Eric Meggers - Publications

Affiliations: 
2002-2007 Department of Chemistry University of Pennsylvania, Philadelphia, PA, United States 
 2007- Department of Chemistry Philipps University Marburg, Marburg, Hessen, Germany 
Area:
Organic Chemistry, Inorganic Chemistry, Chemical Biology, Catalysis
Website:
https://www.uni-marburg.de/fb15/ag-meggers

213 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Ye CX, Meggers E. Chiral-at-Ruthenium Catalysts for Nitrene-Mediated Asymmetric C-H Functionalizations. Accounts of Chemical Research. PMID 37071874 DOI: 10.1021/acs.accounts.3c00081  0.322
2021 Jung H, Hong M, Marchini M, Villa M, Steinlandt PS, Huang X, Hemming M, Meggers E, Ceroni P, Park J, Baik MH. Understanding the mechanism of direct visible-light-activated [2 + 2] cycloadditions mediated by Rh and Ir photocatalysts: combined computational and spectroscopic studies. Chemical Science. 12: 9673-9681. PMID 34349938 DOI: 10.1039/d1sc02745j  0.778
2021 Brunen S, Grell Y, Steinlandt PS, Harms K, Meggers E. Bis-Cyclometalated Indazole and Benzimidazole Chiral-at-Iridium Complexes: Synthesis and Asymmetric Catalysis. Molecules (Basel, Switzerland). 26. PMID 33804954 DOI: 10.3390/molecules26071822  0.314
2020 Tan Y, Han F, Hemming M, Wang J, Harms K, Xie X, Meggers E. Asymmetric Ring-Closing Aminooxygenation of Alkenes en Route to 2-Amino-1,3-Diols with Vicinal Stereocenters. Organic Letters. PMID 32806187 DOI: 10.1021/Acs.Orglett.0C02452  0.363
2020 Wang G, Zhou Z, Shen X, Ivlev S, Meggers E. Asymmetric catalysis with a chiral-at-osmium complex. Chemical Communications (Cambridge, England). PMID 32538391 DOI: 10.1039/D0Cc03280H  0.429
2020 Ye CX, Chen S, Han F, Xie X, Ivlev S, Houk KN, Meggers E. Atroposelective Synthesis of Axially Chiral N-Arylpyrroles by Chiral-at-Rhodium Catalysis. Angewandte Chemie (International Ed. in English). PMID 32488954 DOI: 10.1002/Anie.202004799  0.335
2020 Kellert M, Sárosi I, Rajaratnam R, Meggers E, Lönnecke P, Hey-Hawkins E. Ruthenacarborane-Phenanthroline Derivatives as Potential Metallodrugs. Molecules (Basel, Switzerland). 25. PMID 32429279 DOI: 10.3390/Molecules25102322  0.396
2020 Li L, Han F, Nie X, Hong Y, Ivlev S, Meggers E. Complementing Pyridine-2,6-bis(oxazoline) with Cyclometalated N-Heterocyclic Carbene for Asymmetric Ruthenium Catalysis. Angewandte Chemie (International Ed. in English). PMID 32394593 DOI: 10.1002/Anie.202004243  0.398
2020 Zhou Z, Tan Y, Yamahira T, Ivlev S, Xie X, Riedel R, Hemming M, Kimura M, Meggers E. Enantioselective Ring-Closing C–H Amination of Urea Derivatives Chem. 6: 2024-2034. DOI: 10.1016/J.Chempr.2020.05.017  0.368
2019 Zhou Z, Chen S, Hong Y, Winterling E, Tan Y, Hemming M, Harms K, Houk KN, Meggers E. Non--Symmetric Chiral-at-Ruthenium Catalyst for Highly Efficient Enantioselective Intramolecular C(sp)-H Amidation. Journal of the American Chemical Society. PMID 31751132 DOI: 10.1021/Jacs.9B09301  0.393
2019 Steinlandt PS, Zuo W, Harms K, Meggers E. Bis-Cyclometalated Indazole Chiral-at-Rhodium Catalyst for Asymmetric Photoredox Cyanoalkylation. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31541505 DOI: 10.1002/Chem.201903369  0.405
2019 Kuang Y, Wang K, Shi X, Huang X, Meggers E, Wu J. Asymmetric Synthesis of 1,4-Dicarbonyl Compounds from Aldehydes via the Marriage of Hydrogen Atom Transfer Photocatalysis with Chiral Lewis Acid Catalysis. Angewandte Chemie (International Ed. in English). PMID 31538386 DOI: 10.1002/Ange.201910414  0.329
2019 Zhang C, Chen S, Ye CX, Harms K, Zhang L, Houk KN, Meggers E. Asymmetric Photocatalysis by Intramolecular Hydrogen-Atom Transfer in Photoexcited Catalyst-Substrate Complex. Angewandte Chemie (International Ed. in English). PMID 31469211 DOI: 10.1002/Anie.201905647  0.347
2019 Qin J, Zhou Z, Cui T, Hemming M, Meggers E. Enantioselective intramolecular C-H amination of aliphatic azides by dual ruthenium and phosphine catalysis. Chemical Science. 10: 3202-3207. PMID 30996902 DOI: 10.1039/C9Sc00054B  0.397
2019 Huang X, Meggers E. Asymmetric Photocatalysis with Bis-cyclometalated Rhodium Complexes. Accounts of Chemical Research. PMID 30840435 DOI: 10.1021/Acs.Accounts.9B00028  0.437
2019 Hong Y, Jarrige L, Harms K, Meggers E. Chiral-at-Iron Catalyst: Expanding the Chemical Space for Asymmetric Earth-Abundant Metal Catalysis. Journal of the American Chemical Society. PMID 30839201 DOI: 10.1021/Jacs.9B01352  0.389
2019 Grell Y, Demirel N, Harms K, Meggers E. Chiral Bis(oxazoline) Ligands as C2-Symmetric Chiral Auxiliaries for the Synthesis of Enantiomerically Pure Bis-Cyclometalated Rhodium(III) Complexes Organometallics. 38: 3852-3859. DOI: 10.1021/Acs.Organomet.9B00533  0.431
2019 Grell Y, Hong Y, Huang X, Mochizuki T, Xie X, Harms K, Meggers E. Chiral-at-Rhodium Catalyst Containing Two Different Cyclometalating Ligands Organometallics. 38: 3948-3954. DOI: 10.1021/Acs.Organomet.9B00105  0.442
2019 Zhou Z, Nie X, Harms K, Riedel R, Zhang L, Meggers E. Enantioconvergent photoredox radical-radical coupling catalyzed by a chiral-at-rhodium complex Science China Chemistry. 62: 1512-1518. DOI: 10.1007/S11426-019-9584-X  0.363
2018 Zhou Z, Chen S, Qin J, Nie X, Zheng X, Harms K, Riedel R, Houk KN, Meggers E. Catalytic Enantioselective Intramolecular C(sp3)-H Amination of 2-Azidoacetamides. Angewandte Chemie (International Ed. in English). PMID 30475437 DOI: 10.1002/Anie.201811927  0.374
2018 Qin J, Larionov VA, Harms K, Meggers E. Kinetic Resolution of Epoxides with CO2 Catalyzed by a Chiral-at-Iridium Complex. Chemsuschem. PMID 30324685 DOI: 10.1002/Cssc.201802049  0.384
2018 de Assis FF, Huang X, Akiyama M, Pilli RA, Meggers E. Visible-Light-Activated Catalytic Enantioselective β-Alkylation of α,β-Unsaturated 2-Acyl Imidazoles Using Hantzsch Esters as Radical Reservoirs. The Journal of Organic Chemistry. PMID 30028138 DOI: 10.1021/Acs.Joc.8B01588  0.35
2018 Ma J, Lin J, Zhao L, Harms K, Marsch M, Xie X, Meggers E. Synthesis of beta-Substituted gamma-Aminobutyric Acid Derivatives via Enantioselective Photoredox Catalysis. Angewandte Chemie (International Ed. in English). PMID 29714818 DOI: 10.1002/Anie.201804040  0.625
2018 Hu N, Jung H, Zheng Y, Lee J, Zhang L, Ullah Z, Xie X, Harms K, Baik MH, Meggers E. Catalytic Asymmetric Dearomatization by Visible-Light-Activated [2+2] Photocycloaddition. Angewandte Chemie (International Ed. in English). PMID 29624849 DOI: 10.1002/Anie.201802891  0.375
2018 Chen S, Zheng Y, Cui T, Meggers E, Houk KN. Arylketone π-Conjugation Controls Enantioselectivity in Asymmetric Alkynylations Catalyzed by Centrochiral Ruthenium Complexes. Journal of the American Chemical Society. PMID 29577723 DOI: 10.1021/Jacs.8B00485  0.37
