID 17113878 DOI: 10.1016/S0076-6879(06)16023-1  0.353
2006 Sperandio M, Frommhold D, Babushkina I, Ellies LG, Olson TS, Smith ML, Fritzsching B, Pauly E, Smith DF, Nobiling R, Linderkamp O, Marth JD, Ley K. Alpha 2,3-sialyltransferase-IV is essential for L-selectin ligand function in inflammation. European Journal of Immunology. 36: 3207-15. PMID 17111351 DOI: 10.1002/Eji.200636157  0.31
2006 Rivera-Nieves J, Ho J, Bamias G, Ivashkina N, Ley K, Oppermann M, Cominelli F. Antibody blockade of CCL25/CCR9 ameliorates early but not late chronic murine ileitis. Gastroenterology. 131: 1518-29. PMID 17101325 DOI: 10.1053/J.Gastro.2006.08.031  0.324
2006 Rychak JJ, Li B, Acton ST, Leppänen A, Cummings RD, Ley K, Klibanov AL. Selectin ligands promote ultrasound contrast agent adhesion under shear flow. Molecular Pharmaceutics. 3: 516-24. PMID 17009850 DOI: 10.1021/mp0600541  0.677
2006 Smith DF, Deem TL, Bruce AC, Reutershan J, Wu D, Ley K. Leukocyte phosphoinositide-3 kinase {gamma} is required for chemokine-induced, sustained adhesion under flow in vivo. Journal of Leukocyte Biology. 80: 1491-9. PMID 16997858 DOI: 10.1189/Jlb.0306227  0.388
2006 Whetzel AM, Bolick DT, Srinivasan S, Macdonald TL, Morris MA, Ley K, Hedrick CC. Sphingosine-1 phosphate prevents monocyte/endothelial interactions in type 1 diabetic NOD mice through activation of the S1P1 receptor. Circulation Research. 99: 731-9. PMID 16960101 DOI: 10.1161/01.Res.0000244088.33375.52  0.301
2006 Ley K, Smith E, Stark MA. IL-17A-producing neutrophil-regulatory Tn lymphocytes. Immunologic Research. 34: 229-42. PMID 16891673 DOI: 10.1385/Ir:34:3:229  0.729
2006 Rychak JJ, Lindner JR, Ley K, Klibanov AL. Deformable gas-filled microbubbles targeted to P-selectin. Journal of Controlled Release : Official Journal of the Controlled Release Society. 114: 288-99. PMID 16887229 DOI: 10.1016/J.Jconrel.2006.06.008  0.691
2006 Galkina E, Kadl A, Sanders J, Varughese D, Sarembock IJ, Ley K. Lymphocyte recruitment into the aortic wall before and during development of atherosclerosis is partially L-selectin dependent. The Journal of Experimental Medicine. 203: 1273-82. PMID 16682495 DOI: 10.1084/Jem.20052205  0.382
2006 Rivera-Nieves J, Burcin TL, Olson TS, Morris MA, McDuffie M, Cominelli F, Ley K. Critical role of endothelial P-selectin glycoprotein ligand 1 in chronic murine ileitis. The Journal of Experimental Medicine. 203: 907-17. PMID 16567389 DOI: 10.1084/Jem.20052530  0.383
2006 Olson TS, Reuter BK, Scott KG, Morris MA, Wang XM, Hancock LN, Burcin TL, Cohn SM, Ernst PB, Cominelli F, Meddings JB, Ley K, Pizarro TT. The primary defect in experimental ileitis originates from a nonhematopoietic source. The Journal of Experimental Medicine. 203: 541-52. PMID 16505137 DOI: 10.1084/Jem.20050407  0.347
2006 Reutershan J, Morris MA, Burcin TL, Smith DF, Chang D, Saprito MS, Ley K. Critical role of endothelial CXCR2 in LPS-induced neutrophil migration into the lung. The Journal of Clinical Investigation. 116: 695-702. PMID 16485040 DOI: 10.1172/Jci27009  0.351
2006 Basit A, Reutershan J, Morris MA, Solga M, Rose CE, Ley K. ICAM-1 and LFA-1 play critical roles in LPS-induced neutrophil recruitment into the alveolar space. American Journal of Physiology. Lung Cellular and Molecular Physiology. 291: L200-7. PMID 16461431 DOI: 10.1152/Ajplung.00346.2005  0.517
