David M. Karnak, Ph.D. - Publications

Affiliations: 
2004 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Biochemistry

25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Wang W, McMillan MT, Zhao X, Wang Z, Jiang L, Karnak D, Lima F, Parsels JD, Parsels LA, Lawrence TS, Frankel TL, Morgan MA, Green MD, Zhang Q. DNA-PK inhibition and radiation promote anti-tumoral immunity through RNA Polymerase III in pancreatic cancer. Molecular Cancer Research : McR. PMID 35348737 DOI: 10.1158/1541-7786.MCR-21-0725  0.345
2021 Parsels LA, Zhang Q, Karnak D, Parsels JD, Lam K, Willers H, Green MD, Rehemtulla A, Lawrence TS, Morgan MA. Translation of DNA damage response inhibitors as chemoradiation sensitizers from the laboratory to the clinic. International Journal of Radiation Oncology, Biology, Physics. PMID 34348175 DOI: 10.1016/j.ijrobp.2021.07.1708  0.328
2019 Cuneo KC, Devasia T, Sun Y, Schipper MJ, Karnak D, Davis MA, Owen D, Feng M, El Naqa I, Bazzi L, Ten Haken R, Lawrence TS. Serum Levels of Hepatocyte Growth Factor and CD40 Ligand Predict Radiation-Induced Liver Injury. Translational Oncology. 12: 889-894. PMID 31078059 DOI: 10.1016/J.Tranon.2019.04.003  0.303
2019 Chefetz I, Grimley E, Yang K, Hong L, Vinogradova EV, Suciu R, Kovalenko I, Karnak D, Morgan CA, Chtcherbinine M, Buchman C, Huddle B, Barraza S, Morgan M, Bernstein KA, et al. A Pan-ALDH1A Inhibitor Induces Necroptosis in Ovarian Cancer Stem-like Cells. Cell Reports. 26: 3061-3075.e6. PMID 30865894 DOI: 10.1016/J.Celrep.2019.02.032  0.376
2019 Jackson WC, Hartman HE, Gharzai LA, Maurino C, Karnak D, Mendiratta-Lala M, Parikh ND, Mayo C, Haken RKT, Schipper M, Cuneo KC, Lawrence TS, Owen D. A Mid-Treatment Increase in Albi Score Is Strongly Associated with Treatment Related Toxicity Following Liver Radiation Therapy International Journal of Radiation Oncology Biology Physics. 105. DOI: 10.1016/J.Ijrobp.2019.06.277  0.303
2019 Cuneo KC, Devasia TP, Karnak D, Ray D, Owen D, Maurino C, Schipper M, Lawrence TS. Tumor Necrosis Factor Receptor 1 Levels Predict Radiation Induced Liver Injury International Journal of Radiation Oncology Biology Physics. 105. DOI: 10.1016/J.Ijrobp.2019.06.168  0.304
2017 Parsels LA, Karnak D, Parsels J, Zhang Q, Vélez-Padilla J, Reichert Z, Wahl DR, Maybaum J, O'Connor MJ, Lawrence TS, Morgan MA. PARP1 Trapping and DNA Replication Stress Enhance Radiosensitization with Combined WEE1 and PARP Inhibitors. Molecular Cancer Research : McR. PMID 29133592 DOI: 10.1158/1541-7786.Mcr-17-0455  0.406
2016 Cuneo KC, Morgan MA, Davis MA, Parcels LA, Parcels J, Karnak D, Ryan C, Liu N, Maybaum J, Lawrence TS. Wee1 Kinase Inhibitor AZD1775 Radiosensitizes Hepatocellular Carcinoma Regardless of TP53 Mutational Status Through Induction of Replication Stress. International Journal of Radiation Oncology, Biology, Physics. PMID 26975930 DOI: 10.1016/J.Ijrobp.2016.01.028  0.4
2016 Zhang Q, Karnak D, Tan M, Lawrence TS, Morgan MA, Sun Y. FBXW7 Facilitates Nonhomologous End-Joining via K63-Linked Polyubiquitylation of XRCC4. Molecular Cell. PMID 26774286 DOI: 10.1016/J.Molcel.2015.12.010  0.388
2016 Parsels LA, Karnak D, Parsels JD, Reichert Z, Maybaum J, Lawrence TS, Morgan MA. Abstract 519: Combined inhibition of WEE1 and PARP1 radiosensitizes KRAS mutant non-small cell lung cancers via inhibition of DSB repair Cancer Research. 76: 519-519. DOI: 10.1158/1538-7445.Am2016-519  0.472
2015 Kausar T, Schreiber JS, Karnak D, Parsels LA, Parsels JD, Davis MA, Zhao L, Maybaum J, Lawrence TS, Morgan MA. Sensitization of Pancreatic Cancers to Gemcitabine Chemoradiation by WEE1 Kinase Inhibition Depends on Homologous Recombination Repair. Neoplasia (New York, N.Y.). 17: 757-66. PMID 26585231 DOI: 10.1016/J.Neo.2015.09.006  0.497