2018 Huang X, Lin J, Shen T, Harms K, Marchini M, Ceroni P, Meggers E. Asymmetric [3+2] Photocycloadditions of Cyclopropanes with Alkenes or Alkynes via Visible Light Excitation of Catalyst-Bound Substrates. Angewandte Chemie (International Ed. in English). PMID 29543370 DOI: 10.1002/Anie.201802316  0.427
2018 Ma J, Zhang X, Huang X, Luo S, Meggers E. Preparation of chiral-at-metal catalysts and their use in asymmetric photoredox chemistry. Nature Protocols. 13: 605-632. PMID 29494576 DOI: 10.1038/Nprot.2017.138  0.707
2018 Zhang X, Qin J, Huang X, Meggers E. Sequential asymmetric hydrogenation and photoredox chemistry with a single catalyst Organic Chemistry Frontiers. 5: 166-170. DOI: 10.1039/C7Qo00784A  0.309
2018 Cui T, Qin J, Harms K, Meggers E. Chiral-at-Ruthenium Catalyst with Sterically Demanding Furo[3,2-b ]pyridine Ligands European Journal of Inorganic Chemistry. 2019: 195-198. DOI: 10.1002/Ejic.201801362  0.351
2018 Tan Y, Harms K, Meggers E. A Chiral-at-Metal Iridium Catalyst with Two Simple but Sterically Demanding Cyclometalated N-Heterocyclic Carbene Ligands European Journal of Inorganic Chemistry. 2018: 2500-2504. DOI: 10.1002/Ejic.201800450  0.375
2018 Mietke T, Cruchter T, Larionov VA, Faber T, Harms K, Meggers E. Asymmetric Nazarov Cyclizations Catalyzed by Chiral-at-Metal Complexes Advanced Synthesis & Catalysis. 360: 2093-2100. DOI: 10.1002/Adsc.201701546  0.412
2017 Huang X, Li X, Xie X, Harms K, Riedel R, Meggers E. Catalytic asymmetric synthesis of a nitrogen heterocycle through stereocontrolled direct photoreaction from electronically excited state. Nature Communications. 8: 2245. PMID 29269853 DOI: 10.1038/S41467-017-02148-1  0.382
2017 Ma J, Rosales AR, Huang X, Harms K, Riedel R, Wiest O, Meggers E. Visible-Light-Activated Asymmetric β-C-H Functionalization of Acceptor-Substituted Ketones with 1,2-Dicarbonyl Compounds. Journal of the American Chemical Society. PMID 29161036 DOI: 10.1021/Jacs.7B09152  0.634
2017 Huang X, Luo S, Burghaus O, Webster RD, Harms K, Meggers E. Combining the catalytic enantioselective reaction of visible-light-generated radicals with a by-product utilization system. Chemical Science. 8: 7126-7131. PMID 29147543 DOI: 10.1039/C7Sc02621H  0.326
2017 Chen S, Huang X, Meggers E, Houk KN. Origins of Enantioselectivity in Asymmetric Radical Additions to Octahedral Chiral-at-Rhodium Enolates: A Computational Study. Journal of the American Chemical Society. PMID 29143527 DOI: 10.1021/Jacs.7B08650  0.308
2017 Ma J, Xie X, Meggers E. Catalytic Asymmetric Synthesis of Fluoroalkyl-Containing Compounds Via Three-Component Photoredox Chemistry. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29105857 DOI: 10.1002/Chem.201704619  0.673
2017 Zhou Z, Li Y, Han B, Gong L, Meggers E. Enantioselective catalytic β-amination through proton-coupled electron transfer followed by stereocontrolled radical-radical coupling. Chemical Science. 8: 5757-5763. PMID 28989615 DOI: 10.1039/C7Sc02031G  0.522
2017 Zhang L, Meggers E. Stereogenic-Only-at-Metal Asymmetric Catalysts. Chemistry, An Asian Journal. PMID 28782915 DOI: 10.1002/Asia.201700739  0.39
2017 Luo S, Zhang X, Zheng Y, Harms K, Zhang L, Meggers E. Enantioselective Alkynylation of Aromatic Aldehydes Catalyzed by a Sterically Highly Demanding Chiral-at-Rhodium Lewis Acid. The Journal of Organic Chemistry. PMID 28759724 DOI: 10.1021/Acs.Joc.7B01394  0.362
2017 Yuan W, Zhou Z, Gong L, Meggers E. Asymmetric alkylation of remote C(sp(3))-H bonds by combining proton-coupled electron transfer with chiral Lewis acid catalysis. Chemical Communications (Cambridge, England). PMID 28745750 DOI: 10.1039/C7Cc04941B  0.5
2017 Li Y, Lei M, Yuan W, Meggers E, Gong L. An N-heterocyclic carbene iridium catalyst with metal-centered chirality for enantioselective transfer hydrogenation of imines. Chemical Communications (Cambridge, England). PMID 28677698 DOI: 10.1039/C7Cc04691J  0.55
2017 Huang X, Quinn TR, Harms K, Webster RD, Zhang L, Wiest O, Meggers E. Direct Visible-Light-Excited Asymmetric Lewis Acid Catalysis of Intermolecular [2+2] Photocycloadditions. Journal of the American Chemical Society. PMID 28644024 DOI: 10.1021/Jacs.7B04363  0.374
2017 Mietke T, Cruchter T, Winterling E, Tripp M, Harms K, Meggers E. Suzuki Cross-Coupling for Post-Complexation Derivatization of Non-Racemic Bis-Cyclometalated Iridium(III) Complexes. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 28560718 DOI: 10.1002/Chem.201701758  0.408
2017 Tutkowski B, Meggers E, Wiest O. Understanding Rate Acceleration and Stereoinduction of an Asymmetric Giese Reaction Mediated by a Chiral Rhodium Catalyst. Journal of the American Chemical Society. PMID 28558465 DOI: 10.1021/Jacs.7B01786  0.36
2017 Lin H, Zhou Z, Cai J, Han B, Gong L, Meggers E. Asymmetric Construction of 3,3-Disubstituted Oxindoles Bearing Vicinal Quaternary-Tertiary Carbon Stereocenters Catalyzed by a Chiral-at-Rhodium Complex. The Journal of Organic Chemistry. PMID 28551996 DOI: 10.1021/Acs.Joc.7B00793  0.536
2017 Völker T, Meggers E. Chemical Activation in Blood Serum and Human Cell Culture: Improved Ruthenium Complex for Catalytic Uncaging of Alloc-Protected Amines. Chembiochem : a European Journal of Chemical Biology. PMID 28425643 DOI: 10.1002/Cbic.201700168  0.368
2017 Meggers E. Exploiting Octahedral Stereocenters: From Enzyme Inhibition to Asymmetric Photoredox Catalysis. Angewandte Chemie (International Ed. in English). PMID 28328151 DOI: 10.1002/Anie.201612516  0.411
2017 Feng L, Dai X, Meggers E, Gong L. Three-Component Asymmetric Mannich Reaction Catalyzed by a Lewis Acid with Rhodium-Centered Chirality. Chemistry, An Asian Journal. PMID 28299898 DOI: 10.1002/Asia.201700189  0.529
2017 Zheng Y, Tan Y, Harms K, Zhang L, Meggers E. Octahedral Ruthenium Complex with Exclusive Metal-Centered Chirality for Highly Effective Asymmetric Catalysis. Journal of the American Chemical Society. PMID 28290685 DOI: 10.1021/Jacs.7B01098  0.395
2017 Zhang L, Meggers E. Steering Asymmetric Lewis Acid Catalysis Exclusively with Octahedral Metal-Centered Chirality. Accounts of Chemical Research. PMID 28128920 DOI: 10.1021/Acs.Accounts.6B00586  0.448
2017 Cruchter T, Medvedev MG, Shen X, Mietke T, Harms K, Marsch M, Meggers E. Asymmetric Nucleophilic Catalysis with an Octahedral Chiral-at-Metal Iridium(III) Complex Acs Catalysis. 7: 5151-5162. DOI: 10.1021/Acscatal.7B01296  0.655
2017 Larionov VA, Cruchter T, Mietke T, Meggers E. Polymer-Supported Chiral-at-Metal Lewis Acid Catalysts Organometallics. 36: 1457-1460. DOI: 10.1021/Acs.Organomet.7B00016  0.358