2006 Chesnutt BC, Smith DF, Raffler NA, Smith ML, White EJ, Ley K. Induction of LFA-1-dependent neutrophil rolling on ICAM-1 by engagement of E-selectin. Microcirculation (New York, N.Y. : 1994). 13: 99-109. PMID 16459323 DOI: 10.1080/10739680500466376  0.303
2006 Bachmann C, Klibanov AL, Olson TS, Sonnenschein JR, Rivera-Nieves J, Cominelli F, Ley KF, Lindner JR, Pizarro TT. Targeting mucosal addressin cellular adhesion molecule (MAdCAM)-1 to noninvasively image experimental Crohn's disease. Gastroenterology. 130: 8-16. PMID 16401463 DOI: 10.1053/J.Gastro.2005.11.009  0.777
2006 Galkina E, Ley K. Double jeopardy: how soluble P-selectin activates leukocytes in peripheral arterial occlusive disease. Circulation Research. 98: 12-4. PMID 16397153 DOI: 10.1161/01.Res.0000200409.65882.14  0.377
2006 Klibanov AL, Hossack J, Cho YK, Yang WC, Rychak JJ, Ley KF. Gas‐filled microbubbles—Contrast agents for targeted molecular imaging The Journal of the Acoustical Society of America. 119: 3438-3438. DOI: 10.1121/1.4786919  0.657
2006 Klibanov A, Rychak J, Yang W, Li B, Acton S, Lindner J, Ley K, Kaul S. CMR 2005: 8.03: Targeted ultrasound contrast agents for molecular imaging in high-shear flow Contrast Media & Molecular Imaging. 1: 74-74. DOI: 10.1002/Cmmi.48  0.642
2005 Shashkin P, Dragulev B, Ley K. Macrophage differentiation to foam cells. Current Pharmaceutical Design. 11: 3061-3072. PMID 16178764 DOI: 10.2174/1381612054865064  0.316
2005 Smalley DM, Ley K. L-selectin: mechanisms and physiological significance of ectodomain cleavage. Journal of Cellular and Molecular Medicine. 9: 255-66. PMID 15963248 DOI: 10.1111/J.1582-4934.2005.Tb00354.X  0.305
2005 Reutershan J, Basit A, Galkina EV, Ley K. Sequential recruitment of neutrophils into lung and bronchoalveolar lavage fluid in LPS-induced acute lung injury. American Journal of Physiology. Lung Cellular and Molecular Physiology. 289: L807-15. PMID 15951336 DOI: 10.1152/Ajplung.00477.2004  0.436
2005 Smith DF, Galkina E, Ley K, Huo Y. GRO family chemokines are specialized for monocyte arrest from flow. American Journal of Physiology. Heart and Circulatory Physiology. 289: H1976-84. PMID 15937099 DOI: 10.1152/Ajpheart.00153.2005  0.338
2005 Stark MA, Huo Y, Burcin TL, Morris MA, Olson TS, Ley K. Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17. Immunity. 22: 285-94. PMID 15780986 DOI: 10.1016/J.Immuni.2005.01.011  0.727
2005 Rivera-Nieves J, Olson T, Bamias G, Bruce A, Solga M, Knight RF, Hoang S, Cominelli F, Ley K. L-selectin, alpha 4 beta 1, and alpha 4 beta 7 integrins participate in CD4+ T cell recruitment to chronically inflamed small intestine. Journal of Immunology (Baltimore, Md. : 1950). 174: 2343-52. PMID 15699171 DOI: 10.4049/Jimmunol.174.4.2343  0.313
2005 Ley K, Deem TL. Oxidative modification of leukocyte adhesion. Immunity. 22: 5-7. PMID 15664154 DOI: 10.1016/J.Immuni.2005.01.002  0.341
2005 Klibanov A, Rychak J, Kaul S, Ley K, Lindner J. Fold-Carrying Particles: Improvement of Targeted Microbubble Attachment Academic Radiology. 12: S43-S44. DOI: 10.1016/J.Acra.2005.02.031  0.65
2004 Smith ML, Olson TS, Ley K. CXCR2- and E-selectin-induced neutrophil arrest during inflammation in vivo. The Journal of Experimental Medicine. 200: 935-9. PMID 15466624 DOI: 10.1084/Jem.20040424  0.36
2004 Huo Y, Zhao L, Hyman MC, Shashkin P, Harry BL, Burcin T, Forlow SB, Stark MA, Smith DF, Clarke S, Srinivasan S, Hedrick CC, Praticò D, Witztum JL, Nadler JL, ... ... Ley K, et al. Critical role of macrophage 12/15-lipoxygenase for atherosclerosis in apolipoprotein E-deficient mice. Circulation. 110: 2024-31. PMID 15451785 DOI: 10.1161/01.Cir.0000143628.37680.F6  0.763
