Denise E. Kirschner - Publications

Affiliations: 
University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Immunology, Microbiology Biology, Mathematics

83 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Wessler T, Joslyn LR, Borish HJ, Gideon HP, Flynn JL, Kirschner DE, Linderman JJ. A computational model tracks whole-lung Mycobacterium tuberculosis infection and predicts factors that inhibit dissemination. Plos Computational Biology. 16: e1007280. PMID 32433646 DOI: 10.1371/journal.pcbi.1007280  0.52
2019 Wong EA, Evans S, Kraus CR, Engelman KD, Maiello P, Flores WJ, Cadena AM, Klein E, Thomas K, White AG, Causgrove C, Stein B, Tomko J, Mattila JT, Gideon H, ... ... Kirschner DE, et al. IL-10 Impairs Local Immune Response in Lung Granulomas and Lymph Nodes during Early Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 31862711 DOI: 10.4049/jimmunol.1901211  0.52
2018 Marino S, Hult C, Wolberg P, Linderman JJ, Kirschner DE. The Role of Dimensionality in Understanding Granuloma Formation. Computation (Basel, Switzerland). 6. PMID 31258937 DOI: 10.3390/computation6040058  0.36
2018 Joslyn LR, Pienaar E, DiFazio RM, Suliman S, Kagina BM, Flynn JL, Scriba TJ, Linderman JJ, Kirschner DE. Integrating Non-human Primate, Human, and Mathematical Studies to Determine the Influence of BCG Timing on H56 Vaccine Outcomes. Frontiers in Microbiology. 9: 1734. PMID 30177914 DOI: 10.3389/fmicb.2018.01734  0.52
2018 Cicchese JM, Evans S, Hult C, Joslyn LR, Wessler T, Millar JA, Marino S, Cilfone NA, Mattila JT, Linderman JJ, Kirschner DE. Dynamic balance of pro- and anti-inflammatory signals controls disease and limits pathology. Immunological Reviews. 285: 147-167. PMID 30129209 DOI: 10.1111/imr.12671  0.36
2018 Wong EA, Joslyn L, Grant NL, Klein E, Lin PL, Kirschner DE, Flynn JL. Low levels of T cell exhaustion in tuberculous lung granulomas. Infection and Immunity. PMID 29891540 DOI: 10.1128/IAI.00426-18  0.52
2017 Kirschner D, Pienaar E, Marino S, Linderman JJ. A review of computational and mathematical modeling contributions to our understanding of Mycobacterium tuberculosis within-host infection and treatment. Current Opinion in Systems Biology. 3: 170-185. PMID 30714019 DOI: 10.1016/j.coisb.2017.05.014  0.36
2017 Warsinske HC, DiFazio RM, Linderman JJ, Flynn JL, Kirschner DE. Identifying mechanisms driving formation of granuloma-associated fibrosis during Mycobacterium tuberculosis infection. Journal of Theoretical Biology. PMID 28642013 DOI: 10.1016/j.jtbi.2017.06.017  0.52
2016 Marino S, Kirschner DE. A Multi-Compartment Hybrid Computational Model Predicts Key Roles for Dendritic Cells in Tuberculosis Infection. Computation (Basel, Switzerland). 4. PMID 28989808 DOI: 10.3390/computation4040039  0.36
2016 Warsinske HC, Wheaton AK, Kim KK, Linderman JJ, Moore BB, Kirschner DE. Computational Modeling Predicts Simultaneous Targeting of Fibroblasts and Epithelial Cells Is Necessary for Treatment of Pulmonary Fibrosis. Frontiers in Pharmacology. 7: 183. PMID 27445819 DOI: 10.3389/fphar.2016.00183  1
2016 Marino S, Gideon HP, Gong C, Mankad S, McCrone JT, Lin PL, Linderman JJ, Flynn JL, Kirschner DE. Computational and Empirical Studies Predict Mycobacterium tuberculosis-Specific T Cells as a Biomarker for Infection Outcome. Plos Computational Biology. 12: e1004804. PMID 27065304 DOI: 10.1371/journal.pcbi.1004804  1
2016 Pienaar E, Matern WM, Linderman JJ, Bader JS, Kirschner DE. Multi-scale model of Mycobacterium tuberculosis infection maps metabolite and gene perturbations to granuloma sterilization predictions. Infection and Immunity. PMID 26975995 DOI: 10.1128/IAI.01438-15  1