2017 Meggers E. Ausnutzung oktaedrischer Stereozentren: von Enzymhemmung bis hin zu asymmetrischer Photoredoxkatalyse Angewandte Chemie. 129: 5760-5768. DOI: 10.1002/Ange.201612516  0.314
2016 Zhou Z, Li Y, Gong L, Meggers E. Enantioselective 2-Alkylation of 3-Substituted Indoles with Dual Chiral Lewis Acid/Hydrogen-Bond-Mediated Catalyst. Organic Letters. PMID 28026183 DOI: 10.1021/Acs.Orglett.6B03500  0.55
2016 Wang C, Harms K, Meggers E. Catalytic Asymmetric Csp3 -H Functionalization under Photoredox Conditions by Radical Translocation and Stereocontrolled Alkene Addition. Angewandte Chemie (International Ed. in English). PMID 27667745 DOI: 10.1002/Anie.201607305  0.323
2016 Huang X, Webster RD, Harms K, Meggers E. Asymmetric Catalysis with Organic Azides and Diazo Compounds Initiated by Photoinduced Electron Transfer. Journal of the American Chemical Society. PMID 27577929 DOI: 10.1021/Jacs.6B07692  0.354
2016 Ma J, Harms K, Meggers E. Enantioselective rhodium/ruthenium photoredox catalysis en route to chiral 1,2-aminoalcohols. Chemical Communications (Cambridge, England). PMID 27462824 DOI: 10.1039/C6Cc04397F  0.644
2016 Shannan B, Watters A, Chen Q, Mollin S, Dörr M, Meggers E, Xu X, Gimotty PA, Perego M, Li L, Benci J, Krepler C, Brafford P, Zhang J, Wei Z, et al. PIM kinases as therapeutic targets against advanced melanoma. Oncotarget. PMID 27448973 DOI: 10.18632/Oncotarget.10703  0.791
2016 Xu W, Arieno M, Löw H, Huang K, Xie X, Cruchter T, Ma Q, Xi J, Huang B, Wiest O, Gong L, Meggers E. Metal-Templated Design: Enantioselective Hydrogen-Bond-Driven Catalysis Requiring Only Parts-per-Million Catalyst Loading. Journal of the American Chemical Society. PMID 27336458 DOI: 10.1021/Jacs.6B02769  0.533
2016 Meggers E, Zheng Y, Zhang L, Harms K. Enantioselective Alkynylation of 2-Trifluoroacetyl Imidazoles Catalyzed by Bis-Cyclometalated Rhodium(III) Complexes Containing Pinene-Derived Ligands. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27312941 DOI: 10.1002/Chem.201602372  0.45
2016 Song L, Gong L, Meggers E. Asymmetric dual catalysis via fragmentation of a single rhodium precursor complex. Chemical Communications (Cambridge, England). PMID 27231188 DOI: 10.1039/C6Cc03157A  0.543
2016 Huo H, Harms K, Meggers E. Catalytic, Enantioselective Addition of Alkyl Radicals to Alkenes via Visible-Light-Activated Photoredox Catalysis with a Chiral Rhodium Complex. Journal of the American Chemical Society. PMID 27218134 DOI: 10.1021/Jacs.6B03399  0.76
2016 Meggers E, Shen X, Harms K, Marsch M. Rhodium Catalyst Superior Over Iridium Congeners for Enantioselective Radical Amination Activated by Visible Light. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27145893 DOI: 10.1002/Chem.201601572  0.646
2016 Ma J, Shen X, Harms K, Meggers E. Expanding the family of bis-cyclometalated chiral-at-metal rhodium(iii) catalysts with a benzothiazole derivative. Dalton Transactions (Cambridge, England : 2003). PMID 27143346 DOI: 10.1039/C6Dt01063F  0.776
2016 Tian C, Gong L, Meggers E. Chiral-at-metal iridium complex for efficient enantioselective transfer hydrogenation of ketones. Chemical Communications (Cambridge, England). PMID 26911401 DOI: 10.1039/C6Cc00972G  0.579
2016 Huo H, Huang X, Shen X, Harms K, Meggers E. Visible-Light-Activated Enantioselective Perfluoroalkylation with a Chiral Iridium Photoredox Catalyst Synlett. 27: 749-753. DOI: 10.1055/S-0035-1561284  0.796
2016 Citta A, Scalcon V, Göbel P, Bertrand B, Wenzel M, Folda A, Rigobello MP, Meggers E, Casini A. Toward anticancer gold-based compounds targeting PARP-1: a new case study Rsc Advances. 6: 79147-79152. DOI: 10.1039/C6Ra11606J  0.385
2016 Ma Q, Gong L, Meggers E. Enantioselective β-alkylation of pyrroles with the formation of an all-carbon quaternary stereocenter Organic Chemistry Frontiers. 3: 1319-1325. DOI: 10.1039/C6Qo00273K  0.532
2016 Xu W, Shen X, Ma Q, Gong L, Meggers E. Restricted Conformation of a Hydrogen Bond Mediated Catalyst Enables the Highly Efficient Enantioselective Construction of an All-Carbon Quaternary Stereocenter Acs Catalysis. 6: 7641-7646. DOI: 10.1021/Acscatal.6B02080  0.54
2016 Ding X, Tian C, Hu Y, Gong L, Meggers E. Tuning the Basicity of a Metal-Templated Brønsted Base to Facilitate the Enantioselective Sulfa-Michael Addition of Aliphatic Thiols to α,β-Unsaturated N-Acylpyrazoles European Journal of Organic Chemistry. 2016: 887-890. DOI: 10.1002/Ejoc.201501494  0.554
2016 Henker J, Wirmer-Bartoschek J, Bendel LE, Xiang Y, Fu C, Harms K, Schwalbe H, Meggers E. Progress in the Synthesis and Bioactivity of Hexacoordinate Silicon(IV) Complexes European Journal of Inorganic Chemistry. 2016: 5161-5170. DOI: 10.1002/Ejic.201600953  0.407
2016 Helms M, Wang C, Orth B, Harms K, Meggers E. Proline and α-Methylproline as Chiral Auxiliaries for the Synthesis of Enantiopure Bis-Cyclometalated Iridium(III) Complexes European Journal of Inorganic Chemistry. 2016: 2896-2901. DOI: 10.1002/Ejic.201600260  0.415
2016 Huo H, Huang X, Shen X, Harms K, Meggers E. ChemInform Abstract: Visible-Light-Activated Enantioselective Perfluoroalkylation with a Chiral Iridium Photoredox Catalyst. Cheminform. 47. DOI: 10.1002/CHIN.201630155  0.728
2016 Huang K, Ma Q, Shen X, Gong L, Meggers E. Metal-Templated Asymmetric Catalysis: (Z)-1-Bromo-1-Nitrostyrenes as Versatile Substrates for Friedel–Crafts Alkylation of Indoles Asian Journal of Organic Chemistry. 5: 1198-1203. DOI: 10.1002/Ajoc.201600288  0.56
2015 Wang C, Chen LA, Huo H, Shen X, Harms K, Gong L, Meggers E. Asymmetric Lewis acid catalysis directed by octahedral rhodium centrochirality. Chemical Science. 6: 1094-1100. PMID 29560197 DOI: 10.1039/C4Sc03101F  0.802
2015 Wang C, Qin J, Shen X, Riedel R, Harms K, Meggers E. Asymmetric Radical-Radical Cross-Coupling through Visible-Light-Activated Iridium Catalysis. Angewandte Chemie (International Ed. in English). PMID 26629641 DOI: 10.1002/Anie.201509524  0.621
2015 Ritter C, Nett N, Acevedo-Rocha CG, Lonsdale R, Kräling K, Dempwolff F, Hoebenreich S, Graumann PL, Reetz MT, Meggers E. Bioorthogonal Enzymatic Activation of Caged Compounds. Angewandte Chemie (International Ed. in English). 54: 13440-3. PMID 26356324 DOI: 10.1002/Anie.201506739  0.784
2015 Tan Y, Yuan W, Gong L, Meggers E. Aerobic Asymmetric Dehydrogenative Cross-Coupling between Two C sp 3H Groups Catalyzed by a Chiral-at-Metal Rhodium Complex. Angewandte Chemie (International Ed. in English). 54: 13045-8. PMID 26351096 DOI: 10.1002/Anie.201506273  0.538