2004 Koszalka P, Ozüyaman B, Huo Y, Zernecke A, Flögel U, Braun N, Buchheiser A, Decking UK, Smith ML, Sévigny J, Gear A, Weber AA, Molojavyi A, Ding Z, Weber C, ... Ley K, et al. Targeted disruption of cd73/ecto-5'-nucleotidase alters thromboregulation and augments vascular inflammatory response. Circulation Research. 95: 814-21. PMID 15358667 DOI: 10.1161/01.Res.0000144796.82787.6F  0.352
2004 Dunne JL, Goobic AP, Acton ST, Ley K. A novel method to analyze leukocyte rolling behavior in vivo. Biological Procedures Online. 6: 173-179. PMID 15346173 DOI: 10.1251/Bpo87  0.691
2004 Olson TS, Bamias G, Naganuma M, Rivera-Nieves J, Burcin TL, Ross W, Morris MA, Pizarro TT, Ernst PB, Cominelli F, Ley K. Expanded B cell population blocks regulatory T cells and exacerbates ileitis in a murine model of Crohn disease. The Journal of Clinical Investigation. 114: 389-98. PMID 15286805 DOI: 10.1172/Jci20855  0.325
2004 Gakidis MA, Cullere X, Olson T, Wilsbacher JL, Zhang B, Moores SL, Ley K, Swat W, Mayadas T, Brugge JS. Vav GEFs are required for beta2 integrin-dependent functions of neutrophils. The Journal of Cell Biology. 166: 273-82. PMID 15249579 DOI: 10.1083/Jcb.200404166  0.313
2004 Long DS, Smith ML, Pries AR, Ley K, Damiano ER. Microviscometry reveals reduced blood viscosity and altered shear rate and shear stress profiles in microvessels after hemodilution. Proceedings of the National Academy of Sciences of the United States of America. 101: 10060-5. PMID 15220478 DOI: 10.1073/Pnas.0402937101  0.301
2004 Ley K, Kansas GS. Selectins in T-cell recruitment to non-lymphoid tissues and sites of inflammation. Nature Reviews. Immunology. 4: 325-35. PMID 15122198 DOI: 10.1038/Nri1351  0.323
2004 Takalkar AM, Klibanov AL, Rychak JJ, Lindner JR, Ley K. Binding and detachment dynamics of microbubbles targeted to P-selectin under controlled shear flow. Journal of Controlled Release : Official Journal of the Controlled Release Society. 96: 473-82. PMID 15120903 DOI: 10.1016/J.Jconrel.2004.03.002  0.681
2004 Smith ML, Sperandio M, Galkina EV, Ley K. Autoperfused mouse flow chamber reveals synergistic neutrophil accumulation through P-selectin and E-selectin. Journal of Leukocyte Biology. 76: 985-93. PMID 15075351 DOI: 10.1189/Jlb.1003483  0.321
2004 Manka D, Forlow SB, Sanders JM, Hurwitz D, Bennett DK, Green SA, Ley K, Sarembock IJ. Critical role of platelet P-selectin in the response to arterial injury in apolipoprotein-E-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 1124-9. PMID 15072990 DOI: 10.1161/01.Atv.0000127619.04687.F4  0.725
2004 Fischer JJ, Huo Y, Bennett DK, Bevard M, Davis CJ, Ley K, Sarembock IJ. 1102-53 CX3CR1 gene disruption is not associated with decreased neointima formation after carotid wire injury in apolipoprotein-E deficient mice Journal of the American College of Cardiology. 43: A69. DOI: 10.1016/S0735-1097(04)90289-6  0.303
2003 Dunne JL, Collins RG, Beaudet AL, Ballantyne CM, Ley K. Mac-1, but not LFA-1, uses intercellular adhesion molecule-1 to mediate slow leukocyte rolling in TNF-alpha-induced inflammation. Journal of Immunology (Baltimore, Md. : 1950). 171: 6105-11. PMID 14634125 DOI: 10.4049/Jimmunol.171.11.6105  0.72