2015 Pienaar E, Dartois V, Linderman JJ, Kirschner DE. In silico evaluation and exploration of antibiotic tuberculosis treatment regimens. Bmc Systems Biology. 9: 79. PMID 26578235 DOI: 10.1186/s12918-015-0221-8  1
2015 Warsinske HC, Ashley SL, Linderman JJ, Moore BB, Kirschner DE. Identifying Mechanisms of Homeostatic Signaling in Fibroblast Differentiation. Bulletin of Mathematical Biology. PMID 26384829 DOI: 10.1007/s11538-015-0096-2  1
2015 Gong C, Linderman JJ, Kirschner D. A population model capturing dynamics of tuberculosis granulomas predicts host infection outcomes. Mathematical Biosciences and Engineering : Mbe. 12: 625-42. PMID 25811559 DOI: 10.3934/mbe.2015.12.625  1
2015 Gideon HP, Phuah J, Myers AJ, Bryson BD, Rodgers MA, Coleman MT, Maiello P, Rutledge T, Marino S, Fortune SM, Kirschner DE, Lin PL, Flynn JL. Variability in tuberculosis granuloma T cell responses exists, but a balance of pro- and anti-inflammatory cytokines is associated with sterilization. Plos Pathogens. 11: e1004603. PMID 25611466 DOI: 10.1371/journal.ppat.1004603  1
2015 Cilfone NA, Ford CB, Marino S, Mattila JT, Gideon HP, Flynn JL, Kirschner DE, Linderman JJ. Computational modeling predicts IL-10 control of lesion sterilization by balancing early host immunity-mediated antimicrobial responses with caseation during mycobacterium tuberculosis infection. Journal of Immunology (Baltimore, Md. : 1950). 194: 664-77. PMID 25512604 DOI: 10.4049/jimmunol.1400734  1
2015 Pienaar E, Cilfone NA, Lin PL, Dartois V, Mattila JT, Butler JR, Flynn JL, Kirschner DE, Linderman JJ. A computational tool integrating host immunity with antibiotic dynamics to study tuberculosis treatment. Journal of Theoretical Biology. 367: 166-79. PMID 25497475 DOI: 10.1016/j.jtbi.2014.11.021  1
2015 Marino S, Cilfone NA, Mattila JT, Linderman JJ, Flynn JL, Kirschner DE. Macrophage polarization drives granuloma outcome during Mycobacterium tuberculosis infection. Infection and Immunity. 83: 324-38. PMID 25368116 DOI: 10.1128/IAI.02494-14  1
2015 Linderman JJ, Cilfone NA, Pienaar E, Gong C, Kirschner DE. A multi-scale approach to designing therapeutics for tuberculosis Integrative Biology (United Kingdom). 7: 591-609. DOI: 10.1039/c4ib00295d  1
2015 Cilfone NA, Kirschner DE, Linderman JJ. Strategies for Efficient Numerical Implementation of Hybrid Multi-scale Agent-Based Models to Describe Biological Systems Cellular and Molecular Bioengineering. 8: 119-136. DOI: 10.1007/s12195-014-0363-6  1
2014 Kirschner DE, Hunt CA, Marino S, Fallahi-Sichani M, Linderman JJ. Tuneable resolution as a systems biology approach for multi-scale, multi-compartment computational models. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 6: 289-309. PMID 24810243 DOI: 10.1002/wsbm.1270  1
2014 Davis GS, Marino S, Marrs CF, Gilsdorf JR, Dawid S, Kirschner DE. Phase variation and host immunity against high molecular weight (HMW) adhesins shape population dynamics of nontypeable Haemophilus influenzae within human hosts. Journal of Theoretical Biology. 355: 208-18. PMID 24747580 DOI: 10.1016/j.jtbi.2014.04.010  1
2014 Gong C, Linderman JJ, Kirschner D. Harnessing the heterogeneity of T cell differentiation fate to fine-tune generation of effector and memory T cells. Frontiers in Immunology. 5: 57. PMID 24600448 DOI: 10.3389/fimmu.2014.00057  1
2014 Linderman JJ, Kirschner DE. In silico models of M. tuberculosis infection provide a route to new therapies Drug Discovery Today: Disease Models. DOI: 10.1016/j.ddmod.2014.02.006  1
2013 Cilfone NA, Perry CR, Kirschner DE, Linderman JJ. Multi-scale modeling predicts a balance of tumor necrosis factor-α and interleukin-10 controls the granuloma environment during Mycobacterium tuberculosis infection. Plos One. 8: e68680. PMID 23869227 DOI: 10.1371/journal.pone.0068680  1