2015 Huang Y, Song L, Gong L, Meggers E. Asymmetric Synthesis of Hydrocarbazoles Catalyzed by an Octahedral Chiral-at-Rhodium Lewis Acid. Chemistry, An Asian Journal. PMID 26344422 DOI: 10.1002/Asia.201500764  0.543
2015 Rajaratnam R, Martin EK, Dörr M, Harms K, Casini A, Meggers E. Correlation between the Stereochemistry and Bioactivity in Octahedral Rhodium Prolinato Complexes. Inorganic Chemistry. 54: 8111-20. PMID 26251218 DOI: 10.1021/Acs.Inorgchem.5B01349  0.486
2015 Huo H, Wang C, Harms K, Meggers E. Enantioselective, Catalytic Trichloromethylation through Visible-Light-Activated Photoredox Catalysis with a Chiral Iridium Complex. Journal of the American Chemical Society. PMID 26193928 DOI: 10.1021/Jacs.5B06010  0.775
2015 Shen X, Huo H, Wang C, Zhang B, Harms K, Meggers E. Octahedral Chiral-at-Metal Iridium Catalysts: Versatile Chiral Lewis Acids for Asymmetric Conjugate Additions. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 9720-6. PMID 26033287 DOI: 10.1002/Chem.201500922  0.82
2015 Wang C, Zheng Y, Huo H, Röse P, Zhang L, Harms K, Hilt G, Meggers E. Merger of visible light induced oxidation and enantioselective alkylation with a chiral iridium catalyst. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 7355-9. PMID 25832794 DOI: 10.1002/Chem.201500998  0.762
2015 Mollin S, Riedel R, Harms K, Meggers E. Octahedral rhodium(III) complexes as kinase inhibitors: Control of the relative stereochemistry with acyclic tridentate ligands. Journal of Inorganic Biochemistry. 148: 11-21. PMID 25660487 DOI: 10.1016/J.Jinorgbio.2015.01.005  0.84
2015 Meggers E. Asymmetric catalysis activated by visible light. Chemical Communications (Cambridge, England). 51: 3290-301. PMID 25572775 DOI: 10.1039/C4Cc09268F  0.349
2015 Völker T, Meggers E. Transition-metal-mediated uncaging in living human cells—an emerging alternative to photolabile protecting groups. Current Opinion in Chemical Biology. 25: 48-54. PMID 25561021 DOI: 10.1016/J.Cbpa.2014.12.021  0.359
2015 Qin J, Rajaratnam R, Feng L, Salami J, Barber-Rotenberg JS, Domsic J, Reyes-Uribe P, Liu H, Dang W, Berger SL, Villanueva J, Meggers E, Marmorstein R. Development of organometallic S6K1 inhibitors. Journal of Medicinal Chemistry. 58: 305-14. PMID 25356520 DOI: 10.1021/Jm5011868  0.623
2015 Vultur AM, Shannan B, Chen Q, Watters A, Mollin S, Meggers E, Krepler C, Perego M, Li L, Gimotty PA, Xu X, Herlyn M. Abstract 687: Compound screen identifies PIM kinases as therapeutic targets for melanoma Cancer Research. 75: 687-687. DOI: 10.1158/1538-7445.Am2015-687  0.793
2015 Hu Y, Zhou Z, Gong L, Meggers E. Asymmetric aza-Henry reaction to provide oxindoles with quaternary carbon stereocenter catalyzed by a metal-templated chiral Brønsted base Organic Chemistry Frontiers. 2: 968-972. DOI: 10.1039/C5Qo00132C  0.547
2015 Liu J, Gong L, Meggers E. Asymmetric Friedel–Crafts alkylation of indoles with 2-nitro-3-arylacrylates catalyzed by a metal-templated hydrogen bonding catalyst Tetrahedron Letters. 56: 4653-4656. DOI: 10.1016/J.Tetlet.2015.06.046  0.523
2015 Göbel P, Ritterbusch F, Helms M, Bischof M, Harms K, Jung M, Meggers E. Probing chiral recognition of enzyme active sites with octahedral iridium(III) propeller complexes European Journal of Inorganic Chemistry. DOI: 10.1002/Ejic.201500087  0.808
2015 Ritter C, Nett N, Acevedo‐Rocha CG, Lonsdale R, Kräling K, Dempwolff F, Hoebenreich S, Graumann PL, Reetz MT, Meggers E. Bioorthogonale enzymatische Aktivierung maskierter Verbindungen Angewandte Chemie. 127: 13640-13644. DOI: 10.1002/Ange.201506739  0.749
2015 Ding X, Lin H, Gong L, Meggers E. Enantioselective Sulfa-Michael Addition to α,β-Unsaturated γ-Oxoesters Catalyzed by a Metal-Templated Chiral Brønsted Base Asian Journal of Organic Chemistry. 4: 434-437. DOI: 10.1002/Ajoc.201500033  0.565
2014 Huo H, Shen X, Wang C, Zhang L, Röse P, Chen LA, Harms K, Marsch M, Hilt G, Meggers E. Asymmetric photoredox transition-metal catalysis activated by visible light. Nature. 515: 100-3. PMID 25373679 DOI: 10.1038/Nature13892  0.811
2014 Gong L, Chen LA, Meggers E. Asymmetric catalysis mediated by the ligand sphere of octahedral chiral-at-metal complexes. Angewandte Chemie (International Ed. in English). 53: 10868-74. PMID 25156957 DOI: 10.1002/Anie.201404305  0.587
2014 Völker T, Dempwolff F, Graumann PL, Meggers E. Progress towards bioorthogonal catalysis with organometallic compounds. Angewandte Chemie (International Ed. in English). 53: 10536-40. PMID 25138780 DOI: 10.1002/Anie.201404547  0.351
2014 Ma J, Ding X, Hu Y, Huang Y, Gong L, Meggers E. Metal-templated chiral Brønsted base organocatalysis. Nature Communications. 5: 4531. PMID 25072163 DOI: 10.1038/Ncomms5531  0.74
2014 Huo H, Fu C, Wang C, Harms K, Meggers E. Metal-templated enantioselective enamine/H-bonding dual activation catalysis. Chemical Communications (Cambridge, England). 50: 10409-11. PMID 25068974 DOI: 10.1039/C4Cc04636F  0.778
2014 Wähler K, Ludewig A, Szabo P, Harms K, Meggers E. Rhenium Complexes with Red-Light-Induced Anticancer Activity. European Journal of Inorganic Chemistry. 2014: 807-811. PMID 25050081 DOI: 10.1002/Ejic.201301474  0.789
2014 Huo H, Fu C, Harms K, Meggers E. Asymmetric catalysis with substitutionally labile yet stereochemically stable chiral-at-metal iridium(III) complex. Journal of the American Chemical Society. 136: 2990-3. PMID 24754748 DOI: 10.1021/Ja4132505  0.779
2014 Dörr M, Meggers E. Metal complexes as structural templates for targeting proteins. Current Opinion in Chemical Biology. 19: 76-81. PMID 24561508 DOI: 10.1016/J.Cbpa.2014.01.005  0.405
2014 Streib M, Kräling K, Richter K, Xie X, Steuber H, Meggers E. An organometallic inhibitor for the human repair enzyme 7,8-dihydro-8-oxoguanosine triphosphatase. Angewandte Chemie (International Ed. in English). 53: 305-9. PMID 24258965 DOI: 10.1002/Anie.201307849  0.812
2014 Fu C, Harms K, Zhang L, Meggers E. DNA mismatch recognition by a hexacoordinate silicon sandwich-ruthenium hybrid complex Organometallics. 33: 3219-3222. DOI: 10.1021/Om500367A  0.353
2014 Martin EK, Pagano N, Sherlock ME, Harms K, Meggers E. Synthesis and anticancer activity of ruthenium half-sandwich complexes comprising combined metal centrochirality and planar chirality Inorganica Chimica Acta. 423: 530-539. DOI: 10.1016/J.Ica.2014.08.057  0.671
2014 Yao H, Zhang L, Peng Y, Carroll PJ, Gong L, Meggers E. Novel metal-coordinated 1,10-phenanthroline ligands functionalized with a lactam or imide Inorganica Chimica Acta. 421: 489-495. DOI: 10.1016/J.Ica.2014.07.008  0.577