2003 Sperandio M, Smith ML, Forlow SB, Olson TS, Xia L, McEver RP, Ley K. P-selectin glycoprotein ligand-1 mediates L-selectin-dependent leukocyte rolling in venules. The Journal of Experimental Medicine. 197: 1355-63. PMID 12756271 DOI: 10.1084/Jem.20021854  0.341
2003 Phillips JW, Barringhaus KG, Sanders JM, Hesselbacher SE, Czarnik AC, Manka D, Vestweber D, Ley K, Sarembock IJ. Single injection of P-selectin or P-selectin glycoprotein ligand-1 monoclonal antibody blocks neointima formation after arterial injury in apolipoprotein E-deficient mice. Circulation. 107: 2244-9. PMID 12707243 DOI: 10.1161/01.Cir.0000065604.56839.18  0.736
2003 Thatte J, Dabak V, Williams MB, Braciale TJ, Ley K. LFA-1 is required for retention of effector CD8 T cells in mouse lungs. Blood. 101: 4916-22. PMID 12623847 DOI: 10.1182/Blood-2002-10-3159  0.341
2003 Shashkin P, Simpson D, Mishin V, Chesnutt B, Ley K. Expression of CXCL16 in human T cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 148-9. PMID 12524239 DOI: 10.1161/01.Atv.0000043906.61088.4B  0.339
2003 Bachmann C, Klibanov AL, Cominelli F, Ley KF, Lindner JR, Pizarro TT. Targeting MAdCAM-1: A novel non-invasive diagnostic tool for therapeutic monitoring and the evaluation of active intestinal inflammation Gastroenterology. 124: A192. DOI: 10.1016/S0016-5085(03)80963-0  0.761
2002 Ellies LG, Sperandio M, Underhill GH, Yousif J, Smith M, Priatel JJ, Kansas GS, Ley K, Marth JD. Sialyltransferase specificity in selectin ligand formation. Blood. 100: 3618-25. PMID 12393657 DOI: 10.1182/Blood-2002-04-1007  0.34
2002 Forlow SB, White EJ, Thomas KL, Bagby GJ, Foley PL, Ley K. T cell requirement for development of chronic ulcerative dermatitis in E- and P-selectin-deficient mice. Journal of Immunology (Baltimore, Md. : 1950). 169: 4797-804. PMID 12391189 DOI: 10.4049/Jimmunol.169.9.4797  0.344
2002 Prorock AJ, Hafezi-Moghadam A, Laubach VE, Liao JK, Ley K. Vascular protection by estrogen in ischemia-reperfusion injury requires endothelial nitric oxide synthase. American Journal of Physiology. Heart and Circulatory Physiology. 284: H133-40. PMID 12388253 DOI: 10.1152/Ajpheart.00957.2001  0.345
2002 Forlow SB, Foley PL, Ley K. Severely reduced neutrophil adhesion and impaired host defense against fecal and commensal bacteria in CD18-/-P-selectin-/- double null mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 1488-96. PMID 12374771 DOI: 10.1096/Fj.02-0230Com  0.334
2002 Schober A, Manka D, Von Hundelshausen P, Huo Y, Hanrath P, Sarembock IJ, Ley K, Weber C. Deposition of platelet RANTES triggering monocyte recruitment requires P-selectin and is involved in neointima formation after arterial injury Circulation. 106: 1523-1529. PMID 12234959 DOI: 10.1161/01.Cir.0000028590.02477.6F  0.749
2002 Xia L, Sperandio M, Yago T, McDaniel JM, Cummings RD, Pearson-White S, Ley K, McEver RP. P-selectin glycoprotein ligand-1-deficient mice have impaired leukocyte tethering to E-selectin under flow. The Journal of Clinical Investigation. 109: 939-50. PMID 11927621 DOI: 10.1172/Jci14151  0.359
2002 Dunne JL, Ballantyne CM, Beaudet AL, Ley K. Control of leukocyte rolling velocity in TNF-alpha-induced inflammation by LFA-1 and Mac-1. Blood. 99: 336-41. PMID 11756189 DOI: 10.1182/Blood.V99.1.336  0.699
2002 Ley K. Pathways and bottlenecks in the web of inflammatory adhesion molecules and chemoattractants. Immunologic Research. 24: 87-95. PMID 11485212 DOI: 10.1385/Ir:24:1:87  0.359