2013 Mattila JT, Ojo OO, Kepka-Lenhart D, Marino S, Kim JH, Eum SY, Via LE, Barry CE, Klein E, Kirschner DE, Morris SM, Lin PL, Flynn JL. Microenvironments in tuberculous granulomas are delineated by distinct populations of macrophage subsets and expression of nitric oxide synthase and arginase isoforms. Journal of Immunology (Baltimore, Md. : 1950). 191: 773-84. PMID 23749634 DOI: 10.4049/jimmunol.1300113  1
2013 Myers AJ, Marino S, Kirschner DE, Flynn JL. Inoculation dose of Mycobacterium tuberculosis does not influence priming of T cell responses in lymph nodes. Journal of Immunology (Baltimore, Md. : 1950). 190: 4707-16. PMID 23547119 DOI: 10.4049/jimmunol.1203465  1
2013 Repasy T, Lee J, Marino S, Martinez N, Kirschner DE, Hendricks G, Baker S, Wilson AA, Kotton DN, Kornfeld H. Intracellular bacillary burden reflects a burst size for Mycobacterium tuberculosis in vivo. Plos Pathogens. 9: e1003190. PMID 23436998 DOI: 10.1371/journal.ppat.1003190  1
2013 Qin S, Junecko BA, Lucero CM, Klamar CR, Trichel AM, Murphey-Corb MA, Tarwater PM, Kirschner DE, Reinhart TA. Simian immunodeficiency virus infection potently modulates chemokine networks and immune environments in hilar lymph nodes of cynomolgus macaques. Journal of Acquired Immune Deficiency Syndromes (1999). 63: 428-37. PMID 23429503 DOI: 10.1097/QAI.0b013e31828ac85f  1
2013 Fallahi-Sichani M, Marino S, Flynn JL, Linderman JJ, Kirschner DE. A systems biology approach for understanding granuloma formation and function in tuberculosis Systems Biology of Tuberculosis. 127-155. DOI: 10.1007/978-1-4614-4966-9_7  1
2012 Fallahi-Sichani M, Kirschner DE, Linderman JJ. NF-κB Signaling Dynamics Play a Key Role in Infection Control in Tuberculosis. Frontiers in Physiology. 3: 170. PMID 22685435 DOI: 10.3389/fphys.2012.00170  1
2012 Fallahi-Sichani M, Flynn JL, Linderman JJ, Kirschner DE. Differential risk of tuberculosis reactivation among anti-TNF therapies is due to drug binding kinetics and permeability. Journal of Immunology (Baltimore, Md. : 1950). 188: 3169-78. PMID 22379032 DOI: 10.4049/jimmunol.1103298  1
2012 Marino S, Fallahi-Sichani M, Linderman JJ, Kirschner DE. Mathematical Models of Anti-TNF Therapies and their Correlation with Tuberculosis Antibody-Mediated Drug Delivery Systems: Concepts, Technology, and Applications. 83-104. DOI: 10.1002/9781118229019.ch5  1
2011 Mirsky HP, Miller MJ, Linderman JJ, Kirschner DE. Systems biology approaches for understanding cellular mechanisms of immunity in lymph nodes during infection. Journal of Theoretical Biology. 287: 160-70. PMID 21798267 DOI: 10.1016/j.jtbi.2011.06.037  1
2011 Marino S, El-Kebir M, Kirschner D. A hybrid multi-compartment model of granuloma formation and T cell priming in tuberculosis. Journal of Theoretical Biology. 280: 50-62. PMID 21443879 DOI: 10.1016/j.jtbi.2011.03.022  0.36
2011 Fallahi-Sichani M, El-Kebir M, Marino S, Kirschner DE, Linderman JJ. Multiscale computational modeling reveals a critical role for TNF-α receptor 1 dynamics in tuberculosis granuloma formation. Journal of Immunology (Baltimore, Md. : 1950). 186: 3472-83. PMID 21321109 DOI: 10.4049/jimmunol.1003299  1
2011 Marino S, Linderman JJ, Kirschner DE. A multifaceted approach to modeling the immune response in tuberculosis. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 3: 479-89. PMID 21197656 DOI: 10.1002/wsbm.131  1