2014 Breiding T, Henker J, Fu C, Xiang Y, Glöckner S, Hofmann P, Harms K, Meggers E. Synthesis and Functionalization of Hexacoordinate (Arenediolato) bis(polypyridyl)silicon(IV) Complexes European Journal of Inorganic Chemistry. 2924-2933. DOI: 10.1002/Ejic.201402024  0.401
2014 Gong L, Chen L, Meggers E. Asymmetrische Katalyse über die Ligandensphäre von oktaedrischen Komplexen mit chiralem Metallzentrum Angewandte Chemie. 126: 11046-11053. DOI: 10.1002/Ange.201404305  0.423
2013 Wähler K, Kräling K, Steuber H, Meggers E. Non-ATP-Mimetic Organometallic Protein Kinase Inhibitor. Chemistryopen. 2: 180-5. PMID 24551564 DOI: 10.1002/Open.201300031  0.783
2013 Chen LA, Tang X, Xi J, Xu W, Gong L, Meggers E. Chiral-at-metal octahedral iridium catalyst for the asymmetric construction of an all-carbon quaternary stereocenter. Angewandte Chemie (International Ed. in English). 52: 14021-5. PMID 24214333 DOI: 10.1002/Anie.201306997  0.456
2013 Cruchter T, Harms K, Meggers E. Strain-promoted azide-alkyne cycloaddition with ruthenium(II)-azido complexes. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 16682-9. PMID 24173767 DOI: 10.1002/Chem.201302502  0.379
2013 Huang B, Wang L, Gong L, Meggers E. Chiral enol oxazolines and thiazolines as auxiliary ligands for the asymmetric synthesis of ruthenium-polypyridyl complexes. Chemistry, An Asian Journal. 8: 2274-80. PMID 23818279 DOI: 10.1002/Asia.201300598  0.49
2013 Gong L, Wenzel M, Meggers E. Chiral-auxiliary-mediated asymmetric synthesis of ruthenium polypyridyl complexes. Accounts of Chemical Research. 46: 2635-44. PMID 23730834 DOI: 10.1021/Ar400083U  0.599
2013 Chen LA, Xu W, Huang B, Ma J, Wang L, Xi J, Harms K, Gong L, Meggers E. Asymmetric catalysis with an inert chiral-at-metal iridium complex. Journal of the American Chemical Society. 135: 10598-601. PMID 23672419 DOI: 10.1021/Ja403777K  0.747
2013 Kastl A, Dieckmann S, Wähler K, Völker T, Kastl L, Merkel AL, Vultur A, Shannan B, Harms K, Ocker M, Parak WJ, Herlyn M, Meggers E. Rhenium complexes with visible-light-induced anticancer activity. Chemmedchem. 8: 924-7. PMID 23568508 DOI: 10.1002/Cmdc.201300060  0.782
2013 Chen LA, Ding X, Gong L, Meggers E. Thioether-based anchimeric assistance for asymmetric coordination chemistry with ruthenium(II) and osmium(II). Dalton Transactions (Cambridge, England : 2003). 42: 5623-6. PMID 23503568 DOI: 10.1039/C3Dt00015J  0.563
2013 Sasmal PK, Streu CN, Meggers E. Metal complex catalysis in living biological systems. Chemical Communications (Cambridge, England). 49: 1581-7. PMID 23250079 DOI: 10.1039/C2Cc37832A  0.812
2013 McQuade DT, O'Brien AG, Dörr M, Rajaratnam R, Eisold U, Monnanda B, Nobuta T, Löhmannsröben HG, Meggers E, Seeberger PH. Continuous synthesis of pyridocarbazoles and initial photophysical and bioprobe characterization Chemical Science. 4: 4067-4070. DOI: 10.1039/C3Sc51846A  0.383
2013 Kraack M, Harms K, Meggers E. Reductive labilization of a cyclometalating ligand applied to auxiliary-mediated asymmetric coordination chemistry Organometallics. 32: 5103-5113. DOI: 10.1021/Om4006627  0.436
2013 Helms M, Lin Z, Gong L, Harms K, Meggers E. Method for the Preparation of Nonracemic Bis-Cyclometalated Iridium(III) Complexes (Eur. J. Inorg. Chem. 24/2013) European Journal of Inorganic Chemistry. 2013: n/a-n/a. DOI: 10.1002/Ejic.201390104  0.679
2013 Helms M, Lin Z, Gong L, Harms K, Meggers E. Method for the preparation of nonracemic bis-cyclometalated iridium(III) complexes European Journal of Inorganic Chemistry. 4164-4172. DOI: 10.1002/Ejic.201300411  0.693
2013 Streib M, Kräling K, Richter K, Xie X, Steuber H, Meggers E. Ein metallorganischer Inhibitor des humanen Reparaturenzyms 7,8-Dihydro-8-oxoguanosin-Triphosphatase Angewandte Chemie. 126: 311-315. DOI: 10.1002/Ange.201307849  0.792
2012 Fu C, Wenzel M, Treutlein E, Harms K, Meggers E. Proline as chiral auxiliary for the economical asymmetric synthesis of ruthenium(II) polypyridyl complexes. Inorganic Chemistry. 51: 10004-11. PMID 22946499 DOI: 10.1021/Ic3015157  0.379
2012 Chen LA, Ma J, Celik MA, Yu HL, Cao Z, Frenking G, Gong L, Meggers E. Active versus passive substituent participation in the auxiliary-mediated asymmetric synthesis of an octahedral metal complex. Chemistry, An Asian Journal. 7: 2523-6. PMID 22915359 DOI: 10.1002/Asia.201200532  0.732
2012 John JK, Paraiso KH, Rebecca VW, Cantini LP, Abel EV, Pagano N, Meggers E, Mathew R, Krepler C, Izumi V, Fang B, Koomen JM, Messina JL, Herlyn M, Smalley KS. GSK3β inhibition blocks melanoma cell/host interactions by downregulating N-cadherin expression and decreasing FAK phosphorylation. The Journal of Investigative Dermatology. 132: 2818-27. PMID 22810307 DOI: 10.1038/Jid.2012.237  0.568
2012 Blanck S, Geisselbrecht Y, Kräling K, Middel S, Mietke T, Harms K, Essen LO, Meggers E. Bioactive cyclometalated phthalimides: design, synthesis and kinase inhibition. Dalton Transactions (Cambridge, England : 2003). 41: 9337-48. PMID 22733119 DOI: 10.1039/C2Dt30940H  0.813
2012 Xiang Y, Fu C, Breiding T, Sasmal PK, Liu H, Shen Q, Harms K, Zhang L, Meggers E. Hydrolytically stable octahedral silicon complexes as bioactive scaffolds: application to the design of DNA intercalators. Chemical Communications (Cambridge, England). 48: 7131-3. PMID 22588541 DOI: 10.1039/C2Cc32506C  0.739
2012 Sasmal PK, Carregal-Romero S, Han AA, Streu CN, Lin Z, Namikawa K, Elliott SL, Köster RW, Parak WJ, Meggers E. Catalytic azide reduction in biological environments. Chembiochem : a European Journal of Chemical Biology. 13: 1116-20. PMID 22514188 DOI: 10.1002/Cbic.201100719  0.783
2012 Merkel AL, Meggers E, Ocker M. PIM1 kinase as a target for cancer therapy. Expert Opinion On Investigational Drugs. 21: 425-36. PMID 22385334 DOI: 10.1517/13543784.2012.668527  0.353
2012 Blanck S, Maksimoska J, Baumeister J, Harms K, Marmorstein R, Meggers E. The art of filling protein pockets efficiently with octahedral metal complexes. Angewandte Chemie (International Ed. in English). 51: 5244-6. PMID 22383326 DOI: 10.1002/Anie.201108865  0.837
2012 Kastl A, Wilbuer A, Merkel AL, Feng L, Di Fazio P, Ocker M, Meggers E. Dual anticancer activity in a single compound: visible-light-induced apoptosis by an antiangiogenic iridium complex. Chemical Communications (Cambridge, England). 48: 1863-5. PMID 22057186 DOI: 10.1039/C1Cc15378A  0.444
2012 Kilah NL, Meggers E. Sixty years young: The diverse biological activities of metal polypyridyl complexes pioneered by Francis P Dwyer Australian Journal of Chemistry. 65: 1325-1332. DOI: 10.1071/Ch12275  0.366