2001 Bradley Forlow S, Schurr JR, Kolls JK, Bagby GJ, Schwarzenberger PO, Ley K. Increased granulopoiesis through interleukin-17 and granulocyte colony-stimulating factor in leukocyte adhesion molecule-deficient mice Blood. 98: 3309-3314. PMID 11719368 DOI: 10.1182/Blood.V98.12.3309  0.361
2001 Huo Y, Weber C, Forlow SB, Sperandio M, Thatte J, Mack M, Jung S, Littman DR, Ley K. The chemokine KC, but not monocyte chemoattractant protein-1, triggers monocyte arrest on early atherosclerotic endothelium Journal of Clinical Investigation. 108: 1307-1314. PMID 11696575 DOI: 10.1172/Jci12877  0.4
2001 Singbartl K, Forlow SB, Ley K. Platelet, but not endothelial, P-selectin is critical for neutrophil-mediated acute postischemic renal failure The Faseb Journal. 15: 2337-2344. PMID 11689459 DOI: 10.1096/Fj.01-0199Com  0.315
2001 Huo Y, Ley K. Adhesion molecules and atherogenesis Acta Physiologica Scandinavica. 173: 35-43. PMID 11678724 DOI: 10.1046/J.1365-201X.2001.00882.X  0.416
2001 Ley K. Plugging the leaks. Nature Medicine. 7: 1105-6. PMID 11590428 DOI: 10.1038/Nm1001-1105  0.308
2001 Lysiak JJ, Turner SD, Nguyen QAT, Singbartl K, Ley K, Turner TT. Essential role of neutrophils in germ cell-specific apoptosis following ischemia/reperfusion injury of the mouse testis Biology of Reproduction. 65: 718-725. PMID 11514333 DOI: 10.1095/Biolreprod65.3.718  0.363
2001 Sperandio M, Forlow SB, Thatte J, Ellies LG, Marth JD, Ley K. Differential requirements for core2 glucosaminyltransferase for endothelial L-selectin ligand function in vivo Journal of Immunology. 167: 2268-2274. PMID 11490014 DOI: 10.4049/Jimmunol.167.4.2268  0.316
2001 Collins RG, Jung U, Ramirez M, Bullard DC, Hicks MJ, Smith CW, Ley K, Beaudet AL. Dermal and pulmonary inflammatory disease in E-selectin and P-selectin double-null mice is reduced in triple-selectin-null mice. Blood. 98: 727-35. PMID 11468173 DOI: 10.1182/Blood.V98.3.727  0.358
2001 Singbartl K, Thatte J, Smith ML, Wethmar K, Day K, Ley K. A CD2-green fluorescence protein-transgenic mouse reveals very late antigen-4-dependent CD8+ lymphocyte rolling in inflamed venules. Journal of Immunology (Baltimore, Md. : 1950). 166: 7520-6. PMID 11390506 DOI: 10.4049/Jimmunol.166.12.7520  0.312
2001 Sperandio M, Thatte A, Foy D, Ellies LG, Marth JD, Ley K. Severe impairment of leukocyte rolling in venules of core 2 glucosaminyltransferase-deficient mice Blood. 97: 3812-3819. PMID 11389021 DOI: 10.1182/Blood.V97.12.3812  0.348
2001 Ley K, Huo Y. VCAM-1 is critical in atherosclerosis Journal of Clinical Investigation. 107: 1209-1210. PMID 11375406 DOI: 10.1172/Jci13005  0.411
2001 Ley K. Functions of selectins. Results and Problems in Cell Differentiation. 33: 177-200. PMID 11190674 DOI: 10.1007/978-3-540-46410-5_10  0.367
2001 Manka D, Collins RG, Ley K, Beaudet AL, Sarembock IJ. Absence of p-selectin, but not intercellular adhesion molecule-1, attenuates neointimal growth after arterial injury in apolipoprotein e-deficient mice. Circulation. 103: 1000-5. PMID 11181476 DOI: 10.1161/01.Cir.103.7.1000  0.732
2001 Forlow SB, Ley K. Selectin-independent leukocyte rolling and adhesion in mice deficient in E-, P-, and L-selectin and ICAM-1 American Journal of Physiology-Heart and Circulatory Physiology. 280. PMID 11158961 DOI: 10.1152/Ajpheart.2001.280.2.H634  0.345
