Michael K. Fenwick, Ph.D. - Publications

Affiliations: 
2005 Cornell University, Ithaca, NY, United States 
Area:
Chemical Engineering, Molecular Physics, Immunology, Oncology, Medical Biophysics

23 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Fenwick MK, Ealick SE. Crystal structures of the iron sulfur cluster dependent quinolinate synthase in complex with dihydroxyacetone phosphate, iminoaspartate analogs, and quinolinate. Biochemistry. PMID 27404889 DOI: 10.1021/acs.biochem.6b00626  1
2016 Fenwick MK, Philmus B, Begley TP, Ealick SE. Burkholderia glumae ToxA is a Dual Specificity Methyltransferase that Catalyzes the Last Two Steps of Toxoflavin Biosynthesis. Biochemistry. PMID 27070241 DOI: 10.1021/acs.biochem.6b00167  1
2015 Mehta AP, Abdelwahed SH, Fenwick MK, Hazra AB, Taga ME, Zhang Y, Ealick SE, Begley TP. Anaerobic 5-Hydroxybenzimidazole formation from aminoimidazole ribotide: an unanticipated intersection of thiamin and vitamin B12 biosynthesis. Journal of the American Chemical Society. PMID 26237670 DOI: 10.1021/jacs.5b03576  1
2015 Fenwick MK, Mehta AP, Zhang Y, Abdelwahed SH, Begley TP, Ealick SE. Non-canonical active site architecture of the radical SAM thiamin pyrimidine synthase. Nature Communications. 6: 6480. PMID 25813242 DOI: 10.1038/ncomms7480  1
2013 Ahmed AH, Ptak CP, Fenwick MK, Hsieh CL, Weiland GA, Oswald RE. Dynamics of cleft closure of the GluA2 ligand-binding domain in the presence of full and partial agonists revealed by hydrogen-deuterium exchange. The Journal of Biological Chemistry. 288: 27658-66. PMID 23940029 DOI: 10.1074/jbc.M113.495564  1
2012 Lai RY, Huang S, Fenwick MK, Hazra A, Zhang Y, Rajashankar K, Philmus B, Kinsland C, Sanders JM, Ealick SE, Begley TP. Thiamin pyrimidine biosynthesis in Candida albicans : a remarkable reaction between histidine and pyridoxal phosphate. Journal of the American Chemical Society. 134: 9157-9. PMID 22568620 DOI: 10.1021/ja302474a  1
2012 Philmus B, Abdelwahed S, Williams HJ, Fenwick MK, Ealick SE, Begley TP. Identification of the product of toxoflavin lyase: degradation via a Baeyer-Villiger oxidation. Journal of the American Chemical Society. 134: 5326-30. PMID 22304755 DOI: 10.1021/ja211759n  1
2011 Fenwick MK, Philmus B, Begley TP, Ealick SE. Toxoflavin lyase requires a novel 1-His-2-carboxylate facial triad. Biochemistry. 50: 1091-100. PMID 21166463 DOI: 10.1021/bi101741v  1
2010 Fenwick MK, Oswald RE. On the mechanisms of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor binding to glutamate and kainate. The Journal of Biological Chemistry. 285: 12334-43. PMID 20110361 DOI: 10.1074/jbc.M109.086371  1
2009 Fenwick MK, Escobedo FA. Exploration of factors affecting the onset and maturation course of follicular lymphoma through simulations of the germinal center. Bulletin of Mathematical Biology. 71: 1432-62. PMID 19412639 DOI: 10.1007/s11538-009-9408-8  1
2009 Ahmed AH, Thompson MD, Fenwick MK, Romero B, Loh AP, Jane DE, Sondermann H, Oswald RE. Mechanisms of antagonism of the GluR2 AMPA receptor: structure and dynamics of the complex of two willardiine antagonists with the glutamate binding domain. Biochemistry. 48: 3894-903. PMID 19284741 DOI: 10.1021/bi900107m  1
2009 Velez-Vega C, Fenwick MK, Escobedo FA. Simulated mutagenesis of the hypervariable loops of a llama VHH domain for the recovery of canonical conformations. The Journal of Physical Chemistry. B. 113: 1785-95. PMID 19132876 DOI: 10.1021/jp805866j  1
2008 Fenwick MK. A direct multiple histogram reweighting method for optimal computation of the density of states. The Journal of Chemical Physics. 129: 125106. PMID 19045067 DOI: 10.1063/1.2981800  1
2008 Maltsev AS, Ahmed AH, Fenwick MK, Jane DE, Oswald RE. Mechanism of partial agonism at the GluR2 AMPA receptor: Measurements of lobe orientation in solution. Biochemistry. 47: 10600-10. PMID 18795801 DOI: 10.1021/bi800843c  1
2008 Fenwick MK, Oswald RE. NMR spectroscopy of the ligand-binding core of ionotropic glutamate receptor 2 bound to 5-substituted willardiine partial agonists. Journal of Molecular Biology. 378: 673-85. PMID 18387631 DOI: 10.1016/j.jmb.2008.03.012  1
2008 Velez Vega CA, Fenwick MK, Escobedo FA. Simulated mutagenesis and structural analysis for protein fragment engineering Aiche Annual Meeting, Conference Proceedings 1
2007 Fenwick MK, Oswald RE. Backbone chemical shift assignment of a glutamate receptor ligand binding domain in complexes with five partial agonists. Biomolecular Nmr Assignments. 1: 241-3. PMID 19636875 DOI: 10.1007/s12104-007-9067-3  1
2007 Oswald RE, Ahmed A, Fenwick MK, Loh AP. Structure of glutamate receptors. Current Drug Targets. 8: 573-82. PMID 17504102 DOI: 10.2174/138945007780618526  1
2006 Fenwick MK. Accurate estimation of the density of states from Monte Carlo transition probability data. The Journal of Chemical Physics. 125: 144905. PMID 17042648 DOI: 10.1063/1.2358345  1
2004 Fenwick MK, Escobedo FA. On the use of Bennett's acceptance ratio method in multi-canonical-type simulations. The Journal of Chemical Physics. 120: 3066-74. PMID 15268459 DOI: 10.1063/1.1641000  1
2003 Fenwick MK, Escobedo FA. Hybrid Monte Carlo with multidimensional replica exchanges: conformational equilibria of the hypervariable regions of a llama VHH antibody domain. Biopolymers. 68: 160-77. PMID 12548621 DOI: 10.1002/bip.10291  1
2003 Fenwick MK, Escobedo FA. Expanded ensemble and replica exchange methods for simulation of protein-like systems Journal of Chemical Physics. 119: 11998-12010. DOI: 10.1063/1.1624822  1
2000 Sholl DS, Fenwick MK, Atman E, Prieve DC. Brownian dynamics simulation of the motion of a rigid sphere in a viscous fluid very near a wall Journal of Chemical Physics. 113: 9268-9278. DOI: 10.1063/1.1320829  1
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