2014 Karnak D, Engelke CG, Parsels LA, Kausar T, Wei D, Robertson JR, Marsh KB, Davis MA, Zhao L, Maybaum J, Lawrence TS, Morgan MA. Combined inhibition of Wee1 and PARP1/2 for radiosensitization in pancreatic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 5085-96. PMID 25117293 DOI: 10.1158/1078-0432.Ccr-14-1038  0.52
2014 Kausar T, Parsels LA, Parsels JD, Karnak D, Davis MA, Maybaum J, Lawrence TS, Morgan MA. Abstract 862: Sensitization of pancreatic cancer to chemoradiation by the Wee1 inhibitor AZD1775 Cancer Research. 74: 862-862. DOI: 10.1158/1538-7445.Am2014-862  0.486
2013 Li L, Tang W, Wu X, Karnak D, Meng X, Thompson R, Hao X, Li Y, Qiao XT, Lin J, Fuchs J, Simeone DM, Chen ZN, Lawrence TS, Xu L. HAb18G/CD147 promotes pSTAT3-mediated pancreatic cancer development via CD44s. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 6703-15. PMID 24132924 DOI: 10.1158/1078-0432.Ccr-13-0621  0.307
2013 Engelke CG, Parsels LA, Qian Y, Zhang Q, Karnak D, Robertson JR, Tanska DM, Wei D, Davis MA, Parsels JD, Zhao L, Greenson JK, Lawrence TS, Maybaum J, Morgan MA. Sensitization of pancreatic cancer to chemoradiation by the Chk1 inhibitor MK8776. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 4412-21. PMID 23804422 DOI: 10.1158/1078-0432.Ccr-12-3748  0.503
2013 Wei D, Parsels LA, Karnak D, Davis MA, Parsels JD, Marsh AC, Zhao L, Maybaum J, Lawrence TS, Sun Y, Morgan MA. Inhibition of protein phosphatase 2A radiosensitizes pancreatic cancers by modulating CDC25C/CDK1 and homologous recombination repair. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 4422-32. PMID 23780887 DOI: 10.1158/1078-0432.Ccr-13-0788  0.461
2012 Williams TM, Flecha AR, Keller P, Ram A, Karnak D, Galbán S, Galbán CJ, Ross BD, Lawrence TS, Rehemtulla A, Sebolt-Leopold J. Cotargeting MAPK and PI3K signaling with concurrent radiotherapy as a strategy for the treatment of pancreatic cancer. Molecular Cancer Therapeutics. 11: 1193-202. PMID 22411900 DOI: 10.1158/1535-7163.Mct-12-0098  0.478
2012 Williams TM, Flecha A, Keller P, Ram A, Karnak D, Ross B, Lawrence T, Rehemtulla A, Sebolt-Leopold J. Abstract B43: Co-targeting MAPK and PI3K signaling with concurrent radiotherapy as a strategy for the treatment of pancreatic cancer. Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-B43  0.495
2012 Karnak D, Parsels LA, Maybaum J, Lawrence TS, Morgan MA. Abstract 1459: Combined inhibition of Wee1 and PARP1 sensitizes pancreatic cancer cells to radiation Cancer Research. 72: 1459-1459. DOI: 10.1158/1538-7445.Am2012-1459  0.493
2010 Lian J, Karnak D, Xu L. The Bcl-2-Beclin 1 interaction in (-)-gossypol-induced autophagy versus apoptosis in prostate cancer cells. Autophagy. 6: 1201-3. PMID 20930561 DOI: 10.1038/Cdd.2010.74  0.389
2010 Karnak D, Xu L. Chemosensitization of Prostate Cancer by Modulating Bcl-2 Family Proteins Current Drug Targets. 11: 699-707. PMID 20298153 DOI: 10.2174/138945010791170888  0.433
2010 Lian J, Karnak D, Xu L. The Bcl-2-Beclin 1 interaction in (-)-gossypol-induced autophagy versus apoptosis in prostate cancer cells Autophagy. 6: 1201-1203. DOI: 10.4161/Auto.6.8.13549  0.389
2010 Lian J, Wu X, Tang W, Karnak D, He F, Meng Y, Lawrence TS, Xu L. Abstract 4851: BH-3 mimetics radiosensitizes human prostate cancer via modulating autophagy Cancer Research. 70: 4851-4851. DOI: 10.1158/1538-7445.Am10-4851  0.464
2010 Karnak D, Dai Y, DeSano JT, Tang W, Ljungman M, Lawrence TS, Xu L. Abstract 1394: Pro-apoptotic and anti-tumorigenic effects of a naturally occurring proteasome inhibitor on hormone-refractory prostate cancer Cancer Research. 70: 1394-1394. DOI: 10.1158/1538-7445.Am10-1394  0.505
2007 Domino SE, Karnak DM, Hurd EA. Cell surface fucosylation does not affect development of colon tumors in mice with germline Smad3 mutation. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. 28: 77-83. PMID 17264540 DOI: 10.1159/000099153  0.314
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