2012 Sasmal PK, Carregal-Romero S, Parak WJ, Meggers E. Light-Triggered Ruthenium-Catalyzed Allylcarbamate Cleavage in Biological Environments Organometallics. 31: 5968-5970. DOI: 10.1021/Om3001668  0.745
2012 Mollin S, Blanck S, Harms K, Meggers E. Cyclometalated phenylquinoline rhodium complexes as protein kinase inhibitors Inorganica Chimica Acta. 393: 261-268. DOI: 10.1016/J.Ica.2012.04.035  0.832
2012 Wenzel M, Meggers E. Chiral (Mercaptophenyl)oxazolines as auxiliaries for asymmetric coordination chemistry European Journal of Inorganic Chemistry. 3168-3175. DOI: 10.1002/Ejic.201200203  0.431
2012 Dieckmann S, Riedel R, Harms K, Meggers E. Pyridocarbazole-Rhodium(III) Complexes as Protein Kinase Inhibitors European Journal of Inorganic Chemistry. 2012: 813-821. DOI: 10.1002/Ejic.201101175  0.796
2012 Blanck S, Maksimoska J, Baumeister J, Harms K, Marmorstein R, Meggers E. Effizientes Ausfüllen von Proteintaschen mit oktaedrischen Metallkomplexen Angewandte Chemie. 124: 5335-5338. DOI: 10.1002/Ange.201108865  0.748
2011 Lin Z, Celik MA, Fu C, Harms K, Frenking G, Meggers E. N-sulfinylcarboximidates as a new class of chiral bidentate ligands: application to asymmetric coordination chemistry. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 12602-5. PMID 21956729 DOI: 10.1002/Chem.201101886  0.605
2011 Blanck S, Cruchter T, Vultur A, Riedel R, Harms K, Herlyn M, Meggers E. Organometallic Pyridylnaphthalimide Complexes as Protein Kinase Inhibitors. Organometallics. 30: 4598-4606. PMID 21918590 DOI: 10.1021/Om200366R  0.814
2011 Johnson AT, Schlegel MK, Meggers E, Essen LO, Wiest O. On the structure and dynamics of duplex GNA. The Journal of Organic Chemistry. 76: 7964-74. PMID 21838272 DOI: 10.1021/Jo201469B  0.68
2011 Feng L, Geisselbrecht Y, Blanck S, Wilbuer A, Atilla-Gokcumen GE, Filippakopoulos P, Kräling K, Celik MA, Harms K, Maksimoska J, Marmorstein R, Frenking G, Knapp S, Essen LO, Meggers E. Structurally sophisticated octahedral metal complexes as highly selective protein kinase inhibitors. Journal of the American Chemical Society. 133: 5976-86. PMID 21446733 DOI: 10.1021/Ja1112996  0.828
2011 Meggers E. From conventional to unusual enzyme inhibitor scaffolds: the quest for target specificity. Angewandte Chemie (International Ed. in English). 50: 2442-8. PMID 21328511 DOI: 10.1002/Anie.201005673  0.359
2011 Lin Z, Gong L, Celik MA, Harms K, Frenking G, Meggers E. Asymmetric coordination chemistry by chiral-auxiliary-mediated dynamic resolution under thermodynamic control. Chemistry, An Asian Journal. 6: 474-81. PMID 21254425 DOI: 10.1002/Asia.201000555  0.687
2011 Atilla-Gokcumen GE, Di Costanzo L, Meggers E. Structure of anticancer ruthenium half-sandwich complex bound to glycogen synthase kinase 3β. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 16: 45-50. PMID 20821241 DOI: 10.1007/S00775-010-0699-X  0.692
2011 Gong L, Müller C, Celik MA, Frenking G, Meggers E. 2-Diphenylphosphino-2′-hydroxy-1,1′-binaphthyl as a chiral auxiliary for asymmetric coordination chemistry New Journal of Chemistry. 35: 788. DOI: 10.1039/C0Nj00787K  0.554
2011 Spencer J, Amin J, Coxhead P, McGeehan J, Richards CJ, Tizzard GJ, Coles SJ, Bingham JP, Hartley JA, Feng L, Meggers E, Guille M. Size does matter. sterically demanding metallocene-substituted 3-methylidene-oxindoles exhibit poor kinase inhibitory action Organometallics. 30: 3177-3181. DOI: 10.1021/Om200278J  0.369
2011 Streu C, Feng L, Carroll PJ, Maksimoska J, Marmorstein R, Meggers E. P-donor ligand containing ruthenium half-sandwich complexes as protein kinase inhibitors Inorganica Chimica Acta. 377: 34-41. DOI: 10.1016/J.Ica.2011.07.032  0.839
2011 Meggers E. Asymmetric Synthesis of Octahedral Coordination Complexes (Eur. J. Inorg. Chem. 19/2011) European Journal of Inorganic Chemistry. 2011: n/a-n/a. DOI: 10.1002/Ejic.201190054  0.434
2011 Meggers E. Asymmetric Synthesis of Octahedral Coordination Complexes European Journal of Inorganic Chemistry. 2011: 2911-2926. DOI: 10.1002/Ejic.201100327  0.447
2010 Mulcahy SP, Gründler K, Frias C, Wagner L, Prokop A, Meggers E. Discovery of a strongly apoptotic ruthenium complex through combinatorial coordination chemistry. Dalton Transactions (Cambridge, England : 2003). 39: 8177-82. PMID 20689887 DOI: 10.1039/C0Dt00034E  0.788
2010 Gong L, Lin Z, Harms K, Meggers E. Isomerization-induced asymmetric coordination chemistry: from auxiliary control to asymmetric catalysis. Angewandte Chemie (International Ed. in English). 49: 7955-7. PMID 20672273 DOI: 10.1002/Anie.201003139  0.67
2010 Gong L, Mulcahy SP, Devarajan D, Harms K, Frenking G, Meggers E. Chiral salicyloxazolines as auxiliaries for the asymmetric synthesis of ruthenium polypyridyl complexes. Inorganic Chemistry. 49: 7692-9. PMID 20666500 DOI: 10.1021/Ic100229E  0.821
2010 He X, Gong L, Kräling K, Gründler K, Frias C, Webster RD, Meggers E, Prokop A, Xia H. Unusual eta2-allene osmacycle with apoptotic properties. Chembiochem : a European Journal of Chemical Biology. 11: 1607-13. PMID 20575131 DOI: 10.1002/Cbic.201000055  0.502
2010 Wilbuer A, Vlecken DH, Schmitz DJ, Kräling K, Harms K, Bagowski CP, Meggers E. Iridium complex with antiangiogenic properties. Angewandte Chemie (International Ed. in English). 49: 3839-42. PMID 20437440 DOI: 10.1002/Anie.201000682  0.473
2010 Schlegel MK, Essen LO, Meggers E. Atomic resolution duplex structure of the simplified nucleic acid GNA. Chemical Communications (Cambridge, England). 46: 1094-6. PMID 20126724 DOI: 10.1039/B916851F  0.676
2010 Meggers E. Chiral auxiliaries as emerging tools for the asymmetric synthesis of octahedral metal complexes. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 752-8. PMID 20013968 DOI: 10.1002/Chem.200902652  0.436
2010 Atilla-Gokcumen GE, Costanzo LD, Meggers E. Structure of anticancer ruthenium half-sandwich complex bound to glycogen synthase kinase 3beta Journal of Biological Inorganic Chemistry. 16: 45-50. DOI: 10.2210/Pdb3M1S/Pdb  0.382
2010 Mulcahy SP, Meggers E. Organometallics as structural scaffolds for enzyme inhibitor design Topics in Organometallic Chemistry. 32: 141-153. DOI: 10.1007/978-3-642-13185-1_6  0.789
2010 Gong L, Lin Z, Harms K, Meggers E. Cover Picture: Isomerization-Induced Asymmetric Coordination Chemistry: From Auxiliary Control to Asymmetric Catalysis (Angew. Chem. Int. Ed. 43/2010) Angewandte Chemie International Edition. 49: 7817-7817. DOI: 10.1002/Anie.201004296  0.668
2010 Wilbuer A, Vlecken DH, Schmitz DJ, Kräling K, Harms K, Bagowski CP, Meggers E. Inside Cover: Iridium Complex with Antiangiogenic Properties (Angew. Chem. Int. Ed. 22/2010) Angewandte Chemie. 49: 3700-3700. DOI: 10.1002/Anie.201001646  0.35