2000 Forlow SB, White EJ, Barlow SC, Feldman SH, Lu H, Bagby GJ, Beaudet AL, Bullard DC, Ley K. Severe inflammatory defect and reduced viability in CD18 and E-selectin double-mutant mice. The Journal of Clinical Investigation. 106: 1457-66. PMID 11120753 DOI: 10.1172/Jci10555  0.331
2000 Lindner JR, Kahn ML, Coughlin SR, Sambrano GR, Schauble E, Bernstein D, Foy D, Hafezi-Moghadam A, Ley K. Delayed onset of inflammation in protease-activated receptor-2-deficient mice. Journal of Immunology (Baltimore, Md. : 1950). 165: 6504-10. PMID 11086091 DOI: 10.4049/Jimmunol.165.11.6504  0.386
2000 Foy DS, Ley K. Intercellular adhesion molecule-1 is required for chemoattractant-induced leukocyte adhesion in resting, but not inflamed, venules in vivo. Microvascular Research. 60: 249-260. PMID 11078641 DOI: 10.1006/Mvre.2000.2272  0.35
2000 Manka DR, Gilson W, Sarembock I, Ley K, Berr SS. Noninvasive in vivo magnetic resonance imaging of injury-induced neointima formation in the carotid artery of the apolipoprotein-E null mouse. Journal of Magnetic Resonance Imaging : Jmri. 12: 790-4. PMID 11050652 DOI: 10.1002/1522-2586(200011)12:5<790::Aid-Jmri19>3.0.Co;2-6  0.715
2000 Singbartl K, Ley K. Protection from ischemia-reperfusion induced severe acute renal failure by blocking E-selectin. Critical Care Medicine. 28: 2507-2514. PMID 10921586 DOI: 10.1097/00003246-200007000-00053  0.331
2000 Lindner JR, Dayton PA, Coggins MP, Ley K, Song J, Ferrara K, Kaul S. Noninvasive imaging of inflammation by ultrasound detection of Phagocytosed microbubbles Circulation. 102: 531-538. PMID 10920065 DOI: 10.1161/01.Cir.102.5.531  0.342
2000 Huo Y, Hafezi-Moghadam A, Ley K. Role of vascular cell adhesion molecule-1 and fibronectin connecting segment-1 in monocyte rolling and adhesion on early atherosclerotic lesions. Circulation Research. 87: 153-9. PMID 10904000 DOI: 10.1161/01.Res.87.2.153  0.37
2000 Kunkel EJ, Dunne JL, Ley K. Leukocyte arrest during cytokine-dependent inflammation in vivo. Journal of Immunology (Baltimore, Md. : 1950). 164: 3301-8. PMID 10706723 DOI: 10.4049/Jimmunol.164.6.3301  0.709
2000 Lindner JR, Coggins MP, Kaul S, Klibanov AL, Brandenburger GH, Ley K. Microbubble persistence in the microcirculation during ischemia/reperfusion and inflammation is caused by integrin- and complement- mediated adherence to activated leukocytes Circulation. 101: 668-675. PMID 10673260 DOI: 10.1161/01.Cir.101.6.668  0.324
1999 Manka DR, Wiegman P, Din S, Sanders JM, Green SA, Gimple LW, Ragosta M, Powers ER, Ley K, Sarembock IJ. Arterial injury increases expression of inflammatory adhesion molecules in the carotid arteries of apolipoprotein-E-deficient mice. Journal of Vascular Research. 36: 372-8. PMID 10559677 DOI: 10.1159/000025676  0.748
1999 Kamochi M, Kamochi F, Kim YB, Sawh S, Sanders JM, Sarembock I, Green S, Young JS, Ley K, Fu SM, Rose CE. P-selectin and ICAM-1 mediate endotoxin-induced neutrophil recruitment and injury to the lung and liver. The American Journal of Physiology. 277: L310-9. PMID 10444525 DOI: 10.1152/Ajplung.1999.277.2.L310  0.348
1999 Ramos CL, Huo Y, Jung U, Ghosh S, Manka DR, Sarembock IJ, Ley K. Direct demonstration of P-selectin- and VCAM-1-dependent mononuclear cell rolling in early atherosclerotic lesions of apolipoprotein E-deficient mice. Circulation Research. 84: 1237-44. PMID 10364560 DOI: 10.1161/01.Res.84.11.1237  0.758
1999 Hafezi-Moghadam A, Ley K. Relevance of L-selectin shedding for leukocyte rolling in vivo. The Journal of Experimental Medicine. 189: 939-48. PMID 10075977 DOI: 10.1084/Jem.189.6.939  0.331