2010 Qin S, Fallert Junecko BA, Trichel AM, Tarwater PM, Murphey-Corb MA, Kirschner DE, Reinhart TA. Simian immunodeficiency virus infection alters chemokine networks in lung tissues of cynomolgus macaques: association with Pneumocystis carinii infection. The American Journal of Pathology. 177: 1274-85. PMID 20671263 DOI: 10.2353/ajpath.2010.091288  1
2010 Kirschner DE, Young D, Flynn JL. Tuberculosis: global approaches to a global disease. Current Opinion in Biotechnology. 21: 524-31. PMID 20637596 DOI: 10.1016/j.copbio.2010.06.002  0.52
2010 Marino S, Myers A, Flynn JL, Kirschner DE. TNF and IL-10 are major factors in modulation of the phagocytic cell environment in lung and lymph node in tuberculosis: a next-generation two-compartmental model. Journal of Theoretical Biology. 265: 586-98. PMID 20510249 DOI: 10.1016/j.jtbi.2010.05.012  0.52
2010 Fallahi-Sichani M, Schaller MA, Kirschner DE, Kunkel SL, Linderman JJ. Identification of key processes that control tumor necrosis factor availability in a tuberculosis granuloma. Plos Computational Biology. 6: e1000778. PMID 20463877 DOI: 10.1371/journal.pcbi.1000778  1
2010 Linderman JJ, Riggs T, Pande M, Miller M, Marino S, Kirschner DE. Characterizing the dynamics of CD4+ T cell priming within a lymph node. Journal of Immunology (Baltimore, Md. : 1950). 184: 2873-85. PMID 20154206 DOI: 10.4049/jimmunol.0903117  1
2009 Ray JC, Flynn JL, Kirschner DE. Synergy between individual TNF-dependent functions determines granuloma performance for controlling Mycobacterium tuberculosis infection. Journal of Immunology (Baltimore, Md. : 1950). 182: 3706-17. PMID 19265149 DOI: 10.4049/jimmunol.0802297  1
2009 Kirschner DE, Linderman JJ. Mathematical and computational approaches can complement experimental studies of host-pathogen interactions. Cellular Microbiology. 11: 531-9. PMID 19134115 DOI: 10.1111/j.1462-5822.2008.01281.x  1
2008 Hogue IB, Bajaria SH, Fallert BA, Qin S, Reinhart TA, Kirschner DE. The dual role of dendritic cells in the immune response to human immunodeficiency virus type 1 infection. The Journal of General Virology. 89: 2228-39. PMID 18753232 DOI: 10.1099/vir.0.83600-0  1
2008 Marino S, Hogue IB, Ray CJ, Kirschner DE. A methodology for performing global uncertainty and sensitivity analysis in systems biology. Journal of Theoretical Biology. 254: 178-96. PMID 18572196 DOI: 10.1016/j.jtbi.2008.04.011  1
2008 Chang ST, Linderman JJ, Kirschner DE. Effect of multiple genetic polymorphisms on antigen presentation and susceptibility to Mycobacterium tuberculosis infection. Infection and Immunity. 76: 3221-32. PMID 18443099 DOI: 10.1128/IAI.01677-07  1
2008 Qin S, Sui Y, Soloff AC, Junecko BA, Kirschner DE, Murphey-Corb MA, Watkins SC, Tarwater PM, Pease JE, Barratt-Boyes SM, Reinhart TA. Chemokine and cytokine mediated loss of regulatory T cells in lymph nodes during pathogenic simian immunodeficiency virus infection. Journal of Immunology (Baltimore, Md. : 1950). 180: 5530-6. PMID 18390737  1
2008 Ray JC, Wang J, Chan J, Kirschner DE. The timing of TNF and IFN-gamma signaling affects macrophage activation strategies during Mycobacterium tuberculosis infection. Journal of Theoretical Biology. 252: 24-38. PMID 18321531 DOI: 10.1016/j.jtbi.2008.01.010  1
2008 Chakravarty SD, Zhu G, Tsai MC, Mohan VP, Marino S, Kirschner DE, Huang L, Flynn J, Chan J. Tumor necrosis factor blockade in chronic murine tuberculosis enhances granulomatous inflammation and disorganizes granulomas in the lungs. Infection and Immunity. 76: 916-26. PMID 18212087 DOI: 10.1128/IAI.01011-07  1
2008 Riggs T, Walts A, Perry N, Bickle L, Lynch JN, Myers A, Flynn J, Linderman JJ, Miller MJ, Kirschner DE. A comparison of random vs. chemotaxis-driven contacts of T cells with dendritic cells during repertoire scanning. Journal of Theoretical Biology. 250: 732-51. PMID 18068193 DOI: 10.1016/j.jtbi.2007.10.015  1