2010 Gong L, Lin Z, Harms K, Meggers E. Titelbild: Isomerization-Induced Asymmetric Coordination Chemistry: From Auxiliary Control to Asymmetric Catalysis (Angew. Chem. 43/2010) Angewandte Chemie. 122: 7987-7987. DOI: 10.1002/Ange.201004296  0.671
2009 Meggers E, Atilla-Gokcumen GE, Gründler K, Frias C, Prokop A. Inert ruthenium half-sandwich complexes with anticancer activity. Dalton Transactions (Cambridge, England : 2003). 10882-8. PMID 20023918 DOI: 10.1039/B917792B  0.701
2009 Pagano N, Wong EY, Breiding T, Liu H, Wilbuer A, Bregman H, Shen Q, Diamond SL, Meggers E. From imide to lactam metallo-pyridocarbazoles: distinct scaffolds for the design of selective protein kinase inhibitors. The Journal of Organic Chemistry. 74: 8997-9009. PMID 19886617 DOI: 10.1021/Jo901641K  0.819
2009 Bullock AN, Russo S, Amos A, Pagano N, Bregman H, Debreczeni JE, Lee WH, von Delft F, Meggers E, Knapp S. Crystal structure of the PIM2 kinase in complex with an organoruthenium inhibitor. Plos One. 4: e7112. PMID 19841674 DOI: 10.1371/Journal.Pone.0007112  0.785
2009 Gong L, Mulcahy SP, Harms K, Meggers E. Chiral-auxiliary-mediated asymmetric synthesis of tris-heteroleptic ruthenium polypyridyl complexes. Journal of the American Chemical Society. 131: 9602-3. PMID 19555100 DOI: 10.1021/Ja9031665  0.829
2009 Schlegel MK, Meggers E. Improved phosphoramidite building blocks for the synthesis of the simplified nucleic acid GNA. The Journal of Organic Chemistry. 74: 4615-8. PMID 19441799 DOI: 10.1021/Jo900365A  0.69
2009 Xie P, Streu C, Qin J, Bregman H, Pagano N, Meggers E, Marmorstein R. The crystal structure of BRAF in complex with an organoruthenium inhibitor reveals a mechanism for inhibition of an active form of BRAF kinase. Biochemistry. 48: 5187-98. PMID 19371126 DOI: 10.1021/Bi802067U  0.815
2009 Anand R, Maksimoska J, Pagano N, Wong EY, Gimotty PA, Diamond SL, Meggers E, Marmorstein R. Toward the development of a potent and selective organoruthenium mammalian sterile 20 kinase inhibitor. Journal of Medicinal Chemistry. 52: 1602-11. PMID 19226137 DOI: 10.1021/Jm8005806  0.818
2009 Meggers E. Targeting proteins with metal complexes. Chemical Communications (Cambridge, England). 1001-10. PMID 19225621 DOI: 10.1039/B813568A  0.453
2009 Schlegel MK, Zhang L, Pagano N, Meggers E. Metal-mediated base pairing within the simplified nucleic acid GNA. Organic & Biomolecular Chemistry. 7: 476-82. PMID 19156312 DOI: 10.1039/B816142A  0.76
2009 Schlegel MK, Xie X, Zhang L, Meggers E. Insight into the high duplex stability of the simplified nucleic acid GNA. Angewandte Chemie (International Ed. in English). 48: 960-3. PMID 19130516 DOI: 10.1002/Anie.200803472  0.664
2009 Xie X, Mulcahy SP, Meggers E. Strategy for the stereochemical assignment of tris-heteroleptic Ru(II) complexes by NMR spectroscopy. Inorganic Chemistry. 48: 1053-61. PMID 19105744 DOI: 10.1021/Ic801744A  0.779
2008 Streu C, Carroll PJ, Kohli RK, Meggers E. Synthesis of cyclopentadienyl ruthenium complexes bearing pendant chelating picolinates through an electrophilic precursor. Journal of Organometallic Chemistry. 693: 551-556. PMID 19190711 DOI: 10.1016/J.Jorganchem.2007.11.024  0.78
2008 Atilla-Gokcumen GE, Pagano N, Streu C, Maksimoska J, Filippakopoulos P, Knapp S, Meggers E. Extremely tight binding of a ruthenium complex to glycogen synthase kinase 3. Chembiochem : a European Journal of Chemical Biology. 9: 2933-6. PMID 19035373 DOI: 10.1002/Cbic.200800489  0.81
2008 Maksimoska J, Feng L, Harms K, Yi C, Kissil J, Marmorstein R, Meggers E. Targeting large kinase active site with rigid, bulky octahedral ruthenium complexes. Journal of the American Chemical Society. 130: 15764-5. PMID 18973295 DOI: 10.1021/Ja805555A  0.827
2008 Schlegel MK, Essen LO, Meggers E. Duplex structure of a minimal nucleic acid. Journal of the American Chemical Society. 130: 8158-9. PMID 18529005 DOI: 10.1021/Ja802788G  0.686
2008 Xie P, Williams DS, Atilla-Gokcumen GE, Milk L, Xiao M, Smalley KS, Herlyn M, Meggers E, Marmorstein R. Structure-based design of an organoruthenium phosphatidyl-inositol-3-kinase inhibitor reveals a switch governing lipid kinase potency and selectivity. Acs Chemical Biology. 3: 305-16. PMID 18484710 DOI: 10.1021/Cb800039Y  0.816
2008 Maksimoska J, Williams DS, Atilla-Gokcumen GE, Smalley KS, Carroll PJ, Webster RD, Filippakopoulos P, Knapp S, Herlyn M, Meggers E. Similar biological activities of two isostructural ruthenium and osmium complexes. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 4816-22. PMID 18425743 DOI: 10.1002/Chem.200800294  0.829
2008 David SS, Meggers E. Inorganic chemical biology: from small metal complexes in biological systems to metalloproteins. Current Opinion in Chemical Biology. 12: 194-6. PMID 18374664 DOI: 10.1016/J.Cbpa.2008.03.008  0.423
2008 Mulcahy SP, Li S, Korn R, Xie X, Meggers E. Solid-phase synthesis of tris-heteroleptic ruthenium(II) complexes and application to acetylcholinesterase inhibition. Inorganic Chemistry. 47: 5030-2. PMID 18373338 DOI: 10.1021/Ic800080B  0.794
2008 Atilla-Gokcumen GE, Pagano N, Streu C, Maksimoska J, Filippakopoulos P, Knapp S, Meggers E. Cover Picture: Extremely Tight Binding of a Ruthenium Complex to Glycogen Synthase Kinase 3 (ChemBioChem 18/2008) Chembiochem. 9: 2897-2897. DOI: 10.1002/Cbic.200890070  0.816
2007 Meggers E. Exploring biologically relevant chemical space with metal complexes. Current Opinion in Chemical Biology. 11: 287-92. PMID 17548234 DOI: 10.1016/J.Cbpa.2007.05.013  0.368
2007 Schlegel MK, Peritz AE, Kittigowittana K, Zhang L, Meggers E. Duplex formation of the simplified nucleic acid GNA. Chembiochem : a European Journal of Chemical Biology. 8: 927-32. PMID 17465439 DOI: 10.1002/Cbic.200600435  0.681
2007 Pagano N, Maksimoska J, Bregman H, Williams DS, Webster RD, Xue F, Meggers E. Ruthenium half-sandwich complexes as protein kinase inhibitors: derivatization of the pyridocarbazole pharmacophore ligand. Organic & Biomolecular Chemistry. 5: 1218-27. PMID 17406720 DOI: 10.1039/B700433H  0.83
2007 Williams DS, Carroll PJ, Meggers E. Platinum complex as a nanomolar protein kinase inhibitor. Inorganic Chemistry. 46: 2944-6. PMID 17375909 DOI: 10.1021/Ic062055T  0.777
2007 Smalley KS, Contractor R, Haass NK, Kulp AN, Atilla-Gokcumen GE, Williams DS, Bregman H, Flaherty KT, Soengas MS, Meggers E, Herlyn M. An organometallic protein kinase inhibitor pharmacologically activates p53 and induces apoptosis in human melanoma cells. Cancer Research. 67: 209-17. PMID 17210701 DOI: 10.1158/0008-5472.Can-06-1538  0.776