1999 Bishop GG, Wiegman P, McNamara C, Din S, Sanders J, Hesselbacher S, Feldman M, McPherson JA, Humphries JE, Hammarskjold M, Gimple LW, Ragosta M, Powers ER, Dickek D, Owens GK, ... ... Ley K, et al. Selected Comments on and Replies to the Article Journal of Vascular Research. 36: 352-352. DOI: 10.1159/000025673  0.68
1999 Bishop GG, Wiegman P, McNamara C, Din S, Sanders J, Hesselbacher S, Feldman M, McPherson JA, Humphries JE, Hammarskjold M, Gimple LW, Ragosta M, Powers ER, Dickek D, Owens GK, ... ... Ley K, et al. Editorial: The JVR Internet Discussion Forum Journal of Vascular Research. 36: 343-343. DOI: 10.1159/000025671  0.672
1998 Jung U, Norman KE, Scharffetter-Kochanek K, Beaudet AL, Ley K. Transit time of leukocytes rolling through venules controls cytokine-induced inflammatory cell recruitment in vivo. The Journal of Clinical Investigation. 102: 1526-33. PMID 9788965 DOI: 10.1172/Jci119893  0.371
1998 Aigner S, Ramos CL, Hafezi-Moghadam A, Lawrence MB, Friederichs J, Altevogt P, Ley K. CD24 mediates rolling of breast carcinoma cells on P-selectin. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 12: 1241-51. PMID 9737727 DOI: 10.1096/Fasebj.12.12.1241  0.31
1998 Ley K, Allietta M, Bullard DC, Morgan S. Importance of E-selectin for firm leukocyte adhesion in vivo. Circulation Research. 83: 287-94. PMID 9710121 DOI: 10.1161/01.Res.83.3.287  0.373
1998 Scharffetter-Kochanek K, Lu H, Norman K, van Nood N, Munoz F, Grabbe S, McArthur M, Lorenzo I, Kaplan S, Ley K, Smith CW, Montgomery CA, Rich S, Beaudet AL. Spontaneous skin ulceration and defective T cell function in CD18 null mice. The Journal of Experimental Medicine. 188: 119-31. PMID 9653089 DOI: 10.1084/Jem.188.1.119  0.318
1998 Steeber DA, Campbell MA, Basit A, Ley K, Tedder TF. Optimal selectin-mediated rolling of leukocytes during inflammation in vivo requires intercellular adhesion molecule-1 expression. Proceedings of the National Academy of Sciences of the United States of America. 95: 7562-7. PMID 9636189 DOI: 10.1073/Pnas.95.13.7562  0.532
1998 Jung U, Ramos CL, Bullard DC, Ley K. Gene-targeted mice reveal importance of L-selectin-dependent rolling for neutrophil adhesion. The American Journal of Physiology. 274: H1785-91. PMID 9612391 DOI: 10.1152/Ajpheart.1998.274.5.H1785  0.363
1998 Kunkel EJ, Chomas JE, Ley K. Role of primary and secondary capture for leukocyte accumulation in vivo Circulation Research. 82: 30-38. PMID 9440702 DOI: 10.1161/01.Res.82.1.30  0.315
1998 Norman KE, Anderson GP, Kolb HC, Ley K, Ernst B. Sialyl Lewisx (sLex) and an sLexMimetic, CGP69669A, Disrupt E-Selectin–Dependent Leukocyte Rolling In Vivo Blood. 91: 475-483. DOI: 10.1182/Blood.V91.2.475.475_475_483  0.338
1997 Morgan SJ, Moore MW, Cacalano G, Ley K. Brief communication: Reduced leukocyte adhesion response and absence of slow leukocyte rolling in interleukin-8 receptor-deficient mice Microvascular Research. 54: 188-191. PMID 9327391 DOI: 10.1006/Mvre.1997.2029  0.319
1997 Kunkel EJ, Jung U, Ley K. TNF-alpha induces selectin-mediated leukocyte rolling in mouse cremaster muscle arterioles. The American Journal of Physiology. 272: H1391-400. PMID 9087616 DOI: 10.1152/Ajpheart.1997.272.3.H1391  0.347
1997 Lawrence MB, Kansas GS, Kunkel EJ, Ley K. Threshold levels of fluid shear promote leukocyte adhesion through selectins (CD62L,P,E) The Journal of Cell Biology. 136: 717-27. PMID 9024700 DOI: 10.1083/Jcb.136.3.717  0.331