2008 Fallert BA, Poveda S, Schaefer TM, Pfeifer ME, Sanghavi SK, Watkins SC, Murphey-Corb MA, Tarwater PM, Kirschner DE, Reinhart TA. Virologic and immunologic events in hilar lymph nodes during simian immunodeficiency virus infection: development of polarized inflammation. Journal of Acquired Immune Deficiency Syndromes (1999). 47: 16-26. PMID 17971706 DOI: 10.1097/QAI.0b013e31815cea8b  1
2008 Bauer AL, Hogue IB, Marino S, Kirschner DE. The Effects of HIV-1 Infection on Latent Tuberculosis Mathematical Modelling of Natural Phenomena. 3: 229-266. DOI: 10.1051/mmnp:2008051  0.52
2007 Marino S, Sud D, Plessner H, Lin PL, Chan J, Flynn JL, Kirschner DE. Differences in reactivation of tuberculosis induced from anti-TNF treatments are based on bioavailability in granulomatous tissue. Plos Computational Biology. 3: 1909-24. PMID 17953477 DOI: 10.1371/journal.pcbi.0030194  1
2007 Marino S, Beretta E, Kirschner DE. The role of delays in innate and adaptive immunity to intracellular bacterial infection. Mathematical Biosciences and Engineering : Mbe. 4: 261-88. PMID 17658927  0.36
2007 Kirschner DE, Chang ST, Riggs TW, Perry N, Linderman JJ. Toward a multiscale model of antigen presentation in immunity. Immunological Reviews. 216: 93-118. PMID 17367337 DOI: 10.1111/j.1600-065X.2007.00490.x  1
2007 Segovia-Juarez JL, Colombano S, Kirschner D. Identifying DNA splice sites using hypernetworks with artificial molecular evolution. Bio Systems. 87: 117-24. PMID 17116361 DOI: 10.1016/j.biosystems.2006.09.004  1
2006 Morel PA, Ta'asan S, Morel BF, Kirschner DE, Flynn JL. New insights into mathematical modeling of the immune system. Immunologic Research. 36: 157-65. PMID 17337776 DOI: 10.1385/IR:36:1:157  1
2006 Chang ST, Ghosh D, Kirschner DE, Linderman JJ. Peptide length-based prediction of peptide-MHC class II binding. Bioinformatics (Oxford, England). 22: 2761-7. PMID 17000752 DOI: 10.1093/bioinformatics/btl479  1
2006 Schaefer TM, Fuller CL, Basu S, Fallert BA, Poveda SL, Sanghavi SK, Choi YK, Kirschner DE, Feingold E, Reinhart TA. Increased expression of interferon-inducible genes in macaque lung tissues during simian immunodeficiency virus infection. Microbes and Infection / Institut Pasteur. 8: 1839-50. PMID 16822691 DOI: 10.1016/j.micinf.2006.02.022  1
2006 Sud D, Bigbee C, Flynn JL, Kirschner DE. Contribution of CD8+ T cells to control of Mycobacterium tuberculosis infection. Journal of Immunology (Baltimore, Md. : 1950). 176: 4296-314. PMID 16547267 DOI: 10.4049/jimmunol.176.7.4296  0.52
2006 Ray JC, Kirschner DE. Requirement for multiple activation signals by anti-inflammatory feedback in macrophages. Journal of Theoretical Biology. 241: 276-94. PMID 16460764 DOI: 10.1016/j.jtbi.2005.11.037  1
2005 Ganguli S, Gammack D, Kirschner DE. A metapopulation model of granuloma formation in the lung during infection with mycobacterium tuberculosis. Mathematical Biosciences and Engineering : Mbe. 2: 535-60. PMID 20369939  0.36
2005 Kirschner D, Marino S. Mycobacterium tuberculosis as viewed through a computer. Trends in Microbiology. 13: 206-11. PMID 15866037 DOI: 10.1016/j.tim.2005.03.005  0.36
2005 Chang ST, Linderman JJ, Kirschner DE. Multiple mechanisms allow Mycobacterium tuberculosis to continuously inhibit MHC class II-mediated antigen presentation by macrophages. Proceedings of the National Academy of Sciences of the United States of America. 102: 4530-5. PMID 15767567 DOI: 10.1073/pnas.0500362102  1