2007 Meggers E, Atilla-Gokcumen GE, Bregman H, Maksimoska J, Mulcahy SP, Pagano N, Williams DS. Exploring chemical space with organometallics: Ruthenium complexes as protein kinase inhibitors Synlett. 1177-1189. DOI: 10.1055/S-2007-973893  0.813
2007 Meggers E, Atilla-Gokcumen GE, Bregman H, Maksimoska J, Mulcahy SP, Pagano N, Williams DS. Exploring Chemical Space with Organometallics: Ruthenium Complexes as Protein Kinase Inhibitors Cheminform. 38. DOI: 10.1002/chin.200731205  0.819
2006 Mulcahy SP, Carroll PJ, Meggers E. Synthesis and cyclometalation of a pyrido[3,2-e]-2,10b-diaza-cyclopenta[c]fluorene-1,3-dione scaffold. Tetrahedron Letters. 47: 8877-8880. PMID 18071577 DOI: 10.1016/J.Tetlet.2006.10.054  0.791
2006 Bregman H, Meggers E. Ruthenium half-sandwich complexes as protein kinase inhibitors: an N-succinimidyl ester for rapid derivatizations of the cyclopentadienyl moiety. Organic Letters. 8: 5465-8. PMID 17107048 DOI: 10.1021/Ol0620646  0.771
2006 Atilla-Gokcumen GE, Williams DS, Bregman H, Pagano N, Meggers E. Organometallic compounds with biological activity: a very selective and highly potent cellular inhibitor for glycogen synthase kinase 3. Chembiochem : a European Journal of Chemical Biology. 7: 1443-50. PMID 16858717 DOI: 10.1002/Cbic.200600117  0.812
2006 Streu C, Meggers E. Ruthenium-induced allylcarbamate cleavage in living cells. Angewandte Chemie (International Ed. in English). 45: 5645-8. PMID 16856188 DOI: 10.1002/Anie.200601752  0.76
2006 Bregman H, Carroll PJ, Meggers E. Rapid access to unexplored chemical space by ligand scanning around a ruthenium center: discovery of potent and selective protein kinase inhibitors. Journal of the American Chemical Society. 128: 877-84. PMID 16417378 DOI: 10.1021/Ja055523R  0.778
2006 Debreczeni JE, Bullock AN, Atilla GE, Williams DS, Bregman H, Knapp S, Meggers E. Ruthenium half-sandwich complexes bound to protein kinase Pim-1. Angewandte Chemie (International Ed. in English). 45: 1580-5. PMID 16381041 DOI: 10.1002/Anie.200503468  0.826
2006 Debreczeni JÉ, Bullock AN, Atilla GE, Williams DS, Bregman H, Knapp S, Meggers E. Ruthenium Half-Sandwich Complexes Bound to Protein Kinase Pim-1 Angewandte Chemie. 118: 1610-1615. DOI: 10.1002/ange.200503468  0.827
2005 Williams DS, Atilla GE, Bregman H, Arzoumanian A, Klein PS, Meggers E. Switching on a signaling pathway with an organoruthenium complex. Angewandte Chemie (International Ed. in English). 44: 1984-7. PMID 15742314 DOI: 10.1002/Anie.200462501  0.833
2005 Bregman H, Williams DS, Meggers E. Pyrido[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-diones: Synthesis, cyclometalation, and protein kinase inhibition Synthesis. 1521-1527. DOI: 10.1055/S-2005-865331  0.758
2004 Bregman H, Williams DS, Atilla GE, Carroll PJ, Meggers E. An organometallic inhibitor for glycogen synthase kinase 3. Journal of the American Chemical Society. 126: 13594-5. PMID 15493898 DOI: 10.1021/Ja046049C  0.835
2004 Zhang L, Carroll P, Meggers E. Ruthenium complexes as protein kinase inhibitors. Organic Letters. 6: 521-3. PMID 14961613 DOI: 10.1021/Ol036283S  0.491
2004 Zimmermann N, Meggers E, Schultz PG. A second-generation copper(II)-mediated metallo-DNA-base pair. Bioorganic Chemistry. 32: 13-25. PMID 14700559 DOI: 10.1016/J.Bioorg.2003.09.001  0.462
2003 Chin JW, Cropp TA, Chu S, Meggers E, Schultz PG. Progress toward an expanded eukaryotic genetic code. Chemistry & Biology. 10: 511-9. PMID 12837384 DOI: 10.1016/S1074-5521(03)00123-6  0.614
2002 Zimmermann N, Meggers E, Schultz PG. A novel silver(i)-mediated DNA base pair. Journal of the American Chemical Society. 124: 13684-5. PMID 12431092 DOI: 10.1021/Ja0279951  0.43
2001 Atwell S, Meggers E, Spraggon G, Schultz PG. Structure of a copper-mediated base pair in DNA. Journal of the American Chemical Society. 123: 12364-7. PMID 11734038 DOI: 10.1021/Ja011822E  0.73
2000 Meggers E, Dussy A, Schäfer T, Giese B. Electron transfer in DNA from guanine and 8-oxoguanine to a radical cation of the carbohydrate backbone. Chemistry (Weinheim An Der Bergstrasse, Germany). 6: 485-92. PMID 10747415 DOI: 10.1002/(Sici)1521-3765(20000204)6:3<485::Aid-Chem485>3.0.Co;2-A  0.442
2000 Meggers E, Holland PL, Tolman WB, Romesberg FE, Schultz PG. A novel copper-mediated DNA base pair [6] Journal of the American Chemical Society. 122: 10714-10715. DOI: 10.1021/Ja0025806  0.605
1999 Giese B, Wessely S, Spormann M, Lindemann U, Meggers E, Michel-Beyerle ME. On the Mechanism of Long-Range Electron Transfer through DNA. Angewandte Chemie (International Ed. in English). 38: 996-998. PMID 29711867 DOI: 10.1002/(Sici)1521-3773(19990401)38:7<996::Aid-Anie996>3.0.Co;2-4  0.433
1999 Meggers E, Giese B. Hole transport between G bases in DNA Nucleosides and Nucleotides. 18: 1317-1318. DOI: 10.1080/07328319908044702  0.419
1999 Giese B, Wessely S, Spormann M, Lindemann U, Meggers E, Michel-Beyerle ME. On the mechanism of long-range electron transfer through DNA Angewandte Chemie - International Edition. 38: 996-998. DOI: 10.1002/(SICI)1521-3773(19990401)38:7<996::AID-ANIE996>3.0.CO;2-4  0.344
1999 Giese B, Wessely S, Spormann M, Lindemann U, Meggers E, Michel-Beyerle ME. Zum Mechanismus des weitreichenden Elektronentransports durch DNA Angewandte Chemie. 111: 1050-1052. DOI: 10.1002/(Sici)1521-3757(19990401)111:7<1050::Aid-Ange1050>3.0.Co;2-9  0.42
1998 Meggers E, Kusch D, Spichty M, Wille U, Giese B. Electron Transfer through DNA in the Course of Radical-Induced Strand Cleavage. Angewandte Chemie (International Ed. in English). 37: 460-462. PMID 29711175 DOI: 10.1002/(Sici)1521-3773(19980302)37:4<460::Aid-Anie460>3.0.Co;2-U  0.444
1998 Meggers E, Michel-Beyerle ME, Giese B. Sequence Dependent Long Range Hole Transport in DNA Journal of the American Chemical Society. 120: 12950-12955. DOI: 10.1021/Ja983092P  0.439
1998 Dussy A, Meggers E, Giese B. Spontaneous Cleavage of 4‘-DNA Radicals under Aerobic Conditions:  Apparent Discrepancy between Trapping Rates and Cleavage Products Journal of the American Chemical Society. 120: 7399-7403. DOI: 10.1021/Ja980036F  0.431
1998 Meggers E, Kusch D, Spichty M, Wille U, Giese B. Elektronentransfer durch DNA beim radikalinduzierten Strangbruch Angewandte Chemie. 110: 473-476. DOI: 10.1002/(Sici)1521-3757(19980216)110:4<473::Aid-Ange473>3.0.Co;2-B  0.415
1997 Meggers E, Kusch D, Giese B. An Efficient Synthesis of Enantiomerically Pure ?- and ?-Ruthenium(II)-Labelled Oligonucleotides Helvetica Chimica Acta. 80: 640-652. DOI: 10.1002/Hlca.19970800303  0.505
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