1997 Damiano ER, Westheider J, Tözeren A, Ley K. Variation in the velocity, deformation, and adhesion energy density of leukocytes rolling within venules. Circulation Research. 79: 1122-30. PMID 8943950 DOI: 10.1161/01.Res.79.6.1122  0.314
1997 Borges E, Eytner R, Moll T, Steegmaier M, Campbell MA, Ley K, Mossmann H, Vestweber D. The P-Selectin Glycoprotein Ligand-1 Is Important for Recruitment of Neutrophils Into Inflamed Mouse Peritoneum Blood. 90: 1934-1942. DOI: 10.1182/Blood.V90.5.1934  0.318
1997 Zakrzewicz A, Gräfe M, Terbeek D, Bongrazio M, Auch-Schwelk W, Walzog B, Graf K, Fleck E, Ley K, Gaehtgens P. L-Selectin–Dependent Leukocyte Adhesion to Microvascular But Not to Macrovascular Endothelial Cells of the Human Coronary System Blood. 89: 3228-3235. DOI: 10.1182/Blood.V89.9.3228  0.328
1997 Ramos CL, Kunkel EJ, Lawrence MB, Jung U, Vestweber D, Bosse R, McIntyre KW, Gillooly KM, Norton CR, Wolitzky BA, Ley K. Differential Effect of E-Selectin Antibodies on Neutrophil Rolling and Recruitment to Inflammatory Sites Blood. 89: 3009-3018. DOI: 10.1182/Blood.V89.8.3009  0.331
1996 Jung U, Bullard DC, Tedder TF, Ley K. Velocity differences between L- and P-selectin-dependent neutrophil rolling in venules of mouse cremaster muscle in vivo. The American Journal of Physiology. 271: H2740-7. PMID 8997339 DOI: 10.1152/Ajpheart.1996.271.6.H2740  0.332
1996 Kunkel EJ, Ley K. Distinct phenotype of E-selectin-deficient mice: E-selectin is required for slow leukocyte rolling in vivo Circulation Research. 79: 1196-1204. PMID 8943958 DOI: 10.1161/01.Res.79.6.1196  0.364
1996 Kunkel EJ, Jung U, Bullard DC, Norman KE, Wolitzky BA, Vestweber D, Beaudet AL, Ley K. Absence of trauma-induced leukocyte rolling in mice deficient in both P-selectin and intercellular adhesion molecule 1. The Journal of Experimental Medicine. 183: 57-65. PMID 8551244 DOI: 10.1084/Jem.183.1.57  0.381
1996 Ley K. Molecular mechanisms of leukocyte recruitment in the inflammatory process Cardiovascular Research. 32: 733-742. DOI: 10.1016/S0008-6363(96)00066-1  0.364
1995 Norman K, Moore K, McEver R, Ley K. Leukocyte rolling in vivo is mediated by P-selectin glycoprotein ligand- 1 Blood. 86: 4417-4421. DOI: 10.1182/Blood.V86.12.4417.Bloodjournal86124417  0.357
1995 Ley K, Zakrzewicz A, Hanski C, Stoolman L, Kansas G. Sialylated O-glycans and L-selectin sequentially mediate myeloid cell rolling in vivo Blood. 85: 3727-3735. DOI: 10.1182/Blood.V85.12.3727.Bloodjournal85123727  0.307
1994 Ley K. Histamine can induce leukocyte rolling in rat mesenteric venules. American Journal of Physiology-Heart and Circulatory Physiology. 267. PMID 7522403 DOI: 10.1152/Ajpheart.1994.267.3.H1017  0.311
1993 Ley K, Tedder TF, Kansas GS. L-selectin can mediate leukocyte rolling in untreated mesenteric venules in vivo independent of E- or P-selectin Blood. 82: 1632-1638. DOI: 10.1182/Blood.V82.5.1632.1632  0.312
1992 Ley K. Leukocyte adhesion to vascular endothelium. Journal of Reconstructive Microsurgery. 8: 495-503. PMID 1453376 DOI: 10.1055/S-2007-1006736  0.327
1992 Ley K, Gaehtgens P, Spanel-Borowski K. Differential adhesion of granulocytes to five distinct phenotypes of cultured microvascular endothelial cells. Microvascular Research. 43: 119-133. PMID 1374829 DOI: 10.1016/0026-2862(92)90011-D  0.356
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