2005 Bajaria SH, Kirschner DE. CTL action during HIV-1 is determined VIA interactions with multiple cell types Deterministic and Stochastic Models of Aids Epidemics and Hiv Infections With Intervention. 219-254. DOI: 10.1142/9789812569264_0010  1
2004 Segovia-Juarez JL, Ganguli S, Kirschner D. Identifying control mechanisms of granuloma formation during M. tuberculosis infection using an agent-based model. Journal of Theoretical Biology. 231: 357-76. PMID 15501468 DOI: 10.1016/j.jtbi.2004.06.031  1
2004 Bajaria SH, Webb G, Kirschner DE. Predicting differential responses to structured treatment interruptions during HAART. Bulletin of Mathematical Biology. 66: 1093-118. PMID 15294419 DOI: 10.1016/j.bulm.2003.11.003  1
2004 Marino S, Pawar S, Fuller CL, Reinhart TA, Flynn JL, Kirschner DE. Dendritic cell trafficking and antigen presentation in the human immune response to Mycobacterium tuberculosis. Journal of Immunology (Baltimore, Md. : 1950). 173: 494-506. PMID 15210810  1
2004 Ye P, Kazanjian P, Kunkel SL, Kirschner DE. Lack of good correlation of serum CC-chemokine levels with human immunodeficiency virus-1 disease stage and response to treatment. The Journal of Laboratory and Clinical Medicine. 143: 310-9. PMID 15122175 DOI: 10.1016/j.lab.2004.01.012  1
2004 Ye P, Kirschner DE, Kourtis AP. The thymus during HIV disease: role in pathogenesis and in immune recovery. Current Hiv Research. 2: 177-83. PMID 15078181  1
2004 Joseph IM, Kirschner D. A model for the study of Helicobacter pylori interaction with human gastric acid secretion. Journal of Theoretical Biology. 228: 55-80. PMID 15064083 DOI: 10.1016/j.jtbi.2003.12.004  1
2004 Marino S, Kirschner DE. The human immune response to Mycobacterium tuberculosis in lung and lymph node. Journal of Theoretical Biology. 227: 463-86. PMID 15038983 DOI: 10.1016/j.jtbi.2003.11.023  0.36
2003 Marino S, Ganguli S, Joseph IM, Kirschner DE. The importance of an inter-compartmental delay in a model for human gastric acid secretion. Bulletin of Mathematical Biology. 65: 963-90. PMID 14607284 DOI: 10.1016/S0092-8240(03)00046-6  0.44
2003 Ye P, Kourtis AP, Kirschner DE. Reconstitution of thymic function in HIV-1 patients treated with highly active antiretroviral therapy. Clinical Immunology (Orlando, Fla.). 106: 95-105. PMID 12672400  1
2002 Ye P, Kirschner DE. Measuring emigration of human thymocytes by T-cell receptor excision circles. Critical Reviews in Immunology. 22: 483-97. PMID 12803323  1
2002 Ye P, Kourtis AP, Kirschner DE. The effects of different HIV type 1 strains on human thymic function. Aids Research and Human Retroviruses. 18: 1239-51. PMID 12487812 DOI: 10.1089/088922202320886280  1
2002 Bajaria SH, Webb G, Cloyd M, Kirschner D. Dynamics of naive and memory CD4+ T lymphocytes in HIV-1 disease progression. Journal of Acquired Immune Deficiency Syndromes (1999). 30: 41-58. PMID 12048362 DOI: 10.1097/00126334-200205010-00006  1
2002 Ye P, Kirschner DE. Reevaluation of T cell receptor excision circles as a measure of human recent thymic emigrants. Journal of Immunology (Baltimore, Md. : 1950). 168: 4968-79. PMID 11994448  1
2001 Blower SM, Koelle K, Kirschner DE, Mills J. Live attenuated HIV vaccines: predicting the tradeoff between efficacy and safety. Proceedings of the National Academy of Sciences of the United States of America. 98: 3618-23. PMID 11248127 DOI: 10.1073/pnas.061029998  1
1997 Kirschner D, Lenhart S, Serbin S. Optimal control of the chemotherapy of HIV Journal of Mathematical Biology. 35: 775-792. PMID 9269736  1
1995 Kirschner DE, Blaser MJ. The dynamics of helicobacter pylori infection of the human stomach Journal of Theoretical Biology. 176: 281-290. PMID 7475116 DOI: 10.1006/jtbi.1995.0198  1
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